Receptor
PDB id Resolution Class Description Source Keywords
1TLG 2.2 Å NON-ENZYME: BINDING STRUCTURE OF A TUNICATE C-TYPE LECTIN COMPLEXED WITH D- GALACTOSE POLYANDROCARPA MISAKIENSIS C-TYPE LECTIN GALACTOSE-SPECIFIC CARBOHYDRATE BINDING
Ref.: THE STRUCTURE OF A TUNICATE C-TYPE LECTIN FROM POLYANDROCARPA MISAKIENSIS COMPLEXED WITH D -GALACTOSE. J.MOL.BIOL. V. 290 867 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:201;
A:202;
B:201;
B:202;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
GAL A:126;
B:126;
Valid;
Valid;
none;
none;
Kd = 0.44 mM
180.156 C6 H12 O6 C([C@...
ZN A:301;
A:302;
A:303;
B:301;
B:302;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1TLG 2.2 Å NON-ENZYME: BINDING STRUCTURE OF A TUNICATE C-TYPE LECTIN COMPLEXED WITH D- GALACTOSE POLYANDROCARPA MISAKIENSIS C-TYPE LECTIN GALACTOSE-SPECIFIC CARBOHYDRATE BINDING
Ref.: THE STRUCTURE OF A TUNICATE C-TYPE LECTIN FROM POLYANDROCARPA MISAKIENSIS COMPLEXED WITH D -GALACTOSE. J.MOL.BIOL. V. 290 867 1999
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 1TLG Kd = 0.44 mM GAL C6 H12 O6 C([C@@H]1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 1TLG Kd = 0.44 mM GAL C6 H12 O6 C([C@@H]1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 1TLG Kd = 0.44 mM GAL C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GAL; Similar ligands found: 141
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL 1 1
2 BMA 1 1
3 GXL 1 1
4 GLA 1 1
5 ALL 1 1
6 GLC 1 1
7 BGC 1 1
8 GIV 1 1
9 MAN 1 1
10 WOO 1 1
11 32O 0.653846 0.866667
12 RIB 0.653846 0.866667
13 FUB 0.653846 0.866667
14 Z6J 0.653846 0.866667
15 AHR 0.653846 0.866667
16 BMA BMA MAN 0.545455 0.823529
17 GLA BGC 0.511628 0.848485
18 LAK 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 GLA GLC 0.511628 0.848485
23 GAL GAL 0.511628 0.848485
24 MLB 0.511628 0.848485
25 BMA GLA 0.511628 0.848485
26 BMA BMA BMA BMA BMA BMA MAN 0.5 0.823529
27 YDR 0.5 0.8
28 MAN BMA BMA BMA BMA BMA 0.5 0.823529
29 GLC GLC GLC GLC BGC 0.488889 0.848485
30 GLC GLC GLC 0.488889 0.848485
31 MAN MAN MAN 0.488889 0.848485
32 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
33 BGP 0.461538 0.675
34 G6P 0.461538 0.675
35 M6P 0.461538 0.675
36 A6P 0.461538 0.675
37 M6D 0.461538 0.675
38 BG6 0.461538 0.675
39 SHG 0.457143 0.875
40 GAF 0.457143 0.875
41 G2F 0.457143 0.875
42 X6X 0.457143 0.777778
43 2FG 0.457143 0.875
44 G3F 0.457143 0.875
45 PA1 0.457143 0.777778
46 1GN 0.457143 0.777778
47 GCS 0.457143 0.777778
48 2H5 0.457143 0.875
49 LB2 0.454545 0.848485
50 BGC BMA 0.454545 0.848485
51 BGC GAL 0.454545 0.848485
52 MAL 0.454545 0.848485
53 GLC GAL 0.454545 0.848485
54 M3M 0.454545 0.848485
55 GLA GAL 0.454545 0.848485
56 MAB 0.454545 0.848485
57 GLC BGC 0.454545 0.848485
58 BMA BMA 0.454545 0.848485
59 LBT 0.454545 0.848485
60 MAL MAL 0.454545 0.823529
61 CBK 0.454545 0.848485
62 GLA GLA 0.454545 0.848485
63 MAN GLC 0.454545 0.848485
64 CBI 0.454545 0.848485
65 N9S 0.454545 0.848485
66 GAL GLC 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 B2G 0.454545 0.848485
69 BGC GLC 0.454545 0.848485
70 LAT 0.454545 0.848485
71 GAL BGC 0.454545 0.848485
72 3MG 0.444444 0.875
73 TCB 0.444444 0.8
74 GLC SGC 0.444444 0.8
75 YIO 0.441176 0.870968
76 2GS 0.432432 0.875
77 BGC BGC 0.431818 0.848485
78 2M4 0.431818 0.848485
79 MAN MAN 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 CT3 0.416667 0.848485
84 GLC BGC GLC 0.416667 0.848485
85 MLR 0.416667 0.848485
86 GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
87 GLC GLC GLC GLC GLC 0.416667 0.848485
88 GAL FUC 0.416667 0.848485
89 BMA BMA BMA 0.416667 0.848485
90 CTR 0.416667 0.848485
91 BGC GLC GLC 0.416667 0.848485
92 BGC GLC GLC GLC GLC 0.416667 0.848485
93 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
94 GLC GAL GAL 0.416667 0.848485
95 B4G 0.416667 0.848485
96 CEX 0.416667 0.848485
97 MAN BMA BMA BMA BMA 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
100 CTT 0.416667 0.848485
101 GLC GLC BGC 0.416667 0.848485
102 DXI 0.416667 0.848485
103 GLC GLC BGC GLC GLC GLC GLC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
107 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
108 MTT 0.416667 0.848485
109 BMA MAN BMA 0.416667 0.848485
110 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
111 CE5 0.416667 0.848485
112 GAL GAL GAL 0.416667 0.848485
113 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
114 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
115 GLA GAL GLC 0.416667 0.848485
116 CE6 0.416667 0.848485
117 GLC BGC BGC BGC BGC 0.416667 0.848485
118 GLC BGC BGC 0.416667 0.848485
119 MAN BMA BMA 0.416667 0.848485
120 MT7 0.416667 0.848485
121 GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
122 CE8 0.416667 0.848485
123 CEY 0.416667 0.848485
124 BGC BGC BGC 0.408163 0.848485
125 BGC BGC BGC BGC BGC 0.408163 0.848485
126 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
127 SGC SGC BGC 0.408163 0.8
128 GLC BGC BGC BGC 0.408163 0.848485
129 BGC BGC BGC ASO BGC BGC ASO 0.408163 0.848485
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 TRE 0.405405 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 BM3 0.404762 0.7
135 NDG 0.404762 0.7
136 NAG 0.404762 0.7
137 HSQ 0.404762 0.7
138 A2G 0.404762 0.7
139 NGA 0.404762 0.7
140 FUB AHR AHR 0.4 0.764706
141 AHR AHR AHR 0.4 0.764706
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found: 77
This union binding pocket(no: 1) in the query (biounit: 1tlg.bio3) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2AMT 1AA 0.002231 0.48904 None
2 4G9N NGA 0.0001757 0.47476 None
3 5C2N NAG 0.004157 0.44194 None
4 4LOK 1YD 0.0231 0.42255 None
5 1RC0 KT5 0.01156 0.40778 None
6 4M20 COA 0.04211 0.40548 None
7 3P8N L4T 0.0335 0.40395 None
8 2BW7 APC 0.02349 0.44193 1.6
9 2ORV 4TA 0.007551 0.43815 1.6
10 5UOX 8GY 0.01453 0.41909 1.6
11 2BW7 ECS 0.04276 0.40696 1.6
12 2YIP YIO 0.001369 0.40668 1.6
13 5J8O 6GZ 0.007942 0.42515 1.6129
14 3U40 ADN 0.002297 0.4585 2.4
15 1B57 PGH 0.002676 0.44464 2.4
16 4LO2 GAL BGC 0.0005593 0.43904 2.4
17 5B4B LP5 0.01228 0.41745 2.4
18 1P18 7HP 0.009432 0.41057 2.4
19 1P18 PRP 0.009432 0.41057 2.4
20 1TKK ALA GLU 0.008659 0.40621 2.4
21 2HFP NSI 0.04561 0.40184 2.4
22 1GAR U89 0.004722 0.43406 3.2
23 1QGQ UDP 0.006236 0.41185 3.2
24 4JLS 3ZE 0.007808 0.40922 3.2
25 3UCJ AZM 0.02111 0.40255 3.2
26 5ULJ 0WD 0.0375 0.40225 3.2
27 5MF5 C2E 0.01001 0.44898 4
28 1KNM LAT 0.0005833 0.44516 4
29 3GFZ C2E 0.01424 0.4309 4
30 3N3T C2E 0.01416 0.4277 4
31 2B8T THM 0.00786 0.42666 4
32 5ETJ IM5 0.02106 0.41197 4
33 5TUZ 7L6 0.005003 0.4547 4.8
34 5TUZ SAM 0.005003 0.4547 4.8
35 2D24 XYS XYS 0.0003112 0.44657 4.8
36 3HV8 C2E 0.009387 0.43818 4.8
37 5ALC TIQ 0.02466 0.4296 4.8
38 4JAW NGT GAL 0.001555 0.42158 4.8
39 3D91 REM 0.03489 0.41368 4.8
40 4QAR ADE 0.008415 0.40956 4.8
41 3H0A D30 0.03723 0.40717 4.8
42 3N9R TD3 0.002291 0.43881 5.6
43 4QJL COA 0.01623 0.40082 5.6
44 5F7J ADE 0.005794 0.40769 6.4
45 3K56 IS3 0.01708 0.40046 6.4
46 1JE1 GMP 0.001165 0.47761 7.2
47 1VHW ADN 0.0015 0.47224 7.2
48 4OUJ LBT 0.000521 0.42928 7.2
49 3QPB URA 0.002257 0.42085 7.2
50 1N2X SAM 0.04169 0.40114 7.2
51 4ZGR NGA GAL 0.001033 0.45178 8
52 1F0X FAD 0.02772 0.40667 8
53 5CCM 4ZX 0.0223 0.40341 8
54 5CCM SAM 0.01914 0.40341 8
55 5IOK ACE GLN THR ALA ARG KCR SER THR 0.02994 0.40049 8
56 5N5D SAM 0.01278 0.4263 8.40708
57 5AFN L0B 0.00724 0.44453 8.8
58 5MX4 HPA 0.01259 0.40306 9.6
59 2Y6P CTP 0.0158 0.40384 10.4
60 2QV6 GTP 0.02387 0.41198 12
61 2H21 SAM 0.0118 0.41035 12
62 1NW4 IMH 0.002349 0.46338 12.8
63 3KRO DST 0.03158 0.40137 12.8
64 3KRO IPE 0.03158 0.40137 12.8
65 3HRD FAD 0.04702 0.41728 13.6
66 5T67 JHZ 0.04291 0.41357 16
67 2C91 NAP 0.01184 0.41596 20.8
68 2BP1 NDP 0.01512 0.40412 20.8
69 4NVQ 2OD 0.01114 0.4235 21.6
70 4NVQ SAH 0.01069 0.4235 21.6
71 2VUZ NAG BMA NAG MAN MAN NAG NAG 0.000004204 0.58741 28
72 5JQ1 ZPF 0.000001401 0.59449 36
73 2GGX NPJ 0.000001264 0.61928 41.6
74 5KTI TRE 6X6 0.000004967 0.60415 41.6
75 1PWB GLC GLC 0.000007148 0.53432 41.6
76 1PWB GLC 0.000009037 0.52591 41.6
77 1G1T SIA GAL MAG FUC 0.00000001942 0.71972 43.2
Pocket No.: 2; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1tlg.bio3) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found: 9
This union binding pocket(no: 3) in the query (biounit: 1tlg.bio1) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1K27 MTM 0.003136 0.46693 None
2 3DER ALA LYS 0.003766 0.43133 1.6
3 2PTZ PAH 0.0213 0.40667 1.6
4 3OZG SSI 0.006623 0.41469 4.8
5 2AC7 ADN 0.00872 0.43447 8
6 4DA6 GA2 0.002058 0.4145 8
7 1R6W 164 0.006177 0.44208 11.2
8 3FXU TSU 0.01245 0.41171 15.2
9 4DN8 BMA 0.00009032 0.50546 39.2
Pocket No.: 4; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1tlg.bio1) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1tlg.bio4) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1tlg.bio4) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1tlg.bio2) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1tlg.bio2) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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