Receptor
PDB id Resolution Class Description Source Keywords
1VQW 2.4 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF A PROTEIN WITH SIMILARITY TO FLAVIN- CONTAINING MONOOXYGENASES AND TO MAMMALIAN DIMETHYLALANINE M ONOOXYGENASES SCHIZOSACCHAROMYCES POMBE DIMER FLAVIN-CONTAINING NYSGXRC PROTEIN STRUCTURE INITIATIVE PSI T1729 STRUCTURAL GENOMICS NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS UNKNOWN FUNCTION
Ref.: MECHANISM OF ACTION OF A FLAVIN-CONTAINING MONOOXYGENASE. PROC.NATL.ACAD.SCI.USA V. 103 9832 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EPE A:502;
A:503;
Invalid;
Invalid;
none;
none;
submit data
238.305 C8 H18 N2 O4 S C1CN(...
FAD A:500;
B:501;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1VQW 2.4 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF A PROTEIN WITH SIMILARITY TO FLAVIN- CONTAINING MONOOXYGENASES AND TO MAMMALIAN DIMETHYLALANINE M ONOOXYGENASES SCHIZOSACCHAROMYCES POMBE DIMER FLAVIN-CONTAINING NYSGXRC PROTEIN STRUCTURE INITIATIVE PSI T1729 STRUCTURAL GENOMICS NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS UNKNOWN FUNCTION
Ref.: MECHANISM OF ACTION OF A FLAVIN-CONTAINING MONOOXYGENASE. PROC.NATL.ACAD.SCI.USA V. 103 9832 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 1VQW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 1VQW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 1VQW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 DAL FAD PER 0.772414 0.951807
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 62F 0.572327 0.939024
12 F2N 0.566265 0.886364
13 FMN 0.543307 0.876543
14 FA9 0.526316 0.939759
15 6YU 0.516304 0.860215
16 CNV FAD 0.511905 0.908046
17 P6G FDA 0.511628 0.908046
18 FAD NBT 0.508876 0.83871
19 A2D 0.504065 0.875
20 P5F 0.491329 0.941176
21 FAD CNX 0.488506 0.8125
22 APR 0.488372 0.851852
23 AR6 0.488372 0.851852
24 AGS 0.484615 0.811765
25 SAP 0.484615 0.811765
26 M33 0.484375 0.864198
27 BA3 0.484127 0.875
28 FAD NBA 0.480663 0.802083
29 ATP 0.48062 0.851852
30 B4P 0.480315 0.875
31 ADP 0.480315 0.851852
32 AP5 0.480315 0.875
33 ANP 0.477273 0.831325
34 AQP 0.476923 0.851852
35 5FA 0.476923 0.851852
36 48N 0.469388 0.902439
37 OAD 0.467626 0.876543
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AD9 0.462121 0.831325
41 3OD 0.460993 0.876543
42 RBF 0.460938 0.790123
43 FB0 0.460606 0.835165
44 139 0.460526 0.858824
45 AP0 0.46 0.835294
46 A22 0.459854 0.864198
47 ACP 0.458015 0.853659
48 8QN 0.456522 0.864198
49 PRX 0.454545 0.831325
50 A1R 0.453237 0.86747
51 G3A 0.452055 0.902439
52 T5A 0.45098 0.872093
53 G5P 0.44898 0.902439
54 ATF 0.448529 0.821429
55 50T 0.44697 0.819277
56 ACQ 0.444444 0.853659
57 PAJ 0.442857 0.847059
58 ADQ 0.442857 0.853659
59 5AL 0.441176 0.864198
60 ADX 0.439394 0.775281
61 CA0 0.439394 0.853659
62 A4P 0.437909 0.831461
63 25L 0.4375 0.864198
64 P33 FDA 0.436464 0.817204
65 5SV 0.435714 0.793103
66 TXE 0.434211 0.890244
67 OMR 0.434211 0.818182
68 ABM 0.434109 0.829268
69 A 0.433071 0.82716
70 AMP 0.433071 0.82716
71 4AD 0.432624 0.855422
72 ADJ 0.432258 0.818182
73 BIS 0.430556 0.802326
74 SRA 0.429688 0.788235
75 AFH 0.42953 0.825581
76 TXD 0.427632 0.890244
77 NXX 0.427632 0.865854
78 UP5 0.427632 0.878049
79 DND 0.427632 0.865854
80 6V0 0.427632 0.857143
81 SRP 0.42446 0.843373
82 PR8 0.423611 0.837209
83 TAT 0.423358 0.821429
84 AMO 0.422535 0.865854
85 PTJ 0.42069 0.835294
86 FYA 0.42069 0.864198
87 TXA 0.42069 0.865854
88 CNA 0.420382 0.865854
89 00A 0.41958 0.823529
90 AHX 0.41958 0.835294
91 MAP 0.41844 0.811765
92 NAI 0.418301 0.845238
93 AU1 0.41791 0.831325
94 AP2 0.416667 0.843373
95 A12 0.416667 0.843373
96 25A 0.415493 0.851852
97 AMP MG 0.415385 0.785714
98 COD 0.415094 0.842697
99 ADP BEF 0.414815 0.77907
100 BEF ADP 0.414815 0.77907
101 4TC 0.412903 0.879518
102 APC 0.411765 0.843373
103 NB8 0.410959 0.835294
104 ME8 0.410959 0.806818
105 1ZZ 0.410959 0.806818
106 4UW 0.409091 0.825581
107 NAX 0.409091 0.837209
108 RBY 0.408759 0.843373
109 ADV 0.408759 0.843373
110 ADP MG 0.407407 0.797619
111 P1H 0.405882 0.818182
112 OOB 0.405594 0.864198
113 A A 0.40411 0.829268
114 LAD 0.40411 0.825581
115 UPA 0.403846 0.86747
116 4UU 0.401316 0.833333
117 A3D 0.401235 0.876543
118 DLL 0.4 0.864198
119 XAH 0.4 0.806818
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1VQW; Ligand: FAD; Similar sites found: 575
This union binding pocket(no: 1) in the query (biounit: 1vqw.bio1) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3GD4 NAD 0.000001412 0.56507 0.656455
2 3GD4 FAD 0.0000007452 0.56251 0.656455
3 2GSD NAD 0.001742 0.40993 0.995025
4 1U8X NAD 0.005894 0.40215 1.09409
5 2RGJ FAD 0.0000001651 0.55378 1.24378
6 2O4C NAD 0.0005247 0.41942 1.31579
7 1E3I CXF 0.0008365 0.40573 1.32979
8 2FZW NAD 0.00118 0.42509 1.34048
9 3H9E NAD 0.0001152 0.47077 1.44509
10 3CMC NAD 0.0023 0.43017 1.49701
11 3BAZ NAP 0.001008 0.43613 1.5015
12 2NAD NAD 0.001807 0.40935 1.52672
13 2RGH FAD 0.000001668 0.52865 1.53173
14 2ZXI FAD 0.000001945 0.49075 1.53173
15 1X87 NAD 0.00004164 0.43123 1.53173
16 2IXB NAD 0.00103 0.42101 1.57658
17 2IXB A2G 0.0008427 0.40064 1.57658
18 1U3U BNF 0.0023 0.41312 1.60428
19 1SB8 UD2 0.0006516 0.44254 1.70455
20 1SB8 NAD 0.0005223 0.44254 1.70455
21 2YVF NAD 0.000002395 0.54564 1.71569
22 2YVF FAD 0.000002262 0.54561 1.71569
23 2CUL FAD 0.000001024 0.51147 1.72414
24 3JV7 NAD 0.0007179 0.42975 1.73913
25 1KPG SAH 0.005632 0.41412 1.74216
26 3S5W FAD 0.00000000716 0.59216 1.75055
27 3CGD FAD 0.0000005659 0.58383 1.75055
28 3CGD COA 0.0000005659 0.58383 1.75055
29 3CGD NAD 0.0000005659 0.58383 1.75055
30 3CGB FAD 0.0000000582 0.54094 1.75055
31 5UAO FAD 0.000005873 0.5053 1.75055
32 4Z24 FAD 0.000001054 0.47319 1.75055
33 1Z45 NAD 0.0003868 0.44 1.75055
34 5JJR SAH 0.002523 0.43977 1.75055
35 3S5W NAP 0.00002352 0.40095 1.75055
36 1GET NAP 0.000000147 0.60007 1.77778
37 1GET FAD 0.0000001306 0.60007 1.77778
38 3V1Y NAD 0.00003794 0.49013 1.78042
39 3AXB FAD 0.0000001383 0.52742 1.78571
40 3AXB PRO 0.000000228 0.49191 1.78571
41 1WDK NAD 0.00003158 0.4308 1.79487
42 4ZGS NAD 0.0003682 0.40218 1.81347
43 5GZ6 NDP 0.0001957 0.48135 1.84049
44 5GZ6 7C3 0.000372 0.46115 1.84049
45 2VHW NAI 0.00007394 0.46171 1.85676
46 1OMO NAD 0.00006308 0.42642 1.86335
47 1SQF SAM 0.00399 0.43066 1.8648
48 1GR0 NAD 0.0004757 0.42931 1.90736
49 5AYV KPL 0.0007629 0.4231 1.94175
50 5AYV NAP 0.0001686 0.40977 1.94175
51 4MIG G3F 0.0000002397 0.57194 1.96937
52 3QVP FAD 0.0000008047 0.54494 1.96937
53 4HA6 FAD 0.000000474 0.47873 1.96937
54 4RPL FAD 0.000003229 0.54244 2.00501
55 4RPL 3UC 0.000004372 0.53997 2.00501
56 3HDY FDA 0.000003085 0.40418 2.01511
57 3HDY FAD 0.000005186 0.40165 2.01511
58 3HDY GDU 0.000005906 0.40081 2.01511
59 3U31 NAD 0.009596 0.40411 2.06897
60 4XDY NAI 0.002122 0.41999 2.07101
61 1DXY NAD 0.00003202 0.44393 2.1021
62 2JJQ SAH 0.001642 0.46107 2.11765
63 1XCL SAH 0.001279 0.41486 2.12766
64 3LAD FAD 0.0000000577 0.58667 2.18818
65 4BV6 FAD 0.000000182 0.56628 2.18818
66 4YNU FAD 0.0000007851 0.54676 2.18818
67 4YNU LGC 0.000001087 0.54667 2.18818
68 4M52 FAD 0.00000002454 0.52179 2.18818
69 2A8X FAD 0.00000005275 0.50606 2.18818
70 5FA5 MTA 0.0005222 0.48029 2.18818
71 3S1S SAH 0.002757 0.42432 2.18818
72 5U8U FAD 0.0000001411 0.42426 2.18818
73 1QMG APX 0.007675 0.40546 2.18818
74 5BVA FAD 0.0000001691 0.48446 2.20049
75 3WMX NAD 0.001096 0.43151 2.23464
76 4K5S FAD 0.00000002986 0.58078 2.23881
77 4K5S PM0 0.0000001411 0.4676 2.23881
78 4NEC SAH 0.007167 0.42605 2.27273
79 1R37 NAD 0.001177 0.41493 2.30548
80 1YJQ NAP 0.0005155 0.42668 2.31023
81 1ELI PYC 0.00001097 0.49521 2.31362
82 4JJF FE9 0.001195 0.427 2.32558
83 2AF6 BRU 0.03077 0.41631 2.32558
84 4JJF N2I 0.002154 0.41153 2.32558
85 4D7E FAD 0.000000285 0.52611 2.331
86 4KOA NDP 0.001389 0.45573 2.4024
87 5M67 3D1 0.0001838 0.46095 2.407
88 5M67 ADE 0.0002154 0.4583 2.407
89 5M67 NAD 0.0002304 0.45718 2.407
90 4RDH AMP 0.00002634 0.54208 2.43056
91 4RDI ATP 0.00004881 0.40905 2.43056
92 3H4V DVP 0.004987 0.40042 2.43056
93 1C3V NDP 0.001908 0.41095 2.44898
94 4YMH SAH 0.0008451 0.45344 2.5
95 4CJX NAP 0.004282 0.41046 2.50784
96 2F1K NAP 0.00003756 0.4903 2.50896
97 1P1C SAH 0.00003546 0.43078 2.51256
98 3WGT FAD 0.0000003333 0.56509 2.59366
99 3WGT QSC 0.0000003611 0.56509 2.59366
100 3NYC FAD 0.0000004894 0.44757 2.62467
101 3NYC IAR 0.0000004894 0.44757 2.62467
102 3ICR FAD 0.000000109 0.56787 2.62582
103 3ICT FAD 0.0000001108 0.5676 2.62582
104 3ICS FAD 0.0000001266 0.56722 2.62582
105 1BZL FAD 0.000005199 0.55456 2.62582
106 3ICT ADP 0.00000002053 0.46396 2.62582
107 3ICS ADP 0.00000003493 0.46007 2.62582
108 1V8B NAD 0.0001138 0.45481 2.62582
109 3AYI FAD 0.0000004773 0.44749 2.62582
110 3AYI HCI 0.000000508 0.44349 2.62582
111 1OBB NAD 0.006089 0.40691 2.62582
112 3GMB FAD 0.0000004286 0.54057 2.6506
113 3B1J NAD 0.0002173 0.44955 2.65487
114 3B20 NAD 0.0003791 0.4044 2.65487
115 2EV9 SKM 0.0006106 0.42673 2.6616
116 2EV9 NAP 0.0006106 0.42033 2.6616
117 4RQU NAD 0.00019 0.42649 2.66667
118 1CF2 NAP 0.00002368 0.45151 2.67062
119 4L8V NAP 0.001183 0.40383 2.67062
120 1DSS NAD 0.00001548 0.45123 2.7027
121 1X14 NAD 0.000005888 0.42445 2.74314
122 1J5P NAD 0.00008667 0.47196 2.7668
123 3KU0 ADE 0.04881 0.40242 2.78884
124 1LTH NAD 0.00005328 0.42965 2.82132
125 1YKF NAP 0.004136 0.4007 2.84091
126 2HQM FAD 0.00000005594 0.58718 2.84464
127 1DJN ADP 0.000000002064 0.56254 2.84464
128 2WPF WPF 0.000003877 0.56121 2.84464
129 2WPF FAD 0.00000355 0.56081 2.84464
130 4C3Y FAD 0.00000378 0.51677 2.84464
131 4C3Y ANB 0.000007162 0.51279 2.84464
132 5BR7 FAD 0.000002611 0.40581 2.84464
133 4U8P FDA 0.00000085 0.40346 2.84464
134 5BR7 FLC 0.000003876 0.40087 2.84464
135 1X7D ORN 0.0009493 0.42205 2.85714
136 1X7D NAD 0.0003321 0.41975 2.85714
137 3SSO SAH 0.0001571 0.40121 2.86396
138 1NVM NAD 0.0007767 0.42561 2.88462
139 5KKA 6V0 0.001551 0.41176 2.88462
140 2D2I NAP 0.000391 0.4031 2.89474
141 4M38 SAH 0.0002015 0.48079 2.91545
142 1RM4 NDP 0.0002789 0.41881 2.96736
143 1XHC FAD 0.00000003182 0.58577 2.99728
144 2CDC XYP 0.002966 0.42508 3.00546
145 2CDC XYS 0.004215 0.41898 3.00546
146 2CDC NAP 0.004215 0.41898 3.00546
147 3ABI NAD 0.0002106 0.45007 3.0137
148 3SQP FAD 0.000001863 0.60007 3.06346
149 1QO8 FAD 0.00000003337 0.59564 3.06346
150 1N4W FAD 0.000006786 0.50989 3.06346
151 5JWC FAD 0.000001982 0.50228 3.06346
152 1PN0 FAD 0.000000787 0.45666 3.06346
153 1PN0 IPH 0.0000008504 0.45185 3.06346
154 2R4J 13P 0.000001063 0.43579 3.06346
155 2R4J FAD 0.000001063 0.43579 3.06346
156 2FK8 SAM 0.005106 0.41908 3.06346
157 1NPD NAD 0.002362 0.42403 3.125
158 3NTA FAD 0.0000002424 0.51469 3.13589
159 4FN4 NAD 0.003553 0.40322 3.14961
160 3ZNN 4WL 0.0000004946 0.56838 3.17003
161 3ZNN FAD 0.0000004946 0.56838 3.17003
162 1YQZ FAD 0.0000003587 0.42829 3.19635
163 2VDV SAM 0.0006167 0.48178 3.25203
164 1R6D NAD 0.0005851 0.44524 3.2641
165 1R6D DAU 0.0005774 0.44458 3.2641
166 4FWE FAD 0.00000008629 0.58165 3.26633
167 2HK9 NAP 0.0005328 0.40393 3.27273
168 2VVM FAD 0.0000002559 0.55914 3.28228
169 2DKH 3HB 0.0000003164 0.55408 3.28228
170 2DKH FAD 0.0000001908 0.55149 3.28228
171 5WGR FAD 0.000000281 0.49951 3.28228
172 2VVL FAD 0.0000002676 0.49825 3.28228
173 3WE0 FAD 0.0000008251 0.47288 3.28228
174 1U1I NAD 0.0005079 0.42827 3.28228
175 3A4T SFG 0.000703 0.45312 3.28467
176 1C0I BE2 0.02261 0.40376 3.30579
177 1C0I FAD 0.02261 0.40376 3.30579
178 1KEW NAD 0.0006941 0.44059 3.3241
179 1KEW TYD 0.001348 0.42855 3.3241
180 2WET FAD 0.0000005141 0.54934 3.32681
181 3AB1 FAD 0.000000004158 0.5572 3.33333
182 3CIF NAD 0.00007318 0.44231 3.34262
183 3CIF G3H 0.0008025 0.42229 3.34262
184 4GUT FAD 0.00000008715 0.58599 3.35052
185 4HSU FAD 0.00000007952 0.58453 3.35052
186 4GUS FAD 0.00000005981 0.50199 3.35052
187 1BXK NAD 0.0002369 0.42601 3.38028
188 3GFB NAD 0.0002372 0.45471 3.42857
189 5I39 FAD 0.0000002696 0.51232 3.43137
190 3NJ4 NAD 0.001809 0.45546 3.44828
191 3NJ4 AFX 0.004698 0.43769 3.44828
192 5X62 SAH 0.004353 0.43257 3.44828
193 2PWY SAH 0.0001693 0.41116 3.48837
194 4XDZ NDP 0.001615 0.42777 3.49854
195 1MO9 FAD 0.0000001219 0.61196 3.50109
196 1MO9 KPC 0.000000135 0.61104 3.50109
197 5J60 FAD 0.00000007571 0.51881 3.50109
198 4OBW SAM 0.004909 0.42653 3.50195
199 2C7G ODP 0.0000003469 0.57206 3.50877
200 2C7G FAD 0.0000003756 0.5719 3.50877
201 1ZQ9 SAM 0.0001511 0.49564 3.50877
202 2YY7 NAD 0.0009683 0.41138 3.52564
203 3MB5 SAM 0.000169 0.47565 3.52941
204 4OPC PGT 0.000002844 0.57071 3.53201
205 4OPC FDA 0.000002219 0.57071 3.53201
206 3NTD FAD 0.0000002217 0.55817 3.53982
207 1EQ2 NAP 0.002594 0.41104 3.54839
208 4PU6 ASP 0.03553 0.41002 3.5533
209 4GLL NAD 0.001272 0.40945 3.56083
210 4X9M FAD 0.0000001683 0.50751 3.58852
211 1BW9 NAD 0.00005396 0.50119 3.65169
212 1BXG NAD 0.0001142 0.42739 3.65169
213 1C1X NAD 0.00006865 0.47979 3.66197
214 2YVJ NAI 0.0000001449 0.63355 3.66972
215 2YVJ FAD 0.0000003559 0.51468 3.66972
216 1ZBQ NAD 0.00272 0.40274 3.66972
217 4JGT PYR 0.04302 0.40695 3.67893
218 3K7M FAD 0.0000005183 0.44265 3.7123
219 1JQ3 AAT 0.002362 0.40262 3.71622
220 3NKS FAD 0.000000156 0.52689 3.71991
221 5TTJ FAD 0.0000001488 0.51618 3.71991
222 4AT0 FAD 0.00001161 0.50595 3.71991
223 5E4R NAP 0.002216 0.41369 3.71991
224 5U5G NAP 0.0008152 0.43055 3.72881
225 3LST SAH 0.02766 0.40447 3.73563
226 2DFV NAD 0.0001315 0.42914 3.7464
227 1E5Q NDP 0.003435 0.4063 3.77778
228 2QA1 FAD 0.00000004041 0.55982 3.8
229 1D4O NAP 0.005824 0.40236 3.80435
230 1D4D FAD 0.00000004599 0.59199 3.84615
231 1JJ7 ADP 0.01496 0.43531 3.84615
232 3LXD FAD 0.0000002444 0.55134 3.85542
233 1L5Y BEF 0.01211 0.40168 3.87097
234 1G6H ADP 0.04594 0.40743 3.89105
235 1EBF NAD 0.0002887 0.40762 3.91061
236 1PL6 572 0.0004161 0.42632 3.93258
237 1PL6 NAD 0.00002267 0.42254 3.93258
238 3WBF NAP 0.0007459 0.43204 3.93443
239 3WBF API 0.001862 0.40638 3.93443
240 2WSB NAD 0.004258 0.40104 3.93701
241 1LVL NAD 0.0000001517 0.618 3.93873
242 2RAB NAD 0.0000002861 0.58644 3.93873
243 2RAB FAD 0.0000000967 0.58131 3.93873
244 1LVL FAD 0.000000196 0.48932 3.93873
245 4MOP 2H5 0.0000001532 0.4603 3.93873
246 1GQ2 NAP 0.0004431 0.44082 3.93873
247 2BH9 NAP 0.009146 0.42099 3.93873
248 3ETG GLU 0.008312 0.40032 3.93873
249 4E5N NAD 0.0003674 0.42528 3.93939
250 2CVQ NDP 0.00198 0.41559 3.97554
251 3TLJ SAH 0.008231 0.40417 4.02145
252 1GY8 NAD 0.0005491 0.41859 4.03023
253 4REP FAD 0.00000006764 0.52671 4.0404
254 3GRU AMP 0.00006344 0.4208 4.0678
255 3QJ4 FAD 0.00000006421 0.53434 4.09357
256 1IM8 SAI 0.002533 0.43248 4.09836
257 3T31 FAD 0.0000008062 0.55777 4.11899
258 3T31 DCQ 0.0000009218 0.55777 4.11899
259 3GDH SAH 0.001969 0.42732 4.14938
260 4TXI FAD 0.00000009498 0.56743 4.15755
261 5VN0 FAD 0.00000009749 0.5274 4.15755
262 1J0X NAD 0.000147 0.45933 4.15755
263 5VN0 NAI 0.000001833 0.41151 4.15755
264 1GAD NAD 0.0004418 0.40822 4.15755
265 4EDF UPG 0.005038 0.40475 4.15755
266 4XB2 NDP 0.00007399 0.41983 4.1791
267 4XB2 HSE 0.0006397 0.41983 4.1791
268 2VYN NAD 0.00005557 0.44598 4.19162
269 3DMH SAM 0.00177 0.43932 4.19948
270 3DMH GMP 0.003163 0.41031 4.19948
271 3C6K MTA 0.002628 0.40454 4.19948
272 3C6K SPD 0.002628 0.40454 4.19948
273 2Q1S NAI 0.00007381 0.47066 4.24403
274 5JE8 NAD 0.0001745 0.46724 4.30464
275 1W73 NAP 0.002187 0.42542 4.30464
276 5H81 NAP 0.0007637 0.45157 4.37018
277 1REO FAD 0.00000001745 0.60103 4.37637
278 1H82 GZZ 0.0000001714 0.59104 4.37637
279 2E5V FAD 0.0000003892 0.55689 4.37637
280 3E1T FAD 0.0000002105 0.48721 4.37637
281 1H82 FAD 0.0000001235 0.45085 4.37637
282 1O0S NAI 0.0008765 0.44539 4.37637
283 3LU1 NAD 0.0009824 0.42454 4.3956
284 2GAG NAD 0.000000007647 0.61057 4.44444
285 2GAG FAD 0.000000937 0.54522 4.44444
286 2GAG FOA 0.000001098 0.54259 4.44444
287 5KJW 53C 0.009528 0.44255 4.44965
288 2NPX FAD 0.0000004598 0.51167 4.47427
289 2NPX NAD 0.00000157 0.41775 4.47427
290 4BJZ P3A 0.000001454 0.5619 4.48113
291 5OFW 9TW 0.009657 0.44042 4.4843
292 1HYH NAD 0.0001181 0.45633 4.53074
293 1D1T NAD 0.000462 0.42467 4.55764
294 4J36 1HR 0.0000001242 0.57566 4.57831
295 4J36 FAD 0.00000004206 0.57537 4.57831
296 1YY5 FAD 0.00000004797 0.59287 4.59519
297 1RSG FAD 0.00000005709 0.58684 4.59519
298 5TS5 FAD 0.00000002274 0.52887 4.59519
299 5MQ6 NDP 0.00001144 0.52514 4.59519
300 2GMH FAD 0.0000002542 0.49577 4.59519
301 5HSA FAS 0.000002036 0.47039 4.59519
302 2IID FAD 0.0000001001 0.45614 4.59519
303 2IID PHE 0.0000001001 0.45614 4.59519
304 2VZ0 NAP 0.01428 0.40338 4.59519
305 2VZ0 D64 0.01428 0.40338 4.59519
306 4XYB NDP 0.001501 0.40551 4.60358
307 3AD8 NAD 0.000000008233 0.60328 4.70297
308 3AD8 FAD 0.000002889 0.54626 4.70297
309 5ITV NAI 0.00161 0.4027 4.70588
310 4MP8 NAD 0.0005273 0.4315 4.71976
311 2NXE SAM 0.003649 0.43243 4.72441
312 1P77 ATR 0.00001218 0.59592 4.77941
313 5MBX SP5 0.000000174 0.45086 4.814
314 5MBX FAD 0.000000174 0.45086 4.814
315 2AG8 NAP 0.00006023 0.4111 4.814
316 3G89 SAM 0.0002529 0.50062 4.81928
317 5ULP KB1 0.001749 0.42946 4.85075
318 3EGI ADP 0.0008333 0.49767 4.85437
319 1Q1R FAD 0.0000003364 0.51539 4.87239
320 3NT6 FAD 0.0000002443 0.55661 4.87805
321 1UI0 URA 0.04241 0.40383 4.87805
322 4W6Z 8ID 0.002015 0.40879 4.89914
323 3KLJ FAD 0.00000005665 0.57067 4.93506
324 2FR1 NDP 0.0004494 0.43165 4.93827
325 2YYY NAP 0.0003868 0.41813 4.95627
326 5G3U FDA 0.00000005999 0.53408 4.96454
327 5G3U ITW 0.0000003172 0.47879 4.96454
328 3WLE NAD 0.0003521 0.43673 4.98534
329 5LD5 NAD 0.000146 0.47834 5.02793
330 1V59 FAD 0.00000003494 0.59965 5.03282
331 4DSG UDP 0.000002129 0.54666 5.03282
332 1V59 NAD 0.000000004138 0.48151 5.03282
333 4DSG FAD 0.000002129 0.41247 5.03282
334 1YKJ FAD 0.0000009202 0.56314 5.07614
335 1YKJ PHB 0.0000009202 0.40861 5.07614
336 1J49 NAD 0.00004929 0.4468 5.1051
337 5N53 8NB 0.002002 0.47968 5.12821
338 1CER NAD 0.0001672 0.46428 5.13595
339 2PZM UDP 0.000584 0.43665 5.15152
340 2PZM NAD 0.000584 0.43665 5.15152
341 3VPH NAD 0.0004735 0.42803 5.16129
342 3VPH OXM 0.0002719 0.42715 5.16129
343 3FUU ADN 0.0001002 0.40315 5.16605
344 3QFA FAD 0.0000001815 0.49673 5.17241
345 5EOW FAD 0.0000006475 0.52502 5.18518
346 2B9W FAD 0.000001763 0.54563 5.18868
347 1WP4 NDP 0.0004952 0.4421 5.19031
348 2NU8 COA 0.004565 0.4009 5.20833
349 2V3A FAD 0.000000139 0.5657 5.25164
350 1QH5 GBP 0.03803 0.40993 5.25164
351 5KOK SAH 0.01185 0.40591 5.28967
352 1O94 ADP 0.000000004139 0.66327 5.30303
353 1A5Z NAD 0.00001809 0.52164 5.32915
354 1U7T TDT 0.002557 0.41038 5.36398
355 1LDN NAD 0.00009855 0.44504 5.37975
356 5TUK FAD 0.000005044 0.52068 5.39216
357 5HJM MTA 0.004874 0.42325 5.39773
358 3G5S FAD 0.0000002028 0.52209 5.41761
359 4MO2 FDA 0.0000007557 0.50496 5.43478
360 4MO2 FAD 0.0000005972 0.5029 5.43478
361 4AP3 NAP 0.000000001085 0.67685 5.47046
362 3GDN HBX 0.00000159 0.54277 5.47046
363 3GDN FAD 0.0000008579 0.54245 5.47046
364 4AP3 FAD 0.000000001085 0.48137 5.47046
365 1LDM NAD 0.0005534 0.43406 5.47112
366 3F8D FAD 0.00000118 0.56556 5.57276
367 5LOG SAH 0.0006491 0.4625 5.5794
368 1T26 NAI 0.0006199 0.43461 5.59006
369 2A92 NAI 0.000448 0.42559 5.60748
370 1GOJ ADP 0.03028 0.42242 5.6338
371 3L4S NAD 0.0005323 0.42288 5.65476
372 3L4S 3PG 0.0006586 0.42281 5.65476
373 4PLG NAI 0.0004075 0.43565 5.68862
374 2NVK FAD 0.0000002109 0.56388 5.68928
375 4IV9 FAD 0.00000003825 0.52876 5.68928
376 1E1M FAD 0.00000002738 0.47522 5.68928
377 1E1M NAP 0.00000002738 0.47522 5.68928
378 1GTE FAD 0.000001335 0.41703 5.68928
379 2G5C NAD 0.0003391 0.42258 5.69395
380 1TDF FAD 0.0000003902 0.5611 5.6962
381 1TDF NAP 0.000001927 0.55697 5.6962
382 1I0Z NAI 0.0004257 0.43841 5.70571
383 1LSS NAD 0.000002279 0.45702 5.71429
384 9LDB NAD 0.0001291 0.45487 5.72289
385 9LDT NAD 0.0001348 0.44001 5.72289
386 1RYI FAD 0.0000001422 0.57032 5.75916
387 2V6G NAP 0.0007714 0.41457 5.76923
388 5T67 JHZ 0.00333 0.40988 5.76923
389 5T67 SAH 0.004211 0.40122 5.76923
390 4D79 ATP 0.000028 0.5291 5.7971
391 5MPT SAH 0.007545 0.41798 5.7971
392 1MXH DHF 0.002715 0.40625 5.7971
393 1FL2 FAD 0.000000267 0.55683 5.80645
394 5CAE COA 0.0005389 0.45072 5.82278
395 4RSL FAD 0.000006958 0.47809 5.8427
396 1FEC FAD 0.000001293 0.54121 5.9081
397 2Z3Y F2N 0.00000004235 0.51073 5.9081
398 1SC6 NAD 0.0009049 0.41445 5.94059
399 2IVD FAD 0.0000000505 0.54992 6.12691
400 2RGO FAD 0.0000008295 0.53525 6.12691
401 4EUE NAI 0.001195 0.41052 6.12691
402 4CNK FAD 0.00000002817 0.59147 6.13811
403 3GF4 FAD 0.000003507 0.41909 6.15385
404 3GF4 UPG 0.000002182 0.41407 6.15385
405 4YRY FAD 0.00000001634 0.52732 6.15942
406 4YRY NAD 0.0000001121 0.45879 6.15942
407 3H8V ATP 0.000005953 0.43633 6.16438
408 2EG5 SAH 0.01576 0.41311 6.1828
409 1UAY ADN 0.002092 0.45594 6.19835
410 1F8G NAD 0.0003529 0.46602 6.25
411 2Y6Q I7T 0.0000003594 0.56247 6.28141
412 2Y6Q FAD 0.0000001128 0.55463 6.28141
413 1EZ4 NAD 0.0003956 0.44927 6.28931
414 4K28 NAD 0.00008685 0.47961 6.3197
415 1V6A TRE 0.0002614 0.52834 6.3253
416 5FJN BE2 0.0000002335 0.56821 6.34573
417 5FJN FAD 0.0000001789 0.56813 6.34573
418 1NAA 6FA 0.000001001 0.46981 6.34573
419 1KOL NAD 0.0001461 0.45081 6.34573
420 1NAA ABL 0.000002 0.42699 6.34573
421 5F8F SFG 0.004307 0.43662 6.36605
422 2B4R NAD 0.0001204 0.44254 6.37681
423 2B4R AES 0.0002853 0.42565 6.37681
424 2YG3 FAD 0.00000004393 0.52602 6.40177
425 1MUU NAD 0.00003001 0.49845 6.42202
426 1MV8 NAD 0.00001744 0.45322 6.42202
427 2EWM NAD 0.002106 0.40934 6.4257
428 1LLU NAD 0.001828 0.40252 6.43275
429 2NSJ C2R 0.03255 0.40089 6.50888
430 5UAV TFB 0.0006657 0.42653 6.52174
431 5UAV NDP 0.0006657 0.42653 6.52174
432 3VGL BGC 0.02457 0.41458 6.54206
433 1ORR NAD 0.002041 0.40493 6.62824
434 2HJR APR 0.00005336 0.49684 6.70732
435 1ZK7 FAD 0.0000001718 0.48421 6.78337
436 1P31 EPU 0.007644 0.41772 6.78337
437 3HVJ 705 0.0005617 0.43049 6.78733
438 2GZ3 NAP 0.004853 0.40622 6.8306
439 1ZEM NAD 0.0003799 0.4113 6.87023
440 3B1F NAD 0.000009125 0.53446 6.89655
441 1E3W NAD 0.00312 0.40538 6.89655
442 3LZW FAD 0.000000005584 0.56597 6.92771
443 3LZW NAP 0.00000002845 0.45355 6.92771
444 2HMT NAI 0.00000274 0.46011 6.94444
445 4R6W PC 0.003827 0.41267 6.97674
446 1PS9 FAD 0.00000003696 0.59231 7.00219
447 1KNR FAD 0.0000004391 0.55036 7.00219
448 1PS9 NAP 0.00003348 0.44426 7.00219
449 5TUF FAD 0.00000481 0.50445 7.09046
450 3ITJ FAD 0.000000341 0.4633 7.10059
451 3ITJ CIT 0.00956 0.42658 7.10059
452 1UXG NAD 0.0001818 0.4499 7.11974
453 1Y8Q ATP 0.000004281 0.53799 7.22101
454 1HDG NAD 0.0003868 0.45312 7.22892
455 1G55 SAH 0.008889 0.41152 7.28863
456 3GGO NAI 0.0006075 0.43385 7.32484
457 3GGO ENO 0.0006075 0.43385 7.32484
458 4II2 ATP 0.00001388 0.4339 7.36196
459 1NYT NAP 0.002657 0.41893 7.38007
460 1ZMD NAI 0.00000002399 0.6249 7.43983
461 1ZMD FAD 0.00000003151 0.51232 7.43983
462 1COY FAD 0.000006581 0.45583 7.43983
463 1SOW NAD 0.0003064 0.43137 7.43983
464 4ZCC NAI 0.000000329 0.45504 7.44048
465 4ZCC FAD 0.000000329 0.45504 7.44048
466 4GKV NAD 0.001761 0.40853 7.44048
467 1EK6 UPG 0.003389 0.41708 7.47126
468 4YCA NDP 0.0001823 0.46278 7.48299
469 2DT5 NAD 0.00005236 0.4768 7.58294
470 5MZI FAD 0.0000007916 0.41824 7.65864
471 1VKO NAD 0.001088 0.41746 7.65864
472 5MZI FYK 0.0000008427 0.41466 7.65864
473 3FG2 FAD 0.0000003072 0.54397 7.67327
474 2Q7V FAD 0.000000005467 0.54641 7.69231
475 4JK3 NAD 0.0000499 0.43856 7.72201
476 5JCA FAD 0.00000001984 0.52522 7.74648
477 5JCA NDP 0.00000007998 0.43768 7.74648
478 1VDC FAD 0.0000003761 0.56308 7.80781
479 2Q1W NAD 0.0002405 0.44168 7.80781
480 3OFK SAH 0.0003451 0.46645 7.87037
481 5AHO TLA 0.0001309 0.55531 8.03571
482 1H2B NAJ 0.0008535 0.41872 8.07799
483 4J4H NAI 0.0005208 0.44161 8.10811
484 4J4H 1J1 0.0005208 0.44161 8.10811
485 4XUC SAM 0.001926 0.4071 8.25688
486 4XUC 43G 0.001926 0.4071 8.25688
487 5X20 NAD 0.0004328 0.4047 8.33333
488 2VT3 ATP 0.000001422 0.41991 8.37209
489 3UOY NAP 0.0000000005204 0.69733 8.53392
490 4JDR FAD 0.00000001778 0.5321 8.53392
491 3UOY FAD 0.0000000005204 0.46949 8.53392
492 1I9G SAM 0.00003953 0.42332 8.53392
493 3OZ2 FAD 0.0000002621 0.50123 8.56423
494 2AQJ FAD 0.000001709 0.54938 8.75274
495 2AQJ TRP 0.000001645 0.54898 8.75274
496 2P41 SAH 0.00528 0.42508 8.85246
497 2O07 MTA 0.001057 0.4291 8.88158
498 2O07 SPD 0.001705 0.4154 8.88158
499 4WZ6 ATP 0.02094 0.42467 8.96552
500 1JNR FAD 0.0000006834 0.57786 8.97155
501 2JB2 FAD 0.0000001882 0.51214 8.99796
502 2JB2 PHE 0.0000002094 0.50499 8.99796
503 4D3F NAP 0.0002305 0.474 9.03226
504 5DXA SFG 0.005172 0.41273 9.16905
505 5DX8 SFG 0.005639 0.41114 9.16905
506 5DX1 SFG 0.00698 0.40177 9.16905
507 4E13 NAD 0.00006023 0.41092 9.18728
508 1Q9I TEO 0.0000002084 0.44527 9.19037
509 1Q9I FAD 0.0000002084 0.44527 9.19037
510 1I8T FAD 0.000001728 0.52657 9.26431
511 2CDU FAD 0.0000001009 0.56729 9.29204
512 2CDU ADP 0.000000004137 0.5126 9.29204
513 5BUK FAD 0.0000001317 0.57621 9.33333
514 2PHT MAN MAN MAN 0.02531 0.41928 9.52381
515 3CTY FAD 0.00000001935 0.60784 9.71787
516 5EVY FAD 0.0002711 0.46696 9.84683
517 1F3L SAH 0.007063 0.40987 9.96885
518 3DXY SAM 0.0007997 0.48136 10.0917
519 3NDJ SAH 0.004554 0.40557 10.0962
520 3NDJ JHZ 0.004554 0.40557 10.0962
521 3EGV SAH 0.00233 0.44524 10.2041
522 2I7C AAT 0.001114 0.41025 10.2473
523 4G74 FAD 0.000004463 0.48508 10.2845
524 4G74 UQ5 0.000007106 0.43316 10.2845
525 5ODQ FAD 0.0000001333 0.50161 10.3093
526 3Q9T FAY 0.000005964 0.50505 10.5033
527 1JG3 ADN 0.0001625 0.49421 10.5033
528 2X3N FAD 0.0000008451 0.50112 10.5263
529 2PV7 NAD 0.0005665 0.43979 10.7383
530 1HKU NAD 0.0002061 0.44724 10.8939
531 2V3B FAD 0.0000001778 0.56001 10.9091
532 1KYQ NAD 0.000001688 0.44567 10.9489
533 5E8J SAH 0.0009897 0.47178 11.3636
534 5E5U MLI 0.005759 0.42603 11.5578
535 4EMI FAD 0.000000178 0.51833 11.8162
536 4EMI NAD 0.0000005628 0.42097 11.8162
537 1GPE FAD 0.0000005398 0.46975 12.035
538 3RNM FAD 0.00000004467 0.59247 12.069
539 1VBO MAN 0.04014 0.41007 12.0805
540 4QTU SAM 0.001429 0.44714 12.5
541 1XG5 NAP 0.002511 0.40646 12.5448
542 4ZRN NAD 0.0004812 0.4234 12.8205
543 2AWN ADP 0.04041 0.41098 12.8609
544 5E1M SAH 0.002968 0.42945 12.8631
545 1WOQ BGC 0.007497 0.43716 13.1086
546 3L8H FX1 0.03485 0.42975 13.4078
547 1SAY PYR 0.0002543 0.43925 13.5734
548 4NTD FAD 0.0000002334 0.55734 13.8235
549 1GUZ NAD 0.0002243 0.42434 14.5161
550 4UP3 FAD 0.0000003414 0.55445 14.6497
551 4UP3 NDP 0.0002037 0.40379 14.6497
552 1E6E FAD 0.0000000075 0.6089 14.8438
553 1N2X SAM 0.008063 0.40455 14.9502
554 5L95 AMP 0.000009478 0.54472 16.25
555 1DL5 SAH 0.002192 0.41942 16.4038
556 1GV0 NAD 0.0002715 0.42532 16.4516
557 5J7X FAD 0.000000001838 0.58483 17.7243
558 3UCL FAD 0.000000002547 0.66726 18.1619
559 3UCL NAP 0.000000003129 0.66726 18.1619
560 3UCL CYH 0.000000002547 0.66726 18.1619
561 4D04 NAP 0.000000001882 0.66999 18.3807
562 4D04 FAD 0.000000001882 0.47004 18.3807
563 4USQ FAD 0.000000001093 0.63532 19.6676
564 2DC1 NAD 0.0008573 0.40151 19.9153
565 1LOB MMA 0.02554 0.41868 20.442
566 4YSX FAD 0.00000008992 0.51658 20.5128
567 3QV1 NAD 0.00006348 0.48516 20.7317
568 4J56 FAD 0.00000004599 0.59356 21.9298
569 2Q0L FAD 0.00000002498 0.52745 24.4373
570 2Q0L NAP 0.00007362 0.52082 24.4373
571 5BWD FUM 0.02697 0.41777 26.6667
572 4USR FAD 0.0000000001236 0.66745 26.8698
573 2F5Z FAD 0.00000004183 0.59355 28.125
574 2XVF FAD 0.000000000001097 0.7528 41.7943
575 2XVE FAD 0.000000000001569 0.78914 42.6724
Pocket No.: 2; Query (leader) PDB : 1VQW; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1vqw.bio1) has 33 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Feedback