Receptor
PDB id Resolution Class Description Source Keywords
1a4r 2.5 Å EC: 3.-.-.- G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM HOMO SAPIENS HYDROLASE GTPASE SIGNAL TRANSDUCTION
Ref.: NUCLEOTIDE BINDING TO THE G12V-MUTANT OF CDC42 INVESTIGATED BY X-RAY DIFFRACTION AND FLUORESCENCE SPECTROSCOPY: TWO DIFFERENT NUCLEOTIDE STATES IN ONE CRYSTAL. PROTEIN SCI. V. 8 778 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data Chemaxon Viewer Molecular Weight (Da) Formula SMILES
GDP A:200;
Valid;
none;
Kd = 9.4 pM
443.201 C10 H15 N5 O11 P2 c1nc2...
GNH B:400;
Valid;
none;
Kd = 0.22 uM
442.216 C10 H16 N6 O10 P2 c1nc2...
MG A:199;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1A4R 2.5 Å EC: 3.-.-.- G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM HOMO SAPIENS HYDROLASE GTPASE SIGNAL TRANSDUCTION
Ref.: NUCLEOTIDE BINDING TO THE G12V-MUTANT OF CDC42 INVESTIGATED BY X-RAY DIFFRACTION AND FLUORESCENCE SPECTROSCOPY: TWO DIFFERENT NUCLEOTIDE STATES IN ONE CRYSTAL. PROTEIN SCI. V. 8 778 1999
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 194 families.
1 2QRZ - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
2 1A4R Kd = 9.4 pM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (13)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 172 families.
1 2W2T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1MH1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 3SBD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 2P2L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 2W2V - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
6 1RYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 1RYH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 3TH5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 2QRZ - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
10 1A4R Kd = 9.4 pM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 4U5X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 2GCN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 1GWN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (211)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 123 families.
1 1M7B - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 1G17 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 1G16 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1Z2A - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1Z22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 1N6N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 1HUQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 1Z07 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 1N6R - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 1N6I - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 1Z0D - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 1R2Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 1N6H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
14 1N6L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
15 1N6P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
16 1N6K - GDP AF3 n/a n/a
17 1N6O - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
18 1TU4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
19 4DKX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
20 2Y8E - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
21 2A5J - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
22 4LHW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
23 4LHV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
24 3SBD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
25 2P2L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
26 2W2V - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
27 4LYJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
28 4Q01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
29 1RVD - DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
30 4M21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
31 2RGA - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
32 821P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
33 1Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
34 3RS7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
35 2CLC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
36 4EPT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
37 4EPY Kd = 340 uM 0QY C21 H21 N5 O c1ccc2c(c1....
38 6Q21 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
39 4L9W - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
40 4DLZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
41 1AGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
42 3V4F - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
43 1GNQ - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
44 3K9N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
45 2Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
46 3RS2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
47 4M1T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
48 4L9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
49 4M1S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50 4EPV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
51 2QUZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
52 1CLU Kd = 5.4 nM DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
53 4L8G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
54 3K8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
55 3OIV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
56 2RGD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
57 4PZY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
58 4LPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
59 4DLV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
60 4Q02 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
61 4LRW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
62 3LBI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
63 2CLD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
64 3RSL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
65 4M1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
66 3L8Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
67 3LBH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
68 721P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
69 1LF5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70 1GNR - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
71 4LUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
72 2RGE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
73 1LF0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
74 4DLS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
75 4M22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
76 1XCM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
77 421P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
78 4DLR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
79 4DLY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
80 2CE2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
81 1ZW6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
82 4Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
83 4DLU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
84 1CTQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
85 2RGC - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
86 3OIU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
87 2CL0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
88 3RS5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
89 3RRZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
90 4EPW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
91 1IOZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
92 2EVW - XY2 C12 H15 N5 O4 CC(=O)N(C)....
93 221P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
94 4LYH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
95 4DLX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
96 2RGB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
97 4Q03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
98 4LDJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
99 4PZZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
100 1XJ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
101 1ZVQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
102 3KKM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
103 1JAI - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
104 1P2S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
105 3L8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
106 621P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
107 1P2V - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
108 3RS4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
109 2CL7 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
110 3LBN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
111 4NMM - Y9Z C14 H22 N6 O12 P2 CC(=O)NCCO....
112 3OIW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
113 3RSO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
114 4LV6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
115 5P21 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
116 4EPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
117 4DLT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
118 1P2U - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
119 4EPR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
120 4DLW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
121 3RS0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
122 3KKN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
123 4M1O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
124 4M1Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
125 3I3S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
126 2RGG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
127 4OBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
128 3RRY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
129 4LYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
130 1JAH - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
131 1QRA - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
132 1U8Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
133 1U90 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
134 1U8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
135 3RS3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
136 2CL6 - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
137 121P - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
138 3TGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
139 1P2T - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
140 1YU9 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
141 2BMD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
142 2BME - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
143 1YZU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
144 1Z08 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
145 1Z0I - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
146 1YZT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
147 1YZN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
148 3RWM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
149 3RWO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
150 3REG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
151 2F9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
152 2F9M - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
153 1YZK - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
154 1YVD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
155 1Z06 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
156 3Q7P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
157 2DPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
158 3Q7Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
159 3Q72 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
160 2WKQ - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
161 1RYH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
162 2FE4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
163 2FFQ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
164 2E9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
165 3NKV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
166 1EK0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
167 1S8F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
168 1YZL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
169 1WMS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
170 1D5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
171 1Z0F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
172 1OIX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
173 1OIW - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
174 1OIV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
175 1A4R Kd = 9.4 pM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
176 3E5H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
177 4DSU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
178 4DSN - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
179 4DST - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
180 4DSO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
181 1KAO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
182 3RAP - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
183 1KMQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
184 1A2B - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
185 1DPF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
186 1FTN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
187 1YZQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
188 2GIL - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
189 4U5X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
190 1Z0A - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
191 3Q85 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
192 2HT6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
193 1KY3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
194 1KY2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
195 1VG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
196 3KKO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
197 3KKP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
198 1X1R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
199 3KKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
200 1X1S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
201 1T91 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
202 1VG8 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
203 3RAB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
204 2GCN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
205 1GWN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
206 2EW1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
207 4O25 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
208 4O2R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
209 1XTQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
210 4O2L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
211 3SEA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 139
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDD 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDC 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 GTP MG 0.724138 0.923077
25 BEF GDP 0.724138 0.888889
26 G5P 0.723404 0.973684
27 GTG 0.72043 0.936709
28 GFB 0.72043 0.961039
29 GDR 0.72043 0.961039
30 G4P 0.715909 0.986486
31 GCP G 0.715909 0.935065
32 G3A 0.712766 0.973684
33 GDP ALF 0.7 0.888889
34 GDP AF3 0.7 0.888889
35 YGP 0.698925 0.901235
36 JB2 0.697917 0.961039
37 GKD 0.697917 0.961039
38 GPD 0.690722 0.925
39 GDX 0.690722 0.973684
40 GMP 0.684211 0.88
41 0O2 0.666667 0.986486
42 JB3 0.656863 0.948718
43 NGD 0.650485 0.961039
44 GDP 7MG 0.636364 0.911392
45 DGI 0.636364 0.923077
46 U2G 0.634615 0.936709
47 GPX 0.634409 0.946667
48 G G 0.632653 0.948052
49 IDP 0.632184 0.972973
50 2MD 0.632075 0.891566
51 CAG 0.62963 0.880952
52 CG2 0.622642 0.936709
53 FEG 0.619048 0.879518
54 MGD 0.614679 0.891566
55 3GP 0.611765 0.946667
56 MD1 0.607143 0.891566
57 PGD 0.59292 0.925
58 DGT 0.591398 0.923077
59 BGO 0.588785 0.924051
60 TPG 0.582609 0.840909
61 DBG 0.582609 0.948718
62 2GP 0.574713 0.96
63 FE9 0.570175 0.776596
64 I2C FE2 CMO CMO 0.566372 0.808989
65 G A A A 0.553571 0.923077
66 MGP 0.553191 0.961039
67 G4M 0.548387 0.880952
68 G1R G1R 0.542373 0.924051
69 P2G 0.527473 0.883117
70 PGD O 0.525 0.850575
71 ADP 0.522222 0.92
72 GGM 0.517544 0.901235
73 DGP 0.516484 0.910256
74 DG 0.516484 0.910256
75 P1G 0.516129 0.871795
76 G G U 0.509259 0.935065
77 G1G 0.508475 0.925
78 IMP 0.505495 0.959459
79 G C 0.504348 0.9
80 GPC 0.491525 0.879518
81 G7M 0.483871 0.948052
82 6AD 0.479592 0.841463
83 ATP 0.473684 0.92
84 G2Q 0.471154 0.961039
85 U G A 0.469697 0.888889
86 AQP 0.46875 0.92
87 5FA 0.46875 0.92
88 GTA 0.468468 0.936709
89 G G G RPC 0.466102 0.875
90 SGP 0.463158 0.82716
91 01G 0.462963 0.902439
92 AP5 0.457447 0.894737
93 B4P 0.457447 0.894737
94 A2D 0.456522 0.894737
95 G G G C 0.455285 0.9125
96 ANP 0.454545 0.896104
97 5GP 5GP 0.454545 0.883117
98 ACQ 0.454545 0.896104
99 G U34 0.449153 0.888889
100 DG DG 0.448598 0.865854
101 ITT 0.447917 0.868421
102 BA3 0.446809 0.894737
103 35G 0.444444 0.933333
104 PCG 0.444444 0.933333
105 C2E 0.444444 0.921053
106 MGO 0.441176 0.864198
107 G C C C 0.4375 0.924051
108 M33 0.43299 0.883117
109 ACP 0.428571 0.896104
110 MGQ 0.424528 0.935897
111 AR6 0.424242 0.894737
112 APR 0.424242 0.894737
113 93A 0.42268 0.833333
114 A4P 0.420168 0.869048
115 SAP 0.42 0.873418
116 AD9 0.42 0.896104
117 AGS 0.42 0.873418
118 CA0 0.418367 0.896104
119 ATF 0.417476 0.884615
120 AGO 0.414634 0.888889
121 NIA 0.413043 0.82716
122 MGV 0.412844 0.890244
123 TAT 0.411765 0.884615
124 A1R 0.411215 0.839506
125 ADQ 0.411215 0.871795
126 RGT 0.410714 0.909091
127 CGP 0.409836 0.86747
128 A 0.408602 0.893333
129 AMP 0.408602 0.893333
130 UP5 0.40678 0.873418
131 AMZ 0.406593 0.918919
132 C2R 0.406593 0.906667
133 JBT 0.405882 0.778947
134 A22 0.40566 0.907895
135 25L 0.405405 0.907895
136 ADX 0.40404 0.809524
137 8OD 0.401961 0.946667
138 4TC 0.4 0.851852
139 50T 0.4 0.883117
Ligand no: 2; Ligand: GNH; Similar ligands found: 127
No: Ligand ECFP6 Tc MDL keys Tc
1 GNH 1 1
2 GP3 0.87013 0.961039
3 GDP 0.858974 0.986667
4 GSP 0.829268 0.936709
5 GTP 0.82716 0.986667
6 GCP 0.817073 0.961039
7 G1R 0.817073 0.973684
8 GNP 0.807229 0.986842
9 5GP 0.794872 0.973333
10 G 0.794872 0.973333
11 GMV 0.783133 0.961039
12 G2R 0.761364 0.948718
13 GP2 0.746988 0.948718
14 GDC 0.73913 0.948718
15 GDD 0.73913 0.948718
16 GKE 0.73913 0.948718
17 GPG 0.733333 0.948718
18 GDP MG 0.729412 0.911392
19 GAV 0.727273 0.948718
20 G2P 0.724138 0.948718
21 Y9Z 0.72043 0.891566
22 GTG 0.712766 0.925
23 GFB 0.712766 0.948718
24 GDR 0.712766 0.948718
25 G3A 0.705263 0.961039
26 ALF 5GP 0.701149 0.878049
27 G5P 0.697917 0.961039
28 GTP MG 0.696629 0.911392
29 BEF GDP 0.696629 0.878049
30 YGP 0.691489 0.890244
31 JB2 0.690722 0.948718
32 GKD 0.690722 0.948718
33 GCP G 0.688889 0.923077
34 GPD 0.683673 0.91358
35 GDX 0.683673 0.961039
36 GMP 0.675325 0.868421
37 GDP AF3 0.673913 0.878049
38 GDP ALF 0.673913 0.878049
39 JB3 0.650485 0.936709
40 G3D 0.648352 0.973333
41 NGD 0.644231 0.948718
42 G4P 0.634409 0.973333
43 U2G 0.628571 0.925
44 FEG 0.628571 0.869048
45 G G 0.626263 0.935897
46 2MD 0.626168 0.880952
47 0O2 0.625 0.973333
48 MGD 0.623853 0.880952
49 CG2 0.616822 0.925
50 GDP 7MG 0.613861 0.9
51 CAG 0.609091 0.892857
52 3GP 0.604651 0.934211
53 PGD 0.60177 0.91358
54 MD1 0.587719 0.880952
55 TPG 0.577586 0.831461
56 DBG 0.577586 0.961538
57 2GP 0.568182 0.947368
58 FE9 0.565217 0.787234
59 GPX 0.545455 0.934211
60 DGI 0.542553 0.911392
61 IDP 0.537634 0.96
62 DGT 0.536082 0.911392
63 G A A A 0.535088 0.911392
64 I2C FE2 CMO CMO 0.534483 0.820225
65 PGD O 0.533333 0.840909
66 G4M 0.531746 0.870588
67 BGO 0.526786 0.9125
68 G1R G1R 0.525 0.9125
69 P2G 0.521739 0.871795
70 G1G 0.516949 0.91358
71 GGM 0.513043 0.91358
72 G G U 0.504587 0.923077
73 GPC 0.5 0.869048
74 MGP 0.5 0.948718
75 P1G 0.494737 0.860759
76 DGP 0.494624 0.898734
77 DG 0.494624 0.898734
78 G C 0.487179 0.888889
79 IMP 0.483871 0.946667
80 G2Q 0.466667 0.948718
81 GTA 0.464286 0.925
82 G7M 0.463158 0.935897
83 G G G RPC 0.462185 0.864198
84 U G A 0.455224 0.878049
85 G G G C 0.451613 0.901235
86 A2D 0.451613 0.883117
87 SGP 0.443299 0.817073
88 BA3 0.442105 0.883117
89 PCG 0.44 0.921053
90 35G 0.44 0.921053
91 C2E 0.44 0.909091
92 AP5 0.4375 0.883117
93 B4P 0.4375 0.883117
94 ADP 0.4375 0.907895
95 ANP 0.435644 0.909091
96 5GP 5GP 0.435644 0.871795
97 G C C C 0.434109 0.9125
98 G U34 0.433333 0.878049
99 SAP 0.43 0.8625
100 AGS 0.43 0.8625
101 M33 0.428571 0.871795
102 ATP 0.424242 0.907895
103 ACP 0.424242 0.884615
104 ACQ 0.421569 0.884615
105 A1R 0.420561 0.829268
106 AR6 0.42 0.883117
107 5FA 0.42 0.907895
108 APR 0.42 0.883117
109 AQP 0.42 0.907895
110 01G 0.419643 0.891566
111 DG DG 0.418182 0.855422
112 AD9 0.415842 0.884615
113 CA0 0.414141 0.884615
114 ATF 0.413462 0.873418
115 MGO 0.409524 0.853659
116 MGQ 0.407407 0.924051
117 ADQ 0.407407 0.860759
118 A4P 0.404959 0.858824
119 93A 0.40404 0.845238
120 6AD 0.403846 0.831325
121 5AL 0.403846 0.871795
122 C2R 0.402174 0.894737
123 AMZ 0.402174 0.906667
124 A22 0.401869 0.896104
125 ADX 0.4 0.8
126 ITT 0.4 0.857143
127 AGO 0.4 0.901235
Similar Binding Sites
Pocket no: 1; Query (leader) PDB : 1A4R; Ligand: GDP; Similar sites found: 504
This union binding pocket (no: 1) in the query (biounit: 1a4r.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1A4R GDP 1.305e-16 1
2 1A4R GNH 2.442e-15 0.9447
3 1MH1 GNP 1.163e-11 0.80452
4 1Z0K GTP 1.347e-11 0.79413
5 2WKQ GTP 1.294e-11 0.79089
6 1E96 GTP 1.737e-11 0.78923
7 3QBT GNP 2.002e-11 0.78253
8 1DS6 GDP 1.39e-13 0.78111
9 2GCO GNP 5.482e-12 0.78108
10 1TX4 ALF 2.864e-11 0.77959
11 1RYH GNP 1.675e-13 0.77807
12 2GCN GDP 2.248e-11 0.77616
13 3NKV GNP 5.79e-11 0.77325
14 1R2Q GNP 6.066e-11 0.77234
15 4DID GDP 2.717e-13 0.77108
16 1S8F GDP 6.473e-11 0.77107
17 1NF3 GNP 3.765e-11 0.76206
18 1CLU DBG 3.526e-10 0.76085
19 4ITR GDP 1.749e-12 0.75955
20 3TH5 GNP 1.984e-11 0.75709
21 1HE1 GDP 5.783e-11 0.75394
22 2FJU GSP 5.875e-11 0.75364
23 2W2X GSP 2.496e-11 0.75323
24 2J0V GDP 8.911e-13 0.75285
25 4U5X GNP 2.678e-11 0.75244
26 1GRN GDP 3.04e-12 0.75136
27 3LXR GDP 3.807e-12 0.74932
28 4DSU GDP 2.074e-10 0.74839
29 3REF GDP 9.98e-11 0.74361
30 3TKL GTP 1.87e-10 0.74342
31 2BME GNP 1.554e-10 0.74325
32 2UZI GTP 2.93e-10 0.74166
33 2NGR GDP 1.719e-12 0.74002
34 1UAD GNP 2.625e-10 0.73689
35 4LHW GNP 3.172e-10 0.73675
36 1NVU GTP 3.794e-10 0.73662
37 2FFQ GSP 5.319e-10 0.73628
38 2EW1 GNP 1.866e-10 0.73586
39 1Z06 GNP 1.906e-10 0.73545
40 1CXZ GSP 9.113e-11 0.7299
41 3MJH GTP 3.811e-10 0.72971
42 4HDQ GNP 5.628e-10 0.72894
43 1M7B GTP 9.586e-11 0.72867
44 2CL6 CAG 8.042e-10 0.72815
45 2BCG GDP 2.373e-10 0.72722
46 1YZK GNP 4.622e-10 0.72599
47 4C4P GNP 5.97e-10 0.72449
48 1KMQ GNP 3.873e-10 0.72194
49 4K81 GTP 4.875e-10 0.72134
50 4HAT GNP 1.061e-09 0.71969
51 1OIX GDP 7.729e-10 0.71948
52 3RAB GNP 8.272e-10 0.71817
53 1ZC3 GNP 1.242e-09 0.71661
54 1YVD GNP 6.37e-10 0.71622
55 4KVG GTP 6.457e-10 0.71596
56 4LX0 BEF 7.806e-10 0.71588
57 1NVV GNP 1.142e-09 0.71516
58 2G77 GDP 9.011e-11 0.7145
59 1GWN GTP 2.136e-10 0.71436
60 2A5J GDP 8.854e-11 0.71389
61 3TNF GNP 1.069e-09 0.71319
62 1YZN GNP 8.992e-10 0.71316
63 3M1I GTP 1.553e-09 0.71224
64 1XTQ GDP 7.951e-10 0.71197
65 2D7C GTP 9.73e-10 0.71164
66 2C5L GTP 1.037e-09 0.71041
67 1X1R GDP 1.45e-09 0.7073
68 4HDO GNP 1.45e-09 0.7073
69 1LFD GNP 1.11e-09 0.70558
70 1Z0J GTP 1.424e-09 0.70429
71 3BC1 GNP 1.716e-09 0.70403
72 1I4D GDP 1.204e-12 0.70031
73 2FH5 GTP 1.235e-09 0.69986
74 1Z0A GDP 8.522e-11 0.69958
75 1KSH GDP 1.066e-09 0.69879
76 4TMZ GSP 2.163e-09 0.69624
77 2A9K GDP 5.73e-10 0.69561
78 1GUA GNP 2.69e-09 0.69532
79 3T5G GDP 1.095e-10 0.69346
80 3KUD GDP 1.425e-09 0.6933
81 4D0N GDP 9.019e-12 0.69234
82 1U8Z GDP 2.8e-09 0.69126
83 1YZQ GNP 3.45e-09 0.69049
84 2Y8E GNP 3.177e-09 0.68883
85 2F9L GDP 2.735e-09 0.6883
86 1VG0 GDP 1.546e-10 0.68813
87 1WA5 GTP 7.24e-09 0.68762
88 1Z08 GNP 4.694e-09 0.68761
89 1KY3 GDP 1.587e-10 0.68737
90 1TU3 GNP 3.904e-09 0.68486
91 3SFV GDP 2.721e-09 0.68481
92 1G16 GDP 2.443e-09 0.68309
93 1VG8 GNP 4.289e-09 0.68304
94 1IBR GNP 5.986e-09 0.68288
95 3RWO GDP 7.302e-09 0.68193
96 4NON GDP 5.459e-09 0.6816
97 3BH7 ALF 7.753e-09 0.68075
98 1VG9 GDP 6.086e-10 0.68053
99 1KAO GDP 6.79e-09 0.68042
100 2EFE GNH 1.429e-09 0.68017
101 3WYG GTP 7.538e-09 0.67839
102 2CJW GDP 3.347e-11 0.67319
103 1VG1 GDP 2.017e-10 0.66841
104 3DOE GTP 5.4e-09 0.66808
105 3CPJ GDP 1.449e-09 0.66545
106 4NCN GTP 9.613e-09 0.66421
107 3WYF GTP 1.638e-08 0.66327
108 1Z0F GDP 2.6e-10 0.66323
109 4GOJ GNP 8.711e-09 0.65903
110 3GJX GTP 1.82e-08 0.65826
111 1OW3 GDP 1.1e-10 0.65556
112 1Z2A GDP 1.514e-08 0.6555
113 1EK0 GNP 1.687e-08 0.65343
114 1D5C GDP 3.583e-09 0.64933
115 1ZD9 GDP 8.042e-09 0.64824
116 3VMF GTP 2.785e-08 0.64699
117 2C78 GNP 1.75e-08 0.64583
118 3Q85 GNP 2.917e-10 0.64384
119 3Q72 GNP 3.273e-10 0.64212
120 1G4U GDP 6.898e-10 0.64037
121 1J2J GTP 1.373e-08 0.63854
122 4DKX GDP 1.15e-09 0.63819
123 1O3Y GTP 3.973e-08 0.63701
124 4M9Q GNP 2.969e-08 0.63583
125 3GJ0 GDP 3.835e-09 0.6352
126 1YRB GDP 6.31e-10 0.6319
127 2W83 GTP 3.769e-08 0.63131
128 2GJ8 ALF 9.197e-08 0.62965
129 3WY9 GDP 7.829e-10 0.62896
130 2HCJ GDP 8.834e-10 0.62713
131 3GJ7 GDP 2.639e-09 0.62631
132 2BVN GNP 7.469e-09 0.62538
133 1R4A GNP 5.17e-08 0.62533
134 3WYA GDP 1.097e-09 0.62447
135 3A1S GDP 4.217e-09 0.62384
136 3GJ5 GDP 3.327e-09 0.62299
137 3U6K GDP 3.278e-09 0.62293
138 1UPT GTP 3.358e-08 0.62249
139 3GJ8 GDP 3.488e-09 0.62216
140 2C77 GNP 6.612e-08 0.62067
141 3PCR GTP 9.351e-08 0.62061
142 4DCT GDP 2.719e-07 0.62047
143 4KAX GTP 6.826e-08 0.62007
144 3WXM GTP 8.155e-08 0.62005
145 4G5G GDP 3.84e-09 0.61989
146 4B47 GDP 1.857e-09 0.6185
147 3GJ3 GDP 4.697e-09 0.61846
148 1D8T GDP 4.737e-09 0.61718
149 3GJ4 GDP 4.995e-09 0.61659
150 3U6B GDP 1.955e-09 0.61646
151 2A5F GTP 8.356e-08 0.61624
152 2X77 GDP 2.315e-09 0.61403
153 1TQ4 GDP 2.81e-08 0.61286
154 2RCN GDP 2.06e-09 0.61177
155 4P3Y GDP 3.258e-09 0.60957
156 1WQ1 GDP 7.204e-08 0.6072
157 1MKY GDP 9.902e-10 0.60677
158 1M2O GNP 2.011e-07 0.60594
159 2QTV GNP 2.018e-07 0.60587
160 3N5C GDP 1.513e-08 0.60124
161 4J0Q GDP 6.528e-09 0.59856
162 3CX8 GSP 5.563e-07 0.59708
163 1WF3 GNP 2.88e-07 0.59601
164 1FZQ GDP 8.638e-09 0.59521
165 2QN6 GDP 2.879e-09 0.59421
166 1NRJ GTP 2.714e-07 0.59395
167 1G7S GDP 9.206e-09 0.59366
168 1SVI GDP 2.747e-09 0.59361
169 4BAS GNP 1.686e-07 0.59316
170 2HT6 GDP 3.331e-09 0.59305
171 2J59 GTP 1.781e-07 0.59238
172 1TAD ALF 9.301e-07 0.59164
173 2XTZ GSP 4.311e-07 0.59132
174 1SVK ALF 1.036e-06 0.58952
175 1TAD ALF 1.074e-06 0.58879
176 2ODE ALF 9.588e-07 0.58877
177 2WJH GDP 1.852e-08 0.58763
178 1ZJ6 G3D 1.561e-08 0.5874
179 1D2E GDP 1.283e-08 0.58611
180 1DAR GDP 2.095e-08 0.58489
181 1MR3 G3D 3.896e-08 0.58479
182 1KK1 GNP 2.313e-08 0.58307
183 1PUJ GNP 1.848e-08 0.58262
184 1RE0 GDP 2.373e-08 0.581
185 1SKQ GDP 2.364e-08 0.5809
186 2ZEJ GDP 5.271e-08 0.5793
187 1YZG GDP 2.903e-08 0.57816
188 3AQ4 GDP 3.091e-08 0.57731
189 4V0K GDP 2.434e-07 0.57629
190 1A2K GDP 2.947e-08 0.57604
191 3TK1 GDP 1.231e-08 0.57481
192 2HF9 GSP 1.746e-06 0.57229
193 4LC1 GDP 6.767e-08 0.5716
194 1S9D GDP 5.314e-08 0.56977
195 3EC1 GDP 5.375e-08 0.56916
196 3PQC GDP 3.67e-08 0.569
197 1CS4 GSP 1.691e-06 0.56513
198 2HV8 GTP 1.511e-05 0.56406
199 1F6B GDP 3.528e-07 0.56246
200 1BH2 GSP 3.491e-06 0.56112
201 3T12 GDP 1.675e-06 0.55951
202 1AZT GSP 3.049e-06 0.55648
203 1ZCB GDP 2.548e-06 0.5439
204 4KVA GTP 1.436e-06 0.54288
205 1RJ9 GCP 6.498e-05 0.53876
206 3CNL GNP 1.652e-07 0.53667
207 1Y3A GDP 7.68e-06 0.53613
208 2WJG GDP 7.579e-08 0.53485
209 3T1O GDP 1.811e-06 0.53401
210 2XTN GTP 7.952e-06 0.53281
211 1GP2 GDP 8.741e-06 0.53101
212 1GOT GDP 9.749e-06 0.52893
213 4LPS GDP 7.201e-08 0.5267
214 4H1V GNP 2.514e-06 0.52614
215 4HI0 GDP 5.687e-06 0.52076
216 1FQJ GDP 1.37e-05 0.51973
217 3AB3 GDP 6.844e-06 0.51636
218 2OM2 GDP 1.843e-05 0.51411
219 2X2E GDP 4.183e-05 0.51249
220 1FQK GDP 2.43e-05 0.50889
221 1JWY GDP 4.007e-06 0.50849
222 1WDT GTP 6.134e-06 0.50848
223 4JLN 18V 0.0002031 0.5084
224 2Q2Y ADP 0.0006183 0.49835
225 2WJH FLC 3.727e-06 0.49689
226 2ZFI ADP 1.304e-05 0.49414
227 1M7G AV2 0.0008447 0.49083
228 1P72 ADP 0.0001038 0.49065
229 3DC4 ADP 6.088e-07 0.49037
230 4WZA ACP 0.0004841 0.4902
231 2BIF ANP 0.0001279 0.48863
232 1M7G ADP 0.0001907 0.48815
233 1V8K ANP 6.13e-06 0.48621
234 3E70 GDP 0.0001222 0.48534
235 4BFW ZVW 0.0006366 0.48446
236 2WOJ ADP 0.0001637 0.48383
237 2BIF BOG 0.0009039 0.48365
238 2OFW ADX 0.0003263 0.48218
239 4OHY ANP 0.0003304 0.48193
240 3ZFD ANP 1.437e-05 0.48179
241 2ZPA ADP 0.000107 0.48083
242 2IYL GDP 3.415e-05 0.48055
243 1W0J ADP 0.0004752 0.48014
244 4QM7 DC 0.0002492 0.47937
245 3ZIA ADP 1.558e-05 0.47917
246 3T34 GDP 8.32e-05 0.47904
247 3DEF GDP 3.559e-05 0.47857
248 3ZQ6 ADP 0.0002171 0.47634
249 4BQS ADP 0.0002939 0.47612
250 2V7Q ATP 0.0002942 0.4761
251 2QEN ADP 3.54e-05 0.47563
252 4HSE ADP 3.523e-05 0.47559
253 2CK3 ANP 0.0005579 0.47556
254 1X6V ADP 0.001109 0.47478
255 1HTW ADP 5.933e-06 0.47466
256 2PEZ DAT 0.0003809 0.4744
257 3DDC GNP 0.001084 0.47429
258 1W0J ADP 0.0006889 0.47256
259 1IHU ADP 0.001002 0.47185
260 3IIJ ADP 1.165e-05 0.47148
261 1E2K TMC 0.0006186 0.47074
262 1AKY AP5 0.0008543 0.47062
263 4IDN GNP 0.0002627 0.47058
264 1LVK MNT 0.001042 0.46994
265 1ZUI SKM 0.0004496 0.46946
266 3ZIA ATP 3.448e-05 0.46769
267 1NJF ADP 0.0001458 0.46758
268 3E5H GNP 0.001374 0.46734
269 2FNA ADP 0.0002784 0.46732
270 4CVN ADP 8.744e-06 0.46716
271 2KIN ADP 3.698e-07 0.46653
272 2XT3 ADP 1.544e-06 0.46409
273 3H4S ADP 4.545e-07 0.46321
274 3A4M ADP 3.79e-06 0.4631
275 4MKF AP5 0.001103 0.46295
276 2RGX AP5 0.0009859 0.46268
277 2VB6 ADP 0.0003196 0.46246
278 1OXV ANP 1.395e-06 0.46244
279 4P32 ADP 0.0001899 0.46191
280 2VVG ADP 5.97e-07 0.46189
281 1GOJ ADP 5.588e-07 0.46115
282 2GKS ADP 0.0006356 0.46094
283 4MKG AP5 0.001229 0.46074
284 3COB ADP 2.247e-06 0.46063
285 2C04 GCP 0.0001649 0.46053
286 2V26 ADP 0.0002067 0.46043
287 3RLF ANP 0.0004002 0.46037
288 1BG2 ADP 6.53e-07 0.45955
289 2CK3 ADP 0.0004665 0.45952
290 1Y63 ADP 2.462e-05 0.45949
291 2Y65 ADP 6.982e-07 0.4589
292 1R6B ADP 0.001199 0.45871
293 1R0X ATP 0.0002454 0.45853
294 1SVM ATP 0.0004409 0.45851
295 4FRZ ADP 6.706e-07 0.45824
296 1T5C ADP 8.058e-07 0.45785
297 1E4V AP5 0.001531 0.45747
298 2V7Q ADP 9.694e-06 0.45712
299 1KK8 BEF 0.0001572 0.45696
300 1JI0 ATP 6.31e-06 0.45678
301 2JLR ANP 3.423e-05 0.45594
302 3ZS9 ADP 0.0006332 0.45558
303 1DAK ADP 0.00532 0.45555
304 4OI4 ATP 0.0005206 0.45533
305 4KFU ACP 0.0004645 0.45533
306 2BBS ATP 1.105e-06 0.45475
307 3CH5 GDP 0.004732 0.4542
308 1KO8 6PG 0.0002924 0.45413
309 1NJF AGS 0.0003112 0.45401
310 3BOS CDP 1.787e-05 0.45383
311 2ZR9 DTP 2.109e-05 0.45258
312 1FP6 ADP 0.0004763 0.45257
313 2FAH GDP 0.001163 0.45223
314 3FYH ADP 7.732e-05 0.45213
315 3QKT ANP 4.996e-05 0.45206
316 3EWA ANP 4.197e-05 0.45172
317 2B8W ALF 0.0005118 0.45121
318 1LVG ADP 1.059e-05 0.4511
319 2PZE ATP 1.376e-06 0.45042
320 1L2T ATP 0.0008521 0.44983
321 1JWY ADP 9.187e-05 0.44977
322 1OS1 ATP 0.001174 0.44887
323 3QF7 ANP 0.0001782 0.44816
324 1F2U ATP 0.0008417 0.44813
325 3H86 AP5 0.001449 0.44786
326 1XKV ATP 6.098e-05 0.44736
327 1G7C 5GP 3.605e-06 0.44694
328 4E03 ADP 0.0001331 0.44692
329 4QOS ADP 6.702e-05 0.44647
330 1F9V ADP 0.0007692 0.44572
331 4AG5 ADP 1.84e-06 0.44533
332 3LRE ADP 2.352e-06 0.44512
333 3KTA AP5 0.0008034 0.44489
334 3NHB ADP 6.057e-06 0.44441
335 1UKZ ADP 0.00202 0.44415
336 1S3G AP5 0.002228 0.44355
337 1YTM ATP 0.0004083 0.44351
338 2IXE ATP 0.0003359 0.44338
339 2XAU ADP 4.236e-05 0.44325
340 1JJ7 ADP 2.015e-06 0.44197
341 3Q9L ATP 0.000427 0.44148
342 1NHX FTB 0.003387 0.4412
343 4NU0 AP5 0.002913 0.44071
344 1B7T ADP 0.0001052 0.44046
345 3B5J 12D 2.373e-05 0.44042
346 3FB4 AP5 0.002671 0.4399
347 1IWE IMP 0.009069 0.43939
348 2WHX ADP 6.281e-07 0.43917
349 2BEK ATP 0.003163 0.43905
350 4P4T GDP 0.004187 0.43796
351 3VX3 ADP 0.0005477 0.43737
352 1G6H ADP 7.856e-07 0.43731
353 2QZ4 ADP 0.0001276 0.43724
354 2VF7 ADP 0.002705 0.4369
355 1QF9 ADP 0.003319 0.43682
356 3P4X ADP 7.387e-05 0.43665
357 1Z6T ADP 0.0003204 0.43664
358 1VHT BA3 0.0006022 0.43616
359 1Z83 AP5 0.00284 0.43593
360 1FNN ADP 0.0007957 0.43585
361 2QG6 NMN 0.002062 0.43445
362 2WMO GTP 0.004499 0.43425
363 3FWY ADP 0.0006948 0.43312
364 2CBZ ATP 1.403e-06 0.43274
365 1JJV ATP 6.378e-05 0.43251
366 1F5N GNP 0.001546 0.43242
367 1YQT ADP 0.001986 0.43158
368 3IO3 ADP 0.0002512 0.42954
369 2GDJ ANP 0.0002212 0.42952
370 2PL3 ADP 0.0001379 0.42915
371 1W5T ANP 0.001846 0.42903
372 2CHG ANP 0.0005547 0.42881
373 2VF7 ADP 0.004083 0.42868
374 1SQ5 ADP 6.314e-05 0.42828
375 2CDN ADP 0.003635 0.42812
376 3FVQ ATP 0.00055 0.42763
377 2WIC GNP 0.01189 0.42551
378 3EZ2 ADP 0.003164 0.42438
379 1G3Q ADP 0.0005117 0.42389
380 1HE1 AF3 2.778e-06 0.42357
381 2W58 ADP 2.932e-06 0.42299
382 1W4R TTP 0.004538 0.42223
383 1IN4 ADP 0.001716 0.42171
384 1ZIN AP5 0.006666 0.42147
385 2JAQ DCP 0.002575 0.42061
386 1G41 ADP 0.04742 0.42036
387 1H65 GDP 0.01124 0.4196
388 1NY5 ADP 0.0009854 0.41953
389 4AT0 FAD 0.04692 0.41753
390 1OE0 TTP 0.004989 0.41721
391 1W5T ADP 0.003519 0.41673
392 2AWN ADP 1.087e-06 0.41648
393 2B8T THM 0.005736 0.41607
394 1XX6 ADP 9.382e-05 0.41603
395 2D7D ADP 0.0009623 0.41541
396 2OZE AGS 0.01068 0.41432
397 2ZE7 DST 0.004922 0.41406
398 3TMK T5A 0.009453 0.41317
399 3B7G ANP 0.000307 0.41204
400 1ION ADP 0.001042 0.41146
401 4IEE AGS 0.0003018 0.41124
402 1T8U A3P 0.02808 0.41082
403 4TTQ ATP 0.0003256 0.41005
404 1UJ2 C5P 0.03252 0.40694
405 3MD0 GDP 0.01126 0.40569
406 3IUY AMP 0.00126 0.40462
407 4LJ9 ACP 0.0009781 0.40457
408 2V1X ADP 0.0007202 0.40399
409 2YOH WMJ 0.01343 0.40353
410 3FKQ ATP 0.01871 0.40289
411 4IOK ADP 0.0348 0.40105
412 2GK6 ADP 0.0004926 0.39962
413 2FSH ANP 0.001026 0.39914
414 3QVV 3QV 0.02752 0.39906
415 2ZPT A3P 0.03946 0.39758
416 3KJI ADP 0.02509 0.39688
417 4FCW ADP 0.00258 0.39541
418 2YNM ADP 0.03586 0.39538
419 2ZTS ADP 0.03129 0.39442
420 2IL4 COA 0.004691 0.3942
421 3W5J GDP 2.139e-05 0.39391
422 4TMK T5A 0.02333 0.39373
423 1U0J ADP 0.001258 0.39331
424 4MUB OAQ 0.02561 0.39306
425 4HUT ATP 0.0205 0.39099
426 4KVX ACO 0.02071 0.39079
427 1U3U NAD 0.04142 0.39052
428 1OYY AGS 0.002459 0.38985
429 4A4Z ANP 0.002964 0.38811
430 3TBK ANP 0.0007802 0.38714
431 1G3M A3P 0.04113 0.3867
432 2NAD NAD 0.03352 0.3864
433 3RC3 ANP 0.003985 0.38636
434 4GOX A3P 0.01942 0.38405
435 4IV9 FAD 0.04938 0.38393
436 1J99 AND 0.03183 0.38363
437 1G4U AF3 2.974e-05 0.38362
438 2DPY ADP 4.569e-05 0.38314
439 4GBM A3P 0.01987 0.38177
440 2X7B COA 0.03076 0.38151
441 3B4Y F42 0.02998 0.38054
442 2OG2 MLI 1.182e-05 0.38012
443 1BO4 COA 0.003869 0.37953
444 1NST A3P 0.01027 0.37893
445 3B9Q MLI 1.343e-05 0.37893
446 2NGR AF3 0.0001848 0.37852
447 3TO7 COA 0.02874 0.37819
448 1GRN AF3 0.0002181 0.37604
449 3V2U ATP 0.02725 0.37573
450 4IXH IMP 0.04435 0.37564
451 3F8K COA 0.02757 0.37551
452 1BOB ACO 0.03038 0.37542
453 2I4I AMP 0.009195 0.3747
454 2D2F ADP 0.000162 0.37375
455 4KBF AMP 0.004737 0.37355
456 3DZD ADP 0.007561 0.3728
457 4ITM ATP 0.04265 0.37207
458 1AQU A3P 0.01989 0.37172
459 3BD9 A3P 0.01672 0.37151
460 3BFX A3P 0.02932 0.37024
461 3BER AMP 0.007562 0.36939
462 2GWH A3P 0.0249 0.36904
463 4PSW COA 0.01036 0.36855
464 3MGB PAP 0.03364 0.36728
465 2OBM ADP 0.001514 0.36637
466 2WPX ACO 0.02917 0.36637
467 4IX4 ADP 0.04539 0.36589
468 1S7N COA 0.03774 0.36524
469 1Q20 A3P 0.04315 0.36265
470 2X7I CIT 0.006632 0.36201
471 2ZJ5 ADP 0.001017 0.35919
472 1FQK ALF 0.006525 0.35918
473 1FQJ ALF 0.007662 0.35827
474 4NSQ COA 0.04537 0.35772
475 1WQ1 AF3 0.001238 0.35715
476 4QAR ADE 0.04305 0.35449
477 2WPW ACO 0.03662 0.35357
478 1QHH ATP 0.03506 0.35326
479 4NEC SAH 0.04783 0.35014
480 1X9I G6Q 0.04394 0.34831
481 2G77 AF3 0.005412 0.33896
482 1MT6 SAH 0.04791 0.33586
483 1RZX ACE 0.03547 0.33573
484 1CT9 GLN 0.03334 0.33384
485 4CMU IV7 0.0456 0.33379
486 2ORZ LYS 0.02309 0.33278
487 1OW3 MGF 0.007349 0.33041
488 4CU1 H4B 0.02101 0.32599
489 2UYQ SAM 0.03304 0.32439
490 4NZ6 DLY 0.04855 0.32437
491 4CNH 3U9 0.04938 0.32427
492 3FIU POP 0.03355 0.3225
493 4CFT H4B 0.03178 0.32209
494 2VOH CIT 0.00342 0.32116
495 2PIE GLU 0.04179 0.31939
496 2YN4 39J 0.04328 0.31589
497 1Z0N BCD 0.02451 0.31429
498 4QAG F95 0.03968 0.31333
499 2J5V PCA 0.02267 0.30871
500 1K4M CIT 0.03495 0.3054
501 1ZX5 LFR 0.04357 0.30449
502 4G05 JZ3 0.02038 0.30442
503 1I7A PHE 0.02832 0.3027
504 1A8S PPI 0.02991 0.30027
Pocket no: 2; Query (leader) PDB : 1A4R; Ligand: GNH; Similar sites found: 504
This union binding pocket (no: 2) in the query (biounit: 1a4r.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1A4R GNH 1.305e-16 1
2 1A4R GDP 2.442e-15 0.9447
3 1MH1 GNP 1.519e-11 0.79931
4 1Z0K GTP 1.84e-11 0.78812
5 1E96 GTP 1.871e-11 0.78779
6 2WKQ GTP 1.547e-11 0.78747
7 3QBT GNP 2.759e-11 0.77638
8 1RYH GNP 3.093e-13 0.76916
9 4DID GDP 3.537e-13 0.76646
10 3NKV GNP 9.187e-11 0.76425
11 2GCO GNP 1.465e-11 0.76328
12 1TX4 ALF 7.202e-11 0.76182
13 1DS6 GDP 4.923e-13 0.76116
14 1R2Q GNP 1.081e-10 0.76109
15 1NF3 GNP 4.403e-11 0.7591
16 1S8F GDP 1.215e-10 0.7588
17 4ITR GDP 1.882e-12 0.75846
18 2GCN GDP 5.914e-11 0.75774
19 2FJU GSP 6.211e-11 0.75259
20 3TH5 GNP 2.606e-11 0.7523
21 2W2X GSP 2.938e-11 0.75042
22 1GRN GDP 3.804e-12 0.74797
23 3LXR GDP 4.378e-12 0.74764
24 1CLU DBG 6.81e-10 0.74756
25 1HE1 GDP 8.192e-11 0.74735
26 4DSU GDP 3.019e-10 0.74107
27 2BME GNP 1.833e-10 0.74009
28 3REF GDP 1.369e-10 0.73763
29 2NGR GDP 2.402e-12 0.73531
30 1NVU GTP 4.69e-10 0.73249
31 2UZI GTP 4.934e-10 0.7315
32 2J0V GDP 3.773e-12 0.73086
33 4U5X GNP 8.82e-11 0.73085
34 4LHW GNP 4.477e-10 0.73007
35 1Z06 GNP 2.78e-10 0.72826
36 1UAD GNP 4.138e-10 0.72812
37 3TKL GTP 4.68e-10 0.72575
38 1CXZ GSP 1.164e-10 0.72545
39 2EW1 GNP 3.224e-10 0.72544
40 2FFQ GSP 1.011e-09 0.72364
41 2BCG GDP 2.925e-10 0.72326
42 1M7B GTP 1.363e-10 0.72239
43 4HDQ GNP 8.852e-10 0.72012
44 3MJH GTP 6.641e-10 0.719
45 2CL6 CAG 1.313e-09 0.71851
46 1KMQ GNP 4.719e-10 0.71818
47 3RAB GNP 9.675e-10 0.71513
48 4C4P GNP 9.825e-10 0.71484
49 1YZK GNP 8.62e-10 0.71397
50 4K81 GTP 7.484e-10 0.71313
51 4HAT GNP 1.501e-09 0.71291
52 2A5J GDP 1.073e-10 0.71082
53 4KVG GTP 8.651e-10 0.71035
54 1OIX GDP 1.271e-09 0.70984
55 1GWN GTP 3.018e-10 0.70815
56 3TNF GNP 1.416e-09 0.70775
57 1ZC3 GNP 1.982e-09 0.70747
58 4LX0 BEF 1.216e-09 0.70735
59 1NVV GNP 1.751e-09 0.70683
60 3M1I GTP 2.172e-09 0.70567
61 1YZN GNP 1.347e-09 0.70536
62 2C5L GTP 1.426e-09 0.70427
63 1YVD GNP 1.197e-09 0.70413
64 1LFD GNP 1.272e-09 0.70297
65 1XTQ GDP 1.281e-09 0.70283
66 2G77 GDP 1.757e-10 0.70272
67 3BC1 GNP 2.096e-09 0.70015
68 1I4D GDP 1.41e-12 0.69859
69 1Z0A GDP 9.66e-11 0.69787
70 4HDO GNP 2.37e-09 0.69777
71 2D7C GTP 2.002e-09 0.69773
72 1X1R GDP 2.868e-09 0.69408
73 1Z0J GTP 2.835e-09 0.69103
74 1GUA GNP 3.923e-09 0.688
75 3T5G GDP 1.583e-10 0.68737
76 3KUD GDP 2.022e-09 0.68667
77 4TMZ GSP 3.964e-09 0.68456
78 2Y8E GNP 4.108e-09 0.68388
79 2A9K GDP 1.107e-09 0.68373
80 4D0N GDP 1.834e-11 0.68332
81 1VG0 GDP 2.2e-10 0.68263
82 1YZQ GNP 5.376e-09 0.6819
83 2FH5 GTP 3.39e-09 0.68062
84 1KY3 GDP 2.48e-10 0.68047
85 1VG8 GNP 4.926e-09 0.68037
86 1U8Z GDP 4.972e-09 0.6802
87 1WA5 GTP 1.073e-08 0.67984
88 4NON GDP 5.995e-09 0.67978
89 1KSH GDP 3.114e-09 0.6785
90 3SFV GDP 3.823e-09 0.67833
91 1G16 GDP 3.179e-09 0.67811
92 1IBR GNP 7.938e-09 0.67738
93 1TU3 GNP 5.784e-09 0.67728
94 3RWO GDP 9.344e-09 0.6771
95 2F9L GDP 4.933e-09 0.67699
96 1VG9 GDP 8.864e-10 0.67428
97 3WYG GTP 1.017e-08 0.67254
98 1KAO GDP 1.058e-08 0.67178
99 1Z08 GNP 1.099e-08 0.67104
100 2CJW GDP 5.391e-11 0.66704
101 2EFE GNH 3.052e-09 0.66653
102 3BH7 ALF 1.666e-08 0.66577
103 1VG1 GDP 3.181e-10 0.66179
104 1Z0F GDP 2.879e-10 0.66175
105 3CPJ GDP 2.078e-09 0.65942
106 3WYF GTP 2.24e-08 0.65717
107 3GJX GTP 1.995e-08 0.65648
108 4NCN GTP 1.769e-08 0.65252
109 1OW3 GDP 1.499e-10 0.65154
110 1Z2A GDP 2.212e-08 0.64824
111 1EK0 GNP 2.501e-08 0.64588
112 3VMF GTP 2.992e-08 0.6456
113 3DOE GTP 2.036e-08 0.64297
114 3Q85 GNP 3.262e-10 0.64254
115 2C78 GNP 2.255e-08 0.64103
116 1D5C GDP 6.094e-09 0.64036
117 3Q72 GNP 4.39e-10 0.63821
118 1ZD9 GDP 1.454e-08 0.63763
119 4GOJ GNP 2.732e-08 0.6374
120 3GJ0 GDP 3.454e-09 0.63686
121 1G4U GDP 9.431e-10 0.63605
122 4DKX GDP 1.903e-09 0.6311
123 1YRB GDP 6.912e-10 0.63044
124 3GJ7 GDP 2.123e-09 0.63
125 3WY9 GDP 8.09e-10 0.62868
126 1O3Y GTP 6.769e-08 0.6268
127 2GJ8 ALF 1.086e-07 0.62641
128 3GJ5 GDP 2.783e-09 0.62615
129 1J2J GTP 2.74e-08 0.62603
130 3GJ8 GDP 3.067e-09 0.62454
131 3WYA GDP 1.179e-09 0.62358
132 2HCJ GDP 1.181e-09 0.62352
133 3GJ3 GDP 3.549e-09 0.62269
134 3A1S GDP 4.361e-09 0.6226
135 2C77 GNP 6.116e-08 0.62215
136 2W83 GTP 6.192e-08 0.62191
137 2BVN GNP 1.091e-08 0.61941
138 3U6K GDP 4.358e-09 0.61917
139 4M9Q GNP 7.259e-08 0.61891
140 4DCT GDP 2.991e-07 0.61857
141 3GJ4 GDP 4.717e-09 0.61794
142 3WXM GTP 9.731e-08 0.61668
143 4G5G GDP 4.97e-09 0.61639
144 4B47 GDP 2.285e-09 0.61623
145 1D8T GDP 6.347e-09 0.61308
146 3U6B GDP 2.689e-09 0.61244
147 2X77 GDP 3.258e-09 0.60952
148 1UPT GTP 6.841e-08 0.60944
149 4KAX GTP 1.215e-07 0.60915
150 1TQ4 GDP 3.556e-08 0.60899
151 3PCR GTP 1.784e-07 0.60823
152 4P3Y GDP 4.556e-09 0.60511
153 2RCN GDP 3.707e-09 0.60406
154 2A5F GTP 1.603e-07 0.60391
155 1MKY GDP 1.337e-09 0.60348
156 1R4A GNP 1.78e-07 0.60193
157 1WQ1 GDP 9.969e-08 0.60154
158 2QTV GNP 2.969e-07 0.59847
159 1M2O GNP 3.002e-07 0.59826
160 4J0Q GDP 9.195e-09 0.59468
161 1FZQ GDP 9.573e-09 0.59465
162 3N5C GDP 2.529e-08 0.59363
163 1WF3 GNP 3.356e-07 0.5931
164 2QN6 GDP 3.362e-09 0.59254
165 2WJH GDP 1.308e-08 0.59247
166 1G7S GDP 1.091e-08 0.59168
167 2XTZ GSP 4.866e-07 0.589
168 3CX8 GSP 8.471e-07 0.58884
169 2HT6 GDP 4.88e-09 0.58848
170 1SVI GDP 4.356e-09 0.58795
171 1SVK ALF 1.181e-06 0.58692
172 1TAD ALF 1.229e-06 0.58613
173 1D2E GDP 1.387e-08 0.58556
174 2J59 GTP 2.658e-07 0.58526
175 2ODE ALF 1.157e-06 0.58507
176 1DAR GDP 2.402e-08 0.58318
177 1TAD ALF 1.475e-06 0.58252
178 1ZJ6 G3D 2.389e-08 0.58208
179 1SKQ GDP 2.521e-08 0.58031
180 3TK1 GDP 8.649e-09 0.57931
181 1A2K GDP 2.585e-08 0.57824
182 1MR3 G3D 6.125e-08 0.57818
183 1KK1 GNP 3.755e-08 0.57642
184 1PUJ GNP 3.036e-08 0.57609
185 2ZEJ GDP 6.444e-08 0.57595
186 1RE0 GDP 3.522e-08 0.57583
187 4LC1 GDP 5.24e-08 0.57541
188 4BAS GNP 4.748e-07 0.57472
189 1NRJ GTP 7.629e-07 0.57439
190 3AQ4 GDP 4.78e-08 0.57192
191 1YZG GDP 4.987e-08 0.57138
192 3EC1 GDP 4.737e-08 0.57093
193 4V0K GDP 3.65e-07 0.56954
194 3PQC GDP 4.82e-08 0.56507
195 2HF9 GSP 2.694e-06 0.56384
196 1S9D GDP 8.645e-08 0.56373
197 1CS4 GSP 2.061e-06 0.56134
198 1BH2 GSP 3.793e-06 0.55949
199 1AZT GSP 3.134e-06 0.55595
200 1F6B GDP 5.898e-07 0.55367
201 2HV8 GTP 2.724e-05 0.55168
202 3T12 GDP 2.63e-06 0.55096
203 1ZCB GDP 3.059e-06 0.54064
204 4KVA GTP 1.622e-06 0.54005
205 1RJ9 GCP 6.576e-05 0.53851
206 2WJG GDP 7.397e-08 0.53509
207 1Y3A GDP 8.374e-06 0.53447
208 3T1O GDP 2.073e-06 0.53197
209 3CNL GNP 2.832e-07 0.52925
210 2XTN GTP 1.003e-05 0.52838
211 1GOT GDP 1.033e-05 0.52783
212 1GP2 GDP 1.045e-05 0.52761
213 4H1V GNP 3.037e-06 0.52139
214 4LPS GDP 1.304e-07 0.51992
215 1FQJ GDP 1.672e-05 0.51596
216 4HI0 GDP 8.428e-06 0.51411
217 2OM2 GDP 2.144e-05 0.51126
218 3AB3 GDP 1.013e-05 0.51067
219 1FQK GDP 2.335e-05 0.50964
220 4JLN 18V 0.0001989 0.50884
221 2X2E GDP 6.176e-05 0.50486
222 1JWY GDP 5.99e-06 0.50258
223 2WJH FLC 3.598e-06 0.49928
224 2Q2Y ADP 0.0006722 0.49654
225 1WDT GTP 1.911e-05 0.49237
226 2BIF ANP 0.0001114 0.49133
227 3E70 GDP 9.319e-05 0.49056
228 4WZA ACP 0.0004891 0.48998
229 1M7G AV2 0.0009757 0.48771
230 2ZFI ADP 2.004e-05 0.48763
231 3DC4 ADP 7.935e-07 0.48737
232 2BIF BOG 0.0007849 0.48666
233 1M7G ADP 0.0002108 0.48615
234 4BFW ZVW 0.0006031 0.48559
235 2WOJ ADP 0.0001501 0.48552
236 2IYL GDP 2.408e-05 0.48472
237 4OHY ANP 0.0003125 0.48305
238 3ZIA ADP 1.413e-05 0.48042
239 1W0J ADP 0.0004798 0.47994
240 1V8K ANP 9.618e-06 0.47953
241 2OFW ADX 0.0003861 0.47879
242 2ZPA ADP 0.0001194 0.47876
243 2V7Q ATP 0.0002651 0.47815
244 4QM7 DC