Receptor
PDB id Resolution Class Description Source Keywords
1WMS 1.25 Å NON-ENZYME: TRANSPORT HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN RAB9 GTPASE: A NOVEL ANTIVIRAL DRUG TARGET HOMO SAPIENS GTPASE PROTEIN TRANSPORT
Ref.: HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN RAB9 GTPASE: A NOVEL ANTIVIRAL DRUG TARGET J.BIOL.CHEM. V. 279 40204 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:1001;
B:1002;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1S8F 1.77 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF RAB9 COMPLEXED TO GDP REVEALS A DIMER WITH AN ACTIVE CONFORMATION OF SWITCH II CANIS LUPUS FAMILIARIS INTRACELLULAR TRANSPORT VESICULAR TRAFFICKING HEMIHEDRAL TWINNING PROTEIN TRANSPORT
Ref.: CRYSTAL STRUCTURE OF RAB9 COMPLEXED TO GDP REVEALS A DIMER WITH AN ACTIVE CONFORMATION OF SWITCH II. FEBS LETT. V. 568 23 2004
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1S8F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1YZL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 1WMS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 175 families.
1 1S8F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1YZL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 1WMS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (274)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 149 families.
1 1Z2A - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1Z22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1YZT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1YZU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 1Z08 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 1Z0I - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4DKX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 2Y8E - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 2A5J - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 4LHW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4LHV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 2P2L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 2W2V - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
14 1MH1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
15 2WKP - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
16 2WKR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
17 2WKQ - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
18 5WDO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
19 3TGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
20 1P2T - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
21 4Q01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
22 4M21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
23 6ARK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
24 821P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
25 1Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
26 5VPZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
27 6F76 - CVK C24 H26 N2 O3 CN(C)Cc1cc....
28 6Q21 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
29 4L9W - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
30 4WA7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
31 3V4F - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
32 3K9N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
33 5OCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
34 4M1T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
35 4XVQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
36 5V71 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
37 5VP7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
38 2QUZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
39 1CLU Kd = 5.4 nM DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
40 4L8G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
41 5VBM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
42 2RGD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
43 4PZY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
44 4LPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
45 4DLV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
46 4LRW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
47 2CLD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
48 4M1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
49 3L8Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50 3LBH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
51 721P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
52 1LF5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
53 1GNR - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
54 4LUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
55 2RGE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
56 4DLS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
57 4M22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
58 4DLY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
59 1ZW6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
60 2RGC - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
61 5VQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
62 5V9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
63 2CL0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
64 4TQA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
65 3RRZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
66 5VPY - 9GM C10 H17 N6 O13 P3 c1nc2c(n1[....
67 2EVW - XY2 C12 H15 N5 O4 CC(=O)N(C)....
68 2RGB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
69 4LDJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70 1XJ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
71 1ZVQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
72 5VQ6 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
73 1P2S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
74 5V6V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
75 621P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
76 1P2V - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
77 2CL7 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
78 3OIW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
79 4LV6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
80 4DLT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
81 1P2U - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
82 5V6S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
83 5UK9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
84 6ASE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
85 3RS0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
86 5B30 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
87 5B2Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
88 3KKN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
89 4M1O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
90 5VQ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
91 4M1Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
92 5VPI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
93 5W22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
94 3I3S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
95 4OBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
96 3RRY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
97 1QRA - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
98 6BP1 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
99 4LYJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
100 121P - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
101 1RVD - DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
102 5VBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
103 2RGA - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
104 3RS7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
105 5UHV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
106 2CLC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
107 4EPT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
108 4EPY Kd = 340 uM 0QY C21 H21 N5 O c1ccc2c(c1....
109 4DLZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
110 1AGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
111 1GNQ - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
112 2Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
113 3RS2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
114 5VQ8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
115 4L9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
116 6B0Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
117 4M1S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
118 4EPV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
119 5WDP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
120 4TQ9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
121 3K8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
122 3OIV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
123 5OCT - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
124 5VBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
125 4Q02 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
126 3LBI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
127 3RSL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
128 1LF0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
129 1XCM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
130 421P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
131 4DLR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
132 2CE2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
133 4QL3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
134 4Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
135 4DLU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
136 1CTQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
137 3OIU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
138 6B0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
139 3RS5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
140 4EPW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
141 5WDQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
142 1IOZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
143 221P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
144 4LYH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
145 4DLX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
146 4Q03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
147 4PZZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
148 3KKM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
149 1JAI - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
150 3L8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
151 3RS4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
152 3LBN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
153 4NMM - Y9Z C14 H22 N6 O12 P2 CC(=O)NCCO....
154 5VQ2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
155 3RSO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
156 4XVR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
157 5P21 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
158 5F2E - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
159 4EPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
160 4EPR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
161 4DLW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
162 5WHD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
163 5V9O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
164 5V9U - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
165 2RGG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
166 4LYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
167 1JAH - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
168 1YU9 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
169 2BME - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
170 2BMD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
171 1YZN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
172 3RWM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
173 3RWO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
174 3REG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
175 2F9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
176 2F9M - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
177 1YZK - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
178 1OIV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
179 2FE4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
180 2FFQ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
181 2E9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
182 5US4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
183 5UQW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
184 5USJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
185 3NKV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
186 1HUQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
187 1Z07 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
188 1N6R - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
189 1Z0D - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
190 1N6H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
191 1N6P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
192 1N6K - GDP AF3 n/a n/a
193 1N6N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
194 1N6I - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
195 1R2Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
196 1N6L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
197 1N6O - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
198 1TU4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
199 1EK0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
200 1S8F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
201 1YZL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
202 1WMS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
203 1D5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
204 1Z0F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
205 3E5H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
206 4DSU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
207 4DST - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
208 4DSO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
209 4DSN - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
210 5OCG - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
211 1KAO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
212 3RAP - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
213 1YZQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
214 2GIL - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
215 1Z0A - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
216 1KY2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
217 1KY3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
218 2HT6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
219 3KKO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
220 3KKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
221 3KKP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
222 1X1R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
223 1X1S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
224 1T91 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
225 1VG8 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
226 2GCP - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
227 2GCN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
228 3X1Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
229 3X1Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
230 3X1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
231 3X1X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
232 4Z8Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
233 1G17 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
234 1G16 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
235 1M7B - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
236 2DPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
237 3Q7Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
238 3Q7P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
239 3Q72 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
240 1U8Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
241 1U90 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
242 1U8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
243 1YVD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
244 5WDR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
245 5WDS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
246 1Z06 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
247 3TH5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
248 3SBD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
249 1OIX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
250 1OIW - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
251 2QRZ - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
252 1A4R Kd = 9.4 pM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
253 1KMQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
254 1DPF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
255 1FTN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
256 5A0F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
257 1A2B - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
258 4U5X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
259 3Q85 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
260 1RYH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
261 1RYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
262 1VG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
263 5XC5 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
264 5XC3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
265 3RAB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
266 1GWN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
267 2EW1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
268 4O25 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
269 4O2R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
270 4O2L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
271 6BSX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
272 5YXH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
273 1XTQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
274 3SEA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: 93
This union binding pocket(no: 1) in the query (biounit: 1s8f.bio3) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 5W7Q GDP 3.9548
2 1MKY GDP 4.51977
3 1SKQ GDP 4.51977
4 1SVI GDP 4.51977
5 3WXM GTP 4.51977
6 3WYA GDP 5.08475
7 4HI0 GDP 5.08475
8 4ZKD GDP 5.64972
9 4DCT GDP 6.21469
10 5GOE GDP 7.34463
11 1SVK ALF GDP 7.9096
12 6CRK GDP 7.9096
13 6AU6 GDP 7.9096
14 2OM2 GDP 7.9096
15 3CX8 GSP 7.9096
16 1GP2 GDP 7.9096
17 1TAD ALF 7.9096
18 1TAD GDP 7.9096
19 1Y3A GDP 7.9096
20 3VMF GTP 7.9096
21 1D2E GDP 7.9096
22 4J0Q GDP 7.9096
23 1BH2 GSP 7.9096
24 3EC1 GDP 7.9096
25 1ZCB GDP 8.47458
26 1PUJ GNP 8.47458
27 3U6B GDP 8.88325
28 4G5G GDP 8.88325
29 5JBQ GDP 8.88325
30 4P3Y GDP 8.88325
31 3U6K GDP 8.88325
32 4PC3 GDP 8.88325
33 1D8T GDP 8.90585
34 2BVN GNP 8.90585
35 1TQ4 GDP 9.03955
36 1WF3 GNP 9.03955
37 2ODE ALF GDP 9.21986
38 2RCN GDP 9.60452
39 3MD0 GDP 10.1695
40 2HCJ GDP 10.4478
41 3TK1 GDP 10.7345
42 4RD0 GDP 11.2994
43 2QN6 GDP 11.2994
44 5W75 GDP 13.5593
45 2C78 GNP 14.1243
46 4B47 GDP 15.427
47 6G14 G4P 16.3842
48 1YRB GDP 18.0791
49 5KDO GDP 18.9189
50 1GOT GDP 19.1781
51 4NCN GTP 20.904
52 1G7S GDP 21.4689
53 5FG3 GDP 24.2938
54 3WY9 GDP 25
55 1KSH GDP 25.4237
56 3DOE GTP 25.4237
57 5XKT GNP 27.1186
58 4ZI2 GNP 29.3785
59 1FZQ GDP 29.3785
60 5HCN GCP 29.9435
61 3AQ4 GDP 30.5085
62 2GJ8 ALF GDP 30.814
63 2A5F GTP 30.8571
64 4KAX GTP 31.3609
65 2X77 GDP 31.6384
66 5M04 GDP 31.6384
67 2W83 GTP 32.1212
68 3PCR GTP 32.716
69 4M9Q GNP 32.7684
70 1MR3 G3D 33.3333
71 5KUT GDP 34.4633
72 2ZEJ GDP 34.4633
73 5YT0 GDP 37.8531
74 2J59 GTP 37.9518
75 4V0K GDP 38.4615
76 4YLG GDP 40.4624
77 1UPT GTP 40.9357
78 5EE5 GTP 41.5205
79 3T5G GDP 46.3277
80 4XOI GTP 46.8927
81 4XSH GSP 47.4576
82 1OW3 GDP 47.4576
83 5HPY GDP 47.4576
84 1TX4 ALF GDP 47.4576
85 1CXZ GSP 47.4576
86 2GCO GNP 47.4576
87 2CJW GDP 48.0226
88 6BCB GSP 48.0226
89 6BCA GSP 48.0226
90 4D0N GDP 48.0226
91 6BC0 GSP 48.0226
92 3LXR GDP 49.7175
93 3REF GDP 49.7175
Pocket No.: 2; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1s8f.bio3) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1s8f.bio3) has 28 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1s8f.bio3) has 28 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1s8f.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1s8f.bio4) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1s8f.bio4) has 28 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1s8f.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 1s8f.bio5) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 1S8F; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 1s8f.bio5) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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