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Receptor
PDB id Resolution Class Description Source Keywords
1MFI 1.8 Å NON-ENZYME: TOXIN_VIRAL CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE MUS MUSCULUS CYTOKINE MACROPHAGE INFLAMMATORY RESPONSE TAUTOMERASE VIPROTEIN
Ref.: CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE AT 1 RESOLUTION: IMPLICATIONS FOR ENZYMATIC CATALYSIS AN INHIBITION. BIOCHEMISTRY V. 38 7444 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FHC A:115;
B:116;
C:117;
Valid;
Valid;
Valid;
none;
none;
none;
Ki = 2.6 uM
181.141 C9 H6 F O3 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1MFI 1.8 Å NON-ENZYME: TOXIN_VIRAL CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE MUS MUSCULUS CYTOKINE MACROPHAGE INFLAMMATORY RESPONSE TAUTOMERASE VIPROTEIN
Ref.: CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE AT 1 RESOLUTION: IMPLICATIONS FOR ENZYMATIC CATALYSIS AN INHIBITION. BIOCHEMISTRY V. 38 7444 1999
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 62 families.
1 1MFI Ki = 2.6 uM FHC C9 H6 F O3 c1cc(ccc1C....
70% Homology Family (28)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1LJT ic50 = 7 uM HDI C12 H13 N O4 COC(=O)C[C....
2 3L5R ic50 = 38 nM 47X C15 H10 O5 c1cc(c(cc1....
3 5J7Q Ki = 26.6 uM 6H2 C13 H10 N2 O2 c1ccn2cc(n....
4 5HVT Kd = 0.055 uM NVS C15 H13 N O4 COc1ccc(cc....
5 5B4O - 6DQ C13 H8 N2 O S c1ccc2c(c1....
6 1GCZ Ki = 7.4 uM YZ9 C12 H10 O5 CCOC(=O)C1....
7 3L5P - 428 C9 H11 N3 O CC(C)c1cn2....
8 5HVS Kd = 0.071 uM 65V C24 H15 F N4 O4 c1cc(cc(c1....
9 6B1C Ki = 0.075 uM C9J C17 H12 F N5 O2 CN1C=Cc2cc....
10 3L5T - 956 C20 H18 N4 O2 S CN1c2ccccc....
11 3IJJ - EN1 C9 H8 O4 c1cc(ccc1/....
12 6CBG Ki = 113 uM EWG C10 H8 N2 O2 c1cc(cc(c1....
13 4K9G - 1Q1 C12 H12 F N O3 CC(=O)C[C@....
14 3IJG Kd = 54 uM AVR C13 H17 N3 O C[C@H](C(=....
15 4WRB Ki = 0.65 uM 3TW C20 H18 N4 O3 COCCOc1ccc....
16 1CA7 - ENO C9 H8 O4 c1cc(ccc1C....
17 2OOH ic50 = 1.3 uM OX3 C14 H17 N O3 c1cc(ccc1C....
18 2OOZ ic50 = 7 uM OX5 C13 H17 N O3 CC(C)(C)CC....
19 3DJI - 3E1 C16 H16 N2 O4 CC(=O)Nc1c....
20 6CBF Ki = 6.8 uM EWD C16 H12 N2 O3 c1ccc(cc1)....
21 3L5U - ZEC C7 H6 N2 O3 S2 c1cc2c(cc1....
22 6CB5 Ki = 4.3 uM EV7 C20 H14 N2 O3 c1ccc2cc(c....
23 6B1K Ki = 0.363 uM C9G C17 H13 N5 O2 CN1C=Cc2cc....
24 3L5S - 88X C15 H13 N3 O2 CCC1=CC(=O....
25 6CBH Ki = 0.51 uM EWJ C20 H13 F N2 O3 c1ccc2cc(c....
26 3U18 ic50 = 0.81 uM Y0X C34 H28 N6 O16 S4 COc1c(ccc(....
27 6B2C Ki = 0.09 uM C9Y C18 H12 F N5 O4 c1cc(c(cc1....
28 1MFI Ki = 2.6 uM FHC C9 H6 F O3 c1cc(ccc1C....
50% Homology Family (32)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1LJT ic50 = 7 uM HDI C12 H13 N O4 COC(=O)C[C....
2 3L5R ic50 = 38 nM 47X C15 H10 O5 c1cc(c(cc1....
3 5J7Q Ki = 26.6 uM 6H2 C13 H10 N2 O2 c1ccn2cc(n....
4 5HVT Kd = 0.055 uM NVS C15 H13 N O4 COc1ccc(cc....
5 5B4O - 6DQ C13 H8 N2 O S c1ccc2c(c1....
6 1GCZ Ki = 7.4 uM YZ9 C12 H10 O5 CCOC(=O)C1....
7 3L5P - 428 C9 H11 N3 O CC(C)c1cn2....
8 5HVS Kd = 0.071 uM 65V C24 H15 F N4 O4 c1cc(cc(c1....
9 6B1C Ki = 0.075 uM C9J C17 H12 F N5 O2 CN1C=Cc2cc....
10 3L5T - 956 C20 H18 N4 O2 S CN1c2ccccc....
11 3IJJ - EN1 C9 H8 O4 c1cc(ccc1/....
12 6CBG Ki = 113 uM EWG C10 H8 N2 O2 c1cc(cc(c1....
13 4K9G - 1Q1 C12 H12 F N O3 CC(=O)C[C@....
14 3IJG Kd = 54 uM AVR C13 H17 N3 O C[C@H](C(=....
15 4WRB Ki = 0.65 uM 3TW C20 H18 N4 O3 COCCOc1ccc....
16 1CA7 - ENO C9 H8 O4 c1cc(ccc1C....
17 2OOH ic50 = 1.3 uM OX3 C14 H17 N O3 c1cc(ccc1C....
18 2OOZ ic50 = 7 uM OX5 C13 H17 N O3 CC(C)(C)CC....
19 3DJI - 3E1 C16 H16 N2 O4 CC(=O)Nc1c....
20 6CBF Ki = 6.8 uM EWD C16 H12 N2 O3 c1ccc(cc1)....
21 3L5U - ZEC C7 H6 N2 O3 S2 c1cc2c(cc1....
22 6CB5 Ki = 4.3 uM EV7 C20 H14 N2 O3 c1ccc2cc(c....
23 6B1K Ki = 0.363 uM C9G C17 H13 N5 O2 CN1C=Cc2cc....
24 3L5S - 88X C15 H13 N3 O2 CCC1=CC(=O....
25 6CBH Ki = 0.51 uM EWJ C20 H13 F N2 O3 c1ccc2cc(c....
26 3U18 ic50 = 0.81 uM Y0X C34 H28 N6 O16 S4 COc1c(ccc(....
27 6B2C Ki = 0.09 uM C9Y C18 H12 F N5 O4 c1cc(c(cc1....
28 4Q3F - TLA C4 H6 O6 [C@@H]([C@....
29 6C5F Ki = 33 uM 7L9 C14 H9 N O6 c1cc(cc(c1....
30 3RF5 Ki = 2.37 uM FUZ C12 H11 N O3 c1ccc(c(c1....
31 3RF4 Ki = 0.56 uM FUN C12 H11 Cl N2 O5 S c1cc(oc1)C....
32 1MFI Ki = 2.6 uM FHC C9 H6 F O3 c1cc(ccc1C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FHC; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 FHC 1 1
2 EN1 0.512821 0.68
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1MFI; Ligand: FHC; Similar sites found with APoc: 323
This union binding pocket(no: 1) in the query (biounit: 1mfi.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 5CLO NS8 None
2 3EM0 CHD None
3 3QXV MTX None
4 2PWY SAH None
5 2J9C ATP None
6 3LAD FAD None
7 5VM0 9EG None
8 5MT9 ARG None
9 5MT9 SRO None
10 1Z3C SA8 None
11 2VHW NAI None
12 3NCQ ATP None
13 2Q0L FAD None
14 3A1C ACP None
15 2J9D ADP None
16 4HVA 4HV None
17 4KRI SAH None
18 5VSM MET None
19 4YAG NAI None
20 2GQS C2R None
21 4PIO SAH None
22 1U1I NAD None
23 1O51 ADP None
24 1V3S ATP None
25 3FUU ADN None
26 5VSM 5AD None
27 1FLM FMN None
28 4USI ATP None
29 2J9D AMP None
30 3DXY SAM None
31 1QD0 RR6 None
32 3H4V NAP None
33 3S0E EOL None
34 2TPS TPS None
35 5N0L ILE None
36 5XDT ZI7 None
37 1GYY FHC 1.31579
38 5HV0 AKG 1.75439
39 3G89 SAM 1.75439
40 3LKZ SFG 1.75439
41 3NHT U46 1.75439
42 3NJ4 NAD 2.63158
43 4DQ2 BTX 2.63158
44 1B7A OPE 2.63158
45 5CUQ NSC 2.63158
46 4LAE 1VM 2.63158
47 4LAE NAP 2.63158
48 3LF0 ATP 2.63158
49 1GT4 UNA 2.63158
50 5L7G 6QE 2.63158
51 2BFR ADP 2.63158
52 1U6R ADP 3.50877
53 3QSB 743 3.50877
54 3R5Y F42 3.50877
55 5U8U FAD 3.50877
56 3HCH RSM 3.50877
57 3TAY MN0 3.50877
58 4ZCC FAD 3.50877
59 3LXK MI1 3.50877
60 4NJH SAM 3.50877
61 2FB3 MET 3.50877
62 2FB3 5AD 3.50877
63 2FB3 GTP 3.50877
64 4NJH 2K8 3.50877
65 5GXU FAD 3.50877
66 2JAP NDP 3.50877
67 1ZM1 BGC BGC BGC 3.50877
68 5DNK SAH 3.50877
69 3JZ4 NAP 3.50877
70 1JE1 GMP 4.38596
71 3R5Z F42 4.38596
72 5F7J ADE 4.38596
73 1PN0 IPH 4.38596
74 4JDR FAD 4.38596
75 1PN0 FAD 4.38596
76 3EYA TDP 4.38596
77 5VM6 9EG 4.38596
78 2C7G ODP 4.38596
79 5E9W SAH 4.38596
80 4EIL FOL 4.38596
81 2P41 SAH 4.38596
82 3A5Z KAA 4.38596
83 1I8T FAD 4.38596
84 4J75 TYM 4.38596
85 2P4S DIH 4.38596
86 2YAK OSV 4.38596
87 5X1M DHB 4.38596
88 5X1M THG 4.38596
89 4DQL FAD 4.38596
90 1KPG SAH 4.38596
91 4N02 FNR 4.38596
92 4IO2 GLU 4.38596
93 3LJU IP9 4.38596
94 6H8S FSZ 4.38596
95 3A5Y KAA 4.38596
96 5VL2 9EG 5.26316
97 1M15 ADP 5.26316
98 1M15 ARG 5.26316
99 3TEG DAH 5.26316
100 5JCM NAD 5.26316
101 5JCM ISD 5.26316
102 3TTZ 07N 5.26316
103 5JCM FAD 5.26316
104 1RHC F42 ACN 5.26316
105 1KZN CBN 5.26316
106 2E7Z MGD 5.26316
107 1X14 NAD 5.26316
108 4DVR 0LY 5.26316
109 3R75 PYR 5.26316
110 4M38 SAH 5.26316
111 3DMH GMP 5.26316
112 3DMH SAM 5.26316
113 1VA6 ADP 5.26316
114 1VA6 P2S 5.26316
115 5YGE GLU 5.26316
116 3CZ7 ACO 5.26316
117 1JIL 485 5.26316
118 2O3Z AI7 5.26316
119 2ZW5 COA 5.26316
120 2ZFN ACO 5.26316
121 5JJR SAH 5.26316
122 4HA9 NDP 5.26316
123 1KPH SAH 5.26316
124 3KYF 5GP 5GP 5.26316
125 6H1U ASP 5.26316
126 3LU1 UD2 5.26316
127 1UVC STE 5.49451
128 4I53 1C1 6.14035
129 5ETJ IM5 6.14035
130 4MIB 28M 6.14035
131 2A0W DIH 6.14035
132 5G48 1FL 6.14035
133 1KDK DHT 6.14035
134 5M67 NAD 6.14035
135 5M67 3D1 6.14035
136 5M67 ADE 6.14035
137 5O3Q CMP 6.14035
138 1Y8Q ATP 6.14035
139 4B2Z P5S 6.14035
140 1NW4 IMH 6.14035
141 2B9W FAD 6.14035
142 1F5F DHT 6.14035
143 2OBD PCW 6.14035
144 4NRT 2NG 6.14035
145 1W96 S1A 6.14035
146 1HYH NAD 6.14035
147 4QAR ADE 6.14035
148 3FAL REA 6.14035
149 1E6E FAD 6.14035
150 1C1X HFA 6.14035
151 1DZK PRZ 6.14035
152 5KJW 53C 6.14035
153 2G5C NAD 6.14035
154 4USQ FAD 6.14035
155 2NXE SAM 6.14035
156 4TW7 37K 6.14035
157 3FAL LO2 6.14035
158 2OJW ADP 6.14035
159 3DJF BC3 7.01754
160 1E4E ADP 7.01754
161 4RF7 ARG 7.01754
162 2VT3 ATP 7.01754
163 5GK9 ACO 7.01754
164 4XIZ LPP 7.01754
165 3UBM COA 7.01754
166 4S28 AIR 7.01754
167 4S28 SAH 7.01754
168 3AB1 FAD 7.01754
169 5BWD FUM 7.01754
170 2CWH PYC 7.01754
171 3PPM JG1 7.01754
172 3E9I XAH 7.01754
173 2A8Y MTA 7.01754
174 1RSG FAD 7.01754
175 4FN4 NAD 7.01754
176 1P1C SAH 7.01754
177 2J0B UDP 7.01754
178 4FE2 AIR 7.01754
179 3WR7 COA 7.01754
180 1EQ2 NAP 7.01754
181 2ISJ FMN 7.01754
182 3OND ADN 7.89474
183 3OND NAD 7.89474
184 5DQ8 FLF 7.89474
185 5G3U FDA 7.89474
186 5G3U ITW 7.89474
187 3UR0 SVR 7.89474
188 1NAA ABL 7.89474
189 4BG4 ADP 7.89474
190 4LOO SB4 7.89474
191 1T9D PYD 7.89474
192 3OQJ 3CX 7.89474
193 5WKC AUJ 7.89474
194 1TPY SAH 7.89474
195 1NAA 6FA 7.89474
196 3QPB URA 7.89474
197 5MDH NAD 7.89474
198 1ZDQ MSM 7.89474
199 3EVF GTA 7.89474
200 3EVF SAH 7.89474
201 1G2O IMH 7.89474
202 6CDO ALA VAL GLY ILE GLY ALA VAL PHE 7.89474
203 4OTH DRN 7.89474
204 3DLG GWE 7.89474
205 3EPO MP5 7.89474
206 1C3X 8IG 7.89474
207 2WCJ M21 7.89474
208 3SSO SAH 7.89474
209 4X6F 3XU 8.77193
210 5TT6 ATP 8.77193
211 5ULP KB1 8.77193
212 5T8U LPA 8.77193
213 1COY AND 8.77193
214 1COY FAD 8.77193
215 3T4L ZEA 8.77193
216 3H0L ADP 8.77193
217 4WOE ADP 8.77193
218 3WQD PLP 999 8.77193
219 3O0Q TTP 8.77193
220 1DL5 SAH 8.77193
221 4R57 ACO 8.77193
222 4RYV ZEA 8.77193
223 3KXC PLM 8.77193
224 6ES0 BW8 8.77193
225 3D91 REM 9.64912
226 3O9L LPN 9.64912
227 2ZFU SAH 9.64912
228 4OYA 1VE 9.64912
229 1VMK GUN 9.64912
230 3MF2 AMP 9.64912
231 4B0T ADP 9.64912
232 5MRH Q9Z 9.64912
233 4KWD JF2 9.64912
234 6G9I CXX 9.64912
235 3LZW FAD 9.64912
236 5YSN 5AD 9.64912
237 5Y8L NAD 9.64912
238 5EB4 FAD 9.64912
239 5KVA SAM 10.5263
240 2IV2 2MD 10.5263
241 1ODJ GMP 10.5263
242 5FAL COA 10.5263
243 5FAL SKT 10.5263
244 3GCZ SAM 10.5263
245 5LRT ADP 10.5263
246 5DLY 5D7 11.4035
247 5DLY SAH 11.4035
248 2A8X FAD 11.4035
249 5MW4 5JU 11.4035
250 1M5B BN1 11.4035
251 1RJW ETF 11.4035
252 4M52 FAD 11.4035
253 2NXW TPP 11.4035
254 4DXD 9PC 11.4035
255 2WD7 NAP 11.4035
256 1V8B NAD 11.4035
257 1ZQ9 SAM 11.4035
258 3GD9 GLC BGC BGC BGC 11.4035
259 2B3D FAD 11.4035
260 2YJD YJD 11.4035
261 2BJU IH4 12.2807
262 1R6T TYM 12.2807
263 5JE8 NAD 12.2807
264 5WS9 AMP 12.2807
265 3MHA Z69 12.2807
266 4PAB THG 12.2807
267 3AR5 TM1 12.2807
268 1R6U TYM 12.2807
269 4V15 PLP 12.2807
270 5LY1 PPI 12.2807
271 2BJ4 OHT 12.2807
272 4TV1 36M 12.2807
273 5XNC MTA 13.1579
274 4DA6 GA2 13.1579
275 1WOR RED 14.0351
276 1RYD GLC 14.0351
277 2IVF MGD 14.0351
278 5OF1 SAL 14.0351
279 1L1E SAH 14.0351
280 2TPI ILE VAL 14.0351
281 3B2Q ATP 14.9123
282 3ML1 MGD 14.9123
283 3HNC TTP 14.9123
284 2E2R 2OH 14.9123
285 2WGH DTP 14.9123
286 2IHU TP9 14.9123
287 6A5Y 9CR 14.9123
288 2QE0 NAP 15.7895
289 3BMN NAP 15.7895
290 3JQ9 NAP 15.7895
291 1V59 FAD 15.7895
292 4CM9 NAP 15.7895
293 4CM8 NAP 15.7895
294 3BMO NAP 15.7895
295 4CM4 NAP 15.7895
296 4CMI NAP 15.7895
297 3JQ8 NAP 15.7895
298 3JQG NAP 15.7895
299 5JDI NAP 15.7895
300 3JQF NAP 15.7895
301 4CLR NAP 15.7895
302 6GAR FAD 15.7895
303 5K6A NAP 15.7895
304 3JQB NAP 15.7895
305 5JCJ NAP 15.7895
306 4CME NAP 15.7895
307 5M90 JIF 16.6667
308 5AAV GW5 16.6667
309 1KGI T4A 17.5439
310 5LGD PLM 17.5439
311 6CC0 EWM 18.4211
312 1ZEM NAD 19.2982
313 1KQF MGD 19.2982
314 1XVV CCQ 19.2982
315 1SR7 MOF 19.2982
316 3RNM FAD 21.0526
317 1SDW IYT 21.0526
318 5W5R PYR 21.9298
319 1VGR COA 22.807
320 2VJM COA 22.807
321 4ITH RCM 23.6842
322 6B92 SAH 28.9474
323 6GFK SAH 28.9474
324 3GAC ENO 50
Pocket No.: 2; Query (leader) PDB : 1MFI; Ligand: FHC; Similar sites found with APoc: 123
This union binding pocket(no: 2) in the query (biounit: 1mfi.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 4POO SAM None
2 2FKA BEF None
3 4PIO AVI None
4 1RV1 IMZ None
5 1QD1 FON None
6 1WAP TRP None
7 1QAW TRP None
8 2GC0 PAN None
9 3OII SAH None
10 3I9L N1C 2.63158
11 4E5N NAD 2.63158
12 5XLY C2E 2.63158
13 5ML3 DL3 2.63158
14 1G0N PHH 2.63158
15 1G0N NDP 2.63158
16 4QLX FMN 2.63158
17 5X3D 7XL 2.63158
18 4L80 1VU 2.63158
19 2V0U FMN 2.63158
20 3A4V PYR 2.63158
21 5DX0 SFG 3.50877
22 5DX8 SFG 3.50877
23 5DWQ SFG 3.50877
24 4ZBR NPS 3.50877
25 4ZBR DIF 3.50877
26 5D48 L96 3.50877
27 3D72 FAD 3.50877
28 1T90 NAD 3.50877
29 1QY1 PRZ 3.50877
30 2JAH NDP 3.50877
31 1O9J NAD 3.50877
32 5U19 827 4.38596
33 5U19 SAH 4.38596
34 3SAO DBH 4.38596
35 2C7G FAD 4.38596
36 1ZNY GDP 4.38596
37 4JWH SAH 4.38596
38 5EJL C2E 4.38596
39 6EOM ALA LYS 4.38596
40 1VRP ADP 4.38596
41 1HXD BTN 4.38596
42 5UIU 8CG 4.38596
43 1UP7 NAD 4.38596
44 5A07 GDP 4.38596
45 4RJK TPP 4.38596
46 4RT1 C2E 4.46429
47 1VCE SAH 5.26316
48 1WNG SAH 5.26316
49 3HKW IX6 5.26316
50 2FR6 CTN 5.26316
51 4EMV 0R9 5.26316
52 3IX9 MTX 5.26316
53 1LSH PLD 5.26316
54 2FR6 URI 5.26316
55 4I54 1C1 6.14035
56 4X9X OLA 6.14035
57 2O07 SPD 6.14035
58 2O07 MTA 6.14035
59 3T50 FMN 6.14035
60 3GGO NAI 6.14035
61 1BW9 PPY 6.14035
62 4RW3 IPD 6.14035
63 2DXU BT5 6.14035
64 1O5R FR9 6.14035
65 4L9Z COA 6.14035
66 2XMY CDK 7.01754
67 5E1M SAH 7.01754
68 5HWV MBN 7.01754
69 2IXB NAD 7.01754
70 5JWC FAD 7.01754
71 3MGB PAP 7.89474
72 2E5A LAQ 7.89474
73 2P1O IHP 7.89474
74 2P1O NLA 7.89474
75 3EFS BTN 7.89474
76 2VAR AMP 7.89474
77 3O0Q ADN 8.77193
78 3O0Q GDP 8.77193
79 3ORF NAD 8.77193
80 2I7C AAT 8.77193
81 3B6R ADP 8.77193
82 4CYI ATP 8.77193
83 6A1G 9OL 8.77193
84 3GRU AMP 9.64912
85 1NV8 MEQ 9.64912
86 1NV8 SAM 9.64912
87 3TCT 3MI 9.64912
88 3TE4 ACO 9.64912
89 4E2J MOF 9.64912
90 3JQ3 ADP 9.64912
91 2RHQ GAX 9.64912
92 2JB2 FAD 10.5263
93 2JB2 PHE 10.5263
94 4XZ3 COA 10.5263
95 5Z2L NDP 11.4035
96 5H9Y BGC BGC BGC BGC 11.4035
97 3OLL EST 11.4035
98 2C42 PYR 12.2807
99 2C42 TPP 12.2807
100 5Y4R C2E 12.2807
101 2OHH FMN 12.2807
102 5C8W PCG 12.2807
103 2GOO NDG 13.1579
104 1BZL FAD 14.0351
105 4WO4 JLS 14.9123
106 3JQA NAP 15.7895
107 4CLO NAP 15.7895
108 1JGT APC 16.6667
109 1JGT CMA 16.6667
110 6H39 FGY 16.6667
111 2QE4 JJ3 16.6667
112 4XZ6 TMO 16.6667
113 5CIC 51R 16.6667
114 2RKV COA 17.5439
115 2RKV ZBA 17.5439
116 1VJY 460 18.4211
117 1MXH NAP 19.2982
118 1MXH DHF 19.2982
119 2Q1H AS4 20.1754
120 5IM3 DTP 21.0526
121 2ZBA COA 25.4386
122 4DD8 BAT 28.0702
123 2Z3Y F2N 31.5789
Pocket No.: 3; Query (leader) PDB : 1MFI; Ligand: FHC; Similar sites found with APoc: 53
This union binding pocket(no: 3) in the query (biounit: 1mfi.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 1BOB ACO None
2 4M8E 29V None
3 2ART LPA AMP None
4 5HCV 60R None
5 3TFJ THG None
6 5LHT TIH None
7 2A3I C0R None
8 5XDT MB3 None
9 3T34 GDP 1.75439
10 1EIX BMQ 1.75439
11 4H8N NDP 2.63158
12 3OJI PYV 2.63158
13 5WL1 D3D 3.50877
14 5WL1 CUY 3.50877
15 2QV6 GTP 3.50877
16 1GQ2 NAP 3.50877
17 2YG3 FAD 3.50877
18 3WRB GDE 3.50877
19 3G08 FEE 4.0404
20 3EVG SAH 4.38596
21 2JLD AG1 4.38596
22 5EFW FMN 5
23 1B8O IMH 5.26316
24 1G8K MGD 5.26316
25 4M73 SAH 5.26316
26 4M73 M72 5.26316
27 1IDA 0PO 6.06061
28 3X0D SAH 6.14035
29 6CEN ACE GLY VAL NLE ARG ILE NH2 6.14035
30 3IA4 MTX 6.14035
31 3EWP APR 6.14035
32 1UKZ AMP 6.14035
33 1KJ1 MAN 6.42202
34 1JG3 ADN 7.01754
35 2RCU BUJ 7.01754
36 5E1M PRO PRO LYS ARG ILE ALA 7.01754
37 1X87 NAD 7.01754
38 2VAR ANP 7.89474
39 4XYM COA 10.5263
40 3WG6 NDP 10.5263
41 4R74 F6P 11.4035
42 5F3I 5UJ 12.2807
43 1GVF PGH 13.1579
44 2IVF MD1 14.0351
45 5DEP UD1 14.0351
46 2OO0 PLP 14.0351
47 4XTX 590 14.0351
48 2IHT TPP 14.9123
49 3BMQ NAP 15.7895
50 3JQ7 NAP 15.7895
51 3NRR D16 19.2982
52 4A0M NAD 20.1754
53 2B8T THM 32.4561
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