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Receptor
PDB id Resolution Class Description Source Keywords
1R00 2.5 Å EC: 1.-.-.- CRYSTAL STRUCTURE OF ACLACINOMYCIN-10-HYDROXYLASE (RDMB) IN WITH S-ADENOSYL-L-HOMOCYSTEINE (SAH) STREPTOMYCES PURPURASCENS ANTHRACYCLINE HYDROXYLASE METHYLTRANSFERASE POLYKETIDE STREPTOMYCES TAILORING ENZYME OXIDOREDUCTASE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF ACLACINOMYCIN-10-HYDROXYLASE, S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE INVOLVED IN ANTHRACYCLINE BIOSYNTHESIS IN STREPTOMY PURPURASCENS. J.MOL.BIOL. V. 334 269 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:421;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
SAH A:635;
Valid;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1QZZ 2.1 Å EC: 1.-.-.- CRYSTAL STRUCTURE OF ACLACINOMYCIN-10-HYDROXYLASE (RDMB) IN WITH S-ADENOSYL-L-METHIONINE (SAM) STREPTOMYCES PURPURASCENS ANTHRACYCLINE HYDROXYLASE METHYLTRANSFERASE POLYKETIDE STREPTOMYCES TAILORING ENZYMES STRUCTURAL PROTEOMICS IN ESPINE STRUCTURAL GENOMICS OXIDOREDUCTASE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF ACLACINOMYCIN-10-HYDROXYLASE, S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE INVOLVED IN ANTHRACYCLINE BIOSYNTHESIS IN STREPTOMY PURPURASCENS. J.MOL.BIOL. V. 334 269 2003
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 318 families.
1 1R00 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1QZZ - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 1R00 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1QZZ - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 1TW2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5EEH - P9P C6 H4 Cl N O3 c1cc(c(cc1....
3 5EEG - S8M C14 H20 N10 O3 S c1nc(c2c(n....
4 1TW3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 4WXH - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 3I53 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 1R00 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 1QZZ - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1QZZ; Ligand: SAM; Similar sites found with APoc: 542
This union binding pocket(no: 1) in the query (biounit: 1qzz.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 2XVF FAD 1.3369
2 4BLW AMP 1.38408
3 4BLW SAH 1.38408
4 1NJR XYL 1.40845
5 1ORR NAD 1.44092
6 2DTX BMA 1.51515
7 2YY7 NAD 1.60256
8 5YB7 ORN 1.60428
9 5YB7 FAD 1.60428
10 2ZWI C5P 1.60858
11 2UYQ SAM 1.6129
12 1RLZ NAD 1.62602
13 1WVG APR 1.67131
14 1SB8 UD2 1.70455
15 1SB8 NAD 1.70455
16 3I6I NDP 1.7341
17 5OJ7 AR6 1.74825
18 1RJD SAM 1.79641
19 4MDH NAD 1.79641
20 5MDH NAD 1.8018
21 3A27 SAM 1.83824
22 2EFJ SAH 1.87166
23 1T9D FAD 1.87166
24 5WKC FAD 1.87166
25 2ZXI FAD 1.87166
26 1VKO NAD 1.87166
27 2WPB ZZI 1.97368
28 1S7G APR 1.97628
29 6BQ6 TER 2.1148
30 6BWL NAD 2.13415
31 5JJR SAH 2.13904
32 3HDY FAD 2.13904
33 3EYA FAD 2.13904
34 3HDY FDA 2.13904
35 3HDY GDU 2.13904
36 5HSA FAS 2.13904
37 5OC1 FAD 2.13904
38 3KLJ FAD 2.13904
39 5BJX UDP 2.18579
40 5BJX NAD 2.18579
41 5BW4 SAM 2.24719
42 1YXM ADE 2.31023
43 6FA4 GNP 2.31214
44 1XHL NDP 2.3569
45 4ZA2 NAD 2.37154
46 4GKV NAD 2.38095
47 5HJM MTA 2.40642
48 1U2Z SAH 2.40642
49 5JAQ NAI 2.40642
50 1X87 NAD 2.40642
51 5MB4 NAG 2.40642
52 1H82 GZZ 2.40642
53 5EB4 FAD 2.40642
54 1H82 FAD 2.40642
55 3G5S FAD 2.40642
56 5KOX FAD 2.40642
57 5KOX RFP 2.40642
58 3S5W FAD 2.40642
59 2WME NAP 2.40642
60 5A1S FLC 2.40642
61 2WOX NDP 2.40642
62 3U31 NAD 2.41379
63 1T3D CYS 2.42215
64 4MO2 FAD 2.44565
65 4MO2 FDA 2.44565
66 5F7J ADE 2.5
67 2RH4 EMO 2.52708
68 1TZD ADP 2.54545
69 3VC1 GST 2.5641
70 3VC1 SAH 2.5641
71 3RIY NAD 2.5641
72 6F9Q NAD 2.57353
73 1OC2 TDX 2.58621
74 1OC2 NAD 2.58621
75 3QWI NAP 2.59259
76 3QWI CUE 2.59259
77 5EJ2 NAD 2.5974
78 3CL7 HYN 2.5974
79 2EXX NAP 2.61438
80 2P41 SAH 2.62295
81 3ELW SAM 2.66667
82 3ELW GP3 2.66667
83 5X62 SAH 2.6738
84 6C8R EQV 2.6738
85 6C8R SAH 2.6738
86 2IVD FAD 2.6738
87 2EJU SAH 2.6738
88 4D5G TPP 2.6738
89 4D5G FAD 2.6738
90 3OND NAD 2.6738
91 3OND ADN 2.6738
92 4UP4 GAL NAG 2.6738
93 4CNK FAD 2.6738
94 2VHW NAI 2.6738
95 2YX1 SFG 2.67857
96 3BGD SAH 2.69231
97 3BGD PM6 2.69231
98 3SJ7 NDP 2.77778
99 2CFC NAD 2.8
100 1BXK NAD 2.8169
101 5GWX SAR 2.8169
102 5GWX SAM 2.8169
103 3GCZ SAM 2.83688
104 4BUZ NAD 2.84553
105 4BUZ OCZ 2.84553
106 4BUZ OAD 2.84553
107 3LCV SAM 2.84698
108 3EVG SAH 2.90909
109 5O42 9JW 2.91971
110 5O42 NAD 2.91971
111 5O42 BGC 2.91971
112 3VSE SAH 2.94118
113 4RSL FAD 2.94118
114 3GDN FAD 2.94118
115 3GDN HBX 2.94118
116 4UCI SAM 2.94118
117 4U7W NDP 2.94118
118 2XVE FAD 2.94118
119 2QA1 FAD 2.94118
120 1V59 NAD 2.94118
121 4HXY NDP 2.96804
122 5CUQ NSC 2.99625
123 4POO SAM 3
124 1Z3C SA8 3.02013
125 1H2B NAJ 3.06407
126 4PIO SAH 3.09598
127 4PIO AVI 3.09598
128 4A59 AMP 3.10966
129 5ZW3 SAH 3.11111
130 5E72 SAM 3.17919
131 4UP3 FAD 3.18471
132 4PTN GXV 3.207
133 5DNK SAH 3.20856
134 3NDJ JHZ 3.20856
135 3NDJ SAH 3.20856
136 6B3A SAM 3.20856
137 1ELI PYC 3.20856
138 1I2B USQ 3.20856
139 1I2B NAD 3.20856
140 1I2B UPG 3.20856
141 4LHD GLY 3.20856
142 1Q9I FAD 3.20856
143 1Q9I TEO 3.20856
144 2VVM FAD 3.20856
145 2JHP SAH 3.20856
146 2VVL FAD 3.20856
147 4AT0 FAD 3.20856
148 4MIG G3F 3.20856
149 2Q0L FAD 3.21543
150 2EG5 SAH 3.22581
151 1RJW ETF 3.24484
152 3EVF GTA 3.2491
153 3EVF SAH 3.2491
154 1UDB UFG 3.25444
155 1UDB NAD 3.25444
156 5DOZ NDP 3.25444
157 1WUU GLA 3.25815
158 3LCC SAH 3.40426
159 3PFG SAM 3.42205
160 3PFG TLO 3.42205
161 4RVG SAM 3.47594
162 4RVG TYD 3.47594
163 4RPL FAD 3.47594
164 4RPL 3UC 3.47594
165 1BZL GCG 3.47594
166 1BZL FAD 3.47594
167 3GF4 FAD 3.47594
168 2Y6Q I7T 3.47594
169 1TPY SAH 3.48432
170 1KPH SAH 3.48432
171 1KPG SAH 3.48432
172 5FTW SAH 3.51562
173 2XVM SAH 3.51759
174 3GU3 SAH 3.52113
175 3MB5 SAM 3.52941
176 1I8T FAD 3.54223
177 2WSB NAD 3.54331
178 3ITJ CIT 3.5503
179 3FRH SAH 3.55731
180 3ZV6 NAD 3.55872
181 3ZV6 4HB 3.55872
182 4G5H UD7 3.58127
183 4G5H NAP 3.58127
184 6HOY TSN 3.64238
185 6HOY AR6 3.64238
186 1QAN SAH 3.68852
187 3GRU AMP 3.72881
188 3L9W AMP 3.74332
189 4AZW SAM 3.74332
190 3S1S SAH 3.74332
191 3L9W GSH 3.74332
192 5WGR FAD 3.74332
193 2BRY FAD 3.74332
194 5U8U FAD 3.74332
195 4JDR FAD 3.74332
196 3ABI NAD 3.74332
197 3KIF GDL 3.77358
198 5KOK S9T 3.77834
199 5KOK R9T 3.77834
200 5KOK SAH 3.77834
201 4M37 SAH 3.79009
202 1G55 SAH 3.79009
203 4M38 SAH 3.79009
204 1LLU NAD 3.80117
205 5W7M SAH 3.84615
206 2BZG SAH 3.87931
207 2Q1W NAD 3.9039
208 1W6F ISZ 3.95683
209 1ZK4 NAP 3.98406
210 1ZK4 AC0 3.98406
211 2JB2 PHE 4.01069
212 2JB2 FAD 4.01069
213 1GY8 NAD 4.01069
214 1U1I NAD 4.01069
215 6F97 FAD 4.01069
216 4DCM SAM 4.01069
217 2ZIF SAM 4.0404
218 6B92 SAH 4.08163
219 1R6D DAU 4.1543
220 1R6D NAD 4.1543
221 4USQ FAD 4.15512
222 3DMH GMP 4.19948
223 3DMH SAM 4.19948
224 1E3W NAD 4.21456
225 1E6W NAD 4.23077
226 4CS9 AMP 4.2328
227 1Q0S SAH 4.2471
228 5BVA FAD 4.27807
229 2NVK FAD 4.27807
230 4YNU FAD 4.27807
231 4YNU LGC 4.27807
232 2YG3 FAD 4.27807
233 3LKZ SFG 4.36137
234 3O7W SAM 4.42177
235 4ZRN NAD 4.48718
236 4ZRN UPG 4.48718
237 2PZM UDP 4.54545
238 2PZM NAD 4.54545
239 1YBH FAD 4.54545
240 1V5F TPP 4.54545
241 1V5F FAD 4.54545
242 3E1T FAD 4.54545
243 1E3I CXF 4.54545
244 4C3Y FAD 4.54545
245 4C3Y ANB 4.54545
246 4CQM NAP 4.5977
247 2GN4 NDP 4.65116
248 2GN4 UD1 4.65116
249 3OID NDP 4.65116
250 1XCL SAH 4.68085
251 1DUG GSH 4.70085
252 6GFK SAH 4.78088
253 3O03 NAP 4.811
254 1UWK URO 4.81283
255 1UWK NAD 4.81283
256 1EU1 MGD 4.81283
257 4DMG SAM 4.81283
258 3NUG NAD 4.8583
259 2HMT NAI 4.86111
260 5DM1 5D7 4.86891
261 5DM1 SAH 4.86891
262 3P2E SAH 4.88889
263 5MIT NAP 4.89297
264 5MIT FAD 4.89297
265 5Z2L NDP 4.89796
266 2Q7V FAD 4.92308
267 2DSA HPX 4.92611
268 2FR1 NDP 4.93827
269 2A14 SAH 4.94297
270 1U7T TDT 4.98084
271 3PT9 SAH 5.08021
272 1YY5 FAD 5.08021
273 1RSG FAD 5.08021
274 5BRT FAD 5.08021
275 5BRT CH9 5.08021
276 4ZNO SUC 5.08021
277 3OFK SAH 5.09259
278 2PXX SAH 5.11628
279 5ULP KB1 5.22388
280 5YJI SAH 5.28169
281 5YJI 8WO 5.28169
282 4NTO 1PW 5.31401
283 4L2I FAD 5.32319
284 2BD0 NAP 5.32787
285 1PR9 NAP 5.32787
286 3D3W NAP 5.32787
287 6D6Y SAH 5.34759
288 4KGD FAD 5.34759
289 4KGD TDP 5.34759
290 5ZYN FAD 5.34759
291 1H0H MGD 5.34759
292 2AE2 NAP 5.38462
293 2AE2 PTO 5.38462
294 5OJI ISN 5.38462
295 5OJI NAP 5.38462
296 5XNC MTA 5.39084
297 5W7K SAH 5.44872
298 3DXY SAM 5.50459
299 3MQ2 SAH 5.50459
300 2OD9 A1R NCA 5.51948
301 2QQF A1R 5.51948
302 1P1C SAH 5.52764
303 3JWH SAH 5.52995
304 2ZFU SAH 5.5814
305 2VT3 ATP 5.5814
306 1XXR MAN 5.59006
307 1RKX NAD 5.60224
308 5T67 SAH 5.61497
309 5T67 JHZ 5.61497
310 2ZWA SAH 5.61497
311 3K7M FAD 5.61497
312 3RNM FAD 5.61497
313 3A25 SAM 5.64784
314 5M58 SAH 5.65217
315 6FDF SAH 5.68862
316 1I1N SAH 5.75221
317 3TKA SAM 5.76369
318 1WY7 SAH 5.7971
319 1KEW NAD 5.81717
320 1REO FAD 5.88235
321 5TS5 FAD 5.88235
322 5KMS FAD 5.88235
323 4EA7 COA 5.90909
324 4EA7 JB2 5.90909
325 4QTU SAM 5.92593
326 1G0N NDP 6.00707
327 1G0N PHH 6.00707
328 1XSE NDP 6.1017
329 5FWA J7C 6.14973
330 1COY AND 6.14973
331 1JQD HSM 6.16438
332 1JQD SAH 6.16438
333 2AOT SAH 6.16438
334 3A4T SFG 6.20438
335 5FUB SAH 6.23145
336 4YMH SAH 6.25
337 1EFV FAD 6.27451
338 1EFV AMP 6.27451
339 5YRL GLC GLC 6.33803
340 5YRF GLC GLC 6.33803
341 5DLY SAH 6.39098
342 5DLY 5D7 6.39098
343 3QOX SAH 6.41711
344 4KRG SAH 6.41711
345 3SSO SAH 6.41711
346 2VDV SAM 6.50407
347 3WDM ADN 6.51341
348 5E5U MLT 6.53266
349 2FK8 SAM 6.60377
350 3FUU ADN 6.64207
351 1TUU AMP 6.68449
352 1SZD APR 6.73401
353 4LWP SAH 6.79348
354 1SQF SAM 6.95187
355 2IID PHE 6.95187
356 2IID FAD 6.95187
357 4XQC NAD 6.95187
358 1WG8 SAM 7.01754
359 2NXE SAM 7.08661
360 2WK1 SAH 7.0922
361 2Q46 NAP 7.11462
362 1VL8 NAP 7.11611
363 5UFN SAH 7.14286
364 1LSS NAD 7.14286
365 5MW4 5JU 7.18563
366 1D4D FAD 7.21925
367 5JE0 AZ8 7.28745
368 5JE0 SAH 7.28745
369 1AE1 NAP 7.32601
370 5LW0 AR6 7.35931
371 6GKV SAH 7.40741
372 3LU1 NAD 7.41758
373 5YF1 SFG 7.45856
374 5YF1 8V0 7.45856
375 5ERG SAM 7.48663
376 4C4A SAH 7.48663
377 1Y8Q ATP 7.48663
378 1R37 NAD 7.4928
379 4CNO 9PY 7.53968
380 1WEI ADE 7.55556
381 1PN0 FAD 7.75401
382 1PN0 IPH 7.75401
383 3TLJ SAH 7.7748
384 1XKQ NDP 7.85714
385 5F2K OCA 7.88043
386 5F2K SAH 7.88043
387 3H2B SAH 7.88177
388 1N2X SAM 7.97342
389 5BSZ SAH 8
390 1FEC FAD 8.02139
391 1QO8 FAD 8.02139
392 3FPF TNA 8.05369
393 3FPF MTA 8.05369
394 1C0I BE2 8.28877
395 1C0I FAD 8.28877
396 2OBF SAH 8.3045
397 2OBF F83 8.3045
398 1L1E SAH 8.36237
399 5O4J 9KH 8.39416
400 5O4J SAH 8.39416
401 1F3L SAH 8.41121
402 2DT5 NAD 8.53081
403 3X0D SAH 8.55615
404 1FK8 NAD 8.56031
405 1I9G SAM 8.57143
406 3HVJ 705 8.59729
407 4W6Z 8ID 8.64553
408 5LAU AR6 8.65385
409 4NEC SAH 8.71212
410 5FA5 MTA 8.71935
411 2HQM FAD 8.76827
412 1G60 SAM 8.84615
413 5MGZ SAH 8.8983
414 3FZG SAM 9
415 6FP4 FAD 9.09091
416 1ZQ9 SAM 9.12281
417 4X60 3XV 9.14286
418 4X60 SFG 9.14286
419 2DPM SAM 9.15493
420 4GQB 0XU 9.30233
421 4N49 SAM 9.34579
422 5UAO FAD 9.35829
423 2CIG 1DG 9.43396
424 3RKR NAP 9.54198
425 5JGL SAM 9.68858
426 5F8F SFG 9.81432
427 2PX8 SAH 10.0372
428 5NC1 NAG 10.1266
429 5N0J FAD 10.1604
430 5XLX SAH 10.2837
431 2GUD MAN 10.6557
432 2NUO BGC 10.6557
433 2GUC MAN 10.6557
434 2HYR BGC GLC 10.6557
435 2GUD BMA 10.6557
436 2NU5 NAG 10.6557
437 2HYQ MAN MAN 10.6557
438 2WA2 SAM 10.8696
439 4URF NAD 10.8871
440 1ZEM NAD 11.0687
441 6DUB SAH 11.2613
442 1NV8 SAM 11.2676
443 1NV8 MEQ 11.2676
444 3G2O SAM 11.3712
445 4TQG NDP 11.4551
446 2PT9 S4M 11.5265
447 2PT9 2MH 11.5265
448 1EJ0 SAM 11.6667
449 1DL5 SAH 11.6719
450 1JQ3 AAT 11.8243
451 2O07 SPD 11.8421
452 2O07 MTA 11.8421
453 3QFA FAD 12.069
454 5MPT SAH 12.2995
455 2F5Z FAD 12.5
456 1RPN NDP 12.5373
457 6CI9 NAP 12.7413
458 2PWY SAH 12.7907
459 5WP5 SAH 12.8342
460 4YUW 4JU 13.1579
461 4YUW S4M 13.1579
462 6FLZ MMA 13.1944
463 3G89 SAM 13.253
464 4XUC 43G 13.3028
465 4XUC SAM 13.3028
466 6ARJ BW4 13.467
467 6ARJ SAH 13.467
468 5DX0 SFG 13.467
469 5DWQ SFG 13.467
470 5DX1 SFG 13.467
471 5DX8 SFG 13.467
472 5DXA SFG 13.467
473 3EGI ADP 13.5922
474 4EUE NAI 13.6364
475 1BC5 SAH 13.7546
476 2I7C AAT 13.7809
477 5E9W SAH 13.7821
478 3T7S SAM 13.806
479 5WP4 SAH 13.9037
480 4II2 ATP 13.9037
481 1PNO NAP 15
482 3IHG FAD 15.508
483 4RIF 3R2 15.8311
484 4FZV SAM 15.8996
485 5E8J SAH 15.9091
486 5W7R SAH 16.0428
487 5W7R 9Z7 16.0428
488 4KIB SAH 16.2465
489 6ECU SAH 16.4557
490 5THY SAH 16.7901
491 5THZ SAH 16.7901
492 6ECW SAH 16.8254
493 4PNE SAH 17.2185
494 1XTP SAI 17.3228
495 6ECT SAM 17.4455
496 3BXO SAM 17.5732
497 5U19 SAH 17.5953
498 5U19 827 17.5953
499 1VE3 SAM 17.6211
500 4M73 M72 17.8042
501 4M73 SAH 17.8042
502 6F5Z SAH 18.1818
503 5GM1 SAH 18.5185
504 4Y30 49L 18.5185
505 4Y30 SAH 18.5185
506 4ONQ SFG 18.7675
507 4IWN GEK 18.7773
508 1IM8 SAI 18.8525
509 4OBW SAM 19.0661
510 3Q87 SAM 19.2
511 4KRI SAH 19.2513
512 3OU2 SAH 19.7248
513 4R6W PC 20.155
514 4R6W SAH 20.155
515 1R18 SAH 20.7048
516 3GDH SAH 21.1618
517 3C6K SPD 21.2598
518 3C6K MTA 21.2598
519 5E1M SAH 21.5768
520 5E1M PRO PRO LYS ARG ILE ALA 21.5768
521 5ICE 2H4 21.5909
522 5ICE SAH 21.5909
523 5LOG SAH 22.3176
524 5YJF SAH 22.8873
525 5YJF 8WO 22.8873
526 1L3I SAH 23.4375
527 3P9C SAH 25.2747
528 1KYZ SAH 26.4706
529 1KYZ FER 26.4706
530 3TKY SAH 26.6304
531 1JG3 ADN 27.234
532 4A6D SAM 28.8952
533 5FA8 SAM 31.0559
534 4E70 N7I 36.3636
535 1FP1 SAH 36.631
536 3GWZ SAH 37.1274
537 3GXO SAH 37.1274
538 1FP2 SAH 38.3523
539 1FP2 HMO 38.3523
540 1ZGA SAH 41.1765
541 3LST SAH 42.8161
542 6C5B SAH 45.1613
Pocket No.: 2; Query (leader) PDB : 1QZZ; Ligand: SAM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1qzz.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1QZZ; Ligand: SAM; Similar sites found with APoc: 2
This union binding pocket(no: 3) in the query (biounit: 1qzz.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 5HCF BGC 5.53506
2 1ZX5 LFR 12.3333
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