Receptor
PDB id Resolution Class Description Source Keywords
1P4N 1.9 Å EC: 2.3.2.10 CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMX:UDP-MURNAC- PENTAPEPTIDE COMPLEX WEISSELLA VIRIDESCENS FEMX TRANSFERASE-TRANSFERASE SUBSTRATE COMPLEX
Ref.: CRYSTAL STRUCTURES OF WEISSELLA VIRIDESCENS FEMX AN COMPLEX WITH UDP-MURNAC-PENTAPEPTIDE: INSIGHTS INTO FAMILY SUBSTRATES RECOGNITION. STRUCTURE V. 12 257 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:341;
A:342;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MG A:401;
A:582;
A:683;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
UMA FGA LYS DAL DAL B:336;
Valid;
none;
submit data
1132.94 n/a [P+](...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4II9 1.66 Å EC: 2.3.2.10 CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMXVV NON-RIBOSO ACID TRANSFERASE IN COMPLEX WITH A PEPTIDYL-RNA CONJUGATE WEISSELLA VIRIDESCENS FEMX PEPTIDOGLYCAN TRANSFERASE PEPTIDYL-RNA CONJUGATE COMTRANSFERASE-PEPTIDE-RNA COMPLEX
Ref.: THE STRUCTURE OF FEMXWV IN COMPLEX WITH A PEPTIDYL-CONJUGATE: MECHANISM OF AMINOACYL TRANSFER FROM ALA-TRNA(ALA) TO PEPTIDOGLYCAN PRECURSORS ANGEW.CHEM.INT.ED.ENGL. V. 52 7278 2013
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1P4N - UMA FGA LYS DAL DAL n/a n/a
2 4II9 ic50 = 70 nM UDP ALA FGA CYS DAL DAL MUB C C A9Z n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1P4N - UMA FGA LYS DAL DAL n/a n/a
2 4II9 ic50 = 70 nM UDP ALA FGA CYS DAL DAL MUB C C A9Z n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1P4N - UMA FGA LYS DAL DAL n/a n/a
2 4II9 ic50 = 70 nM UDP ALA FGA CYS DAL DAL MUB C C A9Z n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: UMA FGA LYS DAL DAL; Similar ligands found: 17
No: Ligand ECFP6 Tc MDL keys Tc
1 UMA FGA LYS DAL DAL 1 1
2 UAG API 0.666667 0.974026
3 UAG 0.546512 0.923077
4 UMA 0.54321 0.871795
5 UML 0.535912 0.962025
6 UDP ALA FGA CYS DAL DAL MUB C C A9Z 0.488 0.808511
7 EPZ 0.487654 0.871795
8 AMV ALA FGA LYS DAL DAL 0.461988 0.705128
9 UDP GAL 0.460526 0.87013
10 EEB 0.457831 0.860759
11 PMP UD1 0.423913 0.831325
12 UD2 0.417178 0.858974
13 UD1 0.417178 0.858974
14 U20 0.414365 0.890244
15 U21 0.414365 0.890244
16 EPU 0.406977 0.8375
17 UD7 0.403614 0.858974
Similar Binding Sites (Proteins are less than 50% similar to leader)
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