Receptor
PDB id Resolution Class Description Source Keywords
1UZD 2.4 Å EC: 4.1.1.39 CHLAMYDOMONAS,SPINACH CHIMERIC RUBISCO CHLAMYDOMONAS REINHARDTII LYASE RUBISCO PHOTOSYNTHESIS CARBON DIOXIDE FIXATION PHOTORESPIRATION OXIDOREDUCTASE MONOOXYGENASE CHLOROPLAST TRANSIT PEPTIDE MULTIGENE FAMILY
Ref.: CHIMERIC SMALL SUBUNITS INFLUENCE CATALYSIS WITHOUT CAUSING GLOBAL CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURE OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE BIOCHEMISTRY V. 44 9851 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CAP A:1477;
B:1477;
E:1477;
H:1477;
K:1477;
O:1477;
R:1477;
V:1477;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
356.115 C6 H14 O13 P2 C([C@...
EDO A:1478;
A:1479;
A:1480;
A:1481;
A:1482;
A:1483;
B:1478;
B:1479;
B:1480;
B:1481;
B:1482;
C:1135;
C:1136;
E:1478;
E:1479;
E:1480;
E:1481;
E:1482;
F:1135;
H:1478;
H:1479;
H:1480;
H:1481;
I:1135;
J:1135;
K:1478;
K:1479;
K:1480;
K:1481;
K:1482;
M:1135;
O:1478;
O:1479;
O:1480;
O:1481;
O:1482;
O:1483;
P:1135;
R:1478;
R:1479;
R:1480;
R:1481;
R:1482;
R:1483;
R:1484;
T:1135;
T:1136;
V:1478;
V:1479;
V:1480;
V:1481;
V:1482;
V:1483;
W:1135;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
MG A:1476;
B:1476;
E:1476;
H:1476;
K:1476;
O:1476;
R:1476;
V:1476;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1UZD 2.4 Å EC: 4.1.1.39 CHLAMYDOMONAS,SPINACH CHIMERIC RUBISCO CHLAMYDOMONAS REINHARDTII LYASE RUBISCO PHOTOSYNTHESIS CARBON DIOXIDE FIXATION PHOTORESPIRATION OXIDOREDUCTASE MONOOXYGENASE CHLOROPLAST TRANSIT PEPTIDE MULTIGENE FAMILY
Ref.: CHIMERIC SMALL SUBUNITS INFLUENCE CATALYSIS WITHOUT CAUSING GLOBAL CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURE OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE BIOCHEMISTRY V. 44 9851 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 1UZD - CAP C6 H14 O13 P2 C([C@H]([C....
70% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 1UWA - CAP C6 H14 O13 P2 C([C@H]([C....
2 1UW9 - CAP C6 H14 O13 P2 C([C@H]([C....
3 1AA1 - 3PG C3 H7 O7 P C([C@H](C(....
4 1RCO - XDP C5 H14 O12 P2 C([C@H]([C....
5 1RBO Kd = 0.19 pM CAP C6 H14 O13 P2 C([C@H]([C....
6 1RXO - RUB C5 H12 O11 P2 C([C@H]([C....
7 1UPP - CAP C6 H14 O13 P2 C([C@H]([C....
8 1RCX - RUB C5 H12 O11 P2 C([C@H]([C....
9 1UZD - CAP C6 H14 O13 P2 C([C@H]([C....
10 1UZH - CAP C6 H14 O13 P2 C([C@H]([C....
50% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 1UWA - CAP C6 H14 O13 P2 C([C@H]([C....
2 1UW9 - CAP C6 H14 O13 P2 C([C@H]([C....
3 8RUC - CAP C6 H14 O13 P2 C([C@H]([C....
4 1UPM - CAP C6 H14 O13 P2 C([C@H]([C....
5 1AA1 - 3PG C3 H7 O7 P C([C@H](C(....
6 1RCO - XDP C5 H14 O12 P2 C([C@H]([C....
7 1RBO Kd = 0.19 pM CAP C6 H14 O13 P2 C([C@H]([C....
8 1RXO - RUB C5 H12 O11 P2 C([C@H]([C....
9 1UPP - CAP C6 H14 O13 P2 C([C@H]([C....
10 1RCX - RUB C5 H12 O11 P2 C([C@H]([C....
11 1UZD - CAP C6 H14 O13 P2 C([C@H]([C....
12 1UZH - CAP C6 H14 O13 P2 C([C@H]([C....
13 1RSC - XBP C5 H12 O11 P2 C([C@H]([C....
14 1RBL - CAP C6 H14 O13 P2 C([C@H]([C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CAP; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 CAP 1 1
2 XDP 0.543478 0.945946
3 DER 0.434783 0.918919
4 DEZ 0.434783 0.918919
5 4TP 0.416667 0.772727
6 PA5 0.408163 0.918919
7 R10 0.408163 0.918919
8 HG3 0.404762 0.810811
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1UZD; Ligand: CAP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1uzd.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1UZD; Ligand: CAP; Similar sites found: 67
This union binding pocket(no: 2) in the query (biounit: 1uzd.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4YMZ 13P 0.006986 0.42761 3.18725
2 1SW0 PGA 0.001921 0.44547 3.22581
3 1OVD FMN 0.004658 0.42432 3.73134
4 4I9A NCN 0.003022 0.42348 3.73134
5 4PTN GXV 0.01272 0.4196 3.73134
6 4M00 SUC 0.0337 0.40608 3.73134
7 1VPD TLA 0.01808 0.40502 3.73134
8 2YPI PGA 0.003196 0.43964 4.45344
9 1W3T 3GR 0.001387 0.45347 4.47761
10 4AF0 IMP 0.001539 0.42671 4.47761
11 5EYW PGA 0.008874 0.42241 4.47761
12 2C6Q IMP 0.002326 0.40209 4.47761
13 2WZF BGC 0.02733 0.40169 4.47761
14 3GLC R5P 0.01374 0.40474 5.08475
15 3CTL S6P 0.005822 0.40393 5.19481
16 1QDS PGA 0.002288 0.44671 5.22388
17 4UWH JXM 0.004012 0.42594 5.22388
18 4NRT 2NG 0.01044 0.4175 5.22388
19 2Q89 6CS 0.02325 0.40135 5.22388
20 1VKF CIT 0.01901 0.41211 5.31915
21 3MI2 PFU 0.009391 0.42099 5.37634
22 3MJY IJZ 0.007757 0.40989 5.49133
23 4IGH ORO 0.02189 0.41352 5.64516
24 4IGH FMN 0.02189 0.41352 5.64516
25 4IGH 1EA 0.02189 0.41352 5.64516
26 1EIX BMQ 0.00908 0.40221 5.68421
27 1M5W DXP 0.02865 0.40082 5.76132
28 2NSX IFM 0.004124 0.42968 5.97015
29 3B0P FMN 0.003455 0.42482 5.97015
30 3B9O FMN 0.009057 0.40226 5.97015
31 1TRD PGH 0.004916 0.42605 6
32 3AI3 SOE 0.01888 0.41022 6.08365
33 4NAE 1GP 0.0001729 0.52352 6.22222
34 2Q8Z NUP 0.001921 0.41036 6.43275
35 4BI7 PGA 0.005171 0.43416 6.71642
36 4HKP 16B 0.001517 0.4327 6.71642
37 4UTU LRY 0.002958 0.4321 6.71642
38 5A5W GUO 0.003836 0.43131 6.71642
39 2QCD U5P 0.001907 0.42458 6.71642
40 1DQX BMP 0.002033 0.4198 6.71642
41 4HKP TKW 0.002567 0.41057 6.71642
42 2FLI DX5 0.005182 0.40283 6.71642
43 1O4T OXL 0.01269 0.41502 6.76692
44 2BTM PGA 0.007922 0.42488 7.46269
45 2F6U CIT 0.01064 0.42308 7.46269
46 4EWN 0VR 0.008438 0.40717 7.46269
47 3VKC FPQ 0.004857 0.40401 8.04196
48 3OVR 5SP 0.0009172 0.42848 8.20895
49 4WZH FMN 0.004196 0.4133 8.20895
50 3WIR BGC 0.02375 0.40602 8.20895
51 3EXS 5RP 0.0004602 0.48065 8.95522
52 2ZZV LAC 0.02793 0.40211 8.95522
53 4CFU 2WC 0.01549 0.40224 9.16031
54 4BCN T9N 0.01399 0.40067 9.16031
55 2FFC U5P 0.007841 0.40165 9.70149
56 5VIT MLI 0.01274 0.40211 10.101
57 1Q6O LG6 0.0004484 0.42758 11.194
58 2BLE 5GP 0.006266 0.40874 11.194
59 3QH2 3NM 0.002537 0.4551 11.3122
60 4JEJ 1GP 0.0006264 0.46861 11.4754
61 3BJE URA 0.0255 0.40179 12.6866
62 3T7V MD0 0.007406 0.43119 14.1791
63 4AQ4 G3P 0.02677 0.40235 16.4179
64 4ORM ORO 0.0186 0.41629 23.1343
65 4ORM FMN 0.0186 0.41629 23.1343
66 4ORM 2V6 0.0186 0.41629 23.1343
67 2OEM 1AE 0.000002781 0.49853 40.9201
Pocket No.: 3; Query (leader) PDB : 1UZD; Ligand: CAP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1uzd.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1UZD; Ligand: CAP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1uzd.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1UZD; Ligand: CAP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1uzd.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1UZD; Ligand: CAP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1uzd.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1UZD; Ligand: CAP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1uzd.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1UZD; Ligand: CAP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1uzd.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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