-->
Receptor
PDB id Resolution Class Description Source Keywords
1T65 1.66 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE ANDROGEN RECEPTOR LIGAND BINDING DO DHT AND A PEPTIDE DERIVED FORM ITS PHYSIOLOGICAL COACTIVATOB OX 2 BOUND IN A NON-HELICAL CONFORMATION HOMO SAPIENS ANDROGEN RECEPTOR LIGAND BINDING DOMAIN GRIP1 NR BOX2 COACTICRYSTAL STRUCTURE NON-HELICAL HORMONE-GROWTH FACTOR COMPLE
Ref.: THE MOLECULAR MECHANISMS OF COACTIVATOR UTILIZATION LIGAND-DEPENDENT TRANSACTIVATION BY THE ANDROGEN RE J.BIOL.CHEM. V. 280 8060 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DHT A:931;
Valid;
none;
submit data
290.44 C19 H30 O2 C[C@]...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3V49 1.7 Å NON-ENZYME: SIGNAL_HORMONE STRUCTURE OF AR LBD WITH ACTIVATOR PEPTIDE AND SARM INHIBITO HOMO SAPIENS DIARYLHYDANTOIN SYNTHESIS SARM ANTIANDROGEN LIGAND BINDIDOMAIN TESTOSTERONE DIHYDROTESTOSTERONE TRANSCRIPTION S(SELECTIVE ANDROGEN RECEPTOR MODULATOR)
Ref.: DISCOVERY OF DIARYLHYDANTOINS AS NEW SELECTIVE ANDR RECEPTOR MODULATORS. J.MED.CHEM. V. 55 8225 2012
Members (31)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 5JJM - DHT C19 H30 O2 C[C@]12CCC....
2 1T7M - DHT C19 H30 O2 C[C@]12CCC....
3 1T65 - DHT C19 H30 O2 C[C@]12CCC....
4 1T5Z - DHT C19 H30 O2 C[C@]12CCC....
5 2Q7K - TES C19 H28 O2 C[C@]12CC[....
6 4OKT - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
7 3V4A - PK1 C17 H14 Cl2 N2 O2 S C[C@]1(C(=....
8 1T7F - DHT C19 H30 O2 C[C@]12CCC....
9 1T74 - DHT C19 H30 O2 C[C@]12CCC....
10 3V49 ic50 = 9.6 nM PK0 C19 H14 F3 N3 O3 C[C@]1(C(=....
11 4OH5 - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
12 4OKW - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
13 2Q7L - TES C19 H28 O2 C[C@]12CC[....
14 4OK1 - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
15 4OEZ - DHT C19 H30 O2 C[C@]12CCC....
16 3L3X - DHT C19 H30 O2 C[C@]12CCC....
17 1T73 - DHT C19 H30 O2 C[C@]12CCC....
18 2Q7I - TES C19 H28 O2 C[C@]12CC[....
19 4OEY - DHT C19 H30 O2 C[C@]12CCC....
20 1T7R - DHT C19 H30 O2 C[C@]12CCC....
21 2Q7J - TES C19 H28 O2 C[C@]12CC[....
22 2AO6 - R18 C19 H24 O2 C[C@@]1(CC....
23 4OFR - DHT C19 H30 O2 C[C@]12CCC....
24 3L3Z - DHT C19 H30 O2 C[C@]12CCC....
25 4OFU - DHT C19 H30 O2 C[C@]12CCC....
26 1T63 - DHT C19 H30 O2 C[C@]12CCC....
27 1XOW - R18 C19 H24 O2 C[C@@]1(CC....
28 1T76 - DHT C19 H30 O2 C[C@]12CCC....
29 4OKX - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
30 4OHA - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
31 1T79 - DHT C19 H30 O2 C[C@]12CCC....
70% Homology Family (33)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 5JJM - DHT C19 H30 O2 C[C@]12CCC....
2 1T7M - DHT C19 H30 O2 C[C@]12CCC....
3 1T65 - DHT C19 H30 O2 C[C@]12CCC....
4 1T5Z - DHT C19 H30 O2 C[C@]12CCC....
5 2Q7K - TES C19 H28 O2 C[C@]12CC[....
6 4OKT - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
7 3V4A - PK1 C17 H14 Cl2 N2 O2 S C[C@]1(C(=....
8 1T7F - DHT C19 H30 O2 C[C@]12CCC....
9 1T74 - DHT C19 H30 O2 C[C@]12CCC....
10 3V49 ic50 = 9.6 nM PK0 C19 H14 F3 N3 O3 C[C@]1(C(=....
11 4OH5 - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
12 4OKW - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
13 2Q7L - TES C19 H28 O2 C[C@]12CC[....
14 4OK1 - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
15 4OEZ - DHT C19 H30 O2 C[C@]12CCC....
16 3L3X - DHT C19 H30 O2 C[C@]12CCC....
17 1T73 - DHT C19 H30 O2 C[C@]12CCC....
18 2Q7I - TES C19 H28 O2 C[C@]12CC[....
19 4OEY - DHT C19 H30 O2 C[C@]12CCC....
20 1T7R - DHT C19 H30 O2 C[C@]12CCC....
21 2Q7J - TES C19 H28 O2 C[C@]12CC[....
22 2AO6 - R18 C19 H24 O2 C[C@@]1(CC....
23 4OFR - DHT C19 H30 O2 C[C@]12CCC....
24 3L3Z - DHT C19 H30 O2 C[C@]12CCC....
25 4OFU - DHT C19 H30 O2 C[C@]12CCC....
26 1T63 - DHT C19 H30 O2 C[C@]12CCC....
27 1XOW - R18 C19 H24 O2 C[C@@]1(CC....
28 1T76 - DHT C19 H30 O2 C[C@]12CCC....
29 4OKX - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
30 4OHA - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
31 1T79 - DHT C19 H30 O2 C[C@]12CCC....
32 2OVH ic50 = 1 nM AS0 C28 H35 N O4 C[C@]12C[C....
33 4OAR ic50 = 0.038 nM 2S0 C30 H37 N O4 CC(=O)[C@]....
50% Homology Family (61)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 5JJM - DHT C19 H30 O2 C[C@]12CCC....
2 1T7M - DHT C19 H30 O2 C[C@]12CCC....
3 1T65 - DHT C19 H30 O2 C[C@]12CCC....
4 1T5Z - DHT C19 H30 O2 C[C@]12CCC....
5 2Q7K - TES C19 H28 O2 C[C@]12CC[....
6 4OKT - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
7 3V4A - PK1 C17 H14 Cl2 N2 O2 S C[C@]1(C(=....
8 1T7F - DHT C19 H30 O2 C[C@]12CCC....
9 1T74 - DHT C19 H30 O2 C[C@]12CCC....
10 3V49 ic50 = 9.6 nM PK0 C19 H14 F3 N3 O3 C[C@]1(C(=....
11 4OH5 - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
12 4OKW - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
13 2Q7L - TES C19 H28 O2 C[C@]12CC[....
14 4OK1 - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
15 4OEZ - DHT C19 H30 O2 C[C@]12CCC....
16 3L3X - DHT C19 H30 O2 C[C@]12CCC....
17 1T73 - DHT C19 H30 O2 C[C@]12CCC....
18 2Q7I - TES C19 H28 O2 C[C@]12CC[....
19 4OEY - DHT C19 H30 O2 C[C@]12CCC....
20 1T7R - DHT C19 H30 O2 C[C@]12CCC....
21 2Q7J - TES C19 H28 O2 C[C@]12CC[....
22 2AO6 - R18 C19 H24 O2 C[C@@]1(CC....
23 4OFR - DHT C19 H30 O2 C[C@]12CCC....
24 3L3Z - DHT C19 H30 O2 C[C@]12CCC....
25 4OFU - DHT C19 H30 O2 C[C@]12CCC....
26 1T63 - DHT C19 H30 O2 C[C@]12CCC....
27 1XOW - R18 C19 H24 O2 C[C@@]1(CC....
28 1T76 - DHT C19 H30 O2 C[C@]12CCC....
29 4OKX - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
30 4OHA - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
31 1T79 - DHT C19 H30 O2 C[C@]12CCC....
32 4E2J - MOF C27 H30 Cl2 O6 C[C@@H]1C[....
33 4P6W Ki = 0.7 nM MOF C27 H30 Cl2 O6 C[C@@H]1C[....
34 5UFS Ki = 3.2 nM 1TA C24 H31 F O6 C[C@]12C[C....
35 4UDB Ki = 0.18 nM CV7 C28 H38 O6 C[C@]12C[C....
36 4UDA Ki = 6.3 nM DEX C22 H29 F O5 C[C@@H]1C[....
37 5MWY Kd = 0.37 uM YNU C24 H30 O6 C[C@]12CCC....
38 5MWP Kd = 0.37 uM ECV C20 H18 F N3 O5 CNC(=O)C[C....
39 1M2Z - DEX C22 H29 F O5 C[C@@H]1C[....
40 3K22 - JZS C22 H21 F6 N5 O3 Cc1cc(c2cn....
41 3MNO - DEX C22 H29 F O5 C[C@@H]1C[....
42 3E7C - 866 C23 H21 Cl2 F4 N5 O3 CCN(C[C@@]....
43 4P6X Ki = 91 nM HCY C21 H30 O5 C[C@]12CCC....
44 3MNP - DEX C22 H29 F O5 C[C@@H]1C[....
45 3MNE - DEX C22 H29 F O5 C[C@@H]1C[....
46 2A3I - C0R C21 H30 O4 C[C@]12CCC....
47 4UDC - DEX C22 H29 F O5 C[C@@H]1C[....
48 5NFT - 8W8 C25 H21 F4 N3 O3 C[C@@H]([C....
49 5G5W ic50 = 0.0027 uM R8C C24 H19 F4 N3 O2 C[C@@H]([C....
50 4CSJ ic50 = 4.9 nM NN7 C25 H27 F N4 O2 S Cc1cc(c(c(....
51 6EL7 - B9T C20 H19 Br F2 N4 O2 C[C@@H]([C....
52 5NFP - 8W5 C25 H34 O6 CCC[C@@H]1....
53 4UDD - CV7 C28 H38 O6 C[C@]12C[C....
54 6EL9 ic50 = 3.8 nM B9W C27 H28 F2 N4 O3 CC(C)[C@@H....
55 6EL6 ic50 = 6.3 nM B9Q C26 H25 F N4 O3 C[C@@H]([C....
56 5G3J ic50 = 63 nM E7T C22 H19 F5 N2 O3 CC[C@@H]1C....
57 3GN8 - DEX C22 H29 F O5 C[C@@H]1C[....
58 2OVH ic50 = 1 nM AS0 C28 H35 N O4 C[C@]12C[C....
59 4OAR ic50 = 0.038 nM 2S0 C30 H37 N O4 CC(=O)[C@]....
60 4LSJ ic50 = 4.38 nM LSJ C25 H25 N O4 S CC/C(=C/1c....
61 3BQD - DAY C30 H36 N2 O4 C[C@@H]1C[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DHT; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 BDT 1 1
2 DHT 1 1
3 CI2 0.602941 0.78125
4 3KL 0.551282 0.805556
5 5SD 0.536232 0.78125
6 ANO 0.536232 0.78125
7 AON 0.530303 0.935484
8 AOM 0.530303 0.935484
9 ENM 0.472527 0.659091
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3V49; Ligand: PK0; Similar sites found with APoc: 303
This union binding pocket(no: 1) in the query (biounit: 3v49.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 3QDV NDG None
2 4WG0 CHD None
3 4V1F BQ1 None
4 5MWE TCE None
5 1XZ3 ICF None
6 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO None
7 2VWA PTY None
8 5A7C 5D4 None
9 1UO4 PIH None
10 1L0I PSR None
11 2CB8 MYA None
12 4UYG 73B None
13 4OAS 2SW None
14 5AIP 4HP None
15 4UOH ADP None
16 6CS9 PIO None
17 3AI3 SOE 0.760456
18 6A0S NDP 1.12782
19 4K10 NI9 1.50376
20 5M37 9SZ 1.73913
21 5EXA 5SO 1.73913
22 3P9T TCL 1.82648
23 2JC9 ADN 1.8797
24 5OSW DIU 1.8797
25 1UKW FAD 1.8797
26 5XNA SHV 2.17391
27 5CHR 4NC 2.18978
28 1WEI ADE 2.22222
29 3O01 DXC 2.25564
30 4MRP GSH 2.25564
31 5NM7 GLY 2.25564
32 3ETG GTP 2.25564
33 5U5G 7VD 2.25564
34 2UW1 GVM 2.25564
35 2BP1 FLC 2.25564
36 5IUY BOG 2.25564
37 4B1V LAB 2.25564
38 5FPN KYD 2.25564
39 3MKH FAD 2.25564
40 2OHV NHL 2.27273
41 2BHW NEX 2.58621
42 2XN3 ID8 2.63158
43 3KAL HGS 2.63158
44 2RH1 CLR 2.63158
45 2XN5 FUN 2.63158
46 6BMM OLB 2.63158
47 3B9Z CO2 2.63158
48 3ZUY TCH 2.63158
49 1KPG 16A 2.63158
50 5OM2 DXT 2.63158
51 6AP8 BNY 2.63158
52 1XMY ROL 2.63158
53 5IM3 DTP 2.63158
54 1SBR VIB 3
55 6CB2 OLC 3.00752
56 4RW3 TDA 3.00752
57 2A1L PCW 3.00752
58 2Q8G AZX 3.00752
59 1GVE CIT 3.00752
60 1DMH MCT 3.00752
61 4M52 M52 3.00752
62 3R9C ECL 3.00752
63 3KYQ DPV 3.01508
64 5X13 HC4 3.19149
65 3JRS A8S 3.36538
66 1NF8 BOG 3.38164
67 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 3.38346
68 5KOD IAC 3.38346
69 2C0U FAD NBT 3.38346
70 2Z9I GLY ALA THR VAL 3.38346
71 2JFN UMA 3.38346
72 3SE5 ANP 3.38346
73 6EOP F15 3.38346
74 1UUY PPI 3.59281
75 2V95 HCY 3.7594
76 1FX8 BOG 3.7594
77 5AZC PGT 3.7594
78 4ARE FLC 3.7594
79 1TV5 N8E 3.7594
80 2G2Y MLI 3.7594
81 4ORM FMN 3.7594
82 4ORM ORO 3.7594
83 4ORM 2V6 3.7594
84 1YC4 43P 3.78788
85 2Q4X HMH 4.0724
86 2F2G HMH 4.0724
87 3TDC 0EU 4.13534
88 1T0S BML 4.13534
89 4L1F FAD 4.13534
90 1SJD NPG 4.13534
91 4M51 BEZ 4.13534
92 5NCB JZ3 4.13534
93 3QUZ QUV 4.30622
94 3IA4 MTX 4.32099
95 1JGS SAL 4.34783
96 1J78 OLA 4.51128
97 2BCG GER 4.51128
98 3ZQE DXC 4.51128
99 1ZED PNP 4.51128
100 4RYV ZEA 4.51613
101 5UC4 83S 4.54545
102 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 4.60251
103 3B6C SDN 4.70085
104 1Q3A NGH 4.84848
105 5UC9 MYR 4.86726
106 2JHP GUN 4.88722
107 4G86 BNT 4.88722
108 3HP9 CF1 4.88722
109 4XNV BUR 4.88722
110 4URN NOV 4.88889
111 2WOR 2AN 5
112 5C9J DAO 5.05051
113 3W54 RNB 5.26316
114 5CKS GAL 5.26316
115 1U25 IHS 5.26316
116 1A05 IPM 5.26316
117 4DXJ 0M9 5.26316
118 3KP6 SAL 5.29801
119 4DE3 DN8 5.32319
120 3AXM 6PG 5.42636
121 2YLD CMO 5.51181
122 3R1V AZB 5.51181
123 3DFR MTX 5.55556
124 2F7A BEZ 5.60345
125 5XK9 DMA 5.60345
126 6DIO CIT 5.6391
127 6H8S FSZ 5.6391
128 4I3G BGC 5.6391
129 5OLK DTP 5.6391
130 3KDJ A8S 5.6391
131 1ZGA HMK 5.6391
132 4G2R H1L 5.6391
133 2D5Z L35 5.67376
134 2GBB CIT 5.76923
135 5CX6 CDP 6.01504
136 1ZPD CIT 6.01504
137 5OKL PAM 6.01504
138 2OZ5 7XY 6.01504
139 3RMK BML 6.0241
140 5N26 CPT 6.04396
141 1OW4 2AN 6.20155
142 4V3I ASP LEU THR ARG PRO 6.22568
143 6BR8 6OU 6.34921
144 3B99 U51 6.39098
145 5AHS FAD 6.39098
146 1SO2 666 6.39098
147 6BR9 6OU 6.39098
148 1B4N GUA 6.39098
149 5XJ7 87O 6.46766
150 1S8G DAO 6.61157
151 1HBK MYR 6.74157
152 1Q7E MET 6.76692
153 4URX FK1 6.76692
154 6BVM EBV 6.76692
155 6BVL EBY 6.76692
156 6BVJ EAS 6.76692
157 6BVK EAV 6.76692
158 6BVI EC4 6.76692
159 3HNC TTP 6.76692
160 6D5H FV7 6.76692
161 4M73 M72 6.76692
162 4M73 SAH 6.76692
163 3TL1 JRO 6.91824
164 5W7B MYR 7.0922
165 4IA6 EIC 7.14286
166 3Q8G PEE 7.14286
167 3GXO MQA 7.14286
168 4YSX E23 7.14286
169 5X3R 7Y3 7.31707
170 5V4R MGT 7.40741
171 5ZQ4 AMP 7.69231
172 2PRG BRL 7.89474
173 3G9E RO7 7.89474
174 3EE4 MYR 7.89474
175 4HDK 13X 7.89474
176 4F4S EFO 7.89474
177 3HYW DCQ 7.89474
178 2QZT PLM 8.10811
179 2HHP FLC 8.27068
180 3LN0 52B 8.27068
181 2ZUV NDG 8.27068
182 5EY0 GTP 8.27068
183 3NJQ NJQ 8.29016
184 4WGF HX2 8.29268
185 6D28 NEC 8.64662
186 1MID LAP 8.79121
187 5DCH 1YO 8.85417
188 3G4Q MCH 8.90411
189 6BTN E8M 8.91089
190 6CGN DA 9.02256
191 3R9V DXC 9.02256
192 5TK8 7D5 9.27835
193 2JAP J01 9.31174
194 4RHP PEF 9.3617
195 1R6N 434 9.47867
196 5MOB A8S 9.48276
197 1MT1 AG2 9.73451
198 1N13 AG2 9.73451
199 2QQC AG2 9.82143
200 2QQD AG2 9.82143
201 3RET PYR 9.90099
202 3RET SAL 9.90099
203 5B0I BOG 10.2041
204 5UGW GSH 10.2857
205 5M36 9SZ 10.5263
206 5B25 4QJ 10.5263
207 1DTL BEP 10.559
208 2ALG DAO 10.8696
209 3KO0 TFP 10.8911
210 5FUS DAO 10.9023
211 2D5X L35 11.3475
212 4DS8 A8S 11.9617
213 5FQ0 FLC 12.2807
214 1SQL GUN 12.3288
215 1NU4 MLA 12.3711
216 3D9F N6C 12.406
217 3D9F FAD 12.406
218 1N8V BDD 12.5
219 3F8C HT1 12.6984
220 5X8Q 82R 12.7907
221 1NQ7 ARL 13.1148
222 3KDU NKS 13.1579
223 3ET1 ET1 13.1579
224 2GWH PCI 13.1579
225 3FEI CTM 13.1579
226 1K7L 544 13.1579
227 4OR7 25U 13.3333
228 5JO1 6LM 13.5135
229 4OIC A8S 13.9098
230 3L1N PLM 13.9175
231 5OCA 9QZ 14.2857
232 3NMV PYV 14.6067
233 2Z77 NCA 15.1079
234 4RJD TFP 15.1515
235 3KMR EQN 15.4135
236 1DB1 VDX 15.444
237 5X80 SAL 15.625
238 2XEM SSV 16
239 2LBD REA 16.1654
240 1RL4 BL5 16.4894
241 1FCZ 156 18.2979
242 5U83 ZN8 18.8679
243 3GZ9 D32 19.1729
244 1XVB 3BR 19.4118
245 1XVB BHL 19.4118
246 4O4Z N2O 20.1299
247 2WDQ CBE 20.8696
248 5WZU 7W3 21.1382
249 1XAP TTB 22.1805
250 4DM8 REA 22.1805
251 4DK7 0KS 23.4818
252 3IPQ 965 24.0602
253 5NNT DPV 24.3243
254 3BEJ MUF 24.3697
255 3DCT 064 24.6809
256 3OKI OKI 24.8927
257 5ICK FEZ 25.3275
258 3RUU 37G 25.3275
259 4OIV XX9 25.6637
260 4QJR PIZ 26.1224
261 1ZDT PEF 26.556
262 1NRL SRL 27.0677
263 1M13 HYF 27.0677
264 2Y69 CHD 27.1429
265 1YMT DR9 27.6423
266 2HFP NSI 27.6596
267 5Z84 CHD 28.5714
268 5W97 CHD 28.5714
269 5ZCO CHD 28.5714
270 1X0P FAD 28.6713
271 3ET3 ET1 29.3233
272 6AD9 KK4 29.3233
273 2P4Y C03 29.3233
274 3T03 3T0 29.3233
275 5AAV GW5 30.9524
276 2QA8 GEN 31.0078
277 2QZO KN1 31.0078
278 4OGQ 7PH 31.0345
279 3UU7 2OH 31.0757
280 2E2R 2OH 31.1475
281 2QE4 JJ3 31.4516
282 1YYE 196 31.5789
283 2BJ4 OHT 31.746
284 1YUC EPH 31.7647
285 3UUD EST 31.8725
286 3UUA 0CZ 31.8725
287 1YOK P6L 32.0312
288 1PZL MYR 32.4895
289 5UNJ RJW 33.4694
290 1ZDU P3A 33.4694
291 3FS1 MYR 33.4783
292 2I0G I0G 33.8521
293 1U3R 338 35.2697
294 3AQT RCO 36.3636
295 1HG4 LPP 36.4662
296 1YP0 PEF 37.2385
297 1FM9 9CR 37.395
298 1FM9 570 37.395
299 1DKF OLA 38.1974
300 1DKF BMS 38.1974
301 4M8E 29V 38.5281
302 4POJ 2VP 38.5281
303 3H0A 9RA 39.4737
APoc FAQ
Feedback