Receptor
PDB id Resolution Class Description Source Keywords
1QJB 2 Å EC: 2.7.11.1 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 1) HOMO SAPIENS KINASE INHIBITOR-PEPTIDE COMPLEX SIGNAL TRANSDUCTION
Ref.: STRUCTURAL ANALYSIS OF 14-3-3 PHOSPHOPEPTIDE COMPLE IDENTIFIES A DUAL ROLE FOR THE NUCLEAR EXPORT SIGNA 14-3-3 IN LIGAND BINDING MOL.CELL V. 4 153 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ALA ARG SER HIS SEP TYR PRO ALA Q:3;
S:4;
 Valid;
Valid;
 none;
none;
 Ki = 416 nM
951.933 n/a P(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4N84 2.5 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF 14-3-3ZETA IN COMPLEX WITH A 12-CARBON- CYCLIC PEPTIDE DERIVED FROM EXOS HOMO SAPIENS 14-3-3 ADAPTOR PROTEIN PROTEIN-PROTEIN INTERACTION CROSS-SIGNALING PROTEIN
Ref.: CONSTRAINED PEPTIDES WITH TARGET-ADAPTED CROSS-LINK INHIBITORS OF A PATHOGENIC PROTEIN-PROTEIN INTERACT ANGEW.CHEM.INT.ED.ENGL. V. 53 2489 2014
Members (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 133 families.
1 1QJB Ki = 416 nM ALA ARG SER HIS SEP TYR PRO ALA n/a n/a
2 6FNA - DWE C50 H66 N6 O20 P2 c1ccc(c(c1....
3 4N84 Kd = 41 nM GLY MKD LEU ASP MKD LEU ASP LEU ALA SER n/a n/a
4 1QJA Kd = 416 nM ARG LEU TYR HIS SEP LEU PRO ALA n/a n/a
5 6FNC - DWK C40 H48 N4 O15 P2 c1ccc(c(c1....
6 6FN9 ic50 = 284 uM DW8 C27 H38 N3 O10 P CCCNC(=O)C....
7 2C1N - ALA ARG LYS SEP THR GLY GLY LYS n/a n/a
8 2V7D Kd = 261 nM LYS SER ALA TPO THR THR VAL MET ASN PRO n/a n/a
9 6FNB - DWQ C59 H84 N6 O22 P2 c1ccc(c(c1....
10 3NKX Kd = 7.5 uM GLN ARG SER THR SEP THR PRO ASN VAL HIS n/a n/a
70% Homology Family (79)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 101 families.
1 6Y3W - LYS ARG ARG ARG LYS SEP CYS GLN ALA NH2 O85 n/a n/a
2 6HKB - ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
3 6FI5 Kd = 3 uM THR PRO SEP LEU PRO DAL 60H n/a n/a
4 5BTV Kd = 140 uM GLY SEP LEU GLY n/a n/a
5 6W0L - ALA ARG VAL SER MET ARG ARG MET SEP ASN n/a n/a
6 6XWD Kd = 2.18 uM ASN LYS ASN ALA ASN SEP SER PRO VAL n/a n/a
7 4Y32 ic50 = 90.1 uM ARG THR PRO SEP LEU PRO THR 49F n/a n/a
8 4Y5I ic50 = 301.3 uM ACE ARG THR PRO SEP LEU PRO THR PIP n/a n/a
9 6FBB - SER ARG SEP SER PRO n/a n/a
10 5N5W - 8OE C11 H8 Cl2 N2 O c1cc(ccc1N....
11 6FBY Kd = 9.3 uM ACE ARG THR PRO SEP LEU PRO GLY D4H n/a n/a
12 6Y3M - GLN SER TYR TPO VAL n/a n/a
13 6HHP Kd = 32 nM ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
14 4DHS - Y03 C14 H12 Cl2 N O5 P c1ccc(c(c1....
15 6Y3S - ASN ALA ARG SER ALA SEP PHE SER GLN GLY n/a n/a
16 6GHP - ACE LYS ARG ARG LYS SEP VAL n/a n/a
17 4DHO - Y09 C15 H16 N O6 P COc1cccc(c....
18 6Y8A - ARG SER LEU SEP ALA PRO GLY ASN n/a n/a
19 6Y8E - ARG SER PHE SEP GLU PRO PHE GLY n/a n/a
20 3IQV Kd = 6.6 uM FSC C36 H56 O12 C[C@@H]1[C....
21 4IEA Kd = 346 nM ARG SER ALA SEP GLU PRO SER LEU n/a n/a
22 6HN2 - ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
23 6Y58 Kd = 15.8 uM VAL TYR ARG SER LEU SEP PHE GLU n/a n/a
24 6FAW Kd = 2.7 uM ACE ARG THR PRO SEP LEU PRO GLY D3K n/a n/a
25 5N75 - ARG SER HIS SEP SER PRO ALA SER LEU GLN n/a n/a
26 4DHN - 0KC C13 H18 N O5 P c1ccc(c(c1....
27 3MHR - ARG ALA HIS SEP SER PRO ALA SER LEU GLN n/a n/a
28 4DHP - Y07 C15 H12 Cl F3 N O5 P c1ccc(c(c1....
29 3LW1 Kd = 16.3 uM PHE LYS TPO GLU GLY PRO ASP SER ASP n/a n/a
30 3SP5 Kd = 0.56 uM LYS ARG ARG LYS SEP VAL n/a n/a
31 4DHU - 0KH C14 H12 Cl2 N O5 P c1ccc(c(c1....
32 6HMT Kd = 92 nM ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
33 6Y1D - LYS ARG ARG ARG LYS SEP CYS GLN ALA NH2 n/a n/a
34 6XY5 - LYS ARG ARG ARG LYS SEP CYS GLN ALA O4E n/a n/a
35 3O8I - M1T C7 H14 O4 COCC(=O)CC....
36 6Y18 - LYS ARG ARG ARG LYS SEP CYS GLN ALA O68 n/a n/a
37 6TJM - NE5 C24 H16 N2 O8 c1ccc(cc1)....
38 5OEH - 9SZ C42 H32 O8 P2 c1ccc2c(c1....
39 4DHT - 0KG C14 H20 N O5 P c1ccc(c(c1....
40 6HKF - ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
41 6Y3O - ARG LYS LEU SEP LEU GLN GLU ARG n/a n/a
42 6Y8D - VAL GLU HIS SEP LEU ASP ASN LYS n/a n/a
43 5LU1 - ARG ARG ALA SEP ALA PRO LEU PRO n/a n/a
44 3IQJ Kd = 7.5 uM GLN ARG SER THR SEP THR PRO ASN VAL HIS n/a n/a
45 4FR3 Kd = 0.07 uM 0V4 C27 H44 O8 C[C@@H]1[C....
46 5HF3 Kd = 13.4 uM ACE ARG THR PRO SEP LEU PRO THR 60H n/a n/a
47 5N5R - NV1 C13 H20 N2 O Cc1cccc(c1....
48 4DHM - 0KB C15 H13 F3 N O5 P c1ccc(c(c1....
49 4DAT - SER SER PHE TYR PRO SEP ALA GLU GLY n/a n/a
50 6Y8B - TYR ASP LEU SEP LEU PRO PHE PRO n/a n/a
51 6FI4 Kd = 2.2 uM PRO SEP LEU PRO DVA 60H n/a n/a
52 3IQU - GLN ARG SER THR SEP THR n/a n/a
53 4DHQ - Y06 C14 H13 Cl N O5 P c1ccc(c(c1....
54 4DHR - Y04 C14 H13 Cl N O5 P c1ccc(c(c1....
55 4Y3B ic50 = 90.1 uM 49F C7 H15 N O COCC[C@@H]....
56 5N5T - SER HIS SEP SER PRO ALA SER LEU n/a n/a
57 6HMU - ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
58 6XXC - LYS ARG ARG ARG LYS SEP CYS GLN ALA O3W n/a n/a
59 6FBW Kd = 16.5 uM ARG THR PRO SEP LEU PRO GLY D4K n/a n/a
60 6FAV Kd = 4.7 uM ACE ARG THR PRO SEP LEU PRO GLY D3Q n/a n/a
61 5MXO - FSC C36 H56 O12 C[C@@H]1[C....
62 6TL3 - NJW C24 H17 N3 O7 c1ccc(cc1)....
63 6FAU Kd = 3.6 uM ACE ARG THR PRO SEP LEU PRO GLY D3W n/a n/a
64 1QJB Ki = 416 nM ALA ARG SER HIS SEP TYR PRO ALA n/a n/a
65 6FNA - DWE C50 H66 N6 O20 P2 c1ccc(c(c1....
66 4N84 Kd = 41 nM GLY MKD LEU ASP MKD LEU ASP LEU ALA SER n/a n/a
67 1QJA Kd = 416 nM ARG LEU TYR HIS SEP LEU PRO ALA n/a n/a
68 6FNC - DWK C40 H48 N4 O15 P2 c1ccc(c(c1....
69 6FN9 ic50 = 284 uM DW8 C27 H38 N3 O10 P CCCNC(=O)C....
70 2C1N - ALA ARG LYS SEP THR GLY GLY LYS n/a n/a
71 2V7D Kd = 261 nM LYS SER ALA TPO THR THR VAL MET ASN PRO n/a n/a
72 6FNB - DWQ C59 H84 N6 O22 P2 c1ccc(c(c1....
73 3NKX Kd = 7.5 uM GLN ARG SER THR SEP THR PRO ASN VAL HIS n/a n/a
74 2BR9 - ARG ARG GLN ARG SEP ALA PRO n/a n/a
75 2C63 - ARG ALA ILE SEP LEU PRO n/a n/a
76 5NWI Kd = 0.69 uM TYR PHE SER SEP ASN n/a n/a
77 1O9D Kd = 2.5 uM GLN SER TYR TPO VAL n/a n/a
78 5NWJ - HIS LEU TYR PHE SER SEP ASN n/a n/a
79 3E6Y Kd = 2.5 uM CW1 C34 H52 O12 C[C@@H]1[C....
50% Homology Family (79)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 70 families.
1 6Y3W - LYS ARG ARG ARG LYS SEP CYS GLN ALA NH2 O85 n/a n/a
2 6HKB - ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
3 6FI5 Kd = 3 uM THR PRO SEP LEU PRO DAL 60H n/a n/a
4 5BTV Kd = 140 uM GLY SEP LEU GLY n/a n/a
5 6W0L - ALA ARG VAL SER MET ARG ARG MET SEP ASN n/a n/a
6 6XWD Kd = 2.18 uM ASN LYS ASN ALA ASN SEP SER PRO VAL n/a n/a
7 4Y32 ic50 = 90.1 uM ARG THR PRO SEP LEU PRO THR 49F n/a n/a
8 4Y5I ic50 = 301.3 uM ACE ARG THR PRO SEP LEU PRO THR PIP n/a n/a
9 6FBB - SER ARG SEP SER PRO n/a n/a
10 5N5W - 8OE C11 H8 Cl2 N2 O c1cc(ccc1N....
11 6FBY Kd = 9.3 uM ACE ARG THR PRO SEP LEU PRO GLY D4H n/a n/a
12 6Y3M - GLN SER TYR TPO VAL n/a n/a
13 6HHP Kd = 32 nM ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
14 4DHS - Y03 C14 H12 Cl2 N O5 P c1ccc(c(c1....
15 6Y3S - ASN ALA ARG SER ALA SEP PHE SER GLN GLY n/a n/a
16 6GHP - ACE LYS ARG ARG LYS SEP VAL n/a n/a
17 4DHO - Y09 C15 H16 N O6 P COc1cccc(c....
18 6Y8A - ARG SER LEU SEP ALA PRO GLY ASN n/a n/a
19 6Y8E - ARG SER PHE SEP GLU PRO PHE GLY n/a n/a
20 3IQV Kd = 6.6 uM FSC C36 H56 O12 C[C@@H]1[C....
21 4IEA Kd = 346 nM ARG SER ALA SEP GLU PRO SER LEU n/a n/a
22 6HN2 - ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
23 6Y58 Kd = 15.8 uM VAL TYR ARG SER LEU SEP PHE GLU n/a n/a
24 6FAW Kd = 2.7 uM ACE ARG THR PRO SEP LEU PRO GLY D3K n/a n/a
25 5N75 - ARG SER HIS SEP SER PRO ALA SER LEU GLN n/a n/a
26 4DHN - 0KC C13 H18 N O5 P c1ccc(c(c1....
27 3MHR - ARG ALA HIS SEP SER PRO ALA SER LEU GLN n/a n/a
28 4DHP - Y07 C15 H12 Cl F3 N O5 P c1ccc(c(c1....
29 3LW1 Kd = 16.3 uM PHE LYS TPO GLU GLY PRO ASP SER ASP n/a n/a
30 3SP5 Kd = 0.56 uM LYS ARG ARG LYS SEP VAL n/a n/a
31 4DHU - 0KH C14 H12 Cl2 N O5 P c1ccc(c(c1....
32 6HMT Kd = 92 nM ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
33 6Y1D - LYS ARG ARG ARG LYS SEP CYS GLN ALA NH2 n/a n/a
34 6XY5 - LYS ARG ARG ARG LYS SEP CYS GLN ALA O4E n/a n/a
35 3O8I - M1T C7 H14 O4 COCC(=O)CC....
36 6Y18 - LYS ARG ARG ARG LYS SEP CYS GLN ALA O68 n/a n/a
37 6TJM - NE5 C24 H16 N2 O8 c1ccc(cc1)....
38 5OEH - 9SZ C42 H32 O8 P2 c1ccc2c(c1....
39 4DHT - 0KG C14 H20 N O5 P c1ccc(c(c1....
40 6HKF - ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
41 6Y3O - ARG LYS LEU SEP LEU GLN GLU ARG n/a n/a
42 6Y8D - VAL GLU HIS SEP LEU ASP ASN LYS n/a n/a
43 5LU1 - ARG ARG ALA SEP ALA PRO LEU PRO n/a n/a
44 3IQJ Kd = 7.5 uM GLN ARG SER THR SEP THR PRO ASN VAL HIS n/a n/a
45 4FR3 Kd = 0.07 uM 0V4 C27 H44 O8 C[C@@H]1[C....
46 5HF3 Kd = 13.4 uM ACE ARG THR PRO SEP LEU PRO THR 60H n/a n/a
47 5N5R - NV1 C13 H20 N2 O Cc1cccc(c1....
48 4DHM - 0KB C15 H13 F3 N O5 P c1ccc(c(c1....
49 4DAT - SER SER PHE TYR PRO SEP ALA GLU GLY n/a n/a
50 6Y8B - TYR ASP LEU SEP LEU PRO PHE PRO n/a n/a
51 6FI4 Kd = 2.2 uM PRO SEP LEU PRO DVA 60H n/a n/a
52 3IQU - GLN ARG SER THR SEP THR n/a n/a
53 4DHQ - Y06 C14 H13 Cl N O5 P c1ccc(c(c1....
54 4DHR - Y04 C14 H13 Cl N O5 P c1ccc(c(c1....
55 4Y3B ic50 = 90.1 uM 49F C7 H15 N O COCC[C@@H]....
56 5N5T - SER HIS SEP SER PRO ALA SER LEU n/a n/a
57 6HMU - ALA GLU GLY PHE PRO ALA TPO VAL n/a n/a
58 6XXC - LYS ARG ARG ARG LYS SEP CYS GLN ALA O3W n/a n/a
59 6FBW Kd = 16.5 uM ARG THR PRO SEP LEU PRO GLY D4K n/a n/a
60 6FAV Kd = 4.7 uM ACE ARG THR PRO SEP LEU PRO GLY D3Q n/a n/a
61 5MXO - FSC C36 H56 O12 C[C@@H]1[C....
62 6TL3 - NJW C24 H17 N3 O7 c1ccc(cc1)....
63 6FAU Kd = 3.6 uM ACE ARG THR PRO SEP LEU PRO GLY D3W n/a n/a
64 1QJB Ki = 416 nM ALA ARG SER HIS SEP TYR PRO ALA n/a n/a
65 6FNA - DWE C50 H66 N6 O20 P2 c1ccc(c(c1....
66 4N84 Kd = 41 nM GLY MKD LEU ASP MKD LEU ASP LEU ALA SER n/a n/a
67 1QJA Kd = 416 nM ARG LEU TYR HIS SEP LEU PRO ALA n/a n/a
68 6FNC - DWK C40 H48 N4 O15 P2 c1ccc(c(c1....
69 6FN9 ic50 = 284 uM DW8 C27 H38 N3 O10 P CCCNC(=O)C....
70 2C1N - ALA ARG LYS SEP THR GLY GLY LYS n/a n/a
71 2V7D Kd = 261 nM LYS SER ALA TPO THR THR VAL MET ASN PRO n/a n/a
72 6FNB - DWQ C59 H84 N6 O22 P2 c1ccc(c(c1....
73 3NKX Kd = 7.5 uM GLN ARG SER THR SEP THR PRO ASN VAL HIS n/a n/a
74 2BR9 - ARG ARG GLN ARG SEP ALA PRO n/a n/a
75 2C63 - ARG ALA ILE SEP LEU PRO n/a n/a
76 5NWI Kd = 0.69 uM TYR PHE SER SEP ASN n/a n/a
77 1O9D Kd = 2.5 uM GLN SER TYR TPO VAL n/a n/a
78 5NWJ - HIS LEU TYR PHE SER SEP ASN n/a n/a
79 3E6Y Kd = 2.5 uM CW1 C34 H52 O12 C[C@@H]1[C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ALA ARG SER HIS SEP TYR PRO ALA; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 ALA ARG SER HIS SEP TYR PRO ALA 1 1
2 ARG LEU TYR HIS SEP LEU PRO ALA 0.730263 0.961538
3 ARG SER HIS SEP SER PRO ALA SER LEU GLN 0.607143 0.898734
4 TYR HIS SEP VAL VAL ARG TYR ALA 0.579618 0.871795
5 ARG ALA HIS SEP SER PRO ALA SER LEU GLN 0.550633 0.848101
6 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.538462 0.860759
7 SER HIS SEP SER PRO ALA SER LEU GLN 0.535714 0.848101
8 LYS ARG ARG ARG HIS PRO SER GLY 0.535032 0.818182
9 LYS ARG ARG ARG HIS PRO SER 0.529032 0.802632
10 SER HIS SEP SER PRO ALA SER LEU 0.52795 0.858974
11 SER ARG ASP HIS SER ARG THR PRO MET 0.523256 0.795181
12 ALA TRP ARG HIS PRO GLN PHE GLY GLY 0.522222 0.75
13 SER SER TYR ARG ARG PRO VAL GLY ILE 0.518072 0.8375
14 HIS HIS ALA SER PRO ARG LYS 0.509091 0.828947
15 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.491124 0.8375
16 TYR TYR SER ILE ALA PRO HIS SER ILE 0.488095 0.8125
17 ALA LEU PRO HIS ALA ILE LEU ARG LEU 0.479532 0.7375
18 ARG SEP PRO VAL PHE SER 0.479042 0.87013
19 SER HIS PRO ARG PRO ILE ARG VAL 0.479042 0.8125
20 N7P THR SEP PRO SER TYR SET 0.475 0.871795
21 TYR TYR SER ILE ILE PRO HIS SER ILE 0.473054 0.8125
22 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.468571 0.8
23 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.465517 0.740741
24 GLU ALA ASP PRO THR GLY HIS SER TYR 0.461111 0.833333
25 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.456853 0.817073
26 ARG SER LEU SEP ALA PRO GLY ASN 0.45679 0.825
27 PHE SER HIS PRO GLN ASN THR 0.455621 0.794872
28 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.455026 0.761905
29 HIS LEU TYR PHE SER SEP ASN 0.454545 0.765432
30 THR PRO ARG ARG SER MLZ SER ALA 0.454545 0.765432
31 SER ARG SEP SER PRO 0.452703 0.842105
32 SER SER PHE TYR PRO SEP ALA GLU GLY 0.452381 0.822785
33 ARG THR PHE SER PRO THR TYR GLY LEU 0.451977 0.82716
34 PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU 0.451613 0.740741
35 PIV HIS PRO PHE HIS LPL TYR TYR SER 0.450549 0.743902
36 LYS TYR TYR SER ILE ILE PRO HIS SER ILE 0.450292 0.8125
37 ARG SER ALA SEP GLU PRO SER LEU 0.450292 0.8375
38 GLY HIS ARG PRO 0.449664 0.730769
39 PRO SER TYR SEP PRO THR SEP PRO SER 0.448485 0.87013
40 ARG ARG GLU VAL HIS THR TYR TYR 0.447059 0.7625
41 ARG HIS ARG MLY VAL LEU ARG ASP TYR 0.445714 0.75
42 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.445055 0.839506
43 HIS SER ILE THR TYR LEU LEU PRO VAL 0.44382 0.8125
44 TYR PRO LYS ARG ILE ALA 0.443114 0.78481
45 ARG TYR PRO LEU THR PHE GLY TRP 0.442708 0.817073
46 ARG THR PRO SEP LEU PRO THR 49F 0.441718 0.871795
47 ARG THR PRO SEP LEU PRO THR 0.441718 0.871795
48 DHI PRO PHE HIS LEU LEU VAL TYR 0.441341 0.7375
49 SER THR GLY GLY VAL M3L LYS PRO HIS ARG 0.441026 0.797619
50 ALA VAL TYR ASP GLY ARG GLU HIS THR VAL 0.440678 0.78481
51 ALA CYS SEP PRO GLN PHE GLY 0.439759 0.782051
52 ARG THR TYR SEP GLY PRO MET ASN LYS VAL 0.438776 0.880952
53 ALA ASN SER ARG HIS PRO THR SER ILE ILE 0.438596 0.835443
54 LEU PRO PHE GLU LEU ARG GLY HIS LEU VAL 0.437838 0.7625
55 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.436782 0.7875
56 ARG TYR PRO LEU THR PHE GLY TRP CYS PHE 0.435644 0.829268
57 ALA ASN SER ARG TRP PRO THR SER ALY ILE 0.435233 0.819277
58 ALA ASN SER ARG TRP PRO ALY SER ILE ILE 0.435233 0.807229
59 ARG ARG ALA SEP ALA PRO LEU PRO 0.434524 0.835443
60 ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO 0.433526 0.797468
61 TYR SEP PRO THR SEP PRO SER 0.433121 0.87013
62 ARG MET PHE PRO ASN ALA PRO TYR LEU 0.432432 0.77907
63 ARG TYR PRO LEU THR LEU GLY TRP CYS PHE 0.430693 0.819277
64 LYS PRO HIS SER ASP 0.43038 0.74359
65 PHE PRO ARG PRO TRP LEU HIS GLY LEU 0.430052 0.756098
66 TYR ASP LEU SEP LEU PRO PHE PRO 0.429379 0.82716
67 VAL PRO LEU ARG PRO MET THR TYR 0.429379 0.795181
68 TYR LEU LYS GLU PRO VAL HIS GLY VAL 0.429348 0.75
69 ALA ARG MLZ SER ALA PRO ALA THR 0.427711 0.756098
70 ALA ASN SER ARG TRP PRO THR SER FAK ILE 0.426396 0.821429
71 ASP VAL GLN THR GLY ARG ARG PRO TYR GLU 0.425414 0.835443
72 ALA LYS PHE ARG HIS ASP 0.425 0.692308
73 ACE PHE HIS PRO ALA NH2 0.424837 0.701299
74 ALA ARG THR GLU LEU TYR ARG SER LEU 0.424242 0.6875
75 LYS PRO ILE VAL VAL LEU HIS GLY TYR 0.423913 0.740741
76 SER ASN TRP SER HIS PRO GLN PHE GLU LYS 0.42328 0.7375
77 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.423077 0.839506
78 ALA ASN SER ARG TRP PRO THR SER 2KK ILE 0.422886 0.790698
79 ALA PHE ARG ILE PRO LEU THR ARG 0.422857 0.7875
80 GLY VAL TYR ASP GLY ARG GLU HIS THR VAL 0.422222 0.78481
81 GLY HIS ARG PRO NH2 0.421053 0.727273
82 GLY ALA ARG ALA HIS SER SER 0.419355 0.721519
83 ARG PRO PRO GLY PHE SER PRO PHE ALA 0.418079 0.807692
84 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.417582 0.820513
85 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.417143 0.825
86 ARG GLU ARG SER PRO THR ARG 0.416107 0.74359
87 VAL SER GLN ASN TYR PRO ILE VAL GLN ASN 0.415205 0.7625
88 TYR PRO ASN VAL ASN ILE HIS ASN PHE 0.414365 0.756098
89 ARG VAL ALA SEP PRO THR SER GLY VAL 0.413793 0.848101
90 GLU ARG THR ILE PRO ILE THR ARG GLU 0.41358 0.782051
91 ACE PRO LEU HIS SER TPO ALA NH2 0.412121 0.85
92 DTY ILE ARG LEU LPD 0.411043 0.772152
93 ASN TRP SER HIS PRO GLN PHE GLU LYS 0.409938 0.753247
94 ALA ASN SER ARG TRP PRO THR SER 2KP ILE 0.409756 0.790698
95 ACE ARG THR PRO SEP LEU PRO THR PIP 0.409357 0.851852
96 ALA ALA ARG KCR SER ALA PRO ALA 0.406977 0.759494
97 ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR 0.40678 0.7625
98 ACE ARG THR PRO SEP LEU PRO THR 60H 0.406593 0.8875
99 ILE GLY PRO GLY ARG ALA PHE TYR ALA 0.406593 0.765432
100 ARG PHE PRO LEU THR PHE GLY TRP 0.40625 0.792683
101 ILE SER PRO ARG THR LEU ASP ALA TRP 0.406091 0.817073
102 ILE GLY PRO GLY ARG ALA PHE TYR THR 0.405405 0.777778
103 LYS VAL ALA PRO PRO ILE PRO HIS ARG 0.405405 0.7375
104 ARG PRO GLY ASN PHE LEU GLN SER ARG LEU 0.405263 0.810127
105 VAL TYR ILE HIS PRO PHE 0.404908 0.746835
106 PCA PHE ARG HIS ASP SER 0.404762 0.692308
107 ASP ARG VAL TYR ILE HIS PRO PHE 0.404624 0.716049
108 ARG HIS ARG MLZ VAL LEU ARG ASP ASN TYR 0.403226 0.72619
109 PCA PHE ARG HIS ASP SER GLY TYR GLU VAL 0.402299 0.730769
110 1IP CYS PHE SER LYS PRO ARG 0.402235 0.7875
111 HCI PRO LEU HIS SER TPO ALA NH2 0.402235 0.886076
112 PRO PRO ARG PRO ILE TYR ASN ARG ASN 0.402235 0.835443
113 ACE PRO LEU HIS SER TPO 0.401235 0.82716
114 ALA ASN SER ARG ALY PRO THR SER ILE ILE 0.401099 0.768293
115 SER LEU PHE HIS 22G THR PRO 0.40107 0.8125
116 GLY ASP CYS PHE SER LYS PRO ARG 0.4 0.772152
117 ARG VAL SER PRO SER THR SER TYR THR PRO 0.4 0.766234
118 GLY LEU LEU GLY SEP PRO VAL ARG ALA 0.4 0.8
119 PRO PRO THR LEU HIS GLU LEU TYR ASP LEU 0.4 0.8
Similar Ligands (3D)
Ligand no: 1; Ligand: ALA ARG SER HIS SEP TYR PRO ALA; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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