Receptor
PDB id Resolution Class Description Source Keywords
1TV8 2.2 Å NON-ENZYME: BINDING STRUCTURE OF MOAA IN COMPLEX WITH S-ADENOSYLMETHIONINE STAPHYLOCOCCUS AUREUS TIM BARREL LIGAND BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF THE S-ADENOSYLMETHIONINE-DEPEN ENZYME MOAA AND ITS IMPLICATIONS FOR MOLYBDENUM COF DEFICIENCY IN HUMANS. PROC.NATL.ACAD.SCI.USA V. 101 12870 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DTU A:1502;
Invalid;
none;
submit data
154.251 C4 H10 O2 S2 C([C@...
SAM A:1501;
B:2501;
Valid;
Valid;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
SF4 A:1401;
A:1402;
B:2401;
B:2402;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
351.64 Fe4 S4 [S]12...
SO4 A:1403;
B:2403;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2FB3 2.35 Å NON-ENZYME: BINDING STRUCTURE OF MOAA IN COMPLEX WITH 5'-GTP STAPHYLOCOCCUS AUREUS S-ADENOSYLMETHIONINE TIM BARREL [4FE-4S] CLUSTERS 5-prime -GTPDEOXYADENOSINE LIGAND BINDING PROTEIN
Ref.: BINDING OF 5'-GTP TO THE C-TERMINAL FES CLUSTER OF RADICAL S-ADENOSYLMETHIONINE ENZYME MOAA PROVIDES I INTO ITS MECHANISM PROC.NATL.ACAD.SCI.USA V. 103 6829 2006
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 2FB2 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1TV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2FB3 Kd = 0.29 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 2FB2 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1TV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2FB3 Kd = 0.29 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 2FB2 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1TV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2FB3 Kd = 0.29 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2FB3; Ligand: 5AD; Similar sites found: 56
This union binding pocket(no: 1) in the query (biounit: 2fb3.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5CLO NS8 0.0204 0.40413 None
2 1OLT SAM 0.000192 0.45095 1.76471
3 5HVJ ANP 0.004664 0.43858 1.90476
4 4XH0 ADP 0.02113 0.40175 2.05882
5 4ME6 ADP 0.0166 0.40638 2.35294
6 3VOT ADP 0.01223 0.40167 2.35294
7 5AWM ANP 0.01242 0.40135 2.35294
8 1JPA ANP 0.00145 0.48428 2.5641
9 3VPC ADP 0.0005004 0.41528 3.19149
10 5J6Y BGC 0.01197 0.40649 3.19149
11 5J6Y GLC 0.01197 0.40649 3.19149
12 5LY1 PPI 0.001195 0.47245 3.23529
13 4PZ6 GMP 0.01992 0.40394 3.23529
14 4L3L 5FI 0.007112 0.42501 3.28947
15 1MFI FHC 0.02157 0.40358 3.50877
16 4R33 TRP 0.003145 0.44731 3.52941
17 4R33 SAH 0.003145 0.44731 3.52941
18 4YMJ 4EJ 0.01837 0.4049 3.61842
19 3HAV ATP 0.006711 0.42733 3.67893
20 1VKF CIT 0.01903 0.40477 3.7234
21 2GQS ADP 0.005173 0.40341 3.79747
22 2GQR ADP 0.006076 0.40051 3.79747
23 1M0W ANP 0.005124 0.41098 4.11765
24 4Y0X ADP 0.006386 0.40666 4.41176
25 1Q6O LG6 0.004606 0.40682 4.62963
26 2JKG PRO PRO PRO PRO PRO PRO PRO PRO 0.008134 0.43467 5.58659
27 2QX0 PH2 0.007077 0.43269 5.66038
28 4UTW RFW 0.008871 0.40235 5.67686
29 5C1P ADP 0.007217 0.40829 5.88235
30 1S5O 152 0.00666 0.42488 6.17647
31 4U0O MTA 0.001014 0.42224 6.75676
32 3EXS 5RP 0.009305 0.40318 6.78733
33 1U1J MET 0.02391 0.40175 7.05882
34 4DC2 ADE 0.009455 0.42271 7.14286
35 5DZT AMP 0.0003904 0.49059 7.64706
36 2IF8 ADP 0.01176 0.41133 7.64706
37 1UPR 4IP 0.007568 0.42065 9.7561
38 3T7V SAM 0.0004118 0.42842 10
39 1NJJ GET 0.008956 0.42378 10
40 4NJH 2K8 0.00000003875 0.49036 11.7391
41 4NJH SAM 0.00000003875 0.49036 11.7391
42 1IOW PHY 0.00816 0.42711 12.0915
43 5TH5 MET 0.00001983 0.54974 12.1673
44 3RFA SAM 0.00000008105 0.59791 13.5294
45 4WCX SAM 0.002152 0.40208 14.1176
46 3LQV ADE 0.003691 0.44557 15.3846
47 5WGG SAM 0.00000001454 0.64309 16.7647
48 4M7T SAM 0.00008091 0.47367 18.8889
49 5EXK 5AD 0.0004043 0.48746 21.7523
50 3C8F MT2 0.0001121 0.50832 24.898
51 5VSM MET 0.00000001228 0.60012 32.0755
52 5VSM 5AD 0.00000001228 0.60012 32.0755
53 1O9U ADZ 0.001191 0.48019 33.3333
54 4K37 SAM 0.00000007915 0.6116 36.1765
55 4K38 SAM 0.00000001597 0.60679 36.1765
56 4K39 SAM 0.00000008683 0.5923 36.1765
Pocket No.: 2; Query (leader) PDB : 2FB3; Ligand: GTP; Similar sites found: 144
This union binding pocket(no: 2) in the query (biounit: 2fb3.bio1) has 30 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5CLO NS8 0.04433 0.40413 None
2 2YG2 S1P 0.0111 0.40231 None
3 3VPD ANP 0.007995 0.40552 1.42349
4 3O2K DST 0.004642 0.45255 1.76471
5 1OLT SAM 0.001083 0.45095 1.76471
6 5HVJ ANP 0.008608 0.444 1.90476
7 3H22 B53 0.02787 0.4033 2.0202
8 4XH0 ADP 0.04444 0.40296 2.05882
9 3DAK ANP 0.01901 0.40442 2.06897
10 2OVD DAO 0.0264 0.41386 2.1978
11 5T9C G3P 0.02422 0.41371 2.23881
12 2WSI FAD 0.007672 0.4063 2.28758
13 1TKK ALA GLU 0.007486 0.42015 2.35294
14 3VOT ADP 0.02227 0.40825 2.35294
15 4ME6 ADP 0.03705 0.40594 2.35294
16 5AWM ANP 0.02954 0.40201 2.35294
17 1JPA ANP 0.002845 0.48632 2.5641
18 4YVN EBS 0.02072 0.42003 2.64706
19 4CFT M48 0.01317 0.43 2.94118
20 4FFG 0U8 0.01839 0.40723 2.94118
21 4JR7 GNP 0.01417 0.40377 2.94118
22 1EHI ADP 0.01292 0.40243 2.94118
23 5JSP DQY 0.0339 0.40643 2.98507
24 5FYR INS 0.03394 0.40594 3.02013
25 4CNO 9PY 0.03567 0.40542 3.1746
26 3VPC ADP 0.003537 0.42087 3.19149
27 5J6Y GLC 0.02563 0.40649 3.19149
28 5J6Y BGC 0.02563 0.40649 3.19149
29 5LY2 OGA 0.02946 0.41166 3.23529
30 5LY1 PPI 0.02233 0.40756 3.23529
31 4PZ6 GMP 0.03742 0.40717 3.23529
32 2OG2 MLI 0.02828 0.40081 3.23529
33 1QIN GIP 0.001936 0.40233 3.27869
34 5DBX ANP 0.009624 0.42257 3.35366
35 5J75 6GQ 0.008425 0.42147 3.40909
36 2NLR BGC BGC G2F SHG 0.01881 0.40463 3.4188
37 3AJ6 NGA 0.04466 0.40275 3.4965
38 1MFI FHC 0.04672 0.40358 3.50877
39 2WA4 069 0.01445 0.41385 3.52941
40 2Y7G AAE 0.01323 0.40849 3.5461
41 4YMJ 4EJ 0.03176 0.41081 3.61842
42 1Y9Q MED 0.01917 0.42154 3.64583
43 3HAV ATP 0.01421 0.42998 3.67893
44 1VKF CIT 0.02474 0.41713 3.7234
45 2GQS ADP 0.01325 0.40846 3.79747
46 2GQR ADP 0.0145 0.40662 3.79747
47 3ZGJ RMN 0.01299 0.42884 3.82353
48 4FHD 0TT 0.0005981 0.42158 3.82353
49 4FHD EEM 0.0005981 0.42158 3.82353
50 3V8S 0HD 0.009306 0.4157 3.82353
51 4BG4 ADP 0.009987 0.41078 3.82353
52 1VBR XYS XYP 0.03749 0.40036 3.96341
53 3OFM 4B0 0.02744 0.40006 4.11765
54 4KBA 1QM 0.02639 0.40834 4.22961
55 4Y0X ADP 0.004635 0.43395 4.41176
56 2PZI AXX 0.01982 0.40707 4.41176
57 4L4J NAG NAG BMA MAN NAG 0.01111 0.40204 4.52489
58 4Z3E GAL NGA GLA BGC GAL 0.02192 0.41773 4.54545
59 2XG5 EC2 0.01097 0.43892 4.62428
60 2XG5 EC5 0.01097 0.43892 4.62428
61 1Q6O LG6 0.01235 0.4099 4.62963
62 1Q79 3AT 0.007293 0.42851 4.70588
63 4M1U A2G MBG 0.0005897 0.4901 4.7138
64 5FU3 BGC BGC BGC 0.02986 0.41078 4.71698
65 2WBV SIA 0.02247 0.43011 4.7619
66 5AIG VPR 0.01492 0.41707 5
67 4JH6 FCN 0.01475 0.42148 5.07246
68 3DGY 2GP 0.04352 0.40206 5.15464
69 2BWA GLC BGC 0.01853 0.4123 5.28634
70 2R5V HHH 0.005971 0.43278 5.29412
71 5NCF 8T5 0.04437 0.40031 5.30973
72 2QX0 PH2 0.01625 0.43237 5.66038
73 4IMO PWZ 0.01665 0.41997 5.68182
74 3SHR CMP 0.03099 0.40095 5.68562
75 1I82 BGC BGC 0.0006605 0.49977 5.82011
76 5C1P ADP 0.01469 0.4135 5.88235
77 4ZU4 4TG 0.01102 0.40556 6.08108
78 5M42 FMN 0.01484 0.40613 6.09319
79 1P0Z FLC 0.03454 0.4069 6.10687
80 4RDL FUC GAL NDG FUC 0.004078 0.45822 6.16883
81 1S5O 152 0.009199 0.43729 6.17647
82 4UEC MGT 0.02751 0.40806 6.41026
83 5TPV TYD 0.04525 0.40118 6.53595
84 4U0O MTA 0.003673 0.42708 6.75676
85 3EXS 5RP 0.01923 0.40772 6.78733
86 3M3E GAL A2G NPO 0.004467 0.4575 6.8323
87 2HY0 306 0.01574 0.41203 6.8323
88 1U1J MET 0.04916 0.40175 7.05882
89 4DC2 ADE 0.01757 0.42712 7.14286
90 2BOS GLA GAL 0.001112 0.46091 7.35294
91 2BOS GLA GAL GLC 0.00148 0.44176 7.35294
92 5FWJ MMK 0.009983 0.43026 7.35294
93 5F6U 5VK 0.007174 0.44456 7.64331
94 5DZT AMP 0.0006202 0.50334 7.64706
95 2QK4 ATP 0.01539 0.42052 7.64706
96 2IF8 ADP 0.02142 0.41728 7.64706
97 4LRJ ANP 0.01379 0.40764 7.69231
98 4FE2 ADP 0.02272 0.40413 7.84314
99 3M94 M7M 0.01289 0.42145 7.93651
100 3TII ANP 0.02123 0.40931 7.94118
101 5F2T PLM 0.009982 0.40435 8.11688
102 3KO0 TFP 0.03005 0.41251 8.91089
103 2P7Q GG6 0.007268 0.44224 9.02256
104 4KYS VIB 0.02892 0.41031 9.11765
105 2HZQ STR 0.0229 0.41624 9.1954
106 5K2M ADP 0.007855 0.40005 9.43396
107 1UPR 4IP 0.01295 0.42444 9.7561
108 3T7V SAM 0.002143 0.43029 10
109 1NJJ GET 0.01426 0.41806 10
110 5L8L ADP 0.03093 0.40099 10.2564
111 3VPB ADP 0.00449 0.40726 10.7143
112 2JGB MGT 0.02045 0.41835 10.7692
113 4WOE ADP 0.007906 0.43978 10.8824
114 5I8T LAC 0.03419 0.40641 11.1732
115 5A67 3PO 0.006446 0.445 11.3208
116 5BVB DOG 0.019 0.40106 11.3636
117 4NJH 2K8 0.000002473 0.50654 11.7391
118 4NJH SAM 0.000002473 0.50654 11.7391
119 5TH5 MET 0.00006312 0.55117 12.1673
120 5TH5 7C5 0.001655 0.42499 12.1673
121 1MEX RAC 0.02399 0.40661 12.2066
122 1Y7P RIP 0.03972 0.40378 13.0045
123 3RFA SAM 0.0000008427 0.59791 13.5294
124 4WCX SAM 0.008795 0.40372 14.1176
125 1EOM NAG MAN MAN MAN NAG GAL NAG GAL 0.005868 0.41791 14.1379
126 3H9R TAK 0.03359 0.40287 14.6789
127 4IAW LIZ 0.0148 0.41725 14.8936
128 3LQV ADE 0.008191 0.44557 15.3846
129 3I4X DST 0.01526 0.42071 15.5882
130 5WGG SAM 0.0000001141 0.64615 16.7647
131 4M7T SAM 0.0004283 0.47367 18.8889
132 1TFZ 869 0.002474 0.43111 20.2941
133 5EXK 5AD 0.0009665 0.49091 21.7523
134 5LXT ACP 0.005863 0.40829 24.4755
135 3C8F MT2 0.0003048 0.50832 24.898
136 1BHX ASP PHE GLU GLU ILE 0.01027 0.42527 26.6667
137 5KEW 6SB 0.04389 0.40146 31.25
138 5VSM 5AD 0.0000003163 0.60271 32.0755
139 5VSM MET 0.0000003402 0.60131 32.0755
140 1O9U ADZ 0.002162 0.48452 33.3333
141 5C79 PBU 0.04071 0.40894 35.3333
142 4K37 SAM 0.0000006223 0.6116 36.1765
143 4K38 SAM 0.000000371 0.60679 36.1765
144 4K39 SAM 0.000001117 0.5923 36.1765
Pocket No.: 3; Query (leader) PDB : 2FB3; Ligand: MET; Similar sites found: 52
This union binding pocket(no: 3) in the query (biounit: 2fb3.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5CLO NS8 0.01859 0.40413 None
2 1OLT SAM 0.0005392 0.42518 1.76471
3 5HVJ ANP 0.004208 0.43858 1.90476
4 4XH0 ADP 0.01864 0.40241 2.05882
5 3VOT ADP 0.009366 0.40493 2.35294
6 1JPA ANP 0.001317 0.48428 2.5641
7 3VPC ADP 0.0003097 0.41656 3.19149
8 5J6Y BGC 0.01094 0.40649 3.19149
9 5J6Y GLC 0.01094 0.40649 3.19149
10 5LY1 PPI 0.001081 0.47245 3.23529
11 4PZ6 GMP 0.01815 0.40394 3.23529
12 4L3L 5FI 0.006494 0.43099 3.28947
13 1MFI FHC 0.01967 0.40358 3.50877
14 4R33 TRP 0.00278 0.45441 3.52941
15 4R33 SAH 0.00278 0.45441 3.52941
16 4W6Z 8ID 0.0323 0.40413 3.52941
17 4YMJ 4EJ 0.01838 0.40282 3.61842
18 3HAV ATP 0.007258 0.42345 3.67893
19 1VKF CIT 0.01546 0.4071 3.7234
20 1M0W ANP 0.00457 0.41746 4.11765
21 4Y0X ADP 0.004638 0.40666 4.41176
22 2XOC ADP 0.01368 0.42882 5.36398
23 2JKG PRO PRO PRO PRO PRO PRO PRO PRO 0.007462 0.43467 5.58659
24 2QX0 PH2 0.009062 0.426 5.66038
25 5C1P ADP 0.007275 0.40584 5.88235
26 1S5O 152 0.005427 0.42756 6.17647
27 1RE8 BD2 0.03734 0.40713 6.17647
28 4U0O MTA 0.0008298 0.42078 6.75676
29 1U1J MET 0.02194 0.40175 7.05882
30 4DC2 ADE 0.01049 0.4186 7.14286
31 5DZT AMP 0.002486 0.44784 7.64706
32 2IF8 ADP 0.01181 0.40902 7.64706
33 1UPR 4IP 0.03732 0.40078 9.7561
34 3T7V SAM 0.0003526 0.42348 10
35 1NJJ GET 0.008482 0.423 10
36 4NJH SAM 0.00000007589 0.47321 11.7391
37 4NJH 2K8 0.00000007589 0.47321 11.7391
38 1IOW PHY 0.009851 0.42698 12.0915
39 5TH5 MET 0.00001715 0.54974 12.1673
40 3RFA SAM 0.0000004462 0.55871 13.5294
41 4WCX SAM 0.00178 0.40088 14.1176
42 3LQV ADE 0.003359 0.44557 15.3846
43 5WGG SAM 0.00000003922 0.61251 16.7647
44 4M7T SAM 0.0000579 0.47367 18.8889
45 5EXK 5AD 0.005699 0.42659 21.7523
46 3C8F MT2 0.0004657 0.48527 24.898
47 5VSM 5AD 0.00000002641 0.57438 32.0755
48 5VSM MET 0.00000002641 0.57438 32.0755
49 1O9U ADZ 0.001076 0.48019 33.3333
50 4K37 SAM 0.00000007956 0.5971 36.1765
51 4K38 SAM 0.00000001676 0.59302 36.1765
52 4K39 SAM 0.00000008293 0.57988 36.1765
Pocket No.: 4; Query (leader) PDB : 2FB3; Ligand: MET; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2fb3.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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