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Receptor
PDB id Resolution Class Description Source Keywords
1OVD 2.25 Å EC: 1.3.98.1 THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDR IN COMPLEX WITH OROTATE LACTOCOCCUS LACTIS HOMODIMER ALPHA-BETA BARREL FLAVOPROTEIN OROTATE COMPLEXENZYME OXIDOREDUCTASE
Ref.: LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A M REVEAL IMPORTANT FACETS OF THE ENZYMATIC FUNCTION. J.BIOL.CHEM. V. 278 28812 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FMN A:800;
B:801;
 Valid;
Valid;
 none;
none;
 submit data
456.344 C17 H21 N4 O9 P Cc1cc...
GOL A:492;
A:493;
A:495;
B:491;
B:494;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
MG A:850;
B:851;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
24.305 Mg [Mg+2...
ORO A:900;
B:901;
 Valid;
Valid;
 none;
none;
 Kd = 7.6 uM
156.096 C5 H4 N2 O4 C1=C(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1OVD 2.25 Å EC: 1.3.98.1 THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDR IN COMPLEX WITH OROTATE LACTOCOCCUS LACTIS HOMODIMER ALPHA-BETA BARREL FLAVOPROTEIN OROTATE COMPLEXENZYME OXIDOREDUCTASE
Ref.: LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A M REVEAL IMPORTANT FACETS OF THE ENZYMATIC FUNCTION. J.BIOL.CHEM. V. 278 28812 2003
Members (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1JQX Kd = 95 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
2 1JQV Kd = 117 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
3 2DOR - ORO C5 H4 N2 O4 C1=C(NC(=O....
4 1DOR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
5 1JRB Kd = 1450 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
6 1JUE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
7 1OVD Kd = 7.6 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
8 1JRC Kd = 44 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
9 2BX7 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
10 2BSL Kd = 8 uM DHB C7 H6 O4 c1cc(c(cc1....
11 1JUB - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
70% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3C3N - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 2E6D - FUM C4 H4 O4 C(=C/C(=O)....
3 4WZH - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 1JQX Kd = 95 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
5 1JQV Kd = 117 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
6 2DOR - ORO C5 H4 N2 O4 C1=C(NC(=O....
7 1DOR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
8 1JRB Kd = 1450 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
9 1JUE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
10 1OVD Kd = 7.6 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
11 1JRC Kd = 44 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
12 2BX7 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
13 2BSL Kd = 8 uM DHB C7 H6 O4 c1cc(c(cc1....
14 1JUB - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
15 4EF8 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
16 3MJY Ki = 82.8 uM IJZ C5 H5 N3 O4 C1(=C(NC(=....
17 4EF9 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
18 3MHU Ki = 212.93 uM EJZ C5 H3 N3 O6 C1(=C(NC(=....
19 3TQ0 - FUM C4 H4 O4 C(=C/C(=O)....
20 2B4G - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
21 5XFV Kd = 0.000000012 uM FMN C17 H21 N4 O9 P Cc1cc2c(cc....
50% Homology Family (22)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3C3N - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 2E6D - FUM C4 H4 O4 C(=C/C(=O)....
3 4WZH - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 1JQX Kd = 95 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
5 1JQV Kd = 117 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
6 2DOR - ORO C5 H4 N2 O4 C1=C(NC(=O....
7 1DOR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
8 1JRB Kd = 1450 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
9 1JUE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
10 1OVD Kd = 7.6 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
11 1JRC Kd = 44 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
12 2BX7 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
13 2BSL Kd = 8 uM DHB C7 H6 O4 c1cc(c(cc1....
14 1JUB - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
15 4EF8 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
16 3MJY Ki = 82.8 uM IJZ C5 H5 N3 O4 C1(=C(NC(=....
17 4EF9 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
18 3MHU Ki = 212.93 uM EJZ C5 H3 N3 O6 C1(=C(NC(=....
19 3TQ0 - FUM C4 H4 O4 C(=C/C(=O)....
20 2B4G - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
21 5XFV Kd = 0.000000012 uM FMN C17 H21 N4 O9 P Cc1cc2c(cc....
22 3OIX - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FMN; Similar ligands found: 15
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAD 0.543307 0.876543
5 FAS 0.543307 0.876543
6 FAE 0.539062 0.865854
7 LFN 0.475 0.643836
8 C3F 0.473684 0.74359
9 CF4 0.463918 0.734177
10 FAY 0.446043 0.864198
11 FNR 0.444444 0.909091
12 RFL 0.442857 0.845238
13 4LS 0.411215 0.875
14 1VY 0.406593 0.769231
15 DLZ 0.404494 0.782051
Ligand no: 2; Ligand: ORO; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 ORO 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1OVD; Ligand: FMN; Similar sites found with APoc: 277
This union binding pocket(no: 1) in the query (biounit: 1ovd.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5WHU SIA GAL GLC None
2 5WHU SIA None
3 5V3D FCN None
4 4EZW ASN ARG LEU LEU LEU THR GLY 0.913242
5 1VHN FMN 1.60772
6 4TMC FMN 1.60772
7 4M5P FMN 1.60772
8 4TMC HBA 1.60772
9 2H8Z FMN 1.60772
10 2H8Z 8CM 1.60772
11 1SO0 GAL 1.60772
12 4ZJS 4P0 1.73913
13 1OJ4 ANP 1.76678
14 4K7O EKZ 1.78571
15 3TAO PGH 1.87266
16 3W9Z FMN 1.92926
17 5A1S FLC 1.92926
18 5C9P FUC 1.92926
19 4D52 GXL 1.92926
20 6BXL SAM 1.92926
21 1TZJ A3B 1.92926
22 3RE4 TO1 1.93798
23 3RET SAL 1.9802
24 3RET PYR 1.9802
25 1QPR PPC 2.11268
26 5TZO 7V7 2.12766
27 3T4L ZEA 2.22222
28 5IFK HPA 2.24359
29 3HF3 FMN 2.2508
30 1OYB FMN 2.2508
31 1OYB HBA 2.2508
32 2UXR ICT 2.2508
33 3ZSN MIV 2.2508
34 3VGL ANP 2.2508
35 2EFX NFA 2.2508
36 6APL C5P 2.2508
37 3CL5 SIO 2.2508
38 1C3X 8IG 2.25564
39 3EXS 5RP 2.26244
40 2FLI DX5 2.27273
41 4I9A NCN 2.43056
42 1D1Q 4NP 2.48447
43 5AJU RP5 2.55474
44 1PS9 FMN 2.57235
45 1ZFJ IMP 2.57235
46 2JG1 ANP 2.57235
47 2J5B TYE 2.57235
48 5YBL AKG 2.57235
49 5XIO ANP 2.57235
50 4U44 3D9 2.57235
51 3K7S R52 2.7933
52 1TRD PGH 2.8
53 4UP4 NDG 2.89389
54 4UP4 NAG 2.89389
55 1S20 TLA 2.89389
56 5L7V GNL 2.89389
57 2WW4 ADP 2.89389
58 3PGU OLA 2.89389
59 2VSU V55 2.90909
60 3N9R TD3 2.9316
61 5ZCT ANP 2.94118
62 2FJK 13P 2.95082
63 5KBE IPH 3.05677
64 1FDJ 13P 3.21543
65 1ICP FMN 3.21543
66 4PPF FLC 3.21543
67 5Y79 3PG 3.21543
68 2G50 PYR 3.21543
69 2GOU FMN 3.21543
70 5CKW ANP 3.21543
71 5UGH 8AJ 3.21543
72 3AB4 THR 3.37079
73 2V2G BEZ 3.43348
74 5JBX MLI 3.44828
75 6BFG FMN 3.53698
76 4A3U FMN 3.53698
77 1P4C FMN 3.53698
78 1XF1 CIT 3.53698
79 4V15 PLP 3.53698
80 1CT9 AMP 3.53698
81 3WCS MAN NAG 3.54331
82 3WCS MAN NAG GAL 3.54331
83 4YMZ 13P 3.58566
84 2YIP YIO 3.62319
85 1SW0 PGA 3.62903
86 5AHN IMP 3.68098
87 5GVR LMR 3.84615
88 5ZI9 FLC 3.84615
89 5N0O SAM 3.85852
90 1ONX ASP 3.85852
91 6FBA D48 3.85852
92 3LJU IP9 3.85852
93 1YBQ BDH 3.85852
94 4U60 SIA GAL NGA 3.92857
95 1VMK GUN 3.97112
96 5EYW PGA 4.01606
97 2YPI PGA 4.04858
98 5LU5 M7P 4.06091
99 6BKA FMN 4.18006
100 3ATY FMN 4.18006
101 2R14 FMN 4.18006
102 2R14 TXD 4.18006
103 1KAH HIS 4.18006
104 4K91 SIN 4.18006
105 1Z82 G3H 4.18006
106 2QPU QPS 4.18006
107 3TG5 SAH 4.18006
108 5YSQ INS 4.1958
109 4YGF AZM 4.2735
110 5AHM IMP 4.5
111 1Z42 FMN 4.50161
112 1Z44 FMN 4.50161
113 1Z41 FMN 4.50161
114 1Z48 FMN 4.50161
115 4QNW FMN 4.50161
116 4JIQ FMN 4.50161
117 4JIQ 1L5 4.50161
118 6F90 MVL 4.50161
119 2OG2 MLI 4.50161
120 6H45 QEI 4.50161
121 4F06 PHB 4.50161
122 3AI3 SOE 4.56274
123 3B9Q MLI 4.63576
124 4RW3 IPD 4.63576
125 1LBZ FBP 4.7619
126 1BO4 COA 4.7619
127 1QDS PGA 4.78088
128 2HSA FMN 4.82315
129 5GVH FMN 4.82315
130 5CX6 CDP 4.82315
131 4WOE 3S5 4.82315
132 3P13 RIP 4.86111
133 2HHJ DG2 4.86891
134 2HHJ 3PG 4.86891
135 3KPB SAM 4.91803
136 3QH2 3NM 4.97738
137 2E0N SAH 5.01931
138 1XXA ARG 5.12821
139 3BW2 FMN 5.14469
140 2RDT FMN 5.14469
141 1VYP FMN 5.14469
142 2RDT 2RD 5.14469
143 1VYP TNF 5.14469
144 4A59 AMP 5.14469
145 4BHN BH9 5.14469
146 2BTM PGA 5.15873
147 2GMP NAG MAN 5.15873
148 4RYV ZEA 5.16129
149 4P8O 883 5.34759
150 4BI7 PGA 5.44747
151 2OEM 1AE 5.46624
152 4IXH IMP 5.46624
153 1GVF PGH 5.59441
154 3GCZ SAM 5.67376
155 4UTU LRY 5.67686
156 4UTW RFW 5.67686
157 2II3 CAO 5.72519
158 2BKX F6R 5.78512
159 1KBJ FMN 5.78778
160 1KBI FMN 5.78778
161 1KBI PYR 5.78778
162 2ZUX RAM 5.78778
163 1JCM 137 5.79151
164 2Y2B AH0 5.88235
165 2Q3O FMN 6.10932
166 2GJN FMN 6.10932
167 2GJN NIS 6.10932
168 5MB4 NDG 6.10932
169 1DJN FMN 6.10932
170 2F5X ASP 6.10932
171 4YRD 3IT 6.10932
172 2OL1 UMP 6.12245
173 3AXK NDP 6.20155
174 2RI1 GLP 6.38298
175 2AWN ADP 6.43087
176 1LYX PGA 6.45161
177 1NKI PPF 6.66667
178 2Q3R FMN 6.75241
179 4AF0 IMP 6.75241
180 5XXS COA 6.81818
181 1Q6O LG6 6.94444
182 1LPD ADE 7.08661
183 5MWE TCE 7.14286
184 1NE7 AGP 7.26644
185 4CW5 FMN 7.3955
186 2JFV FLC 7.56014
187 5TCI MLI 7.71704
188 1OFD AKG 7.71704
189 1OFD FMN 7.71704
190 2Z48 A2G 7.71704
191 2Z48 NGA 7.71704
192 3Q2K HP7 7.71704
193 5YRF GLC GLC 7.74648
194 3ZZH NLG 7.81759
195 4EWN 0VR 7.90514
196 4FFG 0U8 8.03859
197 3A75 GLU 8.03859
198 2JK0 ASP 8.03859
199 5YZ2 AMP 8.33333
200 5OCS FMN 8.36013
201 3KRU FMN 8.36013
202 2X5F PLP 8.36013
203 2RH1 CAU 8.36013
204 4JGT PYR 8.3612
205 6FWH 5LD 8.62944
206 4TQK NAG 8.68167
207 1W8S FBP 8.74525
208 3HGM ATP 8.84354
209 1APZ ASP 9.21986
210 2WCV FUC 9.28571
211 1XXR MAN 9.31677
212 6DVH FMN 9.32476
213 4JEJ 1GP 9.42623
214 4Q4K FMN 9.6463
215 1AL8 FMN 9.6463
216 1AL8 DHP 9.6463
217 1GQ2 OXL 9.6463
218 4NTM 2K8 9.91736
219 1VBJ CIT 9.96441
220 2NLI LAC 9.96785
221 2NLI FMN 9.96785
222 3HQP FDP 9.96785
223 2C6Q IMP 9.96785
224 5N9Z CAP 10.0719
225 2Z6I FMN 10.2894
226 4D00 SIA GAL NAG 10.2894
227 6MJF SAH 10.9325
228 2Z6J FMN 10.9325
229 5W6Y TRP 10.9325
230 5M45 AMP 10.9325
231 6G47 SIA 11.0048
232 5Y02 MXN 11.215
233 3OVR 5SP 11.4035
234 6BVE PGA 11.4286
235 1O9W NAG 11.8644
236 1TB3 FMN 11.8971
237 4YEE 4CQ 12.2222
238 4Q9N 0WE 12.4161
239 4XP7 FNR 12.5402
240 4IP7 FLC 12.5402
241 3CTL S6P 12.5541
242 4FGC PQ0 12.7273
243 2ZRU FMN 13.1833
244 1GPJ CIT 13.1833
245 4HBM 0Y7 13.3333
246 3B0P FMN 14.4695
247 5YRV 5AD 14.5985
248 3GLC R5P 14.9153
249 2F6U CIT 15.3846
250 1CM0 COA 15.4762
251 1NBU PH2 15.9664
252 1TV5 ORO 16.0772
253 1TV5 FMN 16.0772
254 4N02 FNR 16.0772
255 1M5W DXP 16.4609
256 5CSS G3P 16.8142
257 5ABX MGP 17.0732
258 1OGD RIP 19.8473
259 4NAE 1GP 20
260 4C1W SLT 21.2766
261 3IWD M2T 22.5806
262 2WQ4 SFU 26.9231
263 1F76 FMN 40.5145
264 1F76 ORO 40.5145
265 1GTE IUR 42.4437
266 1GTE FMN 42.4437
267 1UUO ORO 44.0514
268 1UUO FMN 44.0514
269 1UUO BRF 44.0514
270 4IGH ORO 45.6592
271 4IGH FMN 45.6592
272 4IGH 1EA 45.6592
273 1EP2 FMN 46.6238
274 1EP2 ORO 46.6238
275 4ORM ORO 47.91
276 4ORM 2V6 47.91
277 4ORM FMN 47.91
Pocket No.: 2; Query (leader) PDB : 1OVD; Ligand: FMN; Similar sites found with APoc: 122
This union binding pocket(no: 2) in the query (biounit: 1ovd.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 5O0Z 9GB None
2 2ZTG A5A 1.60772
3 4P6G 2FZ 1.76991
4 2OO0 PLP 1.92926
5 1C1D PHE 1.92926
6 4D52 GIV 1.92926
7 3UDG TMP 2.32558
8 6GSG RCO 2.57235
9 5DNK SAH 2.57235
10 4DA5 0H7 2.57235
11 4EES FMN 2.6087
12 3CYI ATP 2.72727
13 2WMI A2G GAL FUC 2.89389
14 3GAY P6T 2.89389
15 4JAW GAL NGT 2.89389
16 4AOA IK2 2.89389
17 2VSS V55 2.89855
18 3C56 PH4 2.9316
19 3SHR CMP 3.01003
20 3ITJ CIT 3.21543
21 4M1U A2G MBG 3.367
22 3GUZ PAF 3.40909
23 3OUM TOF 3.44828
24 2B4B COA 3.50877
25 2B4D COA 3.50877
26 5WZN A2G 3.53698
27 3WEC AUI 3.53698
28 1L5J TRA 3.53698
29 2V67 CAP 3.57143
30 2V6A CAP 3.57143
31 2V68 CAP 3.57143
32 2V63 CAP 3.57143
33 2VDH CAP 3.57143
34 1IR2 CAP 3.57143
35 1GK8 CAP 3.57143
36 3HY2 ATP 3.63636
37 5OCG 9R5 3.7037
38 1UZD CAP 3.73134
39 2QCD U5P 3.84615
40 3VKC FPQ 3.84615
41 4A2A ATP 3.85852
42 5NN6 MIG 3.85852
43 3E3U NVC 4.06091
44 4JLZ UTP 4.18006
45 5KJW 53C 4.18006
46 4ZCW 4NG 4.18006
47 4MJ0 SIA SIA GAL 4.36364
48 4MJ0 SIA SIA 4.36364
49 4MJ0 BGC SIA SIA GAL 4.36364
50 3D04 SAK 4.40252
51 5TED SKM 4.42478
52 4XFM THE 4.50161
53 5BO9 CSF 4.50161
54 1K0D GSH 4.61538
55 4C2G ALA ALA ALA ALA 4.82315
56 5TDF 7A3 4.82315
57 3UWV 2PG 4.82315
58 1Y13 BIO 4.97238
59 1N71 COA 5
60 1Y2F WAI 5.03597
61 1NJJ ORX 5.14469
62 2GN3 MMA 5.15873
63 2GNB MAN 5.15873
64 2GN3 MAN 5.15873
65 2JBH 5GP 5.33333
66 1BWV CAP 5.46624
67 5WXU FLC 5.46624
68 1TIQ COA 5.55556
69 5IM3 DTP 5.78778
70 4Z0G 5GP 5.78778
71 6HKE MLT 5.78778
72 1JQY A32 5.82524
73 3BP1 GUN 5.86207
74 3B6R CRN 6.10932
75 4DOE CBK 6.10932
76 4B9Z ACR 6.10932
77 3NZ1 3NY 6.13027
78 1SQL GUN 6.16438
79 5UIV ADP 6.1674
80 1WDD CAP 6.25
81 3LGS ADE 6.36704
82 1VKF CIT 6.38298
83 1UNQ 4IP 6.4
84 4HE2 AMP 6.50888
85 2HXW FLC 6.75105
86 2QX0 PH2 6.91824
87 1NX4 AKG 6.95971
88 4ZSI 4R1 7.01754
89 5GJO PLP 7.07396
90 1IR1 CAP 7.31707
91 1OX5 1PR 7.3955
92 3DGB MUC 7.3955
93 3KP6 SAL 7.94702
94 5W75 SUC 8.03859
95 4TR9 38D 8.03859
96 4TR9 ASP TRP ASN 8.03859
97 1PVN MZP 8.7766
98 1UJP CIT 9.22509
99 5A0U CHT 9.6463
100 5JPH COA 9.72222
101 2R0H CTO 9.7561
102 4NTK ZSP 9.91736
103 3HQP OXL 9.96785
104 1PTR PRB 10
105 3KCC CMP 10
106 2C49 ADN 10.9272
107 1L5Y BEF 10.9677
108 4TWL ASC 11.7886
109 2PAR TMP 11.9403
110 5OYA CAP 12.2302
111 1UZH CAP 12.2951
112 4NSQ COA 13.1579
113 4Z2S NDG 13.3803
114 4Z2S NAG 13.3803
115 1RBL CAP 14.6789
116 2XSB GDL 15.7556
117 3CR3 ADP 19.8347
118 2HK9 ATR 20.3636
119 5YRI GLC GLC 21.1268
120 3S0E EOL 23.5294
121 4PSW COA 23.6842
122 6FA4 D1W 26.0116
Pocket No.: 3; Query (leader) PDB : 1OVD; Ligand: ORO; Similar sites found with APoc: 334
This union binding pocket(no: 3) in the query (biounit: 1ovd.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 5O0Z 9GB None
2 5WHU SIA GAL GLC None
3 5WHU SIA None
4 4EZW ASN ARG LEU LEU LEU THR GLY 0.913242
5 1VHN FMN 1.60772
6 4TMC FMN 1.60772
7 4M5P FMN 1.60772
8 4TMC HBA 1.60772
9 2H8Z 8CM 1.60772
10 2H8Z FMN 1.60772
11 2ZTG A5A 1.60772
12 4ZJS 4P0 1.73913
13 1OJ4 ANP 1.76678
14 4P6G 2FZ 1.76991
15 4K7O EKZ 1.78571
16 3TAO PGH 1.87266
17 3W9Z FMN 1.92926
18 5C9P FUC 1.92926
19 2OO0 PLP 1.92926
20 1C1D PHE 1.92926
21 4D52 GIV 1.92926
22 4D52 GXL 1.92926
23 6BXL SAM 1.92926
24 3RET SAL 1.9802
25 3RET PYR 1.9802
26 1QPR PPC 2.11268
27 5TZO 7V7 2.12766
28 3HF3 FMN 2.2508
29 1OYB FMN 2.2508
30 1OYB HBA 2.2508
31 3ZSN MIV 2.2508
32 3CL5 SIO 2.2508
33 3EXS 5RP 2.26244
34 2FLI DX5 2.27273
35 3UDG TMP 2.32558
36 4I9A NCN 2.43056
37 1D1Q 4NP 2.48447
38 5AJU RP5 2.55474
39 1PS9 FMN 2.57235
40 1ZFJ IMP 2.57235
41 6GSG RCO 2.57235
42 5YBL AKG 2.57235
43 5DNK SAH 2.57235
44 4DA5 0H7 2.57235
45 5XIO ANP 2.57235
46 4EES FMN 2.6087
47 3CYI ATP 2.72727
48 3K7S R52 2.7933
49 1TRD PGH 2.8
50 4UP4 NAG 2.89389
51 4UP4 NDG 2.89389
52 2WMI A2G GAL FUC 2.89389
53 3GAY P6T 2.89389
54 1S20 TLA 2.89389
55 4JAW GAL NGT 2.89389
56 4AOA IK2 2.89389
57 3PGU OLA 2.89389
58 2WW4 ADP 2.89389
59 2VSS V55 2.89855
60 3N9R TD3 2.9316
61 3C56 PH4 2.9316
62 2FJK 13P 2.95082
63 3SHR CMP 3.01003
64 5KBE IPH 3.05677
65 1ICP FMN 3.21543
66 1FDJ 13P 3.21543
67 4PPF FLC 3.21543
68 2GOU FMN 3.21543
69 3ITJ CIT 3.21543
70 2G50 PYR 3.21543
71 5CKW ANP 3.21543
72 5UGH 8AJ 3.21543
73 4M1U A2G MBG 3.367
74 3GUZ PAF 3.40909
75 2V2G BEZ 3.43348
76 5JBX MLI 3.44828
77 3OUM TOF 3.44828
78 2B4B COA 3.50877
79 2B4D COA 3.50877
80 4A3U FMN 3.53698
81 6BFG FMN 3.53698
82 1P4C FMN 3.53698
83 5WZN A2G 3.53698
84 3WEC AUI 3.53698
85 1L5J TRA 3.53698
86 4V15 PLP 3.53698
87 1XF1 CIT 3.53698
88 1CT9 AMP 3.53698
89 3WCS MAN NAG 3.54331
90 3WCS MAN NAG GAL 3.54331
91 2V67 CAP 3.57143
92 2V6A CAP 3.57143
93 2V68 CAP 3.57143
94 2V63 CAP 3.57143
95 2VDH CAP 3.57143
96 1IR2 CAP 3.57143
97 1GK8 CAP 3.57143
98 4YMZ 13P 3.58566
99 1SW0 PGA 3.62903
100 3HY2 ATP 3.63636
101 5AHN IMP 3.68098
102 5OCG 9R5 3.7037
103 1UZD CAP 3.73134
104 5GVR LMR 3.84615
105 2QCD U5P 3.84615
106 3VKC FPQ 3.84615
107 5N0O SAM 3.85852
108 4A2A ATP 3.85852
109 5NN6 MIG 3.85852
110 1YBQ BDH 3.85852
111 5EYW PGA 4.01606
112 2YPI PGA 4.04858
113 3E3U NVC 4.06091
114 5LU5 M7P 4.06091
115 6BKA FMN 4.18006
116 3ATY FMN 4.18006
117 2R14 FMN 4.18006
118 4JLZ UTP 4.18006
119 2R14 TXD 4.18006
120 5KJW 53C 4.18006
121 4K91 SIN 4.18006
122 4ZCW 4NG 4.18006
123 5YSQ INS 4.1958
124 4MJ0 SIA SIA GAL 4.36364
125 4MJ0 SIA SIA 4.36364
126 4MJ0 BGC SIA SIA GAL 4.36364
127 3D04 SAK 4.40252
128 5TED SKM 4.42478
129 5AHM IMP 4.5
130 1Z44 FMN 4.50161
131 1Z48 FMN 4.50161
132 1Z42 FMN 4.50161
133 1Z41 FMN 4.50161
134 4QNW FMN 4.50161
135 4JIQ FMN 4.50161
136 4JIQ 1L5 4.50161
137 4XFM THE 4.50161
138 6F90 MVL 4.50161
139 2OG2 MLI 4.50161
140 6H45 QEI 4.50161
141 5BO9 CSF 4.50161
142 3AI3 SOE 4.56274
143 1K0D GSH 4.61538
144 4RW3 IPD 4.63576
145 1BO4 COA 4.7619
146 1LBZ FBP 4.7619
147 1QDS PGA 4.78088
148 2HSA FMN 4.82315
149 5GVH FMN 4.82315
150 4C2G ALA ALA ALA ALA 4.82315
151 5CX6 CDP 4.82315
152 5TDF 7A3 4.82315
153 3UWV 2PG 4.82315
154 3P13 RIP 4.86111
155 2HHJ DG2 4.86891
156 2HHJ 3PG 4.86891
157 1Y13 BIO 4.97238
158 3QH2 3NM 4.97738
159 1N71 COA 5
160 1Y2F WAI 5.03597
161 3BW2 FMN 5.14469
162 2RDT FMN 5.14469
163 1VYP FMN 5.14469
164 1VYP TNF 5.14469
165 2RDT 2RD 5.14469
166 4A59 AMP 5.14469
167 1NJJ ORX 5.14469
168 2BTM PGA 5.15873
169 2GMP NAG MAN 5.15873
170 2GN3 MMA 5.15873
171 2GNB MAN 5.15873
172 2GN3 MAN 5.15873
173 2JBH 5GP 5.33333
174 4P8O 883 5.34759
175 4BI7 PGA 5.44747
176 2OEM 1AE 5.46624
177 4IXH IMP 5.46624
178 1BWV CAP 5.46624
179 5WXU FLC 5.46624
180 1TIQ COA 5.55556
181 1GVF PGH 5.59441
182 4UTU LRY 5.67686
183 4UTW RFW 5.67686
184 2II3 CAO 5.72519
185 2BKX F6R 5.78512
186 1KBJ FMN 5.78778
187 1KBI PYR 5.78778
188 1KBI FMN 5.78778
189 5IM3 DTP 5.78778
190 4Z0G 5GP 5.78778
191 6HKE MLT 5.78778
192 1JCM 137 5.79151
193 1JQY A32 5.82524
194 3BP1 GUN 5.86207
195 2Y2B AH0 5.88235
196 2Q3O FMN 6.10932
197 2GJN FMN 6.10932
198 2GJN NIS 6.10932
199 1DJN FMN 6.10932
200 3B6R CRN 6.10932
201 5MB4 NDG 6.10932
202 2F5X ASP 6.10932
203 4DOE CBK 6.10932
204 4B9Z ACR 6.10932
205 2OL1 UMP 6.12245
206 3NZ1 3NY 6.13027
207 1SQL GUN 6.16438
208 5UIV ADP 6.1674
209 3AXK NDP 6.20155
210 1WDD CAP 6.25
211 3LGS ADE 6.36704
212 2RI1 GLP 6.38298
213 1VKF CIT 6.38298
214 1UNQ 4IP 6.4
215 1LYX PGA 6.45161
216 4HE2 AMP 6.50888
217 2HXW FLC 6.75105
218 2Q3R FMN 6.75241
219 4AF0 IMP 6.75241
220 5XXS COA 6.81818
221 2QX0 PH2 6.91824
222 1Q6O LG6 6.94444
223 1NX4 AKG 6.95971
224 4ZSI 4R1 7.01754
225 5GJO PLP 7.07396
226 1NE7 AGP 7.26644
227 1IR1 CAP 7.31707
228 4CW5 FMN 7.3955
229 1OX5 1PR 7.3955
230 3DGB MUC 7.3955
231 2JFV FLC 7.56014
232 5TCI MLI 7.71704
233 1OFD AKG 7.71704
234 1OFD FMN 7.71704
235 2Z48 A2G 7.71704
236 3ZZH NLG 7.81759
237 4EWN 0VR 7.90514
238 3KP6 SAL 7.94702
239 4FFG 0U8 8.03859
240 3A75 GLU 8.03859
241 5W75 SUC 8.03859
242 4TR9 38D 8.03859
243 4TR9 ASP TRP ASN 8.03859
244 5OCS FMN 8.36013
245 3KRU FMN 8.36013
246 2X5F PLP 8.36013
247 2RH1 CAU 8.36013
248 4TQK NAG 8.68167
249 1W8S FBP 8.74525
250 1PVN MZP 8.7766
251 1APZ ASP 9.21986
252 1UJP CIT 9.22509
253 2WCV FUC 9.28571
254 6DVH FMN 9.32476
255 4JEJ 1GP 9.42623
256 4Q4K FMN 9.6463
257 1AL8 FMN 9.6463
258 1AL8 DHP 9.6463
259 5A0U CHT 9.6463
260 5JPH COA 9.72222
261 2R0H CTO 9.7561
262 4NTK ZSP 9.91736
263 2NLI FMN 9.96785
264 2NLI LAC 9.96785
265 2C6Q IMP 9.96785
266 3HQP OXL 9.96785
267 3HQP FDP 9.96785
268 1PTR PRB 10
269 3KCC CMP 10
270 5N9Z CAP 10.0719
271 2Z6I FMN 10.2894
272 4D00 SIA GAL NAG 10.2894
273 2C49 ADN 10.9272
274 6MJF SAH 10.9325
275 2Z6J FMN 10.9325
276 5M45 AMP 10.9325
277 1L5Y BEF 10.9677
278 6G47 SIA 11.0048
279 5Y02 MXN 11.215
280 3OVR 5SP 11.4035
281 6BVE PGA 11.4286
282 4TWL ASC 11.7886
283 1TB3 FMN 11.8971
284 2PAR TMP 11.9403
285 4YEE 4CQ 12.2222
286 5OYA CAP 12.2302
287 1UZH CAP 12.2951
288 4XP7 FNR 12.5402
289 4IP7 FLC 12.5402
290 3CTL S6P 12.5541
291 4FGC PQ0 12.7273
292 4NSQ COA 13.1579
293 2ZRU FMN 13.1833
294 1GPJ CIT 13.1833
295 4HBM 0Y7 13.3333
296 4Z2S NAG 13.3803
297 4Z2S NDG 13.3803
298 3B0P FMN 14.4695
299 1RBL CAP 14.6789
300 3GLC R5P 14.9153
301 2F6U CIT 15.3846
302 2XSB GDL 15.7556
303 1NBU PH2 15.9664
304 1TV5 FMN 16.0772
305 1TV5 ORO 16.0772
306 4N02 FNR 16.0772
307 1M5W DXP 16.4609
308 5CSS G3P 16.8142
309 3CR3 ADP 19.8347
310 1OGD RIP 19.8473
311 4NAE 1GP 20
312 2HK9 ATR 20.3636
313 5YRI GLC GLC 21.1268
314 4C1W SLT 21.2766
315 3IWD M2T 22.5806
316 3S0E EOL 23.5294
317 4PSW COA 23.6842
318 6FA4 D1W 26.0116
319 2WQ4 SFU 26.9231
320 1F76 FMN 40.5145
321 1F76 ORO 40.5145
322 1GTE IUR 42.4437
323 1GTE FMN 42.4437
324 1UUO ORO 44.0514
325 1UUO FMN 44.0514
326 1UUO BRF 44.0514
327 4IGH 1EA 45.6592
328 4IGH FMN 45.6592
329 4IGH ORO 45.6592
330 1EP2 FMN 46.6238
331 1EP2 ORO 46.6238
332 4ORM ORO 47.91
333 4ORM 2V6 47.91
334 4ORM FMN 47.91
Pocket No.: 4; Query (leader) PDB : 1OVD; Ligand: ORO; Similar sites found with APoc: 65
This union binding pocket(no: 4) in the query (biounit: 1ovd.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5V3D FCN None
2 1SO0 GAL 1.60772
3 5A1S FLC 1.92926
4 1TZJ A3B 1.92926
5 3RE4 TO1 1.93798
6 3T4L ZEA 2.22222
7 5IFK HPA 2.24359
8 2UXR ICT 2.2508
9 3VGL ANP 2.2508
10 2EFX NFA 2.2508
11 6APL C5P 2.2508
12 1C3X 8IG 2.25564
13 2JG1 ANP 2.57235
14 2J5B TYE 2.57235
15 4U44 3D9 2.57235
16 5L7V GNL 2.89389
17 2VSU V55 2.90909
18 5ZCT ANP 2.94118
19 5Y79 3PG 3.21543
20 3AB4 THR 3.37079
21 2YIP YIO 3.62319
22 5ZI9 FLC 3.84615
23 1ONX ASP 3.85852
24 6FBA D48 3.85852
25 3LJU IP9 3.85852
26 4U60 SIA GAL NGA 3.92857
27 1VMK GUN 3.97112
28 1KAH HIS 4.18006
29 1Z82 G3H 4.18006
30 2QPU QPS 4.18006
31 3TG5 SAH 4.18006
32 4YGF AZM 4.2735
33 4F06 PHB 4.50161
34 3B9Q MLI 4.63576
35 4WOE 3S5 4.82315
36 3KPB SAM 4.91803
37 2E0N SAH 5.01931
38 1XXA ARG 5.12821
39 4BHN BH9 5.14469
40 4RYV ZEA 5.16129
41 3GCZ SAM 5.67376
42 2ZUX RAM 5.78778
43 4YRD 3IT 6.10932
44 2AWN ADP 6.43087
45 1NKI PPF 6.66667
46 1LPD ADE 7.08661
47 5MWE TCE 7.14286
48 2Z48 NGA 7.71704
49 3Q2K HP7 7.71704
50 5YRF GLC GLC 7.74648
51 2JK0 ASP 8.03859
52 5YZ2 AMP 8.33333
53 4JGT PYR 8.3612
54 6FWH 5LD 8.62944
55 3HGM ATP 8.84354
56 1XXR MAN 9.31677
57 1GQ2 OXL 9.6463
58 4NTM 2K8 9.91736
59 1VBJ CIT 9.96441
60 5W6Y TRP 10.9325
61 1O9W NAG 11.8644
62 4Q9N 0WE 12.4161
63 5YRV 5AD 14.5985
64 1CM0 COA 15.4762
65 5ABX MGP 17.0732
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