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Receptor
PDB id Resolution Class Description Source Keywords
1OE0 2.4 Å EC: 2.7.1.145 CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP DROSOPHILA MELANOGASTER TRANSFERASE DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE DTTP COMPLEX FEEDBACK INHIBITION SALVAGE PATHWAY
Ref.: STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF THE DEOXYRIBONUCLEOSIDE SALVAGE PATHWAY:STUDIES OF THE DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE BIOCHEMISTRY V. 42 5706 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:400;
B:400;
C:400;
D:400;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
TTP A:300;
B:300;
C:300;
D:300;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Ki = 5.3 nM
482.168 C10 H17 N2 O14 P3 CC1=C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1OE0 2.4 Å EC: 2.7.1.145 CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP DROSOPHILA MELANOGASTER TRANSFERASE DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE DTTP COMPLEX FEEDBACK INHIBITION SALVAGE PATHWAY
Ref.: STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF THE DEOXYRIBONUCLEOSIDE SALVAGE PATHWAY:STUDIES OF THE DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE BIOCHEMISTRY V. 42 5706 2003
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2VP5 - DCZ C9 H13 N3 O4 C1[C@@H]([....
2 2JCS - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
3 2VPP - GEO C9 H11 F2 N3 O4 C1=CN(C(=O....
4 2VP2 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
5 1ZM7 ic50 > 1000 uM TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
6 2VP0 - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
7 1OE0 Ki = 5.3 nM TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
8 1OT3 - THM C10 H14 N2 O5 CC1=CN(C(=....
9 2VP4 - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2VP5 - DCZ C9 H13 N3 O4 C1[C@@H]([....
2 2JCS - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
3 2VPP - GEO C9 H11 F2 N3 O4 C1=CN(C(=O....
4 2VP2 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
5 1ZM7 ic50 > 1000 uM TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
6 2VP0 - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
7 1OE0 Ki = 5.3 nM TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
8 1OT3 - THM C10 H14 N2 O5 CC1=CN(C(=....
9 2VP4 - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2VP5 - DCZ C9 H13 N3 O4 C1[C@@H]([....
2 2JCS - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
3 2VPP - GEO C9 H11 F2 N3 O4 C1=CN(C(=O....
4 2VP2 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
5 1ZM7 ic50 > 1000 uM TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
6 2VP0 - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
7 1OE0 Ki = 5.3 nM TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
8 1OT3 - THM C10 H14 N2 O5 CC1=CN(C(=....
9 2VP4 - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: TTP; Similar ligands found: 79
No: Ligand ECFP6 Tc MDL keys Tc
1 TTP 1 1
2 TYD 0.884058 1
3 TMP 0.760563 0.985714
4 TLO 0.722892 0.945205
5 DAU 0.701149 0.932432
6 TDX 0.689655 0.945205
7 18T 0.689655 0.932432
8 TRH 0.689655 0.932432
9 3R2 0.689655 0.92
10 1JB 0.689655 0.932432
11 3YN 0.674157 0.932432
12 T3Q 0.674157 0.907895
13 DWN 0.674157 0.907895
14 T3F 0.674157 0.907895
15 0N2 0.666667 0.896104
16 T46 0.666667 0.932432
17 0FX 0.659341 0.907895
18 MMF 0.659341 0.907895
19 QDM 0.645161 0.896104
20 AKM 0.638298 0.886076
21 1YF 0.638298 0.92
22 JHZ 0.638298 0.884615
23 FNF 0.638298 0.92
24 4TG 0.631579 0.92
25 TBD 0.62963 0.958904
26 DUT 0.62963 0.957143
27 D3T 0.62963 0.971831
28 T5A 0.61165 0.841463
29 THM 0.605634 0.873239
30 LLT 0.605634 0.873239
31 ATY 0.6 0.945205
32 FUH 0.588235 0.907895
33 QUH 0.588235 0.907895
34 AZD 0.586207 0.907895
35 DT DT DT 0.571429 0.917808
36 UFP 0.56962 0.905405
37 0DN 0.567568 0.833333
38 DCP 0.55814 0.891892
39 5HU 0.54321 0.971831
40 BRU 0.54321 0.905405
41 DUD 0.542169 0.957143
42 DT DT DT DT DT 0.541667 0.945205
43 NYM 0.536585 0.958333
44 FDM 0.536585 0.918919
45 5IU 0.536585 0.905405
46 ABT 0.531915 0.884615
47 T3P 0.531646 0.943662
48 DT DT PST 0.530612 0.87013
49 THP 0.53012 0.971429
50 D4T 0.528736 0.928571
51 6U4 0.521277 0.848101
52 ATM 0.517241 0.894737
53 7SG 0.512605 0.864198
54 TQP 0.512605 0.864198
55 TXS 0.512195 0.789474
56 TPE 0.510204 0.894737
57 T5K 0.508333 0.853659
58 T4K 0.508333 0.853659
59 BVP 0.5 0.944444
60 T3S 0.5 0.789474
61 8DG 0.489583 0.829268
62 YYY 0.477273 0.891892
63 2DT 0.47561 0.957747
64 4TA 0.469565 0.807229
65 DT ME6 DT 0.468468 0.87013
66 D4D 0.449438 0.928571
67 AZZ 0.447059 0.779221
68 DU 0.447059 0.942857
69 UMP 0.447059 0.942857
70 DUP 0.430108 0.930556
71 ADS THS THS THS 0.429752 0.758621
72 UTP 0.428571 0.875
73 8DD 0.424242 0.8125
74 WMJ 0.42 0.761905
75 DDN 0.418605 0.942857
76 8GD 0.418367 0.829268
77 DGT 0.415842 0.759036
78 UC5 0.406593 0.943662
79 ID2 0.402439 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1OE0; Ligand: TTP; Similar sites found with APoc: 434
This union binding pocket(no: 1) in the query (biounit: 1oe0.bio1) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 2XRH NIO None
2 2NLQ GLY None
3 3W5J GDP 0.980392
4 2CJW GDP 1.04167
5 2WIC GNP 1.30435
6 1FP6 ADP 1.30435
7 2O66 FLC 1.48148
8 3A4M ADP 1.73913
9 4R98 GNH 1.73913
10 3JSX CC2 1.73913
11 3JSX FAD 1.73913
12 1AKY AP5 1.81818
13 4X8O AP5 1.86916
14 4QRH 0O2 1.90476
15 2RGX AP5 1.94175
16 2W58 ADP 1.9802
17 3T1O GDP 2.0202
18 5W7Q GDP 2.17391
19 4Z7X 3CX 2.17391
20 1FZQ GDP 2.20994
21 2J0V GDP 2.35849
22 4WGF HX2 2.43902
23 2CBZ ATP 2.6087
24 2Y65 ADP 2.6087
25 3TBK ANP 2.6087
26 3DKP ADP 2.6087
27 5M04 GDP 2.6087
28 4UZI IMD 2.6087
29 6H5E ANP 2.6087
30 3FWY ADP 2.6087
31 2WJG GDP 2.65957
32 1ZJ6 G3D 2.6738
33 2B8T THM 2.69058
34 1YZG GDP 2.7933
35 1G16 GDP 2.94118
36 2WJH GDP 3.01205
37 2WJH FLC 3.01205
38 1F6B GDP 3.0303
39 2WHX ADP 3.04348
40 1SQ5 ADP 3.04348
41 3BOS CDP 3.04348
42 3U6B GDP 3.04348
43 1LVK MNT BEF 3.04348
44 2HCJ GDP 3.04348
45 1XKV ATP 3.04348
46 5Y6N ADP 3.04348
47 5JBQ GDP 3.04348
48 1XMV ADP 3.04348
49 5H7K GDP 3.04348
50 4G5G GDP 3.04348
51 1D8T GDP 3.04348
52 4KBF AMP 3.04348
53 3U6K GDP 3.04348
54 2JLR ANP 3.04348
55 2DPY ADP 3.04348
56 3VRV YSD 3.04348
57 3B7G ANP 3.04348
58 1XP8 AGS 3.04348
59 2BVN GNP 3.04348
60 6B8B ADP 3.04348
61 1OYY AGS 3.04348
62 5Z69 AGS 3.04348
63 3Q9L ATP 3.04348
64 6G14 G4P 3.04348
65 5G3Y ADP 3.09735
66 4WOP CTP 3.11111
67 5BQ5 ADP BEF 3.1746
68 2X2T GAL NGA 3.26797
69 4E03 ADP 3.39806
70 2HT6 GDP 3.44828
71 1UKZ ADP 3.44828
72 1UKZ AMP 3.44828
73 5ZXD ATP 3.47826
74 2ZFI ADP 3.47826
75 3BFV ADP 3.47826
76 4J0Q GDP 3.47826
77 4QOS ADP 3.47826
78 5YLF BGC 3.47826
79 4IHQ ADP 3.47826
80 2ZR9 DTP 3.47826
81 4DCT GDP 3.47826
82 4NE2 SH2 3.47826
83 4WEI GLC GAL 3.47826
84 4NE2 ADP 3.47826
85 2QZ4 ADP 3.47826
86 4A4Z ANP 3.47826
87 2OM2 GDP 3.47826
88 1G41 ADP 3.47826
89 3VMG 9CA 3.47826
90 6CRK GDP 3.47826
91 3G5S GSH 3.47826
92 1FNN ADP 3.47826
93 2CHG ANP 3.53982
94 3PQC GDP 3.58974
95 1HE1 AF3 3.7037
96 1M7G AV2 3.79147
97 1M7G ADX 3.79147
98 1M7G ADP 3.79147
99 4P3Y GDP 3.84615
100 4B47 GDP 3.85675
101 4SGA ACE PRO ALA PRO PHE 3.8674
102 5GVR LMR 3.91304
103 2XT3 ADP 3.91304
104 2GDJ ANP 3.91304
105 3EWA ANP 3.91304
106 1KK1 GNP 3.91304
107 1DAR GDP 3.91304
108 5H4S RAM 3.91304
109 3ZFD ANP 3.91304
110 2FSH ANP 3.91304
111 5MZN ADP 3.91304
112 5W76 GDP 3.91304
113 5W75 GDP 3.91304
114 4IEE AGS 3.91304
115 4NON GDP 3.91304
116 2XAU ADP 3.91304
117 4ZG4 VO4 ADP 3.91304
118 5EXT ADP 3.91304
119 2EFE GNH 3.91304
120 1CR1 TTP 3.91304
121 4R43 GDP 3.91304
122 3FVQ ATP 3.91304
123 5W75 SUC 3.91304
124 5I0H ADP BEF 3.91304
125 6BSX GDP 3.93258
126 5Z54 0HZ 3.96476
127 5O74 GDP 4.06091
128 1QF9 C5P 4.12371
129 1QF9 ADP 4.12371
130 1QF9 ALF 4.12371
131 1B4P GPS 4.14747
132 5E95 GDP 4.16667
133 1XX6 ADP 4.18848
134 1CLU DBG 4.21687
135 2IYL GDP 4.22535
136 5KUT GDP 4.2328
137 2FH5 GTP 4.32432
138 2NCD ADP 4.34783
139 4WZ6 ATP 4.34783
140 2AWN ADP 4.34783
141 3DC4 ADP 4.34783
142 1R0X ATP 4.34783
143 5N69 ADP 4.34783
144 5LTJ ADP 4.34783
145 5LTJ BEF 4.34783
146 5XDR ADP 4.34783
147 3P4X ADP 4.34783
148 4PJ3 ANP 4.34783
149 1G3Q ADP 4.34783
150 1NY5 ADP 4.34783
151 5WC2 ADP 4.34783
152 1YAA MAE 4.34783
153 5OPM DTP 4.34783
154 4PC3 GDP 4.34783
155 5X40 ACP 4.34783
156 2RI1 GLP 4.34783
157 2Q2Y ADP 4.34783
158 2Q2Y MKR 4.34783
159 1QHG ATP 4.34783
160 2PZE ATP 4.36681
161 5UIV ADP 4.40529
162 1S8F GDP 4.51977
163 4RJD TFP 4.54545
164 4XSH GSP 4.56621
165 4MKF AP5 4.60829
166 1NN5 2DT 4.65116
167 1NN5 ANP 4.65116
168 3H86 AP5 4.6875
169 3DOE GTP 4.6875
170 1RRC ADP 4.78261
171 1GOJ ADP 4.78261
172 1G6H ADP 4.78261
173 1JI0 ATP 4.78261
174 2GKS ADP 4.78261
175 3NHB ADP 4.78261
176 2D2F ADP 4.78261
177 1SKQ GDP 4.78261
178 4KVA GTP 4.78261
179 1B7T ADP 4.78261
180 2J0W ASP 4.78261
181 1WDT GTP 4.78261
182 4XTR ADP 4.78261
183 2C9O ADP 4.78261
184 1D5C GDP 4.93827
185 1KK8 BEF ADP 5.03597
186 1S3G AP5 5.06912
187 1KO8 6PG 5.14286
188 1OFH ADP 5.17241
189 1BG2 ADP 5.21739
190 5U32 GDP 5.21739
191 4PX9 ADP 5.21739
192 2IS6 ADP 5.21739
193 4LC1 GDP 5.21739
194 4HSE ADP 5.21739
195 5IRN ADP 5.21739
196 4ZNL BEF ADP 5.21739
197 5L3V GDP 5.21739
198 1G7S GDP 5.21739
199 5AK0 8V1 5.21739
200 1UJ2 C5P 5.21739
201 1UJ2 ADP 5.21739
202 1K6M AGS 5.21739
203 3DEF GDP 5.21739
204 3A1S GDP 5.21739
205 3BER AMP 5.22088
206 4R2I ANP 5.2381
207 5G41 AP5 5.38117
208 2GCO GNP 5.47264
209 4DKX GDP 5.55556
210 2VVG ADP 5.65217
211 3B5J 12D 5.65217
212 5HCN GCP 5.65217
213 1MKY GDP 5.65217
214 3SFV GDP 5.65217
215 2CST MAE 5.65217
216 3E70 GDP 5.65217
217 5HPY GDP 5.65217
218 2FAH GDP 5.65217
219 3L1N PLM 5.6701
220 1LOJ URI 5.74713
221 3CPJ GDP 5.8296
222 5TPV TYD 5.88235
223 4D0N GDP 5.94595
224 1VHT BA3 5.9633
225 4TTQ ATP 6.04651
226 1LVG ADP 6.06061
227 4FRZ ADP 6.08696
228 4PPF FLC 6.08696
229 1YRB GDP 6.08696
230 3DZD ADP 6.08696
231 1G6O ADP 6.08696
232 1TQ4 GDP 6.08696
233 2BIF SIN 6.08696
234 5L3S G 6.08696
235 5L3W GDP 6.08696
236 2C91 TLA 6.08696
237 2BIF ANP 6.08696
238 4YDS ATP 6.14035
239 2A9K GDP 6.27803
240 1JJV ATP 6.31068
241 3GJ4 GDP 6.33484
242 3GJ7 GDP 6.33484
243 3GJ0 GDP 6.33484
244 3GJ3 GDP 6.33484
245 3GJ5 GDP 6.33484
246 3GJ8 GDP 6.33484
247 3FB4 AP5 6.48148
248 3CH5 GDP 6.48148
249 5XKT GNP 6.5
250 4U00 ADP 6.52174
251 4AG5 ADP 6.52174
252 1YQT ADP 6.52174
253 5FG3 GDP 6.52174
254 5YV5 ADP 6.52174
255 5YT0 GDP 6.52174
256 2CE7 ADP 6.52174
257 5M7P ADP 6.52174
258 1X6V ADP 6.52174
259 1RQH PYR 6.52174
260 1ZUI SKM 6.54762
261 3T5G GDP 6.57895
262 1GXU 2HP 6.59341
263 4OGQ 7PH 6.70391
264 2ZTS ADP 6.77291
265 4BQS K2Q 6.81818
266 4BQS ADP 6.81818
267 2OG2 MLI 6.95652
268 3B9Q MLI 6.95652
269 2PL3 ADP 6.95652
270 1QXA GLY GLY GLY 6.95652
271 4BFW ZVW 6.95652
272 3IO3 ADP 6.95652
273 5IFS ADP 6.95652
274 4LYA ATP 6.95652
275 1Q19 SSC 6.95652
276 6FAA ADP 6.95652
277 1Y63 ADP 7.06522
278 5OEC GDP 7.10383
279 1Z83 AP5 7.14286
280 3KTA AP5 7.14286
281 2VPY PCI 7.17949
282 1MR3 G3D 7.18232
283 2OFW ADX 7.21154
284 3IIJ ADP 7.22222
285 2PEZ DAT 7.26257
286 2PEZ GGZ 7.26257
287 1R4A GNP 7.27273
288 1RYH GNP 7.38916
289 3LRE ADP 7.3913
290 1V8K ANP 7.3913
291 1OXV ANP 7.3913
292 5W97 CHD 7.3913
293 6B4K ANP 7.3913
294 3DTU DXC 7.3913
295 5Z84 CHD 7.3913
296 5ZCO CHD 7.3913
297 5CIC 51R 7.40741
298 3P2H MTA 7.46269
299 2ZX2 RAM 7.69231
300 1F9V ADP 7.82609
301 1U0J ADP 7.82609
302 1VKJ A3P 7.82609
303 5BXQ GDP 7.87402
304 3UIE ANP 8
305 5AMH EF2 8
306 1UPT GTP 8.18713
307 4LPS GDP 8.26087
308 5LLB 6YZ 8.26087
309 1I4D GDP 8.26087
310 1R6B ADP 8.26087
311 1OW3 GDP 8.26087
312 1IHU ADP 8.26087
313 4MKG AP5 8.29493
314 2HF9 GSP 8.40708
315 4HI0 GDP 8.54271
316 1W7J ADP BEF 8.60927
317 6A20 ADP 8.69565
318 5M8T 0TR 8.69565
319 4YS0 ADP 8.69565
320 2IXE ATP 8.69565
321 3Q85 GNP 8.87574
322 4CVN ADP 8.90052
323 5LB3 ADP 9.13043
324 5BN3 ADP 9.13043
325 2RCN GDP 9.13043
326 5KSZ GCP 9.13043
327 1Z6T ADP 9.13043
328 3TKY N7I 9.13043
329 2CK3 ANP 9.13043
330 5ZQ4 AMP 9.13043
331 1W0J ADP 9.13043
332 1W0J ADP BEF 9.13043
333 5TB5 GDP 9.18919
334 5TAR GDP 9.18919
335 3TMK T5A 9.25926
336 1OIV GDP 9.42408
337 1B0U ATP 9.54198
338 4YMU ATP 9.56522
339 3MD0 GDP 9.56522
340 1P72 ADP 9.56522
341 1P72 THM 9.56522
342 5ZBR ANP 9.56522
343 1D2E GDP 9.56522
344 4G86 BNT 9.56522
345 3EZ2 ADP 9.56522
346 2ORV 4TA 9.56522
347 2G77 AF3 9.59596
348 2G77 GDP 9.59596
349 1KI6 AHU 10
350 5KSP GDP 10
351 1E2K TMC 10
352 1DS6 GDP 10
353 5JCZ GDP 10.0559
354 1VG0 GDP 10.1449
355 3Q72 GNP 10.241
356 1T5C ADP 10.4348
357 5MVR ADP 10.4938
358 3WY9 GDP 10.8696
359 3WYA GDP 10.8696
360 2KIN ADP 11
361 5FTB ANP 11.3043
362 2ZE7 DST 11.3043
363 5VHC BEF ADP 11.3043
364 5FHD ADP ALF 11.3043
365 1VG1 GDP 11.3514
366 1VG9 GDP 11.3514
367 4DID GDP 11.399
368 2NGR GDP 11.5183
369 2NGR AF3 11.5183
370 1GRN AF3 11.5183
371 1A4R GNH 11.5183
372 1A4R GDP 11.5183
373 1GRN GDP 11.5183
374 2WMO GTP 11.5789
375 3COB ADP 11.7391
376 5IRC GDP 11.9403
377 3AQ4 GDP 11.9565
378 3LXR GDP 11.9792
379 1HTW ADP 12.0253
380 2A5J GDP 12.5654
381 3TK1 GDP 12.6087
382 1Z0A GDP 12.6437
383 5H7J GCP 13.0435
384 2QG6 NMN 13.0653
385 1O3Y GTP 13.253
386 1J2J GTP 13.253
387 2J59 GTP 13.253
388 3H4S ADP 13.3333
389 1RE0 GDP 13.4146
390 1S9D GDP 13.4146
391 6C90 ADP 13.4615
392 2VB6 ADP BEF 13.4783
393 4PFO ADP 13.4783
394 1KY3 GDP 13.7363
395 4YLG GDP 13.8728
396 3CNL GNP 13.913
397 2W83 GTP 13.9394
398 3N5C GDP 14.1975
399 4KFU ACP 14.6226
400 5TSH ADP 14.7826
401 5TSH ANP 14.7826
402 2D7D ADP 15
403 2QN6 GDP 15.0538
404 2X77 GDP 15.3439
405 3K4Z XGP 15.6522
406 2W2X GSP 16.129
407 2YOH WMJ 16.1905
408 3G4Q MCH 17.1233
409 5CK5 GDP 17.3913
410 5WLB GNP 17.6471
411 3QF7 ANP 18
412 5ZB0 TYD 18.1818
413 5ZB0 ADP 18.1818
414 3ZJQ NCA 18.4615
415 2CXG GLC GLC 18.6957
416 4QM7 GTP 19.2982
417 1ZIN AP5 19.3548
418 1JJ7 ADP 19.5652
419 4NU0 AP5 20.2765
420 3WIR BGC 21.7391
421 2CDN ADP 22.3881
422 2V7Q ADP 22.7273
423 2V7Q ATP 22.7273
424 5KDO GDP 24.3243
425 1SVI GDP 25.641
426 1PUJ GNP 26.087
427 1Z0F GDP 26.8156
428 5GOE GDP 27.3913
429 3ZIA ADP 28.5714
430 3ZIA ATP 28.5714
431 2Y69 CHD 28.5714
432 4TMK T5A 30.5164
433 2V54 TYD 33.3333
434 2JAQ DCP 45.8537
Pocket No.: 2; Query (leader) PDB : 1OE0; Ligand: TTP; Similar sites found with APoc: 9
This union binding pocket(no: 2) in the query (biounit: 1oe0.bio1) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 5Y02 MXN None
2 5JCP GDP ALF 1.73913
3 1KAO GDP 2.99401
4 1WQ1 AF3 4.21687
5 5HR5 ADP 6.52174
6 3R9V DXC 8.26087
7 1KPG 16A 12.6087
8 5OCA 9QZ 15.0794
9 4P7U 1PS 17.8571
Pocket No.: 3; Query (leader) PDB : 1OE0; Ligand: TTP; Similar sites found with APoc: 18
This union binding pocket(no: 3) in the query (biounit: 1oe0.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4OW0 S88 2.17391
2 2DC1 CIT 2.6087
3 3IUY AMP 2.63158
4 1DAK DPU 2.67857
5 1DAK ADP 2.67857
6 2VTD LKM 3.47826
7 1ION ADP 3.91304
8 1NHX PEP 3.91304
9 1NHX FTB 3.91304
10 3NJQ NJQ 4.14508
11 4K81 GTP 4.34783
12 1QFT HSM 5.71429
13 6FC1 MGP 6.73575
14 1L5J TRA 8.26087
15 4A34 FUL 10.2041
16 5H68 AGS 10.4348
17 1W4R TTP 11.2821
18 2QQ0 ANP 13.587
Pocket No.: 4; Query (leader) PDB : 1OE0; Ligand: TTP; Similar sites found with APoc: 9
This union binding pocket(no: 4) in the query (biounit: 1oe0.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4D81 ADP 3.47826
2 3QVV A3P 3.47826
3 5YK1 ANP 3.91304
4 5TQZ GLC 6
5 5OSW DIU 6.08696
6 3C3D FO1 7.82609
7 2FAR DTP 7.82609
8 2QQ0 TMP 13.587
9 2QQ0 ADP 13.587
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