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Receptor
PDB id Resolution Class Description Source Keywords
1NW7 2.1 Å EC: 2.1.1.72 STRUCTURE OF THE BETA CLASS N6-ADENINE DNA METHYLTRANSFERASE BOUND TO S-ADENOSYL-L-HOMOCYSTEINE RHODOBACTER SPHAEROIDES ADENINE DNA METHYLTRANSFERASE S-ADENOSYL HOMOCYSTEINE ROSSFOLD TRANSFERASE
Ref.: STRUCTURES OF LIGANDED AND UNLIGANDED RSRI N6-ADENI METHYLTRANSFERASE: A DISTINCT ORIENTATION FOR ACTIV COFACTOR BINDING J.BIOL.CHEM. V. 278 26094 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:501;
A:502;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
SAH A:401;
Valid;
none;
Kd = 8.1 uM
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1NW5 2.05 Å EC: 2.1.1.72 STRUCTURE OF THE BETA CLASS N6-ADENINE DNA METHYLTRANSFERASE BOUND TO S-ADENOSYLMETHIONINE RHODOBACTER SPHAEROIDES ADENINE DNA METHYLTRANSFERASE S-ADENOSYLMETHIONINE ROSSMANTRANSFERASE
Ref.: STRUCTURES OF LIGANDED AND UNLIGANDED RSRI N6-ADENI METHYLTRANSFERASE: A DISTINCT ORIENTATION FOR ACTIV COFACTOR BINDING J.BIOL.CHEM. V. 278 26094 2003
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1NW5 Kd = 6.1 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1NW7 Kd = 8.1 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1NW6 - SFG C15 H23 N7 O5 c1nc(c2c(n....
4 1EG2 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1NW5 Kd = 6.1 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1NW7 Kd = 8.1 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1NW6 - SFG C15 H23 N7 O5 c1nc(c2c(n....
4 1EG2 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1NW5 Kd = 6.1 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1NW7 Kd = 8.1 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1NW6 - SFG C15 H23 N7 O5 c1nc(c2c(n....
4 1EG2 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1NW5; Ligand: SAM; Similar sites found with APoc: 651
This union binding pocket(no: 1) in the query (biounit: 1nw5.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 2HMT NAI None
2 4YAG NAI 1.03806
3 3GEG NAD 1.21457
4 1PR9 NAP 1.22951
5 3D3W NAP 1.22951
6 3K7M FAD 1.25392
7 3G2O SAM 1.33779
8 2AOT SAH 1.36986
9 1JQD SAH 1.36986
10 1XKQ NDP 1.42857
11 5L95 AMP 1.43369
12 3UOY FAD 1.5674
13 3UOY NAP 1.5674
14 5K4W NAI 1.5674
15 5K4W THR 1.5674
16 1RJD SAM 1.5674
17 2VDV SAM 1.62602
18 4YAC NAI 1.6835
19 2HXW FLC 1.68776
20 5XLX SAH 1.77305
21 5O42 BGC 1.82482
22 5O42 9JW 1.82482
23 5O42 NAD 1.82482
24 5DM1 5D7 1.87266
25 5DM1 SAH 1.87266
26 1G55 SAH 1.88088
27 2NPX NAD 1.88088
28 2NPX FAD 1.88088
29 1QO8 FAD 1.88088
30 6F97 FAD 1.88088
31 2IVD FAD 1.88088
32 5DNK SAH 1.88088
33 3QJ4 FAD 1.88088
34 2C7G FAD 1.88088
35 3KLJ FAD 1.88088
36 2IZ1 ATR 1.88088
37 1GET FAD 1.88088
38 1GET NAP 1.88088
39 1ZK7 FAD 1.88088
40 4EUE NAI 1.88088
41 3SSO SAH 1.88088
42 4D5G FAD 1.88088
43 4D5G TPP 1.88088
44 2C7G ODP 1.88088
45 4Y9D NAI 1.96721
46 4FN4 NAD 1.9685
47 3O7W SAM 2.04082
48 5KXE 6Y2 2.05761
49 1WG8 SAM 2.10526
50 1LSS NAD 2.14286
51 1SQF SAM 2.19436
52 5WP5 SAH 2.19436
53 3M6W SAM 2.19436
54 5YF1 8V0 2.19436
55 2VVM FAD 2.19436
56 5WP4 SAH 2.19436
57 2VVL FAD 2.19436
58 1RSG FAD 2.19436
59 4REP FAD 2.19436
60 2BRY FAD 2.19436
61 5YF1 SFG 2.19436
62 3LST SAH 2.19436
63 2GV8 FAD 2.19436
64 1YY5 FAD 2.19436
65 1VQW FAD 2.19436
66 2GVC FAD 2.19436
67 1XHC FAD 2.19436
68 4ZCC NAI 2.19436
69 4ZCC FAD 2.19436
70 4TXI FAD 2.19436
71 4MOP 2H5 2.19436
72 6F7L FAD 2.19436
73 3CGD COA 2.19436
74 5MBX FAD 2.19436
75 5MBX SP5 2.19436
76 3CGD FAD 2.19436
77 3NDJ JHZ 2.19436
78 3NDJ SAH 2.19436
79 4MO2 FDA 2.19436
80 3CGB FAD 2.19436
81 3CGD NAD 2.19436
82 4MO2 FAD 2.19436
83 1KYZ SAH 2.19436
84 3A4V PYR 2.2082
85 3A4V NAD 2.2082
86 2UYQ SAM 2.25806
87 3HVJ 705 2.26244
88 2DTX BMA 2.27273
89 3DTU DXC 2.29008
90 2WSB NAD 2.3622
91 1ZQ9 SAM 2.45614
92 3ZV6 4HB 2.4911
93 3ZV6 NAD 2.4911
94 5E72 SAM 2.50784
95 2EJU SAH 2.50784
96 5MW4 5JU 2.50784
97 4M73 M72 2.50784
98 4KIB SAH 2.50784
99 3QOX SAH 2.50784
100 3C6K MTA 2.50784
101 4M73 SAH 2.50784
102 4D04 NAP 2.50784
103 4D04 FAD 2.50784
104 3L9W AMP 2.50784
105 3L9W GSH 2.50784
106 4TM3 FAD 2.50784
107 3E1T FAD 2.50784
108 3S5W FAD 2.50784
109 3NTA FAD 2.50784
110 4HA6 FAD 2.50784
111 4RPL FAD 2.50784
112 4RPL 3UC 2.50784
113 2HQM FAD 2.50784
114 1E1M FAD 2.50784
115 1E1M NAP 2.50784
116 3T31 DCQ 2.50784
117 3T31 FAD 2.50784
118 6FHO FAD 2.50784
119 3C6K SPD 2.50784
120 5K0A FAD 2.50784
121 4JDR FAD 2.50784
122 4DSG FAD 2.50784
123 4DSG UDP 2.50784
124 4YT4 FE9 2.50784
125 1I8T FAD 2.50784
126 3LAD FAD 2.50784
127 2WET FAD 2.50784
128 4FC7 NAP 2.52708
129 4FC7 COA 2.52708
130 6ECU SAH 2.53165
131 4NEC SAH 2.65152
132 3DUW SAH 2.69058
133 1XSE NDP 2.71186
134 4R6W PC 2.71318
135 4R6W SAH 2.71318
136 4P86 5GP 2.73224
137 4P83 U5P 2.74725
138 3PT9 SAH 2.82132
139 5U19 SAH 2.82132
140 5U19 827 2.82132
141 6D6Y SAH 2.82132
142 1U2Z SAH 2.82132
143 6BQ6 TER 2.82132
144 4KRI SAH 2.82132
145 2ZUX RAM 2.82132
146 4N49 SAM 2.82132
147 4AZW SAM 2.82132
148 4B63 FAD 2.82132
149 4B63 ORN 2.82132
150 4B63 NAP 2.82132
151 2YG3 FAD 2.82132
152 5J5Z FAD 2.82132
153 6H3O FAD 2.82132
154 2JHP SAH 2.82132
155 1Z45 NAD 2.82132
156 4YNU FAD 2.82132
157 3RNM FAD 2.82132
158 4YNU LGC 2.82132
159 2IXB A2G 2.82132
160 2IXB NAD 2.82132
161 1OC2 NAD 2.82132
162 5U8U FAD 2.82132
163 5N0J FAD 2.849
164 2Q0L FAD 2.89389
165 1IY8 NAD 2.99625
166 2PWY SAH 3.10078
167 5ZW3 SAH 3.11111
168 5FTW SAH 3.125
169 1GEG NAD 3.125
170 3S1S SAH 3.1348
171 1MO9 KPC 3.1348
172 1MO9 FAD 3.1348
173 5BJX UDP 3.1348
174 5BJX NAD 3.1348
175 2CDU FAD 3.1348
176 4IV9 FAD 3.1348
177 5T67 JHZ 3.1348
178 3X0V FAD 3.1348
179 5MZI FYK 3.1348
180 5MZI FAD 3.1348
181 5GSN FAD 3.1348
182 5T67 SAH 3.1348
183 2CDU ADP 3.1348
184 3P9C SAH 3.1348
185 3GD4 NAD 3.1348
186 2DKH FAD 3.1348
187 2DKH 3HB 3.1348
188 5Y77 FAD 3.1348
189 4XQC NAD 3.1348
190 4XQC 13D 3.1348
191 1COY FAD 3.1348
192 3GD4 FAD 3.1348
193 2RGJ FAD 3.1348
194 1EK6 UPG 3.1348
195 1EK6 NAI 3.1348
196 1SZ2 BGC 3.1348
197 1GZ6 NAI 3.1348
198 3FRH SAH 3.16206
199 5W7M SAH 3.20513
200 2YY7 NAD 3.20513
201 2EWM NAD 3.21285
202 1BDB NAD 3.2491
203 1IM8 SAI 3.27869
204 6F9Q NAD 3.30882
205 1JNR FAD 3.33333
206 4ITU NAI 3.34572
207 4ITU 1HS 3.34572
208 3FPF TNA 3.3557
209 3FPF MTA 3.3557
210 1FNZ A2G 3.37553
211 1XCL SAH 3.40426
212 5JJR SAH 3.44828
213 1YQZ FAD 3.44828
214 3RKR NAP 3.44828
215 1GTE FAD 3.44828
216 3FPZ AHZ 3.44828
217 5WS9 AMP 3.44828
218 2XVE FAD 3.44828
219 5XNC MTA 3.44828
220 5BUK FAD 3.44828
221 1V6A TRE 3.44828
222 4U8P FDA 3.44828
223 3I53 SAH 3.44828
224 4U8P UDP 3.44828
225 2ZWA SAH 3.44828
226 2E5V FAD 3.44828
227 5BVA FAD 3.44828
228 5JGL SAM 3.46021
229 4NBW NAD 3.50195
230 1VE3 SAM 3.52423
231 5W7K SAH 3.52564
232 1XTP SAI 3.54331
233 3VYW SAM 3.57143
234 1XG5 NAP 3.58423
235 4YRY FAD 3.62319
236 4YRY NAD 3.62319
237 4O0L NDP 3.63636
238 5VN0 FAD 3.66795
239 5VN0 NAI 3.66795
240 3A27 SAM 3.67647
241 1Z3C SA8 3.69128
242 3OFK SAH 3.7037
243 1JQ3 AAT 3.71622
244 2PXX SAH 3.72093
245 3GRU AMP 3.72881
246 6B92 SAH 3.7415
247 4ONQ SFG 3.76176
248 4X60 3XV 3.76176
249 4X60 SFG 3.76176
250 4GQB 0XU 3.76176
251 6ARJ BW4 3.76176
252 6ARJ SAH 3.76176
253 5FA5 MTA 3.76176
254 2PT9 2MH 3.76176
255 3P2E SAH 3.76176
256 5DX8 SFG 3.76176
257 5DXA SFG 3.76176
258 6IS0 SAH 3.76176
259 5DWQ SFG 3.76176
260 5DX1 SFG 3.76176
261 5DX0 SFG 3.76176
262 1UWK NAD 3.76176
263 1UWK URO 3.76176
264 1FP1 SAH 3.76176
265 1PS9 FAD 3.76176
266 2PT9 S4M 3.76176
267 1X87 NAD 3.76176
268 4FWE FAD 3.76176
269 2QA1 FAD 3.76176
270 5TTJ FAD 3.76176
271 3WMX NAD 3.76176
272 1FP2 SAH 3.76176
273 4JNA FAD 3.76176
274 1PJS NAD 3.76176
275 3IHG FAD 3.76176
276 2A14 SAH 3.80228
277 1QB7 ADE 3.81356
278 1MZV AMP 3.82979
279 4YSX FAD 3.84615
280 5OJI NAP 3.84615
281 5OJI ISN 3.84615
282 3H2B SAH 3.94089
283 2XVM SAH 4.0201
284 1P1C SAH 4.0201
285 4M37 SAH 4.07523
286 4M38 SAH 4.07523
287 5ICE 2H4 4.07523
288 5KOK S9T 4.07523
289 5ICE SAH 4.07523
290 4PIO SAH 4.07523
291 4PIO AVI 4.07523
292 5KOK R9T 4.07523
293 1F3L SAH 4.07523
294 5KOK SAH 4.07523
295 3AXB PRO 4.07523
296 3AXB FAD 4.07523
297 2Z3Y F2N 4.07523
298 3CTY FAD 4.07523
299 1REO FAD 4.07523
300 1PN0 FAD 4.07523
301 1PN0 IPH 4.07523
302 4C3Y FAD 4.07523
303 4C3Y ANB 4.07523
304 3ABI NAD 4.07523
305 1YBH FAD 4.07523
306 2FK8 SAM 4.08805
307 5BW4 SAM 4.11985
308 1UY4 XYP XYP XYP XYP 4.13793
309 3GU3 SAH 4.22535
310 2I7C AAT 4.24028
311 3LCV SAM 4.27046
312 1N2X SAM 4.31894
313 1HGX 5GP 4.37158
314 6GFK SAH 4.38247
315 6FDF SAH 4.38871
316 2JB2 FAD 4.38871
317 2JB2 PHE 4.38871
318 2EG5 SAH 4.38871
319 1LVL NAD 4.38871
320 1ZGA SAH 4.38871
321 3NYC IAR 4.38871
322 3NYC FAD 4.38871
323 1XDS SAM 4.38871
324 6GKV SAH 4.38871
325 5I39 FAD 4.38871
326 5NMX FAD 4.38871
327 3Q9T FAY 4.38871
328 1Q1R FAD 4.38871
329 4NTD FAD 4.38871
330 2GJP MAL 4.38871
331 3QVP FAD 4.38871
332 5NMX NAP 4.38871
333 1LVL FAD 4.38871
334 4J36 1HR 4.38871
335 4J36 FAD 4.38871
336 4K5S FAD 4.38871
337 4K5S PM0 4.38871
338 1R18 SAH 4.40529
339 1I1N SAH 4.42478
340 3NUG NAD 4.45344
341 2BD0 NAP 4.5082
342 1TPY SAH 4.52962
343 1KPG SAH 4.52962
344 1KPH SAH 4.52962
345 1D4D FAD 4.54545
346 5KVA SAM 4.67626
347 3EVF SAH 4.69314
348 3EVF GTA 4.69314
349 5GVR LMR 4.70085
350 3TLJ SAH 4.70219
351 3LKZ SFG 4.70219
352 5THZ SAH 4.70219
353 5THY SAH 4.70219
354 5F8F SFG 4.70219
355 3UCL CYH 4.70219
356 3UCL NAP 4.70219
357 3UCL FAD 4.70219
358 4USQ FAD 4.70219
359 3WGT FAD 4.70219
360 3WGT QSC 4.70219
361 2C31 ADP 4.70219
362 2C31 TZD 4.70219
363 5TWB FAD 4.70219
364 5ZBC FAD 4.70219
365 2Y6Q I7T 4.70219
366 2Y6Q FAD 4.70219
367 1KYQ NAD 4.74453
368 6F5Z SAH 4.7619
369 3SJ7 NDP 4.7619
370 3G89 SAM 4.81928
371 3T7S SAM 4.85075
372 1L1E SAH 4.87805
373 1YC5 NCA 4.87805
374 4BUZ OAD 4.87805
375 4BUZ OCZ 4.87805
376 4BUZ NAD 4.87805
377 3MAG SAH 4.88599
378 5DLY SAH 4.88722
379 5DLY 5D7 4.88722
380 5GWX SAR 4.92958
381 5GWX SAM 4.92958
382 3BGD SAH 5
383 1EJ0 SAM 5
384 3BGD PM6 5
385 3VSE SAH 5.01567
386 2JJQ SAH 5.01567
387 5NA1 FAD 5.01567
388 6GAS FAD 5.01567
389 1RYI GOA 5.01567
390 1RYI FAD 5.01567
391 1H82 FAD 5.01567
392 1Q9I TEO 5.01567
393 1Q9I FAD 5.01567
394 1H82 GZZ 5.01567
395 3AYI FAD 5.01567
396 3AYI HCI 5.01567
397 3MQ2 SAH 5.04587
398 3MCT SAH 5.05051
399 3LXD FAD 5.06024
400 6ECW SAH 5.07937
401 3A4T SFG 5.10949
402 2ZFU SAH 5.11628
403 3H8V ATP 5.13699
404 6AR9 3L4 5.14706
405 3FUU ADN 5.16605
406 1DQN IMU 5.21739
407 5XWV NDP 5.24194
408 5XWV 8H6 5.24194
409 3RFV 15L 5.24345
410 3RFV NAI 5.24345
411 2YX1 SFG 5.32915
412 5G3U FDA 5.32915
413 5G3U ITW 5.32915
414 3GF4 FAD 5.32915
415 3ICT FAD 5.32915
416 3GF4 UPG 5.32915
417 3ICR FAD 5.32915
418 3ICS FAD 5.32915
419 4PPF FLC 5.32915
420 5HSA FAS 5.32915
421 3ICS ADP 5.32915
422 1JXN MFU 5.3719
423 4OBW SAM 5.44747
424 5MGZ SAH 5.50847
425 2XYQ SAH 5.51724
426 3JWH SAH 5.52995
427 3LCC SAH 5.53191
428 2P41 SAH 5.57377
429 5FA8 SAM 5.59006
430 5ULP KB1 5.59701
431 2BZG SAH 5.60345
432 4FZV SAM 5.64263
433 3TKY SAH 5.64263
434 1V59 FAD 5.64263
435 3HDY GDU 5.64263
436 3HDY FDA 5.64263
437 3HDY FAD 5.64263
438 5JCM FAD 5.64263
439 5JCM ISD 5.64263
440 5JCM NAD 5.64263
441 5FJN FAD 5.64263
442 5FJN BE2 5.64263
443 1Y8Q ATP 5.64263
444 1V59 NAD 5.64263
445 4OPC FDA 5.64263
446 6DEN G8A 5.64263
447 6DEN TP9 5.64263
448 6DEN FAD 5.64263
449 5X68 FAD 5.64263
450 6AIN FAD 5.64263
451 5M58 SAH 5.65217
452 4HXY NDP 5.93607
453 4DCM SAM 5.95611
454 3X0D SAH 5.95611
455 6C5B SAH 5.95611
456 4A6D SAM 5.95611
457 4MIG G3F 5.95611
458 5BRT FAD 5.95611
459 5BRT CH9 5.95611
460 4PNE SAH 5.96026
461 3DXY SAM 5.9633
462 5CUQ NSC 5.99251
463 3FZG SAM 6
464 1I9G SAM 6.07143
465 3EVG SAH 6.18182
466 4RDH AMP 6.25
467 1E6E FAD 6.25
468 4RDI ATP 6.25
469 1RPN NDP 6.26866
470 4DMG SAM 6.26959
471 5FUB SAH 6.26959
472 2Q7V FAD 6.26959
473 6ECT SAM 6.26959
474 2C5A NAD 6.26959
475 2C5A GDC 6.26959
476 3NKS FAD 6.26959
477 4CNK FAD 6.26959
478 5KOX FAD 6.26959
479 5KOX RFP 6.26959
480 5ZYN FAD 6.26959
481 2RAB FAD 6.26959
482 3DMH SAM 6.29921
483 3DMH GMP 6.29921
484 3CBG SAH 6.46552
485 5EJ2 NAD 6.49351
486 4D79 ATP 6.52174
487 2X2T GAL NGA 6.53595
488 4IWN GEK 6.55022
489 4JLS 3ZE 6.57895
490 5HJM MTA 6.58307
491 4Y30 49L 6.58307
492 4Y30 SAH 6.58307
493 5WGR FAD 6.58307
494 3NTD FAD 6.58307
495 2R4J FAD 6.58307
496 2R4J 13P 6.58307
497 4EMI NAD 6.58307
498 4EMI FAD 6.58307
499 3NT6 FAD 6.58307
500 5YEC ATP 6.58307
501 1BZL FAD 6.58307
502 5HZ7 BGC 6.58307
503 4GLL NAD 6.58307
504 3ACC 5GP 6.62983
505 5N5D SAM 6.63717
506 2P3V SRT 6.64062
507 2HNK SAH 6.69456
508 1XHL NDP 6.73401
509 3PFG TLO 6.84411
510 3PFG SAM 6.84411
511 5LOG SAH 6.86695
512 1ZEM NAD 6.87023
513 3OU2 SAH 6.88073
514 3GWZ SAH 6.89655
515 5X62 SAH 6.89655
516 3GXO SAH 6.89655
517 2WPF FAD 6.89655
518 2WPF WPF 6.89655
519 4BV6 FAD 6.89655
520 4CQM NAP 6.96721
521 1UAY ADN 7.02479
522 1RP0 AHZ 7.04225
523 2NXE SAM 7.08661
524 5K7U SAM 7.11111
525 3U4C NDP 7.11744
526 3TKA SAM 7.20461
527 5ERG SAM 7.21003
528 4GUT FAD 7.25806
529 4GUS FAD 7.25806
530 4HSU FAD 7.25806
531 3VZS CAA 7.393
532 3THR C2F 7.50853
533 5JCA FAD 7.52351
534 2RGO FAD 7.52351
535 5JCA NDP 7.52351
536 5Z75 NAD 7.52351
537 1NAA 6FA 7.52351
538 1NAA ABL 7.52351
539 5IL1 SAM 7.54717
540 2JBH 5GP 7.55556
541 1DL5 SAH 7.57098
542 3VC1 GST 7.69231
543 3VC1 SAH 7.69231
544 2AE2 NAP 7.69231
545 2AE2 PTO 7.69231
546 2PX8 SAH 7.80669
547 1L3I SAH 7.8125
548 5W7R SAH 7.83699
549 3GMB FAD 7.83699
550 2GAG NAD 8.08081
551 2GAG FAD 8.08081
552 5FWA J7C 8.15047
553 3AB1 FAD 8.15047
554 2GDZ NAD 8.2397
555 2OBF SAH 8.3045
556 2OBF F83 8.3045
557 3A25 SAM 8.30565
558 4L2I FAD 8.36502
559 5UFN SAH 8.40336
560 5YJI 8WO 8.4507
561 5YJI SAH 8.4507
562 4C4A SAH 8.46395
563 4KRG SAH 8.46395
564 1BC5 SAH 8.55019
565 4BLW AMP 8.65052
566 4BLW SAH 8.65052
567 2XVF FAD 8.77743
568 3LU1 NAD 8.77743
569 2YVF FAD 8.77743
570 2YVF NAD 8.77743
571 2O07 SPD 8.88158
572 4YUW 4JU 8.88158
573 4YUW S4M 8.88158
574 2O07 MTA 8.88158
575 5E9W SAH 8.97436
576 5GWT SIN 8.99281
577 5GWT NAD 8.99281
578 6MJ7 ARG 9.09091
579 4EIP FAD 9.09091
580 4D7E FAD 9.09091
581 4USR FAD 9.09091
582 3SJU NDP 9.319
583 3MB5 SAM 9.41177
584 4LWP SAH 9.71787
585 4AP3 NAP 9.71787
586 4AP3 FAD 9.71787
587 1NV8 MEQ 9.85915
588 1NV8 SAM 9.85915
589 3GDH SAH 9.95851
590 5BSZ SAH 10
591 2IID PHE 10.0313
592 2IID FAD 10.0313
593 3BXO SAM 10.0418
594 3LN9 FLC 10.0719
595 4XUC SAM 10.0917
596 4XUC 43G 10.0917
597 1QAN SAH 10.2459
598 5OC1 FAD 10.3448
599 2XG5 EC2 10.4046
600 2XG5 EC5 10.4046
601 3C3Y SAH 10.5485
602 4UCI SAM 10.6583
603 4RSL FAD 10.6583
604 3CH6 311 10.8392
605 3CH6 NAP 10.8392
606 1O5O U5P 10.8597
607 2WA2 SAM 10.8696
608 1JG3 ADN 11.0638
609 4NBU NAI 11.2
610 6ER9 NAP 11.2853
611 6ER9 FAD 11.2853
612 1QXA GLY GLY GLY 11.4894
613 4BJZ P3A 11.5987
614 4BJZ FAD 11.5987
615 6GAR FAD 11.5987
616 5E1M PRO PRO LYS ARG ILE ALA 11.6183
617 5E1M SAH 11.6183
618 5YJF SAH 11.6197
619 5YJF 8WO 11.6197
620 3EGI ADP 11.6505
621 6AM8 TRP 11.9122
622 5EEH P9P 11.9122
623 5EEH SAH 11.9122
624 3Q87 SAM 12.3529
625 2F5Z FAD 12.5
626 5KMS FAD 12.5392
627 5KMS NAD 12.5392
628 3GCZ SAM 12.766
629 1ELI PYC 12.8527
630 4RVG TYD 12.8527
631 4RVG SAM 12.8527
632 4YMH SAH 12.9167
633 1WY7 SAH 14.0097
634 4QTU SAM 14.0741
635 5MPT SAH 14.4201
636 5GM1 SAH 14.8148
637 4EMJ FAD 14.9533
638 2Q28 ADP 15.047
639 3AD8 NAD 15.1515
640 3AD8 FAD 15.1515
641 3AD8 PYC 15.1515
642 5ODQ FAD 16.3043
643 5TS5 FAD 16.9279
644 6DUB SAH 18.018
645 3ELW GP3 18.6667
646 3ELW SAM 18.6667
647 5JE0 SAH 20.2429
648 5JE0 AZ8 20.2429
649 5E8J SAH 20.4545
650 4POO SAM 28.5
651 2ZIF SAM 35.3535
Pocket No.: 2; Query (leader) PDB : 1NW5; Ligand: SAM; Similar sites found with APoc: 3
This union binding pocket(no: 2) in the query (biounit: 1nw5.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 2AWN ADP 2.19436
2 1U1I NAD 2.82132
3 4E70 N7I 5.01567
Pocket No.: 3; Query (leader) PDB : 1NW5; Ligand: SAM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1nw5.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
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