Receptor
PDB id Resolution Class Description Source Keywords
1bnn 2.3 Å EC: 4.2.1.1 CARBONIC ANHYDRASE II INHIBITOR HOMO SAPIENS CO2 HYDRATION ZINC ENZYME LYASE
Ref.: STRUCTURAL ANALYSIS OF INHIBITOR BINDING TO HUMAN CARBONIC ANHYDRASE II. PROTEIN SCI. V. 7 2483 1998
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data Chemaxon Viewer Molecular Weight (Da) Formula SMILES
AL1 A:555;
Valid;
none;
Kd = 0.1 nM 374.456 C13 H14 N2 O5 S3 COc1c...
ZN A:262;
Part of Protein;
none;
submit data 65.409 Zn [Zn+2...
View in 3D viewer
Show:
Background:
Molecular Surface:
Left mouse click:
Jmol Command:
Jmol viewer:
- Jmol Mouse manual
- Jmol: an open-source Java viewer for chemical structures in 3D.
- For Jmol Menu: Right click on the viewer.
- Note: Accept the security warning to view.
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1IF7 1.98 Å EC: 4.2.1.1 CARBONIC ANHYDRASE II COMPLEXED WITH (R)-N-(3-INDOL-1-YL-2- METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE HOMO SAPIENS CARBONIC ANHYDRASE II (R)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE LYASE
Ref.: COMBINATORIAL COMPUTATIONAL METHOD GIVES NEW PICOMOLAR LIGANDS FOR A KNOWN ENZYME. PROC.NATL.ACAD.SCI.USA V. 99 1270 2002
Members (228)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 12 families.
1 3K34 - SUA C13 H14 N2 O3 S3 c1cc(ccc1N....
2 2H15 Ki = 2135 nM B19 C12 H22 N2 O7 S CC1(O[C@@H....
3 3T82 Ki = 307 nM SG4 C10 H17 N O10 S CC(=O)O[C@....
4 1KWR ic50 = 0.25 uM SG2 C8 H8 N2 O3 S2 CN1c2ccc(c....
5 4HT0 Kd = 10 nM V50 C12 H9 F4 N3 O2 S2 Cc1cc(nc(n....
6 1OQ5 ic50 = 21 nM CEL C17 H14 F3 N3 O2 S Cc1ccc(cc1....
7 1IF8 Kd = 230 pM SBS C19 H21 N3 O3 S C[C@@H](CN....
8 2HL4 Ki = 23 nM BO1 C12 H18 N2 O7 S c1cc(ccc1N....
9 2OSM ic50 = 1.05 uM HTS C6 H6 O S c1ccc(c(c1....
10 3P58 Ki = 25.4 nM P58 C9 H11 N S2 CN(Cc1cccc....
11 1G53 Kd = 0.91 nM F6B C14 H12 F2 N2 O3 S c1cc(c(c(c....
12 4MTY - SBW C14 H14 N2 O4 S c1cc(cc(c1....
13 3BL0 Ki = 121 nM BL0 C5 H10 N4 O2 S2 CN(C)c1nnc....
14 2QOA Ki = 52 nM MAJ C9 H11 N O2 S c1cc2c(cc1....
15 1I9L Kd = 3.3 nM INV C14 H13 F N2 O3 S c1cc(ccc1C....
16 3SAX Kd = 0.14 uM E50 C14 H14 Cl N3 O3 S2 CCc1cnc(nc....
17 1BCD Kd = 2 nM FMS C H2 F3 N O2 S C(F)(F)(F)....
18 3VBD Ki = 8.6 nM 0FZ C16 H16 N2 O3 S COc1ccc2c(....
19 3M5E Kd = 0.043 uM JDR C13 H13 Cl N4 O3 S2 CSc1nc(c(c....
20 3RZ7 Kd = 1.1 nM RZ7 C13 H9 F11 N2 O3 S c1cc(ccc1C....
21 3P5A Ki = 0.95 nM IT2 C5 H9 N O S2 C1COCCN1C(....
22 3MHL Kd = 0.056 uM J71 C12 H13 N5 O5 S COc1c(c(nc....
23 2AW1 Ki = 43 nM COX C16 H14 N2 O3 S Cc1c(c(no1....
24 2FNN Ki = 200 mM 4MZ C4 H6 N2 Cc1c[nH]cn....
25 3P5L Ki = 40.8 nM IT5 C13 H14 N2 S2 c1ccc(cc1)....
26 2WD3 ic50 = 86 nM MS4 C16 H12 Cl N5 O3 S c1cc(c(cc1....
27 4M2W - ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
28 2POU Ki = 38 nM I7A C6 H6 Cl2 N2 O4 S2 c1c(cc(c(c....
29 4E3F Ki = 3 mM GRE C7 H6 O4 c1cc(c(c(c....
30 3NB5 Ki = 18 nM R21 C16 H17 Cl N2 O4 S c1cc(ccc1C....
31 2HOC Ki = 0.3 nM 1CN C8 H7 Cl F N5 O4 S3 c1c(cc(c(c....
32 1I9N Kd = 2.2 nM IOA C14 H12 F2 N2 O3 S c1cc(ccc1C....
33 3DD8 Ki = 14 nM 2C7 C16 H21 N O5 S2 c1cc2c(cc1....
34 3MHC Ki = 11 nM ARZ C13 H18 N4 O3 S2 C1C2CC3CC1....
35 2WEG Kd = 314 nM FBV C6 H6 F N O2 S c1ccc(c(c1....
36 3RZ0 Kd = 28 nM RZ0 C11 H16 N2 O3 S CCCCNC(=O)....
37 1CNY Kd = 14 nM EG3 C22 H30 N4 O6 S c1ccc(cc1)....
38 3MMF Ki = 37 nM D9H C11 H13 Cl N6 O3 S c1cc(ccc1N....
39 3M96 Kd = 0.06 uM E38 C15 H11 Br Cl N3 O3 S2 c1cc(c(cc1....
40 4ITP Ki = 54 nM 1GD C15 H16 N2 O3 S c1ccc(cc1)....
41 3SAP Kd = 0.014 uM E2I C16 H19 N3 O3 S2 CCCCc1cnc(....
42 2FOV Kd = 28 nM B30 C13 H15 Cu N3 O7 S c1cc(ccc1C....
43 2X7U Ki = 5340 nM WZA C19 H27 N O5 S C[C@]12CC[....
44 2NNS Kd = 0.9 uM M25 C10 H14 N2 O3 S CC(=O)NCCc....
45 2GD8 ic50 = 379 nM PO1 C19 H28 N2 O7 S2 C[C@]12CC[....
46 1BNV Kd = 1.7 nM AL7 C14 H17 N3 O5 S3 CN[C@@H]1C....
47 4JSZ Ki = 5000 uM FB2 C6 H7 N O2 S c1ccc(cc1)....
48 1I9Q Kd = 3.9 nM IOF C14 H11 F3 N2 O3 S c1cc(ccc1C....
49 2Q1Q Ki = 7 nM OSP C10 H14 N2 O4 S2 c1cc(ccc1N....
50 3FFP Ki = 72.5 nM LC1 C10 H8 N4 O2 S2 c1cc2c(cc1....
51 1G0E - 4MZ C4 H6 N2 Cc1c[nH]cn....
52 3R17 Ki = 390 nM 5UM C12 H11 F N2 O3 S2 c1cc(sc1)C....
53 2OSF ic50 ~ 148 uM TH0 C6 H6 O2 S c1cc(c(cc1....
54 2HD6 Ki = 16 nM BOS C13 H12 N2 O3 S2 c1ccc(c(c1....
55 2QO8 Ki = 3.4 nM 3CC C17 H26 N2 O3 S CCCC(CCC)C....
56 1I91 ic50 = 1.15 nM INQ C17 H19 N3 O6 S3 c1cc(cc(c1....
57 1BN1 Kd = 0.46 nM AL5 C12 H14 N2 O4 S3 Cc1ccc(cc1....
58 1G48 Kd = 3.9 nM F6B C14 H12 F2 N2 O3 S c1cc(c(c(c....
59 1G45 Kd = 2.3 nM FSB C14 H13 F N2 O3 S c1ccc(c(c1....
60 1AM6 ic50 = 47 uM HAE C2 H5 N O2 CC(=O)NO
61 2NNO Kd = 0.4 uM M28 C9 H11 N O4 S c1cc(ccc1C....
62 1OKL Kd = 0.93 uM MNS C12 H14 N2 O2 S CN(C)c1ccc....
63 3CA2 - AMS C6 H7 Hg N2 O2 S c1cc(c(cc1....
64 3OY0 Ki = 10.1 nM OY0 C15 H24 N2 O3 S CCC[C@H](C....
65 2FOS Kd = 27 nM B17 C17 H23 Cu N3 O9 S c1cc(ccc1C....
66 2EZ7 Kd = 43.5 uM DHI C6 H10 N3 O2 c1c([nH+]c....
67 3MZC Ki = 226 nM S6I C12 H17 N3 O3 S c1cc(ccc1N....
68 3M2N - J74 C12 H12 Cl N5 O4 S c1cc(ccc1C....
69 3OYS Ki = 9 nM OYS C14 H14 N2 O3 S c1ccc(cc1)....
70 1IF7 Kd = 30 pM SBR C19 H21 N3 O3 S C[C@H](CNC....
71 3RYZ Kd = 2.4 nM RYZ C11 H9 F7 N2 O3 S c1cc(ccc1C....
72 4M2V - BZ1 C12 H21 N3 O5 S3 CCN[C@H]1C....
73 3DCW Ki < 1 nM EZL C9 H10 N2 O3 S2 CCOc1ccc2c....
74 3S8X Kd = 0.07 uM E59 C13 H13 N3 O4 S2 CC1=CC(=O)....
75 3C7P ic50 = 0.1 nM POF C24 H27 N3 O5 S C[C@]12CC[....
76 3K7K Kd ~ 8.86 nM KCS C H2 S3 C(=S)(S)S
77 3T83 Ki = 105 nM MG5 C15 H25 N O11 S CCC(=O)O[C....
78 3BL1 Ki = 2520 nM BL1 C16 H16 Cl N3 O3 S C[C@H]1Cc2....
79 3MHO Kd = 0.32 uM J43 C12 H11 Cl N4 O3 S2 CSc1nc(c(c....
80 3DAZ Ki = 11.8 nM MZM C5 H9 N4 O3 S2 CC(=O)Nc1[....
81 3K2F Ki = 63 nM NKX C14 H20 N4 O12 S3 CCN([C@H]1....
82 2WEO Kd = 118 nM FBW C6 H6 F N O2 S c1cc(cc(c1....
83 1G54 Kd = 1.5 nM FFB C14 H9 F5 N2 O3 S c1cc(ccc1C....
84 3PO6 - DT9 C12 H18 N2 O4 S C[C@H]1c2c....
85 3V7X Ki = 2.7 nM D7A C17 H20 N2 O5 S COc1ccc(cc....
86 4JSS Ki = 500 uM BEW C5 H6 N O S c1cc[n+](c....
87 2Q38 Ki = 5950 nM LSA C7 H5 N O3 S c1ccc2c(c1....
88 3IBU Ki = 0.7 nM O48 C10 H23 N O3 S CCCCCCCCCC....
89 1BNT Kd = 0.16 nM AL2 C13 H14 N2 O6 S3 COc1ccc(cc....
90 3HS4 Ki = 10 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
91 2HKK Ka = 96 M^-1 ALE C9 H13 N O3 CNC[C@@H](....
92 3DCS Ki = 11.4 nM MZM C5 H9 N4 O3 S2 CC(=O)Nc1[....
93 2NNG Kd = 4.4 uM ZYX C8 H12 N2 O2 S c1cc(ccc1C....
94 3RYV Kd = 86 nM RYV C9 H12 N2 O3 S CCNC(=O)c1....
95 2WEJ Kd = 839 nM FB2 C6 H7 N O2 S c1ccc(cc1)....
96 3F8E Ki = 59 nM TE1 C15 H20 O5 CC(C)C[C@@....
97 3MYQ Kd = 0.03 uM E27 C18 H13 Cl N4 O3 S2 c1ccc2c(c1....
98 3DD0 Ki < 1 nM EZL C9 H10 N2 O3 S2 CCOc1ccc2c....
99 3ML2 Ki = 9.1 nM SU0 C18 H16 N2 O6 S COc1ccc2c(....
100 4M2R Ki = 3.2 nM BZ1 C12 H21 N3 O5 S3 CCN[C@H]1C....
101 4JSA Ki = 11 uM FB2 C6 H7 N O2 S c1ccc(cc1)....
102 3CYU Kd = 60 nM 0CR C74 H74 N10 O18 S COc1cc2c3c....
103 3V5G Ki = 74 nM 0F3 C6 H9 N3 O4 S2 c1cc(ccc1N....
104 1EOU ic50 = 36 nM SMS C9 H15 N O10 S2 CC1(O[C@H]....
105 1BN4 Kd = 0.49 nM AL9 C12 H14 N2 O5 S3 COc1ccc(cc....
106 1IF4 - FBS C6 H6 F N O2 S c1cc(ccc1F....
107 1BNW Kd = 0.83 nM TPD C9 H10 N2 O4 S4 c1cc(sc1)C....
108 2EU3 - FF3 C3 H4 F2 N4 O2 S2 c1(nnc(s1)....
109 2QP6 Ki = 58.9 nM MB1 C6 H5 Cl N2 O4 S c1cc(c(cc1....
110 1G4O Kd = 5.6 nM BSB C14 H14 N2 O3 S c1ccc(cc1)....
111 4MDM Ki = 6.79 uM 26E C3 H5 B9 N2 O2 S B123B45B16....
112 3RZ8 Kd = 6.7 nM RZ8 C13 H20 N2 O3 S CCCCCCNC(=....
113 3KIG ic50 = 245 nM DA4 C8 H7 N O2 S C#Cc1cccc(....
114 3EFT Ki = 12 nM 3BS C16 H25 Cl N4 O3 S2 CC1(CC(CC(....
115 3EFI - TRP C11 H12 N2 O2 O=C([O-])C....
116 3N0N Ki = 50 nM P9B C13 H8 F5 N3 O3 S c1cc(ccc1N....
117 1CIN Ki = 1.88 nM MTS C9 H14 N2 O4 S3 C[C@H]1C[C....
118 2X7T Ki = 232 nM WZB C20 H30 N2 O6 S2 CCc1cc2c(c....
119 3T5Z Ki = 8.96 uM B09 C7 H9 N O3 S CONS(=O)(=....
120 4FIK - TH0 C6 H6 O2 S c1cc(c(cc1....
121 4E3D Ki = 5 mM GTQ C7 H6 O4 c1cc(c(cc1....
122 2FMZ Ki = 35 nM DPN C9 H11 N O2 c1ccc(cc1)....
123 1G46 Kd = 1.6 nM F2B C14 H12 F2 N2 O3 S c1cc(c(c(c....
124 3IBL Ki = 14.6 nM O59 C8 H20 N2 O6 S2 C(CCCCOS(=....
125 3IEO Ki = 331 nM AMJ C13 H18 N2 O3 CC(=O)N[C@....
126 3F4X Ki = 138 nM KLT C14 H11 Cl N2 O4 S c1ccc2c(c1....
127 3T5U Ki = 5.47 uM A09 C6 H7 N O3 S c1ccc(cc1)....
128 1BNU Kd = 0.2 nM AL3 C11 H12 N2 O5 S4 c1cc(sc1)C....
129 1OKN Kd = 2.3 nM STB C12 H19 N3 O3 S2 c1cc(ccc1C....
130 1IF6 - FBU C6 H5 F2 N O2 S c1c(cc(cc1....
131 2O4Z Ki = 566 nM HSW H4 N2 O3 S NS(=O)(=O)....
132 3T84 Ki = 106 nM SG6 C8 H15 N O9 S CC(=O)O[C@....
133 3DBU Ki = 8.8 nM D8W C8 H8 N4 O4 S3 c1ccc(cc1)....
134 4MO8 Ki = 10.1 nM 2VQ C6 H11 N5 O4 S Cc1ncc(n1C....
135 2WD2 - MS5 C18 H22 N2 O5 S COc1cccc(c....
136 1CRA - TRI C2 H3 N3 c1[nH]cnn1
137 1I9P Kd = 3.9 nM IOE C14 H11 F3 N2 O3 S c1cc(ccc1C....
138 3N2P Ki = 15 nM AYX C13 H12 N4 O5 S c1cc(cc(c1....
139 3M40 Kd = 0.17 uM J45 C10 H8 Cl N5 O4 S c1cc(ccc1N....
140 2FOU Kd = 80 nM B22 C21 H22 Cu N4 O8 S c1cc(cc(c1....
141 4KNJ Kd = 11.1 nM E1F C12 H10 Cl N3 O3 S2 c1cnc(nc1)....
142 1OKM - SAB C11 H17 N3 O3 S c1cc(ccc1C....
143 3RZ5 Kd = 13 nM RZ5 C12 H18 N2 O3 S CCCCCNC(=O....
144 3N4B Ki = 96 nM WWZ C13 H12 F N3 O3 S c1cc(ccc1N....
145 3M1K Ki = 4.1 uM BEW C5 H6 N O S c1cc[n+](c....
146 1CIM Ki = 1.52 nM PTS C8 H12 N2 O4 S3 C[C@H]1C[C....
147 3HKN Ki = 4.51 uM MFS C26 H37 N O19 S CC(=O)OC[C....
148 1BN3 Kd = 0.13 nM AL6 C13 H12 N2 O5 S3 COc1cccc(c....
149 2GEH Ki = 28 uM NHY C H4 N2 O2 C(=O)(N)NO
150 4E49 Ki = 7.7 uM RCO C6 H6 O2 c1cc(cc(c1....
151 4MDG Ki = 0.7 uM 25X C3 H5 B10 N2 O2 S B1234B567B....
152 3M3X Kd = 0.15 uM JS7 C13 H15 N5 O5 S COc1c(c(nc....
153 3B4F Ki = 7.2 nM TUO C15 H14 N4 O3 S c1ccc(cc1)....
154 4E3G Ki = 8 mM PHB C7 H6 O3 c1cc(ccc1C....
155 4M2U Ki = 9.1 nM ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
156 4MDL Ki = 1.16 uM 25Y C3 H5 B10 N2 O2 S B1234B567B....
157 3MNU Ki = 48 nM BON C12 H19 B N2 O4 S B1(OC(C(O1....
158 2ABE Ki = 113 uM HIS C6 H10 N3 O2 c1c([nH+]c....
159 3RYY Kd = 38 nM RYY C10 H14 N2 O3 S CCCNC(=O)c....
160 3SBI Kd = 0.017 uM E90 C12 H11 N3 O3 S2 c1cnc(nc1)....
161 1BNQ Kd = 0.32 nM AL4 C11 H19 N3 O5 S3 CCN[C@H]1C....
162 1XPZ Kd = 84 nM 4TZ C16 H14 N6 O3 S c1cc(ccc1C....
163 3RZ1 Kd = 1.8 nM RZ1 C12 H9 F9 N2 O3 S c1cc(ccc1C....
164 1YDB Kd = 5.8 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
165 2EU2 - 5DS C5 H11 N5 O2 S2 CN(C)c1nnc....
166 1MOO - 4MZ C4 H6 N2 Cc1c[nH]cn....
167 2NNV Kd = 0.03 uM M29 C11 H15 N O4 S CCOC(=O)CC....
168 3DC3 Ki = 4.9 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
169 3MNA Ki = 41 nM DWH C12 H13 Cl N6 O4 S COC(=O)CNc....
170 1CNW Kd = 19 nM EG1 C15 H24 N4 O6 S c1cc(ccc1C....
171 1G1D Kd = 0.36 nM FSB C14 H13 F N2 O3 S c1ccc(c(c1....
172 3N3J Ki = 3.3 nM WWV C16 H19 N3 O3 S CC(C)c1ccc....
173 3CAJ Ki = 8 nM EZL C9 H10 N2 O3 S2 CCOc1ccc2c....
174 2HNC Ki = 60 nM 1SA C2 H4 N4 O2 S2 c1(nnc(s1)....
175 3NI5 Ki = 28 nM C1H C13 H15 N5 O9 S3 c1cc(cc(c1....
176 3S9T Kd = 0.22 uM E49 C14 H14 Cl N3 O3 S2 Cc1cc(nc(n....
177 3SBH Kd = 0.033 uM E65 C14 H15 N3 O3 S2 Cc1cc(nc(n....
178 4ILX Ki = 233 nM 1EZ C18 H24 N2 O3 S c1cc(ccc1N....
179 3D9Z Ki = 2 nM D9Z C8 H6 Cl N3 O2 S2 c1ccc(c(c1....
180 3P4V Ki = 8 uM PMX C14 H14 Cl N O6 COC(=O)/C=....
181 1G52 Kd = 0.29 nM F2B C14 H12 F2 N2 O3 S c1cc(c(c(c....
182 3IBI Ki = 2.6 nM BOW C8 H19 N O3 S CCCCCCCCOS....
183 2H4N Ki = 2 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
184 1I9O Kd = 3.8 nM IOC C14 H11 F3 N2 O3 S c1cc(ccc1C....
185 1YDD Kd = 86 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
186 2POV Ki = 75 nM I7B C6 H8 Cl N3 O4 S2 c1c(c(cc(c....
187 1G4J Kd = 2 nM FFB C14 H9 F5 N2 O3 S c1cc(ccc1C....
188 3D8W Ki = 7 nM D8W C8 H8 N4 O4 S3 c1ccc(cc1)....
189 2WEH Kd = 1125 nM FB1 C6 H6 Cl N O2 S c1ccc(c(c1....
190 1ZSB Kd = 250 mM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
191 3OYQ Ki = 10.3 nM OYQ C13 H20 N2 O3 S CC[C@H](C)....
192 3T85 Ki = 11.3 nM SG7 C10 H17 N O10 S CC(=O)O[C@....
193 3M67 Kd = 0.18 uM E36 C17 H14 Cl N3 O5 S2 c1cc(c(cc1....
194 1IF5 - FBT C6 H5 F2 N O2 S c1cc(c(c(c....
195 1I9M Kd = 3.3 nM INW C14 H12 F2 N2 O3 S c1cc(ccc1C....
196 2X7S Ki = 1660 nM WZC C19 H27 N O5 S C[C@]12CC[....
197 3IBN Ki = 24.5 nM O60 C10 H24 N2 O6 S2 C(CCCCCOS(....
198 4KAP - 1QV C7 H2 F4 N2 O2 S2 c12c(c(c(c....
199 2FMG - PHE C9 H11 N O2 O=C([O-])C....
200 1TTM Kd ~ 45 nM 667 C14 H15 N O5 S c1cc2c(cc1....
201 3MHM Kd = 0.1 uM J75 C18 H18 N6 O4 S c1ccc(cc1)....
202 2POW Ki = 63 nM I7C C7 H8 F3 N3 O4 S2 c1c(c(cc(c....
203 1AVN Kd = 0.125 mM HSM C5 H9 N3 c1c(nc[nH]....
204 1I90 ic50 = 1.28 nM INM C10 H15 N3 O5 S3 COCCC[N@]1....
205 1LUG - SUA C13 H14 N2 O3 S3 c1cc(ccc1N....
206 4E4A Ki = 9 mM JKE C7 H6 O2 S c1ccc(c(c1....
207 4IWZ Ki = 51 nM 1GO C8 H8 N4 O3 S3 c1cc(sc1)C....
208 1ZE8 Ki = 21 nM PIU C16 H21 N2 O2 S Cc1cc([n+]....
209 4E3H Ki = 90 nM HQE C6 H6 O2 c1cc(ccc1O....
210 1I8Z ic50 = 1.27 nM INL C18 H21 N3 O6 S3 COc1cccc(c....
211 1BNN Kd = 0.1 nM AL1 C13 H14 N2 O5 S3 COc1cccc(c....
212 1XQ0 Kd = 454 nM 4TR C16 H13 Br N6 O3 S c1cc(ccc1C....
213 2Q1B Ki = 5950 nM LSA C7 H5 N O3 S c1ccc2c(c1....
214 3BET ic50 = 1.5 uM CTF C21 H28 N2 O4 S C[C@]12CC[....
215 2F14 Ki = 45 nM FL1 C29 H23 N3 O7 S2 c1cc(ccc1C....
216 3R16 Ki = 50 nM 5UN C12 H12 N2 O3 S2 c1cc(sc1)C....
217 1CIL Ki = 0.372 nM ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
218 3MHI Kd = 0.2 uM J90 C11 H11 N5 O5 S c1cc(ccc1C....
219 3DCC Ki = 1.1 nM D9Z C8 H6 Cl N3 O2 S2 c1ccc(c(c1....
220 4KNI Kd = 16.7 nM E1E C14 H14 Cl N3 O3 S2 Cc1cc(nc(n....
221 1YDA Kd = 280 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
222 3IGP ic50 = 94.5 nM DT7 C11 H16 N2 O4 S COc1cc2c(c....
223 3RYJ Kd = 16 nM RYJ C9 H9 F3 N2 O3 S c1cc(ccc1C....
224 1CNX Kd = 43 nM EG2 C13 H21 N3 O5 S c1cc(ccc1C....
225 2FOQ Kd = 235 nM B15 C20 H21 Cu N3 O7 S c1cc(ccc1C....
226 4BCW - TU0 C8 H7 Br O4 S c1cc(c(cc1....
227 3RYX Kd = 7.3 nM RYX C10 H9 F5 N2 O3 S c1cc(ccc1C....
228 1IF9 - SBB C19 H21 N3 O3 S CC[C@H](CN....