Receptor
PDB id Resolution Class Description Source Keywords
1jz7 1.5 Å EC: 3.2.1.23 E. COLI (LACZ) BETA-GALACTOSIDASE IN COMPLEX WITH GALACTOSE ESCHERICHIA COLI TIM BARREL (ALPHA/BETA BARREL) JELLY-ROLL BARREL IMMUNOGLOBULIN BETA SUPERSANDWICH HYDROLASE
Ref.: A STRUCTURAL VIEW OF THE ACTION OF ESCHERICHIA COLI (LACZ) BETA-GALACTOSIDASE BIOCHEMISTRY V. 40 14781 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data Chemaxon Viewer Molecular Weight (Da) Formula SMILES
DMS A:8401;
A:8402;
A:8403;
A:8404;
A:8405;
A:8406;
A:8407;
A:8408;
A:8409;
A:8410;
A:8411;
A:8412;
A:8413;
A:8414;
A:8415;
A:8416;
A:8420;
A:8421;
A:8425;
A:8501;
A:8502;
A:8504;
A:8506;
B:8401;
B:8402;
B:8403;
B:8404;
B:8405;
B:8406;
B:8407;
B:8408;
B:8409;
B:8410;
B:8411;
B:8412;
B:8414;
B:8416;
B:8417;
B:8420;
B:8421;
B:8425;
B:8501;
B:8502;
B:8504;
B:8601;
C:8401;
C:8402;
C:8403;
C:8404;
C:8405;
C:8407;
C:8408;
C:8409;
C:8410;
C:8411;
C:8412;
C:8413;
C:8414;
C:8415;
C:8416;
C:8417;
C:8420;
C:8421;
C:8425;
C:8501;
C:8504;
C:8506;
C:8602;
D:8401;
D:8402;
D:8403;
D:8404;
D:8405;
D:8406;
D:8408;
D:8409;
D:8410;
D:8411;
D:8412;
D:8413;
D:8414;
D:8415;
D:8416;
D:8421;
D:8425;
D:8501;
D:8506;
D:8508;
D:8701;
D:8703;
D:8705;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data 78.133 C2 H6 O S CS(=O...
GAL A:2001;
A:2002;
B:2001;
B:2002;
C:2001;
C:2002;
D:2001;
D:2002;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
Ki ~ 400 mM 164.157 C6 H12 O6 O1C(C...
MG A:3001;
A:3002;
A:3005;
A:3105;
B:3001;
B:3002;
B:3105;
C:3001;
C:3002;
C:3006;
C:3105;
D:3001;
D:3002;
D:3005;
D:3105;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data 24.305 Mg [Mg+2...
NA A:3101;
A:3102;
A:3103;
A:3104;
B:3101;
B:3102;
B:3103;
B:3104;
C:3101;
C:3102;
C:3103;
C:3104;
D:3101;
D:3102;
D:3103;
D:3104;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data 22.99 Na [Na+]
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3VDB 2.05 Å EC: 3.2.1.23 E. COLI (LACZ) BETA-GALACTOSIDASE (N460T) IN COMPLEX WITH GALACTONOLACTONE ESCHERICHIA COLI TRANSITION STATE STABILIZATION SUBSTRATE BINDING 2-STAGE BTIM BARREL (ALPHA/BETA BARREL) JELLY-ROLL BARREL IMMUNOGLBETA SUPERSANDWICH GLYCOSIDASE HYDROLASE
Ref.: SUBSTITUTION FOR ASN460 CRIPPLES {BETA}-GALACTOSIDA (ESCHERICHIA COLI) BY INCREASING SUBSTRATE AFFINITY DECREASING TRANSITION STATE STABILITY. ARCH.BIOCHEM.BIOPHYS. V. 521 51 2012
Members (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 3T08 Ki = 0.91 mM IPT C9 H18 O5 S CC(C)S[C@H....
2 1JZ8 - LAK C12 H22 O11 O1C(OCC2OC....
3 3I3B Ki = 5.9 mM 149 C6 H10 O6 C([C@@H]1[....
4 1PX4 Ki = 0.59 mM IPT C9 H18 O5 S CC(C)S[C@H....
5 1JYW - 147 C12 H15 N O8 ON(O)c1ccc....
6 3VD9 Ki = 0.1 mM IPT C9 H18 O5 S CC(C)S[C@H....
7 4DUW - LAK C12 H22 O11 O1C(OCC2OC....
8 3T0B Ki = 0.05 mM IPT C9 H18 O5 S CC(C)S[C@H....
9 1JZ5 - 149 C6 H10 O6 C([C@@H]1[....
10 1JYV - 145 C12 H15 N O8 c1ccc(c(c1....
11 1JYX - IPT C9 H18 O5 S CC(C)S[C@H....
12 3T09 Ki = 0.16 mM 149 C6 H10 O6 C([C@@H]1[....
13 3T2Q Ki = 0.22 mM 149 C6 H10 O6 C([C@@H]1[....
14 1JZ6 - GTZ C6 H10 N4 O4 C([C@@H]1[....
15 3VD4 Ki = 0.015 mM IPT C9 H18 O5 S CC(C)S[C@H....
16 1JYN - LAT C12 H22 O11 O(C1OC(C(O....
17 4DUX - 0MK C5 H10 O5 C1[C@@H]([....
18 1JZ7 Ki ~ 400 mM GAL C6 H12 O6 O1C(C(O)C(....
19 3I3D Ki = 10.3 mM IPT C9 H18 O5 S CC(C)S[C@H....
20 3CZJ - 149 C6 H10 O6 C([C@@H]1[....
21 3VDB Ki = 0.012 mM 149 C6 H10 O6 C([C@@H]1[....
22 3T0D Ki = 4.3 mM 149 C6 H10 O6 C([C@@H]1[....
23 3DYO Ki = 5 mM IPT C9 H18 O5 S CC(C)S[C@H....