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Receptor
PDB id Resolution Class Description Source Keywords
1ZC3 2 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE RAL-BINDING DOMAIN OF EXO84 IN COMPLEX WITH THE ACTIVE RALA HOMO SAPIENS EXOCYTOSIS SMALL GTPASE GTP-BINDING PROTEIN SIGNALING PROTEIN
Ref.: EXO84 AND SEC5 ARE COMPETITIVE REGULATORY SEC6/8 EFFECTORS TO THE RALA GTPASE. EMBO J. V. 24 2064 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GNP A:700;
C:800;
Valid;
Valid;
none;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
MG A:500;
C:600;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZC3 2 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE RAL-BINDING DOMAIN OF EXO84 IN COMPLEX WITH THE ACTIVE RALA HOMO SAPIENS EXOCYTOSIS SMALL GTPASE GTP-BINDING PROTEIN SIGNALING PROTEIN
Ref.: EXO84 AND SEC5 ARE COMPETITIVE REGULATORY SEC6/8 EFFECTORS TO THE RALA GTPASE. EMBO J. V. 24 2064 2005
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 1ZC4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 1ZC3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1ZC4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 1ZC3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50% Homology Family (47)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 3QBT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 5WFO - 5UU C19 H16 Cl F N2 c1cc(ccc1N....
3 6FA3 Kd = 0.038 uM D1Z C30 H36 N4 O5 CN(C)Cc1cc....
4 5WFQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 5O2T Kd = 3.9 nM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
6 5WPM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 5WFR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 5UFQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 6AMB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 6FA1 - D2Z C20 H25 N2 O4 C[NH+](C)C....
11 5UFE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 5WFP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 5WHB - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 5WPL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
15 5XCO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 1NVU - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
17 5WHE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
18 3KUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
19 1C1Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
20 5TAR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
21 4DXA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
22 4HDO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
23 3MJH - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
24 5E95 Kd = 15.7 nM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
25 3CF6 - SP1 C10 H12 N5 O5 P S c1nc(c2c(n....
26 2CJW Kd = 2.5 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
27 6FA4 Kd = 0.051 uM D1W C23 H25 N3 O3 CN(C)Cc1cc....
28 2C5L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
29 4K81 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
30 1LFD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
31 4KVG - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
32 3TNF - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
33 1ZC4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
34 1ZC3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
35 2A9K - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
36 2A78 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
37 1WQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
38 3TKL - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
39 3DDC - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
40 3KUD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
41 1TU3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
42 1UAD Ka = 7260000 M^-1 GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
43 5O74 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
44 3SFV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
45 4URZ Kd = 3 mM VJP C11 H14 N2 O3 S c1cc(ccc1N....
46 4URX Kd = 1.3 mM HXY C11 H14 Br N c1cc(ccc1C....
47 4URY Kd = 6 mM RV1 C10 H12 N2 O3 S c1cc(ccc1N....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GNP; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 9GM 1 1
3 GDP 0.839506 0.973684
4 GP3 0.82716 0.948718
5 GTP 0.809524 0.973684
6 GNH 0.807229 0.986842
7 G1R 0.77907 0.961039
8 GCP 0.77907 0.948718
9 GSP 0.770115 0.925
10 5GP 0.756098 0.960526
11 G 0.756098 0.960526
12 G2R 0.747253 0.936709
13 GMV 0.747126 0.948718
14 GAV 0.714286 0.936709
15 GP2 0.712644 0.936709
16 G2P 0.711111 0.936709
17 Y9Z 0.708333 0.880952
18 GDC 0.690722 0.936709
19 GDD 0.690722 0.936709
20 GKE 0.690722 0.936709
21 G5P 0.686869 0.948718
22 GPG 0.684211 0.936709
23 GTG 0.683673 0.91358
24 GDR 0.683673 0.936709
25 GFB 0.683673 0.936709
26 JB2 0.68 0.936709
27 GKD 0.68 0.936709
28 6CK 0.676768 0.91358
29 G3A 0.676768 0.948718
30 GDX 0.673267 0.948718
31 ALF 5GP 0.67033 0.86747
32 YGP 0.663265 0.879518
33 GPD 0.656863 0.902439
34 ALF GDP 0.645833 0.86747
35 GDP AF3 0.645833 0.86747
36 GDP ALF 0.645833 0.86747
37 JB3 0.641509 0.925
38 DBG 0.640351 0.974359
39 G3D 0.638298 0.960526
40 G4P 0.625 0.960526
41 GMP 0.621951 0.857143
42 NGD 0.62037 0.936709
43 GGM 0.618182 0.925926
44 0O2 0.616162 0.960526
45 2MD 0.603604 0.870588
46 CAG 0.60177 0.904762
47 U2G 0.590909 0.91358
48 FEG 0.590909 0.858824
49 GDP 7MG 0.590476 0.888889
50 MGD 0.587719 0.870588
51 G G 0.586538 0.924051
52 ZGP 0.585586 0.848837
53 CG2 0.580357 0.91358
54 ANP 0.568421 0.922078
55 PGD 0.567797 0.902439
56 MD1 0.567797 0.870588
57 3GP 0.56044 0.922078
58 TPG 0.558333 0.822222
59 GH3 0.55 0.948052
60 FE9 0.546219 0.778947
61 GPX 0.539216 0.922078
62 G4M 0.539062 0.860465
63 DGI 0.536082 0.9
64 BGO 0.535088 0.901235
65 IDP 0.53125 0.947368
66 DGT 0.53 0.9
67 2GP 0.526882 0.935065
68 G1R G1R 0.520325 0.901235
69 GCP G 0.518868 0.897436
70 A G 0.516949 0.911392
71 U A G G 0.512605 0.911392
72 G A A A 0.504202 0.9
73 AGO 0.504202 0.91358
74 P2G 0.5 0.860759
75 G1G 0.5 0.902439
76 R7I 0.49505 0.922078
77 MGP 0.49505 0.936709
78 R5I 0.49505 0.922078
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 AKW 0.483051 0.869048
83 DG 0.474227 0.8875
84 DGP 0.474227 0.8875
85 G U 0.466667 0.878049
86 IMP 0.463918 0.934211
87 G2Q 0.462963 0.936709
88 GPC 0.459677 0.858824
89 G C 0.459016 0.878049
90 GTA 0.448276 0.91358
91 G7M 0.444444 0.924051
92 MAP 0.439252 0.898734
93 G G G RPC 0.435484 0.853659
94 B4P 0.434343 0.871795
95 AP5 0.434343 0.871795
96 ADP 0.434343 0.896104
97 A2D 0.43299 0.871795
98 AT4 0.43 0.8625
99 G G G C 0.426357 0.890244
100 AU1 0.425743 0.922078
101 SGP 0.425743 0.807229
102 BA3 0.424242 0.871795
103 A G C C 0.423077 0.888889
104 35G 0.423077 0.909091
105 PCG 0.423077 0.909091
106 C2E 0.423077 0.897436
107 APC G U 0.421875 0.864198
108 HEJ 0.421569 0.896104
109 ATP 0.421569 0.896104
110 ACQ 0.419048 0.873418
111 5GP 5GP 0.419048 0.860759
112 5FA 0.417476 0.896104
113 AQP 0.417476 0.896104
114 01G 0.417391 0.880952
115 AN2 0.415842 0.909091
116 UNP 0.415842 0.810127
117 6AD 0.415094 0.821429
118 M33 0.411765 0.860759
119 ITT 0.411765 0.846154
120 G C C C 0.410448 0.901235
121 HFD 0.409524 0.851852
122 G U34 0.408 0.86747
123 ACP 0.407767 0.873418
124 6YZ 0.407407 0.873418
125 AR6 0.403846 0.871795
126 APR 0.403846 0.871795
127 DG DG 0.403509 0.845238
128 A4P 0.403226 0.848837
129 UCG 0.402985 0.888889
130 SAP 0.4 0.851852
131 AGS 0.4 0.851852
132 AD9 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZC3; Ligand: GNP; Similar sites found with APoc: 587
This union binding pocket(no: 1) in the query (biounit: 1zc3.bio1) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 1UPT GTP None
2 5XKT GNP None
3 4PYA 2X3 None
4 3BFV ADP None
5 2IL4 COA None
6 2H5Z CTO 1.63934
7 4WOP CTP 1.71429
8 1P9B GDP 1.76991
9 1P9B HDA 1.76991
10 4GOX A3P 2.28571
11 1XP8 AGS 2.65487
12 1GOJ ADP 2.85714
13 1DAK ADP 2.85714
14 1DAK DPU 2.85714
15 2HXW FLC 2.85714
16 1WY7 SAH 2.85714
17 1CR1 TTP 2.85714
18 2XT3 ADP 3.42857
19 4U00 ADP 3.42857
20 4CVN ADP 3.42857
21 2ZFI ADP 3.42857
22 1L2T ATP 3.42857
23 3BER AMP 3.42857
24 4C2C ALA ALA ALA 3.42857
25 4X1Z FUC GAL NDG 3.42857
26 4C2G ALA ALA ALA ALA 3.42857
27 1LVG ADP 3.53982
28 5VGR GDP 3.53982
29 4RD0 GDP 4
30 2PZE ATP 4
31 4WZ6 ATP 4
32 1XX6 ADP 4
33 5G41 AP5 4
34 1Z83 AP5 4
35 2Y65 ADP 4.42478
36 1M7G AV2 4.42478
37 4JLV ADP 4.42478
38 2OFW ADX 4.42478
39 4ZDJ UTP 4.42478
40 1M7G ADX 4.42478
41 2PEZ GGZ 4.42478
42 2PEZ DAT 4.42478
43 1M7G ADP 4.42478
44 5J6Y GLC 4.42478
45 5J6Y BGC 4.42478
46 3R7F CP 4.42478
47 1AQU A3P 4.42478
48 2JK0 ASP 4.42478
49 1BO4 COA 4.42478
50 2O66 FLC 4.44444
51 1KK1 GNP 4.57143
52 3A1S GDP 4.57143
53 2OBM ADP 4.57143
54 5IFS ADP 4.57143
55 1D2N ANP 4.57143
56 2Q37 3AL 4.57143
57 3IUY AMP 4.57143
58 3HU3 AGS 4.57143
59 5VYQ FON 4.57143
60 1JI0 ATP 5.14286
61 3FB4 AP5 5.14286
62 5I34 GDP 5.14286
63 2TOH HBI 5.14286
64 3H86 AP5 5.14286
65 1DKU AP2 5.14286
66 2VVG ADP 5.30973
67 5WC2 ADP 5.30973
68 3P4X ADP 5.30973
69 3ZS9 ADP ALF 5.30973
70 2WOJ ADP ALF 5.30973
71 1IN4 ADP 5.30973
72 4R2I ANP 5.30973
73 1VHT BA3 5.30973
74 1QHG ATP 5.30973
75 3NJQ NJQ 5.30973
76 1PZM 5GP 5.30973
77 2QZ4 ADP 5.30973
78 5H4S RAM 5.30973
79 5X40 ACP 5.30973
80 3KC1 2T6 5.30973
81 5J1J ANP 5.61404
82 5H7K GDP 5.71429
83 3PQC GDP 5.71429
84 5H7J GCP 5.71429
85 2OZE AGS 5.71429
86 3BP1 GUN 5.71429
87 2BIF ANP 5.71429
88 2BIF SIN 5.71429
89 1G41 ADP 5.71429
90 1UJ2 C5P 5.71429
91 2BVE PH5 5.88235
92 2ZTS ADP 5.9761
93 2KIN ADP 6.19469
94 3ZFD ANP 6.19469
95 1T5C ADP 6.19469
96 4KFU ACP 6.19469
97 1OXV ANP 6.19469
98 2B8W ALF 5GP 6.19469
99 5BQ5 ADP BEF 6.19469
100 2CE7 ADP 6.19469
101 1NY5 ADP 6.19469
102 1ZGS XMM 6.19469
103 1DQN IMU 6.19469
104 5MEX PAP 6.19469
105 1V6A TRE 6.19469
106 4NE2 SH2 6.19469
107 4NE2 ADP 6.19469
108 1QF9 ALF 6.19469
109 1QF9 ADP 6.19469
110 1QF9 C5P 6.19469
111 1XXR MAN 6.21118
112 3CNL GNP 6.28571
113 3KTA AP5 6.28571
114 3VX3 ADP 6.28571
115 4FUA PGH 6.28571
116 4QM7 GTP 6.43275
117 2QN6 GDP 6.45161
118 4NON GDP 6.85714
119 4E03 ADP 6.85714
120 1SVI GDP 6.85714
121 2IS6 ADP 6.85714
122 4P4T GDP 6.85714
123 4C25 13P 6.85714
124 5AHO TLA 6.85714
125 5G3Y ADP 6.85714
126 4B1M FRU FRU 6.85714
127 4OI4 ATP 6.85714
128 2WJG GDP 7.07965
129 4FRZ ADP 7.07965
130 6A20 ADP 7.07965
131 4V03 ADP 7.07965
132 3EZ2 ADP 7.07965
133 3FKQ ATP 7.07965
134 4R43 GDP 7.07965
135 5K5Z ANP 7.07965
136 4TTQ ATP 7.07965
137 4YJ1 ADP 7.07965
138 2J5V PCA 7.07965
139 4YS0 ADP 7.07965
140 4RZ3 ADP 7.07965
141 2BEK ATP 7.07965
142 3VM7 GLC 7.07965
143 4OHY ANP 7.07965
144 1SVM ATP 7.07965
145 2ATJ BHO 7.07965
146 3DC4 ADP 7.07965
147 1TL2 NDG 7.07965
148 2J5V RGP 7.07965
149 5O96 SAM 7.07965
150 1R6B ADP 7.07965
151 1NHX PEP 7.07965
152 1ZUI SKM 7.14286
153 2WJH FLC 7.22892
154 2WJH GDP 7.22892
155 1TAD ALF 7.42857
156 1TAD GDP 7.42857
157 5HCN GCP 7.42857
158 4D81 ADP 7.42857
159 4KVA GTP 7.42857
160 4FCW ADP 7.42857
161 5HR5 ADP 7.42857
162 2X7I CIT 7.42857
163 3AB4 THR 7.42857
164 1LOB MMA 7.42857
165 5W7Q GDP 7.9646
166 5KSZ GCP 7.9646
167 4LYA ATP 7.9646
168 1D2E GDP 7.9646
169 4MKG AP5 7.9646
170 5ODQ 9SB 7.9646
171 3QOX SAH 7.9646
172 1KO8 6PG 7.9646
173 1NST A3P 7.9646
174 4CTA ATP 7.9646
175 5ZI9 FLC 7.9646
176 2NCD ADP 7.9646
177 5U32 GDP 8
178 4ZNL BEF ADP 8
179 4LJ9 ACP 8
180 2XAU ADP 8
181 4PJ3 ANP 8
182 3S6X SIA GAL BGC 8
183 1WAP TRP 8
184 3RK0 AMP 8
185 2AWN ADP 8.57143
186 5I0H ADP BEF 8.57143
187 3T1O GDP 8.57143
188 1XMV ADP 8.57143
189 5XDR ADP 8.57143
190 3RLF ANP 8.57143
191 1E2K TMC 8.57143
192 3FVQ ATP 8.57143
193 3WY9 GDP 8.84956
194 5KSP GDP 8.84956
195 5IRR GSP 8.84956
196 1WDT GTP 8.84956
197 3WYA GDP 8.84956
198 1TQ4 GDP 8.84956
199 4B47 GDP 8.84956
200 2FAH GDP 8.84956
201 1IWE IMP 8.84956
202 6C90 ADP 8.84956
203 1YXM ADE 8.84956
204 2FSH ANP 8.84956
205 4Q1A 2XZ 8.84956
206 4Q1A UDP 8.84956
207 1ZIN AP5 8.84956
208 1FNZ A2G 8.84956
209 2GWH A3P 8.84956
210 4IOK ADP 8.84956
211 4IOK XPO 8.84956
212 4PVR ASP 8.84956
213 5W75 GDP 9.14286
214 5TSH ADP 9.14286
215 5TSH ANP 9.14286
216 1XKV ATP 9.14286
217 4NU0 AP5 9.14286
218 4QRH 0O2 9.14286
219 1OFH ADP 9.1954
220 5TQZ GLC 9.33333
221 5W76 GDP 9.71429
222 3NHB ADP 9.71429
223 1G6O ADP 9.71429
224 3QKT ANP 9.71429
225 1YTM ATP 9.71429
226 3SJK LYS PRO VAL LEU ARG THR ALA 9.71429
227 3QXC ATP 9.71429
228 4M9Q GNP 9.73451
229 1BG2 ADP 9.73451
230 2RCN GDP 9.73451
231 5ZXD ATP 9.73451
232 4ZG4 VO4 ADP 9.73451
233 5AK0 8V1 9.73451
234 6FMC DUE 9.73451
235 2QEN ADP 9.73451
236 1S3G AP5 9.73451
237 3UIE ANP 9.73451
238 4Z7X 3CX 9.73451
239 2JLR ANP 9.73451
240 2WW4 ADP 9.73451
241 1OBV FMN 9.73451
242 1GXU 2HP 9.89011
243 2GKS ADP 10.2857
244 5GVR LMR 10.2857
245 1OS1 PYR 10.2857
246 1U3G ADP 10.2857
247 1OS1 ATP 10.2857
248 6H5E ANP 10.2857
249 1QHH ATP 10.4348
250 2C77 GNP 10.6195
251 1SVK ALF GDP 10.6195
252 2C78 GNP 10.6195
253 2IYL GDP 10.6195
254 2WHX ADP 10.6195
255 4YMU ATP 10.6195
256 4WZA ACP 10.6195
257 2OM2 GDP 10.6195
258 4WZA ADP 10.6195
259 3T34 GDP 10.6195
260 1U0J ADP 10.6195
261 3QF7 ANP 10.6195
262 4Y4V DAL 10.6195
263 5FJJ MAN 10.6195
264 4MKF AP5 10.6195
265 5IRN ADP 10.6195
266 4PU6 ASP 10.6195
267 4BAS GNP 10.8571
268 6DEF GCP 10.8571
269 5GOE GDP 10.8571
270 1R0X ATP 10.8571
271 5M7P ADP 10.8571
272 2Q2Y ADP 10.8571
273 2Q2Y MKR 10.8571
274 3BFX A3P 10.8571
275 1RZU ADP 10.8571
276 1F2U ATP 11.4094
277 3U6B GDP 11.4286
278 4P3Y GDP 11.4286
279 1D8T GDP 11.4286
280 2BVN GNP 11.4286
281 3U6K GDP 11.4286
282 4PC3 GDP 11.4286
283 5JBQ GDP 11.4286
284 4G5G GDP 11.4286
285 2FNA ADP 11.4286
286 4U60 SIA GAL NGA 11.4286
287 4U60 SIA 11.4286
288 2W58 ADP 11.5044
289 1V8K ANP 11.5044
290 3FWY ADP 11.5044
291 3B5J 12D 11.5044
292 3BOS CDP 11.5044
293 2GK6 ADP 11.5044
294 1APZ ASP 11.5044
295 5H68 AGS 11.5044
296 2CBZ ATP 12
297 5YV5 ADP 12
298 1YQT ADP 12
299 2HF9 GSP 12
300 2D2F ADP 12
301 2C9O ADP 12
302 6ACS CIT 12
303 3IO3 ADP 12.3563
304 3H4S ADP 12.3894
305 4IHQ ADP 12.3894
306 4QOS ADP 12.3894
307 1Y63 ADP 12.3894
308 4HSE ADP 12.3894
309 5A7Y SAH 12.3894
310 5KXE 6Y2 12.3894
311 1QAN SAH 12.3894
312 5NM7 GLY 12.3894
313 1DCP HBI 12.5
314 1W0J ADP 12.5714
315 4XVU ATP 12.5714
316 4XTR ATP 12.5714
317 1W0J ADP BEF 12.5714
318 6GSG RCO 12.5714
319 4XTR ADP 12.5714
320 4TL6 ANP 12.5714
321 1F9V ADP 12.5714
322 4PPF FLC 13.1429
323 4H1V GNP 13.1429
324 5ZBR ANP 13.1429
325 2VB6 ADP BEF 13.1429
326 1QF5 GDP 13.1429
327 1QF5 RPL 13.1429
328 4PFO ADP 13.1429
329 5H67 ATP 13.1429
330 5J1S ATP 13.1429
331 1W7J ADP BEF 13.245
332 3KJI ADP 13.2743
333 2CDN ADP 13.2743
334 1IHU AF3 13.2743
335 3ZQ6 ADP ALF 13.2743
336 1IHU ADP 13.2743
337 1W5T ANP 13.2743
338 1W5T ADP 13.2743
339 5N69 ADP 13.2743
340 6AIC AMP 13.2743
341 4Z2S NDG 13.3803
342 4Z2S NAG 13.3803
343 1FQJ ALF 13.6054
344 1FQK ALF 13.6054
345 1FQJ GDP 13.6054
346 1FQK GDP 13.6054
347 4J0Q GDP 13.7143
348 5UIV ADP 13.7143
349 1G8S MET 13.7143
350 5ZB0 TYD 13.7143
351 5ZB0 ADP 13.7143
352 1NN5 2DT 13.7143
353 1NN5 ANP 13.7143
354 2GUC MAN 13.9344
355 2NU5 NAG 13.9344
356 2GUD BMA 13.9344
357 2GUD MAN 13.9344
358 2HYQ MAN MAN 13.9344
359 2HYR BGC GLC 13.9344
360 2CK3 ANP 14
361 2CK3 ADP 14
362 1B0U ATP 14.1593
363 4PX9 ADP 14.1593
364 1Z6T ADP 14.1593
365 3B7G ANP 14.1593
366 2D7I NGA 14.1593
367 2F5X ASP 14.1593
368 5MVR ADP 14.1975
369 2ODE ALF GDP 14.2857
370 4HI0 GDP 14.2857
371 5LB3 ADP 14.2857
372 2IXE ATP 14.2857
373 4JLS 3ZE 14.4737
374 1G7S GDP 14.8571
375 2DPY ADP 14.8571
376 5LTJ ADP 14.8571
377 1G7C 5GP 14.8936
378 2D7D ADP 15
379 3LRE ADP 15.0442
380 4AG5 ADP 15.0442
381 1FP6 ADP 15.0442
382 1U2Z SAH 15.0442
383 1GOT GDP 15.0685
384 3CM2 X23 15.3846
385 4DCT GDP 15.4286
386 4LPS GDP 15.4286
387 1JJ7 ADP 15.4286
388 4LO6 SIA GAL 15.4286
389 6G14 G4P 15.9292
390 2HCJ GDP 15.9292
391 3ITJ CIT 15.9292
392 5VHC BEF ADP 15.9292
393 4BQS K2Q 15.9292
394 4BQS ADP 15.9292
395 3W5J GDP 16
396 4YDS ATP 16
397 4NCN GTP 16.5714
398 4TMZ GSP 16.5714
399 1DAR GDP 16.5714
400 2CHG ANP 16.5714
401 3RC3 ANP 16.5714
402 2V7Q ATP 16.6667
403 5C2N NAG 16.6667
404 2V7Q ADP 16.6667
405 3PCR GTP 16.8142
406 3Q9L ATP 16.8142
407 5Z69 AGS 16.8142
408 6FAA ADP 16.8142
409 1AKY AP5 16.8142
410 6B8B ADP 16.8142
411 2PNZ 5GP 16.8142
412 5W97 CHD 17.0213
413 1RRC ADP 17.1429
414 1NJF ADP 17.1429
415 1NJF AGS 17.1429
416 5KDO GDP 17.5676
417 1CS4 GSP 17.6991
418 6AU6 GDP 17.6991
419 3TBK ANP 17.6991
420 5Y6N ADP 17.6991
421 2RGX AP5 17.6991
422 3AI8 HNQ 17.6991
423 2IDO TMP 17.6991
424 5YT0 GDP 17.7143
425 5FG3 GDP 17.7143
426 4XGU ADP 17.7143
427 5EXT ADP 17.7143
428 2GJ8 ALF GDP 18.0233
429 2XTZ GSP 18.2857
430 1KJ8 GAR 18.2857
431 6CRK GDP 18.3099
432 1GP2 GDP 18.3099
433 3EWA ANP 18.5841
434 2GDJ ANP 18.5841
435 3FYH ADP 18.5841
436 2ZR9 DTP 18.8571
437 3A4M ADP 19.4286
438 3IIJ ADP 19.4286
439 3TK1 GDP 19.469
440 5FTB ANP 19.469
441 1VKJ A3P 19.469
442 4R98 GNH 19.5572
443 1KK8 BEF ADP 20
444 1B7T ADP 20
445 5MZN ADP 20
446 3VMF GTP 20.354
447 3WXM GTP 20.354
448 5FHD ADP ALF 20.354
449 1SQ5 ADP 20.5714
450 1LVK MNT BEF 20.5714
451 2WIC GNP 20.5993
452 1G6H ADP 21.2389
453 4X8O AP5 21.2389
454 4CP8 MLI 21.7143
455 4ZKD GDP 22.1239
456 4LC1 GDP 22.2857
457 3COB ADP 22.2857
458 3EC1 GDP 22.8571
459 4A4Z ANP 22.8571
460 4IEE AGS 23.0089
461 6B4K ANP 23.4286
462 3T12 GDP ALF 23.8938
463 2HIM ASN 23.8938
464 2ZPA ADP 24.5714
465 3L6C MLI 24.5714
466 1OYY AGS 24.7788
467 4GOJ GNP 25.1429
468 4ZI2 GNP 25.1429
469 4IDN GNP 25.1429
470 4KBF AMP 25.6637
471 4V0K GDP 26.0355
472 2XTN GTP 26.2857
473 5BN3 ADP 26.2857
474 1SKQ GDP 26.5487
475 1H65 GDP 26.5487
476 3ZIA ADP 26.5487
477 3MD0 GDP 26.5487
478 3ZIA ATP 26.5487
479 3DKP ADP 26.5487
480 6H45 QEI 26.5487
481 1P72 ADP 26.5487
482 1WF3 GNP 27.4286
483 3DZD ADP 27.4336
484 1HTW ADP 27.8481
485 3DOE GTP 28
486 3AQ4 GDP 28
487 1JJV ATP 28
488 3DEF GDP 28.3186
489 2O0J ADP 28.3186
490 2PL3 ADP 30.0885
491 5DI3 GNP 30.2857
492 5KUT GDP 30.2857
493 2X77 GDP 31.4286
494 2Z5F A3P 31.8584
495 1YRB GDP 32
496 6FX2 FUC C4W NAG BMA MAN NAG GAL 32.5581
497 1YZG GDP 32.5714
498 3CX8 GSP 32.7434
499 3AB3 GDP 32.7434
500 1ZCB GDP 32.7434
501 1KSH GDP 33.1429
502 1M2O GNP 33.1429
503 1RE0 GDP 33.5366
504 1S9D GDP 33.5366
505 2A5F GTP 33.7143
506 2ZEJ GDP 33.7143
507 2J59 GTP 33.7349
508 1O3Y GTP 33.7349
509 1J2J GTP 33.7349
510 1NRJ GTP 34.4037
511 2QTV GNP 34.7305
512 4KAX GTP 35.503
513 1X6V ADP 36.2832
514 2W83 GTP 36.3636
515 3N5C GDP 36.4198
516 5M04 GDP 37.1429
517 1MKY GDP 37.7143
518 1ZJ6 G3D 38.2857
519 1K6M AGS 38.2857
520 1R4A GNP 39.3939
521 5EE5 GTP 39.7661
522 4YLG GDP 39.8844
523 1ZD9 GDP 40.5714
524 1F6B GDP 42.2857
525 3REF GDP 42.8571
526 5OEC GDP 42.8571
527 1A4R GNH 45.1429
528 1A4R GDP 45.1429
529 1GRN GDP 45.7143
530 4YC7 GNP 45.7143
531 4ITR GDP 45.7143
532 1GRN AF3 45.7143
533 2NGR GDP 45.7143
534 2WMO GTP 45.7143
535 4DID GDP 45.7143
536 2NGR AF3 45.7143
537 1NF3 GNP 46.2857
538 5UPK GNP 46.2857
539 3GJ7 GDP 46.8571
540 3E5H GNP 46.8571
541 3GJ4 GDP 46.8571
542 3GJ5 GDP 46.8571
543 3GJ8 GDP 46.8571
544 3GJ0 GDP 47.4286
545 3GJ3 GDP 47.4286
546 5DIF GNP 47.4286
547 5UWJ GNP 47.4286
548 5UWP GNP 47.4286
549 4HAT GNP 47.4286
550 5UWI GNP 47.4286
551 5UWW GNP 47.4286
552 5UWR GNP 47.4286
553 5UWQ GNP 47.4286
554 6CIT GNP 47.4286
555 5UWU GNP 47.4286
556 5UWO GNP 47.4286
557 5UWT GNP 47.4286
558 5BXQ GDP 47.4286
559 5DHF GNP 47.4286
560 1WA5 GTP 47.4286
561 5UWH GNP 47.4286
562 5UWS GNP 47.4286
563 1IBR GNP 47.4286
564 5DI9 GNP 47.4286
565 4U5X GNP 47.4286
566 2J0V GDP 48
567 3GJX GTP 48
568 1TX4 ALF GDP 48.5714
569 5HPY GDP 48.5714
570 5JCP GDP ALF 48.5714
571 5IRC GDP 48.5714
572 4XSH GSP 48.5714
573 1CXZ GSP 48.5714
574 2W2X GSP 48.5714
575 1OW3 GDP 48.5714
576 3RAB GNP 49.1124
577 3SBD GNP 49.1429
578 4D0N GDP 49.1429
579 6BCB GSP 49.1429
580 6BCA GSP 49.1429
581 2GCO GNP 49.1429
582 3LXR GDP 49.1429
583 4XOI GTP 49.1429
584 1KMQ GNP 49.1429
585 2FJU GSP 49.1429
586 6BC0 GSP 49.1429
587 2GCN GDP 49.1429
Pocket No.: 2; Query (leader) PDB : 1ZC3; Ligand: GNP; Similar sites found with APoc: 33
This union binding pocket(no: 2) in the query (biounit: 1zc3.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1SQL GUN None
2 5BSH PRO 3.42857
3 1A78 TDG 3.73134
4 1LNX URI 4.93827
5 3FSY SCA 5.71429
6 1UJ2 ADP 5.71429
7 4QAG F95 6.01504
8 5C9P FUC 6.19469
9 2P3V SRT 6.19469
10 3KIF GDL 6.60377
11 1LK7 DER 6.85714
12 1VBO MAN 7.07965
13 5XLS URA 7.07965
14 1VBO MAN MAN MAN 7.07965
15 2B4B COA 7.07965
16 1NHX FTB 7.07965
17 4WEI GLC GAL 7.42857
18 2D3N GLC GLC GLC 7.9646
19 2Z48 NGA 8
20 4ZU4 4TG 8.10811
21 5SXS NIZ 8.57143
22 4BFW ZVW 8.84956
23 4LXQ TYD 9.14286
24 4LXQ FON 9.14286
25 4MDB RLT 9.71429
26 5UIJ TYD 9.71429
27 5TCI MLI 9.71429
28 1NT4 G1P 12.3894
29 3KIH GDL 16.4948
30 5VNB ALA THR ALY ALA ALA ARG ALY SER ALA PRO 17.5676
31 4LZB URA 18.8571
32 4BGB ADP 21.1429
33 1T3D CYS 30.9735
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