Receptor
PDB id Resolution Class Description Source Keywords
1YFZ 2.2 Å EC: 2.4.2.8 NOVEL IMP BINDING IN FEEDBACK INHIBITION OF HYPOXANTHINE-GUA PHOSPHORIBOSYLTRANSFERASE FROM THERMOANAEROBACTER TENGCONGE THERMOANAEROBACTER TENGCONGENSIS PROTEIN-NUCLEOTIDE COMPLEX TRANSFERASE
Ref.: ALTERNATIVE IMP BINDING IN FEEDBACK INHIBITION OF HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE FROM THERMOANAEROBACTER TENGCONGENSIS. J.MOL.BIOL. V. 348 1199 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:1200;
B:2200;
Invalid;
Invalid;
none;
none;
submit data
59.044 C2 H3 O2 CC(=O...
IMP A:1210;
B:2210;
Valid;
Valid;
none;
none;
Ki = 45 uM
348.206 C10 H13 N4 O8 P c1nc2...
MG A:1191;
A:1192;
B:2191;
B:2192;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YFZ 2.2 Å EC: 2.4.2.8 NOVEL IMP BINDING IN FEEDBACK INHIBITION OF HYPOXANTHINE-GUA PHOSPHORIBOSYLTRANSFERASE FROM THERMOANAEROBACTER TENGCONGE THERMOANAEROBACTER TENGCONGENSIS PROTEIN-NUCLEOTIDE COMPLEX TRANSFERASE
Ref.: ALTERNATIVE IMP BINDING IN FEEDBACK INHIBITION OF HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE FROM THERMOANAEROBACTER TENGCONGENSIS. J.MOL.BIOL. V. 348 1199 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 12 families.
1 1YFZ Ki = 45 uM IMP C10 H13 N4 O8 P c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 1YFZ Ki = 45 uM IMP C10 H13 N4 O8 P c1nc2c(n1[....
50% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1PZM - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
2 5KAM Ki = 77.3 uM IMP C10 H13 N4 O8 P c1nc2c(n1[....
3 5JSQ Ki = 21.3 uM 6MS C11 H18 N5 O4 P c1nc2c(n1C....
4 4RHY Ki = 1.13 uM 3QG C15 H29 N6 O10 P3 c1nc2c(n1C....
5 4RHX Ki = 1.6 uM 3QF C15 H27 N7 O8 P2 c1nc2c(n1C....
6 1HGX - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
7 1I0L - PRP C5 H13 O14 P3 C([C@@H]1[....
8 1TC2 - PRP C5 H13 O14 P3 C([C@@H]1[....
9 1I0I - PRP C5 H13 O14 P3 C([C@@H]1[....
10 1P19 Kd = 76.8 uM IMP C10 H13 N4 O8 P c1nc2c(n1[....
11 1P18 - PRP C5 H13 O14 P3 C([C@@H]1[....
12 1TC1 ic50 > 2 mM FMB C10 H12 N4 O5 C1=Nc2c(n[....
13 1I14 - PRP C5 H13 O14 P3 C([C@@H]1[....
14 1I13 - PRP C5 H13 O14 P3 C([C@@H]1[....
15 3ACD - IMP C10 H13 N4 O8 P c1nc2c(n1[....
16 3ACC - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
17 1YFZ Ki = 45 uM IMP C10 H13 N4 O8 P c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: IMP; Similar ligands found: 76
No: Ligand ECFP6 Tc MDL keys Tc
1 IMP 1 1
2 IDP 0.824324 0.986111
3 NOS 0.724638 0.835616
4 5GP 0.609756 0.972603
5 G 0.609756 0.972603
6 DI 0.578313 0.92
7 SIB 0.549451 0.772152
8 93A 0.523256 0.841463
9 GDP 0.505495 0.959459
10 GP3 0.494505 0.934211
11 C2R 0.493827 0.891892
12 GTP 0.489362 0.959459
13 GP2 0.48913 0.922078
14 GNH 0.483871 0.946667
15 G2P 0.479167 0.922078
16 AMZ 0.47561 0.90411
17 SNI 0.475 0.8
18 GMV 0.473684 0.934211
19 GAV 0.469388 0.922078
20 G1R 0.46875 0.946667
21 GCP 0.46875 0.934211
22 AIR 0.468354 0.888889
23 NIA 0.464286 0.835443
24 GNP 0.463918 0.934211
25 GSP 0.463918 0.910256
26 GDP MG 0.463158 0.909091
27 A 0.458824 0.90411
28 1RB 0.458824 0.847222
29 AMP 0.458824 0.90411
30 ALF 5GP 0.458333 0.875
31 GDP BEF 0.458333 0.886076
32 6SW 0.456522 0.930556
33 RBZ 0.453488 0.837838
34 GPG 0.45098 0.922078
35 7RP 0.448276 0.888889
36 GDC 0.447619 0.922078
37 GDD 0.447619 0.922078
38 GKE 0.447619 0.922078
39 GTP MG 0.444444 0.909091
40 BEF GDP 0.444444 0.875
41 7RA 0.443182 0.891892
42 IMO 0.443182 0.890411
43 JLN 0.443182 0.90411
44 AAM 0.443182 0.90411
45 P2P 0.443182 0.864865
46 RMB 0.443182 0.835616
47 FAI 0.443182 0.90411
48 G2R 0.441176 0.922078
49 GCP G 0.44 0.921053
50 G7M 0.43956 0.934211
51 XMP 0.438202 0.932432
52 IRN 0.435897 0.830986
53 Y9Z 0.433962 0.865854
54 PMO 0.433333 0.813333
55 71V 0.433333 0.825
56 GDP AF3 0.431373 0.875
57 GDP ALF 0.431373 0.875
58 GKD 0.431193 0.922078
59 JB2 0.431193 0.922078
60 GFB 0.429907 0.922078
61 GDR 0.429907 0.922078
62 6CK 0.425926 0.898734
63 G3A 0.425926 0.934211
64 YGP 0.424528 0.8875
65 G5P 0.422018 0.934211
66 PGS 0.419355 0.825
67 G G 0.419048 0.921053
68 RVP 0.416667 0.837838
69 GTG 0.416667 0.898734
70 GDX 0.414414 0.934211
71 GUO 0.41 0.931507
72 GMP 0.406977 0.84
73 U2G 0.405172 0.898734
74 2SA 0.40404 0.894737
75 6C6 0.402062 0.846154
76 GPD 0.401786 0.8875
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YFZ; Ligand: IMP; Similar sites found: 378
This union binding pocket(no: 1) in the query (biounit: 1yfz.bio2) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3S9K CIT 0.0004989 0.51066 None
2 1UO5 PIH 0.01136 0.42637 None
3 1OGZ EQU 0.00275 0.42129 None
4 1Y13 BIO 0.002902 0.41775 None
5 3H86 AP5 0.0377 0.40978 None
6 3RFV 15L 0.01502 0.40958 None
7 1OGD RIP 0.001885 0.40791 None
8 3RFV NAI 0.01834 0.40702 None
9 3GWT 066 0.0268 0.4032 None
10 3LTW HLZ 0.0006224 0.44302 1.46341
11 1HFA PIO 0.02737 0.43521 1.46341
12 3GD8 GOL 0.01464 0.40724 1.46341
13 5EQU AKG 0.01243 0.40087 1.46341
14 4BAS GNP 0.0007866 0.45767 1.50754
15 3TA2 ATP 0.02019 0.41164 1.69492
16 3TA2 AKG 0.01932 0.40728 1.69492
17 2ZWS PLM 0.00377 0.45137 1.95122
18 1UZN NAP 0.004997 0.41504 1.95122
19 4CCO OGA 0.001751 0.40583 1.95122
20 3NUG NAD 0.04423 0.40464 1.95122
21 3QDW A2G 0.01331 0.40638 2.0979
22 3U5S FAD 0.01427 0.40304 2.38095
23 3AHC TPP 0.0004587 0.48182 2.43902
24 4R33 TRP 0.001448 0.4634 2.43902
25 4R33 SAH 0.001448 0.4634 2.43902
26 1I2B UPG 0.009044 0.44534 2.43902
27 1I2B USQ 0.009044 0.44534 2.43902
28 1I2B NAD 0.009044 0.44534 2.43902
29 3CXO 1N5 0.003712 0.44223 2.43902
30 4COQ SAN 0.0009384 0.43561 2.43902
31 3IL6 B83 0.003072 0.43015 2.43902
32 2EB5 OXL 0.001875 0.42311 2.43902
33 1O0D 163 0.006175 0.41322 2.43902
34 1C4U IH1 0.009684 0.40773 2.43902
35 2I4O ATP 0.005267 0.40706 2.43902
36 3CXO 3LR 0.02141 0.40526 2.43902
37 2NW9 FT6 0.003832 0.40412 2.43902
38 2DUA OXL 0.0145 0.40103 2.43902
39 4C0X FMN 0.007228 0.42377 2.46305
40 4C0X AQN 0.02734 0.4028 2.46305
41 2V5E SCR 0.01987 0.4054 2.5
42 3F81 STT 0.0003212 0.48274 2.73224
43 2OYS FMN 0.0001553 0.48818 2.92683
44 1B8U OAA 0.0004574 0.4848 2.92683
45 1B8U NAD 0.0004139 0.46974 2.92683
46 3WO0 ALA 0.003429 0.44987 2.92683
47 3WO0 ADP 0.003429 0.44987 2.92683
48 2X61 CH 0.004485 0.44771 2.92683
49 3Q9T FAY 0.005037 0.44432 2.92683
50 3IOI 1GW 0.004872 0.43814 2.92683
51 1VDC FAD 0.01252 0.43393 2.92683
52 1XMV ADP 0.01418 0.43368 2.92683
53 2PTZ PAH 0.002173 0.43032 2.92683
54 3HZL 6PC 0.004322 0.4295 2.92683
55 1Q3Q ANP 0.02422 0.42589 2.92683
56 4KCF AKM 0.005464 0.42457 2.92683
57 1RYD GLC 0.00179 0.42394 2.92683
58 2HGS ADP 0.0063 0.42021 2.92683
59 1R18 SAH 0.007222 0.41762 2.92683
60 2J0W ADP 0.005301 0.41605 2.92683
61 4M51 BEZ 0.006021 0.41512 2.92683
62 1Y42 TYR 0.001095 0.415 2.92683
63 1WRA PC 0.00422 0.41496 2.92683
64 1BGQ RDC 0.01468 0.41003 2.92683
65 3BS8 PMP 0.005593 0.40845 2.92683
66 4G10 GSH 0.007516 0.40753 2.92683
67 4KCF FMN 0.007542 0.40747 2.92683
68 1FP1 HCC 0.009423 0.40731 2.92683
69 3BLI ACO 0.01299 0.40647 2.92683
70 1RRC ADP 0.01387 0.40521 2.92683
71 2CSN CKI 0.02055 0.40212 2.92683
72 3VKX T3 0.01562 0.40049 2.92683
73 1XE7 GUN 0.009464 0.41341 2.95567
74 1V2X SAM 0.003828 0.42603 3.09278
75 1YOA FMN 0.00909 0.43144 3.14465
76 1H8G CHT 0.005633 0.44228 3.15789
77 4AF5 CIT 0.004701 0.40649 3.15789
78 2FWP CIT 0.02022 0.4088 3.27869
79 4OYA 1VE 0.02196 0.44564 3.40426
80 2FPU HSO 0.001818 0.40149 3.40909
81 1H9G COA MYR 0.0005809 0.47248 3.41463
82 1OTH PAO 0.0008864 0.47176 3.41463
83 1LTH NAD 0.00379 0.46658 3.41463
84 2EFJ SAH 0.0008277 0.45036 3.41463
85 2DTX BMA 0.004216 0.44896 3.41463
86 4O1M NAD 0.003658 0.44119 3.41463
87 1B9I PXG 0.002718 0.43787 3.41463
88 2OZE AGS 0.002804 0.42989 3.41463
89 3TXO 07U 0.002173 0.428 3.41463
90 4M2K PLP 0.001515 0.42656 3.41463
91 1WUR 8DG 0.004651 0.42596 3.41463
92 2YYJ FAD 0.04412 0.4239 3.41463
93 2YYJ 4HP 0.04412 0.4239 3.41463
94 1RYI GOA 0.01538 0.42224 3.41463
95 2YIV NBN 0.003074 0.42092 3.41463
96 1YS4 NAP 0.006242 0.42038 3.41463
97 1V1A ADP 0.01028 0.41965 3.41463
98 2AMV BIN 0.02804 0.41863 3.41463
99 2EFJ 37T 0.002265 0.41646 3.41463
100 1DXY COI 0.008176 0.41642 3.41463
101 1PFK ADP 0.005346 0.4138 3.41463
102 5YAS FAC 0.004121 0.41146 3.41463
103 2YIV YIV 0.00735 0.4112 3.41463
104 1ZGA HMK 0.00501 0.41044 3.41463
105 2PWY SAH 0.0117 0.41003 3.41463
106 1T8U UAP SGN IDS SGN 0.03439 0.40536 3.41463
107 3F4F UMP 0.02031 0.40247 3.41463
108 3LIH RAF 0.01263 0.40184 3.41463
109 3VPQ GSH 0.00371 0.40469 3.43137
110 1JGS SAL 0.002287 0.46267 3.62319
111 1V2G OCA 0.001603 0.43104 3.68421
112 1Y1A GSH 0.02282 0.41292 3.82514
113 1ZN7 PRP 0.001281 0.46925 3.88889
114 1ZN7 ADE 0.0139 0.40504 3.88889
115 3ZRR PXG 0.0009329 0.45245 3.90244
116 2XVE FAD 0.0142 0.43988 3.90244
117 3ZGE ASP 0.002844 0.42984 3.90244
118 1HEX NAD 0.005981 0.42886 3.90244
119 2HGZ PBF 0.005568 0.42581 3.90244
120 1UBY DMA 0.003923 0.42162 3.90244
121 1NZY BCA 0.01078 0.41739 3.90244
122 1UXG NAD 0.01959 0.41684 3.90244
123 1UXG FUM 0.01959 0.41684 3.90244
124 2B7N NTM 0.001872 0.41659 3.90244
125 3V1U HXC 0.003305 0.41542 3.90244
126 1Z42 HBA 0.01825 0.41527 3.90244
127 4TMK T5A 0.01559 0.41512 3.90244
128 2C7G FAD 0.03925 0.41494 3.90244
129 4LSJ LSJ 0.008234 0.41344 3.90244
130 2CKM AA7 0.02783 0.4124 3.90244
131 2C7G ODP 0.04798 0.40998 3.90244
132 1Z42 FMN 0.0002752 0.4098 3.90244
133 1PEA ACM 0.00795 0.40966 3.90244
134 1CKN GTP 0.004141 0.4087 3.90244
135 1Z44 FMN 0.00028 0.40225 3.90244
136 3V1U NAD 0.02144 0.4013 3.90244
137 3BL6 FMC 0.004476 0.42119 3.91304
138 1SC3 MLI 0.00189 0.43785 3.93258
139 2VQ5 HBA 0.00575 0.40913 3.9801
140 3UEC ALA ARG TPO LYS 0.005706 0.40928 4.10959
141 4F8L GAL 0.00999 0.4293 4.13793
142 1I0Z OXM 0.00004636 0.52236 4.39024
143 1XHL NDP 0.0003052 0.49278 4.39024
144 2PT9 2MH 0.000961 0.47282 4.39024
145 2DKH 3HB 0.00138 0.47153 4.39024
146 2PT9 S4M 0.001395 0.45397 4.39024
147 1T26 NAI 0.01415 0.45375 4.39024
148 1T26 GBD 0.01415 0.45375 4.39024
149 1NN5 2DT 0.002313 0.45017 4.39024
150 1NN5 ANP 0.002313 0.45017 4.39024
151 2W1A TSA 0.0007037 0.44312 4.39024
152 1A69 FMB 0.01357 0.44085 4.39024
153 1EDO NAP 0.01675 0.43996 4.39024
154 2DKH FAD 0.004761 0.43982 4.39024
155 2YK7 CSF 0.002218 0.43625 4.39024
156 1C0I FAD 0.0108 0.43535 4.39024
157 1C0I BE2 0.0108 0.43535 4.39024
158 3CQ5 PMP 0.0002188 0.43174 4.39024
159 2QIA U20 0.0258 0.42218 4.39024
160 4HGP KDO 0.01452 0.41986 4.39024
161 1E7S NAP 0.01291 0.41885 4.39024
162 4G1V FAD 0.01094 0.4171 4.39024
163 4KGM ATP 0.0003418 0.40815 4.39024
164 3A8U PLP 0.01638 0.40509 4.39024
165 4C1K PEP 0.004964 0.40265 4.39024
166 3JDW ORN 0.001971 0.43211 4.49173
167 2D37 NAD 0.004611 0.43391 4.54545
168 2D37 FMN 0.004279 0.43391 4.54545
169 1SS4 GSH 0.0009853 0.49458 4.57516
170 1SS4 CIT 0.02315 0.44403 4.57516
171 1ULE GLA GAL NAG 0.005595 0.41656 4.66667
172 1TU3 GNP 0.0005591 0.47153 4.67836
173 3F8C HT1 0.004409 0.40168 4.7619
174 2J7T 274 0.0007453 0.47082 4.87805
175 1PL6 NAD 0.000909 0.45687 4.87805
176 1PL6 572 0.002014 0.45687 4.87805
177 1I7Z COC 0.0007469 0.44483 4.87805
178 1JA9 NDP 0.02225 0.43381 4.87805
179 1GSA ADP 0.01295 0.43323 4.87805
180 3RKR NAP 0.001238 0.43301 4.87805
181 2BZ1 TAU 0.01136 0.42637 4.87805
182 1O68 KIV 0.0005698 0.42588 4.87805
183 3IHB TRS 0.04049 0.41851 4.87805
184 1JA9 PYQ 0.01113 0.41808 4.87805
185 3PNL ADP 0.007429 0.41708 4.87805
186 2WQP WQP 0.01212 0.41374 4.87805
187 1CL2 PPG 0.009293 0.4094 4.87805
188 1ZFJ IMP 0.03511 0.40928 4.87805
189 1GSA GSH 0.01009 0.40604 4.87805
190 1VJT NAD 0.01164 0.40517 4.87805
191 2JFV FLC 0.00524 0.40452 4.87805
192 3SCH TB6 0.006221 0.40142 4.87805
193 2XRH NIO 0.002676 0.42353 5
194 3DCM SAM 0.01038 0.40732 5.20833
195 4NTD FAD 0.009787 0.4309 5.29412
196 4DQ2 BTX 0.0003415 0.48602 5.36585
197 1O9U ADZ 0.0005776 0.47073 5.36585
198 1X54 4AD 0.002659 0.43996 5.36585
199 4IOK XPO 0.006463 0.42137 5.36585
200 1RZM E4P 0.005932 0.40855 5.36585
201 4F2Q QUS 0.006817 0.40716 5.36585
202 4WBD ADP 0.007202 0.40489 5.36585
203 1XX4 BAM 0.01732 0.40095 5.36585
204 2ALG HP6 0.004177 0.42624 5.43478
205 2ALG DAO 0.004177 0.42624 5.43478
206 2F01 BTN 0.01197 0.44541 5.51181
207 2F01 BTQ 0.01197 0.44541 5.51181
208 9LDB OXM 0.00001481 0.56014 5.85366
209 9LDT OXM 0.00001587 0.55865 5.85366
210 3TKA CTN 0.002659 0.4604 5.85366
211 1OFH ADP 0.001006 0.46025 5.85366
212 4N02 FNR 0.005557 0.45404 5.85366
213 1V6A TRE 0.0002672 0.45044 5.85366
214 1KBJ FMN 0.002075 0.44633 5.85366
215 1WVG CXY 0.001751 0.44446 5.85366
216 4IVG ANP 0.01539 0.43121 5.85366
217 3U4C NDP 0.006066 0.42996 5.85366
218 2BGM NAJ 0.02266 0.42732 5.85366
219 2Q3M MLA 0.005582 0.42425 5.85366
220 3UR0 SVR 0.01785 0.42413 5.85366
221 1WVG APR 0.00833 0.41958 5.85366
222 1IYE PGU 0.02204 0.40708 5.85366
223 4W6Z ETF 0.01412 0.40517 5.85366
224 3RF4 FUN 0.00009828 0.45354 6.03448
225 5FIT AP2 0.0006816 0.44648 6.12245
226 1QJC PNS 0.03703 0.41451 6.32911
227 1R27 MGD 0.003419 0.44993 6.34146
228 1A8R GTP 0.001176 0.44811 6.34146
229 1I9G SAM 0.007768 0.44215 6.34146
230 4AQL TXC 0.00327 0.42498 6.34146
231 2XK9 XK9 0.01521 0.41785 6.34146
232 3U1T MLI 0.003884 0.41652 6.34146
233 3ZY6 GFB 0.007986 0.41401 6.34146
234 3FED BIX 0.009152 0.40593 6.34146
235 1YAG ATP 0.007928 0.41747 6.4
236 4DVE BTN 0.004671 0.40921 6.56566
237 3R35 4CO 0.005683 0.43385 6.62252
238 4BMO FMN 0.0008171 0.46424 6.72269
239 1JAC AMG 0.002776 0.44782 6.76692
240 1KOL NAD 0.002035 0.46032 6.82927
241 4PLG OXM 0.00272 0.45564 6.82927
242 4PLG NAI 0.00272 0.45564 6.82927
243 1SOW NAD 0.002716 0.44968 6.82927
244 2BLE 5GP 0.01249 0.44131 6.82927
245 2VJJ RAM GLC GAL NAG NAG GLC 0.009397 0.44111 6.82927
246 3MAG 3MA 0.004499 0.43744 6.82927
247 4GYW UDP 0.005959 0.43416 6.82927
248 3D3W NAP 0.005733 0.43368 6.82927
249 4B16 NAG 0.006398 0.42986 6.82927
250 3GE7 AFQ 0.008728 0.42779 6.82927
251 3L24 GOA 0.007284 0.41879 6.82927
252 3H22 B53 0.004353 0.41048 6.82927
253 3MCT 3MC 0.001709 0.40833 6.82927
254 1PR9 NAP 0.02441 0.40729 6.82927
255 2F7C CCU 0.003647 0.40499 6.82927
256 2IUW AKG 0.005302 0.40431 6.82927
257 3ZLM ANP 0.01105 0.40434 6.91489
258 3GM5 CIT 0.003692 0.41086 6.91824
259 3JQM GTP 0.002812 0.41558 7.00637
260 2X2T GAL NGA 0.001653 0.4492 7.18954
261 4P3H 25G 0.03504 0.41013 7.25389
262 1R37 NAD 0.003571 0.44673 7.31707
263 3TO7 COA 0.004576 0.44626 7.31707
264 3IB8 AMP 0.002962 0.42236 7.31707
265 4O8A 2OP 0.01189 0.40871 7.31707
266 2AEB ABH 0.02982 0.40381 7.31707
267 3WUD GLC GAL 0.007195 0.41162 7.35294
268 2XI7 XI7 0.0004425 0.49978 7.6087
269 2HMT NAI 0.001684 0.47547 7.80488
270 1DSS NAD 0.0007713 0.46535 7.80488
271 3O03 NAP 0.001645 0.45238 7.80488
272 4I71 AGV 0.001661 0.43962 7.80488
273 4USQ FAD 0.006428 0.43504 7.80488
274 4TSK NDP 0.01682 0.43364 7.80488
275 2YBQ UP2 0.0101 0.4282 7.80488
276 2ZJ5 ADP 0.001434 0.42122 7.80488
277 2YBQ SAH 0.006892 0.41501 7.80488
278 1NW5 SAM 0.007068 0.41454 7.80488
279 4HZX G39 0.02765 0.41075 7.80488
280 1CM8 ANP 0.01659 0.40906 7.80488
281 1QS0 TDP 0.01359 0.40225 7.80488
282 1C1L GAL BGC 0.004821 0.41245 8.0292
283 3PAK MAN 0.00806 0.40728 8.10811
284 2ZJ3 G6P 0.0002056 0.48072 8.29268
285 2H6B 3C4 0.009316 0.44472 8.29268
286 3QV9 QV7 0.0006151 0.43594 8.29268
287 1FDJ 13P 0.0007819 0.43177 8.29268
288 3UH0 TSB 0.003773 0.43163 8.29268
289 1JN2 SFP 0.03315 0.42496 8.29268
290 1UJ5 5RP 0.002686 0.42171 8.29268
291 4LWA Q13 0.01768 0.41988 8.29268
292 2OI2 DP6 0.006784 0.40495 8.29268
293 2NCD ADP 0.003842 0.40408 8.29268
294 2JE7 XMM 0.02414 0.40033 8.29268
295 1FDJ 2FP 0.008863 0.40011 8.29268
296 1U7Z PMT 0.01056 0.42401 8.40708
297 2HVW DCP 0.007483 0.40546 8.69565
298 3KJI ADP 0.0006071 0.45371 8.78049
299 4HZD COA 0.005225 0.44031 8.78049
300 4CCN OGA 0.001318 0.42947 8.78049
301 3C1O NAP 0.009459 0.41564 8.78049
302 2XDQ MGX 0.01295 0.40696 8.78049
303 4A6F SEP 0.007367 0.42683 9.16667
304 3FPZ AHZ 0.005225 0.46973 9.26829
305 3CQD ATP 0.004021 0.44778 9.26829
306 4QVH FLC 0.009303 0.43526 9.26829
307 3DAG FEG 0.01333 0.4105 9.26829
308 1OMZ UD2 0.03799 0.40764 9.26829
309 1SSQ CYS 0.04198 0.40753 9.26829
310 4IS0 1R4 0.01272 0.40686 9.26829
311 3ZPG 5GP 0.0001092 0.50483 9.7561
312 1SAZ ACP 0.01596 0.44431 9.7561
313 4RJK PYR 0.005294 0.44369 9.7561
314 3VHZ L2P GLC MAN SGA 0.01385 0.44318 9.7561
315 1QF5 GDP 0.01145 0.4358 9.7561
316 1QF5 RPL 0.01145 0.4358 9.7561
317 3VHZ SOG 0.02553 0.42732 9.7561
318 1PTR PRB 0.001948 0.4295 10
319 1L1Q 9DA 0.004783 0.44056 10.2151
320 1YOE RIB 0.005875 0.43058 10.2439
321 1WY7 SAH 0.01897 0.41337 10.2439
322 1KC7 PPR 0.005699 0.4093 10.2439
323 2OFV 242 0.04598 0.4061 10.2439
324 2YVF FAD 0.005101 0.46099 10.7317
325 2YVF NAD 0.005268 0.46099 10.7317
326 2C31 ADP 0.0151 0.44334 10.7317
327 2C31 TZD 0.01549 0.44334 10.7317
328 4NES UD1 0.001717 0.43901 10.7317
329 3K56 IS3 0.005196 0.41211 10.7317
330 4UBP HAE 0.01356 0.40316 10.7317
331 4DXJ 0M9 0.001799 0.42632 11.2195
332 2QDT I38 0.003949 0.41936 11.2195
333 3SQG COM 0.01538 0.41095 11.2195
334 3OIG NAD 0.02148 0.42976 11.2782
335 4LFL TG6 0.002531 0.4202 11.6279
336 2FXV 5GP 0.004183 0.44937 11.7073
337 1T0S BML 0.005218 0.41793 11.7073
338 3SUC ATP 0.04114 0.40168 11.7073
339 3CBG SAH 0.0008215 0.45049 12.1951
340 3U7Y FLC 0.04578 0.40287 12.1951
341 1BTN I3P 0.001888 0.47593 12.2642
342 1Y8O ADP 0.00463 0.40937 12.5
343 1NVU GTP 0.0336 0.4176 12.6506
344 2BO4 FLC 0.000945 0.44309 12.6829
345 3VPD ANP 0.003878 0.42764 12.6829
346 1T57 FMN 0.0007597 0.46026 13.1068
347 4PO2 ASN ARG LEU LEU LEU THR GLY 0.001332 0.44964 13.1707
348 4P05 4NS 0.003874 0.42943 13.1707
349 2WGC SIA GAL BGC 0.009112 0.43139 13.4503
350 1WGC SIA GAL BGC 0.01411 0.41281 13.4503
351 1JUV NDP 0.008764 0.42004 13.4715
352 1TDF NAP 0.004392 0.47002 13.6585
353 1TDF FAD 0.002648 0.46522 13.6585
354 3ZS7 ATP 0.003477 0.43148 14.1463
355 3GEG NAD 0.003872 0.4373 14.6341
356 1GAD NAD 0.001225 0.45808 15.6098
357 2GJ3 FAD 0.0062 0.42051 15.8333
358 1NU4 MLA 0.003534 0.45283 16.4948
359 3S2Y FMN 0.006569 0.41404 16.5829
360 2GSD NAD 0.002768 0.453 16.5854
361 1ZUW DGL 0.002271 0.41937 17.0732
362 3R51 MMA 0.003577 0.43338 18.125
363 3TFC PEP 0.001931 0.40729 19.0244
364 2IMP NAI 0.03898 0.4257 20
365 1DKU AP2 0.01928 0.40539 21.9512
366 2NLI LAC 0.01582 0.43064 22.9268
367 2NLI FMN 0.01582 0.43064 22.9268
368 4M5P MLA 0.0154 0.41092 22.9268
369 1FIQ FAD 0.003259 0.44855 23.4146
370 1XVV CCQ 0.004585 0.44726 23.4146
371 1FIQ MTE 0.01274 0.41671 23.4146
372 1FIQ SAL 0.01438 0.41671 23.4146
373 2O66 FLC 0.0008215 0.43091 25.1852
374 1RY2 AMP 0.0116 0.41319 25.8537
375 1M1B SPV 0.004589 0.40099 26.3415
376 2Q97 ATP 0.00508 0.42429 27.8049
377 2WE5 ADP 0.00415 0.41621 33.1707
378 4JLS 3ZE 0.0003722 0.47605 44.7368
Pocket No.: 2; Query (leader) PDB : 1YFZ; Ligand: IMP; Similar sites found: 53
This union binding pocket(no: 2) in the query (biounit: 1yfz.bio3) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4MWV BCZ 0.01576 0.42026 None
2 2AK5 ARG PRO PRO LYS PRO ARG PRO ARG 0.007665 0.41479 None
3 3N5O GSH 0.006941 0.41301 None
4 4INB 1F6 0.01217 0.40434 None
5 1KHT AMP 0.006429 0.40088 1.5625
6 2Q8H TF4 0.01099 0.41034 1.95122
7 2HV8 GTP 0.03709 0.40069 1.95122
8 3QDY A2G GAL 0.002812 0.43006 2.0979
9 3QDT A2G GAL 0.006851 0.41259 2.0979
10 4JP3 CIT 0.0007669 0.40263 2.43902
11 2Q8M AMP 0.0005986 0.40034 2.43902
12 1Y2W NAG 0.004293 0.40813 2.8169
13 1GJW GLC 0.007422 0.40433 2.92683
14 1UWZ THU 0.002413 0.4284 2.94118
15 2Q37 3AL 0.003158 0.40749 3.31492
16 4RNX FMN 0.003433 0.42901 3.41463
17 1RM4 NDP 0.03671 0.40534 3.41463
18 3WCS MAN NAG 0.002137 0.40305 3.41463
19 1II5 GLU 0.004141 0.40278 4.39024
20 2W3L DRO 0.01486 0.40412 4.86111
21 4RPM HXC 0.01446 0.4209 4.87805
22 1H2K OGA 0.006039 0.40196 4.87805
23 3IHB GLU 0.01627 0.40145 4.87805
24 3UIE ADX 0.007015 0.40663 5
25 4EKV BTN 0.02146 0.40987 5.03145
26 4UOH ADP 0.00597 0.4022 5.29801
27 1O6B ADP 0.03327 0.41121 5.32544
28 2GDZ NAD 0.006041 0.43136 5.36585
29 1RZM PEP 0.002064 0.40605 5.36585
30 3WQT ANP 0.02467 0.40592 5.36585
31 2P1M IHP 0.00841 0.41939 5.625
32 2IZ1 ATR 0.002869 0.41542 5.85366
33 2D2I NAP 0.03504 0.40085 6.34146
34 4AIG FLX 0.0005568 0.40877 6.96517
35 2ZE3 AKG 0.001372 0.42199 7.31707
36 3IO3 ADP 0.004845 0.41971 7.31707
37 1TIW TFB 0.02291 0.41365 7.31707
38 1TIW FAD 0.02291 0.41365 7.31707
39 1WTC ACP 0.008693 0.40135 7.31707
40 1SBZ FMN 0.01784 0.41243 7.61421
41 1XOC VAL ASP SER LYS ASN THR SER SER TRP 0.01642 0.42232 7.80488
42 1P9P SAH 0.01043 0.41064 7.80488
43 1D3V ABH 0.02217 0.40064 7.80488
44 2HVW DDN 0.009293 0.4015 8.69565
45 4LNL 2BK 0.006372 0.41057 9.26829
46 4LNL 2BO 0.006372 0.41057 9.26829
47 4LNL PLG 0.006812 0.40717 9.26829
48 4JCA CIT 0.01721 0.40852 9.58084
49 1H16 PYR 0.002643 0.43128 9.7561
50 4NES UDP 0.004599 0.41868 10.7317
51 2BNE U5P 0.003814 0.44483 11.2195
52 2OHV NHL 0.001019 0.41053 14.1463
53 3HY3 10F 0.01856 0.4012 14.1463
Pocket No.: 3; Query (leader) PDB : 1YFZ; Ligand: IMP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1yfz.bio1) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1YFZ; Ligand: IMP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1yfz.bio1) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Feedback