Receptor
PDB id Resolution Class Description Source Keywords
1ZOY 2.4 Å EC: 1.3.5.1 CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY COMPLEX II FR HEART AT 2.4 ANGSTROMS SUS SCROFA SUCCINATE UBIQUINONE OXIDOREDUCTASE MITOCHONDRIAL RESPIRATCOMPLEX II MEMBRANE PROTEIN STRUCTURE OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY MEMB PROTEIN COMPLEX II CELL(CAMBRIDGE,MASS.) V. 121 1043 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EPH D:1306;
D:1307;
 Invalid;
Invalid;
 none;
none;
 submit data
709.933 C39 H68 N O8 P CCCC=...
F3S B:304;
 Part of Protein;
 none;
 submit data
295.795 Fe3 S4 S1[Fe...
FAD A:700;
 Part of Protein;
 none;
 submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
FES B:302;
 Part of Protein;
 none;
 submit data
175.82 Fe2 S2 S1[Fe...
HEM C:1305;
 Part of Protein;
 none;
 submit data
616.487 C34 H32 Fe N4 O4 Cc1c2...
SF4 B:303;
 Part of Protein;
 none;
 submit data
351.64 Fe4 S4 [S]12...
UQ1 B:1201;
 Valid;
 none;
 submit data
250.29 C14 H18 O4 CC1=C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZOY 2.4 Å EC: 1.3.5.1 CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY COMPLEX II FR HEART AT 2.4 ANGSTROMS SUS SCROFA SUCCINATE UBIQUINONE OXIDOREDUCTASE MITOCHONDRIAL RESPIRATCOMPLEX II MEMBRANE PROTEIN STRUCTURE OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY MEMB PROTEIN COMPLEX II CELL(CAMBRIDGE,MASS.) V. 121 1043 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
5 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
5 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: UQ1; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 UQ1 1 1
2 UQ2 0.653061 0.84375
3 UQ9 0.603774 0.794118
4 U10 0.603774 0.794118
5 UQ5 0.603774 0.818182
6 UQ 0.603774 0.794118
7 UQ7 0.603774 0.794118
8 UQ8 0.603774 0.794118
9 DCQ 0.4 0.742857
Similar Ligands (3D)
Ligand no: 1; Ligand: UQ1; Similar ligands found: 194
No: Ligand Similarity coefficient
1 F5C 0.9279
2 6HP 0.9207
3 X04 0.9192
4 Z25 0.9080
5 CR1 0.9070
6 IBM 0.9066
7 X0T 0.9064
8 G6P 0.9037
9 3TV 0.9034
10 1Q4 0.9030
11 AC2 0.8996
12 B61 0.8977
13 NWL 0.8974
14 5V7 0.8962
15 E7R 0.8955
16 STZ 0.8946
17 YX1 0.8946
18 RH1 0.8944
19 H2B 0.8943
20 HBI 0.8943
21 BG6 0.8941
22 8Y7 0.8940
23 CPW 0.8939
24 PMP 0.8935
25 CGW 0.8934
26 5WS 0.8929
27 PLP 0.8929
28 1QV 0.8922
29 NYJ 0.8921
30 GZV 0.8916
31 4AB 0.8914
32 L1Q 0.8913
33 BGN 0.8907
34 QIF 0.8907
35 0J5 0.8903
36 NAG 0.8901
37 GI2 0.8901
38 B0K 0.8900
39 4R1 0.8898
40 PVQ 0.8888
41 4B0 0.8883
42 PXP 0.8882
43 PVK 0.8881
44 9GP 0.8880
45 LP8 0.8879
46 LIP 0.8879
47 AZC 0.8876
48 I4D 0.8872
49 K68 0.8872
50 K3Q 0.8871
51 L3L 0.8868
52 2AN 0.8862
53 5WT 0.8860
54 64F 0.8857
55 NBG 0.8854
56 M3F 0.8854
57 MAG 0.8849
58 OX2 0.8848
59 8RK 0.8847
60 JY2 0.8844
61 CG 0.8844
62 M1D 0.8835
63 3GX 0.8830
64 4KR 0.8825
65 NTF 0.8825
66 MQG 0.8822
67 B2E 0.8822
68 3UG 0.8812
69 BDI 0.8812
70 FER 0.8812
71 PMM 0.8811
72 PLR 0.8811
73 64E 0.8810
74 4GP 0.8807
75 6TJ 0.8807
76 RUG 0.8805
77 3JM 0.8804
78 FSU 0.8804
79 GA2 0.8803
80 GI1 0.8801
81 QNM 0.8797
82 L21 0.8797
83 52F 0.8796
84 UXH 0.8796
85 SXX 0.8787
86 GJK 0.8786
87 6GP 0.8785
88 JXK 0.8783
89 5NN 0.8780
90 NWD 0.8773
91 NPL 0.8772
92 Q5M 0.8771
93 NEO 0.8770
94 PE2 0.8768
95 22T 0.8759
96 MUR 0.8759
97 4WF 0.8757
98 BA5 0.8754
99 OA4 0.8750
100 3WJ 0.8750
101 NBV 0.8749
102 3LJ 0.8749
103 V13 0.8748
104 MFZ 0.8746
105 UAY 0.8743
106 CG8 0.8741
107 IPD 0.8741
108 9KZ 0.8736
109 GLP 0.8736
110 QUB 0.8732
111 NQH 0.8731
112 3JL 0.8730
113 LOG 0.8723
114 ALR 0.8722
115 ONZ 0.8720
116 68A 0.8720
117 H4B 0.8718
118 92O 0.8714
119 4QY 0.8707
120 4FE 0.8704
121 T6Z 0.8698
122 S0G 0.8695
123 6DQ 0.8693
124 9F8 0.8691
125 ZSP 0.8687
126 DT7 0.8686
127 774 0.8685
128 GDL 0.8683
129 3JN 0.8683
130 GC2 0.8682
131 PNX 0.8677
132 BIO 0.8676
133 3AK 0.8674
134 SNY 0.8673
135 O9Z 0.8672
136 ADL 0.8671
137 O9Q 0.8669
138 1BW 0.8667
139 HBO 0.8664
140 CHQ 0.8662
141 OAL 0.8661
142 GI4 0.8660
143 G1P 0.8660
144 ML1 0.8658
145 JXT 0.8657
146 JOH 0.8653
147 CX4 0.8652
148 3WL 0.8651
149 FNT 0.8650
150 TLG 0.8648
151 VPU 0.8648
152 9OF 0.8648
153 ZEA 0.8640
154 AQN 0.8640
155 2LT 0.8638
156 JYT 0.8637
157 TQ3 0.8635
158 RZH 0.8631
159 2GQ 0.8625
160 ASE 0.8623
161 7GP 0.8618
162 KF5 0.8615
163 NCV 0.8611
164 ZHA 0.8611
165 S7P 0.8607
166 UN9 0.8605
167 SDN 0.8604
168 5XL 0.8602
169 GRX 0.8602
170 SGW 0.8602
171 3Y7 0.8601
172 BGP 0.8600
173 QUE 0.8596
174 KLK 0.8592
175 PZP 0.8582
176 XFE 0.8579
177 2K8 0.8578
178 1V3 0.8577
179 1V4 0.8577
180 96Z 0.8575
181 W8L 0.8575
182 AXX 0.8575
183 BHS 0.8569
184 BJ4 0.8569
185 B5A 0.8569
186 YEX 0.8563
187 RVE 0.8561
188 MFR 0.8560
189 MXD 0.8557
190 96R 0.8554
191 KY3 0.8553
192 57D 0.8535
193 DBQ 0.8534
194 RGG 0.8528
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZOY; Ligand: UQ1; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1zoy.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
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