Receptor
PDB id Resolution Class Description Source Keywords
1WYV 2.4 Å EC: 1.4.4.2 CRYSTAL STRUCTURE OF GLYCINE DECARBOXYLASE (P-PROTEIN) OF TH CLEAVAGE SYSTEM, IN INHIBITOR-BOUND FORM THERMUS THERMOPHILUS ALPHA(2)BETA(2) TETRAMER RIKEN STRUCTURAL GENOMICS/PROTEOMIINITIATIVE RSGI STRUCTURAL GENOMICS OXIDOREDUCTASE
Ref.: STRUCTURE OF P-PROTEIN OF THE GLYCINE CLEAVAGE SYST IMPLICATIONS FOR NONKETOTIC HYPERGLYCINEMIA EMBO J. V. 24 1523 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLP AOA B:1475;
D:2475;
F:3475;
H:4475;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
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321.202 n/a P(=O)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1WYV 2.4 Å EC: 1.4.4.2 CRYSTAL STRUCTURE OF GLYCINE DECARBOXYLASE (P-PROTEIN) OF TH CLEAVAGE SYSTEM, IN INHIBITOR-BOUND FORM THERMUS THERMOPHILUS ALPHA(2)BETA(2) TETRAMER RIKEN STRUCTURAL GENOMICS/PROTEOMIINITIATIVE RSGI STRUCTURAL GENOMICS OXIDOREDUCTASE
Ref.: STRUCTURE OF P-PROTEIN OF THE GLYCINE CLEAVAGE SYST IMPLICATIONS FOR NONKETOTIC HYPERGLYCINEMIA EMBO J. V. 24 1523 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1WYV - PLP AOA n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1WYV - PLP AOA n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1WYV - PLP AOA n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: PLP AOA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 PLP AOA 1 1
2 AKB PLP 0.512821 0.828125
Similar Ligands (3D)
Ligand no: 1; Ligand: PLP AOA; Similar ligands found: 41
No: Ligand Similarity coefficient
1 PDA 0.9641
2 PDD 0.9569
3 PLP GLY 0.9523
4 EPC 0.9482
5 GLY PLP 0.9477
6 DCS 0.9459
7 0JO 0.9442
8 IK2 0.9427
9 PLG 0.9423
10 IN5 0.9409
11 PLP PUT 0.9359
12 F0G 0.9321
13 PLI 0.9316
14 PP3 0.9296
15 AN7 0.9239
16 LCS 0.9231
17 PMH 0.9221
18 C6P 0.9181
19 OJQ 0.9179
20 KOU 0.9147
21 FOO 0.9137
22 PLS 0.9130
23 PLP SER 0.9129
24 7TS 0.9109
25 PLP CYS 0.9096
26 4LM 0.9061
27 PLP ABU 0.9042
28 L7N 0.9027
29 6DF 0.9014
30 P3D 0.8897
31 CKT 0.8871
32 PLP ALO 0.8861
33 EXT 0.8830
34 PLP 2KZ 0.8827
35 PSZ 0.8745
36 7XF 0.8745
37 PY5 0.8714
38 HM5 0.8708
39 TLP 0.8704
40 ILP 0.8664
41 2BK 0.8639
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1WYV; Ligand: PLP AOA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1wyv.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1WYV; Ligand: PLP AOA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1wyv.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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