Receptor
PDB id Resolution Class Description Source Keywords
1ZOY 2.4 Å EC: 1.3.5.1 CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY COMPLEX II FROM PORCINE HEART AT 2.4 ANGSTROMS SUS SCROFA SUCCINATE UBIQUINONE OXIDOREDUCTASE MITOCHONDRIAL RESPIRATORY COMPLEX II MEMBRANE PROTEIN STRUCTURE
Ref.: CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY MEMBRANE PROTEIN COMPLEX II CELL(CAMBRIDGE,MASS.) V. 121 1043 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EPH D:1306;
D:1307;
Invalid;
Invalid;
none;
none;
submit data
709.933 C39 H68 N O8 P CCCC=...
F3S B:304;
Part of Protein;
none;
submit data
295.795 Fe3 S4 S1[Fe...
FAD A:700;
Part of Protein;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
FES B:302;
Part of Protein;
none;
submit data
175.82 Fe2 S2 S1[Fe...
HEM C:1305;
Part of Protein;
none;
submit data
616.487 C34 H32 Fe N4 O4 Cc1c2...
SF4 B:303;
Part of Protein;
none;
submit data
351.64 Fe4 S4 [S]12...
UQ1 B:1201;
Valid;
none;
submit data
250.29 C14 H18 O4 CC1=C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZOY 2.4 Å EC: 1.3.5.1 CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY COMPLEX II FROM PORCINE HEART AT 2.4 ANGSTROMS SUS SCROFA SUCCINATE UBIQUINONE OXIDOREDUCTASE MITOCHONDRIAL RESPIRATORY COMPLEX II MEMBRANE PROTEIN STRUCTURE
Ref.: CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY MEMBRANE PROTEIN COMPLEX II CELL(CAMBRIDGE,MASS.) V. 121 1043 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
5 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
5 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: UQ1; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 UQ1 1 1
2 UQ2 0.653061 0.84375
3 UQ 0.603774 0.794118
4 UQ9 0.603774 0.794118
5 UQ5 0.603774 0.818182
6 UQ8 0.603774 0.794118
7 U10 0.603774 0.794118
8 UQ7 0.603774 0.794118
9 DCQ 0.4 0.742857
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZOY; Ligand: UQ1; Similar sites found: 102
This union binding pocket(no: 1) in the query (biounit: 1zoy.bio1) has 12 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1ZDU P3A 0.03653 0.40118 2.04082
2 3OV6 MK0 0.04645 0.40269 2.91262
3 3IS2 FAD 0.003326 0.46197 3.8961
4 3D72 FAD 0.005048 0.45446 4.02685
5 3QVV 3QV 0.03724 0.41599 4.36508
6 4QJR PIZ 0.02439 0.41171 4.89796
7 3EM0 CHD 0.009146 0.45996 5.07246
8 2Z6D FMN 0.006577 0.43421 5.38462
9 3V1V GST 0.02724 0.40205 5.54273
10 5MBC FMN 0.006014 0.43264 5.55556
11 2QO4 CHD 0.02679 0.40962 5.55556
12 1M5B BN1 0.04009 0.44483 5.82524
13 4U63 FAD 0.01996 0.42096 5.82524
14 5U98 1KX 0.02655 0.43915 6.06061
15 3S43 478 0.03159 0.40601 6.06061
16 2FH5 GTP 0.02108 0.4079 6.07477
17 2Z6C FMN 0.006748 0.43307 6.20155
18 1NP7 FAD 0.01175 0.43512 6.79612
19 5B0W 22B 0.031 0.41559 6.79612
20 2BII MTV 0.03247 0.40441 6.79612
21 3P7N FMN 0.01044 0.42237 7.14286
22 3QDJ ALA ALA GLY ILE GLY ILE LEU THR VAL 0.04037 0.41227 7.14286
23 5HCY 60D 0.04351 0.41137 7.14286
24 2V1O COA 0.04 0.40029 7.28477
25 3G4G D71 0.02505 0.40276 7.53968
26 3S7O LBV 0.04231 0.4057 7.58017
27 4O4K 2PK 0.03333 0.4023 7.76699
28 4QYN RTL 0.001122 0.47249 8.27068
29 2PR5 FMN 0.002797 0.45336 8.33333
30 4WO4 JLS 0.03933 0.41468 8.33333
31 4E2J MOF 0.01629 0.41416 8.4
32 3GN8 DEX 0.01692 0.41078 8.43373
33 1KSH GDP 0.01267 0.41769 8.73786
34 2GCE SFC 0.04714 0.41535 8.73786
35 4V24 GYR 0.04824 0.40249 8.73786
36 4M9Q GNP 0.01472 0.41667 8.81057
37 1KQW RTL 0.002272 0.45295 8.95522
38 4P6X HCY 0.008369 0.42979 9.12698
39 4KBS PX2 0.005827 0.45187 9.28571
40 3KFC 61X 0.04403 0.40415 9.28571
41 5C1M 4VO 0.006495 0.42523 9.45946
42 1ZDT PEF 0.04182 0.40014 9.54357
43 4EES FMN 0.003341 0.45156 9.56522
44 2HPS CTZ 0.01816 0.41213 9.67742
45 1ZGA HMK 0.01135 0.41262 9.70874
46 2A9D MTE 0.01858 0.41227 9.70874
47 1SOX MTE 0.019 0.41179 9.70874
48 4OMJ 2TX 0.03939 0.40671 9.92064
49 1OLM VTQ 0.03605 0.40178 9.92064
50 1Q20 PLO 0.0469 0.40114 10.3679
51 3T50 FMN 0.005725 0.43543 10.6796
52 4YC9 4C1 0.01113 0.41323 10.6796
53 5XDT ZI7 0.03467 0.4018 10.6796
54 1UPT GTP 0.02086 0.40479 10.7143
55 1JAY F42 0.01076 0.41199 10.8491
56 2BYC FMN 0.01495 0.40811 10.9489
57 2IYG FMN 0.00613 0.42704 11.2903
58 4R38 RBF 0.003714 0.45057 11.4286
59 4WAS COO 0.02827 0.41906 11.4286
60 1K7L 544 0.02502 0.41293 11.4286
61 5A8E XTK 0.02005 0.41292 11.4286
62 2NPA MMB 0.0322 0.40446 11.4286
63 1DNP FAD 0.04348 0.40044 11.4286
64 3WCA FPS 0.04056 0.40286 11.6505
65 5LJB RTL 0.001809 0.46272 11.8519
66 3Q9T FAY 0.03224 0.42083 11.9048
67 1QHG ATP 0.0173 0.4078 11.9048
68 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 0.01899 0.42627 12
69 4GU5 FAD 0.01674 0.42466 12.1429
70 2J59 GTP 0.02864 0.40121 12.5
71 1TIQ COA 0.01488 0.40983 12.7778
72 3GDN HBX 0.04284 0.42127 12.8571
73 5AG3 3EB 0.01866 0.4036 12.8571
74 3L9R L9Q 0.03515 0.41437 13.0952
75 4PU5 ANP 0.01771 0.4164 13.5714
76 2RH1 CAU 0.01052 0.42041 13.5922
77 1UOU CMU 0.0158 0.40616 13.5922
78 2ZFZ ARG 0.0492 0.41229 13.9241
79 2WKQ FMN 0.002362 0.45909 14.2857
80 2XTS MTE 0.03187 0.40169 14.5631
81 4GOJ GNP 0.01071 0.42369 15.3439
82 1OW4 2AN 0.004574 0.43084 15.5039
83 3VC3 C6P 0.03252 0.40377 15.873
84 3STD MQ0 0.02144 0.41668 16.9697
85 2R5N RP5 0.04952 0.40287 17.1429
86 2R5N TPP 0.0481 0.40252 17.1429
87 1N9L FMN 0.003218 0.45273 17.4312
88 2V0U FMN 0.002993 0.45333 17.8082
89 1YRX FMN 0.004701 0.43597 18.1818
90 1KQF MGD 0.03422 0.40907 19.4175
91 1OGZ EQU 0.003488 0.43889 20
92 1TW4 CHD 0.006038 0.42818 20
93 2AIB ERG 0.01934 0.41328 20.4082
94 1N6B DMZ 0.01731 0.40909 21.4286
95 1U3D FAD 0.01583 0.42806 24.2718
96 1HG4 LPP 0.02117 0.41549 25.2427
97 2FTB OLA 0.0156 0.43453 28
98 2W83 GTP 0.02368 0.40663 31.5152
99 5DJT FMN 0.002085 0.4623 32.7869
100 4C2V YJA 0.04029 0.40475 36.3636
101 4WN5 MVC 0.02925 0.40138 36.5217
102 1RM6 FAD 0.01045 0.44555 37.8641
103 1YP0 PEF 0.0135 0.4219 50
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