Receptor
PDB id Resolution Class Description Source Keywords
1UHB 2.15 Å EC: 3.4.21.4 CRYSTAL STRUCTURE OF PORCINE ALPHA TRYPSIN BOUND WITH AUTO CATALYTICALY PRODUCED NATIVE PEPTIDE AT 2.15 A RESOLUTION SUS SCROFA SERINE PROTEASE HYDROLASE PEPTIDE TRYPSIN COMPLEX
Ref.: TRYPSIN ACTIVITY REDUCED BY AN AUTOCATALYTICALLY PR NONAPEPTIDE. J.BIOMOL.STRUCT.DYN. V. 21 737 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT P:390;
 Invalid;
 none;
 submit data
59.044 C2 H3 O2 CC(=O...
CA A:256;
 Part of Protein;
 none;
 submit data
40.078 Ca [Ca+2...
GLY LYS ASP SER CYS GLN GLY ASP SER P:1;
 Valid;
 none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5XWA 1.9 Å EC: 3.4.21.4 CRYSTAL STRUCTURE OF PORCINE PANCREATIC TRYPSIN WITH TRIPEPT INHIBITOR, PRY, AT PH 10 SUS SCROFA PROTEASE INHIBITOR COMPLEX HYDROLASE HYDROLASE-HYDROLASEINHIBITOR COMPLEX
Ref.: TRIPEPTIDES DERIVED FROM REACTIVE CENTRE LOOP OF PO II PROTEASE INHIBITORS PREFERENTIALLY INHIBIT MIDGU PROTEASES OF HELICOVERPA ARMIGERA. INSECT BIOCHEM. MOL. BIOL. V. 95 17 2018
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 5XW8 - ACE PRO ARG ASN n/a n/a
2 5XW9 - ACE PRO ARG TYR n/a n/a
3 5XWA - ACE PRO ARG TYR n/a n/a
4 1UHB - GLY LYS ASP SER CYS GLN GLY ASP SER n/a n/a
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 5XW8 - ACE PRO ARG ASN n/a n/a
2 5XW9 - ACE PRO ARG TYR n/a n/a
3 5XWA - ACE PRO ARG TYR n/a n/a
4 1UHB - GLY LYS ASP SER CYS GLN GLY ASP SER n/a n/a
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1GG6 - APL C12 H14 F3 N O3 CC(=O)N[C@....
2 5XW8 - ACE PRO ARG ASN n/a n/a
3 5XW9 - ACE PRO ARG TYR n/a n/a
4 5XWA - ACE PRO ARG TYR n/a n/a
5 1UHB - GLY LYS ASP SER CYS GLN GLY ASP SER n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GLY LYS ASP SER CYS GLN GLY ASP SER; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: GLY LYS ASP SER CYS GLN GLY ASP SER; Similar ligands found: 1
No: Ligand Similarity coefficient
1 GLY LYS ASP SER CYS GLN GLY ASP SER 1.0000
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
Feedback