Receptor
PDB id Resolution Class Description Source Keywords
1U2Z 2.2 Å EC: 2.1.1.43 CRYSTAL STRUCTURE OF HISTONE K79 METHYLTRANSFERASE DOT1P FROM YEAST SACCHAROMYCES CEREVISIAE HISTONE METHYLTRANSFERASE NUCLEOSOME
Ref.: STRUCTURE OF THE CONSERVED CORE OF THE YEAST DOT1P, A NUCLEOSOMAL HISTONE H3 LYSINE 79 METHYLTRANSFERASE J.BIOL.CHEM. V. 279 43296 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:801;
B:802;
C:803;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1U2Z 2.2 Å EC: 2.1.1.43 CRYSTAL STRUCTURE OF HISTONE K79 METHYLTRANSFERASE DOT1P FROM YEAST SACCHAROMYCES CEREVISIAE HISTONE METHYLTRANSFERASE NUCLEOSOME
Ref.: STRUCTURE OF THE CONSERVED CORE OF THE YEAST DOT1P, A NUCLEOSOMAL HISTONE H3 LYSINE 79 METHYLTRANSFERASE J.BIOL.CHEM. V. 279 43296 2004
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 36 families.
1 1U2Z - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 26 families.
1 1U2Z - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 22 families.
1 1U2Z - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1U2Z; Ligand: SAH; Similar sites found: 255
This union binding pocket(no: 1) in the query (biounit: 1u2z.bio2) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3NKV GNP 0.003303 0.40373 1.14286
2 1O8B ABF 0.02147 0.40621 1.36986
3 5DNK SAH 0.00001089 0.56452 1.38568
4 3ICT ADP 0.01154 0.41159 1.38568
5 2AJ4 GLA 0.02372 0.40817 1.38568
6 3ICS ADP 0.01535 0.40561 1.38568
7 1PIE GLA 0.013 0.42438 1.43198
8 3A27 SAM 0.00004522 0.50338 1.47059
9 4DCM SAM 0.000122 0.49492 1.6
10 1V59 NAD 0.001504 0.45419 1.61663
11 2JHP SAH 0.001993 0.43512 1.61663
12 1X87 NAD 0.002375 0.4139 1.61663
13 4WS6 WBU 0.01875 0.41235 1.68067
14 3LST SAH 0.0004097 0.47591 1.72414
15 4KRG SAH 0.000005731 0.54914 1.84758
16 4AZT SAM 0.0006264 0.45324 1.84758
17 4C2C ALA ALA ALA 0.002634 0.44801 1.84758
18 5D3U TRP 0.03008 0.40275 1.84758
19 4RLQ 3SK 0.03091 0.40213 1.84758
20 1LVL NAD 0.007213 0.40016 1.84758
21 3LKZ SFG 0.0001082 0.48183 1.86916
22 3TKY SAH 0.0002232 0.44367 1.90217
23 1BH2 GSP 0.001363 0.40424 1.90476
24 2PHT MAN MAN MAN 0.02334 0.40919 1.98413
25 1UKG MMA 0.02228 0.40469 1.98413
26 3M6W SAM 0.0021 0.43823 2.07852
27 2WK1 SAH 0.001149 0.43386 2.12766
28 1KYZ SAH 0.0003034 0.46707 2.19178
29 3T7S SAM 0.0000158 0.52343 2.23881
30 4ONQ SFG 0.00002556 0.51426 2.2409
31 1ZGA SAH 0.000128 0.49961 2.2409
32 5BW4 SAM 0.00006802 0.50094 2.24719
33 5CUQ NSC 0.0002394 0.4678 2.24719
34 1G60 SAM 0.0001453 0.47631 2.30769
35 1XDS SAM 0.0006697 0.4659 2.40642
36 1QZZ SAM 0.001689 0.44704 2.40642
37 3GWZ SAH 0.001284 0.45263 2.43902
38 1KPG SAH 0.001562 0.42468 2.43902
39 3GXO SAH 0.004679 0.42226 2.43902
40 3GCZ SAM 0.00006695 0.49589 2.48227
41 1AZT GSP 0.0009903 0.40938 2.48756
42 1I9G SAM 0.00002541 0.50365 2.5
43 3PT9 SAH 0.000000798 0.58038 2.54042
44 3X0D SAH 0.000003019 0.54869 2.54042
45 2Q28 ADP 0.006851 0.40426 2.54042
46 3LCC SAH 0.000006645 0.54626 2.55319
47 3A4T SFG 0.0000142 0.50908 2.55474
48 5K7U SAM 0.001029 0.44376 2.5788
49 3CBG SAH 0.00000329 0.55995 2.58621
50 1G55 SAH 0.0000006587 0.57713 2.62391
51 2YX1 SFG 0.000006013 0.5619 2.67857
52 5FTW SAH 0.0002379 0.4627 2.73438
53 1XTP SAI 0.000004103 0.54915 2.75591
54 4USR FAD 0.007155 0.40675 2.77008
55 1BZL FAD 0.048 0.40489 2.77136
56 3G89 SAM 0.00003253 0.52751 2.81124
57 1NW5 SAM 0.00002443 0.50962 2.82132
58 5E1M SAH 0.00007609 0.41936 2.90456
59 5E1M PRO PRO LYS ARG ILE ALA 0.00007609 0.41936 2.90456
60 4M37 SAH 0.0000355 0.50264 2.91545
61 4M38 SAH 0.00002697 0.50256 2.91545
62 3FUU ADN 0.00004394 0.49866 2.95203
63 1YXM ADE 0.01841 0.40922 2.9703
64 2PX8 SAH 0.000509 0.4572 2.97398
65 5IL1 SAM 0.0007197 0.45059 3
66 3G2O SAM 0.00007624 0.49342 3.01003
67 3H8V ATP 0.006967 0.40723 3.08219
68 3U31 NAD 0.004583 0.40534 3.10345
69 1TPY SAH 0.001745 0.4227 3.13589
70 3MQ2 SAH 0.0007735 0.45357 3.21101
71 3UVD MB3 0.02544 0.40929 3.22581
72 2PXX SAH 0.0001321 0.47809 3.25581
73 2ZFU SAH 0.0003287 0.45678 3.25581
74 1R6D NAD 0.01632 0.40837 3.2641
75 4N49 SAM 0.0008687 0.43898 3.27103
76 2P41 SAH 0.00007523 0.49367 3.27869
77 1J71 THR ILE THR SER 0.01387 0.42141 3.29341
78 4UCI SAM 0.001109 0.43834 3.37349
79 2XTZ GSP 0.001764 0.4144 3.38983
80 5JGL SAM 0.0004227 0.46534 3.46021
81 4BLW SAH 0.00005675 0.45811 3.46021
82 4BLW AMP 0.00009956 0.4111 3.46021
83 4KRI SAH 0.00005436 0.48973 3.4642
84 1ZMD NAI 0.00255 0.40241 3.4642
85 4RDH AMP 0.008892 0.40943 3.47222
86 2PWY SAH 0.000008771 0.51255 3.48837
87 1WG8 SAM 0.0000872 0.47411 3.50877
88 1NV8 SAM 0.00002575 0.46127 3.52113
89 1NV8 MEQ 0.00008167 0.44911 3.52113
90 1VE3 SAM 0.00002581 0.51407 3.52423
91 3GJX GTP 0.003903 0.40834 3.56164
92 5KVA SAM 0.000005803 0.52514 3.59712
93 2O07 MTA 0.001397 0.40039 3.61842
94 2WA2 SAM 0.000149 0.48566 3.62319
95 3OFK SAH 0.002198 0.41855 3.7037
96 1SQF SAM 0.0002196 0.47324 3.7296
97 3C3Y SAH 0.000126 0.47898 3.79747
98 3SSO SAH 0.00145 0.42959 3.81862
99 1XCL SAH 0.0001974 0.41207 3.82979
100 2UYQ SAM 0.001351 0.47537 3.87097
101 3H2B SAH 0.000007162 0.53255 3.94089
102 3A25 SAM 0.0001226 0.48435 3.98671
103 1FQK ALF 0.0279 0.40358 4
104 3DUW SAH 0.000001351 0.56371 4.03587
105 2XYQ SAH 0.0002026 0.47478 4.09836
106 1DKU AP2 0.02339 0.40344 4.10095
107 3VSE SAH 0.00001993 0.54434 4.15704
108 2HMT NAI 0.001259 0.42856 4.16667
109 3BGD SAH 0.00002598 0.49343 4.23077
110 3BGD PM6 0.00006121 0.45035 4.23077
111 1LSS NAD 0.0009326 0.43768 4.28571
112 5MX4 HPA 0.02714 0.40844 4.29185
113 2EG5 SAH 0.0000445 0.52113 4.30108
114 2BZG SAH 0.00000685 0.53938 4.31034
115 3FRH SAH 0.001789 0.41889 4.34783
116 1F3L SAH 0.000001272 0.55238 4.36137
117 5DM1 SAH 0.00008251 0.40157 4.49438
118 4POO SAM 0.0001343 0.45832 4.5
119 5F8F SFG 0.0002833 0.47815 4.50928
120 1P1C SAH 0.0003066 0.44997 4.52261
121 4PNE SAH 0.0001629 0.4611 4.63576
122 2IMG MLT 0.03249 0.40058 4.63576
123 2PT9 S4M 0.0005349 0.42708 4.6729
124 2EFJ SAH 0.0001012 0.4932 4.6875
125 4LO2 GAL BGC 0.01779 0.40628 4.7619
126 5MPT SAH 0.0004433 0.45984 4.83092
127 4DMG SAM 0.0001657 0.50019 4.83461
128 3HVJ 705 0.000005434 0.44048 4.97738
129 1EJ0 SAM 0.00007387 0.49402 5
130 1DL5 SAH 0.000004437 0.50028 5.04732
131 5UWI GNP 0.003326 0.40012 5.06329
132 1RJD SAM 0.0002985 0.45854 5.08982
133 1FP1 SAH 0.0002186 0.48331 5.10753
134 3VYW SAM 0.000229 0.46339 5.19481
135 4IWN GEK 0.00009481 0.47063 5.24017
136 3GEG NAD 0.00133 0.40031 5.26316
137 3GU3 SAH 0.00002461 0.54711 5.28169
138 3L9W AMP 0.0005941 0.40092 5.32688
139 3BXO SAM 0.00006531 0.51331 5.43933
140 3DXY SAM 0.00001018 0.55834 5.50459
141 5MGZ SAH 0.00009202 0.48485 5.50847
142 5LOG SAH 0.000001861 0.55773 5.5794
143 1N2X SAM 0.00006224 0.47805 5.64784
144 1CS4 GSP 0.001563 0.40661 5.66038
145 5FA5 MTA 0.00000751 0.55044 5.72207
146 5GM1 SAH 0.00009474 0.47065 5.72391
147 1L3I SAH 0.0000374 0.46563 5.72917
148 1IM8 SAI 0.00003442 0.49809 5.7377
149 3TKA SAM 0.0004586 0.45068 5.76369
150 2ZWA SAH 0.0004034 0.449 5.77367
151 3P2E SAH 0.0005215 0.44832 5.77778
152 1UAY ADN 0.002806 0.4367 5.78512
153 4YMH SAH 0.000001207 0.55943 5.83333
154 1BC5 SAH 0.0001557 0.4619 5.94796
155 4X60 SFG 0.00001645 0.41436 6
156 4X60 3XV 0.00001768 0.40953 6
157 5ULP KB1 0.00004831 0.47528 6.00462
158 4GQB 0XU 0.000004954 0.5137 6.10465
159 3O7W SAM 0.0005203 0.47104 6.12245
160 5X62 SAH 0.00001513 0.53023 6.15764
161 1I1N SAH 0.00000439 0.49323 6.19469
162 5FA8 SAM 0.00000001397 0.62599 6.21118
163 4OBW SAM 0.0004133 0.46118 6.22568
164 5HJM MTA 0.0000008394 0.5726 6.25
165 4FZV SAM 0.00007584 0.48363 6.27615
166 5DX8 SFG 0.0000008285 0.5541 6.30372
167 5DXA SFG 0.000001157 0.54822 6.30372
168 5DWQ SFG 0.00000136 0.53609 6.30372
169 5DX1 SFG 0.000001467 0.52516 6.30372
170 5DX0 SFG 0.000001617 0.52382 6.30372
171 3BJE R1P 0.02536 0.40252 6.30372
172 2ZIF SAM 0.00001329 0.521 6.39731
173 3Q87 SAM 0.00008322 0.47293 6.4
174 2VDV SAM 0.00000718 0.55829 6.50407
175 5M58 SAH 0.0001954 0.47077 6.52174
176 2XVM SAH 0.0002103 0.4895 6.53266
177 1NXJ GLV 0.04499 0.40089 6.55738
178 1Y8Q ATP 0.0006498 0.43074 6.6474
179 2HNK SAH 0.000002207 0.54839 6.69456
180 4XUC 43G 0.000003054 0.46446 6.88073
181 4XUC SAM 0.000003054 0.46446 6.88073
182 2FK8 SAM 0.001096 0.43472 6.91824
183 5JJR SAH 0.0001101 0.4864 6.92841
184 1Q0S SAH 0.0000198 0.4906 6.94981
185 5N5D SAM 0.000002222 0.51947 7.07965
186 3OU2 SAH 0.001063 0.41775 7.33945
187 3MB5 SAM 0.00003429 0.48854 7.45098
188 3FZG SAM 0.005104 0.42052 7.5
189 2JJQ SAH 0.0001085 0.50298 7.52941
190 1L1E SAH 0.001112 0.43446 7.66551
191 1QAN SAH 0.00000634 0.52355 7.78689
192 4C4A SAH 0.0000009414 0.57046 7.85219
193 3GDH SAH 0.000002023 0.52916 7.88382
194 1KYQ NAD 0.003561 0.42379 8.0292
195 4Y2H 49K 0.000002729 0.56118 8.23864
196 4Y2H SAH 0.00000299 0.55947 8.23864
197 5THY SAH 0.000603 0.44566 8.39506
198 3LCV SAM 0.0001878 0.4586 8.54093
199 5THZ SAH 0.0005446 0.43985 8.64198
200 1XFF GLU 0.009707 0.41523 8.75
201 3BBH SFG 0.01162 0.40067 8.78049
202 2ODE ALF GDP 0.00124 0.40523 9.21986
203 3EGI ADP 0.00007728 0.53716 9.2233
204 2EJU SAH 0.00001935 0.51957 9.25926
205 2A14 SAH 0.003537 0.41 9.5057
206 3S1S SAH 0.0002749 0.45189 9.69977
207 3DMH SAM 0.00001328 0.51553 9.71129
208 3DMH GMP 0.00003327 0.45954 9.71129
209 1KPH SAH 0.001584 0.42443 9.7561
210 3TLJ SAH 0.00001848 0.49943 9.91957
211 4KIB SAH 0.000009254 0.48253 10.084
212 5E72 SAM 0.00001606 0.50687 10.1156
213 1R18 SAH 0.000005195 0.52713 10.1322
214 4AZW SAM 0.0006809 0.44745 10.1617
215 4NEC SAH 0.00001687 0.53433 10.6061
216 1JG3 ADN 0.00001867 0.52025 10.6236
217 5KOK SAH 0.0000499 0.49628 10.8312
218 4C2G ALA ALA ALA ALA 0.01506 0.41404 11.0855
219 4M73 SAH 0.00005756 0.41425 11.276
220 4M73 M72 0.00006283 0.4087 11.276
221 2AOT SAH 0.0003297 0.47513 11.3014
222 3JWH SAH 0.00001526 0.54992 11.5207
223 2DPM SAM 0.00001313 0.51048 11.6197
224 5NGZ 2BG 0.03288 0.4069 11.6751
225 1Z3C SA8 0.0001516 0.42635 11.745
226 1WY7 SAH 0.00000226 0.54207 12.0773
227 1VBO MAN MAN MAN 0.007038 0.43208 12.0805
228 1VBO MAN 0.01435 0.41495 12.0805
229 3GRU AMP 0.00006885 0.47627 12.5424
230 2NGR AF3 0.01785 0.41463 12.5654
231 3EGV SAH 0.0000122 0.53442 12.5984
232 2NXE SAM 0.00002516 0.51456 12.5984
233 3CX8 GSP 0.0009722 0.41018 12.8079
234 3EVG SAH 0.00008372 0.49163 12.933
235 1ZQ9 SAM 0.0001658 0.4786 12.9825
236 3I53 SAH 0.0003463 0.45582 13.253
237 2HRL SIA GAL SIA BGC NGA CEQ 0.02705 0.40109 13.3858
238 1SQL GUN 0.006553 0.43817 13.6986
239 3VC1 SAH 0.0001625 0.46115 13.7821
240 2RNF UM3 0.01585 0.41732 14.1667
241 4A6D SAM 0.0003348 0.46071 14.4476
242 5E9W SAH 0.00009464 0.51187 14.7436
243 5E8J SAH 0.0001125 0.50223 14.7436
244 1KUJ MMA 0.003514 0.44025 15.0376
245 1ZC3 GNP 0.003896 0.40087 15.0442
246 4R6W SAH 0.00006183 0.42727 15.8915
247 4LWP SAH 0.0000002161 0.54619 16.3043
248 5XVQ SAH 0.004188 0.40389 16.5493
249 5XVK SAH 0.003326 0.40796 17.6056
250 5GVR LMR 0.02747 0.40478 18.3761
251 5JE0 SAH 0.00004951 0.43641 20.6478
252 5JE0 AZ8 0.00004951 0.43641 20.6478
253 4QTU SAM 0.0000386 0.50108 20.6731
254 5L95 AMP 0.003936 0.41464 23.75
255 5H67 ATP 0.01863 0.40154 42.7136
Pocket No.: 2; Query (leader) PDB : 1U2Z; Ligand: SAH; Similar sites found: 12
This union binding pocket(no: 2) in the query (biounit: 1u2z.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3ZFD ANP 0.01143 0.40642 1.7094
2 4LH7 1X8 0.01792 0.41671 1.85759
3 1Q8O MAN MMA 0.03145 0.40198 1.98413
4 4BGB ADP 0.01785 0.4047 3.38462
5 1US5 GLU 0.01661 0.40241 3.82166
6 2XG5 EC5 0.03977 0.40526 4.62428
7 2XG5 EC2 0.03977 0.40526 4.62428
8 1WUU GLA 0.03008 0.40126 4.7619
9 3QPB URA 0.02911 0.40473 4.96454
10 5ARK UMP 0.01851 0.41227 5.97015
11 4ETZ C2E 0.01882 0.40759 7.40741
12 4JX1 CAM 0.007865 0.41429 9.73451
Pocket No.: 3; Query (leader) PDB : 1U2Z; Ligand: SAH; Similar sites found: 4
This union binding pocket(no: 3) in the query (biounit: 1u2z.bio3) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3KVY R2B 0.01609 0.41911 2.26537
2 3KVY URA 0.03573 0.40017 2.26537
3 2XOC ADP 0.03841 0.40186 14.1762
4 5UWR GNP 0.003212 0.40039 40.7407
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