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Receptor
PDB id Resolution Class Description Source Keywords
1O6L 1.6 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF AN ACTIVATED AKT/PROTEIN KINASE B (PKB-PIF CHIMERA) TERNARY COMPLEX WITH AMP-PNP AND GSK3 P EPTIDE HOMO SAPIENS PROTEIN KINASE TRANSFERASE SERINE/THREONINE-PROTEIN KINASE
Ref.: CRYSTAL STRUCTURE OF AN ACTIVATED AKT/PROTEIN KINASE B TERNARY COMPLEX WITH GSK-3 PEPTIDE AND AMP-PNP NAT.STRUCT.BIOL. V. 9 940 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:1480;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
GLY ARG PRO ARG THR THR SER PHE ALA GLU C:3;
Valid;
none;
submit data
1122.23 n/a O=C([...
MN A:1481;
A:1482;
Part of Protein;
Part of Protein;
none;
none;
submit data
54.938 Mn [Mn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2JDR 2.3 Å EC: 2.7.11.1 STRUCTURE OF PKB-BETA (AKT2) COMPLEXED WITH THE INHIBITOR A- 443654 HOMO SAPIENS WNT SIGNALING PATHWAY SERINE/THREONINE-PROTEIN KINASE KINASE TRANSFERASE ATP-BINDING PHOSPHORYLATION NUCLEOTIDE-BINDING ALTERNATIVE SPLICING
Ref.: A STRUCTURAL COMPARISON OF INHIBITOR BINDING TO PKB, PKA AND PKA-PKB CHIMERA J.MOL.BIOL. V. 367 882 2007
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 117 families.
1 1O6L - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
2 2JDO ic50 = 0.23 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
3 1O6K - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
4 3E88 Ki = 2 nM G96 C24 H27 N7 O3 CCn1c2cc(n....
5 2UW9 - GVP C20 H20 Cl N3 c1cc(ccc1c....
6 2JDR ic50 = 0.5 nM L20 C24 H23 N5 O Cc1c2cc(cc....
7 3D0E ic50 = 13 nM G93 C21 H27 N7 O3 CCn1c2c(cn....
8 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
9 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
70% Homology Family (20)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 91 families.
1 1O6L - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
2 2JDO ic50 = 0.23 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
3 1O6K - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
4 3E88 Ki = 2 nM G96 C24 H27 N7 O3 CCn1c2cc(n....
5 2UW9 - GVP C20 H20 Cl N3 c1cc(ccc1c....
6 2JDR ic50 = 0.5 nM L20 C24 H23 N5 O Cc1c2cc(cc....
7 3D0E ic50 = 13 nM G93 C21 H27 N7 O3 CCn1c2c(cn....
8 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
9 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
10 6CCY ic50 = 0.003 uM EX4 C29 H33 F4 N7 O C[C@@H]1CC....
11 3QKK - SMH C28 H38 N2 O7 S CCOCCN(C[C....
12 4EKL ic50 = 5 nM 0RF C24 H32 Cl N5 O2 C[C@@H]1C[....
13 3CQW ic50 = 42 nM CQW C12 H11 Cl N6 c1c(c2c([n....
14 4GV1 ic50 = 3 nM 0XZ C21 H25 Cl N6 O2 c1cc(ccc1[....
15 3MVH ic50 = 0.5 nM WFE C20 H22 F2 N6 O CCc1c[nH]c....
16 3MV5 ic50 = 180 nM XFE C11 H15 N5 Cc1c[nH]c2....
17 3QKL - SMR C29 H40 N4 O5 S CCOCC[N@@]....
18 6BUU - GLY ARG PRO ARG THR THR ZXW PHE ALA GLU n/a n/a
19 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
20 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1REK Ki = 200 nM B8L C32 H36 N2 O7 CC[C@H](C)....
2 2Z7S - P01 C19 H25 Cl N6 O CC(C)[C@H]....
3 2BIY - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
4 1UU9 ic50 = 3.8 uM BI3 C23 H20 N4 O2 c1ccc2c(c1....
5 1O6L - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Ligand no: 2; Ligand: GLY ARG PRO ARG THR THR SER PHE ALA GLU; Similar ligands found: 216
No: Ligand ECFP6 Tc MDL keys Tc
1 GLY ARG PRO ARG THR THR SER PHE ALA GLU 1 1
2 LEU PRO SER PHE GLU THR ALA LEU 0.612245 0.867647
3 LEU PRO PHE GLU ARG ALA THR VAL MET 0.611111 0.888889
4 LEU PRO PHE GLU ARG ALA THR ILE MET 0.593939 0.876712
5 ASP VAL GLN THR GLY ARG ARG PRO TYR GLU 0.567073 0.928571
6 VAL MET ALA PRO ARG THR LEU PHE LEU 0.561728 0.863014
7 GLY ARG PRO ARG THR THR ZXW PHE ALA GLU 0.560976 0.741573
8 ALA PHE ARG ILE PRO LEU THR ARG 0.56051 0.927536
9 PHE TYR ALA PRO GLU PRO ILE THR SER LEU 0.552147 0.8
10 ARG THR PHE SER PRO THR TYR GLY LEU 0.552147 0.890411
11 1IP CYS PHE SER LYS PRO ARG 0.54375 0.927536
12 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.5375 0.927536
13 GLY GLU ARG THR ILE PRO ILE THR ARG GLU 0.535948 0.926471
14 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.533333 0.942029
15 GLY PHE ARG PRO 0.533333 0.848485
16 LEU PRO PHE ASP ARG THR THR ILE MET 0.532934 0.890411
17 DPN PRO DAR DTH NH2 0.531915 0.909091
18 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.531073 0.792208
19 ARG PRO MET THR PHE LYS GLY ALA LEU 0.528736 0.876712
20 VAL PRO LEU ARG PRO MET THR TYR 0.518293 0.853333
21 ILE GLY PRO GLY ARG ALA PHE TYR THR ILE 0.511494 0.863014
22 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.511494 0.914286
23 ASP ILE ALA TYR TYR THR SER GLU PRO 0.509804 0.808219
24 SER LEU SER ARG THR PRO ALA ASP GLY ARG 0.509317 0.969697
25 GLY TYR GLU ASN PRO THR TYR LYS PHE PHE 0.508876 0.805556
26 ARG GLN PHE GLY PRO ASP PHE PRO THR ILE 0.502857 0.915493
27 LEU PRO PHE GLU LYS SER THR VAL MET 0.5 0.833333
28 SER SER ILE GLU PHE ALA ARG LEU 0.5 0.753623
29 GLY ARG PHE ALA ALA ALA ILE ALA LYS 0.5 0.720588
30 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.497355 0.853333
31 ILE GLY PRO GLY ARG ALA PHE TYR THR 0.497076 0.835616
32 MET CYS PRO ARG MET THR ALA VAL MET 0.496933 0.861111
33 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.494186 0.780822
34 THR PRO ARG VAL THR GLY GLY GLY ALA MET 0.493827 0.863014
35 ALA GLN PHE SER ALA SER ALA SER ARG 0.493056 0.787879
36 ARG PRO GLY ASN PHE LEU GLN SER ARG PRO 0.491429 0.901408
37 ARG SEP PRO VAL PHE SER 0.490798 0.835616
38 SER ALA PRO ASP THR ARG PRO ALA 0.490323 0.941176
39 SER GLU ILE GLU PHE ALA ARG LEU 0.490323 0.73913
40 PHE ASN ARG PRO VAL 0.490066 0.882353
41 DPN PRO DAR ILE NH2 0.489655 0.808824
42 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.488095 0.902778
43 GLU GLU PHE GLY ARG ALA PHE SER PHE 0.487179 0.75
44 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.486339 0.866667
45 ARG PHE PRO LEU THR PHE GLY TRP 0.486034 0.876712
46 ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 0.485714 0.927536
47 SER SER TYR ARG ARG PRO VAL GLY ILE 0.48503 0.902778
48 LYS THR PHE PRO PRO THR GLU PRO LYS 0.484663 0.880597
49 ILE SER PRO ARG THR LEU ASP ALA TRP 0.483696 0.90411
50 ILE GLY PRO GLY ARG ALA PHE TYR VAL 0.479769 0.810811
51 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.47929 0.767123
52 ILE ARG ALA ALA PRO PRO PRO LEU PHE 0.478788 0.830986
53 DPN PRO ARG 0.478261 0.818182
54 GLY LEU LEU GLY SER PRO VAL ARG ALA 0.477707 0.882353
55 ARG TYR PRO LEU THR PHE GLY TRP 0.475676 0.853333
56 ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 0.475138 0.890411
57 ARG PRO MET THR TYR LYS GLY ALA LEU 0.475138 0.842105
58 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.475 0.876712
59 ARG GLY PRO GLY CYS ALA PHE VAL THR ILE 0.474576 0.914286
60 ILE GLY PRO GLY ARG ALA PHE TYR ALA 0.473684 0.821918
61 ILE THR ASP GLN VAL PRO PHE SER VAL 0.473054 0.855072
62 CYS THR PRO SER ARG 0.472603 0.910448
63 LEU SER SER PRO VAL THR LYS SER PHE 0.472393 0.852941
64 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.471591 0.853333
65 ARG VAL ALA SER PRO THR SER GLY VAL 0.471338 0.940298
66 GLY PHE GLU PRO 0.470588 0.757576
67 GLY ASN PHE LEU GLN SER ARG 0.470588 0.768116
68 DPN PRO DAR CYS NH2 0.468966 0.80597
69 ARG ARG ARG GLU ARG SER PRO THR ARG 0.468354 0.954545
70 LYS PRO VAL LEU ARG THR ALA 0.468354 0.897059
71 GLY GLN VAL PRO PHE SER LYS GLU GLU CYS 0.467066 0.855072
72 ALA PRO ASP THR ARG PRO 0.466667 0.926471
73 ALA MET ALA PRO ARG THR LEU LEU LEU 0.465409 0.835616
74 ALA PRO ASP THR ARG PRO ALA PRO 0.464052 0.926471
75 ASN TYR THR PRO GLY PRO GLY THR ARG PHE 0.463687 0.902778
76 GLY MET PRO ARG GLY ALA 0.463576 0.791667
77 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.463277 0.90411
78 TYR PRO LYS ARG ILE ALA 0.462963 0.84507
79 ALA ARG THR GLU LEU TYR ARG SER LEU 0.462025 0.760563
80 LEU LEU PHE GLY LYS PRO VAL TYR VAL 0.461538 0.72
81 ARG PRO GLY ASN PHE LEU GLN SER ARG LEU 0.461111 0.927536
82 ARG PRO PRO ILE PHE ILE ARG ARG LEU 0.461078 0.842857
83 HIS HIS ALA SER PRO ARG LYS 0.458333 0.842857
84 PHE GLU ALA ILE PRO ALA GLU TYR LEU 0.458333 0.716216
85 ARG MET PHE PRO ASN ALA PRO TYR LEU 0.458101 0.810127
86 LEU PRO PHE ASP LYS SER THR ILE MET 0.457627 0.821918
87 GLY ARG PHE GLN VAL THR 0.456376 0.731343
88 ALA ARG MLZ SER ALA PRO ALA THR 0.45625 0.887324
89 LEU GLU LYS ALA ARG GLY SER THR TYR 0.45614 0.788732
90 ARG PHE PRO LEU THR PHE GLY TRP CYS PHE 0.453125 0.878378
91 ARG PRO PRO GLY PHE SER PRO PHE ALA 0.452941 0.898551
92 GLN ASN GLY PTR GLU ASN PRO THR TYR 0.451807 0.763158
93 GLY VAL VAL ALA SER GLN PRO ALA ARG VAL 0.45098 0.820895
94 SER ARG ASP HIS SER ARG THR PRO MET 0.449438 0.878378
95 ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO 0.449102 0.833333
96 ILE PRO LEU THR GLU GLU ALA GLU LEU 0.448052 0.797101
97 PHE LEU PRO SER ASP PHE PHE PRO SER VAL 0.447205 0.830986
98 GLU THR VAL ARG PHE GLN SER ASP 0.447205 0.776119
99 LEU LEU PHE GLY PHE PRO VAL TYR VAL 0.446429 0.739726
100 LEU LEU PHE GLY TYR PRO VAL TYR VAL 0.446429 0.739726
101 ARG GLN ALA SEP ILE GLU LEU PRO SER MET 0.446237 0.797468
102 ALA ASN SER ARG ALA PRO THR SER ILE ILE 0.445783 0.9
103 LEU PHE GLY TYR PRO VAL TYR VAL 0.445122 0.739726
104 PRO SER ILE ASP ARG SER THR LYS PRO 0.444444 0.927536
105 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.443787 0.813333
106 PHE PRO THR LYS ASP VAL ALA LEU 0.443787 0.867647
107 ASN ARG PRO ILE LEU SER LEU 0.443038 0.885714
108 LEU PRO PHE ASP LYS THR THR ILE MET 0.442529 0.808219
109 ALA ASN SER ARG ALY PRO THR SER ILE ILE 0.442529 0.901408
110 ASN GLY TYR GLU ASN PRO THR TYR LYS 0.442529 0.805556
111 ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR 0.442424 0.802817
112 SER PRO ILE VAL PRO SER PHE ASP MET 0.441176 0.797297
113 ARG VAL LEU PHE GLU ALA MET 0.440994 0.666667
114 ALA ASN SER ARG VAL PRO THR SER ILE ILE 0.440994 0.898551
115 ARG VAL ALA SEP PRO THR SER GLY VAL 0.440476 0.863014
116 ALA ASN SER ARG LEU PRO THR SER ILE ILE 0.440252 0.898551
117 ASN TYR THR PRO GLY PRO GLY ILE ARG PHE 0.440217 0.878378
118 ARG TYR PRO LEU THR LEU GLY TRP CYS PHE 0.439394 0.855263
119 SER HIS PRO ARG PRO ILE ARG VAL 0.43787 0.875
120 PHE ALA GLY LEU ARG GLN ALA VAL THR GLN 0.437086 0.720588
121 LYS GLN GLU PRO GLN GLU ILE ASP PHE 0.436047 0.794118
122 PRO ALA PRO PHE ALA SER ALA 0.435897 0.823529
123 THR PRO THR ARG ASP VAL ALA THR SER PRO 0.435583 0.941176
124 GLY GLY CYS PHE SER LYS PRO LYS MYR 0.435028 0.816901
125 ASP ILE ASN TYR TYR ALA SER GLU PRO 0.434524 0.797297
126 SER SER LEU GLU ASN PHE ARG ALA TYR VAL 0.434286 0.716216
127 ASP ILE ASN TYS TYS THR SER GLU PRO 0.433735 0.681818
128 LYS LEU PRO ALA GLN PHE TYR ILE LEU 0.432584 0.743243
129 GLY THR SER SER PRO SER ALA ASP 0.432432 0.848485
130 ALA THR VAL ARG THR TYR SER CYS 0.432258 0.732394
131 PHE ASN PHE PRO GLN ILE THR 0.432099 0.802817
132 SER PRO LYS ARG ILE ALA 0.431373 0.895522
133 ALA LEU PRO HIS ALA ILE LEU ARG LEU 0.431034 0.791667
134 GLU ALA ASP PRO THR GLY HIS SER TYR 0.430939 0.847222
135 ARG PRO ARG PRO ASP ASP LEU GLU ILE 0.430303 0.842857
136 ARG VAL SER PRO SER THR SER TYR THR PRO 0.428571 0.814286
137 ARG PRO GLN VAL PRO LEU ARG PRO MET 0.428571 0.794521
138 ASP ILE ASN TYR TYR THR SER GLU PRO 0.428571 0.797297
139 ASP ALA GLU PHE ARG HIS ASP 0.427632 0.712121
140 ACE GLN GLU ARG GLU VAL PRO CYS 0.426752 0.826087
141 ALA ASN SER ARG HIS PRO THR SER ILE ILE 0.426035 0.901408
142 GLY ALA ALA ARG ALA GLU VAL TYR LEU ARG 0.426035 0.694444
143 PHE GLN PRO GLN ASN GLY GLN PHE ILE 0.426035 0.774648
144 GLY LEU LEU GLY SEP PRO VAL ARG ALA 0.426035 0.810811
145 GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS 0.425641 0.837838
146 ARG GLN PRO ALA LYS ALA PRO LEU LEU 0.42515 0.828571
147 PRO GLU PRO THR ALA PRO PRO GLU GLU 0.425 0.838235
148 PHE LEU TRP GLY PRO ARG ALA LEU VAL 0.424731 0.808219
149 ALA ASN SER ARG TRP PRO THR SER 2KK ILE 0.424242 0.846154
150 PRO SER TYR SEP PRO THR SEP PRO SER 0.424242 0.786667
151 ARG PRO LYS ARG ILE ALA 0.424051 0.838235
152 SAC ARG GLY THR GLN THR GLU 0.423841 0.761194
153 GLY TYR GLN ASP TYR GLU PRO GLU ALA 0.423077 0.768116
154 ARG TYR PRO LEU THR PHE GLY TRP CYS PHE 0.422886 0.842105
155 GLU SER ASP PRO ILE VAL ALA GLN TYR 0.422857 0.819444
156 GLY SER ASP PRO PHE LYS 0.422078 0.863636
157 ALA ASN SER ARG TRP PRO THR SER ALY ILE 0.421875 0.88
158 ASN PRO ARG ALA MET GLN ALA LEU LEU 0.421687 0.808219
159 TYR LEU GLU PRO ALA PRO VAL THR ALA 0.421687 0.805556
160 VAL PRO LEU THR GLU ASP ALA GLU LEU 0.421384 0.808824
161 PRO GLU ALA THR ALA PRO PRO GLU GLU 0.421384 0.838235
162 GLN ALA SER TPO PRO ARG NIT 0.421348 0.802469
163 ALA ASN SER ARG TRP PRO THR SER FAK ILE 0.420513 0.857143
164 VAL MET ALA PRO ARG ALA LEU LEU LEU 0.419753 0.767123
165 THR PRO ARG ARG SER MLZ SER ALA 0.419355 0.873239
166 GLU PRO GLY GLY SER ARG 0.418301 0.909091
167 ALA ASN SER ARG TRP PRO THR SER 2KP ILE 0.41791 0.846154
168 ALA ARG SER HIS SEP TYR PRO ALA 0.417582 0.820513
169 GLY ASN TYR SER PHE TYR ALA LEU 0.417219 0.608108
170 ALA THR ALY ALA ALA ARG ALY SER ALA PRO 0.417178 0.911765
171 PHE PRO ARG PRO TRP LEU HIS GLY LEU 0.416667 0.810811
172 LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.416667 0.915493
173 ACE ALA ARG THR GLU VAL TYR NH2 0.416667 0.728571
174 ALA ALA ARG KCR SER ALA PRO ALA 0.416667 0.897059
175 ALA THR ARG ASN PHE SER GLY 0.416667 0.791045
176 SER THR SEP PRO THR PHE ASN LYS 0.41573 0.821918
177 THR PRO PRO SER PRO PHE 0.414966 0.850746
178 VAL VAL ARG PRO GLY SER LEU ASP LEU PRO 0.414773 0.913043
179 GLU GLU PRO THR VAL ILE LYS LYS TYR 0.414773 0.805556
180 GLY ASP GLU VAL LYS VAL PHE ARG 0.414634 0.746269
181 GLN PRO PRO VAL PRO PRO GLN ARG PRO MET 0.414201 0.794521
182 GLY ILE LEU GLU PHE VAL PHE THR LEU 0.414013 0.619718
183 ILE PRO ALA TYR GLY VAL LEU THR ILE 0.412791 0.791667
184 TYR LEU GLU PRO GLY PRO VAL THR ALA 0.412791 0.830986
185 TYR LEU GLU PRO GLY PRO VAL THR VAL 0.412791 0.830986
186 GLU PHE SER PRO 0.412587 0.818182
187 ARG PRO GLY ASN PHE LEU GLN ASN ARG PRO 0.4125 0.681159
188 PHE SER ALA PTR PRO SER GLU GLU ASP 0.412121 0.74026
189 LYS PRO PHE PTR VAL ASN VAL GLU PHE 0.412088 0.734177
190 ACE GLU ALA GLN THR ARG LEU 0.410596 0.695652
191 ASP PHE GLU GLU ILE PRO GLU GLU TYS 0.410405 0.643678
192 5JP PRO LYS ARG ILE ALA 0.409396 0.855072
193 PHE LEU ARG GLY ARG ALA TYR VAL LEU 0.409357 0.684932
194 GLN ASN GLY PTR VAL ASN PRO THR TYR 0.409357 0.746835
195 TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA 0.406593 0.780822
196 GLU ARG THR ILE PRO ILE THR ARG GLU 0.40625 0.897059
197 N7P THR SEP PRO SER TYR SET 0.406061 0.766234
198 GLN LEU SER PRO PHE PRO PHE ASP LEU 0.405882 0.816901
199 ACE LEU TYR ALA SER SER ASN PRO ALA PTR 0.405714 0.740741
200 PRO THR GLU PUK ARG GLU 0.405714 0.838235
201 ARG GLY PHE ALA LEU M3L SER THR HIS GLY 0.405405 0.794872
202 ILE MET ASP GLN VAL PRO PHE SER VAL 0.404494 0.794521
203 PRO PRO ARG PRO ILE TYR ASN ARG ASN 0.403409 0.875
204 LYS LEU TYR GLN ASN PRO THR THR TYR ILE 0.403315 0.773333
205 VAL ORN LEU DPN PRO VAL ORN LEU DPN PRO 0.402439 0.71831
206 PRO ARG ARG PRO VAL ILE MET ARG ARG 0.402367 0.743243
207 PRO LEU GLU PSA ARG LEU 0.402367 0.852941
208 ARG ARG ALA SEP ALA PRO LEU PRO 0.402367 0.776316
209 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.402235 0.819444
210 TYR LEU GLY GLY PRO ASP PHE PRO THR ILE 0.402174 0.797297
211 ALA THR PRO PHE GLN GLU 0.401408 0.80303
212 GLU LYS PRO SER SER SER 0.401361 0.833333
213 ALA PRO SER PTR VAL ASN VAL GLN ASN 0.401163 0.769231
214 ASP PHE GLU GLU ILE PRO GLY GLU TYR LEU 0.401099 0.756757
215 MET SER LEU PRO GLY ARG TRP LYS PRO LYS 0.4 0.855263
216 ALA ASN SER ARG TRP PRO ALY SER ILE ILE 0.4 0.866667
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2JDR; Ligand: GLY ARG PRO ARG THR THR SER PHE ALA GLU; Similar sites found with APoc: 485
This union binding pocket(no: 1) in the query (biounit: 2jdr.bio1) has 53 residues
No: Leader PDB Ligand Sequence Similarity
1 3CBC DBS None
2 4NPT 017 None
3 4YEE 4CQ None
4 2CDP GAL AAL GAL AAL GAL AAL None
5 1Q19 SSC 1.16959
6 1HXD BTN 1.24611
7 2FCU AKG 1.27796
8 2IO8 ADP 1.46199
9 3V4S ATP 1.46199
10 3K5I ADP 1.46199
11 3ZGJ RMN 1.46199
12 5HWV MBN 1.53846
13 1Q8Q MAN MMA 1.5873
14 4GYI ADP 1.75439
15 5MW8 ATP 1.75439
16 5MRH Q9Z 1.75439
17 2VPQ ANP 1.75439
18 3TII ANP 1.75439
19 5IM3 DTP 1.75439
20 4D86 ADP 1.75439
21 1F9V ADP 1.75439
22 5COU ATP 1.76471
23 4LXH C1E 1.80505
24 4TWL ASC 2.03252
25 2VQD AP2 2.04678
26 4ISS TAR 2.04678
27 6F5W KG1 2.04678
28 2HGS ADP 2.04678
29 5OLK DTP 2.04678
30 2QHS OCA 2.1097
31 3VPC ADP 2.12766
32 2HJR APR 2.13415
33 1ONI BEZ 2.17391
34 2BS5 BGC GAL FUC 2.22222
35 2DVZ GLU 2.2293
36 4R78 AMP 2.26537
37 1IOW ADP 2.28758
38 1IOW PHY 2.28758
39 1ZTH ADP 2.32558
40 1ZP9 ATP 2.32558
41 3UDZ ADP 2.33918
42 5VLQ ANP 2.33918
43 6FL8 ADP 2.33918
44 6FL8 TIY 2.33918
45 3B6R ADP 2.33918
46 2QS8 MET 2.33918
47 2Q7D ANP 2.33918
48 1NLM UD1 2.33918
49 4BG4 ADP 2.33918
50 2ZL7 FUC GAL NGA 2.37288
51 2QHV OC9 2.38095
52 4MOB ADP 2.40964
53 5A96 GTP 2.40964
54 3ZJX BOG 2.42215
55 1SDW IYT 2.54777
56 3KYF 5GP 5GP 2.5974
57 5C1P ADP 2.61438
58 5C1P DAL DAL 2.61438
59 5GZ9 ANP 2.62295
60 5I35 ANP 2.63158
61 5KJW 53C 2.63158
62 3DNT ATP 2.63158
63 5YJS SAL 2.63158
64 2R5V HHH 2.63158
65 1F52 ADP 2.63158
66 1VRP ADP 2.63158
67 4CU1 71S 2.63158
68 3TM0 ANP 2.6616
69 3TM0 B31 2.6616
70 1ULE GLA GAL NAG 2.66667
71 3NZ1 3NY 2.68199
72 1TQP ATP 2.83688
73 4HIA FMN 2.84091
74 2PYW ADP 2.92398
75 5UQD AKG 2.92398
76 3ORQ ADP 2.92398
77 3KAL ADP 2.92398
78 5ZCT ANP 2.94118
79 6CGD AKN 2.95082
80 6CGD GNP 2.95082
81 4ZNO SUC 2.98507
82 2V2G BEZ 3.00429
83 2WKQ FMN 3.01205
84 1DNA CB3 3.0303
85 1ZPR CB3 3.0303
86 1P0Z FLC 3.05344
87 5F6U 5VK 3.18471
88 1PK8 ATP 3.21637
89 1GQG DCD 3.21637
90 3HIY UTP 3.21637
91 3TY5 ADP 3.21637
92 5AE9 OKO 3.21637
93 6EZ6 C5Z 3.21637
94 1I7L ATP 3.23625
95 3TDV GDP 3.26797
96 1OBD ATP 3.26797
97 1TZD ADP 3.27273
98 1KYQ NAD 3.28467
99 5HZX 2GE 3.40909
100 3ZW2 NAG GAL FUC 3.44828
101 6FA4 D1W 3.46821
102 1GSA ADP 3.48101
103 3WVR AMP 3.50877
104 5T96 79J 3.50877
105 2P4S DIH 3.50877
106 5E5U MLI 3.51759
107 1AUX AGS 3.53698
108 1ZDQ MSM 3.57143
109 4R38 RBF 3.57143
110 4WJT NAG 3.59281
111 5V2L ATP 3.59281
112 5DYO FLU 3.77358
113 5H9P TD2 3.79747
114 2IF8 ADP 3.80117
115 4OCV ANP 3.80117
116 3VOT ADP 3.80117
117 4RF7 ARG 3.80117
118 4UWH JXM 3.80117
119 4OCJ NDG 3.80117
120 5BJZ MAL 3.80117
121 3I0O ADP 3.83481
122 5H9Q TD2 3.87097
123 2GTF P1R 3.88889
124 4RDL FUC GAL NDG FUC 3.8961
125 4ZS4 ATP 3.90879
126 4GK9 MAN BMA MAN MAN MAN 3.94265
127 6DZN AE3 3.9823
128 1QD1 FON 4
129 1WAP TRP 4
130 1S68 AMP 4.01606
131 5LJI FMN 4.05405
132 5YK1 ANP 4.09357
133 2X3J ATP 4.09357
134 4JUI EGR 4.09357
135 5FXD H7Y 4.09357
136 5JM8 ATP 4.09357
137 1U6R ADP 4.09357
138 5IQZ MAL 4.09357
139 4ZGP ADP 4.09556
140 4IAW LIZ 4.25532
141 3FXU TSU 4.2623
142 4FE2 AIR 4.31373
143 4FE2 ADP 4.31373
144 4DFU QUE 4.34783
145 5ODY 9SK 4.34783
146 3PDT ADP 4.36364
147 3QSB 743 4.38596
148 5TT6 ATP 4.38596
149 4U98 ACP 4.40529
150 2VQ5 HBA 4.47761
151 3BP1 GUN 4.48276
152 2AQX ATP 4.49827
153 1W2D ADP 4.5283
154 1W2D 4IP 4.5283
155 3ZZQ TRP 4.61538
156 5C9J STE 4.62633
157 2GQR ADP 4.64135
158 5C4L 4XR 4.6729
159 5C4L SIS 4.6729
160 5DZT AMP 4.67836
161 1EHI ADP 4.67836
162 3JU6 ANP 4.67836
163 5W75 SUC 4.67836
164 3HQP OXL 4.67836
165 3QXV MTX 4.7619
166 4RFR RHN 4.92611
167 4DDY DN6 4.94297
168 2CYB TYR 4.95356
169 3X01 AMP 4.97076
170 4PZ6 GMP 4.97076
171 1LSH PLD 4.97076
172 2ET1 GLV 4.97512
173 5LKC FUC GLA A2G 5.19481
174 4QM9 CYS 5.20231
175 2HFN FMN 5.22876
176 4LIK CIT 5.26316
177 4WOE ADP 5.26316
178 1J3R 6PG 5.26316
179 1W96 S1A 5.26316
180 4XR8 MAL 5.29801
181 4D06 NAR 5.30035
182 3RGA LSB 5.30035
183 4CC6 L5Y 5.34591
184 3CF6 SP1 5.38922
185 3RK1 ATP 5.48523
186 5VZ0 ADP 5.55556
187 1E4E ADP 5.55556
188 5TDF ADP 5.55556
189 3ETH ATP 5.55556
190 5FI4 5XV 5.55556
191 1CY2 TMP 5.55556
192 4RYV ZEA 5.80645
193 4B0T ADP 5.84795
194 2GC0 PAN 5.85106
195 3T4L ZEA 5.92593
196 3EFS BTN 6.00858
197 4O4F ATP 6.04839
198 4O4F IHP 6.04839
199 4IRX INS 6.08108
200 3KYG 5GP 5GP 6.1674
201 4OUJ LBT 6.18893
202 3W0O HY0 6.30372
203 3W0O ADP 6.30372
204 5ACM MBT 6.30631
205 4BJ8 BTN 6.34921
206 1IA9 ANP 6.42857
207 2QK4 ATP 6.43275
208 1T36 ADP 6.43275
209 5KWY C3S 6.47773
210 2GJ3 FAD 6.66667
211 1NBU PH2 6.72269
212 5OES ADP 6.72515
213 5G48 1FL 6.72515
214 4NS0 PIO 6.76692
215 4LH7 1X8 6.81115
216 3SAO DBH 6.875
217 4WW7 AMP 6.89655
218 5DKK FMN 6.89655
219 2QL9 CIT 6.93642
220 4O1P ANP 7.01754
221 2YRX AMP 7.01754
222 1M0W ANP 7.01754
223 5VAD PRO 7.01754
224 5H9Y BGC BGC BGC BGC 7.01754
225 6D6L FY4 7.05882
226 5HWK BEZ 7.08333
227 3PN1 IVH 7.2327
228 4P25 FUC GAL NAG FUC 7.28477
229 4PU5 ANP 7.30994
230 2YW2 ATP 7.30994
231 2GUC MAN 7.37705
232 2GUD MAN 7.37705
233 2NUO BGC 7.37705
234 2HYQ MAN MAN 7.37705
235 2HYR BGC GLC 7.37705
236 2NU5 NAG 7.37705
237 6EBQ FMN 7.5
238 1A8U BEZ 7.58123
239 4IX4 ADP 7.60234
240 4AZW ATP 7.60234
241 2JK0 ASP 7.69231
242 4XYM A12 7.82609
243 4Q5H ANP 7.89474
244 1TLL FAD 7.89474
245 2FB3 5AD 7.94118
246 2AGC DAO 8.02469
247 4MV1 ADP 8.11966
248 4XZ3 ACP 8.26087
249 3RDV ASP SER TRP LYS ASP GLY CYS TYR 8.33333
250 5DQ8 FLF 8.33333
251 4Y24 TD2 8.44156
252 5HV7 RBL 8.47953
253 2YKL NLD 8.49057
254 1YRO UDP 8.74126
255 6C1S EFV 8.77193
256 5TZO 7V7 9.04255
257 5EJL C2E 9.06433
258 1Z2P I3S 9.25926
259 1Z2P ACP 9.25926
260 2GQS C2R 9.2827
261 2GQS ADP 9.2827
262 5KBF CMP 9.30233
263 2XG5 EC5 9.63303
264 2XG5 EC2 9.63303
265 3W6G FLC 9.72222
266 2PR5 FMN 9.84848
267 5IGI GMP 9.96678
268 5IGI ZIT 9.96678
269 1LFO OLA 10.1562
270 1F5F DHT 10.2439
271 4OFG PCG 10.4167
272 2BKK ADP 10.6509
273 4Z4P SAH 10.8434
274 2PUL ACP 11.1111
275 2P7Q GG6 11.2782
276 2FT0 ACO 11.4894
277 4NG2 OHN 11.5044
278 5CKW ANP 11.6959
279 4LO2 GAL BGC 11.8243
280 1KDK DHT 11.8644
281 1UPR 4IP 12.1951
282 5NLD LBT 12.2302
283 6GBV FMN 12.3288
284 5Y4R C2E 12.4138
285 4RT1 C2E 13.3929
286 1FWV SGA MAG FUC 13.4328
287 5K2M ADP 13.5531
288 4OAV ACP 13.7427
289 4GLW 0XT 13.7705
290 5LXT ACP 13.986
291 2QLU ADE 14.0127
292 3WG3 A2G GAL NAG FUC 14.0449
293 3HAV ATP 15.7191
294 3ZXE PGZ 15.7895
295 3VPD ANP 16.3701
296 5DJT FMN 16.5517
297 5EFW FMN 16.5517
298 4IZY 1J2 16.6667
299 4CYI ATP 16.6667
300 2CSN CKI 17.1717
301 4UX9 ANP 17.2515
302 4XMF HSM 17.9348
303 4XH0 ADP 18.7134
304 5BVE 4VG 19.0058
305 4H3Q ANP 19.0058
306 4H3P ANP 19.0058
307 5MY8 RXZ 19.2982
308 5H5O PCG 19.3798
309 3VHE 42Q 19.883
310 1BHX ASP PHE GLU GLU ILE 20
311 3VPB ADP 21.4286
312 2RDE C2E 22.3108
313 5C03 AGS 22.807
314 6GNO XDI 22.963
315 4WOV 3SM 24.6057
316 5KO1 6UY 25.4417
317 3T2W BTN 26.2295
318 4FL3 ANP 26.3158
319 5HCY 60D 26.8882
320 4BTK DTQ 27.003
321 5LPZ ADP 27.4096
322 3H9R TAK 27.5758
323 3UIM ANP 28.2209
324 3C1X CKK 28.3626
325 4CRL C1I 28.3626
326 5ZTN CUR 28.655
327 3PP0 03Q 28.6982
328 5QIN J2V 28.7975
329 1OPK P16 28.9474
330 6FYL 3NG 28.9474
331 2WU6 DKI 28.9474
332 6ES0 BW8 29.0221
333 4CLI 5P8 29.052
334 6FYV 3NG 29.0801
335 4E93 GUI 29.2398
336 3E7O 35F 29.2398
337 3LXK MI1 29.3578
338 5Y86 HRM 29.5322
339 4KBA 1QM 29.8246
340 5X8I SQZ 29.8246
341 3E8N VRA 29.912
342 3E8N ATP 29.912
343 6G33 5ID 30.0885
344 5EOB 5QQ 30.094
345 4QTB 38Z 30.117
346 4Y85 499 30.1205
347 3KRL KRL 30.1493
348 6A1G 9OL 30.7018
349 5LPB ADP 30.7432
350 3PLS ANP 30.8725
351 6GIN IR2 30.897
352 4E1Z 0MX 30.9278
353 3KMW ATP 30.9963
354 3VRY B43 31.2866
355 4P5Z Q7M 31.2866
356 5NKB 8ZT 31.3725
357 2OFV 242 31.4079
358 3LXN MI1 31.4465
359 3GQI ACP 31.5951
360 4AUA 4AU 31.5961
361 2PVF ACP 31.7365
362 6GWR FEW 31.746
363 5WO4 B7V 31.7881
364 2OO8 RAJ 32.1767
365 4K33 ACP 32.3077
366 5T8O 76Z 32.3782
367 5OKT 9XK 32.4841
368 1VJY 460 32.6733
369 4LOO SB4 32.7485
370 1OUK 084 32.7485
371 4UXL 5P8 32.9193
372 5EFQ ADP 33.0409
373 2H8H H8H 33.0409
374 1Y57 MPZ 33.0409
375 4GJ3 0XP 33.1126
376 3SRV S19 33.213
377 3NW7 LGV 33.2248
378 3HMO STU 33.3333
379 6C7Y ADP 33.5664
380 4U0I 0LI 33.6508
381 6GQM F8H 33.8415
382 3RI1 3RH 33.8658
383 4Y93 746 33.9181
384 3SXS PP2 33.9552
385 4F4P 0SB 34.0659
386 5UR1 YY9 34.0836
387 2XVD AS6 34.106
388 1K3A ACP 34.1137
389 3EKK GS2 34.202
390 4ASE AV9 34.2105
391 3BU5 ATP 34.3137
392 1IR3 ANP 34.3137
393 2Y6O 1N1 34.3643
394 5JFS 6K0 35.0649
395 5WNL STU 35.0877
396 1BYG STU 35.6115
397 4YZC STU 35.6725
398 5JKG 6LF 35.6913
399 1JPA ANP 35.8974
400 4EWH T77 36
401 5N87 N66 36.1022
402 4YMJ 4EJ 36.1842
403 4IDT T28 36.2573
404 5USZ SKE 36.3322
405 4BHN BH9 36.5269
406 5TA6 79D 36.5497
407 5HES 032 36.8078
408 5U6C 7YS 36.8254
409 3GNI ATP 36.8421
410 4TWP AXI 36.9004
411 1U59 STU 36.9338
412 2A19 ANP 36.9718
413 4AG8 AXI 37.0253
414 5MJA 7O3 37.0492
415 2G30 ALA ALA PHE 37.5
416 3FC2 IBI 37.6119
417 5CEO 50D 38
418 4NM5 ADP 38.0117
419 2JLD AG1 38.0117
420 4FF8 14S 38.0805
421 3ALN ANP 38.2263
422 3ZRM ZRM 38.3041
423 3F7Z 34O 38.3041
424 4CSV STI 38.5455
425 1O9U ADZ 38.5965
426 4AT3 LTI 38.796
427 2X2M X2M 38.8535
428 2B9H ADP 38.8889
429 2B9F ADP 38.8889
430 4ONA UW1 38.8889
431 2B9I ADP 38.8889
432 2B9J ADP 38.8889
433 5FBN 5WF 39.1144
434 3G5D 1N1 39.1608
435 3IGO ANP 39.1813
436 3HZT J60 39.4737
437 2V7O DRN 39.5833
438 2HK5 1BM 39.6296
439 4QMN DB8 40
440 5AWM ANP 40.0585
441 1CM8 ANP 40.0585
442 5TO8 7FM 40.0709
443 3BZ3 YAM 40.5797
444 4WHZ 3NL 40.6433
445 3SLS 77D 40.7895
446 3SLS ANP 40.7895
447 3PTG 932 40.9357
448 3TTI KBI 40.9357
449 3GC0 AMP 41.3374
450 2VZ6 FEF 41.5335
451 2WEL K88 41.5902
452 5H2U 1N1 41.9476
453 6CMJ F6J 42.0561
454 4NST ADP 42.1053
455 4NST AF3 42.1053
456 5EKO N17 42.1053
457 3GC8 B45 42.1622
458 4I6H 1C8 42.2078
459 5EH0 5NW 42.2481
460 5VC5 96M 42.9066
461 6CZ3 FLJ 43.9394
462 1ZY5 ANP 44.2244
463 4RFM 3P6 44.3609
464 2ZV2 609 44.9664
465 2BPM 529 44.9838
466 4AU8 Z3R 45.2703
467 5JGA 6KC 45.3968
468 2VN9 GVD 45.5149
469 4FG8 ATP 45.7143
470 4BCQ TJF 45.8472
471 4BCM T7Z 45.8472
472 4CFU 2WC 45.8746
473 4BCN T9N 46
474 6GUE FB8 46.0265
475 3O0G 3O0 46.2329
476 1UNH IXM 46.2329
477 2F57 23D 46.3722
478 5LMK 6ZK 46.4646
479 2WEI VGG 46.6899
480 4L9I 8PR 47.6608
481 4PNI KQQ 47.6608
482 1PHK ATP 47.9866
483 6GU6 1QK 48.0132
484 5HQ0 LZ9 48.0132
485 4WNK 453 49.1228
Pocket No.: 2; Query (leader) PDB : 2JDR; Ligand: L20; Similar sites found with APoc: 485
This union binding pocket(no: 2) in the query (biounit: 2jdr.bio1) has 53 residues
No: Leader PDB Ligand Sequence Similarity
1 3CBC DBS None
2 4NPT 017 None
3 4YEE 4CQ None
4 2CDP GAL AAL GAL AAL GAL AAL None
5 1Q19 SSC 1.16959
6 1HXD BTN 1.24611
7 2FCU AKG 1.27796
8 2IO8 ADP 1.46199
9 3V4S ATP 1.46199
10 3K5I ADP 1.46199
11 3ZGJ RMN 1.46199
12 5HWV MBN 1.53846
13 1Q8Q MAN MMA 1.5873
14 4GYI ADP 1.75439
15 5MW8 ATP 1.75439
16 5MRH Q9Z 1.75439
17 2VPQ ANP 1.75439
18 3TII ANP 1.75439
19 5IM3 DTP 1.75439
20 4D86 ADP 1.75439
21 1F9V ADP 1.75439
22 5COU ATP 1.76471
23 4LXH C1E 1.80505
24 4TWL ASC 2.03252
25 2VQD AP2 2.04678
26 4ISS TAR 2.04678
27 6F5W KG1 2.04678
28 2HGS ADP 2.04678
29 5OLK DTP 2.04678
30 2QHS OCA 2.1097
31 3VPC ADP 2.12766
32 2HJR APR 2.13415
33 1ONI BEZ 2.17391
34 2BS5 BGC GAL FUC 2.22222
35 2DVZ GLU 2.2293
36 4R78 AMP 2.26537
37 1IOW ADP 2.28758
38 1IOW PHY 2.28758
39 1ZTH ADP 2.32558
40 1ZP9 ATP 2.32558
41 3UDZ ADP 2.33918
42 5VLQ ANP 2.33918
43 6FL8 ADP 2.33918
44 6FL8 TIY 2.33918
45 3B6R ADP 2.33918
46 2QS8 MET 2.33918
47 2Q7D ANP 2.33918
48 1NLM UD1 2.33918
49 4BG4 ADP 2.33918
50 2ZL7 FUC GAL NGA 2.37288
51 2QHV OC9 2.38095
52 4MOB ADP 2.40964
53 5A96 GTP 2.40964
54 3ZJX BOG 2.42215
55 1SDW IYT 2.54777
56 3KYF 5GP 5GP 2.5974
57 5C1P ADP 2.61438
58 5C1P DAL DAL 2.61438
59 5GZ9 ANP 2.62295
60 5I35 ANP 2.63158
61 5KJW 53C 2.63158
62 3DNT ATP 2.63158
63 5YJS SAL 2.63158
64 2R5V HHH 2.63158
65 1F52 ADP 2.63158
66 1VRP ADP 2.63158
67 4CU1 71S 2.63158
68 3TM0 ANP 2.6616
69 3TM0 B31 2.6616
70 1ULE GLA GAL NAG 2.66667
71 3NZ1 3NY 2.68199
72 1TQP ATP 2.83688
73 4HIA FMN 2.84091
74 2PYW ADP 2.92398
75 5UQD AKG 2.92398
76 3ORQ ADP 2.92398
77 3KAL ADP 2.92398
78 5ZCT ANP 2.94118
79 6CGD AKN 2.95082
80 6CGD GNP 2.95082
81 4ZNO SUC 2.98507
82 2V2G BEZ 3.00429
83 2WKQ FMN 3.01205
84 1DNA CB3 3.0303
85 1ZPR CB3 3.0303
86 1P0Z FLC 3.05344
87 5F6U 5VK 3.18471
88 1PK8 ATP 3.21637
89 1GQG DCD 3.21637
90 3HIY UTP 3.21637
91 3TY5 ADP 3.21637
92 5AE9 OKO 3.21637
93 6EZ6 C5Z 3.21637
94 1I7L ATP 3.23625
95 3TDV GDP 3.26797
96 1OBD ATP 3.26797
97 1TZD ADP 3.27273
98 1KYQ NAD 3.28467
99 5HZX 2GE 3.40909
100 3ZW2 NAG GAL FUC 3.44828
101 6FA4 D1W 3.46821
102 1GSA ADP 3.48101
103 3WVR AMP 3.50877
104 5T96 79J 3.50877
105 2P4S DIH 3.50877
106 5E5U MLI 3.51759
107 1AUX AGS 3.53698
108 1ZDQ MSM 3.57143
109 4R38 RBF 3.57143
110 4WJT NAG 3.59281
111 5V2L ATP 3.59281
112 5DYO FLU 3.77358
113 5H9P TD2 3.79747
114 2IF8 ADP 3.80117
115 4OCV ANP 3.80117
116 3VOT ADP 3.80117
117 4RF7 ARG 3.80117
118 4UWH JXM 3.80117
119 4OCJ NDG 3.80117
120 5BJZ MAL 3.80117
121 3I0O ADP 3.83481
122 5H9Q TD2 3.87097
123 2GTF P1R 3.88889
124 4RDL FUC GAL NDG FUC 3.8961
125 4ZS4 ATP 3.90879
126 4GK9 MAN BMA MAN MAN MAN 3.94265
127 6DZN AE3 3.9823
128 1QD1 FON 4
129 1WAP TRP 4
130 1S68 AMP 4.01606
131 5LJI FMN 4.05405
132 5YK1 ANP 4.09357
133 2X3J ATP 4.09357
134 4JUI EGR 4.09357
135 5FXD H7Y 4.09357
136 5JM8 ATP 4.09357
137 1U6R ADP 4.09357
138 5IQZ MAL 4.09357
139 4ZGP ADP 4.09556
140 4IAW LIZ 4.25532
141 3FXU TSU 4.2623
142 4FE2 AIR 4.31373
143 4FE2 ADP 4.31373
144 4DFU QUE 4.34783
145 5ODY 9SK 4.34783
146 3PDT ADP 4.36364
147 3QSB 743 4.38596
148 5TT6 ATP 4.38596
149 4U98 ACP 4.40529
150 2VQ5 HBA 4.47761
151 3BP1 GUN 4.48276
152 2AQX ATP 4.49827
153 1W2D ADP 4.5283
154 1W2D 4IP 4.5283
155 3ZZQ TRP 4.61538
156 5C9J STE 4.62633
157 2GQR ADP 4.64135
158 5C4L 4XR 4.6729
159 5C4L SIS 4.6729
160 5DZT AMP 4.67836
161 1EHI ADP 4.67836
162 3JU6 ANP 4.67836
163 5W75 SUC 4.67836
164 3HQP OXL 4.67836
165 3QXV MTX 4.7619
166 4RFR RHN 4.92611
167 4DDY DN6 4.94297
168 2CYB TYR 4.95356
169 3X01 AMP 4.97076
170 4PZ6 GMP 4.97076
171 1LSH PLD 4.97076
172 2ET1 GLV 4.97512
173 5LKC FUC GLA A2G 5.19481