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Receptor
PDB id Resolution Class Description Source Keywords
1ZOY 2.4 Å EC: 1.3.5.1 CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY COMPLEX II FROM PORCINE HEART AT 2.4 ANGSTROMS SUS SCROFA SUCCINATE UBIQUINONE OXIDOREDUCTASE MITOCHONDRIAL RESPIRATORY COMPLEX II MEMBRANE PROTEIN STRUCTURE
Ref.: CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY MEMBRANE PROTEIN COMPLEX II CELL(CAMBRIDGE,MASS.) V. 121 1043 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EPH D:1306;
D:1307;
Invalid;
Invalid;
none;
none;
submit data
709.933 C39 H68 N O8 P CCCC=...
F3S B:304;
Part of Protein;
none;
submit data
295.795 Fe3 S4 S1[Fe...
FAD A:700;
Part of Protein;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
FES B:302;
Part of Protein;
none;
submit data
175.82 Fe2 S2 S1[Fe...
HEM C:1305;
Part of Protein;
none;
submit data
616.487 C34 H32 Fe N4 O4 Cc1c2...
SF4 B:303;
Part of Protein;
none;
submit data
351.64 Fe4 S4 [S]12...
UQ1 B:1201;
Valid;
none;
submit data
250.29 C14 H18 O4 CC1=C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZOY 2.4 Å EC: 1.3.5.1 CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY COMPLEX II FROM PORCINE HEART AT 2.4 ANGSTROMS SUS SCROFA SUCCINATE UBIQUINONE OXIDOREDUCTASE MITOCHONDRIAL RESPIRATORY COMPLEX II MEMBRANE PROTEIN STRUCTURE
Ref.: CRYSTAL STRUCTURE OF MITOCHONDRIAL RESPIRATORY MEMBRANE PROTEIN COMPLEX II CELL(CAMBRIDGE,MASS.) V. 121 1043 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
5 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
5 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: UQ1; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 UQ1 1 1
2 UQ2 0.653061 0.84375
3 UQ8 0.603774 0.794118
4 UQ9 0.603774 0.794118
5 UQ5 0.603774 0.818182
6 UQ7 0.603774 0.794118
7 U10 0.603774 0.794118
8 UQ 0.603774 0.794118
9 DCQ 0.4 0.742857
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZOY; Ligand: UQ1; Similar sites found with APoc: 156
This union binding pocket(no: 1) in the query (biounit: 1zoy.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 1ZDU P3A 2.04082
2 3O01 DXC 2.27273
3 3OV6 MK0 2.91262
4 3IS2 FAD 3.8961
5 4HIA FMN 3.97727
6 3D72 FAD 4.02685
7 2YFB SIN 4.65116
8 5ZM0 FAD 4.85437
9 4QJR PIZ 4.89796
10 1LEK GLU GLN TYR LYS PHE TYR SER VAL 5.05051
11 3EM0 CHD 5.07246
12 5A86 D7E 5.15873
13 2HZL PYR 5.20548
14 2Z6D FMN 5.38462
15 3V1V GST 5.54273
16 5MBC FMN 5.55556
17 2QO4 CHD 5.55556
18 1M5B BN1 5.82524
19 4U63 FAD 5.82524
20 6M8N MLI 5.95238
21 5U98 1KX 6.06061
22 5U98 VAL THR THR ASP ILE GLN VAL LYS VAL 6.06061
23 5T70 THR SER ASN LEU GLN GLU GLN ILE GLY TRP 6.06061
24 3S43 478 6.06061
25 2FH5 GTP 6.07477
26 2Z6C FMN 6.20155
27 4GCZ FMN 6.42857
28 5UGW GSH 6.42857
29 1NP7 FAD 6.79612
30 5B0W 22B 6.79612
31 2OZ5 7XY 6.79612
32 2BII MTV 6.79612
33 4QGE 35O 6.79612
34 3P7N FMN 7.14286
35 5JZI LYS LEU VAL ALA LEU GLY ILE ASN ALA VAL 7.14286
36 3QDJ ALA ALA GLY ILE GLY ILE LEU THR VAL 7.14286
37 5HCY 60D 7.14286
38 1N8V BDD 7.14286
39 2V1O COA 7.28477
40 4OIV XX9 7.52212
41 6AYI C3G 7.53769
42 3G4G D71 7.53968
43 3KCC CMP 7.76699
44 4O4K 2PK 7.76699
45 3KO0 TFP 7.92079
46 4C01 QY9 7.93651
47 4OHU 2TK 7.95848
48 4OHU NAD 7.95848
49 4QYN RTL 8.27068
50 2PR5 FMN 8.33333
51 4WO4 JLS 8.33333
52 4E2J MOF 8.4
53 3GN8 DEX 8.43373
54 5XC5 GTP 8.52273
55 1ONI BEZ 8.73786
56 2GCE SFC 8.73786
57 1KSH GDP 8.73786
58 4Q0A 4OA 8.73786
59 4V24 GYR 8.73786
60 4M9Q GNP 8.81057
61 1KQW RTL 8.95522
62 4P6X HCY 9.12698
63 3GFZ FMN 9.12698
64 4KBS PX2 9.28571
65 1TKB N1T 9.28571
66 3KFC 61X 9.28571
67 5C1M 4VO 9.45946
68 1ZDT PEF 9.54357
69 4EES FMN 9.56522
70 2HPS CTZ 9.67742
71 1ZGA HMK 9.70874
72 2A9D MTE 9.70874
73 1SOX MTE 9.70874
74 5DI3 GNP 9.70874
75 4OMJ 2TX 9.92064
76 1OLM VTQ 9.92064
77 1XNG DND 10
78 5DQ8 FLF 10
79 4S15 4D8 10.1562
80 3TKY SAH 10.3175
81 1Q20 PLO 10.3679
82 1Q20 A3P 10.3679
83 1X0P FAD 10.4895
84 6GG9 FMN 10.4938
85 3T50 FMN 10.6796
86 4YC9 4C1 10.6796
87 5XDT ZI7 10.6796
88 3KU0 ADE 10.6796
89 5K53 STE 10.7143
90 1UPT GTP 10.7143
91 1JAY F42 10.8491
92 1XZ3 ICF 10.9195
93 2BYC FMN 10.9489
94 2IYG FMN 11.2903
95 4R38 RBF 11.4286
96 4WAS COO 11.4286
97 1K7L 544 11.4286
98 5A8E XTK 11.4286
99 2NPA MMB 11.4286
100 1DNP FAD 11.4286
101 6GBV FMN 11.6438
102 3WCA FPS 11.6505
103 5LJB RTL 11.8519
104 1QHG ATP 11.9048
105 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 12
106 4GU5 FAD 12.1429
107 2J59 GTP 12.5
108 6F8B CXH 12.6246
109 1TIQ COA 12.7778
110 3GDN HBX 12.8571
111 5AG3 3EB 12.8571
112 5TK8 7D5 12.8866
113 3L9R L9Q 13.0952
114 4PU5 ANP 13.5714
115 2RH1 CAU 13.5922
116 1UOU CMU 13.5922
117 5SVV FMN 13.8686
118 2ZFZ ARG 13.9241
119 2WKQ FMN 14.2857
120 4QOM PYG 14.5631
121 2XTS MTE 14.5631
122 4ZI2 GNP 15.2632
123 4GOJ GNP 15.3439
124 1OW4 2AN 15.5039
125 3VC3 C6P 15.873
126 5ISZ GLY ILE LEU GLY PHE VAL PHE THR LEU 16.5
127 3STD MQ0 16.9697
128 4WUJ FMN 17.0068
129 2R5N RP5 17.1429
130 2R5N TPP 17.1429
131 1N9L FMN 17.4312
132 5FI3 NAP 17.4757
133 2V0U FMN 17.8082
134 1YRX FMN 18.1818
135 2P3B 3TL 19.1919
136 1KQF MGD 19.4175
137 1OGZ EQU 20
138 1TW4 CHD 20
139 2AIB ERG 20.4082
140 1N6B DMZ 21.4286
141 1U3D FAD 24.2718
142 1HG4 LPP 25.2427
143 4ZA8 F5C 25.7143
144 4ZA8 4LU 25.7143
145 4ZA8 FZZ 25.7143
146 5EFW FMN 26.2069
147 5DKK FMN 27.1845
148 2FTB OLA 28
149 5LWY OLB 28.5714
150 2W83 GTP 31.5152
151 5DJT FMN 32.7869
152 4WZH FMN 35
153 5DJU FMN 36.0656
154 4C2V YJA 36.3636
155 4WN5 MVC 36.5217
156 1RM6 FAD 37.8641
157 1YP0 PEF 50
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