Receptor
PDB id Resolution Class Description Source Keywords
1ZP9 2 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF FULL-LEGNTH A.FULGIDUS RIO1 SERINE KINA TO ATP AND MN2+ IONS. ARCHAEOGLOBUS FULGIDUS RIO1 RIOK1 SERINE KINASE PROTEIN KINASE MANGANESE RIBOSBIOGENESIS TRANSFERASE
Ref.: STRUCTURE AND ACTIVITY OF THE ATYPICAL SERINE KINAS FEBS J. V. 272 3698 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ATP A:260;
B:260;
C:260;
D:260;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
507.181 C10 H16 N5 O13 P3 c1nc(...
MN A:259;
B:259;
C:259;
D:259;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
54.938 Mn [Mn+2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZP9 2 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF FULL-LEGNTH A.FULGIDUS RIO1 SERINE KINA TO ATP AND MN2+ IONS. ARCHAEOGLOBUS FULGIDUS RIO1 RIOK1 SERINE KINASE PROTEIN KINASE MANGANESE RIBOSBIOGENESIS TRANSFERASE
Ref.: STRUCTURE AND ACTIVITY OF THE ATYPICAL SERINE KINAS FEBS J. V. 272 3698 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 1ZP9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 1ZP9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 1ZP9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ATP; Similar ligands found: 404
No: Ligand ECFP6 Tc MDL keys Tc
1 ATP 1 1
2 AQP 0.985507 1
3 5FA 0.985507 1
4 B4P 0.927536 0.971831
5 AP5 0.927536 0.971831
6 BA3 0.913043 0.971831
7 ADP 0.9 1
8 A2D 0.884058 0.971831
9 SAP 0.84 0.945946
10 AGS 0.84 0.945946
11 AN2 0.810811 0.985915
12 25L 0.809524 0.985915
13 APR 0.802632 0.971831
14 AR6 0.802632 0.971831
15 M33 0.8 0.958333
16 TAT 0.794872 0.958904
17 ACQ 0.794872 0.972222
18 AD9 0.792208 0.972222
19 ACP 0.789474 0.972222
20 A 0.788732 0.971429
21 AMP 0.788732 0.971429
22 ANP 0.772152 0.972222
23 ADX 0.753247 0.873418
24 CA0 0.753247 0.945205
25 A22 0.746988 0.985915
26 50T 0.74359 0.958333
27 APC 0.734177 0.958904
28 PRX 0.734177 0.893333
29 ABM 0.733333 0.917808
30 ATF 0.731707 0.958904
31 ITT 0.730769 0.943662
32 7D4 0.730769 0.905405
33 ADQ 0.729412 0.945205
34 AMP MG 0.72 0.891892
35 AP2 0.714286 0.958904
36 A12 0.714286 0.958904
37 A1R 0.709302 0.907895
38 SRA 0.706667 0.918919
39 5AL 0.698795 0.931507
40 OAD 0.693182 0.945205
41 ADP MG 0.6875 0.905405
42 AU1 0.6875 0.972222
43 SRP 0.682353 0.906667
44 G5P 0.680851 0.921053
45 BEF ADP 0.679012 0.881579
46 ADP BEF 0.679012 0.881579
47 25A 0.678161 0.971831
48 3OD 0.677778 0.945205
49 4AD 0.670455 0.92
50 G3A 0.670213 0.921053
51 00A 0.662921 0.883117
52 ADV 0.662651 0.932432
53 ADP PO3 0.662651 0.943662
54 RBY 0.662651 0.932432
55 BIS 0.659341 0.933333
56 5SV 0.659091 0.848101
57 8QN 0.659091 0.931507
58 OOB 0.659091 0.931507
59 GTA 0.65625 0.886076
60 ATP MG 0.654762 0.905405
61 UP5 0.653061 0.92
62 AMO 0.651685 0.932432
63 PAJ 0.651685 0.884615
64 2A5 0.650602 0.918919
65 MAP 0.647727 0.945946
66 3AT 0.647059 0.971831
67 AHX 0.644444 0.896104
68 DLL 0.644444 0.931507
69 PAP 0.642857 0.985714
70 ATR 0.642857 0.971429
71 PTJ 0.641304 0.896104
72 7D3 0.6375 0.905405
73 3UK 0.637363 0.918919
74 SON 0.634146 0.932432
75 A4P 0.633663 0.843373
76 ALF ADP 0.632184 0.87013
77 ADP ALF 0.632184 0.87013
78 LAD 0.630435 0.860759
79 WAQ 0.630435 0.883117
80 PR8 0.630435 0.85
81 AFH 0.628866 0.884615
82 DTP 0.627907 0.905405
83 GAP 0.627907 0.893333
84 ANP MG 0.625 0.894737
85 VO4 ADP 0.625 0.931507
86 ADP VO4 0.625 0.931507
87 1ZZ 0.623656 0.839506
88 TXA 0.623656 0.932432
89 FYA 0.623656 0.905405
90 ME8 0.623656 0.839506
91 NB8 0.623656 0.896104
92 T5A 0.621359 0.841463
93 RAB 0.619718 0.84507
94 ADN 0.619718 0.84507
95 XYA 0.619718 0.84507
96 9SN 0.610526 0.871795
97 48N 0.61 0.896104
98 AP0 0.607843 0.896104
99 FA5 0.604167 0.906667
100 YAP 0.604167 0.894737
101 TXD 0.60396 0.907895
102 6V0 0.60396 0.896104
103 NXX 0.60396 0.932432
104 NAI 0.60396 0.907895
105 DND 0.60396 0.932432
106 NAX 0.60396 0.873418
107 ADP BMA 0.602151 0.918919
108 A2R 0.6 0.985915
109 OMR 0.598039 0.851852
110 TXE 0.598039 0.907895
111 XAH 0.597938 0.839506
112 DAL AMP 0.593407 0.905405
113 7DT 0.593023 0.985714
114 AOC 0.592593 0.821918
115 4UV 0.591837 0.894737
116 DDS 0.590909 0.878378
117 139 0.590476 0.873418
118 CNA 0.584906 0.932432
119 6AD 0.58427 0.909091
120 5AS 0.583333 0.77907
121 5N5 0.581081 0.819444
122 4UU 0.58 0.894737
123 4TC 0.576923 0.896104
124 ADJ 0.575472 0.851852
125 5CD 0.573333 0.805556
126 A4D 0.573333 0.819444
127 RGT 0.571429 0.958904
128 A3P 0.571429 0.971429
129 7D5 0.56962 0.878378
130 LAQ 0.568627 0.839506
131 YLP 0.563107 0.819277
132 A A 0.5625 0.944444
133 UPA 0.561905 0.907895
134 AV2 0.56044 0.917808
135 COD 0.559633 0.811765
136 4UW 0.557692 0.860759
137 JB6 0.556701 0.883117
138 3AM 0.555556 0.929577
139 ATP A A A 0.555556 0.930556
140 A2P 0.552941 0.957143
141 TYM 0.552381 0.906667
142 NA7 0.552083 0.958904
143 EP4 0.551282 0.753247
144 MYR AMP 0.55102 0.817073
145 PPS 0.549451 0.873418
146 YLB 0.54717 0.819277
147 YLC 0.54717 0.839506
148 NAD 0.545455 0.931507
149 DAT 0.545455 0.905405
150 G5A 0.544444 0.77907
151 M2T 0.544304 0.734177
152 DTA 0.544304 0.786667
153 3DH 0.54321 0.773333
154 128 0.542857 0.776471
155 AHZ 0.538462 0.817073
156 SSA 0.537634 0.8
157 GTP 0.537634 0.92
158 MTA 0.5375 0.773333
159 IOT 0.537037 0.831325
160 A3D 0.535714 0.918919
161 TYR AMP 0.534653 0.881579
162 AR6 AR6 0.533981 0.917808
163 7MD 0.533981 0.8625
164 YLA 0.53211 0.819277
165 AMP DBH 0.529412 0.893333
166 IMO 0.529412 0.929577
167 TAD 0.528846 0.884615
168 AYB 0.527273 0.809524
169 A5A 0.526882 0.807229
170 TSB 0.526316 0.819277
171 EAD 0.525424 0.873418
172 2AM 0.52439 0.943662
173 6RE 0.52381 0.759494
174 7DD 0.522727 0.985714
175 V3L 0.521739 0.971831
176 AVV 0.520833 0.896104
177 BTX 0.517857 0.841463
178 NAE 0.517241 0.894737
179 54H 0.515789 0.788235
180 VMS 0.515789 0.788235
181 52H 0.515789 0.77907
182 NSS 0.515464 0.8
183 BT5 0.513274 0.831325
184 NAQ 0.512821 0.871795
185 ZAS 0.511905 0.766234
186 A3N 0.511628 0.786667
187 J7C 0.511628 0.769231
188 5X8 0.511111 0.763158
189 53H 0.510417 0.77907
190 5CA 0.510417 0.8
191 ARU 0.510204 0.860759
192 ARG AMP 0.509434 0.829268
193 AF3 ADP 3PG 0.509259 0.8375
194 LA8 ALF 3PG 0.509259 0.8375
195 ALF ADP 3PG 0.509259 0.8375
196 ZID 0.508475 0.918919
197 P1H 0.508197 0.851852
198 OVE 0.505882 0.905405
199 S4M 0.505747 0.666667
200 LPA AMP 0.504673 0.817073
201 7MC 0.504587 0.841463
202 DZD 0.5 0.884615
203 LSS 0.5 0.761364
204 DSZ 0.5 0.8
205 P5A 0.5 0.744444
206 DSH 0.5 0.725
207 FB0 0.5 0.804598
208 MAO 0.5 0.759036
209 NDE 0.495935 0.932432
210 N0B 0.495798 0.819277
211 M24 0.495726 0.85
212 YLY 0.495726 0.809524
213 NJP 0.495575 0.945946
214 NVA LMS 0.494949 0.761364
215 MGP 0.494737 0.884615
216 6C6 0.494624 0.881579
217 NAJ PZO 0.491379 0.848101
218 0WD 0.491228 0.921053
219 LEU LMS 0.49 0.761364
220 6G0 0.489583 0.884615
221 GJV 0.488636 0.75
222 6FA 0.488189 0.841463
223 5AD 0.486842 0.746479
224 GSU 0.485149 0.77907
225 KAA 0.485149 0.752809
226 71V 0.483146 0.907895
227 NEC 0.482759 0.746667
228 A3G 0.482759 0.8
229 NAD IBO 0.482456 0.87013
230 ODP 0.482456 0.909091
231 FAS 0.48062 0.851852
232 FAD 0.48062 0.851852
233 7D7 0.480519 0.743243
234 FDA 0.480315 0.833333
235 N6P 0.48 0.915493
236 2SA 0.479167 0.932432
237 GP3 0.478723 0.921053
238 4TA 0.478261 0.807229
239 G A A A 0.478261 0.871795
240 SFG 0.478261 0.75
241 NPW 0.477876 0.886076
242 NDP 0.477876 0.921053
243 NDC 0.47619 0.871795
244 YSA 0.47619 0.77907
245 MGO 0.474227 0.860759
246 6IA 0.473684 0.8375
247 TXP 0.473684 0.921053
248 GDP 0.473684 0.92
249 NZQ 0.473684 0.909091
250 A7D 0.472527 0.776316
251 SFD 0.469231 0.734043
252 ZDA 0.468085 0.864865
253 SA8 0.468085 0.707317
254 A5D 0.468085 0.786667
255 12D 0.46789 0.785714
256 PGS 0.467391 0.883117
257 MHZ 0.467391 0.697674
258 62F 0.466165 0.8625
259 DA 0.465909 0.878378
260 D5M 0.465909 0.878378
261 GGZ 0.464646 0.825
262 SAH 0.463158 0.74359
263 SAI 0.463158 0.734177
264 NAJ PYZ 0.46281 0.85
265 FAY 0.462687 0.8625
266 Y3J 0.4625 0.726027
267 PO4 PO4 A A A A PO4 0.460784 0.902778
268 AAM 0.460674 0.971429
269 RFL 0.459259 0.821429
270 SMM 0.459184 0.686047
271 AMZ 0.458824 0.916667
272 C2R 0.458824 0.90411
273 SAM 0.458333 0.690476
274 A3S 0.456522 0.810811
275 FNK 0.455224 0.804598
276 7C5 0.453704 0.818182
277 AAT 0.453608 0.707317
278 EEM 0.453608 0.690476
279 XNP 0.452991 0.873418
280 AIR 0.451219 0.901408
281 62X 0.45098 0.666667
282 GSP 0.45 0.873418
283 ETB 0.45 0.833333
284 DCA 0.45 0.823529
285 U A G G 0.449153 0.883117
286 NIA 0.448276 0.822785
287 AMP NAD 0.447154 0.881579
288 A3T 0.446809 0.821918
289 K15 0.446602 0.682353
290 A A A 0.446602 0.905405
291 PUA 0.446281 0.884615
292 6K6 0.445545 0.930556
293 GEK 0.445545 0.7375
294 4YB 0.445455 0.761364
295 S7M 0.444444 0.690476
296 DG1 0.443548 0.921053
297 1DG 0.443548 0.921053
298 Z5A 0.443548 0.77907
299 COA 0.442623 0.823529
300 0T1 0.442623 0.823529
301 WSA 0.442478 0.788235
302 8BR 0.43956 0.906667
303 101 0.438202 0.878378
304 IDP 0.4375 0.918919
305 NAP 0.435484 0.945205
306 APU 0.434783 0.894737
307 A U 0.434783 0.87013
308 7RP 0.433333 0.928571
309 A6D 0.432692 0.722892
310 CAO 0.432 0.795455
311 AMX 0.432 0.833333
312 COS 0.432 0.804598
313 TAP 0.432 0.907895
314 J7V 0.432 0.833333
315 30N 0.432 0.752688
316 V1N 0.431193 0.917808
317 649 0.429825 0.744444
318 P5F 0.429577 0.823529
319 NA0 0.428571 0.932432
320 CMX 0.428571 0.823529
321 7RA 0.428571 0.957747
322 SCO 0.428571 0.823529
323 0UM 0.427184 0.698795
324 GAV 0.427184 0.884615
325 ACK 0.426966 0.861111
326 1RB 0.426966 0.885714
327 QQY 0.426966 0.815789
328 GCP 0.425743 0.896104
329 G1R 0.425743 0.907895
330 FAM 0.425197 0.804598
331 FCX 0.425197 0.795455
332 ACO 0.425197 0.795455
333 GNH 0.424242 0.907895
334 F2N 0.423611 0.813953
335 GDC 0.422018 0.884615
336 GDD 0.422018 0.884615
337 GKE 0.422018 0.884615
338 HAX 0.421875 0.804598
339 3AD 0.421687 0.805556
340 GNP 0.421569 0.896104
341 FA9 0.42069 0.864198
342 KB1 0.420561 0.698795
343 TM1 0.420561 0.77381
344 H6Y 0.42 0.945205
345 2MC 0.419847 0.769231
346 3KK 0.418605 0.804598
347 FYN 0.418605 0.823529
348 S8M 0.417476 0.759494
349 2VA 0.416667 0.8
350 NHD 0.416667 0.905405
351 26A 0.416667 0.763158
352 QQX 0.41573 0.805195
353 SOP 0.415385 0.804598
354 OXK 0.415385 0.804598
355 COK 0.415385 0.804598
356 MCD 0.415385 0.804598
357 CA6 0.415385 0.729167
358 YE1 0.413534 0.813953
359 FAI 0.413043 0.916667
360 AS 0.413043 0.833333
361 RMB 0.413043 0.873239
362 1VU 0.412214 0.795455
363 CO6 0.412214 0.804598
364 CMC 0.412214 0.804598
365 NMX 0.412214 0.76087
366 SXZ 0.411215 0.710843
367 ANZ 0.410714 0.8
368 SCA 0.410448 0.804598
369 PLP AAD 0.409836 0.741573
370 SCD 0.409091 0.823529
371 CAJ 0.409091 0.804598
372 NAD BBN 0.408759 0.841463
373 NVA 2AD 0.408163 0.74359
374 D3Y 0.407767 0.789474
375 CC5 0.407407 0.816901
376 U G A 0.407407 0.839506
377 KH3 0.40708 0.674419
378 SLU 0.406504 0.770115
379 G 0.40625 0.906667
380 5GP 0.40625 0.906667
381 BCO 0.406015 0.804598
382 IVC 0.406015 0.813953
383 A1S 0.406015 0.804598
384 MLC 0.406015 0.804598
385 3HC 0.406015 0.813953
386 1HE 0.406015 0.786517
387 GTG 0.405405 0.886076
388 NMN AMP PO4 0.404959 0.87013
389 3D1 0.404762 0.773333
390 3L1 0.404762 0.773333
391 CMP 0.404255 0.901408
392 2BA 0.404255 0.915493
393 SO8 0.40404 0.789474
394 VRT 0.40404 0.769231
395 MCA 0.402985 0.795455
396 CAA 0.402985 0.813953
397 COO 0.402985 0.804598
398 NAD CJ3 0.402878 0.811765
399 G2R 0.401869 0.884615
400 3NZ 0.401869 0.782051
401 ZZB 0.4 0.77381
402 MC4 0.4 0.76087
403 2FA 0.4 0.813333
404 2CP 0.4 0.795455
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZP9; Ligand: ATP; Similar sites found: 333
This union binding pocket(no: 1) in the query (biounit: 1zp9.bio3) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4NS0 PIO 0.01805 0.40444 None
2 4U98 ACP 0.00007874 0.48249 1.16279
3 5LI1 ANP 0.0000001773 0.62812 1.93798
4 3MVH WFE 0.0000005396 0.62263 1.93798
5 2PUL ACP 0.000001965 0.55098 1.93798
6 4OCJ NDG 0.00008477 0.52805 1.93798
7 3SLS ANP 0.00001696 0.47394 1.93798
8 3VPC ADP 0.0002377 0.43133 1.93798
9 2JDR L20 0.000003128 0.61984 2.32558
10 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.000003128 0.61984 2.32558
11 3TXO 07U 0.0000006995 0.58498 2.32558
12 4YMJ 4EJ 0.000006481 0.58012 2.32558
13 5UIU 8CG 0.000005639 0.57376 2.32558
14 5IH9 6BF 0.00001086 0.5688 2.32558
15 5EW9 5VC 0.0001673 0.55749 2.32558
16 5JGA 6KC 0.0000466 0.53318 2.32558
17 4G17 0VN 0.00001339 0.52727 2.32558
18 4Y0X ADP 0.00001723 0.52235 2.32558
19 1K3A ACP 0.00002303 0.50778 2.32558
20 5LXM ADP 0.00007439 0.49654 2.32558
21 5T8O 76Z 0.00001812 0.48103 2.32558
22 3NW7 LGV 0.001313 0.47722 2.32558
23 2PZI AXX 0.0004259 0.46503 2.32558
24 3E5A VX6 0.0002637 0.41901 2.32558
25 4H4D 10E 0.008067 0.40605 2.32558
26 5W2I I3P 0.0000348 0.52614 2.33463
27 5W2I ADP 0.0000348 0.52614 2.33463
28 3MTX PGT 0.02889 0.40225 2.64901
29 2GU8 796 0.0000009641 0.64483 2.71318
30 4WB6 ATP 0.0000003735 0.62348 2.71318
31 1RE8 BD2 0.000003988 0.60349 2.71318
32 1O9U ADZ 0.000004714 0.60182 2.71318
33 5X8I SQZ 0.0000005733 0.59557 2.71318
34 4OTH DRN 0.000002718 0.57309 2.71318
35 5JFS 6K0 0.00003235 0.55144 2.71318
36 5DEY 59T 0.00007181 0.54712 2.71318
37 4CYI ATP 0.0000236 0.5271 2.71318
38 2F57 23D 0.00009971 0.48803 2.71318
39 3LXK MI1 0.0000113 0.44545 2.71318
40 3X01 AMP 0.003476 0.43881 2.71318
41 4WB7 ATP 0.00000262 0.41888 2.71318
42 4FE2 ADP 0.007044 0.40877 2.7451
43 3V8S 0HD 0.0000004434 0.59736 3.10078
44 2F2U M77 0.000004738 0.56313 3.10078
45 2IF8 ADP 0.0000181 0.55173 3.10078
46 3PLS ANP 0.000005808 0.54673 3.10078
47 5FBN 5WF 0.00008346 0.52406 3.10078
48 5UOX 8GY 0.00003785 0.51999 3.10078
49 4Y93 746 0.0001069 0.50527 3.10078
50 2R5T ANP 0.00002347 0.47026 3.10078
51 3FHR P4O 0.00009467 0.4602 3.10078
52 3WVR AMP 0.000472 0.45764 3.10078
53 1IA9 ANP 0.0001505 0.45708 3.10078
54 4OYA 1VE 0.006646 0.45431 3.10078
55 3H9R TAK 0.0001817 0.45272 3.10078
56 4NW6 2NS 0.000002292 0.44502 3.10078
57 3TII ANP 0.001139 0.43044 3.10078
58 5HX8 66P 0.00007626 0.43021 3.10078
59 1OBD ATP 0.008991 0.40387 3.10078
60 5BVE 4VG 0.000004589 0.61556 3.48837
61 4N70 2HX 0.000003621 0.60822 3.48837
62 5LPZ ADP 0.0000004377 0.60092 3.48837
63 4L3L 5FI 0.000001756 0.59806 3.48837
64 3F7Z 34O 0.0000009239 0.58612 3.48837
65 5I35 ANP 0.000001095 0.57957 3.48837
66 3QCQ 3Q0 0.00004709 0.57916 3.48837
67 3ZRM ZRM 0.000001341 0.57873 3.48837
68 3CY2 MB9 0.000002429 0.57791 3.48837
69 3TKI S25 0.00002415 0.5712 3.48837
70 2V7O DRN 0.0000003656 0.56563 3.48837
71 2XK9 XK9 0.00002117 0.55464 3.48837
72 5MW8 ATP 0.000008282 0.55305 3.48837
73 4OH4 ANP 0.00000186 0.53864 3.48837
74 5HES 032 0.00001616 0.53716 3.48837
75 5LPB ADP 0.000004502 0.52836 3.48837
76 2VN9 GVD 0.00000802 0.50756 3.48837
77 5LVP ATP 0.00002495 0.50689 3.48837
78 2HY0 306 0.00005543 0.50587 3.48837
79 2VZ6 FEF 0.00007884 0.49881 3.48837
80 5DBX ANP 0.0000452 0.49518 3.48837
81 4NM5 ADP 0.002804 0.46436 3.48837
82 4E1Z 0MX 0.000052 0.45297 3.48837
83 2JLD AG1 0.000000689 0.45082 3.48837
84 4QTB 38Z 0.00001319 0.44111 3.48837
85 3G5D 1N1 0.000002244 0.62608 3.87597
86 2B9H ADP 0.0000002346 0.61648 3.87597
87 2B9F ADP 0.0000002272 0.61391 3.87597
88 2YAK OSV 0.000001513 0.60116 3.87597
89 2B9J ADP 0.0000001692 0.59717 3.87597
90 5LXC 7AA 0.000001007 0.57785 3.87597
91 4H3Q ANP 0.000002455 0.5777 3.87597
92 2B9I ADP 0.0000003006 0.57269 3.87597
93 4WNK 453 0.000006181 0.57186 3.87597
94 4CLI 5P8 0.00001703 0.5693 3.87597
95 2H8H H8H 0.000005517 0.55072 3.87597
96 1PHK ATP 0.000009416 0.54289 3.87597
97 2X2M X2M 0.00001528 0.53828 3.87597
98 4H3P ANP 0.00001182 0.53562 3.87597
99 3DAK ANP 0.00001666 0.52301 3.87597
100 4IX4 ADP 0.0000747 0.504 3.87597
101 3HZT J60 0.0001243 0.49604 3.87597
102 1Y57 MPZ 0.000005766 0.4809 3.87597
103 3PDT ADP 0.000157 0.47916 3.87597
104 4ZS4 ATP 0.00005081 0.47381 3.87597
105 3ALN ANP 0.00004564 0.46498 3.87597
106 4UWH JXM 0.001636 0.43333 3.87597
107 2IO8 ADP 0.0007929 0.40453 3.87597
108 1GPM AMP 0.03583 0.40347 3.87597
109 4DFU QUE 0.01813 0.40188 3.87597
110 4IJP 1EH 0.0000008761 0.59313 4.26357
111 1Q8Y ADP 0.000003945 0.56297 4.26357
112 1ZY5 ANP 0.00001705 0.52553 4.26357
113 1Q8Y ADE 0.000004774 0.52039 4.26357
114 1W2D ADP 0.00004963 0.51489 4.26357
115 5BYZ 4WE 0.00014 0.50852 4.26357
116 5C03 AGS 0.00007513 0.49898 4.26357
117 4OUC 5ID 0.0001429 0.481 4.26357
118 4WOV 3SM 0.0002823 0.47327 4.26357
119 5HVJ ANP 0.0008458 0.46905 4.26357
120 1TZD ADP 0.000003133 0.463 4.26357
121 2VPQ ANP 0.0008653 0.45883 4.26357
122 4KS7 X4Z 0.00003739 0.4543 4.26357
123 3ETH ATP 0.001303 0.44865 4.26357
124 2Q7D ANP 0.002028 0.44664 4.26357
125 2QLU ADE 0.003197 0.44042 4.26357
126 4E93 GUI 0.000007819 0.42266 4.26357
127 1W2D 4IP 0.0003211 0.4 4.26357
128 5L8L ADP 0.000202 0.46119 4.2735
129 4RFR RHN 0.009371 0.4052 4.4335
130 1W6P NDG GAL 0.00395 0.445 4.47761
131 4YLL 4E3 0.00000514 0.56272 4.65116
132 3M2W L8I 0.000004183 0.54047 4.65116
133 4ASE AV9 0.00003453 0.53235 4.65116
134 4BHN BH9 0.00002261 0.52797 4.65116
135 5CEO 50D 0.0000703 0.5003 4.65116
136 5W4W 9WG 0.000212 0.49984 4.65116
137 2RIO ADP 0.00004378 0.49259 4.65116
138 5DH3 5BS 0.0001681 0.48774 4.65116
139 3DNT ATP 0.0007669 0.46314 4.65116
140 4KBA 1QM 0.0000287 0.42863 4.65116
141 3TPV ADE 0.001292 0.41823 4.65116
142 3KCC CMP 0.01128 0.4015 4.65116
143 3IDB ANP 0.000002095 0.49667 4.96894
144 1VJY 460 0.000007876 0.57049 5.03876
145 5EOB 5QQ 0.0000438 0.55909 5.03876
146 4TWP AXI 0.00004313 0.55042 5.03876
147 4K33 ACP 0.000006769 0.54947 5.03876
148 4I94 ANP 0.000012 0.53245 5.03876
149 2WQN ADP 0.00002142 0.52492 5.03876
150 4AUA 4AU 0.0009743 0.4459 5.03876
151 4BKJ STI 0.00208 0.44449 5.03876
152 4AT0 FAD 0.008988 0.43867 5.03876
153 3VOT ADP 0.001022 0.43268 5.03876
154 2A19 ANP 0.000001089 0.59332 5.14286
155 4XV1 904 0.000002023 0.60087 5.42636
156 4YZN 4K5 0.000003532 0.57032 5.42636
157 2PVF ACP 0.000002047 0.55184 5.42636
158 2HK5 1BM 0.000009519 0.54531 5.42636
159 3DLS ADP 0.000005894 0.54332 5.42636
160 3RI1 3RH 0.00002168 0.53997 5.42636
161 4P5Z Q7M 0.00006155 0.53488 5.42636
162 1OUK 084 0.0004757 0.53285 5.42636
163 1BYG STU 0.00001063 0.5318 5.42636
164 5LI9 ACP 0.000003816 0.51772 5.42636
165 5UR1 YY9 0.0004182 0.49882 5.42636
166 4DC2 ADE 0.000001649 0.49119 5.42636
167 5MJA 7O3 0.0001007 0.48783 5.42636
168 4CQE CQE 0.000004442 0.48757 5.42636
169 3GC8 B45 0.00004022 0.45752 5.42636
170 2Y6O 1N1 0.00006031 0.44924 5.42636
171 2R7K AMZ 0.002347 0.4467 5.42636
172 4LOO SB4 0.000357 0.44575 5.42636
173 3VRY B43 0.00002376 0.44254 5.42636
174 2R85 AMP 0.01172 0.41584 5.42636
175 3VHE 42Q 0.0000795 0.40228 5.42636
176 2QCS ANP 0.0000003815 0.62304 5.81395
177 3KRR DQX 0.00003071 0.57478 5.81395
178 5EFQ ADP 0.000003163 0.56174 5.81395
179 5U6C 7YS 0.00000845 0.55022 5.81395
180 5GZ9 ANP 0.00001322 0.54357 5.81395
181 3UIM ANP 0.00001872 0.52652 5.81395
182 3GGF GVD 0.00001794 0.52156 5.81395
183 2XVD AS6 0.00008956 0.51445 5.81395
184 4FG8 ATP 0.000003796 0.51048 5.81395
185 4ANW O92 0.0009068 0.47088 5.81395
186 2AQX ATP 0.0004645 0.46944 5.81395
187 4D4U FUC GAL 0.02212 0.40631 5.81395
188 3V4S ATP 0.001637 0.4005 5.81395
189 5ML3 DL3 0.01797 0.41351 6.04027
190 4UAL 3FV 0.0000009183 0.58624 6.20155
191 4BTK DTQ 0.000004048 0.55685 6.20155
192 4OCV ANP 0.00001465 0.53408 6.20155
193 4A4X JUP 0.00004671 0.52419 6.20155
194 4NFN 2KC 0.00001773 0.51079 6.20155
195 3IGO ANP 0.000001891 0.50888 6.20155
196 1GSA ADP 0.0001191 0.49903 6.20155
197 5EKO N17 0.0003912 0.47492 6.20155
198 3AQV TAK 0.0008181 0.45167 6.20155
199 4EWH T77 0.00003888 0.43122 6.20155
200 3C1X CKK 0.00092 0.40659 6.20155
201 4XYM A12 0.005189 0.41703 6.52174
202 1XJD STU 0.000001038 0.58684 6.58915
203 2PYW ADP 0.00000008448 0.56682 6.58915
204 4NST ADP 0.000002764 0.56441 6.58915
205 5TA6 79D 0.00002092 0.5427 6.58915
206 5USZ SKE 0.00005748 0.52182 6.58915
207 3AKK ADP 0.0003896 0.46868 6.58915
208 4CSV STI 0.0006474 0.46471 6.58915
209 3KRL KRL 0.0006771 0.46184 6.58915
210 4I6H 1C8 0.0004806 0.44109 6.58915
211 4GJ3 0XP 0.00000635 0.57318 6.97674
212 4EUU BX7 0.00001956 0.54209 6.97674
213 5DA3 58V 0.00003764 0.52057 6.97674
214 3LXN MI1 0.000005392 0.50418 6.97674
215 5H2U 1N1 0.00009793 0.49373 6.97674
216 3VPD ANP 0.0008553 0.45713 6.97674
217 2VQD AP2 0.001633 0.40795 6.97674
218 2WEL K88 0.00004877 0.4563 7.33333
219 5M06 ADP 0.00002194 0.51762 7.36434
220 3SXS PP2 0.00007925 0.45394 7.36434
221 1IOW ADP 0.01095 0.42085 7.36434
222 1IOW PHY 0.01095 0.42085 7.36434
223 1AUX AGS 0.002214 0.41475 7.36434
224 5K2M ADP 0.0003225 0.48078 7.54717
225 2X4Z X4Z 0.00001205 0.56496 7.75194
226 4XH0 ADP 0.00001536 0.56032 7.75194
227 4JDI ANP 0.000006728 0.49669 7.75194
228 4O4F ATP 0.0006379 0.4687 8.06452
229 4O4F IHP 0.0006942 0.4687 8.06452
230 3PVW QRX 0.00001578 0.44873 8.10811
231 3UDZ ADP 0.000008484 0.54497 8.13953
232 4WNP 3RJ 0.000004345 0.54079 8.13953
233 4O1P ANP 0.000009733 0.53947 8.13953
234 2OFV 242 0.00009069 0.52378 8.13953
235 1U59 STU 0.00002075 0.49957 8.13953
236 5C4L 4XR 0.0004504 0.48408 8.13953
237 5C4L SIS 0.0005315 0.48062 8.13953
238 4ZGP ADP 0.002749 0.42547 8.13953
239 2GQS ADP 0.003146 0.42281 8.43882
240 2GQR ADP 0.005009 0.41364 8.43882
241 5EYK 5U5 0.0004512 0.47927 8.47458
242 5TDF ADP 0.003626 0.42613 8.52713
243 3W0O HY0 0.00004948 0.41816 8.52713
244 3W0O ADP 0.00004948 0.41816 8.52713
245 4YZC STU 0.000003578 0.594 8.91473
246 4M69 ANP 0.00001469 0.53661 8.91473
247 4XLI 1N1 0.00004789 0.50521 8.91473
248 5VZ0 ADP 0.000278 0.47059 8.91473
249 3Q60 ATP 0.0007347 0.45146 8.91473
250 4Y85 499 0.001061 0.44422 8.91473
251 3K5I ADP 0.002741 0.40176 8.91473
252 5A6N U7E 0.0000009221 0.5892 9.30233
253 4X7Q 3YR 0.000003115 0.5313 9.30233
254 2Z7R STU 0.00000135 0.51532 9.30233
255 4L9I 8PR 0.00007226 0.49711 9.30233
256 4MV1 ADP 0.015 0.41185 9.30233
257 5UKL SIX 0.000002283 0.58844 9.67742
258 2YAB AMP 0.0000009532 0.58854 9.68992
259 5N87 N66 0.00001908 0.55684 9.68992
260 5DMZ ADP 0.000001433 0.54631 9.68992
261 3BU5 ATP 0.00001731 0.52806 9.68992
262 3C0G 3AM 0.00001674 0.51425 9.68992
263 4AU8 Z3R 0.00006669 0.50882 9.68992
264 4R78 AMP 0.0001108 0.5052 9.68992
265 3EKK GS2 0.00001504 0.40366 9.68992
266 3FHI ANP 0.0000004541 0.61946 9.74026
267 4JR7 GNP 0.000001393 0.57798 10.0775
268 5CKW ANP 0.000002165 0.54457 10.0775
269 2WU6 DKI 0.000001342 0.50567 10.0775
270 3PP0 03Q 0.00002467 0.43712 10.0775
271 2XMY CDK 0.00003999 0.56972 10.4651
272 4CFU 2WC 0.00000871 0.53568 10.4651
273 5VC5 96M 0.00005012 0.52465 10.4651
274 4BCN T9N 0.00002323 0.52329 10.4651
275 4BCQ TJF 0.00006469 0.50945 10.4651
276 4IDT T28 0.00002525 0.50478 10.4651
277 4U0I 0LI 0.0001814 0.5031 10.4651
278 2WEI VGG 0.0001739 0.47716 10.4651
279 4BCM T7Z 0.0001236 0.45097 10.4651
280 5LMK 6ZK 0.0008524 0.44608 10.4651
281 5MY8 RXZ 0.000002888 0.57917 10.8527
282 2ZV2 609 0.000002249 0.57843 10.8527
283 4OAV ACP 0.000006922 0.54328 10.8527
284 1V0O INR 0.00001978 0.48913 10.8527
285 2PVN P63 0.000001451 0.46659 10.8527
286 3GQI ACP 0.0000237 0.49641 11.0619
287 5G1X ADP 0.0001279 0.48587 11.1111
288 3PE2 E1B 0.000007635 0.58935 11.2403
289 3OFM 4B0 0.000004133 0.54034 11.2403
290 3TDV GDP 0.0000393 0.48645 11.2403
291 3ORK AGS 0.000005846 0.4709 11.2403
292 4C2V YJA 0.0009735 0.46649 11.3636
293 4C2W ANP 0.0001077 0.47222 11.5385
294 4CRL C1I 0.000007485 0.57332 11.6279
295 4WHZ 3NL 0.0001147 0.53257 11.6279
296 4UX9 ANP 0.000003607 0.50862 11.6279
297 4USF 6UI 0.0001556 0.49564 11.6279
298 4IZY 1J2 0.000008718 0.49078 11.6279
299 3E7O 35F 0.0007376 0.47522 11.6279
300 5JKG 6LF 0.003608 0.44794 11.6279
301 3TTI KBI 0.00002001 0.43725 11.6279
302 3PTG 932 0.001498 0.42166 11.6279
303 4F9C 0SX 0.0000008298 0.56702 12.4031
304 4U44 3D9 0.000005072 0.55238 12.4031
305 5IQD GNP 0.00003875 0.54331 12.4031
306 5IQD RIO 0.00004149 0.54331 12.4031
307 3SRV S19 0.0000004963 0.59515 12.7907
308 4F4P 0SB 0.00004509 0.56242 12.7907
309 2BKK ADP 0.00003434 0.50159 12.7907
310 4FL3 ANP 0.000004353 0.49397 12.7907
311 3HMO STU 0.0001044 0.47686 12.7907
312 4D2S DYK 0.0002146 0.46521 12.7907
313 4LRJ ANP 0.0001281 0.47534 13.0178
314 4WW7 AMP 0.0000002246 0.62336 13.1783
315 5AX9 4KT 0.00001386 0.53247 13.1783
316 2J7T 274 0.0008115 0.47028 13.1783
317 5TO8 7FM 0.0001442 0.51804 13.5659
318 1UNH IXM 0.00001918 0.51199 13.5659
319 5AWM ANP 0.00001714 0.50555 13.9535
320 5HCY 60D 0.00002801 0.55853 14.3411
321 4Y8D 49J 0.000001511 0.54183 14.7287
322 5JZJ AN2 0.000001723 0.57064 15.1163
323 3KN5 ANP 0.0001949 0.46887 15.1163
324 4AZW ATP 0.00005264 0.51102 15.5039
325 3SXF BK5 0.00001957 0.55471 18.2171
326 3O0G 3O0 0.00002328 0.51941 18.7919
327 4BFM ANP 0.0000004195 0.5471 18.9922
328 2CSN CKI 0.0000002722 0.62998 20.5426
329 4Q5H ANP 0.000001828 0.54056 21.2644
330 2UYN 2KT 0.009826 0.41222 21.7054
331 5VCV 1N1 0.000003164 0.57498 22.8682
332 3VPB ADP 0.0002127 0.41684 23.2143
333 5HQ0 LZ9 0.000001215 0.58658 34.5238
Pocket No.: 2; Query (leader) PDB : 1ZP9; Ligand: ATP; Similar sites found: 14
This union binding pocket(no: 2) in the query (biounit: 1zp9.bio2) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5MN0 A8S 0.007456 0.40199 1.93798
2 5NCY 8TK 0.0001065 0.41366 2.32558
3 4AT3 LTI 0.0002455 0.40095 2.32558
4 4I90 CHT 0.02577 0.40082 2.32558
5 3AVR OGA 0.02148 0.40205 2.71318
6 5DXT 5H5 0.003748 0.41942 4.26357
7 1I7L ATP 0.0007354 0.40776 4.26357
8 5JO1 6LM 0.01055 0.40101 4.86486
9 2HZQ STR 0.02027 0.40361 6.89655
10 5FI4 5XV 0.002782 0.43263 8.13953
11 1N5S ADL 0.008247 0.40005 9.82143
12 4J25 OGA 0.02052 0.40271 10.0437
13 3OCP CMP 0.01445 0.4003 12.2302
14 1PK8 ATP 0.0007049 0.40275 14.7287
Pocket No.: 3; Query (leader) PDB : 1ZP9; Ligand: ATP; Similar sites found: 6
This union binding pocket(no: 3) in the query (biounit: 1zp9.bio4) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2FXD DR7 0.01918 0.40423 2.0202
2 1EWJ BLM 0.0232 0.40022 2.38095
3 2XZ9 PYR 0.01941 0.40119 2.71318
4 3ZGJ RMN 0.01506 0.40593 5.42636
5 2Y88 2ER 0.03143 0.40043 5.7377
6 1M0W ANP 0.006858 0.40526 10.0775
Pocket No.: 4; Query (leader) PDB : 1ZP9; Ligand: ATP; Similar sites found: 8
This union binding pocket(no: 4) in the query (biounit: 1zp9.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4ME6 ADP 0.01022 0.41833 2.32558
2 2YW2 ATP 0.003111 0.40095 3.10078
3 5NKB 8ZT 0.000003652 0.40205 6.20155
4 5LXT ACP 0.001884 0.40032 6.29371
5 3FC2 IBI 0.04815 0.40738 6.58915
6 3IES M24 0.01594 0.41053 8.91473
7 2YRX AMP 0.0007922 0.4019 9.68992
8 4LO2 GAL BGC 0.01889 0.40261 10.8527
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