Receptor
PDB id Resolution Class Description Source Keywords
1WYV 2.4 Å EC: 1.4.4.2 CRYSTAL STRUCTURE OF GLYCINE DECARBOXYLASE (P-PROTEIN) OF TH CLEAVAGE SYSTEM, IN INHIBITOR-BOUND FORM THERMUS THERMOPHILUS ALPHA(2)BETA(2) TETRAMER RIKEN STRUCTURAL GENOMICS/PROTEOMIINITIATIVE RSGI STRUCTURAL GENOMICS OXIDOREDUCTASE
Ref.: STRUCTURE OF P-PROTEIN OF THE GLYCINE CLEAVAGE SYST IMPLICATIONS FOR NONKETOTIC HYPERGLYCINEMIA EMBO J. V. 24 1523 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLP AOA B:1475;
D:2475;
F:3475;
H:4475;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
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321.202 n/a P(=O)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1WYV 2.4 Å EC: 1.4.4.2 CRYSTAL STRUCTURE OF GLYCINE DECARBOXYLASE (P-PROTEIN) OF TH CLEAVAGE SYSTEM, IN INHIBITOR-BOUND FORM THERMUS THERMOPHILUS ALPHA(2)BETA(2) TETRAMER RIKEN STRUCTURAL GENOMICS/PROTEOMIINITIATIVE RSGI STRUCTURAL GENOMICS OXIDOREDUCTASE
Ref.: STRUCTURE OF P-PROTEIN OF THE GLYCINE CLEAVAGE SYST IMPLICATIONS FOR NONKETOTIC HYPERGLYCINEMIA EMBO J. V. 24 1523 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1WYV - PLP AOA n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1WYV - PLP AOA n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1WYV - PLP AOA n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PLP AOA; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 PLP AOA 1 1
2 PLP GLY 0.561644 0.857143
3 AKB PLP 0.512821 0.828125
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1WYV; Ligand: PLP AOA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1wyv.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1WYV; Ligand: PLP AOA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1wyv.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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