Receptor
PDB id Resolution Class Description Source Keywords
1TYX 1.8 Å NON-ENZYME: TOXIN_VIRAL TITLE OF TAILSPIKE-PROTEIN ENTEROBACTERIA PHAGE P22 COMPLEX VIRAL ADHESION PROTEIN RECEPTOR ENDOGLYCOSIDASE CARBOHYDRATE CELL RECEPTOR RECOGNITION BINDING PROTEIN LIPOPOLYSACCHARIDE
Ref.: CRYSTAL STRUCTURE OF PHAGE P22 TAILSPIKE PROTEIN CO WITH SALMONELLA SP. O-ANTIGEN RECEPTORS. PROC.NATL.ACAD.SCI.USA V. 93 10584 1996
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
RAM MAN GLA ABE RAM MAN GLA ABE B:1;
 Valid;
 none;
 submit data
1219.15 n/a O(C1C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1TYU 1.8 Å NON-ENZYME: TOXIN_VIRAL STRUCTURE OF TAILSPIKE-PROTEIN ENTEROBACTERIA PHAGE P22 COMPLEX VIRAL ADHESION PROTEIN RECEPTOR ENDOGLYCOSIDASE CARBOHYDRATE CELL RECEPTOR RECOGNITION BINDING PROTEIN LIPOPOLYSACCHARIDE
Ref.: CRYSTAL STRUCTURE OF PHAGE P22 TAILSPIKE PROTEIN CO WITH SALMONELLA SP. O-ANTIGEN RECEPTORS. PROC.NATL.ACAD.SCI.USA V. 93 10584 1996
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 64 families.
1 1TYW - RAM MAN GLA TYV RAM GLC MAN GLA TYV n/a n/a
2 1TYU - RAM MAN GLA TYV RAM MAN GLA TYV n/a n/a
3 1TYX - RAM MAN GLA ABE RAM MAN GLA ABE n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 1TYW - RAM MAN GLA TYV RAM GLC MAN GLA TYV n/a n/a
2 1TYU - RAM MAN GLA TYV RAM MAN GLA TYV n/a n/a
3 1TYX - RAM MAN GLA ABE RAM MAN GLA ABE n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 36 families.
1 1TYW - RAM MAN GLA TYV RAM GLC MAN GLA TYV n/a n/a
2 1TYU - RAM MAN GLA TYV RAM MAN GLA TYV n/a n/a
3 1TYX - RAM MAN GLA ABE RAM MAN GLA ABE n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: RAM MAN GLA ABE RAM MAN GLA ABE; Similar ligands found: 22
No: Ligand ECFP6 Tc MDL keys Tc
1 RAM MAN GLA ABE RAM MAN GLA ABE 1 1
2 RAM MAN GLA ABE RAM MAN GLA 0.932584 1
3 RAM MAN GLA TYV RAM GLC MAN GLA TYV 0.857143 1
4 RAM MAN GLA ABE 0.855422 0.973684
5 MMA GLA ABE 0.595506 0.948718
6 MAN GLA ABE 0.543478 0.947368
7 FUC GAL 0.511905 0.868421
8 GLC GAL NAG GAL FUC GLA 0.491071 0.714286
9 BGC GAL FUC GLA 0.489796 0.894737
10 GLC GAL NAG GAL FUC A2G 0.457627 0.705882
11 BGC BGC BGC BGC BGC BGC BGC 0.454545 0.868421
12 GLC BGC BGC BGC 0.454545 0.868421
13 BGC BGC BGC BGC BGC BGC 0.454545 0.868421
14 BGC BGC BGC BGC BGC 0.454545 0.868421
15 BGC BGC BGC 0.454545 0.868421
16 BGC GAL GLA 0.450549 0.868421
17 BGC BGC BGC BGC BGC BGC BGC BGC 0.446809 0.868421
18 BGC GAL FUC A2G 0.419643 0.714286
19 NAG GAL FUC GLA 0.412844 0.714286
20 MAN MAN MAN GLC 0.412371 0.868421
21 BGC FUC GAL NAG GAL 0.405172 0.714286
22 GAL NAG GAL NAG GAL 0.401869 0.686275
Similar Ligands (3D)
Ligand no: 1; Ligand: RAM MAN GLA ABE RAM MAN GLA ABE; Similar ligands found: 1
No: Ligand Similarity coefficient
1 RAM MAN GLA TYV RAM MAN GLA TYV 0.9250
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1TYU; Ligand: RAM MAN GLA TYV RAM MAN GLA TYV; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1tyu.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
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