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Receptor
PDB id Resolution Class Description Source Keywords
1TLG 2.2 Å NON-ENZYME: BINDING STRUCTURE OF A TUNICATE C-TYPE LECTIN COMPLEXED WITH D- GALACTOSE POLYANDROCARPA MISAKIENSIS C-TYPE LECTIN GALACTOSE-SPECIFIC CARBOHYDRATE BINDING
Ref.: THE STRUCTURE OF A TUNICATE C-TYPE LECTIN FROM POLYANDROCARPA MISAKIENSIS COMPLEXED WITH D -GALACTOSE. J.MOL.BIOL. V. 290 867 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:201;
A:202;
B:201;
B:202;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
GAL A:126;
B:126;
Valid;
Valid;
none;
none;
Kd = 0.44 mM
180.156 C6 H12 O6 C([C@...
ZN A:301;
A:302;
A:303;
B:301;
B:302;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1TLG 2.2 Å NON-ENZYME: BINDING STRUCTURE OF A TUNICATE C-TYPE LECTIN COMPLEXED WITH D- GALACTOSE POLYANDROCARPA MISAKIENSIS C-TYPE LECTIN GALACTOSE-SPECIFIC CARBOHYDRATE BINDING
Ref.: THE STRUCTURE OF A TUNICATE C-TYPE LECTIN FROM POLYANDROCARPA MISAKIENSIS COMPLEXED WITH D -GALACTOSE. J.MOL.BIOL. V. 290 867 1999
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1TLG Kd = 0.44 mM GAL C6 H12 O6 C([C@@H]1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1TLG Kd = 0.44 mM GAL C6 H12 O6 C([C@@H]1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1TLG Kd = 0.44 mM GAL C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GAL; Similar ligands found: 142
No: Ligand ECFP6 Tc MDL keys Tc
1 WOO 1 1
2 GLC 1 1
3 BGC 1 1
4 ALL 1 1
5 BMA 1 1
6 GXL 1 1
7 GIV 1 1
8 GAL 1 1
9 MAN 1 1
10 GLA 1 1
11 Z6J 0.653846 0.866667
12 32O 0.653846 0.866667
13 RIB 0.653846 0.866667
14 FUB 0.653846 0.866667
15 AHR 0.653846 0.866667
16 MLB 0.511628 0.848485
17 GLC GLC 0.511628 0.848485
18 BGC GLC 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 BMA GLA 0.511628 0.848485
23 GLA BGC 0.511628 0.848485
24 MAN MAN 0.511628 0.848485
25 GLA GLC 0.511628 0.848485
26 BMA MAN 0.511628 0.848485
27 GAL GLC 0.511628 0.848485
28 GAL GAL 0.511628 0.848485
29 LAK 0.511628 0.848485
30 GLC BGC 0.511628 0.848485
31 YDR 0.5 0.8
32 GLC GLC GLC GLC BGC 0.488889 0.848485
33 GLC GLC GLC 0.488889 0.848485
34 MAN MAN MAN 0.488889 0.848485
35 BMA MAN MAN 0.488889 0.848485
36 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
37 EMZ 0.472222 0.794118
38 BG6 0.461538 0.675
39 BGP 0.461538 0.675
40 G6P 0.461538 0.675
41 M6P 0.461538 0.675
42 M6D 0.461538 0.675
43 A6P 0.461538 0.675
44 GAF 0.457143 0.875
45 SHG 0.457143 0.875
46 2FG 0.457143 0.875
47 G2F 0.457143 0.875
48 2H5 0.457143 0.875
49 GCS 0.457143 0.777778
50 1GN 0.457143 0.777778
51 X6X 0.457143 0.777778
52 PA1 0.457143 0.777778
53 95Z 0.457143 0.777778
54 G3F 0.457143 0.875
55 NGR 0.454545 0.848485
56 MAL 0.454545 0.848485
57 MAN GLC 0.454545 0.848485
58 GAL BGC 0.454545 0.848485
59 GLA GLA 0.454545 0.848485
60 BGC BMA 0.454545 0.848485
61 M3M 0.454545 0.848485
62 GLA GAL 0.454545 0.848485
63 MAB 0.454545 0.848485
64 GLC GAL 0.454545 0.848485
65 B2G 0.454545 0.848485
66 LBT 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 LAT 0.454545 0.848485
69 BGC GAL 0.454545 0.848485
70 CBI 0.454545 0.848485
71 CBK 0.454545 0.848485
72 N9S 0.454545 0.848485
73 LB2 0.454545 0.848485
74 3MG 0.444444 0.875
75 TCB 0.444444 0.8
76 GLC SGC 0.444444 0.8
77 YIO 0.441176 0.870968
78 2GS 0.432432 0.875
79 2M4 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 MAN BMA BMA 0.416667 0.848485
84 BMA MAN BMA 0.416667 0.848485
85 CTR 0.416667 0.848485
86 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
87 GLA GAL BGC 0.416667 0.848485
88 CE5 0.416667 0.848485
89 MLR 0.416667 0.848485
90 CE6 0.416667 0.848485
91 MT7 0.416667 0.848485
92 BMA BMA BMA 0.416667 0.848485
93 GLC BGC BGC BGC BGC 0.416667 0.848485
94 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
95 BGC BGC BGC BGC BGC 0.416667 0.848485
96 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
97 BGC GLC GLC 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 MAN BMA BMA BMA BMA 0.416667 0.848485
100 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
101 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
102 MAN BMA BMA BMA BMA BMA 0.416667 0.848485
103 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 CTT 0.416667 0.848485
107 GLA GAL GLC 0.416667 0.848485
108 MTT 0.416667 0.848485
109 GLC BGC BGC BGC 0.416667 0.848485
110 GLC GLC BGC 0.416667 0.848485
111 CEY 0.416667 0.848485
112 B4G 0.416667 0.848485
113 CE8 0.416667 0.848485
114 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
115 GAL FUC 0.416667 0.848485
116 DXI 0.416667 0.848485
117 GLC BGC GLC 0.416667 0.848485
118 CT3 0.416667 0.848485
119 GAL GAL GAL 0.416667 0.848485
120 GLC GLC GLC GLC GLC 0.416667 0.848485
121 BGC BGC BGC BGC 0.416667 0.848485
122 BGC BGC BGC 0.416667 0.848485
123 BGC BGC GLC 0.416667 0.848485
124 CEX 0.416667 0.848485
125 GLC GAL GAL 0.416667 0.848485
126 BGC GLC GLC GLC GLC 0.416667 0.848485
127 GLC BGC BGC 0.416667 0.848485
128 GS1 GLC GS1 0.408163 0.8
129 SGC SGC BGC 0.408163 0.8
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 TRE 0.405405 0.848485
135 NDG 0.404762 0.7
136 NGA 0.404762 0.7
137 NAG 0.404762 0.7
138 HSQ 0.404762 0.7
139 A2G 0.404762 0.7
140 BM3 0.404762 0.7
141 FUB AHR AHR 0.4 0.764706
142 AHR AHR AHR AHR AHR AHR 0.4 0.764706
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found with APoc: 130
This union binding pocket(no: 1) in the query (biounit: 1tlg.bio3) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2AMT 1AA None
2 1K27 MTM None
3 4G9N NGA None
4 5C2N NAG None
5 3GFS FMN None
6 1RC0 KT5 None
7 4M20 COA None
8 5HC8 61G None
9 5HC8 PIS None
10 5HC8 ISY None
11 3P8N L4T None
12 2BW7 APC 1.6
13 2ORV 4TA 1.6
14 6E2O S0L 1.6
15 3DER ALA LYS 1.6
16 1W4R TTP 1.6
17 6GCB GSH 1.6
18 3R35 4CO 1.6
19 2BW7 ECS 1.6
20 2YIP YIO 1.6
21 2PTZ PAH 1.6
22 5RHN 8BR 1.73913
23 3U40 ADN 2.4
24 5VJE GOS 2.4
25 4LO2 GAL BGC 2.4
26 5B4B LP5 2.4
27 1P19 IMP 2.4
28 1TKK ALA GLU 2.4
29 2HFP NSI 2.4
30 1A69 FMB 3.2
31 5W3K 9TY 3.2
32 5W3K NDP 3.2
33 1GAR U89 3.2
34 5HPZ 68G 3.2
35 1QGQ UDP 3.2
36 5ULJ 0WD 3.2
37 4JLS 3ZE 3.2
38 5MF5 C2E 4
39 5M1T C2E 4
40 1KNM LAT 4
41 2B8T THM 4
42 2QQ0 TMP 4
43 2QQ0 ADP 4
44 3GFZ C2E 4
45 3N3T C2E 4
46 1BZY IMU 4
47 5ETJ IM5 4
48 6AR9 3L4 4
49 4AVV GHE 4
50 4AVV CD 4
51 5TUZ SAM 4.8
52 5TUZ 7L6 4.8
53 3HV8 C2E 4.8
54 2D24 XYS XYS 4.8
55 4JAW NGT GAL 4.8
56 4RFM 3P6 4.8
57 3OZG SSI 4.8
58 3D91 REM 4.8
59 4QAR ADE 4.8
60 3H0A D30 4.8
61 2QX0 APC 4.8
62 1PEA ACM 4.8
63 5ZFJ 9BF 4.8
64 1QMG APX 5.6
65 3N9R TD3 5.6
66 3AJ6 NGA 5.6
67 2ZX7 ZX7 5.6
68 4RHY 3QG 5.6
69 4QJL COA 5.6
70 6FXR UDP 6.4
71 1GPM AMP 6.4
72 5F7J ADE 6.4
73 1O7Q GAL NAG 6.4
74 1O7Q UDP 6.4
75 3K56 IS3 6.4
76 1VHW ADN 7.2
77 1JE1 GMP 7.2
78 2FJK 13P 7.2
79 4OUJ LBT 7.2
80 1N2X SAM 7.2
81 1KQ4 FAD 7.2
82 3QPB URA 7.2
83 4ZGR NGA GAL 8
84 2AC7 ADN 8
85 4DA6 GA2 8
86 1F0X FAD 8
87 5JCA FAD 8
88 5CCM SAM 8
89 5CCM 4ZX 8
90 5IOK ACE GLN THR ALA ARG KCR SER THR 8
91 1XPJ TLA 8
92 5N5D SAM 8.40708
93 1Z34 2FD 8.8
94 4JTA NAP 8.8
95 5OUH L0B 8.8
96 1ODJ GMP 9.6
97 6F4W FMC 9.6
98 4UXH T5A 10.4
99 3IP6 PRO 10.4
100 5B6D C5P 10.4
101 2Y6P CTP 10.4
102 1R6W 164 11.2
103 1R27 MGD 11.2
104 4KQW NAP 11.2
105 2QV6 GTP 12
106 2H21 SAM 12
107 1NW4 IMH 12.8
108 1B5E DCM 12.8
109 3KRO DST 12.8
110 3KRO IPE 12.8
111 3HRD FAD 13.6
112 1B09 PC 13.6
113 3GFB NAD 15.2
114 3FXU TSU 15.2
115 5T67 JHZ 16
116 1CF2 NAP 18.4
117 5W7D MYR 19.2
118 2C91 NAP 20.8
119 2BP1 NDP 20.8
120 4NVQ SAH 21.6
121 4NVQ 2OD 21.6
122 3PAK MAN 22.4
123 5G6U YJM 33.6
124 5JQ1 ZPF 36
125 4DN8 BMA 39.2
126 5KTI TRE 6X6 41.6
127 1PWB GLC GLC 41.6
128 2GGX NPJ 41.6
129 1PWB GLC 41.6
130 1G1T SIA GAL MAG FUC 43.2
Pocket No.: 2; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found with APoc: 29
This union binding pocket(no: 2) in the query (biounit: 1tlg.bio3) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2YPI PGA None
2 4OWK NGA None
3 1MI3 NAD None
4 3FUR Z12 2.4
5 3G9E RO7 2.4
6 4R4U COA 2.4
7 1WXI AMP 3.2
8 2IV3 UDP 4
9 5BVE 4VG 4
10 5C79 PBU 4
11 1HGX 5GP 4.8
12 4P86 5GP 4.8
13 3P0F BAU 5.6
14 2FQO HYI 5.6
15 2P4S DIH 5.6
16 4WP9 ZDA 6.4
17 4K4D HFQ 6.4
18 2J83 BAT 7.2
19 5Z6T NAP 7.2
20 1CS4 101 8
21 1CS4 FOK 8
22 4YFB PAC 8
23 5XNC MTA 9.6
24 4U0O MTA 10.4
25 5Y6Q FAD 11.2
26 4FMU 0UM 12
27 4XDY NAI 15.2
28 4A22 TD4 20.8
29 3WYJ H78 23.2
Pocket No.: 3; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found with APoc: 2
This union binding pocket(no: 3) in the query (biounit: 1tlg.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4PTZ FMN 3.2
2 2A8Y MTA 4
Pocket No.: 4; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1tlg.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1tlg.bio4) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found with APoc: 2
This union binding pocket(no: 6) in the query (biounit: 1tlg.bio4) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2WZG UPG 4
2 5BO9 CSF 4.8
Pocket No.: 7; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1tlg.bio2) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1TLG; Ligand: GAL; Similar sites found with APoc: 2
This union binding pocket(no: 8) in the query (biounit: 1tlg.bio2) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4LTN FMN 5.6
2 5AZ1 NDP 12.8
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