Receptor
PDB id Resolution Class Description Source Keywords
1WG8 2 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF A PREDICTED S-ADENOSYLMETHIONINE- DEPENDENT METHYLTRANSFERASE TT1512 FROM THERMUS T HERMOPHILUS HB8. THERMUS THERMOPHILUS S-ADENOSYL-METHYLTRANSFERASE MRAW THERMUS THERMOPHILUS RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI STRUCTURAL GENOMICS
Ref.: CRYSTAL STRUCTURE OF A PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE TT1512 FROM THERMUS THERMOPHILUS HB8 AT 2.0 ANG. RESOLUTION. TO BE PUBLISHED
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:3142;
B:3141;
Valid;
Valid;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1WG8 2 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF A PREDICTED S-ADENOSYLMETHIONINE- DEPENDENT METHYLTRANSFERASE TT1512 FROM THERMUS T HERMOPHILUS HB8. THERMUS THERMOPHILUS S-ADENOSYL-METHYLTRANSFERASE MRAW THERMUS THERMOPHILUS RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI STRUCTURAL GENOMICS
Ref.: CRYSTAL STRUCTURE OF A PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE TT1512 FROM THERMUS THERMOPHILUS HB8 AT 2.0 ANG. RESOLUTION. TO BE PUBLISHED
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 57 families.
1 1WG8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 50 families.
1 1WG8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3TKA - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
4 1WG8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1WG8; Ligand: SAM; Similar sites found: 262
This union binding pocket(no: 1) in the query (biounit: 1wg8.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1PTR PRB 0.02923 0.40675 None
2 5C2N NAG 0.03349 0.40256 None
3 2AOT SAH 0.0001019 0.50051 1.40351
4 4RDH AMP 0.0012 0.45113 1.40351
5 4RDI ATP 0.001846 0.43432 1.40351
6 1JQD SAH 0.001162 0.40075 1.40351
7 2DPM SAM 0.00000005498 0.61151 1.40845
8 4D79 ATP 0.001678 0.43614 1.44928
9 2P41 SAH 0.000003656 0.55367 1.75439
10 5JJR SAH 0.000004103 0.55145 1.75439
11 2O07 MTA 0.0001081 0.44766 1.75439
12 2O07 SPD 0.0001306 0.43387 1.75439
13 1T5C ADP 0.02406 0.41113 1.75439
14 1WUU GLA 0.03245 0.40244 1.75439
15 3EVG SAH 0.000001433 0.57162 1.81818
16 2XVM SAH 0.0006109 0.46958 2.01005
17 3VSE SAH 0.000008403 0.56458 2.10526
18 1NW5 SAM 0.000005265 0.54057 2.10526
19 1F3L SAH 0.000006669 0.5249 2.10526
20 4UCI SAM 0.0001683 0.4755 2.10526
21 2PT9 S4M 0.0001947 0.45 2.10526
22 1V6A TRE 0.02527 0.40897 2.10526
23 2PT9 2MH 0.0003146 0.40434 2.10526
24 5FPE 3TR 0.03906 0.40098 2.10526
25 2I7C AAT 0.0005313 0.40192 2.12014
26 1HGX 5GP 0.02336 0.4058 2.18579
27 2PHT MAN MAN MAN 0.02317 0.41018 2.38095
28 1RTF BEN 0.02883 0.4065 2.38095
29 1Q8S MAN MMA 0.02716 0.40564 2.38095
30 1Q8O MAN MMA 0.02929 0.40468 2.38095
31 1Q8V MAN MAN 0.02733 0.40263 2.38095
32 2PHU MAN MAN 0.02799 0.40194 2.38095
33 2UYQ SAM 0.0005665 0.49825 2.45614
34 5F8F SFG 0.0001954 0.48747 2.45614
35 1E5Q SHR 0.009865 0.41643 2.45614
36 1ZX5 LFR 0.02834 0.40309 2.45614
37 3TKY SAH 0.001722 0.40244 2.45614
38 2WA2 SAM 0.000004845 0.5547 2.53623
39 1XCL SAH 0.000005652 0.47285 2.55319
40 1KYQ NAD 0.001822 0.43857 2.55474
41 3RKR NAP 0.004981 0.43525 2.67176
42 1G55 SAH 0.00000006019 0.62455 2.80702
43 4KIB SAH 0.000001627 0.57606 2.80702
44 5X62 SAH 0.00003057 0.51863 2.80702
45 5KVA SAM 0.00000949 0.51853 2.80702
46 4KRG SAH 0.00003615 0.51535 2.80702
47 5AHO TLA 0.0004003 0.51216 2.80702
48 5KOK SAH 0.00007928 0.48964 2.80702
49 1Y8Q ATP 0.0004389 0.44181 2.80702
50 2Q28 ADP 0.001183 0.43888 2.80702
51 1JS8 MAN MAN BMA 0.01053 0.42248 2.80702
52 2OG2 MLI 0.01156 0.42211 2.80702
53 2ZZV LAC 0.02749 0.40426 2.80702
54 3B9Q MLI 0.03613 0.40184 2.80702
55 1Z34 2FD 0.01208 0.41216 2.97872
56 1P1C SAH 0.000009786 0.51284 3.01508
57 2ZL4 ALA ALA ALA ALA 0.01923 0.41302 3.06122
58 3P2E SAH 0.0002819 0.46148 3.11111
59 5HJM MTA 0.00001605 0.51964 3.15789
60 1KPG SAH 0.00004964 0.48867 3.15789
61 5E9W SAH 0.0007778 0.46973 3.15789
62 4DA6 GA2 0.007817 0.41734 3.16206
63 4UHF BUA 0.006733 0.41657 3.19149
64 3VPB GLU 0.03592 0.40107 3.19149
65 3JWH SAH 0.00003223 0.53643 3.22581
66 1QAN SAH 0.0000005716 0.56925 3.27869
67 5E1M SAH 0.0002534 0.46344 3.3195
68 1BC5 SAH 0.001729 0.42121 3.34572
69 2W5P CL8 0.0258 0.40959 3.3557
70 3T7S SAM 0.00002074 0.52039 3.35821
71 1MZV AMP 0.005739 0.4322 3.40426
72 3FZG SAM 0.003507 0.42965 3.5
73 4N49 SAM 0.00002026 0.50994 3.50877
74 4BLW SAH 0.000005082 0.50429 3.50877
75 1TPY SAH 0.00005015 0.48848 3.50877
76 1U2Z SAH 0.0000872 0.47411 3.50877
77 4BLW AMP 0.000009607 0.45253 3.50877
78 3MBI HSX 0.005573 0.43752 3.50877
79 2JFV FLC 0.01803 0.41953 3.50877
80 3FPF TNA 0.00002415 0.41368 3.50877
81 3FPF MTA 0.00002415 0.41368 3.50877
82 5FTW SAH 0.001508 0.43059 3.51562
83 5XVQ SAH 0.0002838 0.45321 3.52113
84 1NJR XYL 0.0005222 0.42297 3.52113
85 3GCZ SAM 0.000001419 0.5718 3.5461
86 3LCV SAM 0.004277 0.40514 3.55872
87 3EVF SAH 0.00002685 0.42573 3.61011
88 3EVF GTA 0.00003074 0.41156 3.61011
89 1O5O U5P 0.008125 0.42051 3.61991
90 1X87 NAD 0.0002235 0.45744 3.62976
91 5JE0 AZ8 0.0001243 0.42873 3.64372
92 5JE0 SAH 0.0001243 0.42873 3.64372
93 1XTT U5P 0.009697 0.40924 3.7037
94 2O66 FLC 0.03649 0.40072 3.7037
95 1G60 SAM 0.0000006235 0.58064 3.84615
96 3S1S SAH 0.000003855 0.52933 3.85965
97 4DCM SAM 0.00002983 0.52508 3.85965
98 5JGL SAM 0.0001181 0.49217 3.85965
99 5DX8 SFG 0.00004946 0.48415 3.85965
100 5DXA SFG 0.00005047 0.48379 3.85965
101 5DX1 SFG 0.00003363 0.4793 3.85965
102 1V5F FAD 0.003838 0.44025 3.85965
103 4PIO AVI 0.00009845 0.42105 3.85965
104 4PIO SAH 0.0001052 0.41552 3.85965
105 3S5W FAD 0.000896 0.40177 3.85965
106 1I9G SAM 0.00000005444 0.6189 3.92857
107 3H2B SAH 0.00006339 0.49384 3.94089
108 1KYZ SAH 0.001075 0.4447 4.21053
109 1CZA GLC 0.01794 0.41167 4.21053
110 2QES ADE 0.009059 0.43254 4.21456
111 3LE7 ADE 0.01215 0.42415 4.21456
112 2JBH 5GP 0.00899 0.42696 4.44444
113 2PX8 SAH 0.00002064 0.52049 4.46097
114 5CUQ NSC 0.00001209 0.51758 4.49438
115 2EJU SAH 0.0000004863 0.59234 4.5614
116 3LKZ SFG 0.000007734 0.53335 4.5614
117 1Z3C SA8 0.0001975 0.42733 4.5614
118 2Z48 A2G 0.02471 0.4021 4.5614
119 3MQ2 SAH 0.001626 0.4408 4.58716
120 2VT3 ATP 0.004003 0.43538 4.65116
121 4R6W SAH 0.000336 0.40866 4.65116
122 5MGZ SAH 0.00002147 0.51418 4.66102
123 1JG3 ADN 0.000002177 0.5636 4.68085
124 2BZG SAH 0.00006681 0.49796 4.74138
125 2VDV SAM 0.000004913 0.5683 4.87805
126 4I5I 4I5 0.01859 0.40684 4.87805
127 4II2 ATP 0.0007659 0.44307 4.90798
128 2ZIF SAM 0.0000001478 0.60768 4.91228
129 1FP1 SAH 0.0006074 0.46477 4.91228
130 5KJW 53C 0.01537 0.42352 4.91228
131 1JQ3 AAT 0.0001149 0.42292 4.91228
132 3BGD SAH 0.0001635 0.46298 5
133 3BGD PM6 0.0003575 0.428 5
134 2PWY SAH 0.00000006852 0.60069 5.03876
135 3C3Y SAH 0.0001266 0.48086 5.06329
136 3KU0 ADE 0.01124 0.42823 5.17928
137 4DVR 0LY 0.01718 0.40473 5.18868
138 2YX1 SFG 0.0000005075 0.61476 5.26316
139 5THY SAH 0.000003633 0.54158 5.26316
140 5THZ SAH 0.0000112 0.51044 5.26316
141 3LST SAH 0.0003327 0.48202 5.26316
142 5GM1 SAH 0.00007627 0.47648 5.26316
143 1LVL NAD 0.001123 0.43602 5.26316
144 3L9W GSH 0.000222 0.43052 5.26316
145 5MW4 5JU 0.0000603 0.42472 5.26316
146 3L9W AMP 0.0002646 0.41836 5.26316
147 5JE8 NAD 0.002764 0.40533 5.26316
148 1R6D NAD 0.02026 0.40169 5.26316
149 1R6D DAU 0.02072 0.40055 5.26316
150 3KP6 SAL 0.03802 0.40073 5.29801
151 1UAY ADN 0.001601 0.44985 5.3719
152 3U40 ADN 0.01572 0.40296 5.3719
153 3Q87 SAM 0.00007414 0.47698 5.6
154 4KRI SAH 0.00002544 0.50575 5.61404
155 4AZT SAM 0.0001031 0.48964 5.61404
156 1MV8 NAD 0.002828 0.40004 5.61404
157 5XLX SAH 0.01018 0.40151 5.67376
158 1I4D GDP 0.0265 0.40299 5.80357
159 1QB7 ADE 0.01508 0.41137 5.9322
160 5E72 SAM 0.0000000148 0.63519 5.96491
161 3ICT ADP 0.005865 0.42736 5.96491
162 3ICS ADP 0.007716 0.4216 5.96491
163 2CDU ADP 0.009437 0.40629 5.96491
164 2A14 SAH 0.0004564 0.44862 6.08365
165 4LWP SAH 0.0003467 0.46639 6.31579
166 1ZMD NAI 0.001402 0.41667 6.31579
167 5BW4 SAM 0.00001495 0.53264 6.36704
168 3OU2 SAH 0.0001223 0.45741 6.42202
169 5LOG SAH 0.00007976 0.48953 6.43777
170 2DWU DGL 0.02848 0.40138 6.52174
171 3VYW SAM 0.000001081 0.56388 6.66667
172 1L1E SAH 0.0001447 0.47375 6.66667
173 1VBO MAN 0.01068 0.41814 6.71141
174 4NEC SAH 0.0001677 0.49053 6.81818
175 1SQF SAM 0.0000004284 0.59477 7.01754
176 1XDS SAM 0.00009696 0.50726 7.01754
177 1QZZ SAM 0.0002648 0.48669 7.01754
178 4PNE SAH 0.00009157 0.47325 7.01754
179 3H8V ATP 0.002377 0.42946 7.01754
180 1VE3 SAM 0.0002245 0.47473 7.04846
181 2PS1 ORO 0.01023 0.4241 7.07965
182 4M1U A2G MBG 0.01351 0.42454 7.14286
183 5N53 8NB 0.01245 0.42669 7.17949
184 3PQC GDP 0.01525 0.40358 7.17949
185 1V59 NAD 0.0004142 0.48294 7.36842
186 1DJN ADP 0.00518 0.40174 7.36842
187 5XVK SAH 0.0003048 0.45195 7.39437
188 5D4V SAH 0.004655 0.40667 7.46269
189 3A25 SAM 0.00002696 0.51536 7.6412
190 4JLS 3ZE 0.007203 0.43892 7.89474
191 2PXX SAH 0.00007944 0.48961 7.90698
192 4RL4 PPV 0.001352 0.47832 8.01887
193 5G3L SIA 0.01503 0.43229 8.08081
194 3HVJ 705 0.00001782 0.427 8.1448
195 3ACC 5GP 0.02666 0.40286 8.28729
196 3U31 NAD 0.003228 0.41328 8.42105
197 1Q0S SAH 0.00000005412 0.59822 8.49421
198 4XUC 43G 0.00009693 0.41769 8.7156
199 4XUC SAM 0.00009693 0.41769 8.7156
200 5IL1 SAM 0.004949 0.41538 8.77193
201 5K7U SAM 0.007782 0.40668 8.77193
202 5N5D SAM 0.00003947 0.50274 8.84956
203 1ZN7 ADE 0.005597 0.43274 8.88889
204 1ZN7 HSX 0.005597 0.43274 8.88889
205 3A27 SAM 0.000003691 0.55348 9.12281
206 4A6D SAM 0.0008752 0.44453 9.12281
207 4EIP FAD 0.01232 0.40498 9.12281
208 4EIP K2C 0.01401 0.40422 9.12281
209 3BXO SAM 0.00002186 0.53775 9.20502
210 2HNK SAH 0.00006229 0.48927 9.20502
211 1LSS NAD 0.0001118 0.4785 9.28571
212 3PT9 SAH 0.00000007012 0.62947 9.47368
213 3HQP FDP 0.01708 0.40868 9.47368
214 4XFR CIT 0.03417 0.4039 9.47368
215 5GWX SAM 0.0005625 0.42612 9.50704
216 5GWX SAR 0.0005625 0.42612 9.50704
217 1DQN IMU 0.009544 0.42564 9.56522
218 1VKF CIT 0.02827 0.41144 9.57447
219 4YMH SAH 0.00002618 0.50522 9.58333
220 1DL5 SAH 0.000002716 0.51441 9.82456
221 3QOX SAH 0.00001305 0.50775 9.82456
222 1L3I SAH 0.0000002681 0.55095 9.89583
223 4DZ1 DAL 0.03751 0.40058 10.0386
224 5DNK SAH 0.000297 0.4958 10.1754
225 1KPH SAH 0.00004873 0.489 10.1754
226 3GWZ SAH 0.0006026 0.46986 10.1754
227 3GXO SAH 0.001546 0.44606 10.1754
228 4IF4 BEF 0.01127 0.42166 10.5769
229 1I1N SAH 0.000003556 0.5014 10.6195
230 2FKA BEF 0.01434 0.40685 10.8527
231 2HMT NAI 0.001573 0.42627 11.1111
232 4AZW SAM 0.0001153 0.48261 11.2281
233 5E8J SAH 0.0004967 0.47382 11.3636
234 1L5Y BEF 0.02527 0.40145 11.6129
235 1PZM 5GP 0.01333 0.41824 11.8483
236 1ZGA SAH 0.0005633 0.47124 11.9298
237 3BJE R1P 0.0258 0.40358 11.9298
238 5MPT SAH 0.00001497 0.52663 12.0773
239 3R51 MMA 0.0163 0.42274 12.5
240 3MB5 SAM 0.0000002207 0.57999 12.549
241 4KCT FDP 0.01461 0.40815 12.6316
242 3WV8 ATP 0.0001473 0.47801 12.844
243 3ELW SAM 0.0000297 0.40481 12.9825
244 4POO SAM 0.000000001442 0.66121 13.5
245 1R18 SAH 0.0000009683 0.55973 13.6564
246 2YVJ NAI 0.004038 0.41929 13.6842
247 5ULP KB1 0.000006988 0.51375 13.806
248 4C2G ALA ALA ALA ALA 0.02356 0.4056 14.0351
249 5FA8 SAM 0.000001496 0.5461 14.9068
250 4DMG SAM 0.000009547 0.56191 15.0877
251 1O94 ADP 0.004241 0.40236 15.0877
252 3G2O SAM 0.000003437 0.55485 15.7895
253 3DXY SAM 0.00002109 0.54531 16.055
254 4GQB 0XU 0.000006652 0.51461 18.1818
255 4OBW SAM 0.0002726 0.471 19.0661
256 5FA5 MTA 0.000009176 0.54868 20
257 5GVR LMR 0.0094 0.46298 21.3675
258 1XTP SAI 0.00006187 0.49944 22.8346
259 2ZFU SAH 0.000439 0.45332 28.8372
260 5DWQ SFG 0.00002768 0.48984 35
261 5DX0 SFG 0.00003965 0.47657 35
262 5L95 AMP 0.00167 0.43239 38.75
Pocket No.: 2; Query (leader) PDB : 1WG8; Ligand: SAM; Similar sites found: 37
This union binding pocket(no: 2) in the query (biounit: 1wg8.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1SQL GUN 0.01659 0.41559 1.36986
2 5DT6 GLU 0.008512 0.4318 1.49813
3 1VHW ADN 0.004578 0.43377 1.58103
4 3W68 PBU 0.01628 0.4192 2.25564
5 2DUR MAN MAN 0.01461 0.41615 2.37154
6 2PHR MAN MAN 0.02162 0.40876 2.38095
7 2PHW MAN MAN 0.02201 0.40835 2.38095
8 2PHF MAN MAN 0.02338 0.40698 2.38095
9 1Q8P MAN MMA 0.02568 0.40485 2.38095
10 2GND MAN MMA 0.02632 0.4043 2.38095
11 2GMM MAN MAN 0.02163 0.4027 2.38095
12 5T52 A2G 0.01546 0.41192 2.89256
13 1QH9 LAC 0.02636 0.40936 3.01724
14 2RBK VN4 0.02946 0.40196 3.06513
15 2J5V PCA 0.02826 0.411 3.15789
16 5MX4 HPA 0.03314 0.40109 3.86266
17 3I6B KDO 0.02984 0.40144 3.88889
18 2PZE ATP 0.04337 0.40123 3.93013
19 5F7J ADE 0.004558 0.41021 4.21053
20 3KB6 LAC 0.03405 0.40279 4.21053
21 3CT5 NAG NAG NAG 0.03161 0.40014 4.40252
22 2Z49 AMG 0.008124 0.42076 4.5614
23 2Z48 NGA 0.011 0.4157 4.5614
24 1RZM E4P 0.01019 0.43119 4.91228
25 1V8K ANP 0.01083 0.4154 5.26316
26 1C1X HFA 0.01208 0.40906 5.61404
27 3QPB URA 0.03199 0.40193 6.02837
28 1YXM ADE 0.01671 0.41488 7.01754
29 4OJP MAL 0.03049 0.40451 7.36842
30 5EEL MLA 0.02891 0.41041 7.5
31 1K27 MTM 0.00535 0.40723 8.12721
32 2A8Y MTA 0.006429 0.4038 9.62963
33 3FGZ BEF 0.002814 0.4475 10.1562
34 2PYY GLU 0.02143 0.40473 14.0351
35 4L6T GAL NGA GAL BGC SIA 0.02544 0.40095 14.2857
36 1PEA ACM 0.02349 0.41256 15.0877
37 4NTX AMR 0.01572 0.42343 21.0084
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