Receptor
PDB id Resolution Class Description Source Keywords
1P1C 2.5 Å EC: 2.1.1.2 GUANIDINOACETATE METHYLTRANSFERASE WITH GD ION RATTUS NORVEGICUS GUANIDINOACETATE METHYLTRANSFERASE METHYLTRANSFERASE GD ION S-ADENOSYLHOMOCYSTEINE
Ref.: MONOCLINIC GUANIDINOACETATE METHYLTRANSFERASE AND GADOLINIUM ION-BINDING CHARACTERISTICS. ACTA CRYSTALLOGR.,SECT.D V. 59 1589 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GD3 A:3001;
Invalid;
none;
submit data
157.25 Gd [Gd+3...
SAH A:2001;
B:2002;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1P1C 2.5 Å EC: 2.1.1.2 GUANIDINOACETATE METHYLTRANSFERASE WITH GD ION RATTUS NORVEGICUS GUANIDINOACETATE METHYLTRANSFERASE METHYLTRANSFERASE GD ION S-ADENOSYLHOMOCYSTEINE
Ref.: MONOCLINIC GUANIDINOACETATE METHYLTRANSFERASE AND GADOLINIUM ION-BINDING CHARACTERISTICS. ACTA CRYSTALLOGR.,SECT.D V. 59 1589 2003
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1KHH - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1P1C - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1KHH - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1P1C - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1XCJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 1XCL - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1KHH - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1P1C - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1XCJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 1XCL - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1P1C; Ligand: SAH; Similar sites found: 590
This union binding pocket(no: 1) in the query (biounit: 1p1c.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3A27 SAM 0.00002829 0.51232 None
2 1NV8 SAM 0.0002203 0.46468 None
3 1NV8 MEQ 0.0002009 0.46468 None
4 1BW9 NAD 0.0003723 0.45044 None
5 1GV0 NAD 0.0005533 0.44956 None
6 1BXG NAD 0.0007706 0.4389 None
7 1ZN7 HSX 0.004487 0.43588 None
8 1C1X NAD 0.0004891 0.42314 None
9 1ZEM NAD 0.002658 0.41674 None
10 5CLO NS8 0.02115 0.41387 None
11 5C2N NAG 0.02055 0.41326 None
12 1SOW NAD 0.0001677 0.47432 1.00503
13 1I2B NAD 0.004728 0.43339 1.00503
14 1KYQ NAD 0.00000308 0.56124 1.50754
15 2PT9 2MH 0.00005957 0.49632 1.50754
16 2PT9 S4M 0.00002902 0.49562 1.50754
17 5GVR LMR 0.002769 0.48659 1.50754
18 1PZM 5GP 0.001752 0.4613 1.50754
19 2AOT SAH 0.00005487 0.44759 1.50754
20 2EFJ SAH 0.0001765 0.43952 1.50754
21 1S7G APR 0.001777 0.4324 1.50754
22 2I7C AAT 0.00005065 0.42665 1.50754
23 5FTW SAH 0.00261 0.41882 1.50754
24 2PX8 SAH 0.001262 0.41003 1.50754
25 1JQD SAH 0.0004705 0.40915 1.50754
26 1S7G NAD 0.005998 0.40755 1.50754
27 1DKU AP2 0.01637 0.40651 1.50754
28 1XHL NDP 0.008794 0.40176 1.50754
29 1HGX 5GP 0.004485 0.44069 1.63934
30 4JLS 3ZE 0.02404 0.41055 1.97368
31 1J0X NAD 0.0000809 0.5024 2.01005
32 3CIF NAD 0.0001734 0.469 2.01005
33 3CIF G3H 0.0003937 0.46281 2.01005
34 5LD5 NAD 0.0004417 0.44354 2.01005
35 1EBF NAD 0.0005203 0.44248 2.01005
36 4IF4 BEF 0.00428 0.4387 2.01005
37 5JSQ 6MS 0.01164 0.41143 2.01005
38 3QH2 3NM 0.0244 0.40752 2.01005
39 5G3U FDA 0.00007696 0.4025 2.01005
40 1M2K APR 0.001816 0.40081 2.01005
41 2HMT NAI 0.00001833 0.49419 2.08333
42 5FA8 SAM 0.0002445 0.45395 2.48447
43 1REO FAD 0.00003849 0.51147 2.51256
44 2GVC FAD 0.00003316 0.50558 2.51256
45 1P77 ATR 0.0003326 0.50435 2.51256
46 1PS9 FAD 0.0001774 0.48517 2.51256
47 2EJU SAH 0.0001309 0.48311 2.51256
48 3T31 FAD 0.0004184 0.4808 2.51256
49 3T31 DCQ 0.0004575 0.48076 2.51256
50 4C3Y FAD 0.000286 0.47614 2.51256
51 1DSS NAD 0.00008744 0.47599 2.51256
52 4C3Y ANB 0.000462 0.47235 2.51256
53 1I1N SAH 0.000174 0.46726 2.51256
54 1MV8 NAD 0.0004814 0.44732 2.51256
55 1GAD NAD 0.000688 0.44093 2.51256
56 4LWP SAH 0.0001908 0.43685 2.51256
57 3RKR NAP 0.005103 0.43313 2.51256
58 1VQW FAD 0.00003546 0.43078 2.51256
59 1HDG NAD 0.0005866 0.42627 2.51256
60 2EV9 NAP 0.002626 0.42394 2.51256
61 1ZH8 NAP 0.002208 0.42157 2.51256
62 2GV8 FAD 0.00004732 0.42117 2.51256
63 1O97 AMP 0.01021 0.41902 2.51256
64 3U4C NDP 0.002996 0.4175 2.51256
65 3RIY NAD 0.003966 0.41379 2.51256
66 2HK9 NAP 0.003541 0.41159 2.51256
67 3EVG SAH 0.001497 0.40883 2.51256
68 1PS9 NAP 0.004524 0.4072 2.51256
69 4REP FAD 0.00006723 0.40029 2.51256
70 3Q3C NAD 0.003308 0.4097 2.67559
71 1VBO MAN 0.01541 0.41347 2.68456
72 1EJ0 SAM 0.00002918 0.47226 2.77778
73 4YMH SAH 0.0000008131 0.56667 3.01508
74 1I8T FAD 0.00002683 0.51825 3.01508
75 1WG8 SAM 0.000009786 0.51284 3.01508
76 2WPF WPF 0.000359 0.50807 3.01508
77 2CDU FAD 0.00005207 0.50172 3.01508
78 1GR0 NAD 0.00005903 0.49649 3.01508
79 2WPF FAD 0.0006134 0.49535 3.01508
80 1G55 SAH 0.00005931 0.49305 3.01508
81 4NTC FAD 0.0001705 0.48593 3.01508
82 4J4H 1J1 0.0002481 0.48428 3.01508
83 4J4H NAI 0.0002481 0.48428 3.01508
84 4J36 FAD 0.0001461 0.47832 3.01508
85 4J36 1HR 0.0003348 0.47538 3.01508
86 2G5C NAD 0.0001506 0.47318 3.01508
87 2O4C NAD 0.0001748 0.47204 3.01508
88 4POO SAM 0.00009863 0.47193 3.01508
89 2CDU ADP 0.00002134 0.467 3.01508
90 4EUE NAI 0.000326 0.46215 3.01508
91 2P41 SAH 0.0007185 0.45062 3.01508
92 1KPG SAH 0.0005267 0.44421 3.01508
93 3GGO NAI 0.00161 0.44346 3.01508
94 3GGO ENO 0.00161 0.44346 3.01508
95 1R37 NAD 0.001216 0.44066 3.01508
96 3V1Y NAD 0.000188 0.4393 3.01508
97 3GMB FAD 0.001615 0.43543 3.01508
98 2WA2 SAM 0.0002905 0.42794 3.01508
99 4KRG SAH 0.0002952 0.42781 3.01508
100 2UYQ SAM 0.01371 0.42281 3.01508
101 2B4R AES 0.000211 0.42124 3.01508
102 1L7E NAI 0.001837 0.42013 3.01508
103 1VE3 SAM 0.003863 0.41851 3.01508
104 1XSE NDP 0.006247 0.41681 3.01508
105 2B4R NAD 0.0002142 0.41662 3.01508
106 2IVD FAD 0.00004877 0.4159 3.01508
107 3NZ1 3NY 0.01768 0.41578 3.01508
108 3VPH OXM 0.0001079 0.40606 3.01508
109 3JWH SAH 0.0006882 0.40195 3.01508
110 4PQG NAG 0.02827 0.40011 3.13112
111 2IZ1 ATR 0.00003763 0.55996 3.51759
112 2PWY SAH 0.000001482 0.54386 3.51759
113 1RP0 AHZ 0.00001392 0.51987 3.51759
114 3FUU ADN 0.00001532 0.51834 3.51759
115 1MO9 FAD 0.0001673 0.51495 3.51759
116 1MO9 KPC 0.0002439 0.50792 3.51759
117 1BZL FAD 0.0003832 0.50565 3.51759
118 2O07 MTA 0.000004169 0.49303 3.51759
119 5JCM ISD 0.0004747 0.48555 3.51759
120 5JCM NAD 0.0004747 0.48555 3.51759
121 5JCM FAD 0.0004572 0.48555 3.51759
122 4DMG SAM 0.0003424 0.48505 3.51759
123 2O07 SPD 0.000005172 0.476 3.51759
124 4AT0 FAD 0.0004915 0.47215 3.51759
125 1X7D ORN 0.0002933 0.47086 3.51759
126 4UCI SAM 0.0002216 0.46842 3.51759
127 1X7D NAD 0.0001975 0.46665 3.51759
128 1J49 NAD 0.0002246 0.46433 3.51759
129 1TDF FAD 0.0008319 0.46106 3.51759
130 1TDF NAP 0.002114 0.45907 3.51759
131 3H2B SAH 0.00008754 0.45649 3.51759
132 1FL2 FAD 0.0007377 0.45599 3.51759
133 5UAO FAD 0.0007487 0.45456 3.51759
134 1UXG NAD 0.0008603 0.45196 3.51759
135 1R6D DAU 0.001706 0.45168 3.51759
136 1R6D NAD 0.001781 0.45168 3.51759
137 4K28 NAD 0.0001472 0.44906 3.51759
138 3QOX SAH 0.0004528 0.4431 3.51759
139 5AHO TLA 0.003705 0.44009 3.51759
140 4N49 SAM 0.0004758 0.43537 3.51759
141 3BXO SAM 0.0001347 0.43305 3.51759
142 2NAD NAD 0.002935 0.42558 3.51759
143 5GWX SAR 0.0005261 0.4254 3.51759
144 5GWX SAM 0.0005261 0.4254 3.51759
145 3CH6 311 0.009079 0.42476 3.51759
146 3CH6 NAP 0.009079 0.42476 3.51759
147 1CF2 NAP 0.002411 0.41848 3.51759
148 2YYY NAP 0.004277 0.41106 3.51759
149 1VKO NAD 0.0003035 0.40899 3.51759
150 2W58 ADP 0.03413 0.40431 3.51759
151 1ZGS XMM 0.03807 0.40323 3.51759
152 1JJ7 ADP 0.04414 0.40041 3.51759
153 5TTJ FAD 0.00006095 0.40007 3.51759
154 3P2E SAH 0.001019 0.43605 3.55556
155 4P83 U5P 0.004972 0.43368 3.84615
156 1E6E FAD 0.00007904 0.49396 3.90625
157 3L9W AMP 0.000002082 0.55279 4.0201
158 2F5Z FAD 0.000006307 0.55094 4.0201
159 3L9W GSH 0.000002418 0.54619 4.0201
160 3LXD FAD 0.00008389 0.49145 4.0201
161 2VDV SAM 0.0003508 0.47907 4.0201
162 1ZMD NAI 0.00003009 0.47629 4.0201
163 3GU3 SAH 0.0009316 0.46949 4.0201
164 3S1S SAH 0.000214 0.4563 4.0201
165 5E72 SAM 0.0002676 0.44897 4.0201
166 2ZIF SAM 0.0002189 0.44272 4.0201
167 2HJR APR 0.0004996 0.44137 4.0201
168 1KEW NAD 0.004433 0.4323 4.0201
169 1BXK NAD 0.001388 0.43141 4.0201
170 1EZ4 NAD 0.0003803 0.42775 4.0201
171 5KOK SAH 0.002264 0.42499 4.0201
172 3GFB NAD 0.0003722 0.42336 4.0201
173 1MUU NAD 0.0008457 0.42035 4.0201
174 3GCZ SAM 0.0007027 0.41942 4.0201
175 1O0S NAI 0.001914 0.41771 4.0201
176 2DTX BMA 0.006273 0.41574 4.0201
177 1CDO NAD 0.00304 0.41433 4.0201
178 3FPF MTA 0.00004401 0.41319 4.0201
179 3FPF TNA 0.00004401 0.41319 4.0201
180 2Y6Q FAD 0.0001997 0.41304 4.0201
181 1V5F FAD 0.02321 0.40725 4.0201
182 1ZMD FAD 0.00000723 0.40703 4.0201
183 3RNM FAD 0.0000105 0.40339 4.0201
184 5N53 8NB 0.0000556 0.55005 4.10256
185 1SQL GUN 0.01896 0.41556 4.10959
186 1RL4 BRR 0.01778 0.41471 4.25532
187 5TUK FAD 0.0008326 0.40177 4.41176
188 1QAN SAH 0.000003991 0.53186 4.52261
189 3GDH SAH 0.000009991 0.5032 4.52261
190 9LDT NAD 0.0000604 0.49141 4.52261
191 5BUK FAD 0.0001597 0.49058 4.52261
192 3WLE NAD 0.0002097 0.47581 4.52261
193 3GDN FAD 0.0004784 0.46752 4.52261
194 3GDN HBX 0.0007221 0.46752 4.52261
195 3L4S 3PG 0.0002712 0.46696 4.52261
196 3L4S NAD 0.0002506 0.46696 4.52261
197 1YKJ FAD 0.001168 0.46618 4.52261
198 3X0D SAH 0.00009647 0.45455 4.52261
199 1U2Z SAH 0.0003066 0.44997 4.52261
200 5JE8 NAD 0.0002264 0.44264 4.52261
201 1KPH SAH 0.0004897 0.43835 4.52261
202 9LDB NAD 0.00006562 0.43084 4.52261
203 3KLJ FAD 0.00004277 0.42888 4.52261
204 4KIB SAH 0.0003297 0.42828 4.52261
205 3GEG NAD 0.001556 0.42786 4.52261
206 5VN0 NAI 0.0004787 0.42421 4.52261
207 4PNE SAH 0.001417 0.423 4.52261
208 1NM5 NAD 0.007535 0.42275 4.52261
209 1PJS NAD 0.000546 0.41755 4.52261
210 1VJT NAD 0.0009019 0.41617 4.52261
211 2JKY 5GP 0.008195 0.41481 4.52261
212 5E9W SAH 0.000266 0.41452 4.52261
213 1NM5 NAP 0.01142 0.41388 4.52261
214 2A92 NAI 0.0001795 0.41344 4.52261
215 3JV7 NAD 0.0003274 0.41302 4.52261
216 3LRE ADP 0.01842 0.40553 4.52261
217 3GXO SAH 0.01128 0.40467 4.52261
218 3AB4 LYS 0.01128 0.40467 4.52261
219 2GCG DGY 0.03103 0.403 4.52261
220 1JWY ADP 0.01867 0.4015 4.52261
221 1VI2 NAD 0.005804 0.40108 4.52261
222 5T46 MGP 0.02198 0.41159 4.54545
223 2HNK SAH 0.0000215 0.48606 4.60251
224 2B9W FAD 0.0007467 0.47032 4.71698
225 3IHG FAD 0.0001241 0.47504 4.85981
226 1PNO NAP 0.006017 0.4062 5
227 2RAB NAD 0.00002169 0.54788 5.02513
228 2RAB FAD 0.000007925 0.54788 5.02513
229 1Y8Q ATP 0.0000006612 0.54776 5.02513
230 5OFW 9TW 0.0003131 0.51216 5.02513
231 4M38 SAH 0.00003374 0.49846 5.02513
232 5X62 SAH 0.00007759 0.49838 5.02513
233 2V3A FAD 0.00007285 0.49818 5.02513
234 4CNK FAD 0.00008342 0.49565 5.02513
235 4M37 SAH 0.0000257 0.47849 5.02513
236 1FEC FAD 0.0005473 0.4691 5.02513
237 1DXY NAD 0.0001619 0.46682 5.02513
238 3DMH SAM 0.0002005 0.46582 5.02513
239 1A5Z NAD 0.0004025 0.44904 5.02513
240 1KC7 PPR 0.006774 0.43793 5.02513
241 4ONQ SFG 0.001587 0.4355 5.02513
242 1TPY SAH 0.0007091 0.43207 5.02513
243 2YY7 NAD 0.001699 0.43058 5.02513
244 5ULP KB1 0.0006912 0.43033 5.02513
245 3MQ2 SAH 0.003692 0.42309 5.02513
246 3DMH GMP 0.0004333 0.42247 5.02513
247 4ZGS NAD 0.001725 0.42124 5.02513
248 5JE0 AZ8 0.0002149 0.41859 5.02513
249 5JE0 SAH 0.0002149 0.41859 5.02513
250 2IXB NAD 0.000236 0.41673 5.02513
251 2BZG SAH 0.0007993 0.41644 5.02513
252 1ORR NAD 0.004304 0.41612 5.02513
253 2XZ9 PYR 0.01972 0.41369 5.02513
254 3O03 NAP 0.003253 0.41311 5.02513
255 4RSL FAD 0.00007541 0.41261 5.02513
256 4E13 NAD 0.001811 0.40948 5.02513
257 4UP4 GAL NAG 0.01828 0.40321 5.02513
258 4RQU NAD 0.0009865 0.40264 5.02513
259 2V3B FAD 0.00009132 0.40166 5.02513
260 2WSB NAD 0.004945 0.42123 5.11811
261 2OOR NAD 0.000849 0.43563 5.17241
262 3Q87 SAM 0.000391 0.44568 5.29412
263 3EGI ADP 0.00001913 0.56855 5.52764
264 3SQP FAD 0.0001119 0.55353 5.52764
265 1V8B NAD 0.00003178 0.51089 5.52764
266 2BRY FAD 0.00002906 0.508 5.52764
267 2XVF FAD 0.0000402 0.50794 5.52764
268 4USQ FAD 0.00006612 0.4944 5.52764
269 3CGD NAD 0.0005328 0.49074 5.52764
270 3CGD COA 0.0005328 0.49074 5.52764
271 3CGD FAD 0.0005328 0.49074 5.52764
272 3CTY FAD 0.0001942 0.48685 5.52764
273 1T26 NAI 0.0002132 0.48284 5.52764
274 5MPT SAH 0.0001344 0.4826 5.52764
275 3QVP FAD 0.0004943 0.46797 5.52764
276 2VYN NAD 0.0002302 0.46388 5.52764
277 3M6W SAM 0.0009581 0.45388 5.52764
278 4KOA NDP 0.0009714 0.44913 5.52764
279 2PS1 ORO 0.003568 0.44571 5.52764
280 1MZV AMP 0.002974 0.44468 5.52764
281 4TXI FAD 0.00002182 0.44135 5.52764
282 1F8G NAD 0.0007088 0.43888 5.52764
283 1G60 SAM 0.001188 0.43704 5.52764
284 3MBI HSX 0.005455 0.43639 5.52764
285 3BGD SAH 0.0008033 0.433 5.52764
286 3FPZ AHZ 0.03463 0.43056 5.52764
287 5CUQ NSC 0.001844 0.43042 5.52764
288 1QB7 ADE 0.007436 0.42506 5.52764
289 1XDS SAM 0.005267 0.42385 5.52764
290 5E1M PRO PRO LYS ARG ILE ALA 0.00006823 0.42111 5.52764
291 5E1M SAH 0.00006823 0.42111 5.52764
292 3ITJ CIT 0.01292 0.42101 5.52764
293 2J5V PCA 0.01824 0.41253 5.52764
294 3Q9T FAY 0.007304 0.41186 5.52764
295 3BGD PM6 0.0009812 0.40878 5.52764
296 1HYH NAD 0.0004089 0.40675 5.52764
297 4D42 NAP 0.01859 0.40362 5.52764
298 4D42 W0I 0.01859 0.40362 5.52764
299 1QZZ SAM 0.01494 0.40251 5.52764
300 5KVA SAM 0.0000016 0.54827 5.7554
301 3VYW SAM 0.000000269 0.58692 6.03015
302 1X87 NAD 0.000002208 0.53684 6.03015
303 3AD8 NAD 0.00002038 0.51611 6.03015
304 2C7G ODP 0.0001265 0.50416 6.03015
305 2C7G FAD 0.0001339 0.50398 6.03015
306 4BV6 FAD 0.00007663 0.50104 6.03015
307 3A25 SAM 0.00006662 0.49599 6.03015
308 1JNR FAD 0.0006742 0.48406 6.03015
309 4MIG G3F 0.0003442 0.47999 6.03015
310 4OBW SAM 0.0002175 0.47342 6.03015
311 3PT9 SAH 0.00002338 0.47293 6.03015
312 3AD8 FAD 0.001085 0.46978 6.03015
313 1N2X SAM 0.0001406 0.4637 6.03015
314 3NTD FAD 0.0004676 0.46338 6.03015
315 2DFV NAD 0.0004006 0.45227 6.03015
316 3NT6 FAD 0.0008543 0.45209 6.03015
317 2Q28 ADP 0.0007225 0.44634 6.03015
318 3LKZ SFG 0.0007839 0.44482 6.03015
319 1WDK NAD 0.0004721 0.44236 6.03015
320 1SB8 NAD 0.003643 0.43358 6.03015
321 1SB8 UD2 0.004324 0.43358 6.03015
322 5AGR A52 0.003076 0.43063 6.03015
323 2AG8 NAP 0.0006301 0.42812 6.03015
324 2C31 TZD 0.01225 0.42421 6.03015
325 2C31 ADP 0.01191 0.42421 6.03015
326 4L8V NAP 0.002795 0.42015 6.03015
327 2DC1 NAD 0.003007 0.416 6.03015
328 1E5Q NDP 0.0008681 0.4057 6.03015
329 3EF0 ALF 0.02204 0.40491 6.03015
330 1U1I NAD 0.000267 0.40127 6.03015
331 3GD4 NAD 0.005031 0.40066 6.03015
332 1L3I SAH 0.00000767 0.52139 6.25
333 3OA2 NAD 0.000238 0.42113 6.28931
334 3H8V ATP 0.000008855 0.48755 6.50685
335 1ZQ9 SAM 0.00000004427 0.63554 6.53266
336 3TKA SAM 0.000002584 0.52323 6.53266
337 3SSO SAH 0.00001302 0.51589 6.53266
338 3DXY SAM 0.000106 0.5095 6.53266
339 2RGO FAD 0.00004102 0.50756 6.53266
340 2EG5 SAH 0.0001961 0.49092 6.53266
341 5FJN FAD 0.0001655 0.48765 6.53266
342 5FJN BE2 0.0001971 0.48765 6.53266
343 4C4A SAH 0.00002162 0.47933 6.53266
344 4EIP FAD 0.0003514 0.47553 6.53266
345 2RGH FAD 0.0002795 0.47542 6.53266
346 4JK3 NAD 0.0001001 0.47542 6.53266
347 1OMO NAD 0.00008737 0.47408 6.53266
348 5MGZ SAH 0.0001921 0.47109 6.53266
349 4EIP K2C 0.0005731 0.46822 6.53266
350 2PZM NAD 0.001811 0.44326 6.53266
351 2PZM UDP 0.001811 0.44326 6.53266
352 3ETG GTP 0.002239 0.44018 6.53266
353 3ETG GLU 0.003533 0.43831 6.53266
354 2V6G NAP 0.003371 0.41807 6.53266
355 2D2I NAP 0.002231 0.41669 6.53266
356 5KJW 53C 0.01839 0.41377 6.53266
357 1GY8 NAD 0.0002687 0.41318 6.53266
358 1G0N PHH 0.009702 0.40943 6.53266
359 4D7E FAD 0.00008585 0.40909 6.53266
360 1P31 EPU 0.00639 0.40889 6.53266
361 4K5S FAD 0.0002263 0.40676 6.53266
362 1G0N NDP 0.009814 0.4063 6.53266
363 3B20 NAD 0.004023 0.40623 6.53266
364 1EK6 UPG 0.02201 0.40386 6.53266
365 1G6H ADP 0.0395 0.40371 6.53266
366 2HQM FAD 0.00001549 0.40301 6.53266
367 4A6D SAM 0.008298 0.40067 6.53266
368 3B1J NAD 0.0008574 0.40064 6.53266
369 1DMR PGD 0.03593 0.40013 6.53266
370 2AWN ADP 0.0179 0.42178 6.56168
371 1GXU 2HP 0.0108 0.40707 6.59341
372 2CJU PHX 0.01833 0.41406 6.61157
373 5L95 AMP 0.00002391 0.51002 6.81004
374 1X14 NAD 0.00001588 0.52929 7.03518
375 2XVE FAD 0.00018 0.50164 7.03518
376 4TM3 FAD 0.000327 0.4952 7.03518
377 1R18 SAH 0.00005335 0.48532 7.03518
378 2VT3 ATP 0.000001654 0.47975 7.03518
379 1KNR FAD 0.0003061 0.4737 7.03518
380 1SC6 NAD 0.0001802 0.473 7.03518
381 3OJO NAD 0.0001984 0.45763 7.03518
382 1UP7 NAD 0.0004181 0.44813 7.03518
383 5T67 JHZ 0.001719 0.44619 7.03518
384 5T67 SAH 0.00142 0.44478 7.03518
385 1GUZ NAD 0.0006649 0.44472 7.03518
386 4PIO AVI 0.001011 0.44277 7.03518
387 4PIO SAH 0.001085 0.44277 7.03518
388 4IWN GEK 0.0007318 0.43464 7.03518
389 1DQN IMU 0.009195 0.42492 7.03518
390 1XHC FAD 0.00001804 0.42429 7.03518
391 4HXY NDP 0.003282 0.41856 7.03518
392 3U31 NAD 0.002256 0.41808 7.03518
393 2DBZ NAP 0.003645 0.41395 7.03518
394 4IEE AGS 0.0169 0.41151 7.03518
395 5N5D SAM 0.000002709 0.51261 7.07965
396 2YVJ NAI 0.0001075 0.48686 7.53769
397 2YVF FAD 0.0005862 0.47831 7.53769
398 2YVF NAD 0.0006097 0.47831 7.53769
399 2NXE SAM 0.0001983 0.47518 7.53769
400 3EGV SAH 0.0004339 0.46483 7.53769
401 2PXX SAH 0.0002959 0.46303 7.53769
402 5HJM MTA 0.000365 0.4591 7.53769
403 1KOL NAD 0.001026 0.4463 7.53769
404 3TLJ SAH 0.0006954 0.43554 7.53769
405 5M58 SAH 0.0006322 0.42457 7.53769
406 1NVM NAD 0.0002284 0.41548 7.53769
407 3QWI NAP 0.00557 0.41137 7.53769
408 3QWI CUE 0.009226 0.41131 7.53769
409 4PPF FLC 0.04262 0.40884 7.53769
410 1UWK NAD 0.000006503 0.40664 7.53769
411 1UWK URO 0.000006503 0.40664 7.53769
412 3LZW FAD 0.00005778 0.40434 7.53769
413 2RGJ FAD 0.0002777 0.40429 7.53769
414 1LSS NAD 0.000002592 0.54545 7.85714
415 4CVN ADP 0.02272 0.40915 8.0292
416 1SQF SAM 0.00001154 0.52942 8.0402
417 3DUW SAH 0.000003478 0.50868 8.0402
418 1DJN ADP 0.00004417 0.48408 8.0402
419 5O4J PJL 0.0001652 0.47606 8.0402
420 5O4J SAH 0.0001834 0.47557 8.0402
421 5O4J 9KH 0.0001834 0.47557 8.0402
422 1O94 ADP 0.00005807 0.47195 8.0402
423 4QTU SAM 0.0002198 0.46858 8.0402
424 3B1F NAD 0.0004854 0.44568 8.0402
425 2RBK VN4 0.01546 0.41754 8.0402
426 2XVM SAH 0.0003171 0.41572 8.0402
427 3AXB FAD 0.00002807 0.41534 8.0402
428 1RM4 NDP 0.003174 0.41503 8.0402
429 3WV8 ATP 0.00000692 0.53319 8.54271
430 1V59 FAD 0.00002238 0.52927 8.54271
431 2JJQ SAH 0.0001601 0.49505 8.54271
432 1V59 NAD 0.000001564 0.48553 8.54271
433 2VHW NAI 0.0002197 0.47495 8.54271
434 3CMC NAD 0.003217 0.44807 8.54271
435 1JQ3 AAT 0.00003442 0.43514 8.54271
436 4NEC SAH 0.002668 0.43347 8.54271
437 4XB2 NDP 0.0008271 0.43249 8.54271
438 2DT5 NAD 0.0001362 0.43218 8.54271
439 4XB2 HSE 0.001765 0.43122 8.54271
440 2FZW NAD 0.003839 0.42895 8.54271
441 3DAG FEG 0.001629 0.42391 8.54271
442 3LST SAH 0.006685 0.41897 8.54271
443 1H6C NDP 0.005606 0.41577 8.54271
444 3OU2 SAH 0.00139 0.41414 8.7156
445 3LAD FAD 0.00002998 0.52005 9.04523
446 3UCL NAP 0.0005617 0.48436 9.04523
447 3UCL CYH 0.000504 0.48436 9.04523
448 3UCL FAD 0.000504 0.48436 9.04523
449 3C3Y SAH 0.0001856 0.44648 9.04523
450 4W6Z 8ID 0.001164 0.44394 9.04523
451 4BVA NDP 0.00233 0.42481 9.04523
452 4BVA T3 0.00419 0.42229 9.04523
453 3VSE SAH 0.0002339 0.41768 9.04523
454 5MQ6 NDP 0.002459 0.41328 9.04523
455 2PV7 NAD 0.001276 0.40345 9.04523
456 1UAY ADN 0.0006418 0.46677 9.09091
457 3G89 SAM 0.0000133 0.54573 9.54774
458 3UOY NAP 0.0001856 0.5058 9.54774
459 4USR FAD 0.00003845 0.50286 9.54774
460 1LVL NAD 0.00003138 0.49978 9.54774
461 1DL5 SAH 0.000049 0.48821 9.54774
462 1PL6 572 0.001317 0.43658 9.54774
463 1PL6 NAD 0.0004325 0.43445 9.54774
464 4TQG NDP 0.002237 0.42279 9.54774
465 1LVL FAD 0.000007988 0.4048 9.54774
466 3LCC SAH 0.001504 0.40432 9.54774
467 2XYQ SAH 0.00006103 0.49766 9.83607
468 3MB5 SAM 0.0000008346 0.55397 10.0503
469 1GET NAP 0.00004426 0.53527 10.0503
470 1GET FAD 0.0000408 0.53527 10.0503
471 2NVK FAD 0.0003522 0.47221 10.0503
472 2YX1 SFG 0.0005851 0.46865 10.0503
473 4UP3 FAD 0.001006 0.45127 10.0503
474 1K3T BRZ 0.001896 0.4312 10.0503
475 4JDR FAD 0.00001507 0.40545 10.0503
476 2QA1 FAD 0.000129 0.4044 10.0503
477 5LOG SAH 0.000007702 0.53119 10.5528
478 2Q1S NAI 0.0001133 0.49599 10.5528
479 5FA5 MTA 0.0001724 0.48804 10.5528
480 2DKH 3HB 0.000228 0.47805 10.5528
481 2DKH FAD 0.0001483 0.47805 10.5528
482 5D4V SAH 0.0001096 0.47239 10.5528
483 5EB4 FAD 0.0003559 0.47086 10.5528
484 4GQB 0XU 0.0001806 0.46122 10.5528
485 4BLW AMP 0.001253 0.44011 10.5528
486 4BLW SAH 0.0009706 0.43477 10.5528
487 1OBB NAD 0.0007603 0.4281 10.5528
488 5F8F SFG 0.005725 0.41823 10.5528
489 1LDM NAD 0.0006915 0.40194 10.5528
490 5TVF CGQ 0.01425 0.40718 10.5882
491 4AZT SAM 0.0003551 0.46407 11.0553
492 4MP8 NAD 0.0005354 0.45963 11.0553
493 2FK8 SAM 0.0004671 0.45034 11.0553
494 2A14 SAH 0.0003166 0.44549 11.0553
495 5XVQ SAH 0.0005196 0.44068 11.0553
496 4AZW SAM 0.0004373 0.43235 11.0553
497 4MO2 FDA 0.00001554 0.42173 11.0553
498 4MO2 FAD 0.00002196 0.41373 11.0553
499 2GAG NAD 0.0000263 0.51586 11.1111
500 2GAG FAD 0.0005975 0.46642 11.1111
501 2GAG FOA 0.0006112 0.46599 11.1111
502 3GRU AMP 0.0000001454 0.58474 11.5578
503 4RDH AMP 0.000002968 0.56893 11.5578
504 4RDI ATP 0.000005631 0.54311 11.5578
505 4D79 ATP 0.00001018 0.53181 11.5578
506 2E5V FAD 0.0002687 0.47957 11.5578
507 4FZV SAM 0.00008025 0.46601 11.5578
508 5JJR SAH 0.0003701 0.46328 11.5578
509 1WY7 SAH 0.0001859 0.45478 11.5578
510 3T7S SAM 0.000218 0.44022 11.5672
511 1JG3 ADN 0.00000666 0.53991 12.0603
512 1I9G SAM 0.000002123 0.52604 12.0603
513 1RSG FAD 0.00002404 0.52424 12.0603
514 1YY5 FAD 0.00003227 0.52109 12.0603
515 1D4D FAD 0.00004907 0.51191 12.0603
516 3S5W FAD 0.00002146 0.51026 12.0603
517 2VVM FAD 0.0000494 0.50808 12.0603
518 1QO8 FAD 0.00006175 0.50635 12.0603
519 2AQJ FAD 0.0002765 0.49234 12.0603
520 2AQJ TRP 0.0002649 0.49234 12.0603
521 3ICR FAD 0.0001206 0.48743 12.0603
522 3ICT FAD 0.0001424 0.48434 12.0603
523 3ICS FAD 0.0001612 0.48332 12.0603
524 2JBH 5GP 0.002014 0.45825 12.0603
525 3H9E NAD 0.0002254 0.43635 12.0603
526 3ICS ADP 0.0000586 0.43244 12.0603
527 2WK1 SAH 0.0005735 0.4294 12.0603
528 3ICT ADP 0.00007015 0.42864 12.0603
529 1XTT U5P 0.005596 0.41869 12.0603
530 3BP1 GUN 0.01491 0.41807 12.0603
531 3QV1 NAD 0.0007384 0.42278 12.1951
532 4BQS ADP 0.02935 0.40331 12.5
533 1ELI PYC 0.00008714 0.49483 12.5628
534 1L1E SAH 0.0006419 0.44452 12.5628
535 3HVJ 705 0.0000003084 0.59879 13.0653
536 1H82 GZZ 0.00009403 0.51532 13.0653
537 1H82 FAD 0.00009658 0.51129 13.0653
538 1RYI FAD 0.0001864 0.48423 13.0653
539 1IM8 SAI 0.0007202 0.44241 13.0653
540 4RL4 PPV 0.01072 0.41356 13.0653
541 1HKU NAD 0.0003799 0.4075 13.0653
542 5XVK SAH 0.0003632 0.44698 13.5678
543 1CER NAD 0.0006517 0.4195 13.5678
544 5E5U MLI 0.002902 0.41328 13.5678
545 4XUC SAM 0.0000008607 0.5745 14.0704
546 4XUC 43G 0.0000008607 0.5745 14.0704
547 3NJ4 NAD 0.0003002 0.51873 14.0704
548 3G2O SAM 0.00004403 0.50389 14.0704
549 3A4T SFG 0.00002269 0.50066 14.0704
550 3NJ4 AFX 0.0008408 0.49692 14.0704
551 2DPM SAM 0.00002887 0.48667 14.0704
552 4KRI SAH 0.0003212 0.44002 14.5729
553 1PR9 NAP 0.00367 0.41905 14.5729
554 4II2 ATP 0.0000158 0.51235 15.0754
555 5BW4 SAM 0.00002208 0.47034 15.0754
556 1XTP SAI 0.00003643 0.46681 15.5779
557 2F1K NAP 0.0003612 0.42898 15.5779
558 1VM6 NAD 0.00142 0.42636 15.5779
559 1SAY PYR 0.003551 0.42087 15.5779
560 4E5N NAD 0.0005017 0.40224 15.5779
561 4NTD FAD 0.00002424 0.51878 16.0804
562 4FWE FAD 0.00003981 0.51589 16.0804
563 3C6K MTA 0.0002524 0.47237 16.0804
564 3C6K SPD 0.0002524 0.47237 16.0804
565 1LDN NAD 0.0009058 0.44205 16.0804
566 1Q0S SAH 0.0000131 0.50767 16.5829
567 1BC5 SAH 0.003528 0.40692 16.5829
568 1LTH NAD 0.0003136 0.42558 17.5879
569 1F3L SAH 0.0000602 0.48315 18.0905
570 1N4W FAD 0.0002487 0.48104 18.0905
571 2GDZ NAD 0.003185 0.41778 18.0905
572 3OFK SAH 0.00003263 0.49414 18.593
573 3F8D FAD 0.001503 0.46594 18.593
574 1J5P NAD 0.0007875 0.41029 18.593
575 4Y2H 49K 0.0001141 0.49107 20.1005
576 4Y2H SAH 0.0001162 0.49072 20.1005
577 5GM1 SAH 0.001686 0.41994 21.608
578 5DX0 SFG 0.00004287 0.48868 23.1156
579 5DWQ SFG 0.00007641 0.47645 23.1156
580 5DX8 SFG 0.0001376 0.46408 23.1156
581 5DXA SFG 0.0001756 0.45978 23.1156
582 5DX1 SFG 0.0001701 0.44671 23.1156
583 1Z3C SA8 0.0004668 0.45265 24.6231
584 5THY SAH 0.00009854 0.47883 26.1307
585 3CBG SAH 0.00001007 0.53815 27.1357
586 3ABI NAD 0.0004987 0.4112 27.1357
587 5E8J SAH 0.000252 0.48581 27.2727
588 4JJF FE9 0.0007803 0.4116 27.6382
589 5THZ SAH 0.0001755 0.45979 28.1407
590 5JGL SAM 0.008018 0.40793 38.6935
Pocket No.: 2; Query (leader) PDB : 1P1C; Ligand: SAH; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1p1c.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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