Receptor
PDB id Resolution Class Description Source Keywords
1WAP 1.8 Å NON-ENZYME: TRANSCRIPT_TRANSLATE TRP RNA-BINDING ATTENUATION PROTEIN IN COMPLEX WITH L-TRYPTO BACILLUS SUBTILIS TRP OPERON BACILLUS SUBTILIS RNA-BINDING ATTENUATION PROTE
Ref.: THE STRUCTURE OF TRP RNA-BINDING ATTENUATION PROTEI NATURE V. 374 693 1995
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
TRP A:81;
B:81;
C:81;
D:81;
E:81;
F:81;
G:81;
H:81;
I:81;
J:81;
K:81;
L:81;
M:81;
N:81;
O:81;
P:81;
Q:81;
R:81;
S:81;
T:81;
U:81;
V:81;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
204.225 C11 H12 N2 O2 c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1WAP 1.8 Å NON-ENZYME: TRANSCRIPT_TRANSLATE TRP RNA-BINDING ATTENUATION PROTEIN IN COMPLEX WITH L-TRYPTO BACILLUS SUBTILIS TRP OPERON BACILLUS SUBTILIS RNA-BINDING ATTENUATION PROTE
Ref.: THE STRUCTURE OF TRP RNA-BINDING ATTENUATION PROTEI NATURE V. 374 693 1995
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 1WAP - TRP C11 H12 N2 O2 c1ccc2c(c1....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 2ZD0 - TRP C11 H12 N2 O2 c1ccc2c(c1....
2 2ZCZ - TRP C11 H12 N2 O2 c1ccc2c(c1....
3 2EXT - TRP C11 H12 N2 O2 c1ccc2c(c1....
4 1QAW Kd = 7.5 uM TRP C11 H12 N2 O2 c1ccc2c(c1....
5 2EXS - TRP C11 H12 N2 O2 c1ccc2c(c1....
6 3ZZL - TRP C11 H12 N2 O2 c1ccc2c(c1....
7 3ZZS - TRP C11 H12 N2 O2 c1ccc2c(c1....
8 1WAP - TRP C11 H12 N2 O2 c1ccc2c(c1....
9 3ZZQ - TRP C11 H12 N2 O2 c1ccc2c(c1....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 2ZD0 - TRP C11 H12 N2 O2 c1ccc2c(c1....
2 2ZCZ - TRP C11 H12 N2 O2 c1ccc2c(c1....
3 2EXT - TRP C11 H12 N2 O2 c1ccc2c(c1....
4 1QAW Kd = 7.5 uM TRP C11 H12 N2 O2 c1ccc2c(c1....
5 2EXS - TRP C11 H12 N2 O2 c1ccc2c(c1....
6 3ZZL - TRP C11 H12 N2 O2 c1ccc2c(c1....
7 3ZZS - TRP C11 H12 N2 O2 c1ccc2c(c1....
8 1WAP - TRP C11 H12 N2 O2 c1ccc2c(c1....
9 3ZZQ - TRP C11 H12 N2 O2 c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: TRP; Similar ligands found: 31
No: Ligand ECFP6 Tc MDL keys Tc
1 TRP 1 1
2 DTR 1 1
3 LTN 0.765957 0.777778
4 3IL 0.666667 0.75
5 4Z9 0.666667 0.75
6 TR7 0.666667 0.833333
7 FT6 0.561404 0.888889
8 IAC 0.538462 0.787879
9 TSR 0.529412 0.722222
10 IOP 0.518519 0.764706
11 R59 0.515152 0.72093
12 R38 0.515152 0.72093
13 3IB 0.491228 0.742857
14 ITW 0.491228 0.694444
15 IAD 0.484375 0.738095
16 TRP GLY 0.484375 0.636364
17 TSS 0.471698 0.666667
18 CTE 0.467742 0.888889
19 DTE 0.467742 0.888889
20 IAV 0.461538 0.738095
21 IAG 0.459016 0.738095
22 LYS TRP 0.43662 0.644444
23 78U 0.42623 0.794118
24 TRP LEU PHE VAL GLN ARG ASP SER LYS GLU 0.424658 0.627907
25 0ZN 0.421687 0.673913
26 4OG 0.416667 0.8
27 ASP TRP ASN 0.415584 0.673913
28 GLU ASP ASN ASP TRP ASN 0.415584 0.673913
29 LSW 0.411765 0.680851
30 X95 0.411765 0.680851
31 LYS TRP LYS 0.402597 0.638298
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: 33
This union binding pocket(no: 1) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4BVA T3 0.005283 0.44193 None
2 2E1A MSE 0.003268 0.43384 None
3 1GS5 NLG 0.01437 0.41508 None
4 3KA2 2NC 0.02954 0.41301 None
5 1WUB OTP 0.03303 0.40493 None
6 4I53 1C1 0.01052 0.40471 None
7 3AB1 FAD 0.03908 0.40036 None
8 4I54 1C1 0.02291 0.40171 2.66667
9 3LZW FAD 0.02641 0.40713 4
10 3LXK MI1 0.01661 0.40463 4
11 5D9G GLU ASN LEU TYR PHE GLN 0.01584 0.40044 5.33333
12 5EW9 5VC 0.01292 0.45488 6.66667
13 3F8D FAD 0.04811 0.41359 8
14 1FFU CDP 0.02223 0.41088 8
15 4B2Z P5S 0.03343 0.40105 8
16 5IXJ THR 0.01756 0.40733 9.33333
17 2J3M ATP 0.01117 0.40688 9.33333
18 1RM0 NAI 0.03717 0.40559 9.33333
19 2Q4W FAD 0.02401 0.4052 9.33333
20 1V0O INR 0.007172 0.41056 10.6667
21 5VIT MLI 0.008927 0.42646 12
22 2RCU BUJ 0.02791 0.41646 12
23 1JIL 485 0.01115 0.40352 12
24 1DZK PRZ 0.004136 0.40793 13.3333
25 2GKS ADP 0.01057 0.40634 14.6667
26 3THR C2F 0.008253 0.40378 14.6667
27 1FL2 FAD 0.03181 0.40399 16
28 1T3Q MCN 0.0193 0.41094 17.3333
29 4D9C PMP 0.01745 0.40081 17.3333
30 3CTY FAD 0.01954 0.41904 22.6667
31 2WPF WPF 0.03645 0.43015 32
32 2WPF FAD 0.04394 0.42445 32
33 1RM6 PCD 0.02117 0.41381 37.3333
Pocket No.: 2; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 1wap.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 1wap.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 1wap.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 13; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 13) in the query (biounit: 1wap.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 14; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 14) in the query (biounit: 1wap.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 15; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: 21
This union binding pocket(no: 15) in the query (biounit: 1wap.bio2) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3FSJ D7K 0.01343 0.41186 None
2 4YEE 4CQ 0.02406 0.40041 None
3 5N87 N66 0.02336 0.40252 4
4 5UIU 8CG 0.01154 0.4113 8
5 3ZJX BOG 0.01887 0.40336 8
6 2YAK OSV 0.01116 0.41197 9.33333
7 4K49 HFQ 0.01923 0.4066 9.33333
8 1X7D ORN 0.02265 0.40622 9.33333
9 5HVJ ANP 0.01456 0.41332 10.6667
10 1XV5 UDP 0.008025 0.40057 10.6667
11 2UUU FAD 0.01265 0.43139 12
12 2UUU PL3 0.01265 0.43139 12
13 3IAE D7K 0.01493 0.40848 12
14 5JAQ NAI 0.0258 0.40535 13.3333
15 3FB4 AP5 0.02617 0.40411 14.6667
16 5G41 AP5 0.02945 0.40599 16
17 3EYA TDP 0.01326 0.4044 17.3333
18 5MY8 RXZ 0.01159 0.40566 18.6667
19 2JLD AG1 0.02297 0.40069 21.3333
20 4L2I NAD 0.01625 0.41968 25.3333
21 4L2I FAD 0.01152 0.41841 25.3333
Pocket No.: 16; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 16) in the query (biounit: 1wap.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 17; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 17) in the query (biounit: 1wap.bio2) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 18; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 18) in the query (biounit: 1wap.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 19; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 19) in the query (biounit: 1wap.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 20; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 20) in the query (biounit: 1wap.bio2) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 21; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 21) in the query (biounit: 1wap.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 22; Query (leader) PDB : 1WAP; Ligand: TRP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 22) in the query (biounit: 1wap.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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