Receptor
PDB id Resolution Class Description Source Keywords
1SLB 2.3 Å NON-ENZYME: BINDING X-RAY CRYSTALLOGRAPHY REVEALS CROSSLINKING OF MAMMALIAN LECT (GALECTIN-1) BY BIANTENNARY COMPLEX TYPE SACCHARIDES BOS TAURUS COMPLEX(LECTIN-SACCHARIDE) COMPLEX(LECTIN-SACCHARIDE) COMPL
Ref.: CROSSLINKING OF MAMMALIAN LECTIN (GALECTIN-1) BY CO BIANTENNARY SACCHARIDES. NAT.STRUCT.BIOL. V. 1 863 1994
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG MAN GAL BMA NAG MAN NAG GAL A:351;
Valid;
none;
submit data
1438.3 n/a O=C(N...
NAG MAN GAL MAN MAN NAG GAL C:361;
Valid;
none;
submit data
1235.11 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1SLT 1.9 Å NON-ENZYME: BINDING STRUCTURE OF S-LECTIN, A DEVELOPMENTALLY REGULATED VERTEBRATE BETA-GALACTOSIDE BINDING PROTEIN BOS TAURUS LECTIN
Ref.: STRUCTURE OF S-LECTIN, A DEVELOPMENTALLY REGULATED VERTEBRATE BETA-GALACTOSIDE-BINDING PROTEIN. PROC.NATL.ACAD.SCI.USA V. 91 1428 1994
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 1SLC - NAG MAN GAL BMA NDG MAN NAG GAL n/a n/a
2 1SLB - NAG MAN GAL MAN MAN NAG GAL n/a n/a
3 1SLT - NDG GAL n/a n/a
4 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
70% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 4XBL Kd = 340 uM GAL NAG n/a n/a
2 4Y24 Kd = 0.22 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
3 3OYW Kd = 78 uM TDG C12 H22 O10 S C([C@@H]1[....
4 2ZKN - GAL BGC n/a n/a
5 3T2T - MQT C17 H22 O8 Cc1ccc(cc1....
6 3OY8 Kd = 220 uM GAL GCO n/a n/a
7 1SLC - NAG MAN GAL BMA NDG MAN NAG GAL n/a n/a
8 1SLB - NAG MAN GAL MAN MAN NAG GAL n/a n/a
9 1SLT - NDG GAL n/a n/a
10 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
50% Homology Family (94)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 5NF9 Kd = 4.7 uM 8VW C22 H32 N2 O12 CC(=O)N[C@....
2 5E8A Kd = 0.034 uM 5KS C28 H30 F2 N6 O8 S c1cc(ccc1c....
3 1A3K - GAL NAG n/a n/a
4 3T1M Kd = 0.91 mM DQT C23 H27 N O7 Cc1ccc(cc1....
5 4LBL Kd = 11 uM BGC SIA GAL n/a n/a
6 2NMN Kd = 260 uM GAL BGC n/a n/a
7 4R9B - LAT C12 H22 O11 C([C@@H]1[....
8 2NN8 Kd = 260 uM LAT C12 H22 O11 C([C@@H]1[....
9 4JC1 Kd = 50 uM TDG C12 H22 O10 S C([C@@H]1[....
10 4R9A - LAT C12 H22 O11 C([C@@H]1[....
11 5EXO - 5SY C19 H22 O9 CC(=O)O[C@....
12 5E88 Kd = 0.065 uM 5KT C24 H28 N6 O8 S3 c1cscc1c2c....
13 4R9D - LAT C12 H22 O11 C([C@@H]1[....
14 1KJL Kd = 67 uM GAL NAG n/a n/a
15 3T1L Kd = 0.55 mM MQT C17 H22 O8 Cc1ccc(cc1....
16 2XG3 Kd = 18.2 uM UNU GAL NAG n/a n/a
17 4LBJ Kd = 0.39 uM GAL NAG GAL BGC n/a n/a
18 4R9C - LAT C12 H22 O11 C([C@@H]1[....
19 3ZSJ Kd = 231 uM LAT C12 H22 O11 C([C@@H]1[....
20 4LBM Kd = 0.97 uM BGC GAL NAG GAL n/a n/a
21 1KJR Kd = 0.88 uM BEK GAL NAG n/a n/a
22 3AYE - LAT C12 H22 O11 C([C@@H]1[....
23 5E89 Kd = 0.014 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
24 4LBO Kd = 1.7 uM BGC GAL SIA n/a n/a
25 2NMO Kd = 260 uM GAL BGC n/a n/a
26 3AYC Kd = 57 uM GAL NGA GAL BGC SIA n/a n/a
27 4JCK Kd = 4.3 mM 1LL C12 H22 O10 S C([C@@H]1[....
28 5NFA Kd = 5.6 uM 8VQ C24 H36 N2 O12 CC(=O)N[C@....
29 4LBK Kd = 0.32 uM GAL NAG GAL BGC n/a n/a
30 4RL7 - LAT C12 H22 O11 C([C@@H]1[....
31 3AYD Kd = 65 uM NPO A2G GAL n/a n/a
32 4LBN Kd = 0.65 uM GLC GAL NAG GAL n/a n/a
33 2D6N - GAL NAG n/a n/a
34 2D6M - LBT C12 H22 O11 C([C@@H]1[....
35 2D6O - NAG GAL GAL NAG n/a n/a
36 4XBN Kd = 93 uM GAL NAG n/a n/a
37 5H9R Kd = 0.84 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
38 5H9P Kd = 0.068 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
39 5DG2 - GAL GLC n/a n/a
40 5EWS - GAL BGC n/a n/a
41 4XBL Kd = 340 uM GAL NAG n/a n/a
42 4Y24 Kd = 0.22 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
43 3T2T - MQT C17 H22 O8 Cc1ccc(cc1....
44 3OY8 Kd = 220 uM GAL GCO n/a n/a
45 2EAL - GAL NGA A2G n/a n/a
46 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
47 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
48 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
49 2ZHM - NAG GAL GAL NAG GAL n/a n/a
50 2EAK - LBT C12 H22 O11 C([C@@H]1[....
51 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
52 5H9S Kd = 87 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
53 5H9Q Kd = 38 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
54 4XBQ Kd = 270 uM GAL NAG n/a n/a
55 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
56 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
57 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
58 3VKO - SIA GAL NAG n/a n/a
59 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
60 5T7T Kd = 2.1 uM GAL NAG n/a n/a
61 3I8T Kd = 600 uM LBT C12 H22 O11 C([C@@H]1[....
62 3WV6 - GAL BGC n/a n/a
63 3NV2 - GAL NDG n/a n/a
64 3NV4 - SIA GAL BGC n/a n/a
65 3NV3 - GAL NAG MAN n/a n/a
66 3WUD Kd = 41 uM GLC GAL n/a n/a
67 3GAL - 1GN C6 H13 N O5 C([C@@H]1[....
68 4UW6 - VV7 C69 H73 N20 O39 [H]1c2c(cc....
69 2GAL - GAL C6 H12 O6 C([C@@H]1[....
70 4GAL - GAL BGC n/a n/a
71 4UW3 - 50G C31 H50 N10 O18 c1c(nnn1[C....
72 4UW4 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
73 3ZXE Kd = 450 uM PGZ C22 H28 N O8 P S Cc1ccc(cc1....
74 5GAL - NAG GAL n/a n/a
75 4UW5 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
76 1GAN - NDG GAL n/a n/a
77 1A78 - TDG C12 H22 O10 S C([C@@H]1[....
78 5DUW Kd = 510 uM 5GO C12 H22 O14 S C([C@@H]1[....
79 5DUV Kd = 1300 uM LAT C12 H22 O11 C([C@@H]1[....
80 5DUX Kd = 380 uM LAT FUC n/a n/a
81 4WVV - LBT C12 H22 O11 C([C@@H]1[....
82 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
83 4YLZ Kd = 270 uM LAT NAG GAL n/a n/a
84 5CBL - LAT C12 H22 O11 C([C@@H]1[....
85 4YM2 Kd = 1400 uM SGA BGC n/a n/a
86 4YM3 Kd = 1900 uM LAT C12 H22 O11 C([C@@H]1[....
87 4YM1 Kd = 580 uM LAT FUC n/a n/a
88 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
89 1WLD - GAL BGC n/a n/a
90 5NFB Kd = 0.77 uM 8VT C30 H40 N2 O13 CC(=O)N[C@....
91 5NF7 Kd = 37.5 uM 8VZ C16 H28 N2 O11 CC(=O)N[C@....
92 1SLB - NAG MAN GAL MAN MAN NAG GAL n/a n/a
93 1SLT - NDG GAL n/a n/a
94 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAG MAN GAL BMA NAG MAN NAG GAL; Similar ligands found: 146
No: Ligand ECFP6 Tc MDL keys Tc
1 MAN BMA NAG NAG MAN NAG GAL GAL 1 1
2 NAG MAN GAL BMA NDG MAN NAG GAL 1 1
3 NAG MAN MAN MAN NAG GAL NAG GAL 1 1
4 NAG MAN GAL BMA NAG MAN NAG GAL 1 1
5 NAG MAN BMA NDG MAN NAG GAL 0.945055 1
6 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.894737 0.979592
7 NAG BMA NAG MAN MAN NAG NAG 0.880435 1
8 NAG NAG BMA MAN MAN 0.784946 0.979592
9 NAG MAN GAL MAN MAN NAG GAL 0.784946 0.979592
10 MAN MAN NAG MAN NAG 0.784946 0.979592
11 M5G 0.78 0.979592
12 BMA NAG MAN MAN MAN MAN MAN MAN MAN 0.760417 0.918367
13 NAG GAL GAL NAG 0.719101 0.979592
14 GAL NAG GAL NAG GAL NAG 0.719101 1
15 NAG BMA MAN MAN MAN MAN 0.684211 0.918367
16 NAG NAG BMA MAN MAN NAG NAG 0.682243 0.924528
17 NAG NAG BMA MAN MAN MAN MAN 0.669725 0.90566
18 GLA GAL NAG 0.629214 0.918367
19 MAN BMA NAG 0.629214 0.918367
20 NAG GAL GAL 0.629214 0.918367
21 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.626168 0.849057
22 GLC GAL NAG GAL 0.621053 0.918367
23 ASN NAG NAG BMA MAN MAN NAG NAG 0.615385 0.907407
24 NAG MAN MAN MAN NAG 0.612245 0.979592
25 NAG GAL NAG 0.595745 0.979592
26 NAG GAL GAL NAG GAL 0.59375 0.979592
27 NAG NAG BMA MAN NAG 0.587156 0.924528
28 NDG GAL 0.581395 0.918367
29 NLC 0.581395 0.918367
30 GAL NDG 0.581395 0.918367
31 GAL NAG MAN 0.580645 0.918367
32 MAN NAG GAL 0.580645 0.918367
33 NAG MAN MAN 0.556701 0.918367
34 NAG MAN BMA 0.556701 0.918367
35 GAL BGC NAG GAL 0.556701 0.918367
36 WZ5 0.556604 0.92
37 NAG NAG NAG NAG 0.554348 1
38 NAG NAG NAG NAG NAG NAG NAG NAG 0.554348 1
39 NDG NAG NAG NDG NAG 0.554348 1
40 NAG NAG NAG 0.554348 1
41 NDG NAG NAG NAG 0.554348 1
42 NAG NAG NAG NAG NDG 0.554348 1
43 NAG NAG NAG NAG NDG NAG 0.554348 1
44 NAG NAG NAG NAG NAG NAG 0.554348 1
45 CTO 0.554348 1
46 NAG NAG NAG NDG 0.554348 1
47 NAG NAG NDG 0.554348 1
48 NDG NAG NAG 0.554348 1
49 NDG NAG NAG NDG 0.554348 1
50 NAG NAG NAG NAG NAG 0.554348 1
51 DR2 0.541667 0.938776
52 NDG GAL FUC 0.541667 0.938776
53 FUC GAL NAG 0.541667 0.938776
54 FUL GAL NAG 0.541667 0.938776
55 FUC GAL NDG 0.541667 0.938776
56 FUC BGC GAL NAG GAL 0.537037 0.938776
57 NAG NAG BMA MAN 0.533333 0.90566
58 MAN MAN MAN BMA MAN MAN MAN 0.528846 0.68
59 TCG 0.525253 0.844828
60 CTO TMX 0.525253 0.844828
61 MAN MAN MAN BMA MAN 0.520408 0.673469
62 CBS CBS 0.51087 0.979592
63 NAG NDG 0.51087 0.979592
64 NAG GDL 0.51087 0.979592
65 CBS 0.51087 0.979592
66 G6S NAG 0.510204 0.714286
67 GAL NAG GAL 0.51 0.882353
68 NGA GLA GAL BGC 0.504854 0.918367
69 FUC GAL NAG GAL BGC 0.5 0.938776
70 NAG GAL BGC 0.5 0.918367
71 BGC GAL NAG GAL FUC FUC 0.495575 0.959184
72 GLC GAL NAG GAL FUC FUC 0.495575 0.959184
73 1GN ACY GAL ACY 1GN BGC GAL BGC 0.495413 0.979592
74 ACY 1GN GAL 1GN BGC ACY GAL BGC 0.495413 0.979592
75 AML MAN MAN MAN MAN MAN MAN MAN MAN 0.495413 0.618182
76 MMA MAN NAG MAN NAG NAG 0.495327 0.98
77 WZ4 0.491667 0.867925
78 NAG NAG BMA 0.490196 0.90566
79 LAT NAG GAL 0.490196 0.918367
80 BGC GAL NAG GAL 0.490196 0.918367
81 NAG NDG BMA 0.490196 0.90566
82 GAL NAG GAL BGC 0.490196 0.918367
83 A2G GAL NAG FUC 0.486239 1
84 GAL NGA GLA BGC GAL 0.485714 0.918367
85 NAG MAN MMA 0.48 0.92
86 NAG NAG NAG NAG NAG NAG NAG 0.476636 0.907407
87 FUC GAL NAG A2G 0.468468 0.907407
88 NAG FUC 0.468085 0.897959
89 NAG BMA MAN MAN MAN MAN MAN 0.466667 0.673077
90 GLA GAL NAG FUC GAL GLC 0.452991 0.938776
91 SIA GAL NAG GAL BGC 0.451128 0.924528
92 BGC GAL NAG SIA GAL 0.451128 0.924528
93 SIA GAL NAG GAL GLC 0.451128 0.924528
94 GLC GAL NAG GAL FUC A2G 0.446281 1
95 A2G GAL NAG FUC GAL GLC 0.446281 1
96 NGA GAL BGC 0.445545 0.918367
97 MAN MAN MAN GLC 0.443299 0.673469
98 NAG GCU NAG GCD 0.434426 0.907407
99 KDO MAN MAN MAN MAN MAN 0.432 0.673077
100 8VZ 0.431579 0.96
101 MAN MAN NAG 0.428571 0.882353
102 NAG NAG BMA BMA 0.427273 0.907407
103 BMA NGT MAN MAN 0.424779 0.677966
104 GAL NDG FUC FUC 0.424528 0.959184
105 BDZ 0.424528 0.959184
106 FUC NDG GAL FUC 0.424528 0.959184
107 BCW 0.424528 0.959184
108 FUC GAL NAG FUC 0.424528 0.959184
109 FUC GAL NDG FUC 0.424528 0.959184
110 GAL NAG FUC FUC 0.424528 0.959184
111 FUC NAG GAL FUC 0.424528 0.959184
112 UNU GAL NAG 0.422018 0.96
113 GLA GAL GAL 0.421053 0.673469
114 GLA GAL BGC 0.421053 0.673469
115 BMA MAN MAN 0.421053 0.673469
116 MAN MAN BMA MAN 0.42 0.673469
117 MAN MAN MAN MAN 0.42 0.673469
118 DR3 0.419048 0.938776
119 NAG GAL FUC 0.419048 0.938776
120 BGC BGC BGC BGC BGC BGC BGC BGC 0.418367 0.673469
121 BGC BGC BGC BGC 0.418367 0.673469
122 GAL NGA 0.416667 0.918367
123 A2G GAL 0.416667 0.918367
124 GAL A2G 0.416667 0.918367
125 FUC BGC GAL NAG 0.415929 0.938776
126 FUC GAL NAG GAL FUC 0.415929 0.959184
127 GAL NGA A2G 0.415842 0.96
128 OPM MAN MAN 0.413462 0.607143
129 HS2 0.413462 0.882353
130 4U1 0.41129 0.942308
131 NAG GAL SIA 0.41129 0.924528
132 GLC GLC GLC GLC GLC GLC 0.41 0.673469
133 A2G GAL BGC FUC 0.408696 0.938776
134 MAN MAN BMA 0.404255 0.673469
135 MAN MMA MAN 0.40404 0.68
136 GLC GLC GLC BGC 0.401961 0.673469
137 MAN BMA MAN MAN MAN 0.401961 0.673469
138 M5S 0.401961 0.673469
139 GAL NAG SIA GAL 0.401515 0.924528
140 SIA GAL NAG GAL 0.401515 0.924528
141 SN5 SN5 0.4 0.811321
142 GAL NDG FUC 0.4 0.938776
143 GAL NAG FUC 0.4 0.938776
144 FUC NDG GAL 0.4 0.938776
145 FUC NAG GAL 0.4 0.938776
146 3PV 0.4 0.867925
Ligand no: 2; Ligand: NAG MAN GAL MAN MAN NAG GAL; Similar ligands found: 213
No: Ligand ECFP6 Tc MDL keys Tc
1 NAG MAN GAL MAN MAN NAG GAL 1 1
2 NAG MAN MAN MAN NAG 0.788235 1
3 MAN BMA NAG NAG MAN NAG GAL GAL 0.784946 0.979592
4 NAG MAN GAL BMA NAG MAN NAG GAL 0.784946 0.979592
5 NAG MAN GAL BMA NDG MAN NAG GAL 0.784946 0.979592
6 NAG MAN MAN MAN NAG GAL NAG GAL 0.784946 0.979592
7 NAG MAN BMA NDG MAN NAG GAL 0.744898 0.979592
8 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.705882 1
9 NAG BMA NAG MAN MAN NAG NAG 0.686869 0.979592
10 NAG GAL GAL NAG GAL 0.651685 1
11 NAG NAG BMA MAN MAN NAG NAG 0.641509 0.90566
12 NAG NAG BMA MAN MAN MAN MAN 0.62963 0.923077
13 NAG MAN BMA 0.629214 0.9375
14 NAG MAN MAN 0.629214 0.9375
15 NAG NAG BMA MAN NAG 0.621359 0.90566
16 M5G 0.607477 1
17 GAL NAG MAN 0.602273 0.9375
18 MAN NAG GAL 0.602273 0.9375
19 NAG NAG BMA MAN MAN 0.6 1
20 MAN MAN NAG MAN NAG 0.6 1
21 GLC GAL NAG GAL 0.591398 0.9375
22 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.584906 0.865385
23 BMA NAG MAN MAN MAN MAN MAN MAN MAN 0.582524 0.9375
24 ASN NAG NAG BMA MAN MAN NAG NAG 0.564103 0.888889
25 GAL NAG GAL NAG GAL NAG 0.56383 0.979592
26 NAG GAL GAL NAG 0.56383 1
27 GAL NAG GAL 0.55914 0.9
28 FUC BGC GAL NAG GAL 0.553398 0.958333
29 MAN MAN MAN BMA MAN MAN MAN 0.545455 0.693878
30 WZ5 0.543689 0.938776
31 MAN MAN MAN BMA MAN 0.537634 0.6875
32 NAG NAG BMA 0.536842 0.923077
33 NAG NDG BMA 0.536842 0.923077
34 BMA MAN MAN 0.535714 0.6875
35 GAL BGC NAG GAL 0.526316 0.9375
36 NAG NAG BMA MAN 0.519608 0.923077
37 NAG BMA MAN MAN MAN MAN 0.509804 0.9375
38 MMA MAN NAG MAN NAG NAG 0.509804 0.96
39 FUC GAL NAG GAL FUC 0.509804 0.938776
40 MAN MAN MAN MAN MAN MAN MAN MAN 0.509615 0.611111
41 GLC GLC GLC GLC 0.494382 0.6875
42 GAL NDG 0.494253 0.9375
43 NDG GAL 0.494253 0.9375
44 NLC 0.494253 0.9375
45 NGA GLA GAL BGC 0.49 0.9375
46 NGA GAL BGC 0.489362 0.9375
47 MAN BMA MAN MAN MAN 0.48913 0.6875
48 M5S 0.48913 0.6875
49 GAL NAG GAL FUC 0.485149 0.958333
50 GLA NAG GAL FUC 0.485149 0.958333
51 GLC GLC GLC GLC GLC GLC 0.483516 0.6875
52 NAG GAL 0.483146 0.9375
53 NGA GAL 0.483146 0.9375
54 GAL NAG 0.483146 0.9375
55 AML MAN MAN MAN MAN MAN MAN MAN MAN 0.481132 0.62963
56 NAG MAN MMA 0.479167 0.938776
57 NAG GAL GAL 0.478723 0.9375
58 MAN BMA NAG 0.478723 0.9375
59 GLA GAL NAG 0.478723 0.9375
60 WZ4 0.478632 0.884615
61 NAG NAG NAG NAG NDG NAG 0.473118 0.979592
62 NAG NAG NAG NAG NAG 0.473118 0.979592
63 NAG NAG NAG NAG NAG NAG NAG NAG 0.473118 0.979592
64 NDG NAG NAG NDG 0.473118 0.979592
65 NDG NAG NAG 0.473118 0.979592
66 CTO 0.473118 0.979592
67 NDG NAG NAG NDG NAG 0.473118 0.979592
68 NAG NAG NDG 0.473118 0.979592
69 NAG NAG NAG NAG 0.473118 0.979592
70 NDG NAG NAG NAG 0.473118 0.979592
71 NAG NAG NAG NAG NDG 0.473118 0.979592
72 NAG NAG NAG 0.473118 0.979592
73 NAG NAG NAG NDG 0.473118 0.979592
74 NAG NAG NAG NAG NAG NAG 0.473118 0.979592
75 FUC GAL NAG GAL BGC 0.472222 0.958333
76 BGC BGC GLC 0.471264 0.6875
77 GAL NGA GLA BGC GAL 0.470588 0.9375
78 NAG GAL BGC 0.469388 0.9375
79 MAN MAN NAG 0.469388 0.9
80 BGC GAL NAG GAL FUC FUC 0.468468 0.938776
81 GLC GAL NAG GAL FUC FUC 0.468468 0.938776
82 SIA GAL NAG GAL 0.467213 0.90566
83 GAL NAG SIA GAL 0.467213 0.90566
84 NAG BMA MAN MAN MAN MAN MAN 0.465347 0.686275
85 FUC GAL NAG 0.463918 0.958333
86 DR2 0.463918 0.958333
87 FUL GAL NAG 0.463918 0.958333
88 NDG GAL FUC 0.463918 0.958333
89 FUC GAL NDG 0.463918 0.958333
90 8VZ 0.460674 0.979592
91 BGC GAL NAG GAL 0.46 0.9375
92 LAT NAG GAL 0.46 0.9375
93 GAL NAG GAL BGC 0.46 0.9375
94 NAG GAL NAG 0.454545 1
95 NAG NAG BMA BMA 0.438095 0.888889
96 CTO TMX 0.435644 0.827586
97 TCG 0.435644 0.827586
98 MAN MAN BMA MAN 0.431579 0.6875
99 MAN MAN MAN MAN 0.431579 0.6875
100 A2G GAL BGC FUC 0.431193 0.958333
101 CBS 0.430108 1
102 CBS CBS 0.430108 1
103 NAG GDL 0.430108 1
104 NAG NDG 0.430108 1
105 NAG GAL FUC 0.43 0.958333
106 DR3 0.43 0.958333
107 A2G GAL 0.428571 0.9375
108 GAL A2G 0.428571 0.9375
109 M3M 0.428571 0.6875
110 MAN GLC 0.428571 0.6875
111 GAL NGA 0.428571 0.9375
112 LB2 0.428571 0.6875
113 SIA GAL NAG GAL GLC 0.427481 0.90566
114 SIA GAL NAG GAL BGC 0.427481 0.90566
115 BGC GAL NAG SIA GAL 0.427481 0.90566
116 ACY 1GN GAL 1GN BGC ACY GAL BGC 0.427273 1
117 1GN ACY GAL ACY 1GN BGC GAL BGC 0.427273 1
118 GLC GLC GLC BGC 0.427083 0.6875
119 GLA GAL NAG FUC GAL GLC 0.426087 0.958333
120 FUC BGC GAL NAG 0.425926 0.958333
121 A2G MBG 0.425532 0.938776
122 MBG A2G 0.425532 0.938776
123 NOJ NAG NAG 0.423077 0.888889
124 NOJ NAG NAG NAG 0.423077 0.872727
125 GLC FUC GAL FUC A2G 0.422018 0.938776
126 3PV 0.422018 0.884615
127 BGC FUC GAL FUC A2G 0.422018 0.938776
128 BDZ 0.421569 0.938776
129 GAL NAG FUC FUC 0.421569 0.938776
130 FUC GAL NDG FUC 0.421569 0.938776
131 GAL NDG FUC FUC 0.421569 0.938776
132 FUC NAG GAL FUC 0.421569 0.938776
133 FUC GAL NAG FUC 0.421569 0.938776
134 FUC NDG GAL FUC 0.421569 0.938776
135 BCW 0.421569 0.938776
136 NAG NAG NAG NAG NAG NAG NAG 0.420561 0.888889
137 A2G GAL NAG FUC GAL GLC 0.420168 0.979592
138 GLC GAL NAG GAL FUC A2G 0.420168 0.979592
139 G6S NAG 0.42 0.725806
140 A2G GAL NAG FUC 0.418182 0.979592
141 MAN MAN BMA 0.41573 0.6875
142 NAG BMA 0.414894 0.846154
143 FUC GAL NAG A2G 0.414414 0.888889
144 NAG NAG NGT 0.411215 0.813559
145 MAN MAN MAN GLC 0.410526 0.6875
146 BGC GLC GLC 0.409091 0.6875
147 GLC BGC BGC BGC BGC BGC 0.409091 0.6875
148 CTT 0.409091 0.6875
149 GAL GAL GAL 0.409091 0.6875
150 CTR 0.409091 0.6875
151 BGC BGC BGC GLC 0.409091 0.6875
152 BGC GLC GLC GLC GLC GLC GLC 0.409091 0.6875
153 GLC GLC BGC 0.409091 0.6875
154 BGC BGC BGC BGC BGC BGC 0.409091 0.6875
155 BMA MAN BMA 0.409091 0.6875
156 BMA BMA BMA 0.409091 0.6875
157 DXI 0.409091 0.6875
158 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.409091 0.6875
159 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.409091 0.6875
160 CE5 0.409091 0.6875
161 BGC GLC GLC GLC GLC 0.409091 0.6875
162 MAN MAN BMA BMA BMA BMA 0.409091 0.6875
163 GLC GAL GAL 0.409091 0.6875
164 MAN BMA BMA BMA BMA 0.409091 0.6875
165 CE6 0.409091 0.6875
166 GLC GLC GLC GLC GLC GLC GLC 0.409091 0.6875
167 B4G 0.409091 0.6875
168 BMA BMA BMA BMA BMA 0.409091 0.6875
169 CEX 0.409091 0.6875
170 GLC GLC GLC GLC GLC 0.409091 0.6875
171 NBG BGC BGC XYS BGC XYS XYS 0.409091 0.9
172 GLC GLC BGC GLC GLC GLC GLC 0.409091 0.6875
173 CE8 0.409091 0.6875
174 MT7 0.409091 0.6875
175 GLA GAL GLC 0.409091 0.6875
176 BGC GLC GLC GLC 0.409091 0.6875
177 GLC BGC GLC 0.409091 0.6875
178 CT3 0.409091 0.6875
179 MAN BMA BMA 0.409091 0.6875
180 GLC BGC BGC BGC BGC 0.409091 0.6875
181 BMA BMA BMA BMA BMA BMA 0.409091 0.6875
182 CEY 0.409091 0.6875
183 MLR 0.409091 0.6875
184 GLC BGC BGC 0.409091 0.6875
185 GLC GLC GLC GLC GLC GLC GLC GLC 0.409091 0.6875
186 MTT 0.409091 0.6875
187 MAN NAG 0.408602 0.9375
188 BMA BMA GLA BMA BMA 0.408163 0.6875
189 FUC GAL GLC 0.40625 0.708333
190 LAT FUC 0.40625 0.708333
191 FUC LAT 0.40625 0.708333
192 BGC GAL FUC 0.40625 0.708333
193 GLC GAL FUC 0.40625 0.708333
194 GAL BGC BGC XYS 0.405941 0.66
195 GLA EGA 0.404494 0.693878
196 BGC BGC BGC BGC BGC 0.404494 0.6875
197 GLC BGC BGC BGC 0.404494 0.6875
198 BGC BGC BGC GLC BGC BGC 0.404494 0.6875
199 GLC BGC BGC BGC BGC BGC BGC 0.404494 0.6875
200 BGC BGC BGC ASO BGC BGC ASO 0.404494 0.6875
201 BGC BGC BGC 0.404494 0.6875
202 6PZ ACY ACY BGC GAL 1GN 1GN ACY GAL GAL ACY BGC 0.402878 0.888889
203 ACY ACY 6PZ BGC GAL 1GN ACY 1GN GAL GAL ACY BGC 0.402878 0.888889
204 A2G GAL FUC 0.401961 0.958333
205 A2G GLA FUC 0.401961 0.958333
206 FUC GLA A2G 0.401961 0.958333
207 FUC GAL A2G 0.401961 0.958333
208 NGA GAL FUC 0.401961 0.958333
209 FUC GL0 A2G 0.401961 0.958333
210 BGC BGC BGC BGC 0.4 0.6875
211 BGC BGC BGC BGC BGC BGC BGC BGC 0.4 0.6875
212 6PZ BGC GAL 1GN 1GN ACY GAL GAL ACY BGC 0.4 0.888889
213 NAG AMU NAG AMV 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1SLT; Ligand: NDG GAL; Similar sites found: 98
This union binding pocket(no: 1) in the query (biounit: 1slt.bio3) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1KQW RTL 0.001986 0.46346 None
2 3MTX PGT 0.00522 0.44485 None
3 1KGI T4A 0.01062 0.4193 None
4 1VYF OLA 0.017 0.41847 None
5 2QZT PLM 0.025 0.41415 None
6 5JKG 6LF 0.02084 0.41091 None
7 5J8O 6GZ 0.02059 0.40841 None
8 4QM9 CYS 0.002818 0.4043 None
9 3ZO7 K6H 0.009189 0.4039 None
10 1X0P FAD 0.01799 0.40365 None
11 5C8W PCG 0.02264 0.40257 None
12 2BOS GLA GAL GLC 0.001884 0.40179 None
13 3JRS A8S 0.01183 0.41636 1.44231
14 5FL5 82E 0.008385 0.40032 1.49254
15 4MP8 NAD 0.01168 0.4434 2.23881
16 5JSP DQY 0.002027 0.4039 2.23881
17 5BV6 35G 0.02309 0.41471 2.98507
18 3W7T BMA 0.0188 0.40243 2.98507
19 3G08 FEE 0.006088 0.47634 3.0303
20 4KYS VIB 0.00146 0.4515 3.73134
21 5A65 TPP 0.008105 0.41968 3.73134
22 3TYZ PAB 0.02173 0.4145 3.73134
23 4GCZ FMN 0.01107 0.41389 3.73134
24 2BMB PMM 0.01619 0.40667 3.73134
25 4KAX 4IP 0.008667 0.40465 3.73134
26 4D1J DGJ 0.003203 0.40233 3.73134
27 1UMZ BGC BGC XYS BGC XYS GAL 0.00005398 0.44091 4.47761
28 3H22 B53 0.007771 0.42264 4.47761
29 3NW7 LGV 0.02085 0.42146 4.47761
30 3N9Q OGA 0.001887 0.41093 4.47761
31 3N9O OGA 0.002027 0.40967 4.47761
32 1GP6 SIN 0.03651 0.40378 4.47761
33 1GP6 QUE 0.03846 0.40378 4.47761
34 4G7A AZM 0.003698 0.4208 4.83871
35 3PQB VGP 0.006755 0.43368 5.22388
36 2Q0D ATP 0.01761 0.42374 5.22388
37 4B7P 9UN 0.04296 0.40877 5.22388
38 5HV0 AKG 0.009527 0.40869 5.22388
39 3Q8G PEE 0.03545 0.40766 5.22388
40 1M0W ANP 0.01581 0.40381 5.22388
41 3VOT ADP 0.02426 0.40018 5.22388
42 2XMY CDK 0.001731 0.50224 5.97015
43 2R09 4IP 0.004214 0.42251 5.97015
44 4O1P ANP 0.01462 0.41446 5.97015
45 4USF 6UI 0.01529 0.41438 5.97015
46 2I74 MAN MAN MAN MAN 0.00158 0.40855 5.97015
47 4QDC ASD 0.01009 0.40757 5.97015
48 5H9Y BGC BGC BGC BGC 0.009813 0.40489 5.97015
49 3VPD ANP 0.02187 0.40369 5.97015
50 5HES 032 0.02282 0.40334 5.97015
51 5VNF VAL THR SER VAL VAL 0.001712 0.44049 6.71642
52 5BX3 NOJ 0.005031 0.43304 6.71642
53 1NE6 SP1 0.01147 0.4193 6.71642
54 4TWL ASC 0.0053 0.41777 6.71642
55 2Q4H AMP 0.01951 0.41249 6.71642
56 5VGS 9A4 0.006442 0.40518 6.71642
57 5VGS 9A7 0.007379 0.40518 6.71642
58 4IGQ THR M3L GLN 0.01559 0.40279 6.71642
59 3BXO UPP 0.02612 0.40152 6.71642
60 4HIA FMN 0.009892 0.43332 6.81818
61 3AGC RCC 0.01702 0.42463 7.24638
62 4K55 H6P 0.004907 0.40413 7.25806
63 5EOB 5QQ 0.01032 0.446 7.46269
64 3S7O LBV 0.02869 0.41606 7.46269
65 3LVW GSH 0.01464 0.41336 7.46269
66 4Q0L V14 0.01733 0.40766 7.46269
67 4IGH FMN 0.002547 0.4859 8.20895
68 4IGH ORO 0.002547 0.4859 8.20895
69 4IGH 1EA 0.002547 0.4859 8.20895
70 1URX AAL GAL AAL GLA 0.0163 0.40566 8.20895
71 1DMY AZM 0.007413 0.40432 8.20895
72 4X5S AZM 0.003654 0.40092 8.20895
73 3FW4 CAQ 0.008914 0.41746 8.95522
74 5H2D ERG 0.02693 0.40509 8.95522
75 4DE9 VTP 0.005715 0.44955 9.70149
76 4COQ SAN 0.003339 0.40188 9.70149
77 3MF2 AMP 0.003476 0.45438 10.4478
78 4H2V AMP 0.003631 0.45112 10.4478
79 1ZNY GDP 0.004521 0.42676 10.4478
80 1XNK XS2 0.006187 0.41386 10.4478
81 1M15 ADP 0.03066 0.40405 10.4478
82 1M15 ARG 0.03066 0.40405 10.4478
83 1ZM1 BGC BGC BGC 0.002325 0.44295 11.194
84 4QRH 0O2 0.006025 0.43854 11.194
85 5LRT ADP 0.01325 0.41826 11.194
86 3JU6 ANP 0.005675 0.41533 11.194
87 4CLI 5P8 0.04465 0.40198 11.194
88 1EM6 CP4 0.03503 0.44126 11.9403
89 3VQ2 LP4 LP5 MYR DAO 0.01065 0.43143 12.6866
90 4MLO PAM 0.00269 0.44724 13.4328
91 1J3R 6PG 0.009577 0.40623 14.1791
92 3KA2 2NC 0.02417 0.41077 14.9254
93 1I82 BGC BGC 0.0004879 0.42742 15.6716
94 3QRC SCR 0.00006207 0.48877 16.4179
95 1GQG DCD 0.01111 0.41794 18.6567
96 3M3E GAL A2G NPO 0.00000004883 0.66538 22.3881
97 1QKQ MAN 0.00000002094 0.7028 32.0896
98 3VV1 GAL FUC 0.000000001508 0.75289 35.0746
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