-->
Receptor
PDB id Resolution Class Description Source Keywords
1NF3 2.1 Å EC: 3.-.-.- STRUCTURE OF CDC42 IN A COMPLEX WITH THE GTPASE-BINDING DOMAIN OF THE CELL POLARITY PROTEIN, PAR6 HOMO SAPIENS SEMI-CRIB MOTIF SWITCH I AND II PDZ DOMAIN GTPASE BINDING DOMAIN SIGNALING PROTEIN
Ref.: STRUCTURE OF CDC42 IN A COMPLEX WITH THE GTPASE-BINDING DOMAIN OF THE CELL POLARITY PROTEIN, PAR6 EMBO J. V. 22 1125 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GNP A:200;
B:202;
Valid;
Valid;
none;
none;
Kd = 50 nM
522.196 C10 H17 N6 O13 P3 c1nc2...
MG A:201;
B:203;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1NF3 2.1 Å EC: 3.-.-.- STRUCTURE OF CDC42 IN A COMPLEX WITH THE GTPASE-BINDING DOMAIN OF THE CELL POLARITY PROTEIN, PAR6 HOMO SAPIENS SEMI-CRIB MOTIF SWITCH I AND II PDZ DOMAIN GTPASE BINDING DOMAIN SIGNALING PROTEIN
Ref.: STRUCTURE OF CDC42 IN A COMPLEX WITH THE GTPASE-BINDING DOMAIN OF THE CELL POLARITY PROTEIN, PAR6 EMBO J. V. 22 1125 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 1NF3 Kd = 50 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1NF3 Kd = 50 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 173 families.
1 1NF3 Kd = 50 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GNP; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 9GM 1 1
3 GDP 0.839506 0.973684
4 GP3 0.82716 0.948718
5 GTP 0.809524 0.973684
6 GNH 0.807229 0.986842
7 G1R 0.77907 0.961039
8 GCP 0.77907 0.948718
9 GSP 0.770115 0.925
10 5GP 0.756098 0.960526
11 G 0.756098 0.960526
12 G2R 0.747253 0.936709
13 GMV 0.747126 0.948718
14 GAV 0.714286 0.936709
15 GP2 0.712644 0.936709
16 G2P 0.711111 0.936709
17 Y9Z 0.708333 0.880952
18 GDC 0.690722 0.936709
19 GDD 0.690722 0.936709
20 GKE 0.690722 0.936709
21 G5P 0.686869 0.948718
22 GPG 0.684211 0.936709
23 GTG 0.683673 0.91358
24 GDR 0.683673 0.936709
25 GFB 0.683673 0.936709
26 JB2 0.68 0.936709
27 GKD 0.68 0.936709
28 6CK 0.676768 0.91358
29 G3A 0.676768 0.948718
30 GDX 0.673267 0.948718
31 ALF 5GP 0.67033 0.86747
32 YGP 0.663265 0.879518
33 GPD 0.656863 0.902439
34 ALF GDP 0.645833 0.86747
35 GDP AF3 0.645833 0.86747
36 GDP ALF 0.645833 0.86747
37 JB3 0.641509 0.925
38 DBG 0.640351 0.974359
39 G3D 0.638298 0.960526
40 G4P 0.625 0.960526
41 GMP 0.621951 0.857143
42 NGD 0.62037 0.936709
43 GGM 0.618182 0.925926
44 0O2 0.616162 0.960526
45 2MD 0.603604 0.870588
46 CAG 0.60177 0.904762
47 U2G 0.590909 0.91358
48 FEG 0.590909 0.858824
49 GDP 7MG 0.590476 0.888889
50 MGD 0.587719 0.870588
51 G G 0.586538 0.924051
52 ZGP 0.585586 0.848837
53 CG2 0.580357 0.91358
54 ANP 0.568421 0.922078
55 PGD 0.567797 0.902439
56 MD1 0.567797 0.870588
57 3GP 0.56044 0.922078
58 TPG 0.558333 0.822222
59 GH3 0.55 0.948052
60 FE9 0.546219 0.778947
61 GPX 0.539216 0.922078
62 G4M 0.539062 0.860465
63 DGI 0.536082 0.9
64 BGO 0.535088 0.901235
65 IDP 0.53125 0.947368
66 DGT 0.53 0.9
67 2GP 0.526882 0.935065
68 G1R G1R 0.520325 0.901235
69 GCP G 0.518868 0.897436
70 A G 0.516949 0.911392
71 U A G G 0.512605 0.911392
72 G A A A 0.504202 0.9
73 AGO 0.504202 0.91358
74 P2G 0.5 0.860759
75 G1G 0.5 0.902439
76 R7I 0.49505 0.922078
77 MGP 0.49505 0.936709
78 R5I 0.49505 0.922078
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 AKW 0.483051 0.869048
83 DG 0.474227 0.8875
84 DGP 0.474227 0.8875
85 G U 0.466667 0.878049
86 IMP 0.463918 0.934211
87 G2Q 0.462963 0.936709
88 GPC 0.459677 0.858824
89 G C 0.459016 0.878049
90 GTA 0.448276 0.91358
91 G7M 0.444444 0.924051
92 MAP 0.439252 0.898734
93 G G G RPC 0.435484 0.853659
94 B4P 0.434343 0.871795
95 AP5 0.434343 0.871795
96 ADP 0.434343 0.896104
97 A2D 0.43299 0.871795
98 AT4 0.43 0.8625
99 G G G C 0.426357 0.890244
100 AU1 0.425743 0.922078
101 SGP 0.425743 0.807229
102 BA3 0.424242 0.871795
103 A G C C 0.423077 0.888889
104 35G 0.423077 0.909091
105 PCG 0.423077 0.909091
106 C2E 0.423077 0.897436
107 APC G U 0.421875 0.864198
108 HEJ 0.421569 0.896104
109 ATP 0.421569 0.896104
110 ACQ 0.419048 0.873418
111 5GP 5GP 0.419048 0.860759
112 5FA 0.417476 0.896104
113 AQP 0.417476 0.896104
114 01G 0.417391 0.880952
115 AN2 0.415842 0.909091
116 UNP 0.415842 0.810127
117 6AD 0.415094 0.821429
118 M33 0.411765 0.860759
119 ITT 0.411765 0.846154
120 G C C C 0.410448 0.901235
121 HFD 0.409524 0.851852
122 G U34 0.408 0.86747
123 ACP 0.407767 0.873418
124 6YZ 0.407407 0.873418
125 AR6 0.403846 0.871795
126 APR 0.403846 0.871795
127 DG DG 0.403509 0.845238
128 A4P 0.403226 0.848837
129 UCG 0.402985 0.888889
130 SAP 0.4 0.851852
131 AGS 0.4 0.851852
132 AD9 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1NF3; Ligand: GNP; Similar sites found with APoc: 585
This union binding pocket(no: 1) in the query (biounit: 1nf3.bio3) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1TU3 GNP None
2 1R2Q GNP None
3 5O96 SAM 2.05128
4 1SQL GUN 2.05479
5 2VOH CIT 2.34375
6 2XT3 ADP 2.5641
7 4JLV ADP 3.07692
8 2GWH A3P 3.07692
9 4YDS ATP 3.125
10 2RGX AP5 3.125
11 1QAN SAH 3.125
12 3FKQ ATP 3.58974
13 1DAK DPU 3.58974
14 1DAK ADP 3.58974
15 3UIE ANP 3.58974
16 4X17 SIA SIA 3.58974
17 3IO3 ADP 3.90625
18 4PU6 ASP 3.90625
19 3A4M ADP 4.10256
20 5ZXD ATP 4.10256
21 3FVQ ATP 4.10256
22 4NTO 1PW 4.10256
23 5J6Y GLC 4.25532
24 5J6Y BGC 4.25532
25 3DZD ADP 4.61538
26 4IDN GNP 4.61538
27 3DKP ADP 4.61538
28 5YLF BGC 4.61538
29 2FHE GSH 4.61538
30 2W58 ADP 4.6875
31 3ZFD ANP 4.6875
32 5BQ5 ADP BEF 4.6875
33 4D81 ADP 4.6875
34 2ZTS ADP 4.6875
35 1IN4 ADP 4.6875
36 4Y4V DAL 4.6875
37 3DC4 ADP 4.6875
38 4U60 SIA GAL NGA 4.6875
39 3GD8 GOL 4.6875
40 4U60 SIA 4.6875
41 5WC2 ADP 4.6875
42 1D2N ANP 4.6875
43 6B8B ADP 4.6875
44 4MZQ 1VU 4.6875
45 1NN5 2DT 4.6875
46 1NN5 ANP 4.6875
47 2JBH 5GP 4.6875
48 4BQS ADP 5.11364
49 4BQS K2Q 5.11364
50 2FH5 GTP 5.12821
51 5U32 GDP 5.12821
52 4NON GDP 5.12821
53 2OBM ADP 5.12821
54 1YTM ATP 5.12821
55 1F9V ADP 5.12821
56 1QFT HSM 5.14286
57 5EE5 GTP 5.26316
58 2AWN ADP 5.46875
59 3A1S GDP 5.46875
60 2CBZ ATP 5.46875
61 1M7G AV2 5.46875
62 1HTW ADP 5.46875
63 2WIC GNP 5.46875
64 3CNL GNP 5.46875
65 4OHY ANP 5.46875
66 6B4K ANP 5.46875
67 1IHU AF3 5.46875
68 1IHU ADP 5.46875
69 5L3V GDP 5.46875
70 1M7G ADX 5.46875
71 1M7G ADP 5.46875
72 4IOK XPO 5.46875
73 4QRH 0O2 5.46875
74 4IOK ADP 5.46875
75 4UOX PUT 5.46875
76 4UOX PLP 5.46875
77 1T5C ADP 5.46875
78 3COB ADP 5.64103
79 2PZE ATP 5.64103
80 4WZ6 ATP 5.64103
81 5LB3 ADP 5.64103
82 1R0X ATP 5.64103
83 1OS1 PYR 5.64103
84 1OS1 ATP 5.64103
85 4OI4 ATP 6.08696
86 2WHX ADP 6.15385
87 5I34 GDP 6.15385
88 4IEE AGS 6.15385
89 5M7P ADP 6.15385
90 2J0W ASP 6.15385
91 1NST A3P 6.15385
92 3ITJ CIT 6.15385
93 2JLR ANP 6.15385
94 4J0Q GDP 6.25
95 2KIN ADP 6.25
96 1BG2 ADP 6.25
97 5ZBR ANP 6.25
98 3B5J 12D 6.25
99 1U0J ADP 6.25
100 1IWE IMP 6.25
101 2D7D ADP 6.25
102 3FSY SCA 6.25
103 5VHC BEF ADP 6.25
104 5IRN ADP 6.25
105 1G8S MET 6.25
106 1I1N SAH 6.25
107 3AI8 HNQ 6.25
108 1UH4 GLC 6.25
109 3SI2 PBD 6.25
110 1XX6 ADP 6.28272
111 5HCN GCP 6.66667
112 1DAR GDP 6.66667
113 5FTB ANP 6.66667
114 3T34 GDP 6.66667
115 1NJF ADP 6.66667
116 5FHD ADP ALF 6.66667
117 1NJF AGS 6.66667
118 5TQZ GLC 6.66667
119 4YMU ATP 7.03125
120 3EZ2 ADP 7.03125
121 1B7T ADP 7.03125
122 2CDN ADP 7.03125
123 4V03 ADP 7.03125
124 4R43 GDP 7.03125
125 1RJ9 GCP 7.03125
126 5GOE GDP 7.03125
127 4XGU ADP 7.03125
128 4R98 GNH 7.03125
129 1W7J ADP BEF 7.03125
130 5IFS ADP 7.03125
131 1KK8 BEF ADP 7.03125
132 5MZN ADP 7.03125
133 2ZUX RAM 7.03125
134 4HSE ADP 7.03125
135 3L6C MLI 7.03125
136 4MKF AP5 7.03125
137 2IYL GDP 7.03125
138 2C78 GNP 7.17949
139 2C77 GNP 7.17949
140 1G6H ADP 7.17949
141 2GKS ADP 7.17949
142 4YJ1 ADP 7.17949
143 1X6V ADP 7.17949
144 5LKC FUC GLA A2G 7.17949
145 1O5Q PYR 7.17949
146 5G3Y ADP 7.17949
147 4PX9 ADP 7.19178
148 1G7C 5GP 7.44681
149 5I0H ADP BEF 7.69231
150 2FNA ADP 7.69231
151 4BFW ZVW 7.69231
152 6CS8 F9Y 7.69231
153 4RD0 GDP 7.8125
154 1JJ7 ADP 7.8125
155 4PPF FLC 7.8125
156 4E03 ADP 7.8125
157 3P4X ADP 7.8125
158 1D2E GDP 7.8125
159 4DDY DN6 7.8125
160 2ZR9 DTP 7.8125
161 5XKT GNP 7.8125
162 1XP8 AGS 7.8125
163 5GVR LMR 7.8125
164 3KJI ADP 7.8125
165 5AK0 8V1 7.8125
166 2ZFI ADP 7.8125
167 3W6G FLC 7.8125
168 3R7F CP 7.8125
169 1PTR PRB 8
170 4H1V GNP 8.20513
171 4PJ3 ANP 8.20513
172 3K5I AIR 8.20513
173 2QZ4 ADP 8.20513
174 3IIJ ADP 8.33333
175 5W7Q GDP 8.59375
176 5H7K GDP 8.59375
177 3W5J GDP 8.59375
178 5H7J GCP 8.59375
179 5MVR ADP 8.59375
180 1G7S GDP 8.59375
181 1FP6 ADP 8.59375
182 2CE7 ADP 8.59375
183 3T1O GDP 8.59375
184 3ZS9 ADP ALF 8.59375
185 2WOJ ADP ALF 8.59375
186 4QOS ADP 8.59375
187 4X8O AP5 8.59375
188 5H68 AGS 8.59375
189 1L2T ATP 8.59375
190 1UJ2 C5P 8.59375
191 1UJ2 ADP 8.59375
192 1SVM ATP 8.59375
193 2DPY ADP 8.71795
194 4KVA GTP 8.71795
195 3UG4 AHR 8.71795
196 3MB5 SAM 8.71795
197 1GXU 2HP 8.79121
198 2GNK ATP 8.92857
199 6A20 ADP 9.23077
200 2VB6 ADP BEF 9.23077
201 2IS6 ADP 9.23077
202 5Y6N ADP 9.23077
203 4PFO ADP 9.23077
204 2GMP NAG MAN 9.23077
205 1APZ ASP 9.25926
206 3RLF ANP 9.375
207 1OYY AGS 9.375
208 2OZE AGS 9.375
209 5H67 ATP 9.375
210 1P4V GLY 9.375
211 1P72 ADP 9.375
212 5HJQ I3P 9.375
213 5MEX PAP 9.375
214 2WJG GDP 9.57447
215 1W0J ADP 9.74359
216 2CK3 ANP 9.74359
217 3B7G ANP 9.74359
218 1W0J ADP BEF 9.74359
219 2CK3 ADP 9.74359
220 2BIF ANP 9.74359
221 2BIF SIN 9.74359
222 6GR0 F8W 9.77011
223 4XVU ATP 10
224 4XTR ATP 10
225 4XTR ADP 10
226 2X77 GDP 10.0529
227 1BO4 COA 10.119
228 1BH2 GSP 10.1562
229 3LRE ADP 10.1562
230 2ODE ALF GDP 10.1562
231 1SVK ALF GDP 10.1562
232 1Y3A GDP 10.1562
233 6CRK GDP 10.1562
234 2OM2 GDP 10.1562
235 4WOP CTP 10.1562
236 3ZQ6 ADP ALF 10.1562
237 5VGR GDP 10.1562
238 6FAA ADP 10.1562
239 2ZJ5 ADP 10.1562
240 4NU0 AP5 10.1562
241 3CV2 OXL 10.1562
242 2BVN GNP 10.2564
243 3U6B GDP 10.2564
244 3U6K GDP 10.2564
245 4PC3 GDP 10.2564
246 2HCJ GDP 10.2564
247 4G5G GDP 10.2564
248 5JBQ GDP 10.2564
249 1D8T GDP 10.2564
250 1F5N GNP 10.2564
251 1XKV ATP 10.2564
252 1AQU A3P 10.2564
253 1NRJ GTP 10.5505
254 2WBV SIA 10.582
255 4JX1 CAM 10.6195
256 4LPS GDP 10.7692
257 1JJV ATP 10.7692
258 5Z69 AGS 10.7692
259 3BP1 GUN 10.7692
260 2WJH FLC 10.8434
261 2WJH GDP 10.8434
262 2BEK ATP 10.8949
263 6MJ7 ARG 10.9091
264 1KK1 GNP 10.9375
265 5CK5 GDP 10.9375
266 2Y65 ADP 10.9375
267 4U00 ADP 10.9375
268 1G41 ADP 10.9375
269 1VHT BA3 10.9375
270 2Q2Y ADP 10.9375
271 2Q2Y MKR 10.9375
272 1KO8 6PG 10.9375
273 3BFX A3P 10.9375
274 4NE2 SH2 10.9375
275 4NE2 ADP 10.9375
276 4PYA 2X3 10.9375
277 3BOS CDP 11.157
278 3BER AMP 11.245
279 2GK6 ADP 11.2821
280 4TL6 ANP 11.2821
281 1NU4 MLA 11.3402
282 5BN3 ADP 11.7188
283 4IHQ ADP 11.7188
284 3EWA ANP 11.7188
285 5L4R CPT 11.7188
286 1XMV ADP 11.7188
287 3FWY ADP 11.7188
288 1ZY5 ANP 11.7188
289 3H4S ADP 11.7188
290 3FYH ADP 11.7188
291 4FRZ ADP 11.7188
292 3PCR GTP 11.7284
293 1TQ4 GDP 11.7949
294 4ZG4 VO4 ADP 11.7949
295 4TTQ ATP 11.7949
296 2QN6 GDP 11.828
297 1OFH ADP 12.069
298 4QM7 GTP 12.2807
299 2XTZ GSP 12.3077
300 1RRC ADP 12.3077
301 1T8U UAP SGN IDS SGN 12.3077
302 1R18 SAH 12.3077
303 2F5X ASP 12.3077
304 1GOJ ADP 12.5
305 4ZKD GDP 12.5
306 1V8K ANP 12.5
307 5XDR ADP 12.5
308 1ZUI SKM 12.5
309 4ZDJ UTP 12.5
310 2OFW ADX 12.5
311 2PEZ DAT 12.5
312 2PEZ GGZ 12.5
313 1WY7 SAH 12.5
314 4DCT GDP 12.8205
315 5IRR GSP 12.8205
316 1LVK MNT BEF 12.8205
317 3KTA AP5 13.1868
318 3T12 GDP ALF 13.2353
319 5UIV ADP 13.2812
320 4ZNL BEF ADP 13.2812
321 1G3Q ADP 13.2812
322 2ZPA ADP 13.2812
323 1NY5 ADP 13.2812
324 1AKY AP5 13.2812
325 5EXT ADP 13.2812
326 1FNZ A2G 13.2812
327 1ION ADP 13.2812
328 3BFV ADP 13.2841
329 1Z6T ADP 13.3333
330 5KDO GDP 13.5135
331 2V7Q ATP 13.6364
332 2V7Q ADP 13.6364
333 4LYA ATP 13.8462
334 2HF9 GSP 13.8462
335 1CR1 TTP 13.8462
336 1JG3 ADN 13.8462
337 1VKJ A3P 14.0625
338 5X20 AOT 14.0625
339 1FQJ ALF 14.2857
340 1FQJ GDP 14.2857
341 5YT0 GDP 14.359
342 2FAH GDP 14.359
343 1E2K TMC 14.359
344 1WDT GTP 14.8438
345 5K5Z ANP 14.8438
346 4A34 FUL 14.8438
347 5FG3 GDP 14.8718
348 1H65 GDP 14.8718
349 4FCW ADP 14.8718
350 4LJ9 ACP 14.8718
351 5N69 ADP 14.8718
352 1P9B GDP 14.8718
353 1B0U ATP 14.8855
354 1YRB GDP 15.3846
355 1SKQ GDP 15.3846
356 1PUJ GNP 15.3846
357 2RCN GDP 15.3846
358 4B47 GDP 15.3846
359 1FNN ADP 15.3846
360 6C90 ADP 15.3846
361 2FSH ANP 15.3846
362 4RZ3 ADP 15.3846
363 1CS4 GSP 15.625
364 3E70 GDP 15.625
365 4HI0 GDP 15.625
366 5L3R GCP 15.625
367 1QF5 RPL 15.625
368 1QF5 GDP 15.625
369 1K6M AGS 15.625
370 4WEI GLC GAL 15.625
371 6AIC AMP 15.625
372 5X40 ACP 15.625
373 5HR5 ADP 15.625
374 3DEF GDP 15.8974
375 1ZD9 GDP 15.9574
376 1JI0 ATP 16.4062
377 1OXV ANP 16.4062
378 1SQ5 ADP 16.4062
379 3TK1 GDP 16.4062
380 4P4T GDP 16.4062
381 1ZIN AP5 16.4062
382 3CX8 GSP 16.4103
383 3AB3 GDP 16.4103
384 3ZIA ADP 16.4103
385 1ZCB GDP 16.4103
386 3ZIA ATP 16.4103
387 5M04 GDP 16.4103
388 5E5U MLT 16.4103
389 4R2I ANP 16.4103
390 4Q1A UDP 16.4103
391 4Q1A 2XZ 16.4103
392 5E5U MLI 16.4103
393 1S3G AP5 16.4103
394 3QKT ANP 16.9231
395 4P3Y GDP 17.033
396 3NHB ADP 17.1875
397 5L3S GNP 17.1875
398 5L3W GDP 17.1875
399 5L3S G 17.1875
400 3PQC GDP 17.4359
401 2CHG ANP 17.4359
402 2J5V PCA 17.4359
403 4MKG AP5 17.4359
404 1Q19 SSC 17.4359
405 3AQ4 GDP 17.9348
406 1MKY GDP 17.9487
407 4WZA ADP 17.9487
408 4WZA ACP 17.9487
409 4YS0 ADP 17.9487
410 4CVN ADP 17.9688
411 5J1J ANP 17.9688
412 1MR3 G3D 18.232
413 4M9Q GNP 18.4615
414 3WY9 GDP 18.75
415 3DOE GTP 18.75
416 3WYA GDP 18.75
417 1W5T ANP 18.75
418 1W5T ADP 18.75
419 5G41 AP5 18.75
420 5W76 GDP 18.9744
421 4BAS GNP 19.4872
422 5LTJ ADP 19.5312
423 5LTJ BEF 19.5312
424 2X7I CIT 19.5312
425 3RC3 ANP 19.5312
426 2NCD ADP 19.5312
427 5DI3 GNP 20
428 2VVG ADP 20
429 3QF7 ANP 20
430 5TSH ADP 20.3125
431 5TSH ANP 20.3125
432 3Q9L ATP 20.3125
433 2XAU ADP 20.3125
434 3IUY AMP 20.3125
435 3FB4 AP5 20.3125
436 1DNP MHF 20.3125
437 3B9Q MLI 21.0938
438 1LOB MMA 21.1538
439 1Y63 ADP 21.1957
440 1ZJ6 G3D 21.5385
441 2QQ0 TMP 21.7391
442 2QQ0 ADP 21.7391
443 2QQ0 ANP 21.7391
444 1F2U ATP 22.2973
445 3WXM GTP 22.6562
446 3VMF GTP 22.6562
447 1KSH GDP 23.6559
448 5KSZ GCP 24.1026
449 2PL3 ADP 24.2188
450 1TE2 PGA 24.2188
451 5KSP GDP 24.7368
452 5KUT GDP 24.8677
453 4A4Z ANP 25
454 2O0J ADP 25
455 3H86 AP5 25
456 1RE0 GDP 26.2195
457 1S9D GDP 26.2195
458 2Z5F A3P 26.5625
459 1UPT GTP 26.6667
460 2J59 GTP 27.1084
461 1J2J GTP 27.1084
462 1O3Y GTP 27.1084
463 4NCN GTP 27.1795
464 4TMZ GSP 27.1795
465 2C9O ADP 27.6923
466 4YLG GDP 27.7457
467 1LVG ADP 28.125
468 3TBK ANP 28.125
469 4V0K GDP 28.9941
470 3Q72 GNP 29.5181
471 2F9L GDP 31.7949
472 5W75 GDP 32.0312
473 1M2O GNP 32.1053
474 1R4A GNP 33.3333
475 2OG2 MLI 33.5938
476 3GJ4 GDP 33.8462
477 3GJ7 GDP 33.8462
478 3GJ5 GDP 33.8462
479 1F6B GDP 33.8462
480 3GJ8 GDP 33.8462
481 3E5H GNP 34.2697
482 5DIF GNP 34.359
483 5UWI GNP 34.359
484 5UWP GNP 34.359
485 5DHF GNP 34.359
486 5UWQ GNP 34.359
487 5UWO GNP 34.359
488 5UWW GNP 34.359
489 5UWT GNP 34.359
490 6CIT GNP 34.359
491 4HAT GNP 34.359
492 5UWS GNP 34.359
493 5UWR GNP 34.359
494 5UWH GNP 34.359
495 5UWJ GNP 34.359
496 5DI9 GNP 34.359
497 1VG8 GNP 34.359
498 1VG0 GDP 34.359
499 3CH5 GDP 34.359
500 3GJ3 GDP 34.359
501 4LX0 BEF GDP 34.4633
502 4ZI2 GNP 34.7368
503 2A5F GTP 34.8571
504 3GJX GTP 34.8718
505 4GOJ GNP 34.9206
506 4C4P GNP 35.2601
507 3M1I GTP 35.3846
508 3WYF GTP 35.3846
509 1YZG GDP 35.7542
510 4KAX GTP 36.0947
511 1VG1 GDP 36.2162
512 1VG9 GDP 36.2162
513 2W83 GTP 36.3636
514 3N5C GDP 36.4198
515 1FZQ GDP 36.4641
516 1Z06 GNP 36.5079
517 2QTV GNP 36.5269
518 5OEC GDP 36.612
519 5JCZ GDP 36.8715
520 3WYG GTP 37.9121
521 2ZEJ GDP 38.0435
522 1WA5 GTP 38.0682
523 5Z2M GTP 38.6364
524 1KAO GDP 39.521
525 2CJW GDP 39.5833
526 2A5J GDP 39.7906
527 1Z2A GDP 39.881
528 5UWU GNP 40
529 3BC1 GNP 40
530 1OIV GDP 40.3141
531 3CPJ GDP 40.5128
532 1OIX GDP 40.8377
533 6AU6 GDP 41.4062
534 3TKL GTP 41.5385
535 2HT6 GDP 42.5287
536 5SZH GNP 42.5641
537 2EW1 GNP 42.5641
538 2A9K GDP 42.7808
539 1Z0A GDP 43.1034
540 3Q85 GNP 43.1953
541 2BME GNP 43.5484
542 5UQW GDP 43.9153
543 3MJH GTP 44.0476
544 1Z0K GTP 44.186
545 3SFV GDP 44.1989
546 1X1R GDP 44.382
547 5OCG GNP 44.4444
548 2BCG GDP 44.6154
549 5TB5 GDP 45.4054
550 5TAR GDP 45.4054
551 3RWO GDP 45.4054
552 1UAD GNP 45.7143
553 2EFE GNH 45.8564
554 5O74 GDP 46.1111
555 4DKX GDP 46.1538
556 1ZC3 GNP 46.2857
557 3T5G GDP 46.4088
558 1D5C GDP 46.9136
559 1Z0F GDP 46.9274
560 4KVG GTP 47.0238
561 1YZN GNP 47.027
562 4HDO GNP 47.3054
563 1GUA GNP 47.3054
564 3X1Z GNP 47.3054
565 4HDQ GNP 47.3054
566 1YVD GNP 47.3373
567 2C5L GTP 47.3988
568 3NKV GNP 47.4286
569 1Z0J GTP 47.6471
570 1EK0 GNP 47.6471
571 1G16 GDP 47.6471
572 6BSX GDP 47.7528
573 6BSX E7S 47.7528
574 5WDR GNP 47.9532
575 2Y8E GNP 48.0447
576 4D0G GTP 48.5714
577 3QBT GNP 48.8506
578 4LHW GNP 48.8506
579 3TNF GNP 48.8506
580 5O2T GSP 49.1124
581 2UZI GTP 49.3976
582 1CLU DBG 49.3976
583 1U8Z GDP 49.4048
584 5E95 GDP 49.4048
585 5LEF GTP 49.7382
586 3DDC GNP 50
587 3KUD GDP 50
Pocket No.: 2; Query (leader) PDB : 1NF3; Ligand: GNP; Similar sites found with APoc: 40
This union binding pocket(no: 2) in the query (biounit: 1nf3.bio3) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2CB8 MYA None
2 2YMZ LAT 3.07692
3 1LOJ URI 3.44828
4 2O66 FLC 3.90625
5 5BSH PRO 4.10256
6 3GU3 SAH 4.10256
7 3F4F UMP 4.19162
8 1USR SIA 4.61538
9 4GOX A3P 4.61538
10 2NSJ C2R 4.6875
11 4PVR ASP 5.64103
12 1UH4 GLC GLC GLC GLC GLC GLC 6.25
13 2UXR ICT 6.25
14 5A1S FLC 6.25
15 1I9G SAM 7.03125
16 5ABU GTG 7.14286
17 1W0H AMP 7.17949
18 3KIF GDL 7.54717
19 1JPA ANP 7.8125
20 3F81 STT 7.8125
21 2XZ9 PYR 8.20513
22 1OSS BEN 8.20513
23 1NHX FTB 8.59375
24 1NHX PEP 8.59375
25 4UBS DIF 10.1562
26 6GSG RCO 10.1562
27 5XQL C2E 10.2564
28 1MLY ACZ PLP 11.2821
29 3TY3 GGG 11.7188
30 1TUK PGM 11.9403
31 1V6A TRE 12.5
32 2H88 TEO 12.5
33 5DG2 GAL GLC 12.5926
34 4O48 ASP 13.2812
35 3AB4 THR 14.0449
36 5NLD LBT 14.0625
37 6H5E ANP 14.0625
38 4G86 BNT 15.3846
39 4E3Q PMP 16.4062
40 3A06 FOM 28.125
Pocket No.: 3; Query (leader) PDB : 1NF3; Ligand: GNP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1nf3.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1NF3; Ligand: GNP; Similar sites found with APoc: 8
This union binding pocket(no: 4) in the query (biounit: 1nf3.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 5ZB0 TYD 4.10256
2 5ZB0 ADP 4.10256
3 5NM7 GLY 5.12821
4 6FMC DUE 7.8125
5 2UVO NDG 8.77193
6 1DL5 SAH 9.375
7 2YOH WMJ 14.359
8 5G6U TRP 16.4062
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