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Receptor
PDB id Resolution Class Description Source Keywords
1U8X 2.05 Å EC: 3.2.1.122 CRYSTAL STRUCTURE OF GLVA FROM BACILLUS SUBTILIS, A METAL-RE NAD-DEPENDENT 6-PHOSPHO-ALPHA-GLUCOSIDASE BACILLUS SUBTILIS STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE MCSGGLUCOSIDASE NAD-DEPENDENT MIDWEST CENTER FOR STRUCTURAL GHYDROLASE
Ref.: NOVEL CATALYTIC MECHANISM OF GLYCOSIDE HYDROLYSIS B THE STRUCTURE OF AN NAD(+)/MN(2+)-DEPENDENT PHOSPHO-ALPHA-GLUCOSIDASE FROM BACILLUS SUBTILIS. STRUCTURE V. 12 1619 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
G6P X:902;
Valid;
none;
submit data
260.136 C6 H13 O9 P C([C@...
MN X:700;
Part of Protein;
none;
submit data
54.938 Mn [Mn+2...
NAD X:900;
Valid;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1U8X 2.05 Å EC: 3.2.1.122 CRYSTAL STRUCTURE OF GLVA FROM BACILLUS SUBTILIS, A METAL-RE NAD-DEPENDENT 6-PHOSPHO-ALPHA-GLUCOSIDASE BACILLUS SUBTILIS STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE MCSGGLUCOSIDASE NAD-DEPENDENT MIDWEST CENTER FOR STRUCTURAL GHYDROLASE
Ref.: NOVEL CATALYTIC MECHANISM OF GLYCOSIDE HYDROLYSIS B THE STRUCTURE OF AN NAD(+)/MN(2+)-DEPENDENT PHOSPHO-ALPHA-GLUCOSIDASE FROM BACILLUS SUBTILIS. STRUCTURE V. 12 1619 2004
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1U8X - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1U8X - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1U8X - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: G6P; Similar ligands found: 61
No: Ligand ECFP6 Tc MDL keys Tc
1 M6D 1 1
2 BG6 1 1
3 G6P 1 1
4 A6P 1 1
5 BGP 1 1
6 M6P 1 1
7 RP5 0.8 0.902439
8 ABF 0.8 0.902439
9 HSX 0.8 0.902439
10 AHG 0.621622 0.795455
11 GLP 0.590909 0.829787
12 4R1 0.590909 0.829787
13 50A 0.571429 0.8
14 RF5 0.571429 0.8
15 16G 0.55102 0.75
16 4QY 0.55102 0.75
17 BMX 0.55102 0.75
18 EMZ 0.55 0.636364
19 GRF 0.547619 0.692308
20 NNG 0.530612 0.75
21 XYT 0.527273 0.906977
22 1FT 0.517857 0.847826
23 FDQ 0.511111 0.777778
24 G16 0.5 0.951219
25 PRP 0.5 0.880952
26 RI2 0.5 0.857143
27 T6P 0.470588 0.906977
28 D6G 0.468085 0.951219
29 P3M 0.466667 0.906977
30 GIV 0.461538 0.675
31 GLC 0.461538 0.675
32 ALL 0.461538 0.675
33 GXL 0.461538 0.675
34 GAL 0.461538 0.675
35 BMA 0.461538 0.675
36 BGC 0.461538 0.675
37 WOO 0.461538 0.675
38 GLA 0.461538 0.675
39 MAN 0.461538 0.675
40 LAK 0.45098 0.674419
41 GLA BGC 0.45098 0.674419
42 MAN MAN 0.45098 0.674419
43 GLC GLC 0.45098 0.674419
44 BGC GLC 0.45098 0.674419
45 MAN BMA 0.45098 0.674419
46 GAL GLC 0.45098 0.674419
47 BMA MAN 0.45098 0.674419
48 BMA GLA 0.45098 0.674419
49 GLA GLC 0.45098 0.674419
50 GLC BGC 0.45098 0.674419
51 GLA BMA 0.45098 0.674419
52 MLB 0.45098 0.674419
53 BGC GLA 0.45098 0.674419
54 GAL GAL 0.45098 0.674419
55 N 0.444444 0.777778
56 PPC 0.442308 0.822222
57 GLC GLC GLC GLC GLC BGC 0.433962 0.674419
58 GLC GLC GLC 0.433962 0.674419
59 MAN MAN MAN 0.433962 0.674419
60 BMA MAN MAN 0.433962 0.674419
61 GLC GLC GLC GLC BGC 0.433962 0.674419
Ligand no: 2; Ligand: NAD; Similar ligands found: 230
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NHD 0.821429 0.972222
3 NAP 0.811966 0.986111
4 NFD 0.791304 0.946667
5 NXX 0.765766 0.972603
6 DND 0.765766 0.972603
7 AMP NAD 0.74359 0.972222
8 ZID 0.737705 0.986111
9 NAQ 0.729508 0.934211
10 NAE 0.721311 0.959459
11 NA0 0.712 0.972603
12 TAP 0.704 0.921053
13 NDE 0.689922 0.972603
14 NAJ 0.683333 0.972222
15 NDC 0.679389 0.934211
16 NDO 0.674603 0.958904
17 N01 0.656 0.972222
18 CNA 0.642276 0.972603
19 NBP 0.621212 0.922078
20 8ID 0.609756 0.922078
21 A2D 0.576923 0.958333
22 ADP 0.575472 0.931507
23 NGD 0.574803 0.922078
24 BA3 0.566038 0.958333
25 M33 0.564815 0.918919
26 ADP PO3 0.563636 0.957747
27 B4P 0.560748 0.958333
28 AP5 0.560748 0.958333
29 AN2 0.555556 0.918919
30 AT4 0.555556 0.894737
31 GAP 0.553571 0.932432
32 OOB 0.551724 0.972222
33 CA0 0.550459 0.932432
34 9JJ 0.546053 0.898734
35 HEJ 0.545455 0.931507
36 ACP 0.545455 0.906667
37 ATP 0.545455 0.931507
38 DQV 0.544 0.972222
39 ADP ALF 0.54386 0.883117
40 ALF ADP 0.54386 0.883117
41 DAL AMP 0.543103 0.945205
42 APR 0.540541 0.931507
43 AQP 0.540541 0.931507
44 AR6 0.540541 0.931507
45 5FA 0.540541 0.931507
46 ADP VO4 0.53913 0.945205
47 VO4 ADP 0.53913 0.945205
48 AD9 0.535714 0.906667
49 SAP 0.535714 0.883117
50 AGS 0.535714 0.883117
51 WAQ 0.533333 0.896104
52 ABM 0.53271 0.905405
53 DLL 0.529412 0.972222
54 00A 0.529412 0.921053
55 ACQ 0.526316 0.906667
56 NJP 0.526316 0.959459
57 ANP 0.526316 0.906667
58 OAD 0.525 0.932432
59 ADX 0.522523 0.839506
60 5AL 0.521739 0.945205
61 A1R 0.521008 0.871795
62 9SN 0.520325 0.909091
63 A 0.518868 0.930556
64 AMP 0.518868 0.930556
65 50T 0.517857 0.893333
66 ATF 0.517241 0.894737
67 1ZZ 0.516393 0.851852
68 3OD 0.516393 0.932432
69 SON 0.513514 0.92
70 PRX 0.513274 0.881579
71 6YZ 0.512821 0.906667
72 SRP 0.512821 0.92
73 9X8 0.512397 0.883117
74 ADP BMA 0.512397 0.932432
75 3UK 0.512397 0.958904
76 MYR AMP 0.512195 0.851852
77 NAJ PZO 0.510949 0.909091
78 NMN 0.509434 0.875
79 A3R 0.508333 0.871795
80 B5V 0.508197 0.945946
81 AMP DBH 0.507937 0.906667
82 A22 0.504202 0.945205
83 ATP A A A 0.504 0.971831
84 B5M 0.504 0.933333
85 FA5 0.504 0.945946
86 8QN 0.5 0.945205
87 NAX 0.496183 0.886076
88 TYR AMP 0.496063 0.933333
89 PR8 0.495935 0.8625
90 AMO 0.495868 0.92
91 ADQ 0.495868 0.932432
92 4AD 0.495868 0.933333
93 PAJ 0.495868 0.873418
94 A12 0.495495 0.894737
95 AP2 0.495495 0.894737
96 AHZ 0.492308 0.851852
97 YAP 0.492063 0.933333
98 FYA 0.491935 0.918919
99 AHX 0.491803 0.884615
100 4UU 0.488372 0.933333
101 5SV 0.487603 0.8375
102 TAT 0.487179 0.894737
103 T99 0.487179 0.894737
104 APC 0.486957 0.894737
105 SRA 0.486239 0.881579
106 6V0 0.484848 0.909091
107 NAI 0.484848 0.921053
108 GTA 0.484615 0.898734
109 A A 0.483871 0.958333
110 LAD 0.483871 0.873418
111 AU1 0.482456 0.906667
112 F2R 0.481752 0.831325
113 OMR 0.481203 0.841463
114 TXE 0.481203 0.921053
115 AF3 ADP 3PG 0.481203 0.873418
116 LAQ 0.480916 0.851852
117 G3A 0.48062 0.909091
118 B5Y 0.480315 0.933333
119 NB8 0.48 0.884615
120 TXA 0.48 0.92
121 BIS 0.48 0.871795
122 ME8 0.48 0.851852
123 PTJ 0.48 0.884615
124 139 0.477941 0.886076
125 LPA AMP 0.477273 0.851852
126 AFH 0.476923 0.873418
127 AR6 AR6 0.476923 0.958333
128 G5P 0.476923 0.909091
129 ARG AMP 0.476923 0.841463
130 25L 0.47619 0.945205
131 NAJ PYZ 0.475524 0.864198
132 25A 0.47541 0.958333
133 9ZA 0.47541 0.896104
134 9ZD 0.47541 0.896104
135 DZD 0.47482 0.897436
136 TXD 0.473684 0.921053
137 4UV 0.472868 0.933333
138 TYM 0.470149 0.945946
139 RBY 0.470085 0.894737
140 ADV 0.470085 0.894737
141 4TA 0.467626 0.864198
142 48N 0.466165 0.884615
143 XAH 0.465116 0.851852
144 4UW 0.462687 0.897436
145 M24 0.461538 0.886076
146 80F 0.460993 0.853659
147 IOT 0.459854 0.821429
148 T5A 0.456522 0.853659
149 EAD 0.455782 0.886076
150 MAP 0.455285 0.883117
151 GA7 0.454545 0.894737
152 BT5 0.453901 0.821429
153 A4P 0.452555 0.833333
154 UP5 0.451852 0.933333
155 PAP 0.445378 0.917808
156 4TC 0.445255 0.909091
157 AP0 0.445255 0.884615
158 YLP 0.444444 0.831325
159 P1H 0.443709 0.864198
160 AOC 0.442478 0.810811
161 Z5A 0.439189 0.833333
162 LMS 0.4375 0.817073
163 2A5 0.436975 0.857143
164 A G 0.43662 0.921053
165 G A A A 0.43662 0.909091
166 COD 0.43662 0.802326
167 ADJ 0.435714 0.841463
168 YLB 0.434783 0.831325
169 YLC 0.434783 0.851852
170 U A G G 0.433566 0.921053
171 ATR 0.433333 0.90411
172 7MD 0.432836 0.851852
173 8X1 0.432 0.764045
174 G5A 0.429752 0.790698
175 PO4 PO4 A A A A PO4 0.429688 0.943662
176 TAD 0.42963 0.873418
177 5AS 0.42735 0.770115
178 BTX 0.426573 0.831325
179 YLA 0.425532 0.831325
180 DSZ 0.425197 0.790698
181 NCN 0.424779 0.805556
182 UPA 0.42446 0.921053
183 8PZ 0.424242 0.811765
184 VMS 0.424 0.8
185 54H 0.424 0.8
186 9K8 0.423077 0.744444
187 N0B 0.422819 0.853659
188 6AD 0.422764 0.85
189 AYB 0.422535 0.821429
190 7D3 0.422414 0.844156
191 YLY 0.421769 0.821429
192 TSB 0.420635 0.809524
193 ODP 0.41958 0.922078
194 AV2 0.419355 0.855263
195 FB0 0.419355 0.775281
196 A5A 0.419355 0.819277
197 NNR 0.419048 0.739726
198 A A A 0.418605 0.918919
199 U A 0.417808 0.946667
200 649 0.417266 0.775281
201 NMN AMP PO4 0.416667 0.933333
202 SSA 0.416 0.790698
203 P5A 0.415385 0.755556
204 LSS 0.414062 0.772727
205 A2R 0.412698 0.918919
206 52H 0.412698 0.790698
207 JB6 0.412214 0.896104
208 5N5 0.411215 0.783784
209 YSA 0.410448 0.811765
210 53H 0.409449 0.790698
211 5CA 0.409449 0.790698
212 ITT 0.408333 0.878378
213 7D4 0.408333 0.844156
214 NA7 0.407692 0.894737
215 LEU LMS 0.407692 0.784091
216 5CD 0.407407 0.794521
217 0WD 0.406897 0.909091
218 A3P 0.40678 0.930556
219 HFD 0.406504 0.883117
220 AVV 0.40625 0.860759
221 RAB 0.40566 0.808219
222 XYA 0.40566 0.808219
223 ADN 0.40566 0.808219
224 FDA 0.405063 0.823529
225 GSU 0.40458 0.790698
226 7MC 0.404255 0.831325
227 NSS 0.403101 0.811765
228 6FA 0.402516 0.853659
229 PPS 0.4 0.817073
230 NVA LMS 0.4 0.784091
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1U8X; Ligand: NAD; Similar sites found with APoc: 661
This union binding pocket(no: 1) in the query (biounit: 1u8x.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
1 5Y77 FAD 0.847458
2 4OOE FOM 0.990099
3 4OOE NDP 0.990099
4 5DNK SAH 1.05932
5 1E1M NAP 1.08696
6 1E1M FAD 1.08696
7 1VQW FAD 1.09409
8 5VKT NAP 1.10497
9 1NYT NAP 1.10701
10 1H2B NAJ 1.11421
11 2GV8 FAD 1.11857
12 2GVC FAD 1.11857
13 4FN4 NAD 1.1811
14 1TZJ A3B 1.18343
15 1OMO NAD 1.24224
16 3LAD FAD 1.27119
17 3IHG FAD 1.27119
18 5UAO FAD 1.27119
19 5E9W SAH 1.28205
20 5E8J SAH 1.28205
21 1HYH NAD 1.2945
22 1E3I CXF 1.32979
23 5Y8L HUI 1.35593
24 5Y8L NAD 1.35593
25 1RM0 D6P 1.48305
26 1RM0 NAI 1.48305
27 5J5Z FAD 1.48305
28 1O0S NAI 1.48305
29 2NVK NAP 1.48305
30 4JDR FAD 1.48305
31 1BZL GCG 1.48305
32 1BZL FAD 1.48305
33 1PN0 FAD 1.48305
34 1PN0 IPH 1.48305
35 5D4V SAH 1.49254
36 3BAZ NAP 1.5015
37 6FHO FAD 1.50376
38 1KOL NAD 1.50754
39 1GY8 NAD 1.51134
40 2RAB NAD 1.51188
41 1YKJ PHB 1.52284
42 1YKJ FAD 1.52284
43 1NFQ NAI 1.53846
44 4OPC FDA 1.54525
45 4OPC PGT 1.54525
46 5TC4 NAD 1.58228
47 2VHW NAI 1.59151
48 1N1G BCP 1.63934
49 1HKU NAD 1.67598
50 5LD5 NAD 1.67598
51 1V59 NAD 1.69492
52 6F3N ADN 1.69492
53 6F3N NAD 1.69492
54 4PIV NDP 1.69492
55 1V59 FAD 1.69492
56 4REP FAD 1.69492
57 1D4D FAD 1.69492
58 3B1F NAD 1.72414
59 5KMS NAD 1.7284
60 5KMS FAD 1.7284
61 3H9E NAD 1.7341
62 6F3M NAD 1.73913
63 5G4L NDP 1.74825
64 3QJ4 FAD 1.75439
65 3WLE NAD 1.75953
66 5BUK FAD 1.77778
67 1H6C NDP 1.84758
68 1H6C SIN 1.84758
69 3A06 FOM 1.8617
70 3A06 NDP 1.8617
71 4KP7 NAP 1.87354
72 4KP7 1UQ 1.87354
73 1P31 EPU 1.90678
74 1GPM CIT 1.90678
75 5HSA FAS 1.90678
76 5XWV NDP 1.90678
77 4TXI FAD 1.90678
78 2BRY FAD 1.90678
79 5XWV 8H6 1.90678
80 1U7T TDT 1.91571
81 1WVG APR 1.94986
82 3GFB NAD 2
83 5N6C NAD 2
84 3AXB FAD 2.00893
85 3AXB PRO 2.00893
86 5OJL TXP 2.01342
87 3NUG NAD 2.02429
88 1SQL GUN 2.05479
89 3T31 DCQ 2.0595
90 3T31 FAD 2.0595
91 5OCM NAP 2.06186
92 1RYD NDP 2.06718
93 1UDB NAD 2.07101
94 1UDB UFG 2.07101
95 4GLL NAD 2.07715
96 2C5A NAD 2.11082
97 2C5A GDC 2.11082
98 2FR1 NDP 2.11864
99 4FFG 0U8 2.11864
100 2HQM FAD 2.11864
101 2QA1 FAD 2.11864
102 1B8U NAD 2.12766
103 5G3U ITW 2.12766
104 5G3U FDA 2.12766
105 1B8U OAA 2.12766
106 2RH4 EMO 2.16606
107 1MXH NAP 2.17391
108 1MXH DHF 2.17391
109 5TOW ADN 2.2113
110 5TOW NAI 2.2113
111 1LDN NAD 2.21519
112 1KEW NAD 2.21607
113 1KEW TYD 2.21607
114 1Q0H NDP 2.21675
115 1Q0H FOM 2.21675
116 5Z21 NAI 2.23464
117 1RKX NAD 2.2409
118 1VL8 NAP 2.24719
119 1UXG FUM 2.26537
120 1UXG NAD 2.26537
121 3RKR NAP 2.29008
122 4XYB NDP 2.30179
123 4CNK FAD 2.30179
124 4W6Z 8ID 2.30548
125 1WDK NAD 2.30769
126 1W6U NAP 2.31788
127 1W73 NAP 2.31788
128 6AA8 NAD 2.31788
129 1W8D NAP 2.31788
130 3WQQ IB3 2.33051
131 3WQQ NDP 2.33051
132 6ER9 FAD 2.33051
133 6ER9 NAP 2.33051
134 2ZXI FAD 2.33051
135 2DKH FAD 2.33051
136 2DKH 3HB 2.33051
137 2Z3U CRR 2.35294
138 3MCT SAH 2.3569
139 4GKV NAD 2.38095
140 2EG5 SAH 2.41935
141 1FP1 SAH 2.41935
142 5OOH NAP 2.42718
143 5OOH 9ZZ 2.42718
144 5GSN FAD 2.42826
145 5GSN NAP 2.42826
146 5GSN MMZ 2.42826
147 1V35 NAI 2.43161
148 1NVT NAP 2.43902
149 5Y1G AKB 2.43902
150 5Y1G NAD 2.43902
151 5MIT NAP 2.44648
152 5MIT FAD 2.44648
153 3CH6 NAP 2.44755
154 3CH6 311 2.44755
155 1SC6 NAD 2.47525
156 4TQG NDP 2.47678
157 1UAY ADN 2.47934
158 4TM3 FAD 2.48307
159 2PK3 A2R 2.49221
160 4POO SAM 2.5
161 1GZ6 NAI 2.50784
162 4HXY NDP 2.51142
163 4EIP FAD 2.54237
164 1FEC FAD 2.54237
165 3GGO ENO 2.54777
166 3GGO NAI 2.54777
167 5O9F NAD 2.55682
168 5O9F 9ON 2.55682
169 5H81 NAP 2.57069
170 4D3F NAP 2.58065
171 4FDU IHS 2.58216
172 1N9G NAP 2.59067
173 3VYW SAM 2.5974
174 1NVM NAD 2.6087
175 4X9M FAD 2.63158
176 4NEC SAH 2.65152
177 4RQU NAD 2.66667
178 5ZW3 SAH 2.66667
179 1R6D NAD 2.67062
180 1R6D DAU 2.67062
181 2JHF NAD 2.6738
182 4GNC ASO 2.67559
183 5MLR GRQ 2.6764
184 5MLR NAP 2.6764
185 2YX1 SFG 2.67857
186 5OFW 9TW 2.69058
187 4RSL FAD 2.69663
188 2Q1W NAD 2.7027
189 6CI9 NAP 2.7027
190 6A0S HSE 2.71084
191 6A0S NDP 2.71084
192 1GR0 NAD 2.7248
193 1G6O ADP 2.72727
194 5OVK NDP 2.73438
195 3ABI NAD 2.73973
196 3GD4 NAD 2.73973
197 3LU1 NAD 2.74725
198 3O03 NAP 2.74914
199 1MV8 NAD 2.75229
200 1MUU NAD 2.75229
201 1GZ4 ATP 2.75424
202 1V8B NAD 2.75424
203 3UCL CYH 2.75424
204 3UCL FAD 2.75424
205 3UCL NAP 2.75424
206 4K5S FAD 2.75424
207 4K5S PM0 2.75424
208 2AE2 NAP 2.75424
209 2AE2 PTO 2.75424
210 3H4V DVP 2.77778
211 3H4V NAP 2.77778
212 1VKO NAD 2.7933
213 2B5W NAP 2.80112
214 2EWM NAD 2.81124
215 1BXK NAD 2.8169
216 1EZ4 NAD 2.83019
217 3GEG NAD 2.83401
218 4BV6 FAD 2.83976
219 1SB8 NAD 2.84091
220 1SB8 UD2 2.84091
221 2G5C NAD 2.84698
222 5UR0 NAD 2.86533
223 3LST SAH 2.87356
224 1RYI GOA 2.87958
225 1RYI FAD 2.87958
226 2NPX NAD 2.90828
227 5M67 3D1 2.92276
228 5M67 ADE 2.92276
229 5M67 NAD 2.92276
230 2YVJ NAI 2.94118
231 5XVH NAP 2.94118
232 2YVF NAD 2.94118
233 2YVF FAD 2.94118
234 4MP8 NAD 2.94985
235 4MP8 MLI 2.94985
236 5JAQ NAI 2.95567
237 1F8F NAD 2.96496
238 1H82 GZZ 2.9661
239 1H82 FAD 2.9661
240 1XCL SAH 2.97872
241 4XB2 NDP 2.98507
242 2GSD NAD 2.98507
243 4XB2 HSE 2.98507
244 4MDH NAD 2.99401
245 5YLF BGC 2.99401
246 6FDF SAH 2.99401
247 1IY8 NAD 2.99625
248 5MDH NAD 3.003
249 3CBG SAH 3.01724
250 2CUL FAD 3.01724
251 2XVE FAD 3.01724
252 2XVF FAD 3.01724
253 4PLT OXM 3.02115
254 4PLT NAI 3.02115
255 5DN9 NAD 3.02198
256 2NAD NAD 3.05344
257 4DMG SAM 3.05344
258 2CVQ NDP 3.0581
259 5X68 FAD 3.06905
260 1VM6 NAD 3.07018
261 5N53 8NB 3.07692
262 3JYN NDP 3.07692
263 6AIN FAD 3.11005
264 1KEV NDP 3.1339
265 4CJX NAP 3.1348
266 1X7D NAD 3.14286
267 1X7D ORN 3.14286
268 2O4C NAD 3.15789
269 3ICS ADP 3.17797
270 3ICT ADP 3.17797
271 1W0O SIA 3.17797
272 3ZV6 4HB 3.17797
273 3ZV6 NAD 3.17797
274 1HYE NAP 3.19489
275 5YU3 PRO 3.19767
276 5YU3 NAD 3.19767
277 3G89 SAM 3.21285
278 2Q0L NAP 3.21543
279 2FZW NAD 3.21716
280 1P0F NAP 3.21716
281 1D1T NAD 3.21716
282 1GV0 NAD 3.22581
283 2F1K NAP 3.22581
284 4C2W ANP 3.22581
285 2BGM NAJ 3.23741
286 5EJ2 NAD 3.24675
287 3ITJ CIT 3.25444
288 3MAG SAH 3.25733
289 4MPO AMP 3.26797
290 5AOV NAP 3.27381
291 1EDO NAP 3.27869
292 3D3W NAP 3.27869
293 1PR9 NAP 3.27869
294 1DRV A3D 3.2967
295 1YJQ NAP 3.30033
296 6F9Q NAD 3.30882
297 3E1T FAD 3.32031
298 5T9F TYR 3.32103
299 1PZG A3D 3.32326
300 4USR FAD 3.3241
301 2GCG NDP 3.33333
302 3FPZ AHZ 3.37423
303 1PGP 6PG 3.38983
304 1XSE NDP 3.38983
305 1QO8 FAD 3.38983
306 3CGD NAD 3.38983
307 3CGD FAD 3.38983
308 3CGD COA 3.38983
309 4B2D SER 3.38983
310 6C4M NAP 3.38983
311 3EGI ADP 3.39806
312 3LCC SAH 3.40426
313 1ZEM NAD 3.43511
314 5J60 FAD 3.4375
315 3TWO NDP 3.44828
316 3NJ4 AFX 3.44828
317 3NJ4 NAD 3.44828
318 1E3W NAD 3.44828
319 1ORR NAD 3.45821
320 1E6W NAD 3.46154
321 5A1T NAI 3.51906
322 5A1T OXM 3.51906
323 2NXE SAM 3.54331
324 5BJX NAD 3.55191
325 5BJX UDP 3.55191
326 1KNY KAN 3.55731
327 3V1Y NAD 3.56083
328 1GQ2 NAP 3.60169
329 6BII NAP 3.6036
330 5X9D 80F 3.61842
331 4K26 NDP 3.62319
332 4K26 SFF 3.62319
333 2HK9 ATR 3.63636
334 2HK9 NAP 3.63636
335 1BW9 NAD 3.65169
336 1BXG NAD 3.65169
337 1SOW NAD 3.65854
338 1C1X NAD 3.66197
339 1VI2 NAD 3.66667
340 1HDR NAD 3.68852
341 2Q7V FAD 3.69231
342 1I2B UPG 3.71287
343 1I2B USQ 3.71287
344 1I2B NAD 3.71287
345 3T7S SAM 3.73134
346 6C4T NA7 3.77778
347 2IZ1 ATR 3.79747
348 2NU8 COA 3.81356
349 3OND NAD 3.81356
350 3OND ADN 3.81356
351 4XQC 13D 3.81356
352 4XQC NAD 3.81356
353 5MZI FAD 3.81356
354 5MZI FYK 3.81356
355 2WPF FAD 3.81356
356 2WPF WPF 3.81356
357 5N5D SAM 3.81356
358 1XHC FAD 3.81471
359 4UP3 NDP 3.82166
360 5CAE COA 3.83387
361 5CAE SIN 3.83387
362 5A04 BGC 3.83481
363 5A04 NDP 3.83481
364 2YY7 NAD 3.84615
365 1ZQ9 SAM 3.85965
366 5AHO TLA 3.86905
367 3VPH OXM 3.87097
368 3VPH NAD 3.87097
369 1J49 NAD 3.9039
370 1F8G NAD 3.90625
371 1L7E NAI 3.90625
372 1E6E FAD 3.90625
373 1LDM NAD 3.95137
374 5Z75 NAD 3.97554
375 1CDO NAD 4.01069
376 1U3U NAD 4.01069
377 1U3U BNF 4.01069
378 2ZJ1 NAD 4.02542
379 2ZJ1 ARJ 4.02542
380 5WGR FAD 4.02542
381 5DF1 58X 4.07609
382 5DF1 NAP 4.07609
383 2AOT SAH 4.10959
384 5BW4 SAM 4.11985
385 3WV8 ATP 4.12844
386 1RJW ETF 4.12979
387 2HMT NAI 4.16667
388 3KB6 NAD 4.19162
389 2XOC ADE 4.21456
390 1DLJ UGA 4.22886
391 1DLJ NAI 4.22886
392 2J8Z NAP 4.23729
393 1MO9 KPC 4.23729
394 1MO9 FAD 4.23729
395 5WP5 SAH 4.23729
396 1DJN ADP 4.23729
397 5KOX FAD 4.23729
398 5KOX RFP 4.23729
399 1YB5 NAP 4.2735
400 6GAR FAD 4.29799
401 2DFV NAD 4.32277
402 5EZ7 FAD 4.33673
403 2JDU MFU 4.34783
404 1A5Z NAD 4.38871
405 3CTY FAD 4.38871
406 4WAS NAP 4.3956
407 4WAS COO 4.3956
408 5U5G NAP 4.40678
409 5THQ NDP 4.41176
410 1NM5 NAD 4.4335
411 1EJ0 SAM 4.44444
412 1X87 NAD 4.44915
413 1GTE FAD 4.44915
414 3WMX NAD 4.46927
415 4BVA NDP 4.47761
416 4BVA T3 4.47761
417 4KOA NDP 4.5045
418 2GLX NDP 4.51807
419 3QH2 3NM 4.52489
420 1H5Q NAP 4.5283
421 1Y8Q ATP 4.53125
422 3S5W FAD 4.53564
423 2PZM UDP 4.54545
424 2PZM NAD 4.54545
425 3HAD NAD 4.54545
426 4E5N NAD 4.54545
427 1ZBQ NAD 4.58716
428 1R37 NAD 4.61095
429 3OJO NAD 4.64037
430 2VT3 ATP 4.65116
431 5UAV NDP 4.65839
432 5UAV TFB 4.65839
433 1ZGA SAH 4.66102
434 2Z3Y F2N 4.66102
435 4ZGS NAD 4.66321
436 2V6G NAP 4.67033
437 5GWT NAD 4.67626
438 5GWT SIN 4.67626
439 3Q3C NAD 4.68227
440 1LTH NAD 4.70219
441 5ZZ6 NAD 4.80769
442 5ZZ6 ADP 4.80769
443 1FP2 SAH 4.82955
444 4OM8 NAD 4.85437
445 2RGO FAD 4.87288
446 1E5Q NDP 4.88889
447 2GOO NDG 4.90196
448 4Y9D NAI 4.91803
449 5NMX NAP 4.94118
450 5NMX FAD 4.94118
451 5TWB FAD 4.94186
452 1G0N NDP 4.947
453 1G0N PHH 4.947
454 5K4W THR 4.98442
455 5K4W NAI 4.98442
456 4J4H 1J1 5.01931
457 4J4H NAI 5.01931
458 4JK3 NAD 5.01931
459 5FI3 NAP 5.04202
460 2JHP SAH 5.08475
461 1UWK NAD 5.08475
462 1UWK URO 5.08475
463 3JQ7 NAP 5.08475
464 5JDC NAP 5.08475
465 5K6A NAP 5.08475
466 4PLG NAI 5.08982
467 4PLG OXM 5.08982
468 5O42 9JW 5.10949
469 5O42 BGC 5.10949
470 5O42 NAD 5.10949
471 4IDC 1XX 5.12048
472 4IDC NDP 5.12048
473 2W68 SIA GAL BGC 5.12821
474 1OC2 NAD 5.17241
475 1OC2 TDX 5.17241
476 2OOR NAD 5.17241
477 4RDH AMP 5.20833
478 4RDI ATP 5.20833
479 3VSE SAH 5.27638
480 2A92 NAI 5.29595
481 3UOY NAP 5.29661
482 3UOY FAD 5.29661
483 4YAC NAI 5.38721
484 1V6A TRE 5.42169
485 4RVU NDP 5.42169
486 3OID NDP 5.42636
487 4D79 ATP 5.43478
488 5O4J 9KH 5.47445
489 5O4J PJL 5.47445
490 5O4J SAH 5.47445
491 2XVM SAH 5.52764
492 4J36 1HR 5.54217
493 4J36 FAD 5.54217
494 1LLU NAD 5.55556
495 5EIN NAP 5.55556
496 1O94 ADP 5.625
497 5JE8 NAD 5.62914
498 2C29 DQH 5.63798
499 2C29 NAP 5.63798
500 1Z45 NAD 5.72034
501 4YIW NCD 5.76497
502 4ZRN NAD 5.76923
503 4ZRN UPG 5.76923
504 5YEC ATP 5.88235
505 1RP0 AHZ 5.98592
506 3RFV NAI 5.99251
507 3RFV 15L 5.99251
508 1DSS NAD 6.00601
509 2CDC XYP 6.01093
510 2CDC NAP 6.01093
511 2CDC XYS 6.01093
512 5ZI2 ADP 6.08696
513 5ZI2 NAD 6.08696
514 4XZ3 COA 6.08696
515 4XYM COA 6.08696
516 4FC7 NAP 6.13718
517 4FC7 COA 6.13718
518 2DT5 NAD 6.16114
519 2FKA BEF 6.20155
520 6C4N NAP 6.23608
521 2D5A COA 6.25
522 1O6Z NAD 6.27063
523 3NKS FAD 6.28931
524 2WSB NAD 6.29921
525 2R4J 13P 6.35593
526 2R4J FAD 6.35593
527 4E13 NAD 6.36042
528 4BJZ P3A 6.36792
529 4BJZ FAD 6.36792
530 2HJR APR 6.40244
531 2CDU ADP 6.41593
532 4CQM NAP 6.51341
533 3QWI NAP 6.66667
534 3QWI CUE 6.66667
535 4YMH SAH 6.66667
536 2VZ0 D64 6.71642
537 2VZ0 NAP 6.71642
538 2WD7 NAP 6.71642
539 4J1Q NDP 6.89655
540 4EUE NAI 6.9378
541 5Z20 NAI 6.95652
542 1X14 NAD 6.98254
543 1LVL NAD 6.9869
544 6DNT NAD 6.99153
545 3MYZ TFX 7
546 1PL6 NAD 7.02247
547 1PL6 572 7.02247
548 2Q1S NAI 7.1618
549 4NBU NAI 7.2
550 2GN4 UD1 7.20339
551 2GN4 NDP 7.20339
552 6GAS FAD 7.20339
553 2RGJ FAD 7.21393
554 4II2 ATP 7.22892
555 1C4Q GLA GAL BGC 7.24638
556 5U8U FAD 7.27651
557 5N2I NAP 7.32759
558 1C3V NDP 7.34694
559 2XYQ SAH 7.37705
560 1GUZ NAD 7.41935
561 2DBZ NAP 7.48503
562 4ZVV GN0 7.53012
563 4ZVV NAD 7.53012
564 9LDB NAD 7.53012
565 9LDT NAD 7.53012
566 3LZW NAP 7.53012
567 3LZW FAD 7.53012
568 5Z2F NAP 7.54717
569 1ZK4 NAP 7.56972
570 1PJS NAD 7.62712
571 3O9Z AKG 7.62712
572 3O9Z NAD 7.62712
573 1YQD NAP 7.65027
574 1T26 GBD 7.76398
575 1T26 NAI 7.76398
576 6FC1 MGP 7.8125
577 2F5Z FAD 7.8125
578 5NUF NAD 7.83133
579 5U5N NAD 7.8853
580 3HB5 NAP 7.95107
581 2AG8 NAP 7.98479
582 3AD8 NAD 8.08081
583 2GAG NAD 8.08081
584 1P77 ATR 8.08823
585 5NUE NAD 8.13253
586 4YSX FAD 8.15603
587 3A4V NAD 8.20189
588 3A4V PYR 8.20189
589 1CT9 AMP 8.26271
590 2Y6Q FAD 8.29146
591 2Y6Q I7T 8.29146
592 4CM9 NAP 8.33333
593 4CMI NAP 8.33333
594 4CM4 NAP 8.33333
595 4CLO NAP 8.33333
596 3BMN NAP 8.33333
597 4CLR NAP 8.33333
598 3BMO NAP 8.33333
599 3JQA NAP 8.33333
600 4CME NAP 8.33333
601 3JQF NAP 8.33333
602 3JQG NAP 8.33333
603 3BMQ NAP 8.33333
604 3JQ9 NAP 8.33333
605 3JQ8 NAP 8.33333
606 5JDI NAP 8.33333
607 4CM8 NAP 8.33333
608 3JQB NAP 8.33333
609 5JCJ NAP 8.33333
610 2PV7 NAD 8.38926
611 1KYQ NAD 8.39416
612 4G5H UD7 8.53994
613 4G5H NAP 8.53994
614 2Q46 NAP 8.69565
615 3SJ7 NDP 8.73016
616 2BOI MFU 8.84956
617 3AB1 FAD 8.88889
618 2C5S AMP 8.95884
619 2HYQ MAN MAN 9.01639
620 5ODQ FAD 9.0301
621 1U1I NAD 9.11017
622 1MAI I3P 9.16031
623 5T63 ALA ALA ALA ALA 9.26431
624 6CEP NAD 9.28144
625 6CEP OXM 9.28144
626 6FX2 FUC C4W NAG BMA MAN NAG GAL 9.30233
627 5EES NAP 9.31174
628 2CVZ NDP 9.34256
629 1VJT NAD 9.52381
630 1KYZ SAH 9.58904
631 3L9W AMP 9.68523
632 3L9W GSH 9.68523
633 1WP4 NDP 9.68858
634 1OFL NGK GCD 9.95763
635 6EL3 NAP 9.97375
636 5KKA 6V0 10.2564
637 4KWI 1TJ 10.2662
638 4KWI NAP 10.2662
639 1YKF NAP 10.5114
640 3H8V ATP 10.6164
641 1VL0 NAI 10.6164
642 2EV9 NAP 10.6464
643 2EV9 SKM 10.6464
644 2GZ3 NAP 11.2022
645 3OA2 NAD 11.3208
646 2DC1 NAD 11.4407
647 1J5P NAD 11.4625
648 6BWL NAD 11.5854
649 4YAG NAI 11.7647
650 1LSS NAD 12.1429
651 4NBW NAD 12.8405
652 1VBO MAN MAN MAN 13.4228
653 3H9R TAK 14.6789
654 1SAY PYR 15.5125
655 1DCP HBI 16.3462
656 5L95 AMP 17.5
657 2GDZ NAD 18.3521
658 2BOS GLA GAL GLC 25
659 2BOS GLA GAL GLC NBU 25
660 1OBB NAD 32.4153
661 1UP7 NAD 49.1607
Pocket No.: 2; Query (leader) PDB : 1U8X; Ligand: G6P; Similar sites found with APoc: 10
This union binding pocket(no: 2) in the query (biounit: 1u8x.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 3RUU 37G 1.31004
2 1ZSQ PIB 2.11864
3 3F5K CE5 2.33051
4 1LNM DTX 3.80435
5 1DQX BMP 4.11985
6 4I42 1HA 4.91228
7 5LUN ARG 5.11364
8 4P6C RES 7.56302
9 2VRQ XYP XYP AHR 8.05085
10 1UP7 G6P 49.1607
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