Receptor
PDB id Resolution Class Description Source Keywords
1ZTH 1.89 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF A.FULGIDUS RIO1 SERINE PROTEIN KINASE BOUND TO ADP AND MANGANESE ION ARCHAEOGLOBUS FULGIDUS PROTEIN KINASE RIBOSOME BIOGENESIS RRNA ADP MANGANESE TRANSFERASE
Ref.: STRUCTURE AND ACTIVITY OF THE ATYPICAL SERINE KINASE RIO1. FEBS J. V. 272 3698 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:901;
B:903;
C:905;
D:907;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
MN A:902;
B:904;
C:906;
D:908;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
54.938 Mn [Mn+2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZTH 1.89 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF A.FULGIDUS RIO1 SERINE PROTEIN KINASE BOUND TO ADP AND MANGANESE ION ARCHAEOGLOBUS FULGIDUS PROTEIN KINASE RIBOSOME BIOGENESIS RRNA ADP MANGANESE TRANSFERASE
Ref.: STRUCTURE AND ACTIVITY OF THE ATYPICAL SERINE KINASE RIO1. FEBS J. V. 272 3698 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 1ZTH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 1ZTH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 1ZTH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 435
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 ATP 0.9 1
3 A2D 0.895522 0.971831
4 AQP 0.887324 1
5 5FA 0.887324 1
6 AP5 0.884058 0.971831
7 B4P 0.884058 0.971831
8 BA3 0.869565 0.971831
9 AN2 0.84507 0.985915
10 M33 0.833333 0.958333
11 ACQ 0.826667 0.972222
12 A 0.823529 0.971429
13 AMP 0.823529 0.971429
14 ACP 0.821918 0.972222
15 AR6 0.810811 0.971831
16 APR 0.810811 0.971831
17 ANP 0.802632 0.972222
18 AD9 0.8 0.972222
19 AGS 0.8 0.945946
20 SAP 0.8 0.945946
21 ADX 0.783784 0.873418
22 CA0 0.783784 0.945205
23 TAT 0.779221 0.958904
24 AMP MG 0.774648 0.891892
25 50T 0.773333 0.958333
26 ABM 0.763889 0.917808
27 APC 0.763158 0.958904
28 PRX 0.763158 0.893333
29 ATF 0.759494 0.958904
30 A22 0.753086 0.985915
31 A12 0.743243 0.958904
32 AP2 0.743243 0.958904
33 ADP MG 0.736842 0.905405
34 SRA 0.736111 0.918919
35 ADQ 0.73494 0.945205
36 25L 0.732558 0.985915
37 ADP BEF 0.727273 0.881579
38 BEF ADP 0.727273 0.881579
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 ADP PO3 0.708861 0.943662
44 PAP 0.708861 0.985714
45 ATR 0.708861 0.971429
46 SRP 0.707317 0.906667
47 7D3 0.706667 0.905405
48 25A 0.702381 0.971831
49 ATP MG 0.7 0.905405
50 OAD 0.697674 0.945205
51 RBY 0.6875 0.932432
52 ADV 0.6875 0.932432
53 00A 0.686047 0.883117
54 5SV 0.682353 0.848101
55 8QN 0.682353 0.931507
56 OOB 0.682353 0.931507
57 3OD 0.681818 0.945205
58 BIS 0.681818 0.933333
59 ADP ALF 0.674699 0.87013
60 ALF ADP 0.674699 0.87013
61 AMO 0.674419 0.932432
62 4AD 0.674419 0.92
63 PAJ 0.674419 0.884615
64 GAP 0.670732 0.893333
65 MAP 0.670588 0.945946
66 DLL 0.666667 0.931507
67 ANP MG 0.666667 0.894737
68 VO4 ADP 0.666667 0.931507
69 AHX 0.666667 0.896104
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LAD 0.651685 0.860759
75 WAQ 0.651685 0.883117
76 PR8 0.651685 0.85
77 ITT 0.65 0.943662
78 7D4 0.65 0.905405
79 G5P 0.648936 0.921053
80 RAB 0.647059 0.84507
81 ADN 0.647059 0.84507
82 XYA 0.647059 0.84507
83 TXA 0.644444 0.932432
84 1ZZ 0.644444 0.839506
85 ME8 0.644444 0.839506
86 NB8 0.644444 0.896104
87 FYA 0.644444 0.905405
88 6AD 0.642857 0.909091
89 ADP BMA 0.640449 0.918919
90 G3A 0.638298 0.921053
91 DAL AMP 0.632184 0.905405
92 AFH 0.631579 0.884615
93 9SN 0.630435 0.871795
94 GTA 0.625 0.886076
95 YAP 0.623656 0.894737
96 FA5 0.623656 0.906667
97 UP5 0.622449 0.92
98 XAH 0.617021 0.839506
99 AV2 0.616279 0.917808
100 AOC 0.615385 0.821918
101 48N 0.612245 0.896104
102 4UV 0.610526 0.894737
103 TXD 0.606061 0.907895
104 DND 0.606061 0.932432
105 NAX 0.606061 0.873418
106 NXX 0.606061 0.932432
107 NAI 0.606061 0.907895
108 6V0 0.606061 0.896104
109 5N5 0.605634 0.819444
110 5AS 0.604938 0.77907
111 A4P 0.60396 0.843373
112 DAT 0.60241 0.905405
113 A2R 0.602273 0.985915
114 TXE 0.6 0.907895
115 OMR 0.6 0.851852
116 4UU 0.597938 0.894737
117 A A 0.597826 0.944444
118 A4D 0.597222 0.819444
119 5CD 0.597222 0.805556
120 AP0 0.594059 0.896104
121 4TC 0.594059 0.896104
122 A3P 0.592593 0.971429
123 139 0.592233 0.873418
124 T5A 0.592233 0.841463
125 7D5 0.592105 0.878378
126 ATP A A A 0.589474 0.930556
127 LAQ 0.585859 0.839506
128 MYR AMP 0.585106 0.817073
129 YLP 0.58 0.819277
130 UPA 0.578431 0.907895
131 7DD 0.578313 0.985714
132 ADJ 0.576923 0.851852
133 3AM 0.576923 0.929577
134 COD 0.575472 0.811765
135 NAD 0.575472 0.931507
136 3AT 0.574713 0.971831
137 JB6 0.574468 0.883117
138 4UW 0.574257 0.860759
139 EP4 0.573333 0.753247
140 A2P 0.573171 0.957143
141 CNA 0.571429 0.932432
142 TYM 0.568627 0.906667
143 PPS 0.568182 0.873418
144 TYR AMP 0.56701 0.881579
145 DTA 0.565789 0.786667
146 M2T 0.565789 0.734177
147 AR6 AR6 0.565657 0.917808
148 A3D 0.564815 0.918919
149 3DH 0.564103 0.773333
150 G5A 0.563218 0.77907
151 YLB 0.563107 0.819277
152 YLC 0.563107 0.839506
153 AMP DBH 0.561224 0.893333
154 MTA 0.558442 0.773333
155 DTP 0.556818 0.905405
156 AHZ 0.554455 0.817073
157 NA7 0.553191 0.958904
158 IOT 0.552381 0.831325
159 7MD 0.55 0.8625
160 ZAS 0.55 0.766234
161 IMO 0.548781 0.929577
162 YLA 0.54717 0.819277
163 NAE 0.544643 0.894737
164 TAD 0.544554 0.884615
165 A5A 0.544444 0.807229
166 2AM 0.544304 0.943662
167 TSB 0.543478 0.819277
168 6RE 0.54321 0.759494
169 AYB 0.542056 0.809524
170 NAQ 0.539823 0.871795
171 V3L 0.539326 0.971831
172 ARG AMP 0.539216 0.829268
173 AF3 ADP 3PG 0.538462 0.8375
174 SSA 0.538462 0.8
175 LA8 ALF 3PG 0.538462 0.8375
176 ALF ADP 3PG 0.538462 0.8375
177 ZID 0.535088 0.918919
178 LPA AMP 0.533981 0.817073
179 54H 0.532609 0.788235
180 52H 0.532609 0.77907
181 VMS 0.532609 0.788235
182 BTX 0.53211 0.841463
183 J7C 0.53012 0.769231
184 A3N 0.53012 0.786667
185 5X8 0.528736 0.763158
186 BT5 0.527273 0.831325
187 5CA 0.526882 0.8
188 53H 0.526882 0.77907
189 ARU 0.526316 0.860759
190 EAD 0.525862 0.873418
191 RGT 0.525253 0.958904
192 OVE 0.52439 0.905405
193 S4M 0.52381 0.666667
194 7DT 0.522727 0.985714
195 GDP 0.522222 0.92
196 DDS 0.522222 0.878378
197 AVV 0.521277 0.896104
198 NDE 0.521008 0.932432
199 7MC 0.518868 0.841463
200 DSH 0.518072 0.725
201 MAO 0.517647 0.759036
202 LSS 0.515789 0.761364
203 DSZ 0.515789 0.8
204 NSS 0.515789 0.8
205 P5A 0.515464 0.744444
206 DZD 0.513514 0.884615
207 NVA LMS 0.510417 0.761364
208 12D 0.509615 0.785714
209 NAD IBO 0.509091 0.87013
210 M24 0.508772 0.85
211 YLY 0.508772 0.809524
212 P1H 0.508333 0.851852
213 5AD 0.506849 0.746479
214 GJV 0.505882 0.75
215 LEU LMS 0.505155 0.761364
216 G A A A 0.504505 0.871795
217 4TA 0.504505 0.807229
218 NAJ PZO 0.504425 0.848101
219 KAA 0.5 0.752809
220 NDC 0.5 0.871795
221 7D7 0.5 0.743243
222 71V 0.5 0.907895
223 A3G 0.5 0.8
224 128 0.5 0.776471
225 GSU 0.5 0.77907
226 N0B 0.495726 0.819277
227 NJP 0.495495 0.945946
228 ODP 0.495495 0.909091
229 2SA 0.494624 0.932432
230 6C6 0.494505 0.881579
231 SFG 0.494382 0.75
232 0WD 0.491071 0.921053
233 YSA 0.490196 0.77907
234 PO4 PO4 A A A A PO4 0.489796 0.902778
235 6IA 0.48913 0.8375
236 SAM 0.48913 0.690476
237 A7D 0.488636 0.776316
238 6FA 0.488 0.841463
239 FB0 0.487805 0.804598
240 NAJ PYZ 0.487179 0.85
241 IDP 0.483516 0.918919
242 A5D 0.483516 0.786667
243 SA8 0.483516 0.707317
244 MHZ 0.483146 0.697674
245 PGS 0.483146 0.883117
246 D5M 0.482353 0.878378
247 DA 0.482353 0.878378
248 NEC 0.482353 0.746667
249 NIA 0.481928 0.822785
250 Y3J 0.480519 0.726027
251 FAD 0.480315 0.851852
252 FAS 0.480315 0.851852
253 FDA 0.48 0.833333
254 N6P 0.479592 0.915493
255 GGZ 0.479167 0.825
256 SAH 0.478261 0.74359
257 SAI 0.478261 0.734177
258 NPW 0.477477 0.886076
259 NDP 0.477477 0.921053
260 AAM 0.476744 0.971429
261 AMZ 0.47561 0.916667
262 C2R 0.47561 0.90411
263 A A A 0.474747 0.905405
264 GTP 0.473684 0.92
265 U A G G 0.473684 0.883117
266 SMM 0.473684 0.686047
267 TXP 0.473214 0.921053
268 NZQ 0.473214 0.909091
269 A3S 0.47191 0.810811
270 AMP NAD 0.470588 0.881579
271 SFD 0.46875 0.734043
272 AIR 0.468354 0.901408
273 AAT 0.468085 0.707317
274 EEM 0.468085 0.690476
275 Z5A 0.466667 0.77907
276 7C5 0.466667 0.818182
277 J7V 0.466667 0.833333
278 62F 0.465649 0.8625
279 FAY 0.462121 0.8625
280 ETB 0.461538 0.833333
281 DCA 0.461538 0.823529
282 A3T 0.461538 0.821918
283 A6D 0.46 0.722892
284 A U 0.459459 0.87013
285 6K6 0.459184 0.930556
286 GEK 0.459184 0.7375
287 RFL 0.458647 0.821429
288 S7M 0.458333 0.690476
289 NAP 0.458333 0.945205
290 4YB 0.457944 0.761364
291 WSA 0.454545 0.788235
292 TAP 0.454545 0.907895
293 FNK 0.454545 0.804598
294 COA 0.453782 0.823529
295 0T1 0.453782 0.823529
296 101 0.453488 0.878378
297 XNP 0.452174 0.873418
298 NA0 0.45082 0.932432
299 7RP 0.448276 0.928571
300 GP3 0.446809 0.921053
301 TM1 0.446602 0.77381
302 APU 0.446429 0.894737
303 PUA 0.445378 0.884615
304 V1N 0.443396 0.917808
305 7RA 0.443182 0.957747
306 30N 0.442623 0.752688
307 CAO 0.442623 0.795455
308 AMX 0.442623 0.833333
309 COS 0.442623 0.804598
310 ACK 0.44186 0.861111
311 QQY 0.44186 0.815789
312 649 0.441441 0.744444
313 0UM 0.44 0.698795
314 NHD 0.439655 0.905405
315 CMX 0.439024 0.823529
316 SCO 0.439024 0.823529
317 GCP 0.438776 0.896104
318 8BR 0.438202 0.906667
319 GNH 0.4375 0.907895
320 3AD 0.4375 0.805556
321 62X 0.435644 0.666667
322 ACO 0.435484 0.795455
323 FCX 0.435484 0.795455
324 FAM 0.435484 0.804598
325 GNP 0.434343 0.896104
326 NMX 0.433071 0.76087
327 MGP 0.43299 0.884615
328 PLP AAD 0.432203 0.741573
329 26A 0.432099 0.763158
330 HAX 0.432 0.804598
331 K15 0.431373 0.682353
332 DG1 0.430894 0.921053
333 1DG 0.430894 0.921053
334 QQX 0.430233 0.805195
335 2VA 0.430108 0.8
336 S8M 0.43 0.759494
337 2MC 0.429688 0.769231
338 3KK 0.428571 0.804598
339 6G0 0.428571 0.884615
340 FYN 0.428571 0.823529
341 P5F 0.428571 0.823529
342 NAD BBN 0.428571 0.841463
343 U G A 0.427481 0.839506
344 AS 0.426966 0.833333
345 FAI 0.426966 0.916667
346 RMB 0.426966 0.873239
347 1RB 0.425287 0.885714
348 MCD 0.425197 0.804598
349 OXK 0.425197 0.804598
350 COK 0.425197 0.804598
351 CA6 0.425197 0.729167
352 SOP 0.425197 0.804598
353 G1R 0.424242 0.907895
354 CC5 0.423077 0.816901
355 SXZ 0.423077 0.710843
356 F2N 0.422535 0.813953
357 NAD CJ3 0.422222 0.811765
358 ANZ 0.422018 0.8
359 CMC 0.421875 0.804598
360 CO6 0.421875 0.804598
361 1VU 0.421875 0.795455
362 ZDA 0.421053 0.864865
363 GDD 0.420561 0.884615
364 GKE 0.420561 0.884615
365 GDC 0.420561 0.884615
366 NFD 0.420168 0.883117
367 GSP 0.42 0.873418
368 D3Y 0.42 0.789474
369 MC4 0.419847 0.76087
370 3L1 0.419753 0.773333
371 3D1 0.419753 0.773333
372 FA9 0.41958 0.864198
373 5GP 0.419355 0.906667
374 G 0.419355 0.906667
375 KB1 0.419048 0.698795
376 SCD 0.418605 0.823529
377 CAJ 0.418605 0.804598
378 2BA 0.417582 0.915493
379 CMP 0.417582 0.901408
380 SO8 0.416667 0.789474
381 N01 0.416667 0.905405
382 VRT 0.416667 0.769231
383 3HC 0.415385 0.813953
384 A1S 0.415385 0.804598
385 BCO 0.415385 0.804598
386 IVC 0.415385 0.813953
387 MLC 0.415385 0.804598
388 1HE 0.415385 0.786517
389 NMN AMP PO4 0.415254 0.87013
390 2FA 0.414634 0.813333
391 MGO 0.414141 0.860759
392 3NZ 0.413462 0.782051
393 MCA 0.412214 0.795455
394 CAA 0.412214 0.813953
395 YE1 0.412214 0.813953
396 COO 0.412214 0.804598
397 GAV 0.411765 0.884615
398 P2P 0.411111 0.902778
399 JLN 0.411111 0.890411
400 ZZB 0.410256 0.77381
401 CNV FAD 0.410072 0.793103
402 SCA 0.409091 0.804598
403 RP1 0.409091 0.842105
404 103 0.409091 0.837838
405 2CP 0.409091 0.795455
406 SP1 0.409091 0.842105
407 PAX 0.408 0.829268
408 FAD NBT 0.407143 0.75
409 NVA 2AD 0.40625 0.74359
410 COW 0.406015 0.795455
411 BYC 0.406015 0.804598
412 2KQ 0.406015 0.786517
413 COF 0.406015 0.786517
414 3CP 0.406015 0.804598
415 IRC 0.406015 0.813953
416 1GZ 0.406015 0.795455
417 HGG 0.406015 0.804598
418 CA8 0.406015 0.729167
419 G2P 0.405941 0.884615
420 SLU 0.404959 0.770115
421 U A C C 0.404959 0.858974
422 RBZ 0.404494 0.849315
423 1CZ 0.404412 0.795455
424 BCA 0.402985 0.795455
425 FAQ 0.402985 0.804598
426 4CA 0.402985 0.795455
427 MTP 0.402439 0.730769
428 8OD 0.402062 0.945205
429 CO7 0.401515 0.804598
430 DAL FAD PER 0.401408 0.809524
431 G2R 0.4 0.884615
432 HXC 0.4 0.786517
433 ENQ 0.4 0.916667
434 GMV 0.4 0.896104
435 GRA 0.4 0.804598
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZTH; Ligand: ADP; Similar sites found: 309
This union binding pocket(no: 1) in the query (biounit: 1zth.bio4) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4U98 ACP 0.00003567 0.4809 1.16279
2 2PUL ACP 0.0000006031 0.55083 1.93798
3 5LI1 ANP 0.0000001025 0.53391 1.93798
4 3SLS ANP 0.000003369 0.48212 1.93798
5 3MVH WFE 0.0000005921 0.45009 1.93798
6 3VPC ADP 0.00009976 0.43183 1.93798
7 3CH6 311 0.04228 0.4136 1.93798
8 3CH6 NAP 0.04228 0.4136 1.93798
9 2FXD DR7 0.01064 0.42449 2.0202
10 3TXO 07U 0.0000001635 0.63227 2.32558
11 5UIU 8CG 0.000001141 0.62399 2.32558
12 4YMJ 4EJ 0.000002427 0.59535 2.32558
13 4G17 0VN 0.000004406 0.56462 2.32558
14 1K3A ACP 0.00001186 0.54108 2.32558
15 4Y0X ADP 0.000004172 0.53657 2.32558
16 3NW7 LGV 0.0005323 0.50776 2.32558
17 5LXM ADP 0.00003153 0.48742 2.32558
18 5T8O 76Z 0.000005588 0.48568 2.32558
19 2PZI AXX 0.0002199 0.46903 2.32558
20 3E5A VX6 0.00007844 0.42768 2.32558
21 5IH9 6BF 0.000003455 0.41242 2.32558
22 5JGA 6KC 0.00001213 0.40916 2.32558
23 4AT3 LTI 0.00004409 0.40857 2.32558
24 5W2I ADP 0.00001254 0.44087 2.33463
25 5W2I I3P 0.00001254 0.44087 2.33463
26 1RE8 BD2 0.000003545 0.62189 2.71318
27 1O9U ADZ 0.000002874 0.6115 2.71318
28 5JFS 6K0 0.00000552 0.60481 2.71318
29 5X8I SQZ 0.0000002456 0.55439 2.71318
30 4CYI ATP 0.00001466 0.55108 2.71318
31 4OTH DRN 0.0000005409 0.51328 2.71318
32 2F57 23D 0.00004104 0.48972 2.71318
33 4WB6 ATP 0.0000002752 0.48085 2.71318
34 3X01 AMP 0.001706 0.44987 2.71318
35 3LXK MI1 0.00000965 0.4376 2.71318
36 4WB7 ATP 0.000001049 0.41492 2.71318
37 5C1P ADP 0.00596 0.4062 2.71318
38 5EXK 5AD 0.01398 0.40305 2.71318
39 3V8S 0HD 0.000000751 0.60436 3.10078
40 3PLS ANP 0.0000007945 0.6032 3.10078
41 2F2U M77 0.000003665 0.56146 3.10078
42 2IF8 ADP 0.00001012 0.55768 3.10078
43 5FBN 5WF 0.00004121 0.55238 3.10078
44 3WVR AMP 0.0002173 0.48456 3.10078
45 3H9R TAK 0.00012 0.48206 3.10078
46 5UOX 8GY 0.000009444 0.47099 3.10078
47 2R5T ANP 0.000009077 0.46848 3.10078
48 3FHR P4O 0.00003481 0.46573 3.10078
49 1IA9 ANP 0.0001213 0.44712 3.10078
50 3TII ANP 0.001046 0.44699 3.10078
51 4NW6 2NS 0.000001287 0.43447 3.10078
52 5HX8 66P 0.00002735 0.43335 3.10078
53 4Y93 746 0.00003125 0.4321 3.10078
54 4L3L 5FI 0.000001189 0.62309 3.48837
55 2V7O DRN 0.00000014 0.61455 3.48837
56 3TKI S25 0.0000173 0.59283 3.48837
57 5MW8 ATP 0.000004426 0.58136 3.48837
58 5HES 032 0.000003958 0.58123 3.48837
59 2XK9 XK9 0.00002092 0.56896 3.48837
60 2VN9 GVD 0.000001564 0.56712 3.48837
61 5I35 ANP 0.0000003896 0.56337 3.48837
62 5LPZ ADP 0.0000001562 0.56104 3.48837
63 5LPB ADP 0.000004408 0.55772 3.48837
64 3F7Z 34O 0.0000003356 0.55076 3.48837
65 5LVP ATP 0.000007565 0.55025 3.48837
66 4OH4 ANP 0.0000005763 0.5386 3.48837
67 3ZRM ZRM 0.000000891 0.53109 3.48837
68 2HY0 306 0.00001609 0.5178 3.48837
69 2VZ6 FEF 0.0000257 0.51091 3.48837
70 5DBX ANP 0.00006812 0.50543 3.48837
71 3CY2 MB9 0.0000009403 0.49205 3.48837
72 4NM5 ADP 0.000002097 0.479 3.48837
73 4E1Z 0MX 0.00002181 0.45427 3.48837
74 2JLD AG1 0.0000007412 0.43323 3.48837
75 4QTB 38Z 0.0000131 0.42675 3.48837
76 2YAK OSV 0.0000004401 0.64477 3.87597
77 2B9H ADP 0.0000004613 0.62086 3.87597
78 5LXC 7AA 0.0000003304 0.61782 3.87597
79 2H8H H8H 0.000002184 0.58539 3.87597
80 1PHK ATP 0.000002534 0.58522 3.87597
81 4CLI 5P8 0.00002074 0.57912 3.87597
82 4H3P ANP 0.000003681 0.57453 3.87597
83 2B9J ADP 0.0000003645 0.56299 3.87597
84 2B9F ADP 0.0000003974 0.54775 3.87597
85 2B9I ADP 0.0000006281 0.54014 3.87597
86 3DAK ANP 0.00000284 0.53867 3.87597
87 4IX4 ADP 0.00002855 0.53705 3.87597
88 3HZT J60 0.00002963 0.51915 3.87597
89 4H3Q ANP 0.000001444 0.48656 3.87597
90 3PDT ADP 0.00006022 0.48489 3.87597
91 2X2M X2M 0.000003356 0.47879 3.87597
92 1Y57 MPZ 0.000003191 0.47555 3.87597
93 3ALN ANP 0.000009781 0.47264 3.87597
94 4ZS4 ATP 0.00009231 0.45176 3.87597
95 4UWH JXM 0.0007652 0.43662 3.87597
96 4WNK 453 0.00002614 0.41594 3.87597
97 4DFU QUE 0.007968 0.41512 3.87597
98 2IO8 ADP 0.0003643 0.40462 3.87597
99 1GPM AMP 0.02979 0.40386 3.87597
100 2QK4 ATP 0.006859 0.40386 3.87597
101 4IJP 1EH 0.000000877 0.61033 4.26357
102 1Q8Y ADP 0.000001589 0.59782 4.26357
103 1Q8Y ADE 0.000007229 0.53763 4.26357
104 1W2D ADP 0.00002983 0.51901 4.26357
105 1ZY5 ANP 0.000006634 0.50918 4.26357
106 4OUC 5ID 0.00006726 0.50865 4.26357
107 1TZD ADP 0.000003057 0.48886 4.26357
108 5HVJ ANP 0.0003115 0.48663 4.26357
109 2VPQ ANP 0.0004235 0.48441 4.26357
110 4WOV 3SM 0.0002027 0.46999 4.26357
111 5C03 AGS 0.00004091 0.46899 4.26357
112 3ETH ATP 0.00094 0.46554 4.26357
113 4KS7 X4Z 0.00001435 0.45406 4.26357
114 2QLU ADE 0.002429 0.44155 4.26357
115 4E93 GUI 0.00000187 0.42688 4.26357
116 1W2D 4IP 0.0001177 0.40172 4.26357
117 5L8L ADP 0.00005731 0.5058 4.2735
118 4YLL 4E3 0.000001479 0.60466 4.65116
119 4ASE AV9 0.000005924 0.58408 4.65116
120 3M2W L8I 0.000001892 0.55923 4.65116
121 5CEO 50D 0.00004064 0.52458 4.65116
122 2RIO ADP 0.00001418 0.50051 4.65116
123 3DNT ATP 0.0004642 0.48438 4.65116
124 4BHN BH9 0.000006181 0.48376 4.65116
125 5DH3 5BS 0.0000438 0.45645 4.65116
126 4KBA 1QM 0.00001508 0.42451 4.65116
127 3KCC CMP 0.007853 0.41695 4.65116
128 5W4W 9WG 0.00006033 0.40044 4.65116
129 3HEE R5P 0.0109 0.40377 4.69799
130 4EKQ NPO 0.01037 0.40048 4.81283
131 3IDB ANP 0.0000007796 0.49473 4.96894
132 4K33 ACP 0.000002204 0.58814 5.03876
133 4I94 ANP 0.000004186 0.56884 5.03876
134 5EOB 5QQ 0.00006294 0.56405 5.03876
135 2WQN ADP 0.000019 0.51449 5.03876
136 3VOT ADP 0.0005641 0.4595 5.03876
137 4AUA 4AU 0.0004231 0.44445 5.03876
138 1VJY 460 0.000002524 0.42266 5.03876
139 2A19 ANP 0.0000007122 0.59462 5.14286
140 4XV1 904 0.0000006099 0.64371 5.42636
141 2HK5 1BM 0.00000239 0.58924 5.42636
142 3DLS ADP 0.000002243 0.57848 5.42636
143 1BYG STU 0.00000549 0.56011 5.42636
144 2PVF ACP 0.000001131 0.54398 5.42636
145 4DC2 ADE 0.000002038 0.51543 5.42636
146 5LI9 ACP 0.000001909 0.51113 5.42636
147 4YZN 4K5 0.0000009389 0.49448 5.42636
148 5MJA 7O3 0.00003457 0.49227 5.42636
149 4CQE CQE 0.000001705 0.48777 5.42636
150 2R7K AMZ 0.001147 0.47166 5.42636
151 3GC8 B45 0.00001704 0.4546 5.42636
152 3RI1 3RH 0.000005719 0.45389 5.42636
153 2Y6O 1N1 0.00002168 0.44991 5.42636
154 4LOO SB4 0.0001418 0.44866 5.42636
155 3VRY B43 0.00000837 0.44329 5.42636
156 2R85 AMP 0.006877 0.43537 5.42636
157 3VHE 42Q 0.00001225 0.41055 5.42636
158 5UR1 YY9 0.00006204 0.40093 5.42636
159 4N9I PCG 0.04809 0.40772 5.71429
160 2QCS ANP 0.0000002574 0.64955 5.81395
161 5GZ9 ANP 0.000006581 0.57293 5.81395
162 2XVD AS6 0.000027 0.55315 5.81395
163 3GGF GVD 0.000007068 0.52451 5.81395
164 5EFQ ADP 0.000002851 0.51546 5.81395
165 3UIM ANP 0.000005661 0.50328 5.81395
166 4FG8 ATP 0.000002733 0.5009 5.81395
167 5U6C 7YS 0.000002133 0.49183 5.81395
168 2AQX ATP 0.0001925 0.41991 5.81395
169 4UAL 3FV 0.0000003941 0.621 6.20155
170 4BTK DTQ 0.000003081 0.57823 6.20155
171 1GSA ADP 0.00008892 0.51759 6.20155
172 3IGO ANP 0.0000004198 0.51267 6.20155
173 4NFN 2KC 0.000008403 0.50731 6.20155
174 5EKO N17 0.0001886 0.50161 6.20155
175 4OCV ANP 0.00001006 0.4843 6.20155
176 3AQV TAK 0.0002974 0.48317 6.20155
177 4EWH T77 0.000009452 0.4371 6.20155
178 4A4X JUP 0.00002095 0.42582 6.20155
179 3C1X CKK 0.000258 0.41353 6.20155
180 4NST ADP 0.000002292 0.58438 6.58915
181 2PYW ADP 0.00000003365 0.55741 6.58915
182 1XJD STU 0.0000003441 0.53884 6.58915
183 3AKK ADP 0.0002352 0.49043 6.58915
184 4I6H 1C8 0.0001404 0.44896 6.58915
185 5TA6 79D 0.000005959 0.43441 6.58915
186 3KRL KRL 0.0002065 0.42336 6.58915
187 5USZ SKE 0.00003963 0.41814 6.58915
188 4CSV STI 0.0002027 0.40966 6.58915
189 4GJ3 0XP 0.000003262 0.60302 6.97674
190 4EUU BX7 0.000007799 0.57605 6.97674
191 5DA3 58V 0.0000196 0.52751 6.97674
192 3LXN MI1 0.000002082 0.50368 6.97674
193 3VPD ANP 0.0003116 0.48889 6.97674
194 5H2U 1N1 0.00002781 0.47335 6.97674
195 5DZT AMP 0.008025 0.41604 6.97674
196 2VQD AP2 0.001013 0.4082 6.97674
197 2WEL K88 0.00002418 0.48985 7.33333
198 5M06 ADP 0.000004259 0.52678 7.36434
199 3SXS PP2 0.00001541 0.46342 7.36434
200 1IOW PHY 0.006132 0.44162 7.36434
201 1AUX AGS 0.001067 0.41774 7.36434
202 5K2M ADP 0.0001116 0.51483 7.54717
203 4XH0 ADP 0.000008934 0.56568 7.75194
204 2X4Z X4Z 0.00002461 0.56378 7.75194
205 4JDI ANP 0.000003361 0.49094 7.75194
206 4O4F ATP 0.0002024 0.40443 8.06452
207 3PVW QRX 0.00001067 0.43683 8.10811
208 4O1P ANP 0.000002908 0.57943 8.13953
209 3UDZ ADP 0.000004423 0.57356 8.13953
210 4WNP 3RJ 0.000000999 0.57208 8.13953
211 2OFV 242 0.00006174 0.54494 8.13953
212 1U59 STU 0.000006141 0.50666 8.13953
213 5C4L SIS 0.0002888 0.50485 8.13953
214 5C4L 4XR 0.0003969 0.49789 8.13953
215 5FI4 5XV 0.008683 0.42174 8.13953
216 4ZGP ADP 0.001714 0.41586 8.13953
217 2GQR ADP 0.01023 0.40748 8.43882
218 2GQS ADP 0.01394 0.40103 8.43882
219 5EYK 5U5 0.0001091 0.40968 8.47458
220 5TDF ADP 0.001992 0.44773 8.52713
221 3W0O HY0 0.00001615 0.42042 8.52713
222 3W0O ADP 0.00001615 0.42042 8.52713
223 4YZC STU 0.000007059 0.5947 8.91473
224 4M69 ANP 0.000005019 0.57363 8.91473
225 4XLI 1N1 0.00002308 0.48913 8.91473
226 5VZ0 ADP 0.0001314 0.46058 8.91473
227 3Q60 ATP 0.0008406 0.45923 8.91473
228 4Y85 499 0.0004654 0.44038 8.91473
229 5A6N U7E 0.0000001588 0.64317 9.30233
230 4X7Q 3YR 0.0000008713 0.53494 9.30233
231 2Z7R STU 0.0000003131 0.5198 9.30233
232 4L9I 8PR 0.0009805 0.42681 9.30233
233 5UKL SIX 0.000009005 0.57501 9.67742
234 2YAB AMP 0.0000005657 0.61659 9.68992
235 3BU5 ATP 0.00000274 0.58067 9.68992
236 5DMZ ADP 0.0000008351 0.53781 9.68992
237 3C0G 3AM 0.000008514 0.53048 9.68992
238 4AU8 Z3R 0.00004965 0.5087 9.68992
239 4R78 AMP 0.00008701 0.50428 9.68992
240 2OO8 RAJ 0.009488 0.41655 9.68992
241 2YRX AMP 0.001745 0.41378 9.68992
242 3FHI ANP 0.0000003988 0.64012 9.74026
243 5CKW ANP 0.0000008641 0.5907 10.0775
244 4JR7 GNP 0.0000002989 0.55443 10.0775
245 2WU6 DKI 0.000000416 0.50205 10.0775
246 3PP0 03Q 0.000006205 0.44082 10.0775
247 1M0W ANP 0.00497 0.42024 10.0775
248 2XMY CDK 0.00004378 0.58102 10.4651
249 4CFU 2WC 0.00000214 0.54193 10.4651
250 4U0I 0LI 0.00005919 0.53956 10.4651
251 4BCN T9N 0.000008385 0.53132 10.4651
252 2WEI VGG 0.00005686 0.5121 10.4651
253 4BCQ TJF 0.00004437 0.51098 10.4651
254 4IDT T28 0.000009516 0.50788 10.4651
255 4BCM T7Z 0.00007113 0.48211 10.4651
256 5LMK 6ZK 0.0004452 0.44434 10.4651
257 5VC5 96M 0.00001451 0.43222 10.4651
258 2ZV2 609 0.000001516 0.57932 10.8527
259 4OAV ACP 0.000002481 0.52805 10.8527
260 1V0O INR 0.00000602 0.49282 10.8527
261 5MY8 RXZ 0.000002815 0.45638 10.8527
262 2PVN P63 0.000001357 0.4528 10.8527
263 3GQI ACP 0.000007967 0.49952 11.0619
264 5G1X ADP 0.00005441 0.47897 11.1111
265 3PE2 E1B 0.00001111 0.59587 11.2403
266 3OFM 4B0 0.000002324 0.57432 11.2403
267 3TDV GDP 0.0000232 0.48006 11.2403
268 3ORK AGS 0.00000651 0.45714 11.2403
269 4C2V YJA 0.001118 0.47374 11.3636
270 4C2W ANP 0.00006416 0.50351 11.5385
271 4USF 6UI 0.00008693 0.52016 11.6279
272 3E7O 35F 0.0001735 0.51602 11.6279
273 4UX9 ANP 0.000001228 0.50845 11.6279
274 5JKG 6LF 0.0007291 0.49267 11.6279
275 4IZY 1J2 0.000005642 0.47841 11.6279
276 3PTG 932 0.0008458 0.44631 11.6279
277 3TTI KBI 0.000009361 0.43231 11.6279
278 4CRL C1I 0.000002189 0.41789 11.6279
279 3ZZS TRP 0.01027 0.40527 12.3077
280 4U44 3D9 0.000002801 0.58021 12.4031
281 5IQD RIO 0.00001859 0.57463 12.4031
282 5IQD GNP 0.00001738 0.57463 12.4031
283 4F9C 0SX 0.0000002689 0.56585 12.4031
284 3SRV S19 0.0000001584 0.63653 12.7907
285 4F4P 0SB 0.00003518 0.58153 12.7907
286 2BKK ADP 0.00002316 0.52743 12.7907
287 4FL3 ANP 0.00000166 0.49139 12.7907
288 4D2S DYK 0.0000879 0.48468 12.7907
289 3HMO STU 0.00003298 0.48195 12.7907
290 4LRJ ANP 0.0001827 0.45529 13.0178
291 4WW7 AMP 0.0000003136 0.63486 13.1783
292 2J7T 274 0.0001569 0.51658 13.1783
293 5AX9 4KT 0.000007746 0.496 13.1783
294 1UNH IXM 0.000009591 0.54541 13.5659
295 5AWM ANP 0.000008744 0.54385 13.9535
296 4Y8D 49J 0.0000003778 0.54393 14.7287
297 5JZJ AN2 0.0000005155 0.55553 15.1163
298 3KN5 ANP 0.00008738 0.50036 15.1163
299 4AZW ATP 0.00003662 0.53181 15.5039
300 3SXF BK5 0.000003836 0.60491 18.2171
301 3O0G 3O0 0.00001124 0.54843 18.7919
302 4BFM ANP 0.0000001867 0.54132 18.9922
303 2CSN CKI 0.0000003315 0.48411 20.5426
304 4Q5H ANP 0.000002145 0.51947 21.2644
305 2UYN 2KT 0.01057 0.40377 21.7054
306 5VCV 1N1 0.000001056 0.48266 22.8682
307 3VPB ADP 0.0001143 0.41662 23.2143
308 5C8W PCG 0.006211 0.40544 28.6713
309 5HQ0 LZ9 0.0000005305 0.51649 34.5238
Pocket No.: 2; Query (leader) PDB : 1ZTH; Ligand: ADP; Similar sites found: 11
This union binding pocket(no: 2) in the query (biounit: 1zth.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3S43 478 0.02466 0.40601 None
2 1MJH ATP 0.01833 0.40253 None
3 4ME6 ADP 0.008415 0.41589 2.32558
4 2HGS ADP 0.02031 0.40193 2.32558
5 5JO1 6LM 0.01442 0.40594 4.86486
6 2Y88 2ER 0.02952 0.40867 5.7377
7 1I7M PUT 0.006523 0.40529 5.97015
8 5V1B 8UY 0.01373 0.40343 6.66667
9 3EKK GS2 0.000005064 0.40191 9.68992
10 4J25 OGA 0.01539 0.40285 10.0437
11 5L6G XYP 0.01316 0.40923 11.6279
Pocket No.: 3; Query (leader) PDB : 1ZTH; Ligand: ADP; Similar sites found: 7
This union binding pocket(no: 3) in the query (biounit: 1zth.bio3) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4H4D 10E 0.006575 0.40786 2.32558
2 4FE2 ADP 0.008033 0.40386 2.7451
3 1OBD ATP 0.00628 0.40877 3.10078
4 3TPV ADE 0.001506 0.41168 4.65116
5 4QM9 CYS 0.01842 0.40187 6.35838
6 4XYM A12 0.002837 0.4019 6.52174
7 3IES M24 0.01673 0.41656 8.91473
Pocket No.: 4; Query (leader) PDB : 1ZTH; Ligand: ADP; Similar sites found: 5
This union binding pocket(no: 4) in the query (biounit: 1zth.bio2) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3HGM ATP 0.01854 0.40229 None
2 3JRS A8S 0.02007 0.4006 2.88462
3 3ZGJ RMN 0.01487 0.40171 5.42636
4 1N62 MCN 0.04379 0.4007 7.36434
5 4LO2 GAL BGC 0.01436 0.40089 10.8527
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