Receptor
PDB id Resolution Class Description Source Keywords
1RJE 2 Å EC: 2.1.1.- STRUCTURE OF PPM1, A LEUCINE CARBOXY METHYLTRANSFERASE INVOLVED IN THE REGULATION OF PROTEIN PHOSPHATASE 2A A CTIVITY SACCHAROMYCES CEREVISIAE SAM DEPENDENT METHYLTRANSFERASE
Ref.: STRUCTURE OF PROTEIN PHOSPHATASE METHYLTRANSFERASE 1 (PPM1), A LEUCINE CARBOXYL METHYLTRANSFERASE INVOLVED IN THE REGULATION OF PROTEIN PHOSPHATASE 2A ACTIVITY. J.BIOL.CHEM. V. 279 8351 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BME A:1004;
A:1007;
B:1005;
B:1008;
C:1006;
C:1009;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
78.133 C2 H6 O S C(CS)...
SAH A:2001;
B:2002;
C:2003;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
SO4 A:1001;
B:1002;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1RJD 1.8 Å EC: 2.1.1.- STRUCTURE OF PPM1, A LEUCINE CARBOXY METHYLTRANSFERASE INVOLVED IN THE REGULATION OF PROTEIN PHOSPHATASE 2A A CTIVITY SACCHAROMYCES CEREVISIAE SAM DEPENDENT METHYLTRANSFERASE
Ref.: STRUCTURE OF PROTEIN PHOSPHATASE METHYLTRANSFERASE 1 (PPM1), A LEUCINE CARBOXYL METHYLTRANSFERASE INVOLVED IN THE REGULATION OF PROTEIN PHOSPHATASE 2A ACTIVITY J.BIOL.CHEM. V. 279 8351 2004
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 57 families.
1 1RJE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1RJD - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2OB2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 50 families.
1 1RJE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1RJD - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2OB2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 1RJE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1RJD - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2OB2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1RJD; Ligand: SAM; Similar sites found: 229
This union binding pocket(no: 1) in the query (biounit: 1rjd.bio3) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5BW4 SAM 0.00003704 0.50835 None
2 3LCV SAM 0.0000001975 0.59258 0.711744
3 1TZD ADP 0.01259 0.4227 0.727273
4 3LST SAH 0.0000005448 0.60549 1.49701
5 1FP1 SAH 0.0000001542 0.55486 1.49701
6 4KRG SAH 0.000001185 0.53176 1.49701
7 5E72 SAM 0.0007617 0.43952 1.49701
8 3UCL FAD 0.03483 0.4044 1.49701
9 3UCL NAP 0.03771 0.4044 1.49701
10 3UCL CYH 0.03483 0.4044 1.49701
11 1NW5 SAM 0.003179 0.41513 1.5674
12 3VYW SAM 0.004916 0.40379 1.62338
13 1TPY SAH 0.0002417 0.46042 1.74216
14 1QZZ SAM 0.00003976 0.519 1.79641
15 3Q9T FAY 0.01594 0.40248 1.79641
16 5EB4 FAD 0.01966 0.40025 1.79641
17 1J0X NAD 0.01896 0.40361 1.80723
18 5THQ NDP 0.005748 0.41307 1.83824
19 2UYQ SAM 0.000000009322 0.74818 1.93548
20 3TN7 NJP 0.0008453 0.45068 1.94553
21 1FK8 NAD 0.001352 0.40428 1.94553
22 1PR9 NAP 0.001552 0.44184 2.04918
23 3TKY SAH 0.000000327 0.57002 2.09581
24 1XDS SAM 0.00001491 0.53877 2.09581
25 4KRI SAH 0.000004115 0.53209 2.09581
26 4AZT SAM 0.00002879 0.5075 2.09581
27 4AZW SAM 0.00003309 0.49949 2.09581
28 4E70 N7I 0.00000983 0.45564 2.09581
29 5F2K OCA 0.00003684 0.42685 2.09581
30 5F2K SAH 0.00003684 0.42685 2.09581
31 4J1Q NDP 0.005816 0.41014 2.09581
32 1TV5 N8E 0.01972 0.40912 2.09581
33 1TV5 A26 0.01765 0.40333 2.09581
34 2GDZ NAD 0.001732 0.43571 2.24719
35 4NEC SAH 0.000000948 0.58646 2.27273
36 5JBX MLI 0.02573 0.40324 2.29885
37 2WPB ZZI 0.007547 0.43076 2.30263
38 4PNE SAH 0.000004899 0.51099 2.31788
39 3AFN NAP 0.006789 0.41363 2.32558
40 1Z3C SA8 0.0001144 0.42138 2.34899
41 2ZIF SAM 0.006112 0.40303 2.3569
42 4N49 SAM 0.003501 0.40995 2.39521
43 3TKA SAM 0.005912 0.40044 2.39521
44 3GCZ SAM 0.0007052 0.42929 2.48227
45 3LKZ SFG 0.0006416 0.44472 2.49221
46 2BGM NAJ 0.002545 0.42411 2.51799
47 2BZG SAH 0.0005209 0.45287 2.58621
48 2P41 SAH 0.0008725 0.44314 2.62295
49 1XHL NDP 0.0008371 0.45226 2.6936
50 5X62 SAH 0.000008487 0.53675 2.69461
51 1G55 SAH 0.0003177 0.45771 2.69461
52 3K8L CEY 0.01278 0.42781 2.69461
53 5UAO FAD 0.009339 0.41292 2.69461
54 4USQ FAD 0.009178 0.409 2.69461
55 2AOT SAH 0.00007723 0.45571 2.73973
56 1JQD SAH 0.000472 0.40259 2.73973
57 1JQD HSM 0.001161 0.40166 2.73973
58 5XVK SAH 0.000007421 0.50448 2.8169
59 4D42 W0I 0.006346 0.43048 2.83688
60 4D42 NAP 0.006346 0.43048 2.83688
61 1I9G SAM 0.005816 0.40074 2.85714
62 2WA2 SAM 0.0003486 0.43597 2.89855
63 1RSG FAD 0.009127 0.41722 2.90698
64 3EVG SAH 0.0005181 0.45298 2.90909
65 3BXO SAM 0.00004663 0.51579 2.92887
66 3H2B SAH 0.00003559 0.49815 2.95567
67 2YX1 SFG 0.001054 0.45291 2.99401
68 2AE2 NAP 0.001647 0.44888 3.07692
69 1NFQ NAI 0.003614 0.42444 3.07692
70 4NBW NAD 0.001408 0.43668 3.11284
71 5FTW SAH 0.000001236 0.55386 3.125
72 1L1E SAH 0.0001275 0.46994 3.13589
73 5GWX SAM 0.0004265 0.41905 3.16901
74 5GWX SAR 0.0004265 0.41905 3.16901
75 5XLX SAH 0.0001016 0.46339 3.19149
76 3DXY SAM 0.00001769 0.54224 3.21101
77 3OU2 SAH 0.0000004771 0.52871 3.21101
78 3G5K BB2 0.008416 0.40723 3.27869
79 4LWP SAH 0.00007114 0.46683 3.29341
80 5HJM MTA 0.0004094 0.45302 3.29341
81 3S1S SAH 0.0003698 0.43693 3.29341
82 1Y9G FRU 0.02074 0.4081 3.29341
83 1R6D NAD 0.02654 0.40374 3.29341
84 1YXM ADE 0.0001391 0.52786 3.30033
85 1SNY NAP 0.004838 0.41215 3.37079
86 2PWY SAH 0.001994 0.42375 3.48837
87 4OBW SAM 0.0002942 0.46365 3.50195
88 1G0N PHH 0.003239 0.43666 3.53357
89 1G0N NDP 0.00298 0.43517 3.53357
90 3QOX SAH 0.00002388 0.50479 3.59281
91 1O5I NAD 0.002972 0.41638 3.61446
92 1ICV NIO 0.02269 0.40384 3.68664
93 1F3L SAH 0.0003332 0.44599 3.73832
94 5JGL SAM 0.00002839 0.51347 3.80623
95 3RKR NAP 0.0002595 0.49277 3.81679
96 1KYZ SAH 0.000006753 0.53486 3.89222
97 1KYZ FER 0.0001165 0.43243 3.89222
98 5JE0 AZ8 0.00008949 0.42384 3.89222
99 5JE0 SAH 0.00008949 0.42384 3.89222
100 1H9A NAP 0.005846 0.41767 3.89222
101 2CDU FAD 0.006833 0.4169 3.89222
102 3FZG SAM 0.0000423 0.51161 4
103 2AG5 NAD 0.002941 0.42572 4.06504
104 4BLW AMP 0.003083 0.42995 4.15225
105 4BLW SAH 0.002138 0.42736 4.15225
106 4YMH SAH 0.002141 0.41886 4.16667
107 3P13 RIP 0.011 0.41754 4.16667
108 1KPH SAH 0.0002453 0.46016 4.18118
109 1KPG SAH 0.0002182 0.45339 4.18118
110 2A14 SAH 0.0000824 0.47106 4.18251
111 5THZ SAH 0.000003176 0.54173 4.19162
112 5THY SAH 0.000002448 0.54148 4.19162
113 1I8T FAD 0.003524 0.43297 4.19162
114 1XTP SAI 0.00008167 0.48783 4.33071
115 3QWI CUE 0.002018 0.44595 4.44444
116 3QWI NAP 0.001167 0.44595 4.44444
117 4URN NOV 0.01042 0.42469 4.44444
118 1UAY ADN 0.003903 0.4265 4.54545
119 1J1R ADE 0.01244 0.42044 4.5977
120 1ZGA SAH 0.000001951 0.57977 4.7619
121 5F8F SFG 0.0000001281 0.6259 4.79042
122 5JJR SAH 0.0009919 0.44072 4.79042
123 1N4W FAD 0.01022 0.41589 4.79042
124 2YY7 NAD 0.002493 0.43019 4.80769
125 1BC5 SAH 0.000006362 0.50767 4.83271
126 3T7S SAM 0.00001197 0.50093 4.85075
127 1G60 SAM 0.0009098 0.43826 5
128 1Q0S SAH 0.001325 0.40854 5.01931
129 4Q9N NAI 0.004425 0.41932 5.03356
130 3MQ2 SAH 0.00005888 0.49941 5.04587
131 4A6D SAM 0.000002252 0.54914 5.08982
132 5MPT SAH 0.000003405 0.54778 5.08982
133 4KIB SAH 0.00003492 0.47358 5.08982
134 1U2Z SAH 0.0002985 0.45854 5.08982
135 4MIG G3F 0.0152 0.41211 5.08982
136 2PX8 SAH 0.001143 0.43804 5.20446
137 4PIO SAH 0.00004691 0.51013 5.26316
138 4PIO AVI 0.00004917 0.50771 5.26316
139 5XVQ SAH 0.00001695 0.49038 5.28169
140 4XCP PLM 0.02011 0.41007 5.29412
141 1FWM CB3 0.009743 0.408 5.30303
142 3P2E SAH 0.00008949 0.47634 5.33333
143 5DX8 SFG 0.0003125 0.44236 5.38922
144 5DXA SFG 0.0004217 0.43584 5.38922
145 5DX1 SFG 0.0002284 0.43578 5.38922
146 5DWQ SFG 0.0003497 0.43307 5.38922
147 5DX0 SFG 0.0003701 0.42839 5.38922
148 5ULP KB1 0.0001569 0.44575 5.59701
149 5IL1 SAM 0.0006128 0.44981 5.66038
150 5FA5 MTA 0.0001982 0.48117 5.68862
151 4GQB 0XU 0.00009592 0.45455 5.68862
152 5DNK SAH 0.00003404 0.45081 5.68862
153 3MJE NDP 0.008024 0.40676 5.68862
154 2VDV SAM 0.00001786 0.53513 5.69106
155 1JA9 NDP 0.001287 0.44409 5.83942
156 1RL4 BRR 0.009209 0.42631 5.85106
157 4N9Z V3L 0.002323 0.46695 5.98802
158 1QO8 FAD 0.01034 0.41476 5.98802
159 4RDH AMP 0.01068 0.40251 6.25
160 2V6G NAP 0.0003955 0.46506 6.28743
161 3TTM PUT 0.01982 0.40727 6.28743
162 5K7U SAM 0.000798 0.44483 6.30372
163 3G2O SAM 0.00001129 0.52516 6.35452
164 5CUQ NSC 0.001513 0.44101 6.36704
165 2XVM SAH 0.000000001098 0.62105 6.53266
166 3BGD SAH 0.0003805 0.43814 6.53846
167 3BGD PM6 0.0005636 0.41125 6.53846
168 1QAN SAH 0.0001725 0.4568 6.55738
169 5KOK SAH 0.0000002548 0.5894 6.58683
170 5KOK R9T 0.00000147 0.46116 6.58683
171 5KOK S9T 0.000001277 0.45753 6.58683
172 4UCI SAM 0.003854 0.41157 6.58683
173 3OJF NDP 0.01347 0.40269 6.61479
174 4II2 ATP 0.001781 0.42219 6.74847
175 3HVJ 705 0.0005458 0.46695 6.78733
176 3H8V ATP 0.001328 0.43521 6.84932
177 3CTY FAD 0.01916 0.40425 6.89655
178 1VE3 SAM 0.00000871 0.53006 7.04846
179 3C6K MTA 0.01239 0.40536 7.08661
180 3C6K SPD 0.01239 0.40536 7.08661
181 1LSS NAD 0.0009199 0.43416 7.14286
182 5L95 AMP 0.001224 0.43277 7.16846
183 3C3Y SAH 0.001599 0.42784 7.173
184 1AE1 NAP 0.001283 0.44547 7.32601
185 4R6W SAH 0.000006773 0.45226 7.36434
186 5E9W SAH 0.000000461 0.52042 7.37179
187 2W58 ADP 0.01673 0.41022 7.42574
188 2PXX SAH 0.000005083 0.5341 7.44186
189 3MB5 SAM 0.00006877 0.46557 7.45098
190 1Z6Z NAP 0.007385 0.40833 7.48503
191 5MGZ SAH 0.0001005 0.47897 7.62712
192 4DMG SAM 0.002547 0.43964 7.63359
193 1ORR NAD 0.01023 0.40578 7.78098
194 3PT9 SAH 0.001498 0.41582 7.78443
195 2Q2V NAD 0.01334 0.40068 7.84314
196 3X01 AMP 0.02138 0.4098 8.08383
197 1DMR PGD 0.03716 0.40416 8.08383
198 3JWH SAH 0.000002438 0.49766 8.29493
199 3AD8 FAD 0.04102 0.40152 8.38323
200 5LOG SAH 0.006406 0.40216 8.58369
201 4DCM SAM 0.00003156 0.51739 8.68263
202 2EJU SAH 0.002323 0.42465 8.73016
203 1SQF SAM 0.003682 0.41595 8.98204
204 5GM1 SAH 0.00001938 0.48748 9.09091
205 5FA8 SAM 0.000516 0.42746 9.31677
206 2DPM SAM 0.002902 0.40794 9.85915
207 1I1N SAH 0.003903 0.41761 10.177
208 4CVN ADP 0.02635 0.40271 10.4712
209 3P9C SAH 0.000006217 0.45029 10.479
210 5E1M SAH 0.00008586 0.41244 10.7884
211 5E1M PRO PRO LYS ARG ILE ALA 0.00008586 0.41244 10.7884
212 2F5Z FAD 0.01901 0.40356 10.9375
213 3GXO SAH 0.00001078 0.53854 11.0778
214 3GWZ SAH 0.000002934 0.50265 11.0778
215 3Q87 SAM 0.0003161 0.43961 11.2
216 1DCP HBI 0.02479 0.41559 11.5385
217 3A25 SAM 0.00518 0.4095 11.6279
218 3NUG NAD 0.004049 0.421 11.7409
219 1JG3 ADN 0.003533 0.41673 12.766
220 2ZFU SAH 0.000002691 0.53977 13.4884
221 2XRH NIO 0.01742 0.40328 14
222 1DL5 SAH 0.001861 0.42994 14.1956
223 4WH9 3M8 0.01704 0.40276 14.2077
224 1UZN NAP 0.002388 0.40002 14.5749
225 2HMT NAI 0.001578 0.41843 14.5833
226 1WZ1 DNS 0.01996 0.41043 15.0442
227 1V59 NAD 0.004682 0.42705 15.2695
228 2WSB NAD 0.00549 0.42531 16.9291
229 5E8J SAH 0.000001013 0.59298 22.7273
Pocket No.: 2; Query (leader) PDB : 1RJD; Ligand: SAM; Similar sites found: 38
This union binding pocket(no: 2) in the query (biounit: 1rjd.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3VSE SAH 0.001725 0.40633 1.1976
2 3GDN HBX 0.01494 0.41984 1.79641
3 3GDN FAD 0.01088 0.41984 1.79641
4 4ORM 2V6 0.03922 0.40585 2.09581
5 4ORM FMN 0.03922 0.40585 2.09581
6 4ORM ORO 0.03922 0.40585 2.09581
7 5N5D SAM 0.005724 0.4058 2.21239
8 3O26 NDP 0.01248 0.40437 2.2508
9 4LH7 1X8 0.02825 0.40007 2.78638
10 2WPF FAD 0.04763 0.41413 2.99401
11 1R6D DAU 0.02368 0.41085 3.29341
12 1SB8 NAD 0.03304 0.4009 3.29341
13 1SB8 UD2 0.03785 0.4009 3.29341
14 2GVC FAD 0.01801 0.40062 3.29341
15 1SQL GUN 0.02221 0.40362 3.42466
16 1R18 SAH 0.002903 0.40039 3.52423
17 3E8T UQ8 0.03557 0.40291 3.63636
18 4IRP UDP 0.01674 0.41139 3.89222
19 5TQZ GLC 0.02795 0.40387 4
20 4AT0 FAD 0.015 0.41743 4.11765
21 1ELI PYC 0.02232 0.40141 4.79042
22 2X1L MET 0.02322 0.40347 5.15267
23 1FEC FAD 0.0244 0.40649 5.38922
24 3ICR FAD 0.01877 0.40396 5.61225
25 4OYA 1VE 0.03347 0.40869 5.68862
26 4J36 FAD 0.018 0.40278 5.98802
27 4J36 1HR 0.02594 0.40278 5.98802
28 1SQS TLA 0.01749 0.40976 6.19835
29 3OJF IMJ 0.02411 0.40258 6.61479
30 3G6N MET ALA SER 0.0199 0.40563 6.80628
31 4O4Z N2O 0.01658 0.41293 7.14286
32 4USR FAD 0.01241 0.40805 7.18563
33 2GAG FAD 0.02294 0.40698 8.08383
34 2GAG FOA 0.02425 0.40582 8.08383
35 3AB4 LYS 0.005906 0.41054 10.1124
36 5IJJ I6P 0.0211 0.40658 10.9375
37 2C31 ADP 0.04875 0.40493 12.8743
38 2C31 TZD 0.04989 0.40493 12.8743
Pocket No.: 3; Query (leader) PDB : 1RJD; Ligand: SAM; Similar sites found: 5
This union binding pocket(no: 3) in the query (biounit: 1rjd.bio2) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1QMG DMV 0.005554 0.43785 2.09581
2 5EW0 3C7 0.02701 0.40052 5.98291
3 3BPX SAL 0.02356 0.40702 6.08108
4 1JJV ATP 0.01914 0.40899 9.2233
5 5N53 8NB 0.02917 0.40039 11.6766
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