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Receptor
PDB id Resolution Class Description Source Keywords
1V8K 2.25 Å NON-ENZYME: MOBILE THE CRYSTAL STRUCTURE OF THE MINIMAL FUNCTIONAL DOMAIN OF TH MICROTUBULE DESTABILIZER KIF2C COMPLEXED WITH MG-AMPPNP MUS MUSCULUS KINESIN-LIKE PROTEIN MICROTUBULE DESTABILIZER STRUCTURAL P
Ref.: A COMMON MECHANISM FOR MICROTUBULE DESTABILIZERS-M KINESINS STABILIZE CURLING OF THE PROTOFILAMENT USI CLASS-SPECIFIC NECK AND LOOPS. CELL(CAMBRIDGE,MASS.) V. 116 591 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:500;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:501;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1V8K 2.25 Å NON-ENZYME: MOBILE THE CRYSTAL STRUCTURE OF THE MINIMAL FUNCTIONAL DOMAIN OF TH MICROTUBULE DESTABILIZER KIF2C COMPLEXED WITH MG-AMPPNP MUS MUSCULUS KINESIN-LIKE PROTEIN MICROTUBULE DESTABILIZER STRUCTURAL P
Ref.: A COMMON MECHANISM FOR MICROTUBULE DESTABILIZERS-M KINESINS STABILIZE CURLING OF THE PROTOFILAMENT USI CLASS-SPECIFIC NECK AND LOOPS. CELL(CAMBRIDGE,MASS.) V. 116 591 2004
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 1V8K - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 56 families.
1 1V8K - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 39 families.
1 1V8K - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1V8K; Ligand: ANP; Similar sites found with APoc: 780
This union binding pocket(no: 1) in the query (biounit: 1v8k.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1GXU 2HP None
2 4HEQ FMN None
3 2WIC GNP 0.749064
4 3TK1 GDP 0.909091
5 3EWA ANP 0.931677
6 1GWN GTP 0.97561
7 1M7B GTP 1.08696
8 5HR5 ADP 1.21951
9 2DPY ADP 1.21951
10 1OS1 PYR 1.46341
11 4NCN GTP 1.46341
12 5TVJ COA 1.46341
13 1OS1 ATP 1.46341
14 4R98 GNH 1.47601
15 4LC1 GDP 1.48368
16 1YTM ATP 1.50376
17 3U6B GDP 1.52284
18 4G5G GDP 1.52284
19 5JBQ GDP 1.52284
20 3U6K GDP 1.52284
21 2BVN GNP 1.52672
22 1D8T GDP 1.52672
23 1OIX GDP 1.57068
24 1OIV GDP 1.57068
25 3G6K FAD 1.62338
26 3G6K POP 1.62338
27 3EC1 GDP 1.62602
28 3QXC ATP 1.65289
29 1G3M PCQ 1.70068
30 1G3M A3P 1.70068
31 3HU3 AGS 1.70732
32 1G7S GDP 1.70732
33 5LB3 ADP 1.70732
34 3WYA GDP 1.70732
35 3P4X ADP 1.70732
36 2A2C NG1 1.70732
37 2A2C ADP 1.70732
38 6ASY ATP 1.70732
39 4TMZ GSP 1.73913
40 2HV8 GTP 1.74419
41 4PC3 GDP 1.77305
42 2D7C GTP 1.79641
43 1IN4 ADP 1.79641
44 1AKY AP5 1.81818
45 2PZM NAD 1.81818
46 2PZM UDP 1.81818
47 1NST A3P 1.84615
48 4X8O AP5 1.86916
49 1U0J ADP 1.87266
50 1DL5 SAH 1.89274
51 4GOX A3P 1.91693
52 4KBF AMP 1.91781
53 5M04 GDP 1.94444
54 3FVQ ATP 1.94986
55 5LTJ ADP 1.95122
56 1TQ4 GDP 1.95122
57 2GJ8 ALF GDP 1.95122
58 6B4K ANP 1.95122
59 1XKV ATP 1.95122
60 2C9O ADP 1.95122
61 5XDR ADP 1.95122
62 6FAA ADP 1.95122
63 2GKS ADP 1.95122
64 1W5T ANP 1.95122
65 1W5T ADP 1.95122
66 5LTJ BEF 1.95122
67 4JLS 3ZE 1.97368
68 2ZW5 COA 1.99336
69 2OZE AGS 2.01342
70 4UTG ANP 2.02312
71 1J0D 5PA 2.05279
72 4GID 0GH 2.06186
73 4GLL NAD 2.07715
74 1G6O ADP 2.12121
75 5GUD NDP 2.12314
76 1IG0 VIB 2.19436
77 3WXM GTP 2.19512
78 4LYA ATP 2.19512
79 4YS0 ADP 2.19512
80 4ZDJ UTP 2.19512
81 5ZBC FAD 2.19512
82 4BFW ZVW 2.20126
83 1D2N ANP 2.20588
84 2FNA ADP 2.2409
85 4H8N NDP 2.25806
86 1X8J A3P 2.2792
87 3CNL GNP 2.29008
88 5YGE ACO 2.29885
89 5YGE GLU 2.29885
90 4NU0 AP5 2.30415
91 4MKG AP5 2.30415
92 1S3G AP5 2.30415
93 1ZIN AP5 2.30415
94 2AWN ADP 2.3622
95 3RAB GNP 2.36686
96 1Z2A GDP 2.38095
97 4QRH 0O2 2.38095
98 2Q1W NAD 2.4024
99 1V6A TRE 2.40964
100 4ZKD GDP 2.43902
101 5IRN ADP 2.43902
102 1KK1 GNP 2.43902
103 5M7P ADP 2.43902
104 4R43 GDP 2.43902
105 4H1V GNP 2.43902
106 3SXN COA 2.43902
107 1QAN SAH 2.45902
108 2C77 GNP 2.46914
109 2C78 GNP 2.46914
110 5MEX SZZ 2.48447
111 5MEX PAP 2.48447
112 2BO4 FLC 2.51889
113 4Z7X 3CX 2.52101
114 4WEI GLC GAL 2.52708
115 5IFS ADP 2.53165
116 3IO3 ADP 2.58621
117 5W76 GDP 2.5974
118 2PX8 SAH 2.60223
119 3WG6 NDP 2.60586
120 5C9P FUC 2.62467
121 4D9C PMP 2.63158
122 2CHG ANP 2.65487
123 5LLB 6YZ 2.6616
124 1B0U ATP 2.67176
125 1Q20 A3P 2.67559
126 1Q20 PLO 2.67559
127 5W7Q GDP 2.68097
128 2WHX ADP 2.68293
129 4KVA GTP 2.68293
130 5GOE GDP 2.68293
131 1G41 ADP 2.68293
132 1YQT ADP 2.68293
133 5JCP GDP ALF 2.68293
134 5YV5 ADP 2.68293
135 5H7J GCP 2.68293
136 1QF5 GDP 2.68293
137 1QF5 RPL 2.68293
138 3QDK QDK 2.68293
139 2ZPA ADP 2.68293
140 6FDF SAH 2.69461
141 4P8K 38C 2.70833
142 4P8K FAD 2.70833
143 1P4V GLY 2.71186
144 1KY3 GDP 2.74725
145 1VHT BA3 2.75229
146 2ZE7 AMP 2.7668
147 2ZE7 DST 2.7668
148 1D2E GDP 2.77078
149 1EJ0 SAM 2.77778
150 1NN5 ANP 2.7907
151 1NN5 2DT 2.7907
152 2Y8E GNP 2.7933
153 5W75 SUC 2.80612
154 5W75 GDP 2.80612
155 4U5X GNP 2.80899
156 3BER AMP 2.81124
157 1SVK ALF GDP 2.83286
158 1M7G ADX 2.8436
159 1M7G ADP 2.8436
160 1M7G AV2 2.8436
161 5K5Z ANP 2.86624
162 2F3R G5P 2.89855
163 1JJV ATP 2.91262
164 4RD0 GDP 2.92683
165 2JLR ANP 2.92683
166 5G41 AP5 2.92683
167 2JAQ DCP 2.92683
168 2GMV PEP 2.92683
169 2GMV UN8 2.92683
170 1NHX PEP 2.92683
171 1NHX FTB 2.92683
172 3V2U ATP 2.92683
173 5KVA SAM 2.92683
174 2AJ4 ANP 2.92683
175 1RYH GNP 2.95567
176 5THY SAH 2.96296
177 2BIF ANP 2.98507
178 2BIF SIN 2.98507
179 1XP8 AGS 3.00546
180 1F6B GDP 3.0303
181 1Y3A GDP 3.03951
182 1G8S MET 3.04348
183 2ZPT A3P 3.05085
184 3QVV 3QV 3.05085
185 3QVV A3P 3.05085
186 4AG5 ADP 3.06122
187 4NON GDP 3.07692
188 2OM2 GDP 3.07692
189 4ONQ SFG 3.08123
190 4PX9 ADP 3.08219
191 1TAD ALF 3.08642
192 1TAD GDP 3.08642
193 3ZQ6 ADP ALF 3.08642
194 1FP6 ADP 3.11419
195 1OXV ANP 3.11615
196 3MB5 SAM 3.13725
197 2A5J GDP 3.14136
198 5VHC BEF ADP 3.17073
199 1R6B ADP 3.17073
200 2XAU ADP 3.17073
201 4OHY ANP 3.17073
202 4J0Q GDP 3.17073
203 1Z6T ADP 3.17073
204 1BH2 GSP 3.1746
205 4AUT FAD 3.20513
206 1MH1 GNP 3.22581
207 2QQ0 ANP 3.26087
208 2QQ0 ADP 3.26087
209 2QQ0 TMP 3.26087
210 2QQ0 THM 3.26087
211 1G4U GDP 3.26087
212 3DZD ADP 3.26087
213 2J0V GDP 3.30189
214 4LPS GDP 3.30579
215 2WKQ GTP 3.31325
216 6DEF GCP 3.32481
217 2OG2 MLI 3.34262
218 2OFW ADX 3.36538
219 1AQU A3P 3.367
220 1XMV ADP 3.37079
221 2RGX AP5 3.39806
222 4YC7 GNP 3.41207
223 5AK0 8V1 3.41463
224 1K6M AGS 3.41463
225 2GK6 ADP 3.41463
226 1QHG ATP 3.41463
227 1V35 NAI 3.41463
228 3W5J GDP 3.43137
229 3DEF GDP 3.43511
230 1Z0A GDP 3.44828
231 1JJ7 ADP 3.46154
232 4ITR GDP 3.48101
233 2GCN GDP 3.48259
234 2GCO GNP 3.48259
235 2CDN ADP 3.48259
236 2PZE ATP 3.49345
237 3FWY ADP 3.50318
238 4UP3 FAD 3.50318
239 5WDR GNP 3.50877
240 1UPT GTP 3.50877
241 4YDS ATP 3.50877
242 2F9L GDP 3.51759
243 5H7K GDP 3.52645
244 3T1O GDP 3.53535
245 1OFH ADP 3.54839
246 1FL2 FAD 3.54839
247 4WOP CTP 3.55556
248 5IRR GSP 3.57143
249 1SQ5 ADP 3.57143
250 3REF GDP 3.60825
251 1O3Y GTP 3.61446
252 3VX3 ADP 3.62903
253 6CS8 F9Y 3.63036
254 3H86 AP5 3.64583
255 4WZA ACP 3.65854
256 4WZA ADP 3.65854
257 2ZR9 DTP 3.65854
258 4IHQ ADP 3.65854
259 2JJK R15 3.65854
260 5MZN ADP 3.65854
261 1IWE IMP 3.65854
262 3KC1 2T6 3.65854
263 3MD0 GDP 3.66197
264 3T12 GDP ALF 3.67647
265 3FB4 AP5 3.7037
266 3TMK T5A 3.7037
267 3FG2 FAD 3.71287
268 1H74 ADP 3.71622
269 1OW3 GDP 3.71901
270 6AIC AMP 3.73832
271 5WRI A3P 3.75
272 2BME GNP 3.76344
273 6BCA GSP 3.78378
274 4D0N GDP 3.78378
275 1HTW ADP 3.79747
276 2VOH CIT 3.82166
277 5H68 AGS 3.82353
278 4P3Y GDP 3.84615
279 5J1J ANP 3.85965
280 5BYK A3P 3.861
281 5BYK OAQ 3.861
282 1VG0 GDP 3.86473
283 1VG8 GNP 3.86473
284 3SFV GDP 3.8674
285 1NV8 MEQ 3.87324
286 1NV8 SAM 3.87324
287 4E03 ADP 3.8835
288 1SKQ GDP 3.90244
289 2IS6 ADP 3.90244
290 4IEE AGS 3.90244
291 1OYY AGS 3.90244
292 4XGU ADP 3.90244
293 1Q19 APC 3.90244
294 5ERG SAM 3.90244
295 2PEZ DAT 3.91061
296 2PEZ GGZ 3.91061
297 1Z0F GDP 3.91061
298 4Q1A 2XZ 3.92857
299 4Q1A UDP 3.92857
300 1S9D GDP 3.94089
301 5WRJ A3P 3.9604
302 3E70 GDP 3.96341
303 1R18 SAH 3.96476
304 3B9Q MLI 3.97351
305 5IRC GDP 3.9801
306 3ELW SAM 4
307 1Y4Z PCI 4
308 2W2X GSP 4.03226
309 1W0J ADP 4.04412
310 1W0J ADP BEF 4.04412
311 3GJ0 GDP 4.0724
312 4QM7 GTP 4.09357
313 5L3R GCP 4.09556
314 1J99 AND 4.09556
315 6BCB GSP 4.10959
316 1G16 GDP 4.11765
317 3QKT ANP 4.12979
318 1WDT GTP 4.14634
319 5TSH ADP 4.14634
320 5TSH ANP 4.14634
321 4QOS ADP 4.15094
322 1ZUI SKM 4.16667
323 1IBR GNP 4.16667
324 1T3Q FAD 4.16667
325 1BO4 COA 4.16667
326 1P72 ADP 4.19162
327 1GP2 GDP 4.22535
328 2IYL GDP 4.22535
329 1E2K TMC 4.22961
330 3SBD GNP 4.27807
331 4HSE ADP 4.28212
332 4PPF FLC 4.28571
333 5EP2 AZU 4.29688
334 6GAR FAD 4.29799
335 1VG1 GDP 4.32432
336 1VG9 GDP 4.32432
337 2GWH A3P 4.36242
338 1O94 ADP 4.375
339 4LX0 BEF GDP 4.39024
340 4YJ1 ADP 4.39024
341 4IOK XPO 4.39024
342 4IOK ADP 4.39024
343 3RC3 ANP 4.39024
344 1NJF ADP 4.4
345 1NJF AGS 4.4
346 1T8U UAP SGN IDS SGN 4.41176
347 1T8U A3P 4.41176
348 6G14 G4P 4.42177
349 2IXE ATP 4.42804
350 2V2V V12 4.42804
351 1GRN AF3 4.4335
352 1GRN GDP 4.4335
353 1DS6 GDP 4.44444
354 1I4D GDP 4.46429
355 1TX4 ALF GDP 4.54545
356 4BQS ADP 4.54545
357 4BQS K2Q 4.54545
358 6G96 ACO 4.54545
359 3NHB ADP 4.57516
360 5L3W GDP 4.57516
361 1IHU ADP 4.58404
362 1IHU AF3 4.58404
363 1IK4 PGH 4.60526
364 1SVI GDP 4.61538
365 2FJU GSP 4.63415
366 1MR3 G3D 4.63415
367 1MKY GDP 4.63415
368 4DCT GDP 4.63415
369 4PJ3 ANP 4.63415
370 2J0W ASP 4.63415
371 2CBZ ATP 4.64135
372 1TU3 GNP 4.67836
373 2XTN GTP 4.70085
374 1R2Q GNP 4.70588
375 3WR7 COA 4.70588
376 2RCN GDP 4.7486
377 2J59 GTP 4.7619
378 1U8Z GDP 4.7619
379 1UJ2 ADP 4.7619
380 1UJ2 C5P 4.7619
381 2X77 GDP 4.7619
382 3GPO APR 4.7619
383 3TLJ SAH 4.82574
384 5G3Y ADP 4.86726
385 2HF9 GSP 4.86726
386 2FAH GDP 4.87805
387 4R2I ANP 4.87805
388 2I4I AMP 4.87805
389 1E96 GTP 4.92611
390 3N5C GDP 4.93827
391 1APZ ASP 4.93827
392 4GBM A3P 4.95356
393 1PUJ GNP 4.96454
394 5XKT GNP 5
395 2QG6 NMN 5.02513
396 3EZ2 ADP 5.02513
397 3A1S GDP 5.03876
398 2VZZ SCA 5.04587
399 3E5H GNP 5.05618
400 2BEK ATP 5.05837
401 1CR1 TTP 5.06757
402 4MKF AP5 5.06912
403 3VMF GTP 5.09383
404 1WA5 GTP 5.11364
405 4IDN GNP 5.12195
406 5ZXD ATP 5.12195
407 3Q9L ATP 5.12195
408 5I34 GDP 5.12195
409 2NGR GDP 5.12821
410 2NGR AF3 5.12821
411 1QF9 ALF 5.15464
412 1QF9 C5P 5.15464
413 1QF9 ADP 5.15464
414 1NY5 ADP 5.16796
415 2ZTS ADP 5.17928
416 2O66 FLC 5.18518
417 2D2F ADP 5.2
418 3GJX GTP 5.20548
419 1HSK FAD 5.21472
420 2GQT FAD 5.22388
421 1A4R GDP 5.2356
422 1A4R GNH 5.2356
423 1XX6 ADP 5.2356
424 2YOH WMJ 5.2381
425 4PVV HO4 5.24691
426 1WG8 SAM 5.26316
427 2B4D COA 5.26316
428 5JCZ GDP 5.28967
429 4D81 ADP 5.30035
430 1YRB GDP 5.34351
431 1ZJ6 G3D 5.34759
432 5L3V GDP 5.35117
433 5VGR GDP 5.36585
434 5L3S GNP 5.36913
435 5L3S G 5.36913
436 5KSZ GCP 5.42453
437 1V0C ACO 5.44554
438 1V0C KNC 5.44554
439 4V03 ADP 5.44747
440 1R4A GNP 5.45455
441 5X40 ACP 5.47945
442 3UIE ANP 5.5
443 5BXQ GDP 5.51181
444 3KJI ADP 5.51181
445 5E5U MLI 5.52764
446 1L2T ATP 5.53191
447 1D5C GDP 5.55556
448 3T34 GDP 5.55556
449 4KOT CE3 5.55556
450 3TKL GTP 5.60976
451 1LVK MNT BEF 5.60976
452 2QTV GNP 5.60976
453 1M2O GNP 5.60976
454 1Z83 AP5 5.61225
455 6EDV COA 5.6701
456 2GDJ ANP 5.68182
457 2QEN ADP 5.71429
458 2JEV NHQ 5.74713
459 4FCW ADP 5.78778
460 5BQ5 ADP BEF 5.82011
461 3ZJ0 ACO 5.82524
462 2WJG GDP 5.85106
463 3R96 ACO 5.85106
464 3R96 AMP 5.85106
465 3PCR GTP 5.85366
466 5BN3 ADP 5.85366
467 1F5N GNP 5.85366
468 5O74 GDP 5.85366
469 2WME NAP 5.85366
470 2WOX NDP 5.85366
471 5J1S ATP 5.85774
472 3GJ5 GDP 5.88235
473 3FKQ ATP 5.89812
474 4LJ9 ACP 5.8997
475 4Y4V DAL 5.8997
476 5Z69 AGS 5.91398
477 1HE1 AF3 5.92593
478 1HE1 GDP 5.92593
479 3RWO GDP 5.94595
480 3AQ4 GDP 5.97826
481 5H4S RAM 5.98592
482 5BW4 SAM 5.99251
483 5OEC GDP 6.01093
484 5CK5 GDP 6.01266
485 5FVJ ACO 6.0241
486 2G77 GDP 6.06061
487 2G77 AF3 6.06061
488 5ZB0 TYD 6.06061
489 5ZB0 ADP 6.06061
490 5DI3 GNP 6.08365
491 2WMO GTP 6.09756
492 4YLG GDP 6.09756
493 5FHD ADP ALF 6.09756
494 1ZD9 GDP 6.09756
495 5FTB ANP 6.09756
496 2CE7 ADP 6.09756
497 3LAD FAD 6.09756
498 1RM6 FAD 6.09756
499 3DKP ADP 6.12245
500 5UIV ADP 6.1674
501 3B5J 12D 6.17284
502 4WZ6 ATP 6.2069
503 2XTZ GSP 6.21469
504 1G6H ADP 6.22568
505 3LXR GDP 6.25
506 1JI0 ATP 6.25
507 3BFV ADP 6.27306
508 4JLV ADP 6.3197
509 1DAR GDP 6.34146
510 2FSH ANP 6.34146
511 1Z06 GNP 6.34921
512 1XPJ TLA 6.34921
513 5U32 GDP 6.35593
514 2PL3 ADP 6.35593
515 6AU6 GDP 6.36605
516 2A9K GDP 6.41711
517 4DKX GDP 6.48148
518 3FYH ADP 6.52174
519 5NUL FMN 6.52174
520 4HI0 GDP 6.53266
521 4U00 ADP 6.55738
522 1KSH GDP 6.57895
523 3IUY AMP 6.57895
524 2WJH GDP 6.62651
525 2WJH FLC 6.62651
526 1R0X ATP 6.64336
527 1RRC ADP 6.64452
528 1J2J GTP 6.66667
529 5TIV A3P 6.71937
530 2F5X ASP 6.73077
531 2A5F GTP 6.73575
532 2EFE GNH 6.74157
533 3F6R FMN 6.75676
534 5XC5 GTP 6.81818
535 4YMU ATP 6.81818
536 3M1I GTP 6.82927
537 3WYF GTP 6.82927
538 5FG3 GDP 6.82927
539 5G09 6DF 6.8323
540 4ZI2 GNP 6.84211
541 1UAD GNP 6.85714
542 4GOJ GNP 6.87831
543 4B47 GDP 6.88705
544 1UKZ ADP 6.89655
545 1RJ9 GCP 6.90789
546 5EXT ADP 6.92308
547 4ZNL BEF ADP 6.93431
548 4OI4 ATP 6.95652
549 1WF3 GNP 6.97674
550 1H65 GDP 7.03704
551 2Z5F A3P 7.04698
552 4M9Q GNP 7.04846
553 1X6V ADP 7.07317
554 4A4Z ANP 7.07317
555 5K04 COA 7.07317
556 1OBV FMN 7.10059
557 4P4T GDP 7.22222
558 3IIJ ADP 7.22222
559 6B8B ADP 7.22892
560 3R7F CP 7.23684
561 6BSX E7S 7.30337
562 6BSX GDP 7.30337
563 2B8W ALF 5GP 7.31707
564 3TBK ANP 7.31707
565 1FFU FAD 7.31707
566 1OE0 TTP 7.3913
567 5EE5 GTP 7.51174
568 1CS4 GSP 7.54717
569 3CPJ GDP 7.62332
570 2J5V PCA 7.62943
571 3Q85 GNP 7.69231
572 4V0K GDP 7.69231
573 5YT0 GDP 7.69231
574 3PQC GDP 7.69231
575 1VKJ A3P 7.7193
576 6CRK GDP 7.72201
577 1ZCB GDP 7.73481
578 3AB3 GDP 7.73481
579 2OBM ADP 7.78098
580 2QZ4 ADP 7.80488
581 2CJW GDP 7.8125
582 2F5Z FAD 7.8125
583 4QC6 30N 7.82123
584 4HUT ATP 7.8534
585 4TL6 ANP 7.90514
586 1KO8 6PG 8
587 2FFQ GSP 8.18713
588 1W4R TTP 8.20513
589 1GOT GDP 8.21918
590 1YZQ GNP 8.23529
591 3CX8 GSP 8.28402
592 3T5G GDP 8.28729
593 4ZOH FAD 8.33333
594 1NM5 NAD 8.37438
595 4C4P GNP 8.41121
596 3Q72 GNP 8.43373
597 3ZS9 ADP ALF 8.47458
598 2WOJ ADP ALF 8.47458
599 4XTR ATP 8.47458
600 4XVU ATP 8.47458
601 4XTR ADP 8.47458
602 1DAK ADP 8.48214
603 1DAK DPU 8.48214
604 1G7C 5GP 8.51064
605 2HT6 GDP 8.62069
606 6BC0 GSP 8.66667
607 5Z2M GTP 8.69565
608 1Y63 ADP 8.69565
609 4KAX GTP 8.69565
610 4UXH T5A 8.69565
611 4K81 GTP 8.77193
612 1FZQ GDP 8.83978
613 3KAP FMN 8.84354
614 2W58 ADP 8.91089
615 2PWY SAH 8.91473
616 4KVG GTP 8.92857
617 1LFD GNP 8.98204
618 6D5G GNP 8.98204
619 6D55 GNP 8.98204
620 6BVJ GNP 8.98204
621 6D59 GNP 8.98204
622 6D56 GNP 8.98204
623 6D5J GNP 8.98204
624 6D5L GNP 8.98204
625 6BVL GNP 8.98204
626 6BVM GNP 8.98204
627 6D5E GNP 8.98204
628 6BVI GNP 8.98204
629 6D5V GNP 8.98204
630 6D5H GNP 8.98204
631 6BVK GNP 8.98204
632 1GUA GNP 8.98204
633 1KAO GDP 8.98204
634 6D5M GNP 8.98204
635 5WC2 ADP 9.02439
636 2UZI GTP 9.03614
637 3DDC GNP 9.03614
638 3KUD GDP 9.03614
639 1CLU DBG 9.03614
640 1NVV GNP 9.03614
641 4BAS GNP 9.04523
642 5UWP GNP 9.09091
643 5DIF GNP 9.09091
644 5UWI GNP 9.09091
645 5UWQ GNP 9.09091
646 5UWR GNP 9.09091
647 5UWJ GNP 9.09091
648 5UWU GNP 9.09091
649 5UWW GNP 9.09091
650 5UWS GNP 9.09091
651 6CIT GNP 9.09091
652 5UWT GNP 9.09091
653 5UWO GNP 9.09091
654 5DHF GNP 9.09091
655 2W83 GTP 9.09091
656 3GJ3 GDP 9.09091
657 5DI9 GNP 9.09091
658 4RZ3 ADP 9.15254
659 1NRJ GTP 9.17431
660 5HCN GCP 9.1954
661 1FNN ADP 9.2545
662 4HAT GNP 9.28571
663 1F2U ATP 9.39597
664 2C5L GTP 9.40171
665 1Z08 GNP 9.41177
666 4KFU ACP 9.43396
667 5KDO GDP 9.45946
668 4NE2 ADP 9.5122
669 4NE2 SH2 9.5122
670 1P9B GDP 9.5122
671 1N62 FAD 9.63855
672 2QN6 GDP 9.67742
673 2FH5 GTP 9.81308
674 2ORV 4TA 9.82906
675 1L3I SAH 9.89583
676 3QF7 ANP 10
677 1LK7 DER 10.0437
678 1X1R GDP 10.1124
679 1QHH ATP 10.1796
680 1FQK GDP 10.2041
681 1FQK ALF 10.2041
682 4CVN ADP 10.219
683 1RE0 GDP 10.4072
684 1SVM ATP 10.4878
685 5Y6N ADP 10.4878
686 4DID GDP 10.5263
687 1WQ1 GDP 10.7784
688 1WQ1 AF3 10.7784
689 2BCG GDP 11.165
690 3GDH SAH 11.2033
691 1KMQ GNP 11.413
692 4XSH GSP 11.4155
693 1QXA GLY GLY GLY 11.4894
694 1ZC3 GNP 11.5044
695 1ION ADP 11.5226
696 3A4M ADP 11.5385
697 4TTQ ATP 11.6279
698 4XOI GTP 11.6667
699 1YVD GNP 11.8343
700 1S7N COA 12.0879
701 5KSP GDP 12.1053
702 5LEF GTP 12.1212
703 5E95 GDP 12.3711
704 1YZN GNP 12.4324
705 3ZIA ADP 12.439
706 3ZIA ATP 12.439
707 1NF3 GNP 12.5
708 3BFX A3P 12.5
709 1G3Q ADP 12.6582
710 5OCG GNP 12.6984
711 5UQW GDP 12.6984
712 3DOE GTP 12.7273
713 2EW1 GNP 12.9353
714 5TAR GDP 12.973
715 5TB5 GDP 12.973
716 2B8T THM 13.0045
717 5DUS APR 13.0952
718 3WYG GTP 13.1579
719 2VBQ BSJ 13.3333
720 1EK0 GNP 13.5294
721 3NKV GNP 13.7143
722 5KUT GDP 13.7566
723 6FA4 GNP 13.8728
724 3PA8 621 13.9024
725 1N07 FMN 14.1104
726 1N07 ADP 14.1104
727 1S8F GDP 14.1243
728 2ZEJ GDP 14.1304
729 3RLF ANP 14.1892
730 5O2T GSP 14.2012
731 5WLB GNP 14.4578
732 1WWZ ACO 14.4654
733 1XEX ATP 14.8352
734 3KTA AP5 14.8352
735 2ODE ALF GDP 14.8571
736 4HDO GNP 14.9701
737 4HDQ GNP 14.9701
738 3X1Z GNP 14.9701
739 5H67 ATP 15
740 3GJ4 GDP 15.1515
741 1Z0J GTP 15.2542
742 6C90 ADP 15.3846
743 3BOS CDP 15.7025
744 4M6T SAM 15.847
745 5GVR LMR 16.6667
746 1FQJ ALF 16.6667
747 1FQJ GDP 16.6667
748 5SZH GNP 16.9935
749 3CH5 GDP 17.3077
750 1YZG GDP 17.8771
751 1CXZ GSP 18.6047
752 1Z0K GTP 18.8406
753 5MVR ADP 19.1358
754 4TMK T5A 19.2488
755 4LHW GNP 19.5402
756 3QBT GNP 19.5402
757 3TNF GNP 19.5402
758 2V7Q ATP 20
759 2CK3 ADP 20
760 2CK3 ANP 20
761 2V7Q ADP 20
762 4D0G GTP 20.2899
763 3MJH GTP 20.5882
764 3GJ8 GDP 20.6522
765 5UPK GNP 20.8333
766 3GJ7 GDP 21.4286
767 2HCJ GDP 21.6216
768 1LVG ADP 22.7273
769 3BC1 GNP 23.7288
770 3RNM FAD 25.8621
771 3B7G ANP 26.5217
772 2D7D ADP 30
773 3WY9 GDP 31.25
774 5UWH GNP 40.9091
775 3H4S ADP 46.6321
776 4FRZ ADP 46.6321
777 3DC4 ADP 47.093
778 3COB ADP 47.4255
779 1GOJ ADP 47.6056
780 6A20 ADP 48.5366
Pocket No.: 2; Query (leader) PDB : 1V8K; Ligand: ANP; Similar sites found with APoc: 2
This union binding pocket(no: 2) in the query (biounit: 1v8k.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 3VPD CIT 2.84698
2 5J7X FAD 3.90244
Pocket No.: 3; Query (leader) PDB : 1V8K; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1v8k.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1V8K; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1v8k.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1V8K; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1v8k.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
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