-->
Receptor
PDB id Resolution Class Description Source Keywords
1SG9 2.3 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA PROTEIN HEMK, AN N5-GLUTAMINE METHYLTRANSFERASE THERMOTOGA MARITIMA STRUCTURAL GENOMICS PROTEIN STRUCTURE INITIATIVE HEMK PROTEIN HYPOTHETICAL PROTEIN PSI NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS NYSGXRC UNKNOWN FUNCTION
Ref.: A NOVEL MODE OF DIMERIZATION VIA FORMATION OF A GLUTAMATE ANHYDRIDE CROSSLINK IN A PROTEIN CRYSTAL STRUCTURE. PROTEINS V. 71 1038 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GLN A:400;
B:401;
C:402;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
146.144 C5 H10 N2 O3 C(CC(...
SAM A:301;
B:302;
C:303;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1NV8 2.2 Å EC: 2.1.1.- N5-GLUTAMINE METHYLTRANSFERASE, HEMK THERMOTOGA MARITIMA CLASS I ADOMET-DEPENDENT METHYLTRANSFERASE TRANSFERASE
Ref.: STRUCTURES ALONG THE CATALYTIC PATHWAY OF PRMC/HEMK N(5)-GLUTAMINE ADOMET-DEPENDENT METHYLTRANSFERASE BIOCHEMISTRY V. 42 5592 2003
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 1NV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1SG9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 1NV9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 1NV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1SG9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 1NV9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 1NV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1SG9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 1NV9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GLN; Similar ligands found: 34
No: Ligand ECFP6 Tc MDL keys Tc
1 GLN 1 1
2 DGN 1 1
3 GGL 0.62963 0.821429
4 GLU 0.62963 0.821429
5 DGL 0.62963 0.821429
6 ONL 0.586207 0.741935
7 HGA 0.53125 0.75
8 DAB 0.518519 0.65625
9 HSE 0.518519 0.6875
10 MEQ 0.515152 0.870968
11 API 0.5 0.793103
12 NVA 0.5 0.666667
13 HCS 0.5 0.645161
14 ASN 0.481481 0.833333
15 UN1 0.46875 0.793103
16 11C 0.46875 0.793103
17 ABA 0.461538 0.62069
18 DBB 0.461538 0.62069
19 ORN 0.451613 0.677419
20 C2N 0.444444 0.6
21 NPI 0.441176 0.766667
22 NLE 0.4375 0.625
23 26P 0.428571 0.71875
24 ASP 0.428571 0.7
25 DAS 0.428571 0.7
26 3GC 0.425 0.794118
27 DLY 0.424242 0.65625
28 DHH 0.411765 0.709677
29 LYS 0.411765 0.636364
30 BGT 0.405405 0.685714
31 2NP 0.405405 0.611111
32 AS2 0.4 0.75
33 3O3 0.4 0.666667
34 ONH 0.4 0.605263
Ligand no: 2; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1NV8; Ligand: MEQ; Similar sites found with APoc: 727
This union binding pocket(no: 1) in the query (biounit: 1nv8.bio1) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 1P1C SAH None
2 2WG9 OCA None
3 1M2K APR 0.803213
4 3QJ4 FAD 1.05634
5 1UAY ADN 1.23967
6 2PXX SAH 1.39535
7 4RDH AMP 1.40845
8 4RDI ATP 1.40845
9 3ITJ CIT 1.40845
10 4EMI NAD 1.40845
11 3ITJ FAD 1.40845
12 4D79 ATP 1.44928
13 4JK3 NAD 1.5444
14 4J4H 1J1 1.5444
15 4J4H NAI 1.5444
16 3VSE SAH 1.76056
17 2A92 NAI 1.76056
18 5TTJ FAD 1.76056
19 4C3Y FAD 1.76056
20 4C3Y ANB 1.76056
21 4GKV NAD 1.76056
22 1TDF FAD 1.76056
23 4TQG NDP 1.76056
24 1P77 ATR 1.83824
25 5UFN SAH 2.10084
26 3ELW SAM 2.11268
27 3ELW GP3 2.11268
28 5J5Z FAD 2.11268
29 5U8U FAD 2.11268
30 2F5Z FAD 2.11268
31 5MBX SP5 2.11268
32 5MBX FAD 2.11268
33 3C6K SPD 2.11268
34 3C6K MTA 2.11268
35 3MCT SAH 2.11268
36 2OBF SAH 2.11268
37 2OBF F83 2.11268
38 2B9W FAD 2.11268
39 2XVE FAD 2.11268
40 1XHC FAD 2.11268
41 4CNK FAD 2.11268
42 6A20 ADP 2.11268
43 3MAG SAH 2.11268
44 3FXU TSU 2.11268
45 3HQP FDP 2.11268
46 4YKG NAD 2.11268
47 1KOL NAD 2.11268
48 4YKG FAD 2.11268
49 3LCV SAM 2.13523
50 5ZXD ATP 2.1978
51 2EJU SAH 2.46479
52 1BW9 NAD 2.46479
53 4M52 FAD 2.46479
54 5W7M SAH 2.46479
55 4M52 M52 2.46479
56 3HDY GDU 2.46479
57 3HDY FDA 2.46479
58 2A8X FAD 2.46479
59 1QO8 FAD 2.46479
60 2YYY NAP 2.46479
61 2NVK FAD 2.46479
62 3HDY FAD 2.46479
63 4OPC FDA 2.46479
64 4OPC PGT 2.46479
65 5JJR SAH 2.46479
66 2VHW NAI 2.46479
67 3ZG6 APR 2.46479
68 1OMO NAD 2.46479
69 1X7D ORN 2.46479
70 3DAG FEG 2.46479
71 1X7D NAD 2.46479
72 1BXG HCI 2.46479
73 6F7L FAD 2.46479
74 1RYI FAD 2.46479
75 1RYI GOA 2.46479
76 1C1D PHE 2.46479
77 1K0E TRP 2.46479
78 1BXG NAD 2.46479
79 5XLX SAH 2.48227
80 3EVF GTA 2.52708
81 3EVF SAH 2.52708
82 5CUQ NSC 2.62172
83 3P2E SAH 2.66667
84 3GJ8 GDP 2.71493
85 3GJ0 GDP 2.71493
86 1L1E SAH 2.8169
87 1V59 NAD 2.8169
88 1SQF SAM 2.8169
89 1V59 FAD 2.8169
90 2XT3 ADP 2.8169
91 1Q9I FAD 2.8169
92 1Q9I TEO 2.8169
93 3VYW SAM 2.8169
94 4ZCC NAI 2.8169
95 4ZCC FAD 2.8169
96 3B6R CRN 2.8169
97 5GSN MMZ 2.8169
98 1UXG FUM 2.8169
99 1UXG NAD 2.8169
100 1DJN ADP 2.8169
101 5GSN NAP 2.8169
102 5GSN FAD 2.8169
103 2Q7V FAD 2.8169
104 2NPX NAD 2.8169
105 3LXD FAD 2.8169
106 2NPX FAD 2.8169
107 5A1S FLC 2.8169
108 6F97 FAD 2.8169
109 1H2B NAJ 2.8169
110 3O9Z AKG 2.8169
111 4D5G FAD 2.8169
112 4D5G TPP 2.8169
113 2R4J FAD 2.8169
114 2R4J 13P 2.8169
115 3GD4 FAD 2.8169
116 3GD4 NAD 2.8169
117 4UP4 GAL NAG 2.8169
118 3O9Z NAD 2.8169
119 1HE1 AF3 2.84091
120 2DT5 NAD 2.8436
121 5L4R CPT 2.89855
122 2WA2 SAM 2.89855
123 4TXI FAD 2.92683
124 1MVQ MMA 2.9661
125 2EB5 OXL 2.99625
126 5N5D SAM 3.09735
127 6DUB SAH 3.15315
128 1PJS NAD 3.16901
129 2CDU ADP 3.16901
130 3L9W AMP 3.16901
131 3L9W GSH 3.16901
132 5Y8L NAD 3.16901
133 5Y8L HUI 3.16901
134 1H82 FAD 3.16901
135 1SC6 NAD 3.16901
136 1H82 GZZ 3.16901
137 2CDU FAD 3.16901
138 4RPL 3UC 3.16901
139 4RPL FAD 3.16901
140 3U31 NAD 3.16901
141 1MUU NAD 3.16901
142 2GV8 FAD 3.16901
143 2GVC FAD 3.16901
144 1VKO NAD 3.16901
145 3G5S FAD 3.16901
146 6AA8 NAD 3.16901
147 1VQW FAD 3.16901
148 4A6D SAM 3.16901
149 1VC9 ATP 3.1746
150 1VBO MAN 3.3557
151 1VBO MAN MAN MAN 3.3557
152 1ZGA SAH 3.36134
153 1JJV ATP 3.39806
154 2AG8 NAP 3.42205
155 3RKR NAP 3.43511
156 3N8K D1X 3.48837
157 4POO SAM 3.5
158 4AZW SAM 3.52113
159 1U2Z SAH 3.52113
160 5YF1 8V0 3.52113
161 1DLJ NAI 3.52113
162 4YAC NAI 3.52113
163 3OA2 NAD 3.52113
164 1MV8 NAD 3.52113
165 3KLJ FAD 3.52113
166 4JNA FAD 3.52113
167 5N6C NAD 3.52113
168 5YF1 SFG 3.52113
169 1RZM E4P 3.52113
170 3VPH NAD 3.52113
171 4TM3 FAD 3.52113
172 2XVF FAD 3.52113
173 3VPH OXM 3.52113
174 1DLJ UGA 3.52113
175 4BV6 FAD 3.52113
176 3K7M FAD 3.52113
177 1HYH NAD 3.52113
178 1FP1 SAH 3.52113
179 5OC1 FAD 3.52113
180 5YRG BGC GLC 3.52113
181 1U1I NAD 3.52113
182 2G50 ALA 3.52113
183 5J60 FAD 3.52113
184 2CYC TYR 3.52113
185 4L2I FAD 3.52113
186 5J7X FAD 3.52113
187 2YVF NAD 3.52113
188 4E13 NAD 3.53357
189 1XTP SAI 3.54331
190 4KXQ APR 3.55872
191 2BRY FAD 3.62173
192 3WV8 ATP 3.66972
193 2VT3 ATP 3.72093
194 2FMD MAN MAN 3.75
195 3BGD PM6 3.84615
196 3BGD SAH 3.84615
197 1Q0S SAH 3.861
198 5THZ SAH 3.87324
199 1FP2 SAH 3.87324
200 1VJT NAD 3.87324
201 5THY SAH 3.87324
202 5YJI SAH 3.87324
203 5YJI 8WO 3.87324
204 1RP0 AHZ 3.87324
205 5T67 JHZ 3.87324
206 4GUS FAD 3.87324
207 4FWE FAD 3.87324
208 4GUT FAD 3.87324
209 4HSU FAD 3.87324
210 4LIK CIT 3.87324
211 5JGL SAM 3.87324
212 5T67 SAH 3.87324
213 2RGO FAD 3.87324
214 1V6A TRE 3.87324
215 1YBH FAD 3.87324
216 1V8K ANP 3.87324
217 2NU8 COA 3.87324
218 3BP1 GUN 3.87324
219 1RM0 NAI 3.87324
220 1RM0 D6P 3.87324
221 3JQ7 DX2 3.87324
222 3JQ9 AX1 3.87324
223 4WCX ALA 3.87324
224 6CEP OXM 3.87324
225 6CEP NAD 3.87324
226 5MZI FYK 3.87324
227 5MZI FAD 3.87324
228 4E5N NAD 3.87324
229 2O7B HC4 3.87324
230 5NMX FAD 3.87324
231 5NMX NAP 3.87324
232 5Y77 FAD 3.87324
233 3JQG AX6 3.87324
234 3B1F NAD 3.87324
235 1I9G SAM 3.92857
236 2F1K NAP 3.94265
237 1VE3 SAM 3.96476
238 3FPZ AHZ 3.98773
239 2HK9 ATR 4
240 4QM7 GTP 4.09357
241 5BW4 SAM 4.11985
242 5I39 FAD 4.16667
243 4BLW AMP 4.22535
244 4BLW SAH 4.22535
245 4M3P HCS 4.22535
246 4PLG OXM 4.22535
247 4PLG NAI 4.22535
248 3COB ADP 4.22535
249 1REO FAD 4.22535
250 5ZYN FAD 4.22535
251 2JHP SAH 4.22535
252 1GTE FAD 4.22535
253 3QPB URA 4.22535
254 5W7R SAH 4.22535
255 6GAR FAD 4.22535
256 5TOW NAI 4.22535
257 5TOW ADN 4.22535
258 5YAP NAI 4.22535
259 3F8D FAD 4.22535
260 4MOP 2H5 4.22535
261 5Z20 NAI 4.22535
262 3A4M ADP 4.23077
263 2HJR APR 4.26829
264 1I1N SAH 4.42478
265 1TE2 PGA 4.42478
266 1JQ3 AAT 4.57746
267 6ECU SAH 4.57746
268 2IXB A2G 4.57746
269 1X87 NAD 4.57746
270 6ECW SAH 4.57746
271 4REP FAD 4.57746
272 2IVD FAD 4.57746
273 3C3Y SAH 4.57746
274 2BZG SAH 4.57746
275 4RVG TYD 4.57746
276 2IXB NAD 4.57746
277 1D4D FAD 4.57746
278 4RVG SAM 4.57746
279 2RAB FAD 4.57746
280 2RAB NAD 4.57746
281 4IV9 FAD 4.57746
282 1WDK NAD 4.57746
283 5JCM NAD 4.57746
284 5JCM ISD 4.57746
285 5JCM FAD 4.57746
286 1SZ2 BGC 4.57746
287 3T31 DCQ 4.57746
288 3T31 FAD 4.57746
289 4C91 REL 4.57746
290 1GPE FAD 4.57746
291 1GV0 NAD 4.57746
292 4XUC 43G 4.58716
293 4XUC SAM 4.58716
294 2G5C NAD 4.62633
295 3CTY FAD 4.70219
296 5D4V SAH 4.85075
297 1Y63 ADP 4.8913
298 5XNC MTA 4.92958
299 3QOX SAH 4.92958
300 2ZFU SAH 4.92958
301 1T26 GBD 4.92958
302 1T26 NAI 4.92958
303 2BHZ MAL 4.92958
304 2Z3Y F2N 4.92958
305 1Y8Q ATP 4.92958
306 2HQM FAD 4.92958
307 1E1M FAD 4.92958
308 1E1M NAP 4.92958
309 5KOK SAH 4.92958
310 4U8P FDA 4.92958
311 4JDR FAD 4.92958
312 1P31 EPU 4.92958
313 2VVM FAD 4.92958
314 4U8P UDP 4.92958
315 5KOK S9T 4.92958
316 3LZW FAD 4.92958
317 5UAV TFB 4.92958
318 4TQK NAG 4.92958
319 6C4N NAP 4.92958
320 5UAV NDP 4.92958
321 3LZW NAP 4.92958
322 5ICE 2H4 4.92958
323 5ICE SAH 4.92958
324 5KOK R9T 4.92958
325 4DSG UDP 4.92958
326 4DSG FAD 4.92958
327 2NAD NAD 4.92958
328 5O4J 9KH 5.10949
329 5O4J SAH 5.10949
330 5O4J PJL 5.10949
331 5N53 8NB 5.12821
332 1KO8 6PG 5.14286
333 5FA5 MTA 5.28169
334 4GQB 0XU 5.28169
335 3PT9 SAH 5.28169
336 2ZIF SAM 5.28169
337 2IID PHE 5.28169
338 2IID FAD 5.28169
339 3OND NAD 5.28169
340 3OND ADN 5.28169
341 5M67 NAD 5.28169
342 5M67 ADE 5.28169
343 5YJF 8WO 5.28169
344 2GAG NAD 5.28169
345 5M67 3D1 5.28169
346 2Q0L NAP 5.28169
347 5Z21 NAI 5.28169
348 1F8G NAD 5.28169
349 5YJF SAH 5.28169
350 1KGZ PRP 5.28169
351 3NTA FAD 5.28169
352 2GAG FOA 5.28169
353 5BJX UDP 5.28169
354 5BJX NAD 5.28169
355 3NT6 FAD 5.28169
356 4CS9 AMP 5.29101
357 5MLJ 9ST 5.35714
358 1G60 SAM 5.38462
359 2AOT SAH 5.47945
360 2YVJ NAI 5.50459
361 5EIN NAP 5.55556
362 5ULP KB1 5.59701
363 5DNK SAH 5.6338
364 2DPM SAM 5.6338
365 3NJ4 NAD 5.6338
366 1JQD SAH 5.6338
367 3NJ4 AFX 5.6338
368 6FP4 FAD 5.6338
369 5EZ7 FAD 5.6338
370 6F3M NAD 5.6338
371 1PN0 FAD 5.6338
372 6F3N NAD 5.6338
373 6F3N ADN 5.6338
374 1PN0 IPH 5.6338
375 6FP4 E1T 5.6338
376 3GGO ENO 5.6338
377 3GGO NAI 5.6338
378 2P41 SAH 5.6338
379 3NTD FAD 5.6338
380 1JQD HSM 5.6338
381 5HTX ADP 5.6338
382 5E1M SAH 5.80913
383 5E1M PRO PRO LYS ARG ILE ALA 5.80913
384 1KYQ NAD 5.83942
385 3TKA SAM 5.98592
386 6BQ6 TER 5.98592
387 4AP3 FAD 5.98592
388 4AP3 NAP 5.98592
389 1BZL FAD 5.98592
390 1BZL GCG 5.98592
391 2WPF FAD 5.98592
392 1ZK7 FAD 5.98592
393 1RSG FAD 5.98592
394 2WPF WPF 5.98592
395 3OBT SLB 5.98592
396 1LVL NAD 5.98592
397 3UCL CYH 5.98592
398 3UCL NAP 5.98592
399 3UCL FAD 5.98592
400 1V8B NAD 5.98592
401 4NTD FAD 5.98592
402 5VN0 FAD 5.98592
403 4XFR CIT 5.98592
404 5VN0 NAI 5.98592
405 4KOA NDP 5.98592
406 4Z24 FAD 5.98592
407 1KYZ SAH 5.98592
408 1I36 NAP 6.06061
409 4XZ3 COA 6.08696
410 6EQS BV8 6.18182
411 2IZ1 ATR 6.33803
412 4PIO SAH 6.33803
413 3G2O SAM 6.33803
414 4PIO AVI 6.33803
415 1YY5 FAD 6.33803
416 5W7K SAH 6.33803
417 3WLE NAD 6.33803
418 1YQZ FAD 6.33803
419 2E5V FAD 6.33803
420 3OJO NAD 6.33803
421 3GDN HBX 6.33803
422 3GDN FAD 6.33803
423 4KGD FAD 6.33803
424 4KGD TDP 6.33803
425 5BSZ SAH 6.4
426 1LSS NAD 6.42857
427 4RDN 6MD 6.58683
428 4PLT NAI 6.64653
429 4PLT OXM 6.64653
430 5TQZ GLC 6.66667
431 5X2N ALA 6.66667
432 4LWP SAH 6.69014
433 5HJM MTA 6.69014
434 4YUW S4M 6.69014
435 4YUW 4JU 6.69014
436 1Z3C SA8 6.69014
437 4RSL FAD 6.69014
438 1J49 NAD 6.69014
439 2Z48 A2G 6.69014
440 4J56 FAD 6.69014
441 6A3J SOE 6.69014
442 3GCZ SAM 6.73759
443 1XCL SAH 6.80851
444 3H8V ATP 6.84932
445 5K7U SAM 6.87679
446 3FPF TNA 7.04225
447 3FPF MTA 7.04225
448 2XVM SAH 7.04225
449 3GFB NAD 7.04225
450 5TWB FAD 7.04225
451 2YG3 FAD 7.04225
452 4B63 NAP 7.04225
453 4B63 FAD 7.04225
454 4B63 ORN 7.04225
455 1A5Z NAD 7.04225
456 3CGD FAD 7.04225
457 3CGD NAD 7.04225
458 5E9W SAH 7.04225
459 3CGD COA 7.04225
460 2PX8 SAH 7.0632
461 5L95 AMP 7.16846
462 1O94 ADP 7.19697
463 1KHT AMP 7.29167
464 4CQM NAP 7.37705
465 2YX1 SFG 7.39437
466 3TKY SAH 7.39437
467 4XQC 13D 7.39437
468 4XQC NAD 7.39437
469 1ZH8 NAP 7.39437
470 3S5W FAD 7.39437
471 4JJF FE9 7.39437
472 4JJF N2I 7.39437
473 1LDN NAD 7.39437
474 6FHO FAD 7.39437
475 6GAS FAD 7.39437
476 1PS9 FAD 7.39437
477 5FTW SAH 7.42188
478 2JE7 XMM 7.53138
479 2HMT NAI 7.63889
480 3S1S SAH 7.74648
481 4OM8 NAD 7.74648
482 4PNE SAH 7.74648
483 1PL6 NAD 7.74648
484 4G5H UD7 7.74648
485 4G5H NAP 7.74648
486 5DN9 NAD 7.74648
487 6B3A SAM 7.74648
488 2QA1 FAD 7.74648
489 1COY FAD 7.74648
490 1V5F TPP 7.74648
491 1V5F FAD 7.74648
492 4UCI SAM 7.74648
493 2PWY SAH 7.75194
494 1F3L SAH 8.09859
495 2UYQ SAM 8.09859
496 5ODQ FAD 8.09859
497 5MPT SAH 8.09859
498 1GUZ NAD 8.09859
499 1KNR FAD 8.09859
500 5G3U FDA 8.09859
501 2C31 ADP 8.09859
502 2C31 TZD 8.09859
503 1NVM NAD 8.09859
504 5G3U ITW 8.09859
505 4RF7 ARG 8.09859
506 3ML1 MGD 8.09859
507 1XDS SAM 8.28877
508 5X62 SAH 8.4507
509 5ERG SAM 8.4507
510 1GET NAP 8.4507
511 1GET FAD 8.4507
512 9LDB NAD 8.4507
513 4ZVV NAD 8.4507
514 5JCA FAD 8.4507
515 4ZVV GN0 8.4507
516 5JCA NDP 8.4507
517 6GKV SAH 8.4507
518 3AB1 FAD 8.4507
519 2DFV NAD 8.4507
520 9LDT NAD 8.4507
521 4KRI SAH 8.80282
522 5F8F SFG 8.80282
523 2Q28 ADP 8.80282
524 3X0V FAD 8.80282
525 6C0B MLI 8.80282
526 3GF4 FAD 8.80282
527 3GF4 UPG 8.80282
528 1UP7 NAD 8.80282
529 2A14 SAH 8.80282
530 3K7S R52 8.93855
531 4JCA CIT 8.98204
532 3GWZ SAH 9.15493
533 3GXO SAH 9.15493
534 4E3Q PMP 9.15493
535 4WOE ADP 9.15493
536 4XB2 NDP 9.25373
537 5FWA J7C 9.50704
538 5FUB SAH 9.50704
539 5JE8 NAD 9.50704
540 5BVA FAD 9.50704
541 3AD8 NAD 9.50704
542 1R37 NAD 9.50704
543 2JB2 FAD 9.50704
544 2JB2 PHE 9.50704
545 1MO9 KPC 9.50704
546 1MO9 FAD 9.50704
547 3AD8 FAD 9.50704
548 3AD8 PYC 9.50704
549 1LTH NAD 9.50704
550 1MFI FHC 9.64912
551 3NYC IAR 9.71129
552 3NYC FAD 9.71129
553 1NW5 SAM 9.85915
554 5ZZ6 ADP 9.85915
555 1FEC FAD 9.85915
556 6C5B SAH 9.85915
557 3A27 SAM 9.85915
558 2GN4 UD1 9.85915
559 5ZZ6 NAD 9.85915
560 2GN4 NDP 9.85915
561 2VVL FAD 9.85915
562 1SOW NAD 9.85915
563 2XG5 EC2 9.85915
564 2XG5 EC5 9.85915
565 3DXY SAM 10.0917
566 1KPG SAH 10.2113
567 4Y9D NAI 10.2113
568 3ABI NAD 10.2113
569 4D7E FAD 10.2113
570 1ELI PYC 10.2113
571 5YB7 ORN 10.2113
572 5YB7 FAD 10.2113
573 3H2B SAH 10.3448
574 3MQ2 SAH 10.5505
575 1KPH SAH 10.5634
576 3LST SAH 10.5634
577 3UOY FAD 10.5634
578 3UOY NAP 10.5634
579 5YRL GLC GLC 10.5634
580 3Q3C NAD 10.5634
581 5YRJ BGC GLC 10.5634
582 5YRM BGC GLC 10.5634
583 1JNR FAD 10.5634
584 4IF4 BEF 10.5769
585 2GNB MAN 10.7143
586 1UKG MMA 10.7143
587 2GNM MAN 10.7143
588 1Q8V MAN MAN 10.7143
589 2GMM MAN MAN 10.7143
590 1Q8Q MAN MMA 10.7143
591 2PHX MAN MAN 10.7143
592 2GN3 MMA 10.7143
593 2PHT MAN MAN MAN 10.7143
594 2GN3 MAN 10.7143
595 2PHU MAN MAN 10.7143
596 2GND MAN 10.7143
597 1Q8S MAN MMA 10.7143
598 1Q8O MAN MMA 10.7143
599 2PHR MAN MAN 10.7143
600 2PHF MAN MAN 10.7143
601 1Q8P MAN MMA 10.7143
602 2PHW MAN MAN 10.7143
603 2GND MAN MMA 10.7143
604 2PHF MAN MAN BMA MAN 10.7143
605 2PHW MAN MAN MAN BMA MAN MAN MAN 10.7143
606 2PHR MAN MAN BMA MAN 10.7143
607 1G55 SAH 10.9155
608 1TPY SAH 10.9155
609 5GWX SAR 10.9155
610 5GWX SAM 10.9155
611 3LAD FAD 10.9155
612 5D63 FUC GLA GLA 10.9155
613 4YMH SAH 11.25
614 1QZZ SAM 11.2676
615 6ER9 FAD 11.2676
616 6ER9 NAP 11.2676
617 3EVG SAH 11.2676
618 4USQ FAD 11.2676
619 4OBW SAM 11.284
620 3BXO SAM 11.2971
621 6F5Z SAH 11.4754
622 6C8R SAH 11.6197
623 3T7S SAM 11.6197
624 2PT9 2MH 11.6197
625 3SQP FAD 11.6197
626 3PFG TLO 11.6197
627 3PFG SAM 11.6197
628 2PT9 S4M 11.6197
629 6C8R EQV 11.6197
630 2BOS GLA GAL GLC 11.7647
631 1U8Z GDP 11.9048
632 4KIB SAH 11.9718
633 5AHO TLA 11.9718
634 4YRY NAD 11.9718
635 4KRG SAH 11.9718
636 4YRY FAD 11.9718
637 1QAN SAH 12.2951
638 5TS5 FAD 12.3239
639 1BC5 SAH 12.3239
640 5A04 BGC 12.3239
641 5A04 NDP 12.3239
642 1SQL GUN 12.3288
643 4R6W PC 12.4031
644 4R6W SAH 12.4031
645 4NEC SAH 12.5
646 3FZG SAM 12.5
647 2I7C AAT 12.7208
648 1PZG A3D 12.9909
649 1RJW ETF 13.0282
650 1X14 NAD 13.0282
651 5FJN FAD 13.0282
652 5FJN BE2 13.0282
653 5UI2 SUC 13.0282
654 5JE0 AZ8 13.3603
655 5JE0 SAH 13.3603
656 3JWH SAH 13.3641
657 6ECT SAM 13.3803
658 5E72 SAM 13.7324
659 6ARJ BW4 13.7324
660 5DX0 SFG 13.7324
661 6ARJ SAH 13.7324
662 5DWQ SFG 13.7324
663 5DXA SFG 13.7324
664 5DX8 SFG 13.7324
665 5DX1 SFG 13.7324
666 3A25 SAM 13.7324
667 2FKA BEF 13.9535
668 3FGZ BEF 14.0625
669 1JG3 ADN 14.0845
670 1CF2 NAP 14.4366
671 1GR0 NAD 14.4366
672 6IS0 SAH 14.7887
673 3LKZ SFG 14.7887
674 2HNK SAH 15.0628
675 2C7G FAD 15.1408
676 2C7G ODP 15.1408
677 5BRT FAD 15.1408
678 5BRT CH9 15.1408
679 1OBB NAD 15.1408
680 3MB5 SAM 15.2941
681 1L3I SAH 15.625
682 2O07 SPD 15.8451
683 2O07 MTA 15.8451
684 4D04 FAD 15.8451
685 4D04 NAP 15.8451
686 5LOG SAH 15.8798
687 5MGZ SAH 16.1017
688 4DCM SAM 16.1972
689 5WP4 SAH 16.1972
690 5GM1 SAH 16.1972
691 6FDF SAH 16.1972
692 5YU3 PRO 16.5493
693 5YU3 NAD 16.5493
694 2ZXI FAD 16.5493
695 4N49 SAM 16.5493
696 2VDV SAM 16.6667
697 5FUI APY 16.6667
698 5U19 827 16.9014
699 5U19 SAH 16.9014
700 3RNM FAD 17.2414
701 3ICT ADP 17.2535
702 3ICS ADP 17.2535
703 3ICS FAD 17.2535
704 3ICT FAD 17.2535
705 3OU2 SAH 17.4312
706 5MW4 5JU 17.9577
707 5MIT FAD 17.9577
708 5MIT NAP 17.9577
709 4YT4 FE9 17.9577
710 5E8J SAH 18.1818
711 4II2 ATP 19.0184
712 3HVJ 705 19.7183
713 2ZJ1 ARJ 19.7183
714 2ZJ1 NAD 19.7183
715 3QFA FAD 19.8276
716 5FA8 SAM 19.8758
717 1E6E FAD 20.3125
718 4DMG SAM 20.8651
719 5KVA SAM 21.223
720 1DL5 SAH 22.1831
721 1UWK URO 22.8873
722 1UWK NAD 22.8873
723 3Q87 SAM 23.5294
724 6B92 SAH 23.9437
725 3IHG FAD 24.2958
726 1R18 SAH 25.9912
727 6GFK SAH 27.0916
Pocket No.: 2; Query (leader) PDB : 1NV8; Ligand: SAM; Similar sites found with APoc: 672
This union binding pocket(no: 2) in the query (biounit: 1nv8.bio1) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 1P1C SAH None
2 2WG9 OCA None
3 1M2K APR 0.803213
4 3QJ4 FAD 1.05634
5 1UAY ADN 1.23967
6 2PXX SAH 1.39535
7 4RDH AMP 1.40845
8 4RDI ATP 1.40845
9 4WEI GLC GAL 1.44404
10 4D79 ATP 1.44928
11 4JK3 NAD 1.5444
12 4J4H 1J1 1.5444
13 4J4H NAI 1.5444
14 3VSE SAH 1.76056
15 2A92 NAI 1.76056
16 5TTJ FAD 1.76056
17 4C3Y FAD 1.76056
18 4C3Y ANB 1.76056
19 4GKV NAD 1.76056
20 1P77 ATR 1.83824
21 5NM7 GLY 1.8797
22 5UFN SAH 2.10084
23 3ELW SAM 2.11268
24 3ELW GP3 2.11268
25 3MCT SAH 2.11268
26 5J5Z FAD 2.11268
27 5U8U FAD 2.11268
28 2F5Z FAD 2.11268
29 3HQP FDP 2.11268
30 5MBX SP5 2.11268
31 5MBX FAD 2.11268
32 3MAG SAH 2.11268
33 3C6K SPD 2.11268
34 3C6K MTA 2.11268
35 2OBF SAH 2.11268
36 2OBF F83 2.11268
37 6A20 ADP 2.11268
38 2B9W FAD 2.11268
39 2XVE FAD 2.11268
40 1XHC FAD 2.11268
41 4CNK FAD 2.11268
42 3LCV SAM 2.13523
43 4YMZ 13P 2.39044
44 2EJU SAH 2.46479
45 1BW9 NAD 2.46479
46 4M52 FAD 2.46479
47 3HDY GDU 2.46479
48 3HDY FDA 2.46479
49 5W7M SAH 2.46479
50 4M52 M52 2.46479
51 1QO8 FAD 2.46479
52 2A8X FAD 2.46479
53 2YYY NAP 2.46479
54 2NVK FAD 2.46479
55 3HDY FAD 2.46479
56 4OPC PGT 2.46479
57 4OPC FDA 2.46479
58 1OMO NAD 2.46479
59 3ZG6 APR 2.46479
60 5JJR SAH 2.46479
61 2VHW NAI 2.46479
62 3DAG FEG 2.46479
63 1BXG HCI 2.46479
64 1X7D ORN 2.46479
65 1X7D NAD 2.46479
66 1K0E TRP 2.46479
67 1BXG NAD 2.46479
68 5XLX SAH 2.48227
69 3EVF SAH 2.52708
70 3EVF GTA 2.52708
71 5CUQ NSC 2.62172
72 3P2E SAH 2.66667
73 3GJ0 GDP 2.71493
74 2Y65 ADP 2.73973
75 1L1E SAH 2.8169
76 1V59 NAD 2.8169
77 1SQF SAM 2.8169
78 1V59 FAD 2.8169
79 1H3F TYE 2.8169
80 1Q9I FAD 2.8169
81 1Q9I TEO 2.8169
82 3VYW SAM 2.8169
83 4ZCC FAD 2.8169
84 4ZCC NAI 2.8169
85 3B6R CRN 2.8169
86 1DJN ADP 2.8169
87 5A1S FLC 2.8169
88 1UXG NAD 2.8169
89 1UXG FUM 2.8169
90 5GSN NAP 2.8169
91 5GSN FAD 2.8169
92 2Q7V FAD 2.8169
93 2NPX FAD 2.8169
94 2NPX NAD 2.8169
95 3LXD FAD 2.8169
96 5GSN MMZ 2.8169
97 6F97 FAD 2.8169
98 1H2B NAJ 2.8169
99 3O9Z NAD 2.8169
100 3O9Z AKG 2.8169
101 4UP4 GAL NAG 2.8169
102 4D5G TPP 2.8169
103 4D5G FAD 2.8169
104 2R4J FAD 2.8169
105 2R4J 13P 2.8169
106 2DT5 NAD 2.8436
107 2WA2 SAM 2.89855
108 5L4R CPT 2.89855
109 1MVQ MMA 2.9661
110 5N5D SAM 3.09735
111 6DUB SAH 3.15315
112 1PJS NAD 3.16901
113 2CDU ADP 3.16901
114 4A6D SAM 3.16901
115 6AA8 NAD 3.16901
116 3L9W AMP 3.16901
117 3L9W GSH 3.16901
118 5CIC 51R 3.16901
119 1H82 FAD 3.16901
120 1H82 GZZ 3.16901
121 1SC6 NAD 3.16901
122 5Y8L NAD 3.16901
123 5Y8L HUI 3.16901
124 4RPL FAD 3.16901
125 4RPL 3UC 3.16901
126 2CDU FAD 3.16901
127 3U31 NAD 3.16901
128 2GV8 FAD 3.16901
129 2GVC FAD 3.16901
130 1MUU NAD 3.16901
131 1VKO NAD 3.16901
132 4YJK URA 3.1746
133 1VC9 ATP 3.1746
134 1VBO MAN 3.3557
135 1VBO MAN MAN MAN 3.3557
136 1ZGA SAH 3.36134
137 2AG8 NAP 3.42205
138 3RKR NAP 3.43511
139 3NZ1 3NY 3.44828
140 4POO SAM 3.5
141 4AZW SAM 3.52113
142 1U2Z SAH 3.52113
143 5YF1 8V0 3.52113
144 5J60 FAD 3.52113
145 4YAC NAI 3.52113
146 1DLJ NAI 3.52113
147 3OA2 NAD 3.52113
148 1MV8 NAD 3.52113
149 1FP1 SAH 3.52113
150 1RZM E4P 3.52113
151 3KLJ FAD 3.52113
152 4JNA FAD 3.52113
153 5N6C NAD 3.52113
154 5YF1 SFG 3.52113
155 1U1I NAD 3.52113
156 5YRG BGC GLC 3.52113
157 3VPH NAD 3.52113
158 3K7M FAD 3.52113
159 4TM3 FAD 3.52113
160 2XVF FAD 3.52113
161 3VPH OXM 3.52113
162 4BV6 FAD 3.52113
163 1HYH NAD 3.52113
164 1DLJ UGA 3.52113
165 2CYC TYR 3.52113
166 5OC1 FAD 3.52113
167 4E13 NAD 3.53357
168 1XTP SAI 3.54331
169 4KXQ APR 3.55872
170 2BRY FAD 3.62173
171 3WV8 ATP 3.66972
172 2VT3 ATP 3.72093
173 2FMD MAN MAN 3.75
174 3BGD PM6 3.84615
175 3BGD SAH 3.84615
176 1Q0S SAH 3.861
177 5THZ SAH 3.87324
178 1FP2 SAH 3.87324
179 5T67 JHZ 3.87324
180 5T67 SAH 3.87324
181 3B1F NAD 3.87324
182 1VJT NAD 3.87324
183 5THY SAH 3.87324
184 5YJI SAH 3.87324
185 5YJI 8WO 3.87324
186 4GUS FAD 3.87324
187 4FWE FAD 3.87324
188 1RP0 AHZ 3.87324
189 4GUT FAD 3.87324
190 4HSU FAD 3.87324
191 4LIK CIT 3.87324
192 1V6A TRE 3.87324
193 5JGL SAM 3.87324
194 1V8K ANP 3.87324
195 2NU8 COA 3.87324
196 2RGO FAD 3.87324
197 3JQ9 AX1 3.87324
198 1YBH FAD 3.87324
199 6CEP NAD 3.87324
200 4WCX ALA 3.87324
201 3BP1 GUN 3.87324
202 2O7B HC4 3.87324
203 1RM0 NAI 3.87324
204 4E5N NAD 3.87324
205 5NMX NAP 3.87324
206 1I9G SAM 3.92857
207 2F1K NAP 3.94265
208 1VE3 SAM 3.96476
209 3FPZ AHZ 3.98773
210 2HK9 ATR 4
211 4QM7 GTP 4.09357
212 5BW4 SAM 4.11985
213 5I39 FAD 4.16667
214 4BLW AMP 4.22535
215 4BLW SAH 4.22535
216 4M3P HCS 4.22535
217 4PLG NAI 4.22535
218 4PLG OXM 4.22535
219 1REO FAD 4.22535
220 5W7R SAH 4.22535
221 2JHP SAH 4.22535
222 5ZYN FAD 4.22535
223 3QPB URA 4.22535
224 1GTE FAD 4.22535
225 3COB ADP 4.22535
226 6GAR FAD 4.22535
227 5YAP NAI 4.22535
228 2YVE MBT 4.22535
229 5TOW NAI 4.22535
230 5TOW ADN 4.22535
231 3F8D FAD 4.22535
232 3A4M ADP 4.23077
233 2HJR APR 4.26829
234 1I1N SAH 4.42478
235 1TE2 PGA 4.42478
236 1JQ3 AAT 4.57746
237 4RVG TYD 4.57746
238 6ECU SAH 4.57746