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Receptor
PDB id Resolution Class Description Source Keywords
1V5F 1.8 Å EC: 1.2.3.3 CRYSTAL STRUCTURE OF PYRUVATE OXIDASE COMPLEXED WITH FAD AND AEROCOCCUS VIRIDANS AEROCOCCUS VIRIDANS OXIDOREDUCTASE FLAVOPROTEIN
Ref.: THE STRUCTURES OF PYRUVATE OXIDASE FROM AEROCOCCUS WITH COFACTORS AND WITH A REACTION INTERMEDIATE REV FLEXIBILITY OF THE ACTIVE-SITE TUNNEL FOR CATALYSIS ACTA CRYSTALLOGR.,SECT.F V. 63 900 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:1601;
 Valid;
 none;
 submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
MG A:1603;
 Part of Protein;
 none;
 submit data
24.305 Mg [Mg+2...
SO4 A:1604;
A:1605;
A:1606;
A:1607;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
96.063 O4 S [O-]S...
TPP A:1602;
 Valid;
 none;
 submit data
425.314 C12 H19 N4 O7 P2 S Cc1c(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1V5F 1.8 Å EC: 1.2.3.3 CRYSTAL STRUCTURE OF PYRUVATE OXIDASE COMPLEXED WITH FAD AND AEROCOCCUS VIRIDANS AEROCOCCUS VIRIDANS OXIDOREDUCTASE FLAVOPROTEIN
Ref.: THE STRUCTURES OF PYRUVATE OXIDASE FROM AEROCOCCUS WITH COFACTORS AND WITH A REACTION INTERMEDIATE REV FLEXIBILITY OF THE ACTIVE-SITE TUNNEL FOR CATALYSIS ACTA CRYSTALLOGR.,SECT.F V. 63 900 2007
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1V5E - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 1V5F - TPP C12 H19 N4 O7 P2 S Cc1c(sc[n+....
3 1V5G - HTL C14 H21 N4 O8 P2 S Cc1c(sc([n....
4 2DJI - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1V5E - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 1V5F - TPP C12 H19 N4 O7 P2 S Cc1c(sc[n+....
3 1V5G - HTL C14 H21 N4 O8 P2 S Cc1c(sc([n....
4 2DJI - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4KGD - TDP C12 H18 N4 O7 P2 S Cc1c(sc[n+....
2 2EZ8 - PYR C3 H4 O3 CC(=O)C(=O....
3 4FEG - PYR C3 H4 O3 CC(=O)C(=O....
4 1POX - TPP C12 H19 N4 O7 P2 S Cc1c(sc[n+....
5 2EZT - PYR C3 H4 O3 CC(=O)C(=O....
6 1Y9D - TPP C12 H19 N4 O7 P2 S Cc1c(sc[n+....
7 2EZ9 - TDK C15 H26 N4 O11 P3 S Cc1c(sc([n....
8 2EZ4 - TPP C12 H19 N4 O7 P2 S Cc1c(sc[n+....
9 1POW - TPP C12 H19 N4 O7 P2 S Cc1c(sc[n+....
10 4FEE - PYR C3 H4 O3 CC(=O)C(=O....
11 2EZU - HTL C14 H21 N4 O8 P2 S Cc1c(sc([n....
12 1V5E - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
13 1V5F - TPP C12 H19 N4 O7 P2 S Cc1c(sc[n+....
14 1V5G - HTL C14 H21 N4 O8 P2 S Cc1c(sc([n....
15 2DJI - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Ligand no: 2; Ligand: TPP; Similar ligands found: 47
No: Ligand ECFP6 Tc MDL keys Tc
1 TPP 1 1
2 V4E 0.891892 1
3 TDP 0.84 0.985714
4 TPS 0.816901 0.957143
5 TMV 0.769231 0.958333
6 2TP 0.725 0.932432
7 VNP 0.721519 0.958904
8 VIB 0.621622 0.75
9 PYI 0.581395 0.887324
10 TDW 0.566667 0.972222
11 HTL 0.566667 0.958904
12 AUJ 0.55914 0.921053
13 N1T 0.556818 0.985714
14 FTP 0.551724 0.835616
15 THV 0.548387 0.958904
16 TPW 0.546512 0.9
17 WWF 0.542553 0.933333
18 TD6 0.540816 0.921053
19 THY 0.536842 0.945946
20 TOG 0.536082 0.921053
21 TDL 0.53125 0.897436
22 THW 0.530612 0.958904
23 TD8 0.53 0.921053
24 TD9 0.53 0.921053
25 TDK 0.525773 0.921053
26 D7K 0.490566 0.909091
27 S1T 0.489362 0.887324
28 R1T 0.489362 0.887324
29 TPU 0.483146 0.842105
30 5SR 0.479167 0.945205
31 T6F 0.476636 0.897436
32 T5X 0.476636 0.897436
33 1U0 0.474227 0.84
34 8PA 0.459459 0.945946
35 8FL 0.457447 0.894737
36 8EO 0.457447 0.92
37 TZD 0.451613 0.883117
38 O2T 0.45098 0.909091
39 TDM 0.443299 0.894737
40 8EL 0.442105 0.894737
41 G8G 0.44086 0.805195
42 TDN 0.415842 0.871795
43 THD 0.411765 0.839506
44 8N9 0.411765 0.839506
45 MP5 0.407895 0.676056
46 TD7 0.40566 0.85
47 DPX 0.4 0.734177
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1V5F; Ligand: FAD; Similar sites found with APoc: 321
This union binding pocket(no: 1) in the query (biounit: 1v5f.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
1 4WBD CIT 1.2939
2 2IYL GDP 1.40845
3 3SSO SAH 1.43198
4 4UXM BE7 1.51515
5 4FRZ ADP 1.5544
6 4IHQ ADP 1.55945
7 1A5Z NAD 1.5674
8 5W7K SAH 1.60256
9 1SQF SAM 1.6317
10 3PT9 SAH 1.69779
11 5LOG SAH 1.71674
12 4BLW SAH 1.7301
13 5M58 SAH 1.73913
14 3GU3 SAH 1.76056
15 5KOK SAH 1.76322
16 3D1R FBP 1.78042
17 4LHD GLY 1.86757
18 2EG5 SAH 1.88172
19 6ECU SAH 1.89873
20 6ECW SAH 1.90476
21 1FUR MLT 1.92719
22 3VPH OXM 1.93548
23 1FP2 SAH 1.98864
24 1ITZ TPP 2.03735
25 2C42 PYR 2.03735
26 2C42 TPP 2.03735
27 4KVL PLM 2.03735
28 2XAU ADP 2.03735
29 6FAA ADP 2.03735
30 1RJW ETF 2.0649
31 4KRI SAH 2.07852
32 2YX1 SFG 2.08333
33 3TKY SAH 2.17391
34 3RFV 15L 2.24719
35 3G2O SAM 2.34114
36 3ICT ADP 2.38095
37 1PJS NAD 2.407
38 5A96 GTP 2.40964
39 3G89 SAM 2.40964
40 3GEG NAD 2.42915
41 2VDV SAM 2.43902
42 1UAY ADN 2.47934
43 3VSE SAH 2.51256
44 1BW9 NAD 2.52809
45 5B47 TPP 2.54669
46 1X87 NAD 2.54669
47 5B47 PYR 2.54669
48 1DJN ADP 2.54669
49 1LK7 DER 2.62009
50 5ZI9 FLC 2.69231
51 4X1B MLI 2.71647
52 5U83 ZN8 2.83019
53 6FTB M0E 2.85714
54 3HWW AKG 2.8777
55 1UP7 NAD 2.8777
56 1Y8Q ATP 2.89017
57 6EQS BV8 2.90909
58 2EJU SAH 2.91005
59 3RIY NAD 2.9304
60 1IZC PYR 2.94985
61 5X62 SAH 2.95567
62 1FP1 SAH 2.95699
63 3LCC SAH 2.97872
64 3A25 SAM 2.99003
65 1KYZ SAH 3.0137
66 2BZG SAH 3.01724
67 5TSH ADP 3.06122
68 5TSH ANP 3.06122
69 4RDI ATP 3.125
70 4RDH AMP 3.125
71 4PPF FLC 3.14286
72 2NXE SAM 3.14961
73 4JJF FE9 3.19767
74 1CDO NAD 3.20856
75 4KRG SAH 3.21888
76 2UYQ SAM 3.22581
77 4D79 ATP 3.26087
78 4LC1 GDP 3.2641
79 1KYQ NAD 3.28467
80 5YF1 SFG 3.31492
81 2OG2 MLI 3.34262
82 4YAC NAI 3.367
83 3L9W GSH 3.38983
84 3L9W AMP 3.38983
85 2O1S TDP 3.39559
86 4DDY DN6 3.42205
87 2PT9 S4M 3.42679
88 1QS0 TDP 3.4398
89 3CBG SAH 3.44828
90 2FK8 SAM 3.45912
91 1G60 SAM 3.46154
92 5E72 SAM 3.46821
93 3OJO NAD 3.48028
94 5XJ7 87O 3.48259
95 4N14 WR7 3.50318
96 3VC1 SAH 3.52564
97 1I1N SAH 3.53982
98 4C4A SAH 3.56537
99 4B2D SER 3.64964
100 5WP5 SAH 3.66599
101 4II2 ATP 3.68098
102 4A6D SAM 3.68272
103 2VVG ADP 3.71429
104 3KLL MAL 3.73514
105 1OBB NAD 3.75
106 1G55 SAH 3.79009
107 4DMG SAM 3.81679
108 1WG8 SAM 3.85965
109 5WP4 SAH 3.86965
110 2I7C AAT 3.88693
111 2JHP SAH 3.90492
112 2EFJ SAH 3.90625
113 1LVL NAD 3.93013
114 5DNK SAH 3.97112
115 5HJM MTA 3.97727
116 5ZW3 SAH 4
117 1T5C ADP 4.01146
118 1P1C SAH 4.0201
119 3LST SAH 4.02299
120 1YC5 NCA 4.06504
121 4BUZ NAD 4.06504
122 4BUZ OCZ 4.06504
123 4BUZ OAD 4.06504
124 3WV8 ATP 4.12844
125 3OFK SAH 4.16667
126 1L1E SAH 4.18118
127 3BXO SAM 4.1841
128 1GOJ ADP 4.22535
129 4PFT MAB 4.22794
130 6BQ6 TER 4.22961
131 3BGD SAH 4.23077
132 1JG3 ADN 4.25532
133 6HOY AR6 4.30464
134 6HOY TSN 4.30464
135 5KVA SAM 4.31655
136 3TKA SAM 4.32277
137 1O97 FAD 4.375
138 1O97 AMP 4.375
139 3ZG6 APR 4.39189
140 1V59 NAD 4.39331
141 4QTU SAM 4.44444
142 2JJQ SAH 4.47059
143 4NZ6 DGL 4.47284
144 3U31 NAD 4.48276
145 1XDS SAM 4.54545
146 1QZZ SAM 4.54545
147 4L2I FAD 4.56274
148 1NJR XYL 4.57746
149 5XNC MTA 4.58221
150 3B9Q MLI 4.63576
151 4OBW SAM 4.66926
152 3FGZ BEF 4.6875
153 5ESO TDP 4.70383
154 5ESO ISC 4.70383
155 6FDF SAH 4.79042
156 2YVK MRU 4.81283
157 5JGL SAM 4.84429
158 1R18 SAH 4.84582
159 1C3X 8IG 4.88722
160 5B48 TDN 4.91803
161 3ABI NAD 4.93151
162 3DUW SAH 4.93274
163 5A3B APR 4.9505
164 5FA8 SAM 4.96894
165 3C3Y SAH 5.06329
166 1S7G NAD 5.13834
167 1S7G APR 5.13834
168 4RL4 PPV 5.18868
169 3T7S SAM 5.22388
170 2O07 MTA 5.26316
171 2O07 SPD 5.26316
172 2OFW ADX 5.28846
173 3GCZ SAM 5.31915
174 1ZPD DPX 5.45775
175 1GXU 2HP 5.49451
176 3EXH TPP 5.49738
177 1EJ0 SAM 5.55556
178 2HMT NAI 5.55556
179 2NGR GDP 5.55556
180 1IHU AF3 5.60272
181 5BW4 SAM 5.61798
182 4BQS ADP 5.68182
183 4AZW SAM 5.73248
184 2OZL TPP 5.75342
185 5ZZ6 ADP 5.76923
186 2AOT SAH 5.82192
187 4KIB SAH 5.88235
188 3H2B SAH 5.91133
189 2X7J TPP 5.94228
190 3AHC TPP 5.94228
191 1OLS TDP 6
192 3A4M ADP 6.15385
193 3DVA TPW 6.15385
194 3GDH SAH 6.22407
195 4Y9D NAI 6.22951
196 3GWZ SAH 6.23306
197 1DL5 SAH 6.30915
198 5MGZ SAH 6.35593
199 4KXQ APR 6.40569
200 5JVB 2PO 6.42857
201 2AWN ADP 6.56168
202 1PNO NAP 6.66667
203 3H4S ADP 6.66667
204 5D4V SAH 6.71642
205 1PL6 NAD 6.74157
206 3GRU AMP 6.77966
207 3DXY SAM 6.88073
208 1FP6 ADP 6.92042
209 2FKA BEF 6.97674
210 3EGI ADP 7.28155
211 1ZGA SAH 7.28291
212 1L3I SAH 7.29167
213 4I5I NAD 7.31707
214 5OJ7 AR6 7.34266
215 5L95 AMP 7.5
216 2BZ1 TAU 7.65306
217 3ITJ CIT 7.69231
218 1NV8 SAM 7.74648
219 1NV8 MEQ 7.74648
220 3W5J GDP 7.84314
221 2HNK SAH 7.94979
222 5N5D SAM 7.9646
223 1N07 ADP 7.97546
224 1M7G AV2 8.05687
225 5O2J 2PO 8.05861
226 2OOR TXP 8.07292
227 4FZV SAM 8.07799
228 3A27 SAM 8.08823
229 2DPM SAM 8.09859
230 1DJL NAP 8.21256
231 5E5U MLT 8.54271
232 5EXE 5SR 8.59873
233 1QAN SAH 8.60656
234 2CDU ADP 8.62832
235 1APZ ASP 8.64198
236 1WY7 SAH 8.69565
237 2ZIF SAM 8.75421
238 2UVO NDG 8.77193
239 2UVO NAG 8.77193
240 4AML GYU 8.77193
241 5BQ5 ADP BEF 8.99471
242 5NM7 GLY 9.02256
243 1G8K MGD 9.02256
244 1JQ3 AAT 9.12162
245 4IF4 BEF 9.13461
246 1D4O NAP 9.23913
247 5JE8 NAD 9.27152
248 2VT3 ATP 9.30233
249 2Y65 ADP 9.31507
250 1UMD TDP COI 9.53679
251 4YMH SAH 9.58333
252 6ECT SAM 9.65732
253 1K7V NAG GAL BGC 9.67742
254 3VYW SAM 9.74026
255 1EFV AMP 9.80392
256 1EFV FAD 9.80392
257 1IM8 SAI 9.83607
258 3V1S 0LH 9.93789
259 4IWN GEK 10.0437
260 1N2X SAM 10.299
261 3I53 SAH 10.8434
262 3MAG SAH 12.0521
263 2PWY SAH 12.4031
264 3MCT SAH 12.4579
265 4CQM NAP 12.6437
266 2QQF A1R 12.6623
267 2OD9 A1R NCA 12.6623
268 1M2K APR 12.8514
269 1SZD APR 13.1313
270 5GM1 SAH 13.1313
271 3FUU ADN 13.2841
272 3JWH SAH 13.3641
273 1LSS NAD 13.5714
274 6F5Z SAH 13.8528
275 4POO SAM 14.5
276 4PIO AVI 14.5511
277 4PIO SAH 14.5511
278 2PEZ DAT 15.0838
279 2VOH CIT 15.3846
280 1L5Y BEF 18.0645
281 1ZQ9 SAM 18.2456
282 5BSZ SAH 19.2
283 5FA5 MTA 20
284 2XKO AKG 20.2247
285 1W85 TDP 24.4898
286 2VK4 TPP 33.3925
287 1QPB PYM 33.5702
288 1QPB TPP 33.5702
289 2KIN ADP 34
290 2C31 TZD 36.9718
291 2C31 ADP 36.9718
292 2VBF TPP 37.0175
293 2Q28 TPP 37.766
294 2Q28 ADP 37.766
295 2NXW TPP 38.2301
296 1YBH P22 38.7097
297 1YBH FAD 38.7097
298 4D5G FAD 38.7097
299 4D5G TPP 38.7097
300 2IHT TPP 41.0122
301 1UPA TPP 41.0122
302 2IHU TP9 41.8848
303 3FSJ D7K 42.2348
304 3IAE D7K 42.6316
305 6DEN TP9 42.9542
306 6DEN G8A 42.9542
307 6DEN FAD 42.9542
308 4RJK TPP 43.0823
309 4RJK TDL 43.0823
310 2UZ1 TPP 43.1616
311 1T9D P22 43.9728
312 1T9D FAD 43.9728
313 5WKC FAD 43.9728
314 1T9D 1MM 43.9728
315 1T9D P25 43.9728
316 5WKC TP9 43.9728
317 5WKC AUJ 43.9728
318 1T9D PYD 43.9728
319 1OZH HE3 44.8763
320 3EYA FAD 47.9053
321 3EYA TDP 47.9053
Pocket No.: 2; Query (leader) PDB : 1V5F; Ligand: FAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1v5f.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1V5F; Ligand: FAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1v5f.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1V5F; Ligand: FAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1v5f.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1V5F; Ligand: TPP; Similar sites found with APoc: 321
This union binding pocket(no: 5) in the query (biounit: 1v5f.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
1 4WBD CIT 1.2939
2 2IYL GDP 1.40845
3 3SSO SAH 1.43198
4 4UXM BE7 1.51515
5 4FRZ ADP 1.5544
6 4IHQ ADP 1.55945
7 1A5Z NAD 1.5674
8 5W7K SAH 1.60256
9 1SQF SAM 1.6317
10 3PT9 SAH 1.69779
11 5LOG SAH 1.71674
12 4BLW SAH 1.7301
13 5M58 SAH 1.73913
14 3GU3 SAH 1.76056
15 5KOK SAH 1.76322
16 3D1R FBP 1.78042
17 4LHD GLY 1.86757
18 2EG5 SAH 1.88172
19 6ECU SAH 1.89873
20 6ECW SAH 1.90476
21 1FUR MLT 1.92719
22 3VPH OXM 1.93548
23 1FP2 SAH 1.98864
24 1ITZ TPP 2.03735
25 2C42 PYR 2.03735
26 2C42 TPP 2.03735
27 4KVL PLM 2.03735
28 2XAU ADP 2.03735
29 6FAA ADP 2.03735
30 1RJW ETF 2.0649
31 4KRI SAH 2.07852
32 2YX1 SFG 2.08333
33 3TKY SAH 2.17391
34 3RFV 15L 2.24719
35 3G2O SAM 2.34114
36 3ICT ADP 2.38095
37 1PJS NAD 2.407
38 5A96 GTP 2.40964
39 3G89 SAM 2.40964
40 3GEG NAD 2.42915
41 2VDV SAM 2.43902
42 1UAY ADN 2.47934
43 3VSE SAH 2.51256
44 1BW9 NAD 2.52809
45 5B47 TPP 2.54669
46 1X87 NAD 2.54669
47 5B47 PYR 2.54669
48 1DJN ADP 2.54669
49 1LK7 DER 2.62009
50 5ZI9 FLC 2.69231
51 4X1B MLI 2.71647
52 5U83 ZN8 2.83019
53 6FTB M0E 2.85714
54 3HWW AKG 2.8777
55 1UP7 NAD 2.8777
56 1Y8Q ATP 2.89017
57 6EQS BV8 2.90909
58 2EJU SAH 2.91005
59 3RIY NAD 2.9304
60 1IZC PYR 2.94985
61 5X62 SAH 2.95567
62 1FP1 SAH 2.95699
63 3LCC SAH 2.97872
64 3A25 SAM 2.99003
65 1KYZ SAH 3.0137
66 2BZG SAH 3.01724
67 5TSH ADP 3.06122
68 5TSH ANP 3.06122
69 4RDI ATP 3.125
70 4RDH AMP 3.125
71 4PPF FLC 3.14286
72 2NXE SAM 3.14961
73 4JJF FE9 3.19767
74 1CDO NAD 3.20856
75 4KRG SAH 3.21888
76 2UYQ SAM 3.22581
77 4D79 ATP 3.26087
78 4LC1 GDP 3.2641
79 1KYQ NAD 3.28467
80 5YF1 SFG 3.31492
81 2OG2 MLI 3.34262
82 4YAC NAI 3.367
83 3L9W GSH 3.38983
84 3L9W AMP 3.38983
85 2O1S TDP 3.39559
86 4DDY DN6 3.42205
87 2PT9 S4M 3.42679
88 1QS0 TDP 3.4398
89 3CBG SAH 3.44828
90 2FK8 SAM 3.45912
91 1G60 SAM 3.46154
92 5E72 SAM 3.46821
93 3OJO NAD 3.48028
94 5XJ7 87O 3.48259
95 4N14 WR7 3.50318
96 3VC1 SAH 3.52564
97 1I1N SAH 3.53982
98 4C4A SAH 3.56537
99 4B2D SER 3.64964
100 5WP5 SAH 3.66599
101 4II2 ATP 3.68098
102 4A6D SAM 3.68272
103 2VVG ADP 3.71429
104 3KLL MAL 3.73514
105 1OBB NAD 3.75
106 1G55 SAH 3.79009
107 4DMG SAM 3.81679
108 1WG8 SAM 3.85965
109 5WP4 SAH 3.86965
110 2I7C AAT 3.88693
111 2JHP SAH 3.90492
112 2EFJ SAH 3.90625
113 1LVL NAD 3.93013
114 5DNK SAH 3.97112
115 5HJM MTA 3.97727
116 5ZW3 SAH 4
117 1T5C ADP 4.01146
118 1P1C SAH 4.0201
119 3LST SAH 4.02299
120 1YC5 NCA 4.06504
121 4BUZ NAD 4.06504
122 4BUZ OCZ 4.06504
123 4BUZ OAD 4.06504
124 3WV8 ATP 4.12844
125 3OFK SAH 4.16667
126 1L1E SAH 4.18118
127 3BXO SAM 4.1841
128 1GOJ ADP 4.22535
129 4PFT MAB 4.22794
130 6BQ6 TER 4.22961
131 3BGD SAH 4.23077
132 1JG3 ADN 4.25532
133 6HOY AR6 4.30464
134 6HOY TSN 4.30464
135 5KVA SAM 4.31655
136 3TKA SAM 4.32277
137 1O97 FAD 4.375
138 1O97 AMP 4.375
139 3ZG6 APR 4.39189
140 1V59 NAD 4.39331
141 4QTU SAM 4.44444
142 2JJQ SAH 4.47059
143 4NZ6 DGL 4.47284
144 3U31 NAD 4.48276
145 1XDS SAM 4.54545
146 1QZZ SAM 4.54545
147 4L2I FAD 4.56274
148 1NJR XYL 4.57746
149 5XNC MTA 4.58221
150 3B9Q MLI 4.63576
151 4OBW SAM 4.66926
152 3FGZ BEF 4.6875
153 5ESO TDP 4.70383
154 5ESO ISC 4.70383
155 6FDF SAH 4.79042
156 2YVK MRU 4.81283
157 5JGL SAM 4.84429
158 1R18 SAH 4.84582
159 1C3X 8IG 4.88722
160 5B48 TDN 4.91803
161 3ABI NAD 4.93151
162 3DUW SAH 4.93274
163 5A3B APR 4.9505
164 5FA8 SAM 4.96894
165 3C3Y SAH 5.06329
166 1S7G NAD 5.13834
167 1S7G APR 5.13834
168 4RL4 PPV 5.18868
169 3T7S SAM 5.22388
170 2O07 MTA 5.26316
171 2O07 SPD 5.26316
172 2OFW ADX 5.28846
173 3GCZ SAM 5.31915
174 1ZPD DPX 5.45775
175 1GXU 2HP 5.49451
176 3EXH TPP 5.49738
177 1EJ0 SAM 5.55556
178 2HMT NAI 5.55556
179 2NGR GDP 5.55556
180 1IHU AF3 5.60272
181 5BW4 SAM 5.61798
182 4BQS ADP 5.68182
183 4AZW SAM 5.73248
184 2OZL TPP 5.75342
185 5ZZ6 ADP 5.76923
186 2AOT SAH 5.82192
187 4KIB SAH 5.88235
188 3H2B SAH 5.91133
189 2X7J TPP 5.94228
190 3AHC TPP 5.94228
191 1OLS TDP 6
192 3A4M ADP 6.15385
193 3DVA TPW 6.15385
194 3GDH SAH 6.22407
195 4Y9D NAI 6.22951
196 3GWZ SAH 6.23306
197 1DL5 SAH 6.30915
198 5MGZ SAH 6.35593
199 4KXQ APR 6.40569
200 5JVB 2PO 6.42857
201 2AWN ADP 6.56168
202 1PNO NAP 6.66667
203 3H4S ADP 6.66667
204 5D4V SAH 6.71642
205 1PL6 NAD 6.74157
206 3GRU AMP 6.77966
207 3DXY SAM 6.88073
208 1FP6 ADP 6.92042
209 2FKA BEF 6.97674
210 3EGI ADP 7.28155
211 1ZGA SAH 7.28291
212 1L3I SAH 7.29167
213 4I5I NAD 7.31707
214 5OJ7 AR6 7.34266
215 5L95 AMP 7.5
216 2BZ1 TAU 7.65306
217 3ITJ CIT 7.69231
218 1NV8 SAM 7.74648
219 1NV8 MEQ 7.74648
220 3W5J GDP 7.84314
221 2HNK SAH 7.94979
222 5N5D SAM 7.9646
223 1N07 ADP 7.97546
224 1M7G AV2 8.05687
225 5O2J 2PO 8.05861
226 2OOR TXP 8.07292
227 4FZV SAM 8.07799
228 3A27 SAM 8.08823
229 2DPM SAM 8.09859
230 1DJL NAP 8.21256
231 5E5U MLT 8.54271
232 5EXE 5SR 8.59873
233 1QAN SAH 8.60656
234 2CDU ADP 8.62832
235 1APZ ASP 8.64198
236 1WY7 SAH 8.69565
237 2ZIF SAM 8.75421
238 2UVO NDG 8.77193
239 2UVO NAG 8.77193
240 4AML GYU 8.77193
241 5BQ5 ADP BEF 8.99471
242 5NM7 GLY 9.02256
243 1G8K MGD 9.02256
244 1JQ3 AAT 9.12162
245 4IF4 BEF 9.13461
246 1D4O NAP 9.23913
247 5JE8 NAD 9.27152
248 2VT3 ATP 9.30233
249 2Y65 ADP 9.31507
250 1UMD TDP COI 9.53679
251 4YMH SAH 9.58333
252 6ECT SAM 9.65732
253 1K7V NAG GAL BGC 9.67742
254 3VYW SAM 9.74026
255 1EFV AMP 9.80392
256 1EFV FAD 9.80392
257 1IM8 SAI 9.83607
258 3V1S 0LH 9.93789
259 4IWN GEK 10.0437
260 1N2X SAM 10.299
261 3I53 SAH 10.8434
262 3MAG SAH 12.0521
263 2PWY SAH 12.4031
264 3MCT SAH 12.4579
265 4CQM NAP 12.6437
266 2QQF A1R 12.6623
267 2OD9 A1R NCA 12.6623
268 1M2K APR 12.8514
269 1SZD APR 13.1313
270 5GM1 SAH 13.1313
271 3FUU ADN 13.2841
272 3JWH SAH 13.3641
273 1LSS NAD 13.5714
274 6F5Z SAH 13.8528
275 4POO SAM 14.5
276 4PIO AVI 14.5511
277 4PIO SAH 14.5511
278 2PEZ DAT 15.0838
279 2VOH CIT 15.3846
280 1L5Y BEF 18.0645
281 1ZQ9 SAM 18.2456
282 5BSZ SAH 19.2
283 5FA5 MTA 20
284 2XKO AKG 20.2247
285 1W85 TDP 24.4898
286 2VK4 TPP 33.3925
287 1QPB PYM 33.5702
288 1QPB TPP 33.5702
289 2KIN ADP 34
290 2C31 TZD 36.9718
291 2C31 ADP 36.9718
292 2VBF TPP 37.0175
293 2Q28 TPP 37.766
294 2Q28 ADP 37.766
295 2NXW TPP 38.2301
296 1YBH P22 38.7097
297 1YBH FAD 38.7097
298 4D5G FAD 38.7097
299 4D5G TPP 38.7097
300 2IHT TPP 41.0122
301 1UPA TPP 41.0122
302 2IHU TP9 41.8848
303 3FSJ D7K 42.2348
304 3IAE D7K 42.6316
305 6DEN TP9 42.9542
306 6DEN G8A 42.9542
307 6DEN FAD 42.9542
308 4RJK TPP 43.0823
309 4RJK TDL 43.0823
310 2UZ1 TPP 43.1616
311 1T9D P22 43.9728
312 1T9D FAD 43.9728
313 5WKC FAD 43.9728
314 1T9D 1MM 43.9728
315 1T9D P25 43.9728
316 5WKC TP9 43.9728
317 5WKC AUJ 43.9728
318 1T9D PYD 43.9728
319 1OZH HE3 44.8763
320 3EYA FAD 47.9053
321 3EYA TDP 47.9053
Pocket No.: 6; Query (leader) PDB : 1V5F; Ligand: TPP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1v5f.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1V5F; Ligand: TPP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1v5f.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1V5F; Ligand: TPP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1v5f.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
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