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Receptor
PDB id Resolution Class Description Source Keywords
1RJE 2 Å EC: 2.1.1.- STRUCTURE OF PPM1, A LEUCINE CARBOXY METHYLTRANSFERASE INVOLVED IN THE REGULATION OF PROTEIN PHOSPHATASE 2A A CTIVITY SACCHAROMYCES CEREVISIAE SAM DEPENDENT METHYLTRANSFERASE
Ref.: STRUCTURE OF PROTEIN PHOSPHATASE METHYLTRANSFERASE 1 (PPM1), A LEUCINE CARBOXYL METHYLTRANSFERASE INVOLVED IN THE REGULATION OF PROTEIN PHOSPHATASE 2A ACTIVITY. J.BIOL.CHEM. V. 279 8351 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BME A:1004;
A:1007;
B:1005;
B:1008;
C:1006;
C:1009;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
78.133 C2 H6 O S C(CS)...
SAH A:2001;
B:2002;
C:2003;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
SO4 A:1001;
B:1002;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1RJD 1.8 Å EC: 2.1.1.- STRUCTURE OF PPM1, A LEUCINE CARBOXY METHYLTRANSFERASE INVOLVED IN THE REGULATION OF PROTEIN PHOSPHATASE 2A A CTIVITY SACCHAROMYCES CEREVISIAE SAM DEPENDENT METHYLTRANSFERASE
Ref.: STRUCTURE OF PROTEIN PHOSPHATASE METHYLTRANSFERASE 1 (PPM1), A LEUCINE CARBOXYL METHYLTRANSFERASE INVOLVED IN THE REGULATION OF PROTEIN PHOSPHATASE 2A ACTIVITY J.BIOL.CHEM. V. 279 8351 2004
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 1RJE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1RJD - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2OB2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 1RJE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1RJD - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2OB2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 1RJE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1RJD - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2OB2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1RJD; Ligand: SAM; Similar sites found with APoc: 545
This union binding pocket(no: 1) in the query (biounit: 1rjd.bio3) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 5BW4 SAM None
2 6CI9 NAP None
3 5T2U NAP None
4 6FX2 FUC C4W NAG BMA MAN NAG GAL None
5 1H5Q NAP None
6 3LCV SAM 0.711744
7 1TZD ADP 0.727273
8 3VSE SAH 1.1976
9 5CG1 NAD BBN 1.31148
10 5OJ7 AR6 1.3986
11 1FP1 SAH 1.49701
12 3LST SAH 1.49701
13 4KRG SAH 1.49701
14 6EL3 NAP 1.49701
15 5E72 SAM 1.49701
16 3QVP FAD 1.49701
17 3UCL FAD 1.49701
18 3UCL NAP 1.49701
19 3UCL CYH 1.49701
20 1QG6 TCL 1.53257
21 1QG6 NAD 1.53257
22 1NW5 SAM 1.5674
23 5W7M SAH 1.60256
24 3VYW SAM 1.62338
25 2E2P ADP 1.67224
26 1TPY SAH 1.74216
27 4JNA FAD 1.76471
28 1QZZ SAM 1.79641
29 5MLR GRQ 1.79641
30 5MLR NAP 1.79641
31 4HXY NDP 1.79641
32 2C5A NAD 1.79641
33 2C5A GDC 1.79641
34 1B4N GUA 1.79641
35 2BMB PMM 1.79641
36 3Q9T FAY 1.79641
37 2GN4 UD1 1.79641
38 5EB4 FAD 1.79641
39 1BDB NAD 1.80505
40 4K26 SFF 1.81159
41 4K26 NDP 1.81159
42 4XUC 43G 1.83486
43 4XUC SAM 1.83486
44 5Z75 NAD 1.83486
45 5THQ NDP 1.83824
46 3KO8 NAD 1.92308
47 2UYQ SAM 1.93548
48 3TN7 NJP 1.94553
49 1FK8 NAD 1.94553
50 2DKN NAI 1.96078
51 5Z2L NDP 2.04082
52 1PR9 NAP 2.04918
53 3D3W NAP 2.04918
54 3TKY SAH 2.09581
55 4KRI SAH 2.09581
56 5F2K OCA 2.09581
57 5F2K SAH 2.09581
58 4AZW SAM 2.09581
59 1XDS SAM 2.09581
60 4E70 N7I 2.09581
61 4Z24 FAD 2.09581
62 6F97 FAD 2.09581
63 1RJW ETF 2.09581
64 3AYI HCI 2.09581
65 4J1Q NDP 2.09581
66 1TV5 N8E 2.09581
67 5KMS NAD 2.09581
68 3AYI FAD 2.09581
69 5WGR FAD 2.09581
70 3HDY GDU 2.09581
71 5KMS FAD 2.09581
72 1TV5 A26 2.09581
73 5UFN SAH 2.10084
74 3FSY SCA 2.10843
75 3ZV6 NAD 2.13523
76 3ZV6 4HB 2.13523
77 2PT9 2MH 2.18069
78 2PT9 S4M 2.18069
79 1GZ6 NAI 2.19436
80 5O98 NAP 2.2082
81 5N5D SAM 2.21239
82 2GDZ NAD 2.24719
83 4NEC SAH 2.27273
84 2DTX BMA 2.27273
85 5JBX MLI 2.29885
86 2WPB ZZI 2.30263
87 2O07 SPD 2.30263
88 2O07 MTA 2.30263
89 1X1T NAD 2.30769
90 4PNE SAH 2.31788
91 3AFN NAP 2.32558
92 1Z3C SA8 2.34899
93 2ZIF SAM 2.3569
94 2Q46 NAP 2.37154
95 2JB2 PHE 2.39521
96 2JB2 FAD 2.39521
97 4MO2 FDA 2.39521
98 4N49 SAM 2.39521
99 4MO2 FAD 2.39521
100 2FR1 NDP 2.39521
101 3TKA SAM 2.39521
102 2BD0 NAP 2.45902
103 1Q7B NAP 2.45902
104 5F4B FMN 2.47525
105 3GCZ SAM 2.48227
106 3U4C NDP 2.4911
107 3LKZ SFG 2.49221
108 2BGM NAJ 2.51799
109 5GWT NAD 2.51799
110 5GWT SIN 2.51799
111 3A4V PYR 2.52366
112 3A4V NAD 2.52366
113 2BZG SAH 2.58621
114 5EJ2 NAD 2.5974
115 4Y9D NAI 2.62295
116 2P41 SAH 2.62295
117 3ELW SAM 2.66667
118 3ELW GP3 2.66667
119 2WYV NAD 2.68199
120 1XHL NDP 2.6936
121 6C5B SAH 2.69461
122 5ICE SAH 2.69461
123 5ICE 2H4 2.69461
124 5X62 SAH 2.69461
125 1G55 SAH 2.69461
126 5UAO FAD 2.69461
127 4USQ FAD 2.69461
128 2AOT SAH 2.73973
129 1JQD HSM 2.73973
130 1JQD SAH 2.73973
131 5YJI SAH 2.8169
132 5YJI 8WO 2.8169
133 4D42 NAP 2.83688
134 4D42 W0I 2.83688
135 1I9G SAM 2.85714
136 3EVF GTA 2.88809
137 3EVF SAH 2.88809
138 2WA2 SAM 2.89855
139 1WMA NDP 2.89855
140 1WMA AB3 2.89855
141 1RSG FAD 2.90698
142 3EVG SAH 2.90909
143 1YY5 FAD 2.92398
144 3BXO SAM 2.92887
145 3H2B SAH 2.95567
146 4GLL NAD 2.96736
147 6FDF SAH 2.99401
148 5HSA FAS 2.99401
149 5BJX NAD 2.99401
150 5BJX UDP 2.99401
151 1E5Q NDP 2.99401
152 2YX1 SFG 2.99401
153 2YVK MRU 2.99401
154 5J5Z FAD 2.99401
155 2IVD FAD 2.99401
156 5GT9 NAP 3.04183
157 4RVG SAM 3.05164
158 4RVG TYD 3.05164
159 5FJN BE2 3.07018
160 5FJN FAD 3.07018
161 2AE2 NAP 3.07692
162 2AE2 PTO 3.07692
163 1NFQ NAI 3.07692
164 4NBW NAD 3.11284
165 4YAG NAI 3.11419
166 5FTW SAH 3.125
167 1L1E SAH 3.13589
168 6HKE LMR 3.14465
169 3RJ5 NAD 3.14961
170 5GWX SAM 3.16901
171 5GWX SAR 3.16901
172 2WW4 ADP 3.18021
173 5XLX SAH 3.19149
174 2CFC NAD 3.2
175 3OU2 SAH 3.21101
176 3DXY SAM 3.21101
177 2EWM NAD 3.21285
178 2PD4 NAD 3.27273
179 2PD4 DCN 3.27273
180 3G5K BB2 3.27869
181 2JHP SAH 3.29341
182 4LWP SAH 3.29341
183 5HJM MTA 3.29341
184 1UWK URO 3.29341
185 1UWK NAD 3.29341
186 3S1S SAH 3.29341
187 4RPL FAD 3.29341
188 4RPL 3UC 3.29341
189 4NTD FAD 3.29341
190 1Y9G FRU 3.29341
191 1E1M NAP 3.29341
192 1E1M FAD 3.29341
193 1E6E FAD 3.29341
194 1R6D NAD 3.29341
195 1YXM ADE 3.30033
196 4YAC NAI 3.367
197 1VL8 NAP 3.37079
198 1SNY NAP 3.37079
199 1SQL GUN 3.42466
200 5L4S 6KX 3.45912
201 5L4S NAP 3.45912
202 1V7Z CRN 3.46154
203 6ECU SAH 3.48101
204 2PWY SAH 3.48837
205 6ECW SAH 3.49206
206 3CH6 NAP 3.4965
207 3CH6 311 3.4965
208 4OBW SAM 3.50195
209 3VZS NAP 3.50195
210 6AYI C3G 3.51759
211 1R18 SAH 3.52423
212 3ICC NAP 3.52941
213 1G0N PHH 3.53357
214 1G0N NDP 3.53357
215 4FN4 NAD 3.54331
216 4JE7 BB2 3.5533
217 4ZA2 NAD 3.55731
218 1XG5 NAP 3.58423
219 6C8R SAH 3.59281
220 3QOX SAH 3.59281
221 5FUB SAH 3.59281
222 5MW4 5JU 3.59281
223 3V1U NAD 3.59281
224 6C8R EQV 3.59281
225 5N0J FAD 3.59281
226 3HQ9 OXL 3.59281
227 6ER9 FAD 3.59281
228 6ER9 NAP 3.59281
229 5IM3 DTP 3.59281
230 4NBU NAI 3.6
231 6DUB SAH 3.6036
232 1O5I NAD 3.61446
233 6F9Q NAD 3.67647
234 1ICV NIO 3.68664
235 1EDO NAP 3.68852
236 6ECT SAM 3.73832
237 1F3L SAH 3.73832
238 1IY8 NAD 3.74532
239 5JGL SAM 3.80623
240 3RKR NAP 3.81679
241 1KYZ SAH 3.89222
242 5ERG SAM 3.89222
243 1KYZ FER 3.89222
244 5JE0 AZ8 3.89222
245 5JE0 SAH 3.89222
246 1H9A NAP 3.89222
247 2CDU FAD 3.89222
248 1GPE FAD 3.89222
249 2XVE FAD 3.89222
250 2XVF FAD 3.89222
251 1N7G NDP 3.89222
252 3MAG SAH 3.90879
253 3WXB NDP 3.94265
254 1V35 NAI 3.95137
255 2VPY MGD 3.95257
256 5I7S E9P 3.98551
257 5I7S NAD 3.98551
258 3FZG SAM 4
259 1D4D FAD 4.02098
260 4URF NAD 4.03226
261 3MCT SAH 4.0404
262 2AG5 NAD 4.06504
263 4BLW AMP 4.15225
264 4BLW SAH 4.15225
265 4YMH SAH 4.16667
266 3P13 RIP 4.16667
267 1KPG SAH 4.18118
268 1KPH SAH 4.18118
269 2A14 SAH 4.18251
270 5THY SAH 4.19162
271 5THZ SAH 4.19162
272 1I8T FAD 4.19162
273 4MOP 2H5 4.19162
274 1XCL SAH 4.25532
275 3A28 NAD 4.26357
276 5YSS NAD 4.29688
277 1XTP SAI 4.33071
278 3SHR CMP 4.34783
279 3QWI NAP 4.44444
280 3QWI CUE 4.44444
281 4URN NOV 4.44444
282 4BUZ OCZ 4.47154
283 4BUZ NAD 4.47154
284 4BUZ OAD 4.47154
285 3ABI NAD 4.49102
286 2Q0L FAD 4.50161
287 6BQ6 TER 4.53172
288 1UAY ADN 4.54545
289 1T0S BML 4.54545
290 1J1R ADE 4.5977
291 3OID NDP 4.65116
292 1L3I SAH 4.6875
293 1ZGA SAH 4.7619
294 5F8F SFG 4.79042
295 5T67 JHZ 4.79042
296 5T67 SAH 4.79042
297 5JJR SAH 4.79042
298 3FPF TNA 4.79042
299 3FPF MTA 4.79042
300 5FAG PPI 4.79042
301 2V3V MGD 4.79042
302 2YY7 NAD 4.80769
303 1BC5 SAH 4.83271
304 3T7S SAM 4.85075
305 2Q7V FAD 4.92308
306 1NJR XYL 4.92958
307 4YUW 4JU 4.93421
308 4YUW S4M 4.93421
309 1E3W NAD 4.98084
310 5K4W THR 4.98442
311 5K4W NAI 4.98442
312 1G60 SAM 5
313 1E6W NAD 5
314 1Q0S SAH 5.01931
315 1P1C SAH 5.02513
316 4Q9N NAI 5.03356
317 3MQ2 SAH 5.04587
318 5W7R SAH 5.08982
319 4A6D SAM 5.08982
320 5MPT SAH 5.08982
321 4KIB SAH 5.08982
322 5XNC MTA 5.08982
323 1U2Z SAH 5.08982
324 4MIG G3F 5.08982
325 5W7R 9Z7 5.08982
326 6B92 SAH 5.10204
327 5MTE BB2 5.10949
328 4ZRN NAD 5.12821
329 2PX8 SAH 5.20446
330 4PIO AVI 5.26316
331 4PIO SAH 5.26316
332 5YJF 8WO 5.28169
333 5YJF SAH 5.28169
334 4XCP PLM 5.29412
335 1FWM CB3 5.30303
336 3P2E SAH 5.33333
337 1U7T TDT 5.36398
338 1FP2 SAH 5.38922
339 1FP2 HMO 5.38922
340 6ARJ BW4 5.38922
341 6ARJ SAH 5.38922
342 5DX8 SFG 5.38922
343 5DXA SFG 5.38922
344 5DX0 SFG 5.38922
345 5DX1 SFG 5.38922
346 5DWQ SFG 5.38922
347 1EK6 UPG 5.38922
348 1EK6 NAI 5.38922
349 4XQC 13D 5.38922
350 2WET FAD 5.38922
351 4XQC NAD 5.38922
352 5BVA FAD 5.38922
353 1FEC FAD 5.38922
354 2OBF F83 5.53633
355 2OBF SAH 5.53633
356 1C9K 5GP 5.55556
357 5ULP KB1 5.59701
358 5IL1 SAM 5.66038
359 1FUT 2GP 5.66038
360 3KIF GDL 5.66038
361 4GQB 0XU 5.68862
362 5FA5 MTA 5.68862
363 5DNK SAH 5.68862
364 5XWV 8H6 5.68862
365 5XWV NDP 5.68862
366 4C3Y ANB 5.68862
367 4C3Y FAD 5.68862
368 2NYA MGD 5.68862
369 5ZYN FAD 5.68862
370 4NTC FAD 5.68862
371 5JAQ NAI 5.68862
372 2VDV SAM 5.69106
373 3PFG SAM 5.70342
374 3PFG TLO 5.70342
375 1XKQ NDP 5.71429
376 4CQM NAP 5.74713
377 2RH4 EMO 5.77617
378 4O0L NDP 5.81818
379 1JA9 NDP 5.83942
380 1RL4 BRR 5.85106
381 5WUW NAP 5.92335
382 4ITU 1HS 5.94796
383 4ITU NAI 5.94796
384 6GFK SAH 5.9761
385 5VN0 FAD 5.98802
386 5VN0 NAI 5.98802
387 5NMX NAP 5.98802
388 5NMX FAD 5.98802
389 5WXU FLC 5.98802
390 1QO8 FAD 5.98802
391 4O1M NAD 6.03175
392 2JAH NDP 6.07287
393 2JAP NDP 6.07287
394 3SJU NDP 6.09319
395 1XSE NDP 6.1017
396 3HB5 NAP 6.11621
397 4X7Y SAH 6.20438
398 1GEG NAD 6.25
399 4RDH AMP 6.25
400 2V6G NAP 6.28743
401 5U19 SAH 6.28743
402 5U19 827 6.28743
403 5YF1 SFG 6.28743
404 5YF1 8V0 6.28743
405 3L9W AMP 6.28743
406 3WMX NAD 6.28743
407 3TTM PUT 6.28743
408 4YNU LGC 6.28743
409 4YNU FAD 6.28743
410 1Q1R FAD 6.28743
411 3WGT FAD 6.28743
412 3WGT QSC 6.28743
413 3L9W GSH 6.28743
414 5K7U SAM 6.30372
415 3G2O SAM 6.35452
416 5CUQ NSC 6.36704
417 5TVI O8N 6.52174
418 2XVM SAH 6.53266
419 3BGD SAH 6.53846
420 3BGD PM6 6.53846
421 5B4T NAD 6.53846
422 5B4T 3HR 6.53846
423 1QAN SAH 6.55738
424 5KOK SAH 6.58683
425 5KOK R9T 6.58683
426 5KOK S9T 6.58683
427 6B3A SAM 6.58683
428 5OC1 FAD 6.58683
429 2Z3Y F2N 6.58683
430 4UCI SAM 6.58683
431 5MBX SP5 6.58683
432 5MBX FAD 6.58683
433 3OJF IMJ 6.61479
434 3OJF NDP 6.61479
435 4II2 ATP 6.74847
436 3HVJ 705 6.78733
437 5BSZ SAH 6.8
438 3H8V ATP 6.84932
439 2B4Q NAP 6.88406
440 5FWA J7C 6.88623
441 5K0A FAD 6.88623
442 2E7Z MGD 6.88623
443 3CTY FAD 6.89655
444 4ZJS 4P0 6.95652
445 1ZBQ NAD 7.03364
446 1VE3 SAM 7.04846
447 3C6K SPD 7.08661
448 3C6K MTA 7.08661
449 1LSS NAD 7.14286
450 5L95 AMP 7.16846
451 3C3Y SAH 7.173
452 5FEU NAP 7.2165
453 5O42 NAD 7.29927
454 5O42 9JW 7.29927
455 5O42 BGC 7.29927
456 1AE1 NAP 7.32601
457 6F5Z SAH 7.35931
458 4R6W PC 7.36434
459 4R6W SAH 7.36434
460 5E9W SAH 7.37179
461 5W7K SAH 7.37179
462 3ML1 MGD 7.40741
463 2W58 ADP 7.42574
464 2PXX SAH 7.44186
465 3MB5 SAM 7.45098
466 4J7U YTZ 7.48503
467 1Z6Z NAP 7.48503
468 4J7U NAP 7.48503
469 1BXK NAD 7.48503
470 5MGZ SAH 7.62712
471 4DMG SAM 7.63359
472 1OAA OAA 7.72201
473 1ORR NAD 7.78098
474 5WP4 SAH 7.78443
475 5DF1 NAP 7.78443
476 5DF1 58X 7.78443
477 3PT9 SAH 7.78443
478 2Q2V NAD 7.84314
479 4POO SAM 8
480 4TQG NDP 8.04954
481 6GKV SAH 8.08383
482 3X01 AMP 8.08383
483 1DMR PGD 8.08383
484 5FFF NAP 8.17121
485 5FFF 5XC 8.17121
486 3JWH SAH 8.29493
487 3SJ7 NDP 8.33333
488 5Y1G AKB 8.38323
489 5Y1G NAD 8.38323
490 3AD8 FAD 8.38323
491 3AD8 PYC 8.38323
492 1JQ3 AAT 8.44595
493 5LOG SAH 8.58369
494 4DCM SAM 8.68263
495 1NAA 6FA 8.68263
496 1NAA ABL 8.68263
497 2EJU SAH 8.73016
498 2RI1 GLP 8.93617
499 1SQF SAM 8.98204
500 5GM1 SAH 9.09091
501 3O03 NAP 9.27835
502 5FA8 SAM 9.31677
503 4LHD GLY 9.58084
504 3GEG NAD 9.7166
505 2DPM SAM 9.85915
506 1I1N SAH 10.177
507 4CVN ADP 10.4712
508 3P9C SAH 10.479
509 1Y8Q ATP 10.479
510 4OHU 2TK 10.7266
511 4OHU NAD 10.7266
512 5E1M SAH 10.7884
513 5E1M PRO PRO LYS ARG ILE ALA 10.7884
514 2F5Z FAD 10.9375
515 3GWZ SAH 11.0778
516 3GXO SAH 11.0778
517 6F7L FAD 11.0778
518 3Q87 SAM 11.2
519 1GPM AMP 11.3772
520 1DCP HBI 11.5385
521 3A25 SAM 11.6279
522 3NUG NAD 11.7409
523 1JG3 ADN 12.766
524 5A3B APR 12.8713
525 5OVK NDP 12.8906
526 5J60 FAD 13.125
527 2ZFU SAH 13.4884
528 1ZEM NAD 13.7405
529 2XRH NIO 14
530 1DL5 SAH 14.1956
531 4WH9 3M8 14.2077
532 1UZN NAP 14.5749
533 2HMT NAI 14.5833
534 1WZ1 DNS 15.0442
535 1V59 NAD 15.2695
536 4EUE NAI 15.5689
537 4NBT NAD 15.8333
538 3KO0 TFP 15.8416
539 2WSB NAD 16.9291
540 5W97 CHD 17.3913
541 5YEC ATP 20.1681
542 5E8J SAH 22.7273
543 1NNU TCT 31.6667
544 1NNU NAD 31.6667
545 4WG0 CHD 40
Pocket No.: 2; Query (leader) PDB : 1RJD; Ligand: SAM; Similar sites found with APoc: 135
This union binding pocket(no: 2) in the query (biounit: 1rjd.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 1GY8 NAD 1.49701
2 1RPN NDP 1.49701
3 1PN0 FAD 1.50376
4 1PN0 IPH 1.50376
5 3ZG6 APR 1.68919
6 3GDN FAD 1.79641
7 3GDN HBX 1.79641
8 2GN4 NDP 1.79641
9 3FPZ AHZ 1.84049
10 1D7O TCL 2.0202
11 1D7O NAD 2.0202
12 3HDY FDA 2.09581
13 3HDY FAD 2.09581
14 2IV2 MGD 2.09581
15 3S5W FAD 2.09581
16 2IV2 2MD 2.09581
17 6H3O FAD 2.09581
18 3O26 NDP 2.2508
19 1W6U NAP 2.31788
20 4REP FAD 2.39521
21 5J7X FAD 2.39521
22 5OCQ CIT 2.45614
23 2I7C AAT 2.4735
24 4KWI NAP 2.6616
25 4KWI 1TJ 2.6616
26 2IID FAD 2.69461
27 2IID PHE 2.69461
28 5TS5 FAD 2.69461
29 3NYC IAR 2.69461
30 3NYC FAD 2.69461
31 4LH7 1X8 2.78638
32 1ZK4 NAP 2.78884
33 4GKV NAD 2.97619
34 1BZL FAD 2.99401
35 1BZL GCG 2.99401
36 2WPF FAD 2.99401
37 2WPF WPF 2.99401
38 5LW0 AR6 3.0303
39 6HKE MLT 3.14465
40 5KVA SAM 3.23741
41 1OC2 NAD 3.29341
42 1OC2 TDX 3.29341
43 1COY FAD 3.29341
44 1COY AND 3.29341
45 1R6D DAU 3.29341
46 2GV8 FAD 3.29341
47 1SB8 UD2 3.29341
48 1SB8 NAD 3.29341
49 2GVC FAD 3.29341
50 3EYA FAD 3.29341
51 6HOY TSN 3.31126
52 6HOY AR6 3.31126
53 3OIG NAD 3.38346
54 3RNM FAD 3.44828
55 5HV7 RBL 3.59281
56 2VVL FAD 3.59281
57 3E8T UQ8 3.63636
58 4IRP UDP 3.89222
59 3LU1 NAD 3.89222
60 1W73 NAP 3.97351
61 1W8D NAP 3.97351
62 5TQZ GLC 4
63 4FC7 NAP 4.19162
64 4FC7 COA 4.19162
65 2YG3 FAD 4.19426
66 3GD4 FAD 4.30528
67 4DSG FAD 4.49102
68 4DSG UDP 4.49102
69 2AQJ FAD 4.49102
70 2AQJ TRP 4.49102
71 5WQP NCA 4.70085
72 5WQP NAP 4.70085
73 5ECP MET 4.79042
74 4D5G FAD 4.79042
75 4D5G TPP 4.79042
76 1ELI PYC 4.79042
77 5NA1 FAD 4.79042
78 5U8U FAD 5.08982
79 4ZRN UPG 5.12821
80 2X1L MET 5.15267
81 3H4V NAP 5.20833
82 3H4V DVP 5.20833
83 1U7T NAD 5.36398
84 3GF4 FAD 5.38922
85 3GF4 UPG 5.38922
86 2VZ0 D64 5.59701
87 2VZ0 NAP 5.59701
88 3ICT FAD 5.61225
89 3ICS FAD 5.61225
90 3ICR FAD 5.61225
91 4OYA 1VE 5.68862
92 1X87 NAD 5.98802
93 4J36 1HR 5.98802
94 3BJC WAN 5.98802
95 1SQS TLA 6.19835
96 1XHC FAD 6.58683
97 3AY6 BGC 6.69145
98 3AY6 NAI 6.69145
99 3G6N MET ALA SER 6.80628
100 1A27 NAP 6.92042
101 4O4Z N2O 7.14286
102 4USR FAD 7.18563
103 1EU1 MGD 8.08383
104 2ZXI FAD 8.08383
105 2GAG FAD 8.08383
106 2GAG FOA 8.08383
107 4X9M FAD 8.68263
108 2NU8 COA 8.68263
109 6CZ7 MGD 8.98204
110 5JCM FAD 9.28144
111 4AVV GHE 9.31373
112 4AVV CD 9.31373
113 5LAU AR6 9.61539
114 2HNK SAH 9.62343
115 3BY8 MLT 9.85915
116 1H0H MGD 9.88024
117 3AB4 LYS 10.1124
118 1ZK7 FAD 10.1796
119 2C7G ODP 10.1796
120 2C7G FAD 10.1796
121 1G8K MGD 10.479
122 5IJJ I6P 10.9375
123 5OVL NAP 11
124 1YQZ FAD 11.0778
125 5MIT NAP 11.9266
126 5MIT FAD 11.9266
127 2Q1W NAD 12.3123
128 5OJI NAP 12.6923
129 5OJI ISN 12.6923
130 2C31 TZD 12.8743
131 2C31 ADP 12.8743
132 1Z45 NAD 12.8743
133 5OOH NAP 13.1068
134 5OOH 9ZZ 13.1068
135 1V59 FAD 15.2695
Pocket No.: 3; Query (leader) PDB : 1RJD; Ligand: SAM; Similar sites found with APoc: 15
This union binding pocket(no: 3) in the query (biounit: 1rjd.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1QMG DMV 2.09581
2 5ZBR ANP 2.09581
3 3UWB BB2 2.5974
4 6MVU K4V 2.69461
5 4HSU FAD 3.59281
6 4FWE FAD 3.59281
7 5ECP JAA 4.79042
8 4DO1 ANN 4.79042
9 1H82 GZZ 5.68862
10 1H82 FAD 5.68862
11 5EW0 3C7 5.98291
12 3BPX SAL 6.08108
13 4JX1 CAH 7.9646
14 1JJV ATP 9.2233
15 5N53 8NB 11.6766
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