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Receptor
PDB id Resolution Class Description Source Keywords
1S9D 1.8 Å NON-ENZYME: TRANSPORT ARF1[DELTA 1-17]-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SE BOS TAURUS PROTEIN TRANSPORT/EXCHANGE FACTOR PROTEIN TRANSPORT-EXCHANGCOMPLEX
Ref.: STRUCTURAL SNAPSHOTS OF THE MECHANISM AND INHIBITIO GUANINE NUCLEOTIDE EXCHANGE FACTOR NATURE V. 426 525 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AFB A:403;
Valid;
none;
submit data
280.359 C16 H24 O4 C[C@H...
GDP A:401;
Valid;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:402;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1S9D 1.8 Å NON-ENZYME: TRANSPORT ARF1[DELTA 1-17]-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SE BOS TAURUS PROTEIN TRANSPORT/EXCHANGE FACTOR PROTEIN TRANSPORT-EXCHANGCOMPLEX
Ref.: STRUCTURAL SNAPSHOTS OF THE MECHANISM AND INHIBITIO GUANINE NUCLEOTIDE EXCHANGE FACTOR NATURE V. 426 525 2003
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1R8S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1S9D - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1R8Q - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 175 families.
1 1R8S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1S9D - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1R8Q - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 149 families.
1 1R8S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1S9D - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1R8Q - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
4 2R09 - 4IP C6 H16 O18 P4 [C@H]1([C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AFB; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 AFB 1 1
Ligand no: 2; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1S9D; Ligand: GDP; Similar sites found with APoc: 670
This union binding pocket(no: 1) in the query (biounit: 1s9d.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 1DAK DPU 1.82927
2 1DAK ADP 1.82927
3 3B7G ANP 2.43902
4 4KVX ACO 2.5641
5 1KO8 6PG 2.85714
6 4WZ6 ATP 2.95567
7 2RGX AP5 2.95567
8 2W58 ADP 2.9703
9 3ITJ CIT 3.04878
10 3ITJ FAD 3.04878
11 3IUY AMP 3.04878
12 1S7N COA 3.04878
13 4AVB ACO 3.04878
14 5H4S RAM 3.04878
15 2ZW5 COA 3.04878
16 3BOS CDP 3.44828
17 2IS6 ADP 3.44828
18 4XGU ADP 3.44828
19 4GBM A3P 3.44828
20 1CR1 TTP 3.44828
21 1X8J A3P 3.44828
22 3BFX A3P 3.44828
23 2PZE ATP 3.65854
24 3UIE ANP 3.65854
25 2DPY ADP 3.65854
26 5Y6N ADP 3.65854
27 5VGR GDP 3.65854
28 1NST A3P 3.65854
29 5KSP GDP 3.68421
30 1DAR GDP 3.94089
31 1V8K ANP 3.94089
32 1Q20 PLO 3.94089
33 1Q20 A3P 3.94089
34 5XKT GNP 4
35 5E5U MLI 4.0201
36 3BFV ADP 4.05904
37 1BO4 COA 4.16667
38 3H86 AP5 4.26829
39 5G3Y ADP 4.26829
40 1KUV CA5 4.26829
41 4KOT CE3 4.32099
42 4D81 ADP 4.4335
43 1T8U A3P 4.4335
44 1T8U UAP SGN IDS SGN 4.4335
45 5KF9 ACO 4.4335
46 4OOE FOM 4.4335
47 4OOE NDP 4.4335
48 3VPB ADP 4.4335
49 4H6U ACO 4.5
50 4LJ9 ACP 4.71976
51 5W7Q GDP 4.87805
52 3LRE ADP 4.87805
53 3E70 GDP 4.87805
54 1IWE IMP 4.87805
55 1JJV ATP 4.87805
56 4IEE AGS 4.87805
57 3ZFD ANP 4.87805
58 5ZB0 ADP 4.87805
59 5ZB0 TYD 4.87805
60 5LLB 6YZ 4.87805
61 4EHU ANP 4.87805
62 4LPS GDP 4.92611
63 2GKS ADP 4.92611
64 4BFW ZVW 4.92611
65 2FAH GDP 4.92611
66 3ZQ6 ADP ALF 4.92611
67 1RJW ETF 4.92611
68 1UJ2 C5P 4.92611
69 1UJ2 ADP 4.92611
70 4FCW ADP 5.14469
71 4AKB GAL 5.26316
72 1WS5 MMA 5.26316
73 1WS4 AMG 5.26316
74 1UGY GLA BGC 5.26316
75 1WS4 GYP 5.26316
76 1KUJ MMA 5.26316
77 1UGW GAL 5.26316
78 5W76 GDP 5.41872
79 3EWA ANP 5.41872
80 4TL6 ANP 5.41872
81 1YTM ATP 5.41872
82 2B8T THM 5.41872
83 2C9O ADP 5.41872
84 2ZPT A3P 5.41872
85 5YT0 GDP 5.4878
86 2Y65 ADP 5.4878
87 3IIJ ADP 5.4878
88 4CS9 AMP 5.4878
89 5XDR ADP 5.4878
90 2ZTS ADP 5.4878
91 5MEX SZZ 5.4878
92 1W5T ADP 5.4878
93 5MEX PAP 5.4878
94 1W5T ANP 5.4878
95 3SXN COA 5.4878
96 1Q19 APC 5.4878
97 3KTA AP5 5.78035
98 1XKV ATP 5.91133
99 3EZ2 ADP 5.91133
100 4PX9 ADP 5.91133
101 4IOK ADP 5.91133
102 3TBK ANP 5.91133
103 5K5Z ANP 5.91133
104 4IOK XPO 5.91133
105 2I4I AMP 5.91133
106 1SKQ GDP 6.09756
107 1GOJ ADP 6.09756
108 1QF5 RPL 6.09756
109 1QF5 GDP 6.09756
110 3DC4 ADP 6.09756
111 1G3Q ADP 6.09756
112 1ZUI SKM 6.09756
113 3QXC ATP 6.09756
114 1XX6 ADP 6.09756
115 3KJI ADP 6.09756
116 4HSE ADP 6.09756
117 1Z83 AP5 6.09756
118 3DKP ADP 6.09756
119 4A4Z ANP 6.09756
120 3MGB PAP 6.09756
121 5NM7 GLY 6.09756
122 2VWT PYR 6.09756
123 6BA2 7KM 6.09756
124 1XEX ATP 6.39535
125 5U32 GDP 6.40394
126 4TTQ ATP 6.40394
127 4GOX A3P 6.40394
128 2GDJ ANP 6.40394
129 1Z6T ADP 6.40394
130 5J1J ANP 6.40394
131 2D7D ADP 6.40394
132 3Q9L ATP 6.40394
133 3FYH ADP 6.40394
134 2QQ0 ANP 6.52174
135 2QQ0 THM 6.52174
136 2QQ0 TMP 6.52174
137 2QQ0 ADP 6.52174
138 2RCN GDP 6.70732
139 4PPF FLC 6.70732
140 2CBZ ATP 6.70732
141 3NHB ADP 6.70732
142 4ZKD GDP 6.70732
143 5UIV ADP 6.70732
144 1AKY AP5 6.70732
145 4MKG AP5 6.70732
146 4MKF AP5 6.70732
147 2ZR9 DTP 6.70732
148 1E2K TMC 6.70732
149 4KVA GTP 6.70732
150 4TMK T5A 6.70732
151 1G41 ADP 6.70732
152 5TIV A3P 6.70732
153 1IN4 ADP 6.70732
154 2JAQ DCP 6.70732
155 5BYK A3P 6.70732
156 5BYK OAQ 6.70732
157 1NY5 ADP 6.70732
158 3FVQ ATP 6.70732
159 1YXM ADE 6.70732
160 5K2M ADP 6.70732
161 1CJW COT 6.70732
162 5ZCT ANP 6.70732
163 4UP4 GAL NAG 6.70732
164 3U6B GDP 6.89655
165 2HCJ GDP 6.89655
166 5JBQ GDP 6.89655
167 1D8T GDP 6.89655
168 4G5G GDP 6.89655
169 3U6K GDP 6.89655
170 2BVN GNP 6.89655
171 1T5C ADP 6.89655
172 2YOH WMJ 6.89655
173 4OHY ANP 6.89655
174 3IO3 ADP 6.89655
175 3QVV 3QV 6.89655
176 3QVV A3P 6.89655
177 4ZDJ UTP 6.89655
178 3MD0 GDP 7.04225
179 2JJK R15 7.10059
180 1MKY GDP 7.31707
181 5W75 GDP 7.31707
182 4RD0 GDP 7.31707
183 1F9V ADP 7.31707
184 2WHX ADP 7.31707
185 4NE2 SH2 7.31707
186 4NE2 ADP 7.31707
187 1SQ5 ADP 7.31707
188 5LB3 ADP 7.31707
189 1R0X ATP 7.31707
190 3T34 GDP 7.31707
191 5W75 SUC 7.31707
192 2JLR ANP 7.31707
193 2WOJ ADP ALF 7.31707
194 1AQU A3P 7.31707
195 4NSQ COA 7.31707
196 1CM0 COA 7.31707
197 2B8W ALF 5GP 7.31707
198 6AIC AMP 7.31707
199 5H7J GCP 7.38916
200 5H7K GDP 7.38916
201 4V03 ADP 7.38916
202 1F5N GNP 7.38916
203 6C90 ADP 7.38916
204 1G3M PCQ 7.38916
205 1G3M A3P 7.38916
206 3BER AMP 7.38916
207 3R96 AMP 7.44681
208 3R96 ACO 7.44681
209 4OI4 ATP 7.82609
210 1P72 ADP 7.88177
211 2QEN ADP 7.88177
212 2OBM ADP 7.88177
213 3BD9 A3P 7.88177
214 1J99 AND 7.88177
215 4J0Q GDP 7.92683
216 5HCN GCP 7.92683
217 1BG2 ADP 7.92683
218 1LVG ADP 7.92683
219 1TQ4 GDP 7.92683
220 5L3V GDP 7.92683
221 4NU0 AP5 7.92683
222 5G41 AP5 7.92683
223 1XMV ADP 7.92683
224 5I34 GDP 7.92683
225 4ZNL BEF ADP 7.92683
226 4RZ3 ADP 7.92683
227 1VKJ A3P 7.92683
228 2XAU ADP 7.92683
229 6B4K ANP 7.92683
230 5MZN ADP 7.92683
231 3OII SAH 7.92683
232 6H5E ANP 7.92683
233 5AHM IMP 7.92683
234 2C77 GNP 8.37438
235 2C78 GNP 8.37438
236 2FSH ANP 8.37438
237 2IXE ATP 8.37438
238 2O0J ADP 8.37438
239 3QKT ANP 8.37438
240 4U5X GNP 8.42697
241 5H68 AGS 8.52941
242 5FG3 GDP 8.53659
243 3B9Q MLI 8.53659
244 2OG2 MLI 8.53659
245 4BQS K2Q 8.53659
246 4BQS ADP 8.53659
247 1WDT GTP 8.53659
248 3TMK T5A 8.53659
249 4YDS ATP 8.53659
250 5Z69 AGS 8.53659
251 5GVR LMR 8.53659
252 5L3R GCP 8.53659
253 4PJ3 ANP 8.53659
254 4XVU ATP 8.53659
255 4R2I ANP 8.53659
256 2QG6 NMN 8.54271
257 1QF9 ALF 8.76289
258 1QF9 ADP 8.76289
259 1QF9 C5P 8.76289
260 4KFU ACP 8.86699
261 3DZD ADP 8.86699
262 4YS0 ADP 8.86699
263 4LIK CIT 8.86699
264 5KUT GDP 8.99471
265 2VBQ BSJ 9.09091
266 2AWN ADP 9.14634
267 4PC3 GDP 9.14634
268 2VVG ADP 9.14634
269 1M7G AV2 9.14634
270 4H1V GNP 9.14634
271 5KSZ GCP 9.14634
272 1WF3 GNP 9.14634
273 5WC2 ADP 9.14634
274 4LYA ATP 9.14634
275 5IRN ADP 9.14634
276 2VB6 ADP BEF 9.14634
277 4PFO ADP 9.14634
278 1M7G ADP 9.14634
279 1M7G ADX 9.14634
280 1QSN COA 9.25926
281 1S3G AP5 9.35961
282 4IDN GNP 9.35961
283 1NJF ADP 9.35961
284 1NJF AGS 9.35961
285 1QHG ATP 9.35961
286 4ZG4 VO4 ADP 9.35961
287 1VM6 NAD 9.35961
288 1KK1 GNP 9.7561
289 3CNL GNP 9.7561
290 5CK5 GDP 9.7561
291 3HU3 AGS 9.7561
292 2Q2Y ADP 9.7561
293 2Q2Y MKR 9.7561
294 5IFS ADP 9.7561
295 1W4R TTP 9.7561
296 2ORV 4TA 9.7561
297 2Z5F A3P 9.7561
298 4QRH 0O2 9.7561
299 5K04 COA 9.7561
300 2BEK ATP 9.7561
301 4UXH T5A 9.78261
302 4DKX GDP 9.85222
303 6DEF GCP 9.85222
304 3FKQ ATP 9.85222
305 2D2F ADP 9.85222
306 4A62 ANP 9.85222
307 2KIN ADP 10
308 1H65 GDP 10
309 1G7S GDP 10.3448
310 4LC1 GDP 10.3448
311 5LTJ ADP 10.3448
312 1FP6 ADP 10.3448
313 3VX3 ADP 10.3448
314 5LTJ BEF 10.3448
315 1PUJ GNP 10.3659
316 6G14 G4P 10.3659
317 2XT3 ADP 10.3659
318 4Q1A UDP 10.3659
319 4Q1A 2XZ 10.3659
320 1XP8 AGS 10.3659
321 4YJ1 ADP 10.3659
322 5BQ5 ADP BEF 10.3659
323 1IHU AF3 10.3659
324 1IHU ADP 10.3659
325 3RC3 ANP 10.3659
326 4B16 NAG 10.3659
327 4Y4V DAL 10.3659
328 2B4D COA 10.5263
329 2B4B COA 10.5263
330 1SVI GDP 10.7692
331 1YRB GDP 10.8374
332 5ZXD ATP 10.8374
333 1ZRH A3P 10.8374
334 1B7T ADP 10.8974
335 2JEV NHQ 10.9195
336 1RRC ADP 10.9756
337 5YV5 ADP 10.9756
338 3FB4 AP5 10.9756
339 3WXM GTP 10.9756
340 5L3W GDP 10.9756
341 4X8O AP5 10.9756
342 1OS1 ATP 10.9756
343 1OS1 PYR 10.9756
344 5VHC BEF ADP 10.9756
345 5L3S GNP 10.9756
346 1VHT BA3 10.9756
347 1NHX PEP 10.9756
348 1NHX FTB 10.9756
349 2GMV UN8 10.9756
350 2GMV PEP 10.9756
351 3X44 PUS 10.9756
352 4HUT ATP 10.9756
353 5J1S ATP 10.9756
354 1KK8 BEF ADP 11.039
355 1HTW ADP 11.3924
356 1F2U ATP 11.4094
357 4P3Y GDP 11.5385
358 2CDN ADP 11.5854
359 2PL3 ADP 11.5854
360 3WYA GDP 11.8227
361 3WY9 GDP 11.8227
362 5GOE GDP 11.8227
363 1ZIN AP5 11.8227
364 3RNM FAD 12.069
365 1GXU 2HP 12.0879
366 6A20 ADP 12.1951
367 5TSH ANP 12.1951
368 5TSH ADP 12.1951
369 1ION ADP 12.1951
370 3FWY ADP 12.1951
371 1W0J ADP 12.1951
372 5ZBR ANP 12.1951
373 5EXT ADP 12.1951
374 1W0J ADP BEF 12.1951
375 5H67 ATP 12.1951
376 1ME8 RVP 12.1951
377 1QHH ATP 12.1951
378 1NN5 ANP 12.1951
379 1NN5 2DT 12.1951
380 2F3R G5P 12.3153
381 2IL4 COA 12.6214
382 4ITM ATP 12.6984
383 2GJ8 ALF GDP 12.7907
384 3TK1 GDP 12.8049
385 4P4T GDP 12.8049
386 3V2U ATP 12.8049
387 1SVM ATP 12.8079
388 2OZE AGS 12.8079
389 1ZEI CRS 13.2075
390 4B47 GDP 13.2231
391 1D2E GDP 13.3005
392 4JLV ADP 13.4146
393 1U0J ADP 13.4146
394 1OE0 TTP 13.4146
395 5HV7 RBL 13.4146
396 2HT6 GDP 13.7931
397 2HF9 GSP 13.7931
398 1G6O ADP 13.7931
399 3ZLR X0B 13.9241
400 4IHQ ADP 14.0244
401 4WOP CTP 14.0244
402 2CHG ANP 14.0244
403 5I0H ADP BEF 14.0244
404 2PEZ GGZ 14.0244
405 2PEZ DAT 14.0244
406 4CVN ADP 14.5985
407 1G7C 5GP 14.6341
408 2OFW ADX 14.6341
409 1X6V ADP 14.6341
410 4AG5 ADP 14.6341
411 1LVK MNT BEF 14.6341
412 1OYY AGS 14.6341
413 6FAA ADP 14.6341
414 3P4X ADP 14.7783
415 3WQT ANP 14.7783
416 4WZA ACP 15.2439
417 4WZA ADP 15.2439
418 5N69 ADP 15.2439
419 5HGZ ACO 15.2439
420 5HH0 COA 15.2439
421 1UKZ ADP 15.2709
422 5WRJ A3P 15.2709
423 5WRI A3P 15.2709
424 4KBF AMP 15.2709
425 3A4M ADP 15.7635
426 3ZS9 ADP ALF 15.7895
427 5M04 GDP 15.8537
428 2ZPA ADP 15.8537
429 2GK6 ADP 15.8537
430 2V7Q ATP 16
431 2CK3 ANP 16
432 2CK3 ADP 16
433 2V7Q ADP 16
434 1OFH ADP 16.092
435 3F8K COA 16.25
436 1Y63 ADP 16.3043
437 4TMZ GSP 16.4634
438 4NCN GTP 16.4634
439 3QF7 ANP 16.4634
440 3RLF ANP 16.4634
441 4AF0 IMP 16.4634
442 3Q72 GNP 16.8675
443 2NCD ADP 17.0732
444 4E03 ADP 17.0732
445 2ZE7 AMP 17.0732
446 2ZE7 DST 17.0732
447 2GWH A3P 17.2414
448 6B8B ADP 17.2691
449 2IYL GDP 17.6829
450 1RJ9 GCP 17.6829
451 5MVR ADP 17.9012
452 1R6B ADP 18.2266
453 2CJW GDP 18.2927
454 3AB3 GDP 18.2927
455 1ZCB GDP 18.2927
456 3CX8 GSP 18.2927
457 1P9B GDP 18.2927
458 1W7J ADP BEF 18.543
459 1M7B GTP 18.9024
460 1GWN GTP 18.9024
461 5FHD ADP ALF 18.9024
462 4QOS ADP 18.9024
463 5FTB ANP 18.9024
464 2J5V PCA 18.9024
465 4XTR ADP 18.9189
466 4XTR ATP 18.9189
467 2QZ4 ADP 19.2118
468 2WKQ GTP 19.5122
469 1E96 GTP 19.5122
470 5LEF GTP 19.697
471 1XPJ TLA 19.8413
472 1I4D GDP 20.122
473 1DS6 GDP 20.122
474 2FJU GSP 20.122
475 1RYH GNP 20.122
476 2W2X GSP 20.122
477 1HE1 GDP 20.122
478 3SBD GNP 20.122
479 4HI0 GDP 20.6897
480 3Q85 GNP 20.7317
481 2J0V GDP 20.7317
482 3H4S ADP 20.7317
483 3DEF GDP 20.7317
484 4FRZ ADP 20.7317
485 2CE7 ADP 20.7317
486 2ZEJ GDP 21.3415
487 6CS8 F9Y 21.3415
488 5BN3 ADP 21.3415
489 3ZIA ATP 21.6749
490 3ZIA ADP 21.6749
491 3EC1 GDP 21.9512
492 5IRR GSP 21.9512
493 1FNN ADP 21.9512
494 3VMF GTP 22.1675
495 6AU6 GDP 22.561
496 2XTZ GSP 22.561
497 1CS4 GSP 22.561
498 1G4U GDP 22.561
499 3GJX GTP 22.561
500 1MH1 GNP 22.561
501 3GJ3 GDP 23.1707
502 4HAT GNP 23.1707
503 5UWQ GNP 23.1707
504 5UWU GNP 23.1707
505 3GJ0 GDP 23.1707
506 5UWO GNP 23.1707
507 3GJ7 GDP 23.1707
508 3CH5 GDP 23.1707
509 3GJ4 GDP 23.1707
510 3GJ8 GDP 23.1707
511 5BXQ GDP 23.1707
512 3GJ5 GDP 23.1707
513 5DIF GNP 23.1707
514 5UWI GNP 23.1707
515 5UWW GNP 23.1707
516 5UWH GNP 23.1707
517 5UWR GNP 23.1707
518 5UWJ GNP 23.1707
519 3M1I GTP 23.1707
520 1IBR GNP 23.1707
521 3WYG GTP 23.1707
522 3WYF GTP 23.1707
523 5UWP GNP 23.1707
524 5UWS GNP 23.1707
525 5DI9 GNP 23.1707
526 4R43 GDP 23.1707
527 2FNA ADP 23.1707
528 2BIF ANP 23.7805
529 2BIF SIN 23.7805
530 3REF GDP 23.7805
531 4ZOH MCN 23.7805
532 6CIT GNP 23.8095
533 5OEC GDP 24.3902
534 2ZJ5 ADP 24.3902
535 1K6M AGS 25.6098
536 5UPK GNP 26.2195
537 1NF3 GNP 26.2195
538 4YC7 GNP 26.8293
539 2NGR GDP 26.8293
540 4DID GDP 26.8293
541 2WMO GTP 26.8293
542 1A4R GNH 26.8293
543 1GRN GDP 26.8293
544 1A4R GDP 26.8293
545 4ITR GDP 26.8293
546 5M7P ADP 26.8293
547 1TAD GDP 28.0488
548 1TAD ALF 28.0488
549 1GOT GDP 28.0488
550 1X1R GDP 28.0899
551 2GCO GNP 28.3582
552 2GCN GDP 28.3582
553 5AK0 8V1 28.6585
554 5UQW GDP 29.1005
555 6CRK GDP 29.2683
556 5KDO GDP 29.2683
557 1Y3A GDP 29.2683
558 1FQJ GDP 29.2683
559 1FQK GDP 29.2683
560 1GP2 GDP 29.2683
561 2ODE ALF GDP 29.2683
562 1BH2 GSP 29.2683
563 5TB5 GDP 29.7297
564 5TAR GDP 29.7297
565 1SVK ALF GDP 29.878
566 5XC5 GTP 29.878
567 4QM7 GTP 29.878
568 4KVG GTP 30.4878
569 5HR5 ADP 31.0976
570 6FA4 GNP 31.2139
571 2C5L GTP 31.2139
572 4K81 GTP 31.5789
573 5DHF GNP 31.5789
574 4HDO GNP 31.7073
575 4D0G GTP 31.7073
576 4HDQ GNP 31.7073
577 3X1Z GNP 31.7073
578 1GUA GNP 32.0988
579 5E95 GDP 32.1429
580 6BSX GDP 32.3171
581 2D7C GTP 32.3171
582 6BSX E7S 32.3171
583 6BVJ GNP 32.3353
584 6D5E GNP 32.3353
585 6BVK GNP 32.3353
586 6D5J GNP 32.3353
587 6BVL GNP 32.3353
588 6D59 GNP 32.3353
589 6BVI GNP 32.3353
590 6D5L GNP 32.3353
591 6D56 GNP 32.3353
592 6D55 GNP 32.3353
593 6D5H GNP 32.3353
594 6BVM GNP 32.3353
595 6D5G GNP 32.3353
596 6D5M GNP 32.3353
597 6D5V GNP 32.3353
598 3KUD GDP 32.5301
599 1WQ1 GDP 32.5301
600 2UZI GTP 32.5301
601 1NVV GNP 32.5301
602 3DDC GNP 32.5301
603 1WQ1 AF3 32.5301
604 5O2T GSP 32.5444
605 3T1O GDP 32.9268
606 3T12 GDP ALF 32.9268
607 2HV8 GTP 32.9268
608 2EW1 GNP 32.9268
609 1CLU DBG 32.9268
610 5WLB GNP 33.1325
611 2QN6 GDP 33.3333
612 2OM2 GDP 33.3333
613 1KAO GDP 33.5329
614 5JCZ GDP 33.5366
615 2F9L GDP 33.5366
616 1ZC3 GNP 33.5366
617 4C4P GNP 33.5366
618 2BME GNP 33.5366
619 4LX0 BEF GDP 33.5366
620 2XTN GTP 33.5366
621 3T5G GDP 34.1463
622 2A9K GDP 34.1463
623 1U8Z GDP 34.1463
624 5Z2M GTP 34.1463
625 3MJH GTP 34.1463
626 1UAD GNP 34.1463
627 5OCG GNP 34.1463
628 3E5H GNP 34.1463
629 2EFE GNH 34.7561
630 1YQT ADP 34.7561
631 2FFQ GSP 34.7561
632 1TU3 GNP 34.7561
633 3CPJ GDP 35.3659
634 4D0N GDP 35.3659
635 6BC0 GSP 35.3659
636 3LXR GDP 35.3659
637 3RWO GDP 35.3659
638 1EK0 GNP 35.3659
639 6BCB GSP 35.3659
640 6BCA GSP 35.3659
641 5WDR GNP 35.3659
642 1CXZ GSP 35.3659
643 2G77 GDP 35.9756
644 1G16 GDP 35.9756
645 1KMQ GNP 36.5854
646 4XOI GTP 36.5854
647 1KY3 GDP 37.1951
648 5HPY GDP 37.1951
649 5JCP GDP ALF 37.1951
650 1OW3 GDP 37.1951
651 5IRC GDP 37.1951
652 4XSH GSP 37.1951
653 1TX4 ALF GDP 37.1951
654 5UWT GNP 39.1304
655 3BC1 GNP 39.6341
656 3QBT GNP 39.6341
657 4LHW GNP 39.6341
658 3TNF GNP 39.6341
659 3RAB GNP 40.2439
660 1D5C GDP 40.7407
661 2Y8E GNP 40.8537
662 5O74 GDP 42.0732
663 3SFV GDP 42.0732
664 5SZH GNP 42.0732
665 3TKL GTP 42.6829
666 3NKV GNP 42.6829
667 3PQC GDP 43.9024
668 1LFD GNP 44.3114
669 2FH5 GTP 44.5122
670 4DCT GDP 45.122
Pocket No.: 2; Query (leader) PDB : 1S9D; Ligand: AFB; Similar sites found with APoc: 137
This union binding pocket(no: 2) in the query (biounit: 1s9d.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5IF4 6AK 1.88679
2 3RV5 DXC 2.24719
3 3DAK ANP 2.43902
4 4H3Q ANP 2.46305
5 4H3P ANP 2.46305
6 4NAT 2W5 3.125
7 4NAT ADP 3.125
8 5GZ9 ANP 3.44828
9 5DEY 59T 3.44828
10 4E93 GUI 3.65854
11 2F2U M77 3.65854
12 5XVG 8FX 3.65854
13 4U44 3D9 3.91566
14 4C0R GDS 3.94089
15 4EUU BX7 4.26829
16 2V58 LZJ 4.26829
17 2R3A SAM 4.26829
18 5N87 N66 4.26829
19 3UIM ANP 4.26829
20 2OFV 242 4.4335
21 4A4X JUP 4.4335
22 2H8H H8H 4.4335
23 4OOE NDP 4.4335
24 5X8I SQZ 4.4335
25 2PVN P63 4.4335
26 1U5R ATP 4.4335
27 4GJ3 0XP 4.87805
28 5USZ SKE 4.87805
29 4KS7 X4Z 4.87805
30 4NZ6 DLY 4.87805
31 5JFS 6K0 4.87805
32 5VCV 1N1 4.92611
33 4UAL 3FV 4.92611
34 4QTB 38Z 5.26316
35 5NKB 8ZT 5.41872
36 6GIN IR2 5.4878
37 2J7T 274 5.4878
38 4P5Z Q7M 5.4878
39 4OTH DRN 5.4878
40 2Y6O 1N1 5.4878
41 5CSD ACD 5.66038
42 4OH4 ANP 5.91133
43 5LPZ ADP 5.91133
44 3LXK MI1 5.91133
45 5LPB ADP 5.91133
46 5U6C 7YS 5.91133
47 1VJY 460 6.09756
48 4QMN DB8 6.09756
49 6G34 5ID 6.09756
50 4G6I RS3 6.09756
51 3GGF GVD 6.09756
52 6AM8 PLT 6.09756
53 5YIC 8VO 6.09756
54 3ALN ANP 6.09756
55 4OUC 5ID 6.09756
56 3DGY 2GP 6.18557
57 3COW 52H 6.40394
58 5EEH P9P 6.70732
59 2VPQ ANP 6.70732
60 5WNL STU 6.70732
61 6CMJ F6J 6.70732
62 1V0O INR 6.89655
63 6FCH PRP 7.30337
64 5AX9 4KT 7.31707
65 3WVR AMP 7.31707
66 1XVB BHL 7.31707
67 2B9H ADP 7.38916
68 2B9F ADP 7.38916
69 2B9J ADP 7.38916
70 5HVJ ANP 7.38916
71 5O2D 9HH 7.5
72 3ND6 ATP 7.60234
73 5YW5 ADE 7.82123
74 4CSV STI 7.92683
75 4YMJ 4EJ 7.92683
76 3V8S 0HD 7.92683
77 5NNT DPV 8.10811
78 4XV1 904 8.37438
79 4CQE CQE 8.37438
80 4M69 ANP 8.37438
81 4I94 ANP 8.53659
82 5TZO 7V7 9.04255
83 6CZ3 FLJ 9.14634
84 4PYW ACE THR THR ALA ILE NH2 9.14634
85 5H2U 1N1 9.14634
86 5IUY BOG 9.35961
87 5WO4 B7V 9.35961
88 6C7Y ADP 9.35961
89 3O0G 3O0 9.35961
90 3CHT 4NB 9.7561
91 1RE8 BD2 9.7561
92 2GU8 796 9.7561
93 5FBN 5WF 9.7561
94 4FC7 NAP 9.7561
95 4FC7 COA 9.7561
96 2D3M COA 9.7561
97 4NG2 OHN 9.78261
98 4AUA 4AU 9.85222
99 3GNI ATP 9.85222
100 3H9R TAK 10.0917
101 5HES 032 10.3659
102 3G5D 1N1 10.3659
103 5L0S UDP 10.3659
104 4O4K 2PK 10.3659
105 2WU6 DKI 10.3659
106 5VC5 96M 10.8374
107 4CRL C1I 10.9756
108 5LWY OLB 11.215
109 6G9I CXX 11.3095
110 4CJX 9L9 12.3153
111 4Y8D 49J 12.8049
112 3WQQ NDP 12.8049
113 3WQQ IB3 12.8049
114 4CFU 2WC 12.8079
115 5T8O 76Z 12.8079
116 4IDT T28 13.3005
117 2XMY CDK 14.2857
118 6GUE FB8 14.2857
119 4MV1 ADP 14.6341
120 5Y86 HRM 14.6341
121 3VRY B43 15.2439
122 2HK5 1BM 15.2439
123 3SLS ANP 15.7635
124 6BXI ANP 15.7635
125 4NFE BEN 15.8537
126 1LOX RS7 15.8537
127 6GU6 1QK 16.6667
128 5HQ0 LZ9 16.6667
129 3WCA FPS 16.7488
130 5B0W 22B 17.6829
131 5QIN J2V 18.2266
132 6F3G CJN 18.2927
133 5UIU 8CG 18.2927
134 2Z49 AMG 23.1707
135 4ZOH MCN 23.7805
136 1UUY PPI 24.3902
137 4OUJ LBT 26.1084
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