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Receptor
PDB id Resolution Class Description Source Keywords
1PTR 2.2 Å EC: 2.7.1.- PROTEIN KINASE C DELTA CYS2 DOMAIN COMPLEXED WITH PHORBOL- 13-ACETATE MUS MUSCULUS PHOSPHOTRANSFERASE
Ref.: CRYSTAL STRUCTURE OF THE CYS2 ACTIVATOR-BINDING DOMAIN OF PROTEIN KINASE C DELTA IN COMPLEX WITH PHORBOL ESTER. CELL(CAMBRIDGE,MASS.) V. 81 917 1995
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PRB A:3;
Valid;
none;
submit data
406.469 C22 H30 O7 C[C@@...
ZN A:1;
A:2;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1PTR 2.2 Å EC: 2.7.1.- PROTEIN KINASE C DELTA CYS2 DOMAIN COMPLEXED WITH PHORBOL- 13-ACETATE MUS MUSCULUS PHOSPHOTRANSFERASE
Ref.: CRYSTAL STRUCTURE OF THE CYS2 ACTIVATOR-BINDING DOMAIN OF PROTEIN KINASE C DELTA IN COMPLEX WITH PHORBOL ESTER. CELL(CAMBRIDGE,MASS.) V. 81 917 1995
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 1PTR - PRB C22 H30 O7 C[C@@H]1[C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 1PTR - PRB C22 H30 O7 C[C@@H]1[C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 1PTR - PRB C22 H30 O7 C[C@@H]1[C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PRB; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 PRB 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1PTR; Ligand: PRB; Similar sites found with APoc: 270
This union binding pocket(no: 1) in the query (biounit: 1ptr.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1OBD AMP None
2 4K49 HFQ None
3 3NKV GNP None
4 4GOJ GNP None
5 4ZI2 GNP None
6 2CYE COA None
7 3R35 4CO None
8 3RAB GNP None
9 5DEY 59T None
10 6CEP OXM None
11 6CEP NAD None
12 5O1I 9GH None
13 2CUL FAD None
14 4O33 3PG None
15 4O33 TZN None
16 5XC5 GTP None
17 6DEF GCP None
18 4K4D HFQ None
19 1VPM COA None
20 1KSH GDP None
21 1WN3 HXC None
22 4ZRB COA None
23 4IEN COA None
24 3T34 GDP None
25 3BJK CIT None
26 4GAH 0ET None
27 1J2J GTP None
28 1DJL NAP None
29 2WBP ZZU None
30 2WBP SIN None
31 3DDC GNP None
32 5LEF GTP None
33 2VG1 FPP None
34 1AKV FMN None
35 2V1O COA None
36 3D04 SAK None
37 1PZG A3D None
38 4QAR ADE None
39 1K27 MTM None
40 1LDN NAD None
41 1XOC VAL ASP SER LYS ASN THR SER SER TRP None
42 3SBD GNP None
43 5J62 FMN None
44 4P25 FUC GAL NAG FUC None
45 2AKO ADP None
46 3BC1 GNP None
47 1YBU APC None
48 4RHS SIA SIA GAL None
49 1Q5H DUD None
50 1UPT GTP None
51 3KEE 30B None
52 1S4M LUM None
53 5MVR ADP None
54 1MH1 GNP None
55 2HJR APR None
56 6BQK Z1E None
57 3HDY FDA None
58 1V9A SAH None
59 9LDB NAD None
60 3JSX CC2 None
61 3HDY GDU None
62 3LL5 ADP None
63 3LL5 IPE None
64 3LL5 ATP None
65 2VL8 CTS None
66 1F3F D4D None
67 1F3F D4T None
68 4PVD NDP None
69 9LDT NAD None
70 1MDB AMP DBH None
71 1LOF MAN BMA NAG NAG MAN NAG GAL GAL None
72 3DEF GDP None
73 1I52 CTP None
74 5B4T 3HR None
75 5B4T NAD None
76 3G5D 1N1 None
77 3FUU ADN None
78 3P8N L4T None
79 2Q2V NAD None
80 3WV1 WHH None
81 1TU3 GNP None
82 1MMQ RRS None
83 1X1T NAD None
84 1WPY BTN None
85 2FV5 541 None
86 6MB9 COA None
87 6MB9 NMY None
88 5YPU ATP None
89 1N2X SAM None
90 6FA4 GNP None
91 1WG8 SAM None
92 3BIY 01K None
93 1GUZ NAD None
94 2W83 GTP None
95 1Q3A NGH None
96 3KJQ B94 None
97 4NTC FAD None
98 4C0X AQN None
99 3TUT ATP None
100 2J59 GTP None
101 1D2N ANP None
102 4ONC 40B None
103 5OCG GNP None
104 2J9D ADP None
105 2IVD ACJ None
106 4Q9N NAI None
107 2OI2 DP6 None
108 1QAN SAH None
109 3JSX FAD None
110 2XCF BBQ None
111 2X1L ADN None
112 5XK9 GST None
113 4DFU QUE None
114 3FPZ AHZ None
115 1QRD FAD None
116 4N65 AQN None
117 4N65 FMN None
118 4O1M NAD None
119 4MZQ 1VU None
120 4EIL CB3 None
121 4ZFL 4NK None
122 5XK9 DMA None
123 2A8Y MTA None
124 4M20 COA None
125 5U3B 7TD None
126 1OIX GDP None
127 5L9O GOP None
128 1ZHS NAG NAG BMA MAN MAN None
129 3GFS FMN None
130 1EZ4 NAD None
131 2W2X GSP None
132 2PHN GDP None
133 2C5L GTP None
134 5HV7 RBL 0.458716
135 4CZG QH3 0.574713
136 4CZG ADP 0.574713
137 4DQ2 BTX 0.609756
138 2E1T MLC 4
139 1VG8 GNP 4
140 1KY8 NAP 4
141 1CT9 GLN 4
142 5M58 SAH 4
143 1YOA FAD 4
144 4HZO COA 4
145 1TV5 FMN 4
146 1PNO NAP 4
147 5JFT ACE ASP GLU VAL ASP 0QE 4
148 5YYF PHQ GLN THR ALA ARG LYS NH2 FOA 4
149 3A7R LAQ 6
150 5DI3 GNP 6
151 3DOE GTP 6
152 4M9Q GNP 6
153 1RE0 AFB 6
154 2GKS ADP 6
155 5XFV FMN 6
156 3QBT GNP 6
157 1Q7B NAP 6
158 4L2I FAD 6
159 4PLG OXM 6
160 4PLG NAI 6
161 3LL9 ADP 6
162 4CQM NAP 6
163 4POW OP1 6
164 2OWZ CIT 6
165 1M5B BN1 8
166 4K81 GTP 8
167 4HDQ GNP 8
168 5WM2 SAL 8
169 5WM2 AMP 8
170 5WDR GNP 8
171 2Z49 AMG 8
172 4NDO ATP 8
173 4KP7 NAP 8
174 4Z94 ATP 8
175 1QD1 FON 8
176 4KP7 1UQ 8
177 2FXU ATP 8
178 1GTE IUR 8
179 1GTE FMN 8
180 4KVG GTP 8
181 1NF3 GNP 8
182 1E96 GTP 8
183 4CBU ATP 8
184 4PKI ATP 8
185 3X1Z GNP 8
186 4HDO GNP 8
187 3L9W FMN 8
188 5ZZA ATP 8
189 4R4U COA 10
190 2FFQ GSP 10
191 1TL2 NDG 10
192 1NVV GNP 10
193 2ZBA COA 10
194 6BVJ GNP 10
195 3O84 HTJ 10
196 6BVM GNP 10
197 4RPL 3UC 10
198 4RPL FAD 10
199 1OVD FMN 10
200 1OVD ORO 10
201 6D59 GNP 10
202 6D5M GNP 10
203 6D5L GNP 10
204 6D5V GNP 10
205 6D55 GNP 10
206 6D56 GNP 10
207 6D5G GNP 10
208 2BHZ MAL 10
209 6D5J GNP 10
210 6BVI GNP 10
211 6D5H GNP 10
212 5IBP ACE ASP GLU VAL ASP 0QE 10
213 6BVL GNP 10
214 6B92 SAH 10
215 4BMO FMN 10
216 6BVK GNP 10
217 6D5E GNP 10
218 3KIH GDL 10
219 3B7G ANP 10
220 5NGZ 2BG 12
221 2UZI GTP 12
222 4POO SAM 12
223 3KV8 FAH 12
224 3GVL SLB SIA 12
225 4HXY NDP 12
226 2AJ4 ANP 12
227 1RP0 AHZ 12
228 3TWO NDP 12
229 5EE5 GTP 12
230 3IES M24 12
231 1J09 GLU 12
232 1J09 ATP 12
233 5C2N NAG 12.5
234 5LXT 7AK 14
235 5LXT GDP 14
236 3A1I UNU 14
237 2RKV COA 14
238 2FNA ADP 14
239 5UWU GNP 14
240 5KBZ 3B2 14
241 1M2K APR 14
242 5YRV 5AD 14
243 5VKT NAP 14
244 1HYE NAP 14
245 5ARK UMP 16
246 1PN4 HDC 16
247 3H11 ALA ILE GLU THR ASA 16
248 6GAQ FMN 16
249 1M2W NAD 16
250 4PLT NAI 16
251 4PLT OXM 16
252 2PAV ATP 16
253 1XA4 COA 16
254 1LJ8 NAD 16
255 5XWV NDP 18
256 2E5A LAQ 18
257 2B8W ALF 5GP 18
258 5O96 SAM 18
259 3U4L ATP 18
260 3PPM JG1 20
261 1GUA GNP 20
262 2ODE ALF GDP 20
263 3PC3 P1T 20
264 4Z87 GDP 20
265 1MHW BP4 CYS DAR TYR PEA 21.4286
266 2VVL FAD 22
267 2RNF UM3 22
268 5EHZ 5NZ 26
269 3F5O UOC COA 34
270 5J6D 6H5 38
Pocket No.: 2; Query (leader) PDB : 1PTR; Ligand: PRB; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1ptr.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
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