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Receptor
PDB id Resolution Class Description Source Keywords
1NN5 1.5 Å EC: 2.7.4.9 CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE KINASE WITH D4TMP + A HOMO SAPIENS THYMIDYLATE KINASE P-LOOP D4TMP TRANSFERASE
Ref.: STRUCTURES OF HUMAN THYMIDYLATE KINASE IN COMPLEX W PRODRUGS: IMPLICATIONS FOR THE STRUCTURE-BASED DESI NOVEL COMPOUNDS BIOCHEMISTRY V. 42 2568 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
2DT A:301;
 Valid;
 none;
 submit data
306.209 C10 H15 N2 O7 P CC1=C...
ANP A:303;
 Valid;
 none;
 submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:401;
A:402;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1NN5 1.5 Å EC: 2.7.4.9 CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE KINASE WITH D4TMP + A HOMO SAPIENS THYMIDYLATE KINASE P-LOOP D4TMP TRANSFERASE
Ref.: STRUCTURES OF HUMAN THYMIDYLATE KINASE IN COMPLEX W PRODRUGS: IMPLICATIONS FOR THE STRUCTURE-BASED DESI NOVEL COMPOUNDS BIOCHEMISTRY V. 42 2568 2003
Members (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 1E2Q - TMP C10 H15 N2 O8 P CC1=CN(C(=....
2 1E9C - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
3 1NN0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
4 1E2G - TMP C10 H15 N2 O8 P CC1=CN(C(=....
5 1NN1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
6 1NMX - FDM C10 H14 F N2 O7 P CC1=CN(C(=....
7 1E2E - AF3 Al F3 F[Al](F)F
8 1NN5 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
9 1E9B - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
10 1E2D - TMP C10 H15 N2 O8 P CC1=CN(C(=....
11 1E99 - ATM C10 H14 N5 O7 P CC1=CN(C(=....
12 1NMY - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
13 2XX3 - TAE C9 H14 N2 O8 P2 CC1=CN(C(=....
14 1NMZ - NYM C10 H16 N3 O7 P CC1=CN(C(=....
15 1E9D - ATM C10 H14 N5 O7 P CC1=CN(C(=....
16 1NN3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
17 1E9A - Z5A C20 H24 N10 O22 P5 CC1=CN(C(=....
18 1E9F - TMP C10 H15 N2 O8 P CC1=CN(C(=....
19 1E9E - TMP C10 H15 N2 O8 P CC1=CN(C(=....
20 1E98 - ATM C10 H14 N5 O7 P CC1=CN(C(=....
21 1E2F - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 1E2Q - TMP C10 H15 N2 O8 P CC1=CN(C(=....
2 1E9C - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
3 1NN0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
4 1E2G - TMP C10 H15 N2 O8 P CC1=CN(C(=....
5 1NN1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
6 1NMX - FDM C10 H14 F N2 O7 P CC1=CN(C(=....
7 1E2E - AF3 Al F3 F[Al](F)F
8 1NN5 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
9 1E9B - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
10 1E2D - TMP C10 H15 N2 O8 P CC1=CN(C(=....
11 1E99 - ATM C10 H14 N5 O7 P CC1=CN(C(=....
12 1NMY - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
13 2XX3 - TAE C9 H14 N2 O8 P2 CC1=CN(C(=....
14 1NMZ - NYM C10 H16 N3 O7 P CC1=CN(C(=....
15 1E9D - ATM C10 H14 N5 O7 P CC1=CN(C(=....
16 1NN3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
17 1E9A - Z5A C20 H24 N10 O22 P5 CC1=CN(C(=....
18 1E9F - TMP C10 H15 N2 O8 P CC1=CN(C(=....
19 1E9E - TMP C10 H15 N2 O8 P CC1=CN(C(=....
20 1E98 - ATM C10 H14 N5 O7 P CC1=CN(C(=....
21 1E2F - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (54)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2YOH Ki = 11 uM WMJ C17 H19 N5 O7 CC1=CN(C(=....
2 2YOF Ki = 25 uM 74W C18 H18 Cl F3 N4 O4 S CC1=CN(C(=....
3 2WWF - TMP C10 H15 N2 O8 P CC1=CN(C(=....
4 2YOG Ki = 31 uM 74X C18 H18 Cl F3 N4 O4 S CC1=CN(C(=....
5 2V54 - TYD C10 H16 N2 O11 P2 CC1=CN(C(=....
6 4QGF ic50 = 69 nM 32B C27 H30 Cl N3 O6 CC[C@H](c1....
7 4QG7 ic50 = 10 nM 32K C25 H26 Cl N3 O6 CC1=CN(C(=....
8 4QGH ic50 = 1 nM 32E C28 H31 Cl F N3 O5 CC1=CN(C(=....
9 4GFD Ki = 330 pM 0YB C29 H34 Br N3 O5 CC1=CN(C(=....
10 2CCJ - TMP C10 H15 N2 O8 P CC1=CN(C(=....
11 2CCG - TMP C10 H15 N2 O8 P CC1=CN(C(=....
12 4HDC ic50 = 1.2 nM 13Y C28 H32 Cl N3 O5 CC1=CN(C(=....
13 4HEJ ic50 = 24000 nM 14D C24 H24 F3 N3 O3 CC1=CN(C(=....
14 4GSY ic50 = 120 nM 0Y5 C25 H24 F3 N3 O5 CC1=CN(C(=....
15 4HLC ic50 = 174 nM T05 C24 H25 N3 O7 S Cc1cccc(c1....
16 4TMK Kd = 20 nM T5A C20 H30 N7 O23 P5 CC1=CN(C(=....
17 1E2Q - TMP C10 H15 N2 O8 P CC1=CN(C(=....
18 1E9C - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
19 1NN0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
20 1E2G - TMP C10 H15 N2 O8 P CC1=CN(C(=....
21 1NN1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
22 1NMX - FDM C10 H14 F N2 O7 P CC1=CN(C(=....
23 1E2E - AF3 Al F3 F[Al](F)F
24 1NN5 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
25 1E9B - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
26 1E2D - TMP C10 H15 N2 O8 P CC1=CN(C(=....
27 1E99 - ATM C10 H14 N5 O7 P CC1=CN(C(=....
28 1NMY - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
29 2XX3 - TAE C9 H14 N2 O8 P2 CC1=CN(C(=....
30 1NMZ - NYM C10 H16 N3 O7 P CC1=CN(C(=....
31 1E9D - ATM C10 H14 N5 O7 P CC1=CN(C(=....
32 1NN3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
33 1E9A - Z5A C20 H24 N10 O22 P5 CC1=CN(C(=....
34 1E9F - TMP C10 H15 N2 O8 P CC1=CN(C(=....
35 1E9E - TMP C10 H15 N2 O8 P CC1=CN(C(=....
36 1E98 - ATM C10 H14 N5 O7 P CC1=CN(C(=....
37 1E2F - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
38 2TMK - ATM C10 H14 N5 O7 P CC1=CN(C(=....
39 3TMK Kd = 135 nM T5A C20 H30 N7 O23 P5 CC1=CN(C(=....
40 1TMK - TMP C10 H15 N2 O8 P CC1=CN(C(=....
41 5X8C - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
42 5ZB4 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
43 5ZAX - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
44 5X86 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
45 5X8B - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
46 3UWO ic50 = 20 uM 0DJ C14 H12 N4 O2 CN1c2cc(cn....
47 3UXM ic50 = 17 uM 0DN C10 H13 F N2 O4 CC1=CN(C(=....
48 5UIV - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
49 5XB2 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
50 5XB3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
51 5XAI - TMP C10 H15 N2 O8 P CC1=CN(C(=....
52 5H56 - TYD C10 H16 N2 O11 P2 CC1=CN(C(=....
53 5H5B - FLC C6 H5 O7 C(C(=O)[O-....
54 5H5K - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 2DT; Similar ligands found: 30
No: Ligand ECFP6 Tc MDL keys Tc
1 2DT 1 1
2 D3T 0.75 0.985714
3 TMP 0.555556 0.971429
4 FDM 0.547945 0.931507
5 NYM 0.547945 0.944444
6 THP 0.540541 0.985507
7 ATM 0.525641 0.906667
8 DOC 0.506849 0.890411
9 T3P 0.5 0.957143
10 TYD 0.5 0.957747
11 D4M 0.486486 0.927536
12 DT DC 0.484848 0.868421
13 TTP 0.47561 0.957747
14 AZD 0.470588 0.894737
15 ATY 0.464286 0.931507
16 LLT 0.463768 0.833333
17 THM 0.463768 0.833333
18 TBD 0.451219 0.918919
19 0DN 0.430556 0.819444
20 AZZ 0.428571 0.789474
21 ABT 0.423913 0.871795
22 D4D 0.414634 0.914286
23 TLO 0.413043 0.905405
24 18T 0.410526 0.893333
25 TDX 0.410526 0.905405
26 1JB 0.410526 0.893333
27 TRH 0.410526 0.893333
28 DAU 0.40625 0.893333
29 T3F 0.402062 0.87013
30 T3Q 0.402062 0.87013
Ligand no: 2; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1NN5; Ligand: ANP; Similar sites found with APoc: 612
This union binding pocket(no: 1) in the query (biounit: 1nn5.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 3Q72 GNP None
2 5KSP GDP None
3 1S8F GDP None
4 1A4R GNH None
5 1KO8 6PG None
6 1A4R GDP None
7 1ZUI SKM None
8 2B8T THM None
9 3IIJ ADP None
10 3MJH GTP None
11 1YRB GDP 0.930233
12 1F9V ADP 0.930233
13 1YVD GNP 1.18343
14 1G6H ADP 1.39535
15 4KVA GTP 1.39535
16 2PL3 ADP 1.39535
17 1FP6 ADP 1.39535
18 1LVW TYD 1.39535
19 5H4S RAM 1.39535
20 2JAQ DCP 1.46341
21 2OBM ADP 1.86047
22 2OM2 GDP 1.86047
23 1Y3A GDP 1.86047
24 2OEM 1AE 1.86047
25 1SVK ALF GDP 1.86047
26 1BH2 GSP 1.86047
27 4R2I ANP 1.90476
28 4DID GDP 1.97368
29 2F9L GDP 2.01005
30 1OIV GDP 2.09424
31 2BME GNP 2.15054
32 1GXU 2HP 2.1978
33 4WOP CTP 2.22222
34 4C4P GNP 2.31214
35 3LRE ADP 2.32558
36 5TSH ANP 2.32558
37 5TSH ADP 2.32558
38 1XP8 AGS 2.32558
39 1XMV ADP 2.32558
40 5JCP GDP ALF 2.32558
41 1NY5 ADP 2.32558
42 1L2T ATP 2.32558
43 6DEF GCP 2.32558
44 2O0J ADP 2.32558
45 5G1N PAL 2.32558
46 1WF3 GNP 2.32558
47 6AU6 GDP 2.32558
48 1P3D ANP 2.32558
49 1EK0 GNP 2.35294
50 1R2Q GNP 2.35294
51 1JJV ATP 2.42718
52 3W5J GDP 2.45098
53 3UIE ANP 2.5
54 5N69 ADP 2.51256
55 1KMQ GNP 2.71739
56 1CXZ GSP 2.74725
57 4FRZ ADP 2.7907
58 2WHX ADP 2.7907
59 5CK5 GDP 2.7907
60 5ZXD ATP 2.7907
61 1V8K ANP 2.7907
62 2QEN ADP 2.7907
63 4P4T GDP 2.7907
64 2QZ4 ADP 2.7907
65 2JLR ANP 2.7907
66 4XGU ADP 2.7907
67 4FCW ADP 2.7907
68 4KBF AMP 2.7907
69 2J5V PCA 2.7907
70 3FVQ ATP 2.7907
71 4RZ3 ADP 2.7907
72 5K5Z ANP 2.7907
73 1OYY AGS 2.7907
74 1NST A3P 2.7907
75 1YVZ JPC 2.7907
76 3HQ9 OXL 2.7907
77 4XYM A12 2.7907
78 1T8U A3P 2.7907
79 6FOG OXL 2.7907
80 1BO4 COA 2.97619
81 3BC1 GNP 3.07692
82 2ZX2 RAM 3.07692
83 3BD9 A3P 3.21429
84 2AWN ADP 3.25581
85 1T5C ADP 3.25581
86 5M04 GDP 3.25581
87 1B0U ATP 3.25581
88 1DAR GDP 3.25581
89 3BOS CDP 3.25581
90 4LYA ATP 3.25581
91 1R6B ADP 3.25581
92 4PX9 ADP 3.25581
93 5XDR ADP 3.25581
94 1WDT GTP 3.25581
95 2XZ9 PYR 3.25581
96 3B7G ANP 3.25581
97 2VB6 ADP BEF 3.25581
98 4XSH GSP 3.25581
99 5JCZ GDP 3.25581
100 3RC3 ANP 3.25581
101 5X40 ACP 3.25581
102 2IXE ATP 3.25581
103 1IN4 ADP 3.25581
104 4LJ9 ACP 3.25581
105 4ITR GDP 3.25581
106 1CR1 TTP 3.25581
107 4PFO ADP 3.25581
108 2CHG ANP 3.25581
109 1F5N GNP 3.25581
110 3IUY AMP 3.25581
111 4LHD GLY 3.25581
112 2FH5 GTP 3.27103
113 4XOI GTP 3.33333
114 1RYH GNP 3.44828
115 3P4X ADP 3.63196
116 3LXR GDP 3.64583
117 1E96 GTP 3.64583
118 1OIX GDP 3.66492
119 3H4S ADP 3.7037
120 3COB ADP 3.72093
121 1KK1 GNP 3.72093
122 5GOE GDP 3.72093
123 4IEE AGS 3.72093
124 1G3Q ADP 3.72093
125 3EZ2 ADP 3.72093
126 5H7K GDP 3.72093
127 5H7J GCP 3.72093
128 3FWY ADP 3.72093
129 2D7D ADP 3.72093
130 1H65 GDP 3.72093
131 4NON GDP 3.72093
132 1CS4 GSP 3.72093
133 2GMV PEP 3.72093
134 1MH1 GNP 3.76344
135 2W2X GSP 3.78378
136 5J1J ANP 3.85965
137 2EFE GNH 3.8674
138 1GWN GTP 3.90244
139 5XC5 GTP 3.97727
140 2HV8 GTP 4.06977
141 5YV5 ADP 4.18605
142 1YQT ADP 4.18605
143 4D0N GDP 4.18605
144 4IHQ ADP 4.18605
145 5W75 GDP 4.18605
146 6G14 G4P 4.18605
147 4HSE ADP 4.18605
148 5FTB ANP 4.18605
149 2DPY ADP 4.18605
150 2CE7 ADP 4.18605
151 4R43 GDP 4.18605
152 3TBK ANP 4.18605
153 2ZTS ADP 4.18605
154 1E2K TMC 4.18605
155 5FHD ADP ALF 4.18605
156 5MZN ADP 4.18605
157 4TTQ ATP 4.18605
158 1K6M AGS 4.18605
159 1ION ADP 4.18605
160 6B4K ANP 4.18605
161 1NJF ADP 4.18605
162 5M7P ADP 4.18605
163 4ZDJ UTP 4.18605
164 5IRR GSP 4.18605
165 1FNN ADP 4.18605
166 4YC7 GNP 4.18605
167 4NCN GTP 4.18605
168 4TMZ GSP 4.18605
169 1NJF AGS 4.18605
170 2GN2 C5P 4.18605
171 4ZKD GDP 4.18605
172 5I34 GDP 4.18605
173 4G86 BNT 4.18605
174 2ZE7 DST 4.18605
175 4KVG GTP 4.18605
176 5J1S ATP 4.18605
177 2D7C GTP 4.19162
178 5UQW GDP 4.2328
179 3SBD GNP 4.27807
180 1M7B GTP 4.34783
181 5LB3 ADP 4.65116
182 5Y6N ADP 4.65116
183 5IFS ADP 4.65116
184 1OE0 TTP 4.65116
185 4JLV ADP 4.65116
186 5HPY GDP 4.65116
187 2FSH ANP 4.65116
188 1TQ4 GDP 4.65116
189 1OS1 PYR 4.65116
190 1OS1 ATP 4.65116
191 3KJI ADP 4.65116
192 4D81 ADP 4.65116
193 3HU3 AGS 4.65116
194 3KC1 2T6 4.65116
195 4WZA ACP 4.65116
196 4NE2 ADP 4.65116
197 4NE2 SH2 4.65116
198 4WZA ADP 4.65116
199 1J3I UMP 4.65116
200 3QKT ANP 4.65116
201 1NF3 GNP 4.6875
202 4KFU ACP 4.71698
203 1Z2A GDP 4.7619
204 2ZEJ GDP 4.8913
205 1GRN GDP 4.92611
206 5E5U MLI 5.02513
207 1TX4 ALF GDP 5.05051
208 1Z0J GTP 5.08475
209 2PZE ATP 5.11628
210 2VVG ADP 5.11628
211 4WZ6 ATP 5.11628
212 3EWA ANP 5.11628
213 4R98 GNH 5.11628
214 5KSZ GCP 5.11628
215 4M9Q GNP 5.11628
216 3FKQ ATP 5.11628
217 1OW3 GDP 5.11628
218 5VHC BEF ADP 5.11628
219 3DZD ADP 5.11628
220 2XTZ GSP 5.11628
221 3BFX A3P 5.11628
222 2J0V GDP 5.18868
223 3H86 AP5 5.20833
224 2A5J GDP 5.2356
225 4JLS 3ZE 5.26316
226 5E95 GDP 5.35714
227 1KAO GDP 5.38922
228 1CLU DBG 5.42169
229 2QG6 NMN 5.52764
230 3CNL GNP 5.5814
231 4DCT GDP 5.5814
232 3E70 GDP 5.5814
233 5LTJ ADP 5.5814
234 5LTJ BEF 5.5814
235 4GOX A3P 5.5814
236 1GQY ACP 5.5814
237 1WQ1 GDP 5.5814
238 2GWH A3P 5.5814
239 3REF GDP 5.6701
240 3DEF GDP 5.72519
241 1ZJ6 G3D 5.88235
242 5O2T GSP 5.88235
243 1M6P M6P 5.92105
244 1HE1 GDP 5.92593
245 1JJ7 ADP 6.04651
246 2KIN ADP 6.04651
247 2XT3 ADP 6.04651
248 5FG3 GDP 6.04651
249 1MKY GDP 6.04651
250 5YT0 GDP 6.04651
251 4LPS GDP 6.04651
252 3GJ4 GDP 6.04651
253 1VKJ A3P 6.04651
254 2GDJ ANP 6.04651
255 3GJ8 GDP 6.04651
256 3GJ5 GDP 6.04651
257 5BN3 ADP 6.04651
258 5Z69 AGS 6.04651
259 2OZE AGS 6.04651
260 3CPJ GDP 6.04651
261 2XAU ADP 6.04651
262 4RD0 GDP 6.04651
263 2BCG GDP 6.04651
264 5I0H ADP BEF 6.04651
265 5E9G GLV 6.04651
266 2C9O ADP 6.04651
267 3FYH ADP 6.04651
268 6D3U 83Y BDP 83Y GCD 6.04651
269 6CS8 F9Y 6.04651
270 1D2N ANP 6.04651
271 3ZQ6 ADP ALF 6.04651
272 2Q8M AMP 6.04651
273 2BEK ATP 6.04651
274 5O74 GDP 6.09137
275 1YZG GDP 6.14525
276 1QF9 C5P 6.18557
277 1QF9 ADP 6.18557
278 1QF9 ALF 6.18557
279 1XX6 ADP 6.28272
280 1XPJ TLA 6.34921
281 3DWQ NGC GAL NGA POL AZI 6.34921
282 1G16 GDP 6.47059
283 3RAB GNP 6.50888
284 1GOJ ADP 6.51163
285 4YMU ATP 6.51163
286 1AKY AP5 6.51163
287 1D2E GDP 6.51163
288 5W7Q GDP 6.51163
289 2RCN GDP 6.51163
290 1G7S GDP 6.51163
291 5HCN GCP 6.51163
292 4MKF AP5 6.51163
293 5HR5 ADP 6.51163
294 2G77 GDP 6.51163
295 2C77 GNP 6.51163
296 4ZG4 VO4 ADP 6.51163
297 2C78 GNP 6.51163
298 1G4U GDP 6.51163
299 2G77 AF3 6.51163
300 2HF9 GSP 6.51163
301 4PJ3 ANP 6.51163
302 1IHU AF3 6.51163
303 3VMF GTP 6.51163
304 3WXM GTP 6.51163
305 1IHU ADP 6.51163
306 3VX3 ADP 6.51163
307 2GKS ADP 6.51163
308 1UJ2 ADP 6.51163
309 1UJ2 C5P 6.51163
310 5OEC GDP 6.55738
311 5TB5 GDP 6.66667
312 5TAR GDP 6.75676
313 5KDO GDP 6.75676
314 1M2O GNP 6.84211
315 5OCG GNP 6.87831
316 1UKZ ADP 6.89655
317 2WJG GDP 6.91489
318 1RRC ADP 6.97674
319 3A4M ADP 6.97674
320 4U00 ADP 6.97674
321 5G41 AP5 6.97674
322 3FB4 AP5 6.97674
323 1ZIN AP5 6.97674
324 4MKG AP5 6.97674
325 6A20 ADP 6.97674
326 3B5J 12D 6.97674
327 4Q1A 2XZ 6.97674
328 4Q1A UDP 6.97674
329 1U0J ADP 6.97674
330 5IRN ADP 6.97674
331 5ZBR ANP 6.97674
332 6B8B ADP 6.97674
333 2B8W ALF 5GP 6.97674
334 2WHP HI6 6.97674
335 5DHF GNP 6.97674
336 5DIF GNP 6.97674
337 5UWT GNP 6.97674
338 5UWU GNP 6.97674
339 5UWQ GNP 6.97674
340 5UWH GNP 6.97674
341 5UWO GNP 6.97674
342 5UWJ GNP 6.97674
343 6CIT GNP 6.97674
344 5UWI GNP 6.97674
345 5UWR GNP 6.97674
346 1KSH GDP 6.98925
347 4UXH T5A 7.06522
348 1F6B GDP 7.07071
349 3T1O GDP 7.07071
350 4QRH 0O2 7.14286
351 2WJH GDP 7.22892
352 2WJH FLC 7.22892
353 4D0G GTP 7.24638
354 6BC0 GSP 7.33333
355 5BQ5 ADP BEF 7.40741
356 4GOJ GNP 7.40741
357 1OXV ANP 7.44186
358 5W76 GDP 7.44186
359 3BFV ADP 7.44186
360 2NGR GDP 7.44186
361 3DKP ADP 7.44186
362 4HI0 GDP 7.44186
363 1X6V ADP 7.44186
364 4H1V GNP 7.44186
365 6H5E ANP 7.44186
366 5HV7 RBL 7.44186
367 1DAK ADP 7.44186
368 1DAK DPU 7.44186
369 2GCO GNP 7.46269
370 2GCN GDP 7.46269
371 1I4D GDP 7.58929
372 1Z83 AP5 7.65306
373 1KY3 GDP 7.69231
374 1B7T ADP 7.69231
375 2OFW ADX 7.69231
376 1FZQ GDP 7.73481
377 5L3W GDP 7.90698
378 4YJ1 ADP 7.90698
379 5VGR GDP 7.90698
380 3AB3 GDP 7.90698
381 1ZCB GDP 7.90698
382 3Q9L ATP 7.90698
383 3CX8 GSP 7.90698
384 1YTM ATP 7.90698
385 4HE2 AMP 7.90698
386 3T12 GDP ALF 8.08823
387 3GJ7 GDP 8.16327
388 4QM7 GTP 8.18713
389 1SVI GDP 8.20513
390 3KTA AP5 8.24176
391 2VOH CIT 8.28025
392 1SQ5 ADP 8.37209
393 3GJ3 GDP 8.37209
394 3GJ0 GDP 8.37209
395 5BXQ GDP 8.37209
396 3CH5 GDP 8.37209
397 1IBR GNP 8.37209
398 1Z06 GNP 8.46561
399 1R4A GNP 8.48485
400 2ODE ALF GDP 8.51064
401 4BQS K2Q 8.52273
402 4BQS ADP 8.52273
403 1M7G AV2 8.53081
404 1M7G ADP 8.53081
405 1M7G ADX 8.53081
406 2HT6 GDP 8.62069
407 3RWO GDP 8.64865
408 3TKL GTP 8.67347
409 2CBZ ATP 8.83721
410 4AG5 ADP 8.83721
411 2WIC GNP 8.83721
412 4ZNL BEF ADP 8.83721
413 2WMO GTP 8.83721
414 1NRJ GTP 8.83721
415 1GOT GDP 8.83721
416 2FAH GDP 8.83721
417 5EXT ADP 8.83721
418 4K81 GTP 8.83721
419 4YS0 ADP 8.83721
420 1Q19 SSC 8.83721
421 1DS6 GDP 8.88889
422 1Z0F GDP 8.93855
423 2CDN ADP 8.95522
424 5IRC GDP 8.95522
425 1VHT BA3 9.17431
426 2OG2 MLI 9.30233
427 3NHB ADP 9.30233
428 3B9Q MLI 9.30233
429 2IYL GDP 9.30233
430 3EC1 GDP 9.30233
431 1Z6T ADP 9.30233
432 5LLB 6YZ 9.30233
433 2GK6 ADP 9.30233
434 2BIF SIN 9.30233
435 1RJ9 GCP 9.30233
436 2BIF ANP 9.30233
437 1QHG ATP 9.30233
438 3SFV GDP 9.39227
439 6BYF CIT 9.41177
440 4U5X GNP 9.55056
441 3M1I GTP 9.58904
442 1VG0 GDP 9.66184
443 1VG8 GNP 9.66184
444 3NKV GNP 9.71429
445 4LC1 GDP 9.76744
446 4QOS ADP 9.76744
447 2FNA ADP 9.76744
448 2ORV 4TA 9.76744
449 3KUD GDP 9.87654
450 6BCA GSP 9.93377
451 2EW1 GNP 9.95025
452 2PEZ GGZ 10.0559
453 2PEZ DAT 10.0559
454 1ZD9 GDP 10.1064
455 5U32 GDP 10.2326
456 2QN6 GDP 10.2326
457 4YDS ATP 10.2326
458 2IS6 ADP 10.2326
459 1PUJ GNP 10.2326
460 5GVR LMR 10.2326
461 1P72 ADP 10.2326
462 4A4Z ANP 10.2326
463 5L3R GCP 10.2326
464 6FAA ADP 10.2326
465 1LVK MNT BEF 10.2326
466 2QQ0 THM 10.3261
467 2QQ0 ADP 10.3261
468 2QQ0 TMP 10.3261
469 2QQ0 ANP 10.3261
470 5UPK GNP 10.4167
471 5MVR ADP 10.4938
472 3T5G GDP 10.4972
473 6BSX GDP 10.6742
474 6BSX E7S 10.6742
475 2D2F ADP 10.6977
476 1G6O ADP 10.6977
477 3ZFD ANP 10.6977
478 3IO3 ADP 10.6977
479 2FJU GSP 10.6977
480 4XTR ADP 10.6977
481 1W5T ANP 10.6977
482 4XTR ATP 10.6977
483 4XVU ATP 10.6977
484 1W5T ADP 10.6977
485 1HTW ADP 10.7595
486 1W4R TTP 10.7692
487 1VG1 GDP 10.8108
488 1VG9 GDP 10.8108
489 2A5F GTP 10.8571
490 1Z0A GDP 10.9195
491 3PCR GTP 11.1111
492 1XKV ATP 11.1628
493 1R0X ATP 11.1628
494 1GP2 GDP 11.2676
495 5Z2M GTP 11.3636
496 2W58 ADP 11.3861
497 1TU3 GNP 11.3924
498 2W83 GTP 11.5152
499 2NCD ADP 11.6279
500 2Y65 ADP 11.6279
501 3MD0 GDP 11.6279
502 4BFW ZVW 11.6279
503 1SVM ATP 11.6279
504 5KUT GDP 11.6402
505 6BCB GSP 11.6438
506 2FFQ GSP 11.6959
507 3N5C GDP 11.7284
508 1D5C GDP 11.7284
509 2J59 GTP 12.0482
510 1O3Y GTP 12.0482
511 3DC4 ADP 12.093
512 2ZFI ADP 12.093
513 2XTN GTP 12.093
514 2WKQ GTP 12.093
515 1RE0 GDP 12.1951
516 1S9D GDP 12.1951
517 1KK8 BEF ADP 12.2302
518 1BG2 ADP 12.5581
519 3TK1 GDP 12.5581
520 1G41 ADP 12.5581
521 1OFH ADP 12.5581
522 5AK0 8V1 12.5581
523 3ZIA ATP 12.6984
524 3ZIA ADP 12.6984
525 3A1S GDP 12.7907
526 3PQC GDP 12.8205
527 2A9K GDP 12.8342
528 4J0Q GDP 13.0233
529 1W7J ADP BEF 13.0233
530 4V03 ADP 13.0233
531 1QHH ATP 13.0435
532 2UZI GTP 13.1579
533 3QF7 ANP 13.4884
534 1FQJ GDP 13.6054
535 1FQK GDP 13.6054
536 1FQK ALF 13.6054
537 4KAX GTP 13.6095
538 4V0K GDP 13.6095
539 4CVN ADP 13.6126
540 1UAD GNP 13.7143
541 1ZC3 GNP 13.7143
542 1MR3 G3D 13.8122
543 4YLG GDP 13.8728
544 6CRK GDP 13.9535
545 1UPT GTP 14.0351
546 4BAS GNP 14.0704
547 2X77 GDP 14.2857
548 4ZI2 GNP 14.2857
549 1U8Z GDP 14.2857
550 1G7C 5GP 14.4186
551 2RGX AP5 14.5631
552 5EE5 GTP 14.6199
553 4J6W C 14.6341
554 3AQ4 GDP 14.6739
555 3Q85 GNP 14.7929
556 4DKX GDP 14.8837
557 3WYA GDP 14.8837
558 3WY9 GDP 14.8837
559 4CQK PIO 14.8936
560 1LVG ADP 15.1515
561 4PPF FLC 15.3488
562 2ZR9 DTP 15.3488
563 1J2J GTP 15.5556
564 2CJW GDP 15.625
565 4E03 ADP 16.0194
566 4B47 GDP 16.2791
567 2V7Q ATP 16.2791
568 2CK3 ANP 16.2791
569 1W0J ADP 16.2791
570 2V7Q ADP 16.2791
571 1W0J ADP BEF 16.2791
572 2CK3 ADP 16.2791
573 5WC2 ADP 16.7442
574 5LEF GTP 16.7539
575 5G3Y ADP 17.2093
576 5WLB GNP 17.6471
577 5L3V GDP 17.6744
578 5L3S G 17.6744
579 5L3S GNP 17.6744
580 4X8O AP5 17.757
581 2Y8E GNP 17.8771
582 1SKQ GDP 18.1395
583 4NU0 AP5 18.1395
584 1S3G AP5 18.1395
585 3RLF ANP 18.1395
586 3QBT GNP 18.3908
587 4LHW GNP 18.3908
588 3U6B GDP 18.6047
589 2HCJ GDP 18.6047
590 4P3Y GDP 18.6047
591 5JBQ GDP 18.6047
592 1D8T GDP 18.6047
593 4G5G GDP 18.6047
594 3U6K GDP 18.6047
595 2BVN GNP 18.6047
596 4PC3 GDP 18.6047
597 1YZQ GNP 19.4118
598 1JI0 ATP 19.5349
599 4WEI GLC GAL 19.5349
600 6C90 ADP 20
601 1Z0K GTP 20.2899
602 2GJ8 ALF GDP 20.9302
603 4OI4 ATP 20.9302
604 1Y63 ADP 21.1957
605 2G3F IZC 21.3953
606 3T34 GDP 21.8605
607 5DI3 GNP 22.3256
608 1Z08 GNP 22.3529
609 3QXC ATP 23.2558
610 1I7A PHE 24.3243
611 2QTV GNP 36.7347
612 3DOE GTP 36.9792
Pocket No.: 2; Query (leader) PDB : 1NN5; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1nn5.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1NN5; Ligand: 2DT; Similar sites found with APoc: 612
This union binding pocket(no: 3) in the query (biounit: 1nn5.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 3Q72 GNP None
2 5KSP GDP None
3 1S8F GDP None
4 1A4R GNH None
5 1KO8 6PG None
6 1A4R GDP None
7 1ZUI SKM None
8 2B8T THM None
9 3IIJ ADP None
10 3MJH GTP None
11 1YRB GDP 0.930233
12 1F9V ADP 0.930233
13 1YVD GNP 1.18343
14 1G6H ADP 1.39535
15 4KVA GTP 1.39535
16 2PL3 ADP 1.39535
17 1FP6 ADP 1.39535
18 1LVW TYD 1.39535
19 5H4S RAM 1.39535
20 2JAQ DCP 1.46341
21 2OBM ADP 1.86047
22 2OM2 GDP 1.86047
23 1Y3A GDP 1.86047
24 2OEM 1AE 1.86047
25 1SVK ALF GDP 1.86047
26 1BH2 GSP 1.86047
27 4R2I ANP 1.90476
28 4DID GDP 1.97368
29 2F9L GDP 2.01005
30 1OIV GDP 2.09424
31 2BME GNP 2.15054
32 1GXU 2HP 2.1978
33 4WOP CTP 2.22222
34 4C4P GNP 2.31214
35 3LRE ADP 2.32558
36 5TSH ANP 2.32558
37 5TSH ADP 2.32558
38 1XP8 AGS 2.32558
39 1XMV ADP 2.32558
40 5JCP GDP ALF 2.32558
41 1NY5 ADP 2.32558
42 1L2T ATP 2.32558
43 6DEF GCP 2.32558
44 2O0J ADP 2.32558
45 5G1N PAL 2.32558
46 1WF3 GNP 2.32558
47 6AU6 GDP 2.32558
48 1P3D ANP 2.32558
49 1EK0 GNP 2.35294
50 1R2Q GNP 2.35294
51 1JJV ATP 2.42718
52 3W5J GDP 2.45098
53 3UIE ANP 2.5
54 5N69 ADP 2.51256
55 1KMQ GNP 2.71739
56 1CXZ GSP 2.74725
57 4FRZ ADP 2.7907
58 2WHX ADP 2.7907
59 5CK5 GDP 2.7907
60 5ZXD ATP 2.7907
61 1V8K ANP 2.7907
62 2QEN ADP 2.7907
63 4P4T GDP 2.7907
64 2QZ4 ADP 2.7907
65 2JLR ANP 2.7907
66 4XGU ADP 2.7907
67 4FCW ADP 2.7907
68 4KBF AMP 2.7907
69 2J5V PCA 2.7907
70 3FVQ ATP 2.7907
71 4RZ3 ADP 2.7907
72 5K5Z ANP 2.7907
73 1OYY AGS 2.7907
74 1NST A3P 2.7907
75 1YVZ JPC 2.7907
76 3HQ9 OXL 2.7907
77 4XYM A12 2.7907
78 1T8U A3P 2.7907
79 6FOG OXL 2.7907
80 1BO4 COA 2.97619
81 3BC1 GNP 3.07692
82 2ZX2 RAM 3.07692
83 3BD9 A3P 3.21429
84 2AWN ADP 3.25581
85 1T5C ADP 3.25581
86 5M04 GDP 3.25581
87 1B0U ATP 3.25581
88 1DAR GDP 3.25581
89 3BOS CDP 3.25581
90 4LYA ATP 3.25581
91 1R6B ADP 3.25581
92 4PX9 ADP 3.25581
93 5XDR ADP 3.25581
94 1WDT GTP 3.25581
95 2XZ9 PYR 3.25581
96 3B7G ANP 3.25581
97 2VB6 ADP BEF 3.25581
98 4XSH GSP 3.25581
99 5JCZ GDP 3.25581
100 3RC3 ANP 3.25581
101 5X40 ACP 3.25581
102 2IXE ATP 3.25581
103 1IN4 ADP 3.25581
104 4LJ9 ACP 3.25581
105 4ITR GDP 3.25581
106 1CR1 TTP 3.25581
107 4PFO ADP 3.25581
108 2CHG ANP 3.25581
109 1F5N GNP 3.25581
110 3IUY AMP 3.25581
111 4LHD GLY 3.25581
112 2FH5 GTP 3.27103
113 4XOI GTP 3.33333
114 1RYH GNP 3.44828
115 3P4X ADP 3.63196
116 3LXR GDP 3.64583
117 1E96 GTP 3.64583
118 1OIX GDP 3.66492
119 3H4S ADP 3.7037
120 3COB ADP 3.72093
121 1KK1 GNP 3.72093
122 5GOE GDP