Receptor
PDB id Resolution Class Description Source Keywords
1RJY 1.9 Å NON-ENZYME: IMMUNE MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND HERPES SIMPLEX VIRUS G LYCOPROTEIN B PEPTIDE MUS MUSCULUS MHC CLASS I PEPTIDE VIRUS TCR HERPES IMMUNE SYSTEM
Ref.: STRUCTURAL BASIS FOR THE RESTORATION OF TCR RECOGNITION OF AN MHC ALLELIC VARIANT BY PEPTIDE SECONDARY ANCHOR SUBSTITUTION J.EXP.MED. V. 200 1445 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SER SER ILE GLU PHE ALA ARG LEU P:1;
Q:1;
Valid;
Valid;
none;
none;
submit data
922.051 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1LEK 2.15 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF H-2KBM3 BOUND TO DEV8 MUS MUSCULUS MHC CLASS I ALLOGENEIC COMPLEX WITH PEPTIDE IMMUNE SYSTEM
Ref.: STRUCTURAL COMPARISON OF ALLOGENEIC AND SYNGENEIC T RECEPTOR-PEPTIDE-MAJOR HISTOCOMPATIBILITY COMPLEX C A BURIED ALLOREACTIVE MUTATION SUBTLY ALTERS PEPTID PRESENTATION SUBSTANTIALLY INCREASING V(BETA) INTER J.EXP.MED. V. 195 1175
Members (35)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 199 families.
1 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
2 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
3 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
4 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
5 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
6 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
7 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
8 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
9 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
10 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
11 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
12 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
13 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
14 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
15 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
16 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
17 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
18 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
19 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
20 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
21 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
22 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
23 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
24 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
25 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
26 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
27 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
28 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
29 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
30 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
31 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
32 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
33 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
34 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
35 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
70% Homology Family (343)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
18 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
19 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
20 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
21 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
22 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
23 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
24 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
25 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
26 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
27 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
28 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
29 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
30 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
31 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
32 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
33 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
34 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
35 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
36 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
37 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
38 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
39 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
40 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
41 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
42 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
43 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
44 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
45 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
46 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
47 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
48 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
49 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
50 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
51 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
52 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
53 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
54 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
55 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
56 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
57 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
58 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
59 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
60 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
61 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
62 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
63 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
64 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
66 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
67 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
68 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
69 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
70 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
71 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
72 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
73 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
74 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
75 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
76 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
77 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
78 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
79 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
80 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
81 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
82 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
83 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
84 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
85 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
86 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
87 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
88 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
89 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
90 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
91 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
92 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
93 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
94 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
95 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
96 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
97 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
98 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
100 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
101 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
102 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
103 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
104 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
105 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
106 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
107 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
108 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
109 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
110 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
111 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
112 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
113 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
114 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
115 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
116 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
117 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
118 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
119 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
120 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
121 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
122 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
123 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
124 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
125 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
126 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
127 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
128 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
129 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
130 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
131 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
132 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
133 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
134 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
135 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
136 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
137 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
138 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
139 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
140 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
141 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
142 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
143 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
144 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
145 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
146 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
147 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
148 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
149 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
150 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
151 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
152 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
153 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
154 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
155 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
156 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
157 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
158 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
159 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
160 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
161 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
162 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
163 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
164 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
165 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
166 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
167 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
168 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
169 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
170 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
171 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
172 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
173 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
174 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
175 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
176 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
177 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
178 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
179 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
180 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
181 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
182 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
183 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
184 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
185 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
186 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
187 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
188 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
189 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
190 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
191 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
192 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
193 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
194 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
195 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
196 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
197 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
198 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
199 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
200 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
201 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
202 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
203 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
204 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
205 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
206 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
207 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
208 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
209 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
210 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
211 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
212 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
213 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
214 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
215 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
216 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
217 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
218 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
219 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
220 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
221 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
222 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
223 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
224 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
225 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
226 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
227 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
228 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
229 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
230 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
231 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
232 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
233 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
234 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
235 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
236 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
237 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
238 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
239 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
240 1HSB - ALA VAL ALA n/a n/a
241 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
242 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
243 5GRG - SER SER CYS SER SER CYS n/a n/a
244 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
245 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
246 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
247 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
248 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
249 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
250 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
251 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
252 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
253 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
254 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
255 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
256 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
257 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
258 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
259 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
260 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
261 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
262 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
263 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
264 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
265 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
266 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
267 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
268 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
269 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
270 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
271 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
272 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
273 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
274 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
275 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
276 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
277 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
278 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
279 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
280 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
281 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
282 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
283 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
284 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
285 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
286 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
287 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
288 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
289 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
290 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
291 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
292 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
293 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
294 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
295 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
296 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
297 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
298 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
299 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
300 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
301 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
302 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
303 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
304 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
305 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
306 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
307 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
308 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
309 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
310 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
311 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
312 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
313 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
314 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
315 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
316 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
317 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
318 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
319 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
320 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
321 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
322 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
323 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
324 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
325 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
326 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
327 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
328 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
329 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
330 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
331 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
332 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
333 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
334 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
335 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
336 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
337 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
338 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
339 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
340 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
341 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
342 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
343 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
50% Homology Family (348)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 43 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
18 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
19 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
20 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
21 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
22 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
23 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
24 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
25 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
26 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
27 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
28 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
29 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
30 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
31 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
32 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
33 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
34 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
35 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
36 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
37 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
38 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
39 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
40 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
41 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
42 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
43 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
44 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
45 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
46 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
47 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
48 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
49 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
50 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
51 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
52 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
53 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
54 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
55 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
56 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
57 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
58 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
59 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
60 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
61 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
62 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
63 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
64 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
66 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
67 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
68 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
69 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
70 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
71 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
72 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
73 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
74 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
75 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
76 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
77 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
78 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
79 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
80 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
81 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
82 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
83 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
84 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
85 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
86 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
87 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
88 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
89 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
90 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
91 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
92 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
93 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
94 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
95 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
96 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
97 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
98 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
100 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
101 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
102 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
103 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
104 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
105 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
106 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
107 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
108 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
109 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
110 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
111 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
112 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
113 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
114 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
115 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
116 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
117 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
118 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
119 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
120 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
121 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
122 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
123 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
124 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
125 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
126 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
127 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
128 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
129 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
130 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
131 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
132 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
133 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
134 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
135 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
136 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
137 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
138 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
139 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
140 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
141 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
142 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
143 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
144 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
145 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
146 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
147 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
148 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
149 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
150 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
151 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
152 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
153 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
154 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
155 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
156 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
157 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
158 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
159 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
160 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
161 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
162 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
163 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
164 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
165 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
166 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
167 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
168 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
169 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
170 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
171 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
172 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
173 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
174 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
175 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
176 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
177 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
178 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
179 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
180 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
181 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
182 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
183 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
184 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
185 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
186 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
187 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
188 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
189 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
190 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
191 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
192 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
193 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
194 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
195 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
196 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
197 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
198 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
199 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
200 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
201 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
202 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
203 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
204 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
205 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
206 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
207 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
208 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
209 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
210 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
211 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
212 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
213 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
214 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
215 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
216 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
217 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
218 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
219 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
220 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
221 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
222 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
223 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
224 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
225 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
226 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
227 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
228 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
229 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
230 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
231 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
232 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
233 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
234 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
235 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
236 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
237 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
238 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
239 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
240 1HSB - ALA VAL ALA n/a n/a
241 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
242 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
243 5GRG - SER SER CYS SER SER CYS n/a n/a
244 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
245 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
246 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
247 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
248 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
249 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
250 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
251 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
252 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
253 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
254 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
255 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
256 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
257 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
258 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
259 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
260 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
261 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
262 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
263 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
264 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
265 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
266 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
267 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
268 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
269 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
270 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
271 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
272 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
273 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
274 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
275 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
276 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
277 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
278 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
279 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
280 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
281 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
282 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
283 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
284 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
285 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
286 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
287 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
288 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
289 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
290 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
291 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
292 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
293 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
294 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
295 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
296 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
297 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
298 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
299 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
300 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
301 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
302 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
303 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
304 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
305 4G43 - ILE ASP TRP PHE GLU GLY LYS GLU n/a n/a
306 4E0R - ILE ASP TRP PHE ASP GLY LYS GLU n/a n/a
307 4G42 - ILE ASP TRP PHE ASP GLY LYS ASP n/a n/a
308 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
309 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
310 4CVZ - TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU n/a n/a
311 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
312 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
313 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
314 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
315 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
316 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
317 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
318 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
319 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
320 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
321 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
322 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
323 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
324 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
325 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
326 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
327 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
328 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
329 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
330 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
331 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
332 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
333 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
334 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
335 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
336 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
337 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
338 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
339 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
340 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
341 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
342 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
343 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
344 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
345 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
346 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
347 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
348 1TMC - GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SER SER ILE GLU PHE ALA ARG LEU; Similar ligands found: 193
No: Ligand ECFP6 Tc MDL keys Tc
1 SER SER ILE GLU PHE ALA ARG LEU 1 1
2 SER GLU ILE GLU PHE ALA ARG LEU 0.934579 0.981818
3 PHE ARG SER LYS GLY GLU GLU LEU PHE THR 0.622222 0.915254
4 SER ILE ILE ASN PHE GLU LYS LEU 0.616 0.859649
5 GLU ASP GLU ASP PHE GLU ILE LEU SER LEU 0.614173 0.839286
6 SER GLU LEU GLU ILE LYS ARG TYR 0.612403 0.885246
7 SER SER LEU GLU ASN PHE ARG ALA TYR VAL 0.598592 0.870968
8 GLU GLU PHE GLY ARG ALA PHE SER PHE 0.587786 0.862069
9 GLY ARG PHE ALA ALA ALA ILE ALA LYS 0.584 0.827586
10 ARG ARG ILE TYR ASP LEU ILE GLU LEU 0.58209 0.866667
11 SER ILE ILE GLY PHE GLU LYS LEU 0.581395 0.824561
12 ALA ARG THR GLU LEU TYR ARG SER LEU 0.580153 0.9
13 ALA GLN PHE SER ALA SER ALA SER ARG 0.570248 0.945455
14 GLU ASP GLU ASP PHE GLU ILE LEU SEP LEU 0.560284 0.725806
15 ARG ABA PHE ILE PHE ALA ASN ILE 0.55814 0.862069
16 LEU PRO PHE GLU ARG ALA THR ILE MET 0.554839 0.726027
17 SER SER LEU GLU ASN PHE ALA ALA TYR VAL 0.554745 0.741935
18 GLU ILE ILE ASN PHE GLU LYS LEU 0.553846 0.758621
19 ARG ARG LEU ILE PHE NH2 0.54918 0.854545
20 GLU ALA GLN THR ARG LEU 0.54918 0.875
21 GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE 0.547445 0.864407
22 ILE GLN GLN SER ILE GLU ARG ILE 0.544715 0.892857
23 TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 0.543478 0.809524
24 SER ARG TYR TRP ALA ILE ARG THR ARG 0.540541 0.779412
25 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.537931 0.794118
26 ARG ABA VAL ILE PHE ALA ASN ILE 0.533835 0.910714
27 ASP ALA GLU PHE ARG HIS ASP SER 0.529412 0.71875
28 GLU ARG GLU SEP GLU PHE ASP ILE GLU ASP 0.527778 0.825397
29 GLY ILE LEU GLU PHE VAL PHE THR LEU 0.526718 0.758621
30 ARG VAL LEU PHE GLU ALA MET 0.525547 0.786885
31 SER LEU PHE ASN THR ILE ALA VAL LEU 0.514925 0.807018
32 ILE LEU ALA LYS PHE LEU HIS GLU LEU 0.514286 0.646154
33 PHE LEU ARG GLY ARG ALA TYR VAL LEU 0.513889 0.806452
34 LEU GLU LYS ALA ARG GLY SER THR TYR 0.513514 0.870968
35 GLU THR VAL ARG PHE GLN SER ASP 0.510638 0.946429
36 THR ASN GLU PHE ALA PHE 0.508475 0.62069
37 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.506579 0.753623
38 ASP GLU LEU GLU ILE LYS ALA TYR 0.5 0.704918
39 SER ASP TYR GLN ARG LEU 0.5 0.847458
40 ARG ILE PHE SER 0.5 0.890909
41 SER ARG ILE ARG ILE ARG GLY TYR VAL ARG 0.5 0.901639
42 ILE ARG LYS ILE LEU PHE LEU ASP GLY ILE 0.5 0.847458
43 LEU PRO PHE GLU ARG ALA THR VAL MET 0.496855 0.712329
44 GLU LEU LYS ARG LYS MET ILE TYR MET 0.496504 0.769231
45 PHE TYR ARG ALA LEU MET 0.49635 0.738462
46 GLY ASN PHE LEU GLN SER ARG 0.496296 0.947368
47 SER LEU ASN TYR ILE ILE LYS VAL LYS GLU 0.493056 0.790323
48 ALA ASN SER ARG TRP GLN THR SER ILE ILE 0.489796 0.84375
49 VAL ASN ASP ILE PHE GLU ALA ILE 0.488889 0.736842
50 VAL ALA PHE ARG SER 0.488 0.872727
51 GLU GLU TYR LEU GLN ALA PHE THR TYR 0.485714 0.704918
52 PHE LEU ARG GLY ARG ALA TYR GLY LEU 0.485714 0.806452
53 SER SER THR ARG GLY ILE SER GLN LEU TRP 0.484076 0.846154
54 THR ARG ARG GLU THR GLN LEU 0.483871 0.877193
55 ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE 0.482517 0.847458
56 ARG ABA GLN ILE PHE ALA ASN ILE 0.481752 0.785714
57 LYS VAL ILE THR PHE ILE ASP LEU 0.481481 0.807018
58 PHE ARG TYR LEU GLY 0.480916 0.790323
59 ASP PHE GLU GLU ILE 0.478992 0.709091
60 LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE 0.476821 0.793651
61 ACE ALC ARG ALA MET CY1 SER LEU NH2 0.472222 0.83871
62 LEU ASP GLU GLU THR GLY GLU PHE LEU 0.470588 0.807018
63 ARG GLN ALA SEP LEU SER ILE SER VAL 0.468531 0.83871
64 GLN PHE LYS ASP ASN VAL ILE LEU LEU 0.468531 0.775862
65 GLU VAL ASN 1OL ALA GLU PHE 0.468085 0.724138
66 LEU ALA ILE TYR SER 0.467742 0.694915
67 THR PHE GLN ALA PSA LEU ARG GLU 0.467105 0.883333
68 GLU LEU ASN ARG LYS MET ILE TYR MET 0.467105 0.787879
69 ASP ALA GLU PHE ARG HIS ASP 0.466667 0.71875
70 SER LEU PHE ASN THR VAL ALA THR LEU 0.466667 0.77193
71 GLY ALA ALA ARG ALA GLU VAL TYR LEU ARG 0.466216 0.819672
72 PHE GLU ALA ASN GLY ASN LEU ILE 0.464286 0.775862
73 ACE VAL PHE PHE ALA GLU ASP NH2 0.464 0.649123
74 ILE LEU ALA LYS PHE LEU HIS THR LEU 0.462585 0.681818
75 GLY ASN TYR SER PHE TYR ALA LEU 0.462121 0.714286
76 PRO LEU GLU PSA ARG LEU 0.458904 0.825397
77 ASP PHE SER ILE 0.457627 0.781818
78 SER SER ARG LYS GLU TYR TYR ALA 0.457364 0.746032
79 ASP ALA ASP GLU TYR LEU 0.456693 0.677966
80 SER GLN LEU LYS ASN ASN ALA LYS GLU ILE 0.455224 0.779661
81 PHE TYR ALA PRO GLU PRO ILE THR SER LEU 0.45283 0.64
82 ALA THR ARG ASN PHE SER GLY 0.452555 0.87931
83 ILE LEU ALA LYS PHE LEU HIS ARG LEU 0.450331 0.707692
84 ACE ILE TYR GLU SER LEU 0.448819 0.762712
85 GLU LEU LYS TPO GLU ARG TYR 0.448276 0.764706
86 LEU PRO PHE ASP ARG THR THR ILE MET 0.447205 0.739726
87 SER HIS VAL ALA VAL GLU ASN ALA LEU 0.446809 0.730159
88 ARG GLY PHE ALA LEU M3L SER THR HIS GLY 0.445122 0.697368
89 ILE LEU GLY LYS PHE LEU HIS ARG LEU 0.443709 0.742424
90 SER LEU TYR ASN THR ILE ALA THR LEU 0.442029 0.766667
91 SER GLN TYR TYR TYR ASN SER LEU 0.44186 0.741935
92 MET PHE SER ILE ASP ASN ILE LEU ALA 0.441379 0.770492
93 ACE ALA ARG THR GLU VAL TYR NH2 0.441176 0.864407
94 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.440252 0.782609
95 ARG PRO GLY ASN PHE LEU GLN ASN ARG PRO 0.439716 0.842105
96 ARG LEU GLN ARG ARG ARG GLU THR GLN VAL 0.439394 0.877193
97 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.438596 0.628205
98 GLU GLN TYR LYS PHE TYR SER VAL 0.437956 0.730159
99 SER GLU ASP GLU PHE TYR ASP ALA LEU SER 0.4375 0.737705
100 ARG ARG PHE AIB ALA MET LEU ALA 0.4375 0.774194
101 LYS ILE LEU HIS ARG LEU LEU GLN ASP 0.43662 0.761905
102 ACE PHE LYS PHE TA2 ALA LEU ARG NH2 0.436242 0.777778
103 LEU GLU LEU ASP LYS TRP ALA SER LEU 0.436242 0.734375
104 GLY ALA ASP ILE PHE TYR LEU ASP GLY ALA 0.434783 0.645161
105 ALA ILE PHE GLN SER SER MET THR LYS 0.434483 0.774194
106 VAL GLN GLN GLU SER SER PHE VAL MET 0.433824 0.79661
107 GLY ASP GLU VAL LYS VAL PHE ARG 0.433566 0.827586
108 PRO ALA ILE LEU TYR ALA LEU LEU SER SER 0.433566 0.723077
109 ARG ASP ARG ALA ALA LYS LEU 0.433333 0.77193
110 ASP ARG VAL TYR ILE HIS PRO PHE 0.432749 0.671053
111 SER ARG LYS ILE ASP ASN LEU ASP 0.432624 0.881356
112 ALA THR VAL ARG THR TYR SER CYS 0.431655 0.866667
113 GLU GLU TYR LEU LYS ALA TRP THR PHE 0.43125 0.637681
114 SER PHE ALA ASN GLY 0.430894 0.736842
115 GLY GLY LYS LYS LYS TYR ARG LEU 0.42963 0.790323
116 GLY GLY ARG LYS LYS TYR LYS LEU 0.42963 0.790323
117 VAL LYS VAL VAL ALA LYS LYS TYR ARG ASN 0.42963 0.806452
118 GLY GLY LYS LYS ARG TYR LYS LEU 0.42963 0.790323
119 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 0.429487 0.738462
120 PRO GLU SEP LEU GLU SER CYS PHE 0.427536 0.730159
121 GLU LEU ASP 1OL VAL GLU PHE 0.426573 0.701754
122 SER SER VAL ILE GLY VAL TRP TYR LEU 0.425806 0.686567
123 GLU LEU ARG ARG LYS MET MET TYR MET 0.425532 0.769231
124 LEU GLU PHE GLN GLY 0.425197 0.75
125 ALA ALA SER LEU TYR GLU LYS LYS ALA ALA 0.42446 0.754098
126 ALA LEU PRO HIS ALA ILE LEU ARG LEU 0.424051 0.661972
127 LEU TYR LEU VAL CYS GLY GLU ARG VAL 0.423841 0.819672
128 VAL MET ALA PRO ARG THR LEU PHE LEU 0.42236 0.689189
129 ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 0.421687 0.782609
130 ALA ASN SER ARG TRP GLN ASP THR ARG LEU 0.421053 0.815385
131 GLU LEU ASP LYS TYR ALA SER 0.42029 0.766667
132 LYS LYS SER LYS THR LYS CYS VAL ILE PHE 0.419847 0.754386
133 ARG GLN ALA SEP ILE GLU LEU PRO SER MET 0.41954 0.679487
134 PHE LEU GLU LYS 0.419355 0.714286
135 PHE VAL PHE LEU GLU ILE NH2 0.419118 0.666667
136 SER PRO LYS ARG ILE ALA 0.41844 0.720588
137 ALA ARG THR MLY GLN THR ALA ARG TYR 0.417808 0.779412
138 VAL ALA ARG SER 0.417391 0.836364
139 SER LEU LYS ILE ASP ASN GLU ASP 0.417266 0.793103
140 LEU TYR LEU VAL CYS GLY GLU ARG GLY 0.417219 0.819672
141 ALA GLU THR PHE 0.416667 0.696429
142 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.416149 0.75
143 ARG TYR GLY PHE VAL ALA ASN PHE 0.416107 0.793651
144 GLU LEU GLU LYS TRP ALA SER 0.415493 0.676923
145 SER ILE TYR PHE TPO PRO GLU LEU TYR ASP 0.415205 0.620253
146 LYS ALA ARG VAL LEU ALA GLU ALA MET SER 0.414286 0.762712
147 LYS ALA ARG VAL LEU ALA GLU ALA MET 0.414286 0.762712
148 VAL ARG SER ARG ARG ABA LEU ARG LEU 0.414062 0.910714
149 HIS LYS ILE LEU HIS ARG LEU LEU GLN ASP 0.414013 0.753846
150 LYS ILE LEU HIS ARG LEU LEU GLN ASP SER 0.4125 0.8125
151 GLY ARG PHE GLN VAL THR 0.412214 0.803571
152 GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 0.412162 0.727273
153 PHE ALA GLY LEU ARG GLN ALA VAL THR GLN 0.411765 0.859649
154 GLY ALA PHE THR PHE ASN GLU ASP PHE 0.411765 0.666667
155 PHQ ILE ALA ARG SER 0.411348 0.684211
156 DTY ILE ARG LEU LPD 0.410959 0.676056
157 ILE ARG ALA ALA PRO PRO PRO LEU PHE 0.410256 0.7
158 GLU THR LEU LEU ASP LEU ASP PHE LEU GLU 0.409449 0.678571
159 VAL ARG SER ARG ARG CYS LEU ARG LEU 0.409449 0.877193
160 ILE GLY PRO GLY ARG ALA PHE TYR THR ILE 0.409357 0.712329
161 ALA ILE ARG SER 0.408333 0.836364
162 SER LEU TYR LEU THR VAL ALA THR LEU 0.407407 0.711864
163 LEU PRO PHE ASP LYS SER THR ILE MET 0.407186 0.657534
164 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.407186 0.630137
165 LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.406977 0.712329
166 ASN TYR THR PRO GLY PRO GLY ILE ARG PHE 0.406977 0.693333
167 SER ASP ILE LEU PHE PRO ALA ASP SER 0.406667 0.716418
168 TYR GLN GLU SER THR ASP PHE THR PHE LEU 0.40625 0.689655
169 TYR ASP GLN ILE LEU 0.406015 0.694915
170 GLY GLN VAL PRO PHE SER LYS GLU GLU CYS 0.405797 0.68254
171 SER PHE PHE GLU ASP ASN PHE VAL PRO GLU 0.405405 0.661972
172 ALA ASN SER ARG VAL PRO THR SER ILE ILE 0.405405 0.764706
173 SER LEU LEU MET TRP ILE THR GLN LEU 0.405229 0.705882
174 ASN GLN LEU ALA TRP PHE ASP THR ASP LEU 0.405063 0.661538
175 GLU LEU ASP NRG TRP ALA SER 0.405063 0.726027
176 LEU PRO PHE GLU LYS SER THR VAL MET 0.404908 0.643836
177 SER HIS MET ALA GLU ILE 0.404255 0.671642
178 GLY ILE LEU GLY PHE VAL PHE THR LEU 0.404255 0.745763
179 HIS VAL ALA VAL GLU ASN ALA LEU 0.404255 0.634921
180 PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE 0.40411 0.761905
181 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.403846 0.702703
182 LEU ALA SER LEU GLU SER GLN SER 0.403226 0.8
183 PHE LEU SER TYR LYS 0.402985 0.725806
184 PHE LEU ALA TYR LYS 0.402985 0.645161
185 THR GLU ASN LEU TYR PHE GLN SER GLY THR 0.402597 0.761905
186 ARG PHE MET ASP TYR TRP GLU GLY LEU 0.402367 0.694444
187 ARG GLU ALA ALA 0.401709 0.781818
188 ALA ARG THR M3L GLN THR ALA ARG 0.40146 0.746269
189 GLY ILE LEU GLY LEU VAL PHE THR LEU 0.401408 0.77193
190 TYR PRO LYS ARG ILE ALA 0.401316 0.666667
191 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.4 0.690141
192 TYR SER THR CYS TYR PHE ILE MET 0.4 0.661538
193 THR ASN GLU PHE TYR ALA 0.4 0.66129
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1LEK; Ligand: GLU GLN TYR LYS PHE TYR SER VAL; Similar sites found: 53
This union binding pocket(no: 1) in the query (biounit: 1lek.bio1) has 62 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1TV5 N8E 0.004189 0.48984 4.0404
2 4DOO DAO 0.04304 0.41292 4.0404
3 3RV5 DXC 0.01086 0.43615 4.49438
4 3TKA CTN 0.0253 0.45221 5.10949
5 5H9Q TD2 0.01072 0.44654 5.16129
6 4B1X LAB 0.03656 0.42702 6.06061
7 2A3I C0R 0.01261 0.42495 6.06061
8 2Q1H AS4 0.029 0.41299 6.06061
9 5HCV 60R 0.03324 0.40735 6.06061
10 3SP6 IL2 0.03972 0.40615 6.06061
11 4UDB CV7 0.02346 0.40466 6.06061
12 5F74 AMP 0.003857 0.487 6.09756
13 5V4R MGT 0.01437 0.45501 6.17284
14 3OKI OKI 0.03017 0.40942 6.86695
15 2PRG BRL 0.03733 0.41026 7.01107
16 4MG7 27H 0.01893 0.42524 7.07071
17 3UUD EST 0.02591 0.42461 7.07071
18 2BJ4 OHT 0.0178 0.42061 7.07071
19 5DXE EST 0.03299 0.41906 7.07071
20 2QZO KN1 0.02764 0.41403 7.07071
21 5B25 4QJ 0.04084 0.41112 7.07071
22 4E2J MOF 0.02215 0.41068 7.07071
23 5K53 STE 0.03852 0.40421 7.07071
24 5UFS 1TA 0.03576 0.40085 7.07071
25 1N5S ADL 0.009275 0.44436 7.14286
26 4WVW SLT 0.01099 0.45534 7.63889
27 3SQP 3J8 0.02152 0.44765 7.94979
28 3KYQ DPV 0.04091 0.42808 8.08081
29 4P42 PEE 0.0185 0.40936 8.08081
30 3KMZ EQO 0.01681 0.40656 8.08081
31 5T7I LAT NAG GAL 0.02792 0.43764 8.3871
32 1QKQ MAN 0.001932 0.49812 8.4507
33 2J3M ATP 0.02224 0.41059 9.09091
34 2J3M PRI 0.02186 0.40846 9.09091
35 3OYW TDG 0.02075 0.44514 9.70149
36 2ZHL NAG GAL GAL NAG 0.0479 0.41354 10.101
37 3N7S 3N7 0.04561 0.42561 10.4167
38 5LX9 OLB 0.03635 0.41682 12.1212
39 3GZ8 APR 0.04073 0.40053 12.3457
40 3PQB VGP 0.02696 0.40917 13.1313
41 3TAY MN0 0.01868 0.40455 14.1104
42 2QFY AKG 0.02294 0.41162 14.1414
43 4P6W MOF 0.0243 0.40878 14.1414
44 1M2Z DEX 0.03671 0.40523 14.1414
45 4QVX 3CQ 0.04128 0.40273 14.1414
46 4DK7 0KS 0.01441 0.42807 15.1515
47 4WOE ADP 0.04524 0.42679 16.1616
48 4RW3 PLM 0.04314 0.43582 17.8832
49 5N18 8HZ 0.0496 0.42564 19.1919
50 5LWY OLB 0.02998 0.42125 21.8487
51 4K55 H6P 0.008825 0.47085 23.2323
52 3RY9 1CA 0.045 0.40611 24.2424
53 5OCA 9QZ 0.00447 0.47168 33.3333
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