Receptor
PDB id Resolution Class Description Source Keywords
1N6B 2.3 Å EC: 1.14.14.1 MICROSOMAL CYTOCHROME P450 2C5/3LVDH COMPLEX WITH A DIMETHYL DERIVATIVE OF SULFAPHENAZOLE ORYCTOLAGUS CUNICULUS MEMBRANE PROTEIN PROGESTERONE 21-HYDROXYLASE BENZO(A) PYRHYDROXYLASE ESTRADIOL 2-HYDROXYLASE P450 CYP2C5 DIMETHYLSULFAPHENAZOLE COMPLEX OXIDOREDUCTASE
Ref.: STRUCTURE OF A SUBSTRATE COMPLEX OF MAMMALIAN CYTOC P450 2C5 AT 2.3 A RESOLUTION: EVIDENCE FOR MULTIPLE SUBSTRATE BINDING MODES BIOCHEMISTRY V. 42 6370 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DMZ A:501;
Valid;
none;
Kd = 20 uM
327.401 C17 H17 N3 O2 S Cc1cc...
HEM A:500;
Part of Protein;
none;
submit data
616.487 C34 H32 Fe N4 O4 Cc1c2...
SO4 A:502;
A:503;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1N6B 2.3 Å EC: 1.14.14.1 MICROSOMAL CYTOCHROME P450 2C5/3LVDH COMPLEX WITH A DIMETHYL DERIVATIVE OF SULFAPHENAZOLE ORYCTOLAGUS CUNICULUS MEMBRANE PROTEIN PROGESTERONE 21-HYDROXYLASE BENZO(A) PYRHYDROXYLASE ESTRADIOL 2-HYDROXYLASE P450 CYP2C5 DIMETHYLSULFAPHENAZOLE COMPLEX OXIDOREDUCTASE
Ref.: STRUCTURE OF A SUBSTRATE COMPLEX OF MAMMALIAN CYTOC P450 2C5 AT 2.3 A RESOLUTION: EVIDENCE FOR MULTIPLE SUBSTRATE BINDING MODES BIOCHEMISTRY V. 42 6370 2003
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 1NR6 Kd ~ 50 uM DIF C14 H11 Cl2 N O2 c1ccc(c(c1....
2 1N6B Kd = 20 uM DMZ C17 H17 N3 O2 S Cc1ccc(cc1....
70% Homology Family (39)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3T3R Ki = 101 uM 9PL C11 H16 N2 O2 CC[C@H]1[C....
2 2FDY - D4G C10 H8 N2 S2 c1cnccc1SS....
3 2FDV Ki = 800 nM D2G C11 H12 N2 O CNCc1ccc(o....
4 4EJH Kd = 4.4 uM 0QA C10 H13 N3 O2 CN(CCCC(=O....
5 3EBS Kd = 21 uM N4E C10 H13 N O2 CCOc1ccc(c....
6 1Z10 Kd = 0.27 uM COU C9 H6 O2 c1ccc2c(c1....
7 4EJI Kd = 4.4 uM 0QA C10 H13 N3 O2 CN(CCCC(=O....
8 2FDU Ki = 14200 nM D1G C12 H14 N2 O CN(C)Cc1cc....
9 2FDW Ki = 130 nM D3G C10 H10 N2 O c1cc(cnc1)....
10 2P85 - IND C8 H7 N c1ccc2c(c1....
11 1Z11 Kd = 1.9 uM 8MO C12 H8 O4 COc1c2c(cc....
12 4EJJ Kd = 470 uM NCT C10 H14 N2 C[N@@]1CCC....
13 4EJG - NCT C10 H14 N2 C[N@@]1CCC....
14 3T3Q Ki = 49 uM 9PL C11 H16 N2 O2 CC[C@H]1[C....
15 5E58 Kd = 2.3 uM CPZ C9 H7 Cl N2 c1cc(ccc1c....
16 1NR6 Kd ~ 50 uM DIF C14 H11 Cl2 N O2 c1ccc(c(c1....
17 1N6B Kd = 20 uM DMZ C17 H17 N3 O2 S Cc1ccc(cc1....
18 4RRT Kd = 1.82 uM 3V4 C10 H16 CC1=CC[C@H....
19 4ZV8 - TMH C10 H16 CC1=CC[C@@....
20 5UEC - 85D C10 H15 Br CC1([C@@H]....
21 3IBD - CPZ C9 H7 Cl N2 c1cc(ccc1c....
22 5UAP - 82S C10 H17 Br C[C@@]12CC....
23 4RQL Kd = 0.08 uM SNE C10 H16 CC(C)[C@@]....
24 4I91 Kd = 0.22 uM TMH C10 H16 CC1=CC[C@@....
25 5UFG - 85D C10 H15 Br CC1([C@@H]....
26 3QOA Kd = 0.21 uM 3QO C12 H11 N c1ccc(cc1)....
27 5UDA - CAE C10 H18 CC1(C2CCC1....
28 2NNJ Ki = 90 nM 225 C18 H19 Cl2 N O4 CCOC(=O)C1....
29 3G5N ic50 = 0.035 uM PB2 C16 H14 N2 c1ccc(cc1)....
30 3TMZ ic50 = 2 uM 06X C20 H25 Cl N2 O5 CCOC(=O)C1....
31 2BDM ic50 = 0.9 uM TMI C22 H18 N2 c1ccc(cc1)....
32 4JLT Kd = 0.7 uM 8PR C19 H20 F N O3 c1cc(ccc1[....
33 4MGJ - CPZ C9 H7 Cl N2 c1cc(ccc1c....
34 1SUO ic50 = 0.04 uM CPZ C9 H7 Cl N2 c1cc(ccc1c....
35 5W0C - 9W6 C15 H12 N4 O4 S2 CCOC(=O)NC....
36 4NZ2 Kd = 2 uM 2QJ C16 H12 Br Cl F3 N O4 S C[C@@](C(=....
37 1R9O - FLP C15 H13 F O2 C[C@@H](c1....
38 5K7K ic50 = 36 nM 6RJ C19 H12 Cl N5 O3 S2 c1cc(c(cc1....
39 3T3Z Ki = 765 uM 9PL C11 H16 N2 O2 CC[C@H]1[C....
50% Homology Family (43)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3T3R Ki = 101 uM 9PL C11 H16 N2 O2 CC[C@H]1[C....
2 2FDY - D4G C10 H8 N2 S2 c1cnccc1SS....
3 2FDV Ki = 800 nM D2G C11 H12 N2 O CNCc1ccc(o....
4 4EJH Kd = 4.4 uM 0QA C10 H13 N3 O2 CN(CCCC(=O....
5 3EBS Kd = 21 uM N4E C10 H13 N O2 CCOc1ccc(c....
6 1Z10 Kd = 0.27 uM COU C9 H6 O2 c1ccc2c(c1....
7 4EJI Kd = 4.4 uM 0QA C10 H13 N3 O2 CN(CCCC(=O....
8 2FDU Ki = 14200 nM D1G C12 H14 N2 O CN(C)Cc1cc....
9 2FDW Ki = 130 nM D3G C10 H10 N2 O c1cc(cnc1)....
10 2P85 - IND C8 H7 N c1ccc2c(c1....
11 1Z11 Kd = 1.9 uM 8MO C12 H8 O4 COc1c2c(cc....
12 4EJJ Kd = 470 uM NCT C10 H14 N2 C[N@@]1CCC....
13 4EJG - NCT C10 H14 N2 C[N@@]1CCC....
14 3T3Q Ki = 49 uM 9PL C11 H16 N2 O2 CC[C@H]1[C....
15 5E58 Kd = 2.3 uM CPZ C9 H7 Cl N2 c1cc(ccc1c....
16 1NR6 Kd ~ 50 uM DIF C14 H11 Cl2 N O2 c1ccc(c(c1....
17 1N6B Kd = 20 uM DMZ C17 H17 N3 O2 S Cc1ccc(cc1....
18 4RRT Kd = 1.82 uM 3V4 C10 H16 CC1=CC[C@H....
19 4ZV8 - TMH C10 H16 CC1=CC[C@@....
20 5UEC - 85D C10 H15 Br CC1([C@@H]....
21 3IBD - CPZ C9 H7 Cl N2 c1cc(ccc1c....
22 5UAP - 82S C10 H17 Br C[C@@]12CC....
23 4RQL Kd = 0.08 uM SNE C10 H16 CC(C)[C@@]....
24 4I91 Kd = 0.22 uM TMH C10 H16 CC1=CC[C@@....
25 5UFG - 85D C10 H15 Br CC1([C@@H]....
26 3QOA Kd = 0.21 uM 3QO C12 H11 N c1ccc(cc1)....
27 5UDA - CAE C10 H18 CC1(C2CCC1....
28 2NNJ Ki = 90 nM 225 C18 H19 Cl2 N O4 CCOC(=O)C1....
29 4XRZ ic50 = 0.37 uM SI6 C16 H16 F2 N4 O S c1cc(c(cc1....
30 4WNU - QDN C20 H24 N2 O2 COc1ccc2c(....
31 4WNV - QI9 C20 H24 N2 O2 COc1ccc2c(....
32 4XRY ic50 = 13.9 uM SI5 C17 H18 F2 N4 O S Cn1cc(cn1)....
33 3G5N ic50 = 0.035 uM PB2 C16 H14 N2 c1ccc(cc1)....
34 3TMZ ic50 = 2 uM 06X C20 H25 Cl N2 O5 CCOC(=O)C1....
35 2BDM ic50 = 0.9 uM TMI C22 H18 N2 c1ccc(cc1)....
36 4JLT Kd = 0.7 uM 8PR C19 H20 F N O3 c1cc(ccc1[....
37 4MGJ - CPZ C9 H7 Cl N2 c1cc(ccc1c....
38 1SUO ic50 = 0.04 uM CPZ C9 H7 Cl N2 c1cc(ccc1c....
39 5W0C - 9W6 C15 H12 N4 O4 S2 CCOC(=O)NC....
40 4NZ2 Kd = 2 uM 2QJ C16 H12 Br Cl F3 N O4 S C[C@@](C(=....
41 1R9O - FLP C15 H13 F O2 C[C@@H](c1....
42 5K7K ic50 = 36 nM 6RJ C19 H12 Cl N5 O3 S2 c1cc(c(cc1....
43 3T3Z Ki = 765 uM 9PL C11 H16 N2 O2 CC[C@H]1[C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DMZ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 DMZ 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1N6B; Ligand: DMZ; Similar sites found: 39
This union binding pocket(no: 1) in the query (biounit: 1n6b.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4WG0 CHD 0.01013 0.41659 None
2 1UO5 PIH 0.009397 0.40898 None
3 2VWA PTY 0.03269 0.40282 None
4 3KP6 SAL 0.01416 0.41539 1.3245
5 3FS1 ALA ALA LEU ALA ALA LEU LEU ALA ALA 0.009448 0.42309 2.17391
6 3LE7 ADE 0.01151 0.41629 2.29885
7 3HP9 CF1 0.02351 0.40074 2.32558
8 5U8U FAD 0.04843 0.40781 2.537
9 2Q0D ATP 0.01616 0.40563 2.54958
10 3B1M KRC 0.006023 0.41384 2.82686
11 4HEE 14R 0.008702 0.40481 2.83688
12 1FM9 570 0.01724 0.4043 2.94118
13 3KDU NKS 0.01397 0.4246 3.2491
14 3FEI CTM 0.01185 0.40369 3.37079
15 1IQ7 NAG 0.001272 0.4422 3.47826
16 5G3N X28 0.007612 0.40921 3.93701
17 5ECP ATP 0.03184 0.40085 4.03587
18 1NQ7 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 0.01692 0.40108 4.5082
19 5AAV GW5 0.04039 0.40578 4.7619
20 2OCI TYC 0.01937 0.40342 5.90551
21 1YOK P6L 0.01406 0.41423 6.25
22 3SJH LAR 0.01923 0.40081 6.93333
23 4V2O CLQ 0.00885 0.41492 8.53659
24 2WH8 II2 0.01061 0.40266 8.71671
25 1YP1 LYS ASN LEU 0.01806 0.40401 8.91089
26 4MA6 28E 0.00865 0.42015 10.1911
27 1L0I PSR 0.01873 0.41168 12.8205
28 5V4R MGT 0.02079 0.40535 12.963
29 3NGU ADP 0.02343 0.40126 13.245
30 3O01 DXC 0.004495 0.42897 14.9351
31 5IBE 69M 0.008645 0.42551 16.6667
32 4B7S QLE 0.0001381 0.44191 17.4312
33 5L92 C0R 0.002997 0.43885 19.7561
34 4J6C STR 0.00494 0.42733 20.7317
35 2V57 PRL 0.007505 0.42788 21.0526
36 1ZOY UQ1 0.01731 0.40909 21.4286
37 3A51 VDY 0.002857 0.42048 25.0608
38 4UBS DIF 0.01406 0.41666 31.2977
39 3MDV CL6 0.006671 0.41204 41.886
Pocket No.: 2; Query (leader) PDB : 1N6B; Ligand: DMZ; Similar sites found: 346
This union binding pocket(no: 2) in the query (biounit: 1n6b.bio2) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2O66 FLC 0.0048 0.44423 None
2 3F8C HT1 0.008847 0.43192 None
3 3KPE TM3 0.02826 0.41314 None
4 3CKZ ZMR 0.00007276 0.4165 1.03896
5 4LCQ URQ 0.000004323 0.42414 1.05708
6 4PB2 5UD 0.0003771 0.44963 1.17925
7 1Z44 NPO 0.003583 0.49733 1.18343
8 1Z41 FMN 0.008014 0.40753 1.18343
9 1Z44 FMN 0.01129 0.40532 1.18343
10 3CXO 1N5 0.00002925 0.41238 1.20482
11 3GTD MLI 0.03592 0.40353 1.2685
12 1P4C FMN 0.0001084 0.43328 1.31579
13 1KYZ SAH 0.004095 0.41137 1.36986
14 3MD0 GDP 0.01964 0.40695 1.40845
15 3TI8 LNV 0.0000005888 0.45598 1.51899
16 2Q37 3AL 0.004357 0.44617 1.65746
17 1V5F FAD 0.000242 0.45544 1.69133
18 1V5F TPP 0.000242 0.45544 1.69133
19 4PNI KQQ 0.001877 0.40644 1.69133
20 4B7J G39 0.00004488 0.40859 1.70576
21 4P87 4NP 0.00001673 0.46465 1.74564
22 3K3G MMU 0.000009623 0.56413 1.76471
23 1EYE PMM 0.01433 0.40486 1.78571
24 1PX8 XYP 0.01456 0.42187 1.8
25 2QLX RM4 0.02682 0.41939 1.85185
26 2J5S KTA 0.00137 0.42895 1.90114
27 3A1I UNU 0.00466 0.42944 1.90275
28 3O2K QRP 0.006664 0.42287 1.90275
29 2BJK NAD 0.000134 0.42076 1.90275
30 2VAR AMP 0.003577 0.43429 1.91693
31 2VAR KDF 0.003244 0.43141 1.91693
32 2NZ2 ASP 0.000232 0.49768 1.93705
33 2NZ2 CIR 0.00002135 0.46134 1.93705
34 2X61 CH 0.00003633 0.42175 1.93798
35 2X61 NGA GAL SIA 0.0005625 0.40674 1.93798
36 4A8H PUW 0.00008888 0.42927 1.97183
37 1HV9 UD1 0.00006659 0.42781 1.97368
38 4B9E FAH 0.01406 0.43339 1.99336
39 1OMZ UD2 0.00004557 0.42424 2.04778
40 4QN7 G39 0.000003065 0.44173 2.05128
41 4A3R CIT 0.00002299 0.42006 2.09302
42 4AF0 IMP 0.000001669 0.4673 2.11416
43 2ZJ5 ADP 0.01926 0.41621 2.11416
44 3PC3 P1T 0.003219 0.40821 2.11416
45 1JH7 UVC 0.02701 0.40934 2.1164
46 2NLI LAC 0.000003506 0.46107 2.17391
47 2NLI FMN 0.000003506 0.46107 2.17391
48 3DG6 MUC 0.009139 0.40901 2.17984
49 4KCF FMN 0.000001812 0.45215 2.20264
50 4KCF AKM 0.000008601 0.45054 2.20264
51 4M5P MLA 0.0009632 0.51888 2.2113
52 4M5P 23W 0.003756 0.46907 2.2113
53 4N02 FNR 0.00003476 0.43625 2.2409
54 3FSJ D7K 0.00001665 0.45812 2.32558
55 2YIV NBN 0.01425 0.43311 2.32558
56 3Q9T FAY 0.0001009 0.40905 2.32558
57 3HAZ FAD 0.0005032 0.40592 2.32558
58 1Z4V DAN 0.0004197 0.40247 2.32558
59 1QD0 RR6 0.008169 0.41492 2.34375
60 1QCA FUA 0.0001125 0.43202 2.34742
61 1TFZ 869 0.005928 0.40207 2.35849
62 2H6B 3C4 0.00001846 0.44581 2.4
63 4KOA NDP 0.006737 0.40683 2.4024
64 1F8F NAD 0.0002071 0.41697 2.42588
65 2BJF DXC 0.000007754 0.42273 2.43161
66 1I2B USQ 0.00009218 0.46193 2.47525
67 1I2B NAD 0.00009218 0.46193 2.47525
68 1I2B UPG 0.00009218 0.46193 2.47525
69 1E5F PLP 0.007448 0.40877 2.47525
70 3GJB AKG 0.01458 0.41262 2.50784
71 2IMP NAI 0.0003588 0.42539 2.537
72 1UOU CMU 0.008826 0.40961 2.537
73 3VOZ 04A 0.0001584 0.46854 2.53968
74 4OYA 1VE 0.0004213 0.43258 2.55319
75 1A8S PPI 0.0004421 0.46972 2.5641
76 4QDC ASD 0.00009481 0.43915 2.5641
77 3I8P 840 0.008607 0.40632 2.57611
78 3UXL CFI 0.000004351 0.42773 2.61097
79 3DGB MUC 0.008146 0.41497 2.6178
80 1E4E ADP 0.00237 0.42015 2.62391
81 1V8K ANP 0.00008048 0.42882 2.68293
82 2Q1W NAD 0.0006039 0.40084 2.7027
83 3CQ5 PMP 0.02261 0.40427 2.71003
84 1FWY UD1 0.00001564 0.44554 2.71903
85 1CKM GTP 0.002828 0.44365 2.72727
86 3F81 STT 0.04765 0.41774 2.73224
87 1KW6 BPY 0.0001065 0.43024 2.73973
88 3MB5 SAM 0.000004893 0.45716 2.7451
89 1YBH FAD 0.000003373 0.48935 2.74841
90 1VCO GLN 0.00004626 0.45081 2.74841
91 1YBH P22 0.00003182 0.41044 2.74841
92 4FUA PGH 0.0002554 0.42755 2.7907
93 4KS1 2H8 0.000146 0.41095 2.82051
94 1A59 CIT 0.02713 0.41914 2.91005
95 1A59 COA 0.006579 0.40375 2.91005
96 3VCA PRO 0.000324 0.4947 2.91262
97 2WL9 MBD 0.00002201 0.46975 2.95082
98 2YYJ FAD 0.00006263 0.44897 2.95983
99 2YYJ 4HP 0.00006263 0.44897 2.95983
100 1KTC NGA 0.0314 0.40198 2.96296
101 1MVQ MMA 0.0005179 0.40556 2.9661
102 3KMZ EQO 0.001859 0.40051 3.00752
103 1NU4 MLA 0.001747 0.45275 3.09278
104 1F1V DHY 0.01203 0.41627 3.09598
105 3TFC PEP 0.0106 0.42331 3.11688
106 1MXI SAH 0.006239 0.40461 3.125
107 1TV5 ORO 0.0001749 0.46949 3.16027
108 1TV5 N8E 0.0009279 0.43519 3.16027
109 1TV5 A26 0.001528 0.41605 3.16027
110 1TV5 FMN 0.00004615 0.40529 3.16027
111 1QJC PNS 0.00002782 0.4394 3.16456
112 2YP9 SIA CMO 0.0004505 0.45373 3.17125
113 3BRE C2E 0.009949 0.43497 3.17125
114 1WDA BAG 0.006816 0.42703 3.17125
115 4DN8 BMA 0.002399 0.46454 3.20513
116 1QZZ SAM 0.005424 0.41808 3.20856
117 4HE2 AMP 0.00003099 0.44075 3.25444
118 4G1V FAD 0.00008198 0.45246 3.25815
119 2PP3 LGT 0.01475 0.40067 3.26633
120 4KQL 1SG 0.00006862 0.43559 3.28947
121 4MOB ADP 0.001385 0.43502 3.31325
122 2ZJF BSU 0.007216 0.42141 3.31492
123 2NCD ADP 0.02438 0.41143 3.33333
124 3Q3C NAD 0.0001193 0.42166 3.34448
125 3FPZ AHZ 0.0001194 0.43938 3.37423
126 2GGH NLQ 0.00006243 0.419 3.38266
127 4CMF PXG 0.000003252 0.46195 3.41615
128 3UEC ALA ARG TPO LYS 0.01004 0.44066 3.42466
129 2F2U M77 0.005753 0.42557 3.48259
130 4M37 SAH 0.006653 0.40026 3.49854
131 1RZM E4P 0.03035 0.4167 3.5503
132 1SQ5 PAU 0.01949 0.41137 3.57143
133 1SQ5 ADP 0.01237 0.40749 3.57143
134 1QDS PGA 0.002444 0.44128 3.58566
135 2Z5Y HRM 0.00001378 0.45881 3.59408
136 1VQ2 DDN 0.0004827 0.41181 3.62694
137 1Y9Q MED 0.04888 0.40156 3.64583
138 1N9L FMN 0.0002165 0.45853 3.66972
139 2Y7P SAL 0.007439 0.43021 3.66972
140 3SHR CMP 0.02046 0.4022 3.67893
141 1K6M AGS 0.001399 0.41736 3.7037
142 3P7I P7I 0.00387 0.44295 3.73832
143 3R51 MMA 0.0032 0.48078 3.75
144 1UGX GAL MGC 0.0001145 0.43121 3.7594
145 3RK0 AMP 0.01607 0.4028 3.79747
146 3NKT 1HN 0.0003437 0.4235 3.80435
147 1Q3Q ANP 0.000008332 0.45737 3.8055
148 4WVH ASP HIS ASP ALA HIS ALA 0.009951 0.41986 3.8055
149 1TIW TFB 0.0002055 0.40114 3.8055
150 1TIW FAD 0.0002055 0.40114 3.8055
151 1EB9 HBA 0.002149 0.43875 3.81679
152 4C6F NCD 0.01862 0.40394 3.81679
153 4C6F DOR 0.01862 0.40394 3.81679
154 2F59 INI 0.004178 0.41105 3.82166
155 1Y1A GSH 0.002734 0.51078 3.82514
156 1DXY COI 0.001763 0.40423 3.9039
157 1XIU REA 0.001027 0.4378 3.91304
158 1NHZ 486 0.003148 0.40526 3.92857
159 2YLD CMO 0.006174 0.4449 3.93701
160 1BDB NAD 0.000001297 0.49168 3.97112
161 4E28 9MZ 0.04535 0.40315 4
162 2RL1 UD1 0.001067 0.41122 4.00943
163 1ZFJ IMP 0.0004491 0.43068 4.01691
164 4LTN FMN 0.00009974 0.4153 4.06091
165 2P8B NSK 0.0002616 0.44199 4.06504
166 2Q1A 2KT 0.0003044 0.44011 4.09556
167 1EDO NAP 0.000004539 0.47427 4.09836
168 4EXO PYR 0.002139 0.48162 4.10959
169 3IU9 T07 0.0007031 0.40487 4.16667
170 3NOJ PYR 0.0005265 0.48511 4.20168
171 1WRA PC 0.01933 0.4265 4.22078
172 3MAG 3MA 0.04629 0.42485 4.23453
173 3S9K CIT 0.01562 0.45092 4.23729
174 4C2G ALA ALA ALA ALA 0.01659 0.41016 4.26009
175 1FX8 BOG 0.0004725 0.45057 4.27046
176 3K9W ADE 0.0005709 0.42699 4.27807
177 3K9W 4PS 0.0005709 0.42699 4.27807
178 4NAO AKG 0.02097 0.42473 4.29448
179 1F3L SAH 0.0004873 0.4331 4.36137
180 1P1M MET 0.003691 0.40289 4.4335
181 4IVG ANP 0.00001858 0.4415 4.43975
182 1J2Z SOG 0.0009316 0.44162 4.44444
183 3EW2 BTN 0.004547 0.43468 4.44444
184 1ECM TSA 0.005872 0.42985 4.58716
185 1K27 MTM 0.000364 0.40703 4.59364
186 1JQ5 NAD 0.00004494 0.47366 4.59459
187 5T63 ALA ALA ALA ALA 0.0007404 0.42686 4.63215
188 1WVC CTP 0.0003061 0.42993 4.6332
189 1FNZ A2G 0.001215 0.41947 4.64135
190 4RJK PYR 0.01057 0.44595 4.65116
191 3VGL BGC 0.000001838 0.48507 4.6729
192 2HFK E4H 0.01789 0.41306 4.70219
193 1GSA GSH 0.0000009015 0.46611 4.74684
194 1GSA ADP 0.000007248 0.45021 4.74684
195 5DTF 5CT 0.02465 0.43003 4.78261
196 2JFV FLC 0.02992 0.41194 4.811
197 1SJW NGV 0.006062 0.41226 4.86111
198 3NJQ NJQ 0.0002211 0.42951 4.86258
199 4MWV BCZ 0.00001572 0.42827 4.89691
200 3RO7 TDR 0.002775 0.40623 4.90566
201 1YRX FMN 0.0005675 0.45227 4.95868
202 1H16 PYR 0.003805 0.46878 5.074
203 1XVA SAM 0.005971 0.40196 5.13699
204 3RF4 FUN 0.01875 0.41213 5.17241
205 1H8G CHT 0.0016 0.51772 5.26316
206 1G6O ADP 0.00001981 0.44497 5.28541
207 4Q0A 4OA 0.001846 0.42416 5.28541
208 1RM4 NDP 0.00001251 0.45445 5.34125
209 1ONX ASP 0.000009824 0.4719 5.38462
210 1YBQ BDH 0.00001102 0.43896 5.38462
211 3CF6 SP1 0.005687 0.41334 5.49683
212 3PHQ KDO 0.02222 0.45682 5.52995
213 3OYZ ACO 0.0001891 0.40213 5.54273
214 2GN2 C5P 0.0002174 0.46334 5.55556
215 1RP0 AHZ 0.000003017 0.47935 5.6338
216 1YOA FMN 0.04543 0.43263 5.66038
217 2QCX PF1 0.01092 0.42767 5.70342
218 3LTW HLZ 0.007548 0.44072 5.71429
219 1I9G SAM 0.00001692 0.438 5.71429
220 2BLE 5GP 0.000008262 0.45947 5.72207
221 3P3N AKG 0.01338 0.4288 5.73066
222 2BGM NAJ 0.00002441 0.44445 5.7554
223 3BHO B4P 0.04702 0.42447 5.76923
224 3K37 BCZ 0.00007743 0.44348 5.79345
225 4JP3 CIT 0.00008549 0.42154 5.85774
226 1O6B ADP 0.000231 0.4068 5.91716
227 4LKK SIA GAL 0.000067 0.47733 5.95238
228 2Y7G AAE 0.005172 0.41494 6.02837
229 4COQ SAN 0.01142 0.4321 6.07287
230 4GQB 0XU 0.00001322 0.44768 6.10465
231 3EJ0 11X 0.005405 0.43909 6.12245
232 4DYO SD4 0.02298 0.40396 6.13108
233 2DWU DGL 0.0076 0.42497 6.15942
234 1Q11 TYE 0.002799 0.44926 6.1828
235 2OFE NAG 0.03484 0.40873 6.33803
236 2IZ1 ATR 0.01029 0.43427 6.34249
237 2EJU SAH 0.006542 0.40384 6.34921
238 2WK1 SAH 0.001533 0.41955 6.38298
239 1FW1 GSH 0.01312 0.40271 6.48148
240 1B5E DCM 0.0273 0.40066 6.50407
241 4TMK T5A 0.00002416 0.4755 6.57277
242 4F4S EFO 0.01511 0.41637 6.57895
243 1A5Z OXM 0.00002107 0.5845 6.58307
244 1A5Z FBP 0.0004997 0.4408 6.58307
245 2B7N NTM 0.04236 0.40016 6.59341
246 2P2V CSF 0.000006761 0.40062 6.59722
247 2BII MTV 0.00106 0.41797 6.60377
248 1RSD PSB 0.0005995 0.44835 6.61157
249 1NVU GTP 0.0001155 0.42394 6.62651
250 1NVV GNP 0.000001866 0.40314 6.62651
251 2JBH 5GP 0.01025 0.41931 6.66667
252 2QS8 MET 0.0000005465 0.44352 6.69856
253 3KMT SAH 0.007271 0.41298 6.72269
254 1W7J ADP BEF 0.0007797 0.44233 6.76533
255 4LHM AZZ 0.002181 0.46008 6.81818
256 3ZF8 GDP 0.01306 0.41049 6.88525
257 4U9W COA 0.001623 0.42428 6.97674
258 4Q3S X7A 0.0005281 0.41602 7.01299
259 3BY8 MLT 0.001607 0.48008 7.04225
260 1WL4 COA 0.0001135 0.41382 7.0529
261 1ZZ7 S0H 0.005443 0.4363 7.07071
262 4M7F BM3 0.03302 0.40099 7.07965
263 2C1Q BTN 0.000006294 0.44134 7.14286
264 3OIG NAD 0.00009804 0.42952 7.14286
265 3OIG IMJ 0.00001631 0.41988 7.14286
266 4HZX G39 0.0000004838 0.47002 7.2165
267 2C2A ADP 0.008156 0.40368 7.36434
268 1Y0L HAN 0.03248 0.43358 7.40741
269 1T26 NAI 0.0000271 0.46635 7.45342
270 1T26 GBD 0.0000271 0.46635 7.45342
271 2ET1 GLV 0.0000441 0.41369 7.46269
272 3CL7 HYN 0.000004943 0.40903 7.46753
273 1Y7P RIP 0.02142 0.41895 7.62332
274 2ZO9 MLI 0.0006437 0.46294 7.66423
275 3I0O ADP 0.01632 0.40638 7.66962
276 3ZZS TRP 0.0001123 0.40312 7.69231
277 4QCK ASD 0.00001896 0.46733 7.77202
278 1TDF NAP 0.001187 0.40641 7.91139
279 2ZWS PLM 0.01529 0.46052 8.03383
280 1G7V PAI 0.0001526 0.40571 8.09859
281 3MMR ABH 0.00005643 0.45215 8.24524
282 2HMT NAI 0.0000002055 0.49166 8.33333
283 2WMO GTP 0.00259 0.43091 8.42105
284 3HPF GAE 0.00007188 0.41738 8.4399
285 1ULE GLA GAL NAG 0.01339 0.42878 8.66667
286 1WNG SAH 0.002378 0.41639 8.67924
287 1TUV VK3 0.03118 0.42775 8.77193
288 3CH5 GDP 0.00005019 0.42792 8.7963
289 2FR6 CTN 0.001741 0.4251 8.90411
290 2FR6 URI 0.005023 0.40809 8.90411
291 3O03 NAP 0.0002653 0.41577 8.93471
292 1MZV AMP 0.005009 0.42811 8.93617
293 4IAE 1DX 0.00002649 0.4368 8.99471
294 1LTH NAD 0.00002507 0.44011 9.30233
295 4JCA CIT 0.02526 0.43974 9.58084
296 3QV9 QV7 0.03625 0.40335 9.72516
297 1JA9 NDP 0.00003161 0.45015 9.85401
298 1JA9 PYQ 0.00000609 0.42043 9.85401
299 1GXU 2HP 0.001673 0.4147 9.89011
300 2V5E SCR 0.03974 0.42862 9.90099
301 4K30 NLG 0.01945 0.40313 10
302 1Y75 NAG 0.009839 0.42008 10.1695
303 1Y42 TYR 0.009225 0.42601 10.2041
304 1I0Z OXM 0.00101 0.50749 10.2102
305 4N7C AEF 0.03856 0.41147 10.2273
306 4P4T GDP 0.00284 0.41725 10.3594
307 2HVK TBA 0.00004875 0.54533 10.3774
308 1V6A TRE 0.005241 0.44246 10.5708
309 1T0S BML 0.005708 0.45973 10.6061
310 1QO0 BMD 0.01907 0.42138 10.6494
311 1PEA ACM 0.04598 0.41282 10.6494
312 4NTX AMR 0.03545 0.40166 10.9244
313 1ZS6 ADP 0.008829 0.42213 11.2426
314 1LDM NAD 0.000001887 0.48139 11.2462
315 4CCO OGA 0.0164 0.41476 11.5632
316 4G4S LDZ 0.004699 0.41277 11.6
317 2FOI JPA 0.008713 0.41794 11.6667
318 2GJ3 FAD 0.00001831 0.41265 11.6667
319 2YDW WSH 0.008252 0.41894 11.7647
320 5D6C 57S 0.005746 0.47133 11.8182
321 1GJW GLC 0.01982 0.42596 11.8393
322 2Y6P CTP 0.01821 0.40435 11.9658
323 4OB6 S2T 0.003087 0.42367 12.0235
324 3QDT A2G GAL 0.00566 0.45991 12.5874
325 3QDY A2G GAL 0.00614 0.4581 12.5874
326 3QDY CBS 0.0176 0.42853 12.5874
327 4IMG NGF 0.003256 0.41147 12.628
328 1WKL ADP 0.004426 0.41012 13.1387
329 2VDJ HSE 0.01467 0.43861 13.289
330 2E1A MSE 0.003756 0.4383 13.3333
331 1TH8 ADP 0.004128 0.43166 13.7931
332 3KJQ B94 0.01579 0.40312 14.0244
333 1X1T NAD 0.00004428 0.44754 14.2308
334 43CA NPO 0.01701 0.46067 14.5299
335 2PVQ GSH 0.009301 0.40151 14.9254
336 1EXB NDP 0.00004835 0.44644 15.534
337 1G8S MET 0.01247 0.43027 15.6522
338 2FH5 GTP 0.0009181 0.43128 15.8879
339 4EKV BTN 0.00003739 0.4123 16.3522
340 1OFH ADP 0.0009827 0.40083 17.2414
341 3H86 AP5 0.0003055 0.40517 18.75
342 1SS4 CIT 0.0001778 0.57773 18.9542
343 3SIX GDP 0.005678 0.42142 23.0303
344 2XD9 XD9 0.00003332 0.48057 28.1437
345 2FYU FDN 0.00479 0.40885 29.0323
346 1O9U ADZ 0.003976 0.47574 38.8889
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