Receptor
PDB id Resolution Class Description Source Keywords
1M6Y 1.9 Å EC: 2.1.1.- CRYSTAL STRUCTURE ANALYSIS OF TM0872, A PUTATIVE SAM-DEPENDE METHYLTRANSFERASE, COMPLEXED WITH SAH THERMOTOGA MARITIMA SAM-DEPENDENT METHYLTRANSFERASE FOLD PROTEIN-COFACTOR PRODUCOMPLEX STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIAMIDWEST CENTER FOR STRUCTURAL GENOMICS MCSG TRANSFERASE
Ref.: CRYSTAL COMPLEXES OF A PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RE TYPICAL ADOMET BINDING DOMAIN AND A SUBSTRATE RECOG DOMAIN PROTEIN SCI. V. 12 1432 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:401;
B:402;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
SO4 A:500;
B:501;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1N2X 1.9 Å EC: 2.1.1.- CRYSTAL STRUCTURE ANALYSIS OF TM0872, A PUTATIVE SAM- DEPENDENT METHYLTRANSFERASE, COMPLEXED WITH SAM THERMOTOGA MARITIMA SAM-DEPENDENT METHYLTRANSFERASE FOLD PROTEIN-SAM METHYL DONOR COMPLEX STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTER FOR STRUCTURAL GENOMICS MCSG
Ref.: CRYSTAL COMPLEXES OF A PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE REVEAL A TYPICAL ADOMET BINDING DOMAIN AND A SUBSTRATE RECOGNITION DOMAIN PROTEIN SCI. V. 12 1432 2003
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 57 families.
1 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 50 families.
1 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3TKA - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
4 1WG8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1N2X; Ligand: SAM; Similar sites found: 402
This union binding pocket(no: 1) in the query (biounit: 1n2x.bio2) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1PTR PRB 0.02818 0.40611 None
2 1TDF FAD 0.01617 0.40398 1.3289
3 1TDF NAP 0.03459 0.40253 1.3289
4 4RDH AMP 0.002558 0.4343 1.38889
5 4X9M FAD 0.009895 0.40811 1.43541
6 2EJU SAH 0.000006989 0.49464 1.66113
7 3VSE SAH 0.00002428 0.44906 1.66113
8 4HXY NDP 0.003976 0.41634 1.66113
9 2CDU FAD 0.005504 0.41503 1.66113
10 5BVA FAD 0.0123 0.40759 1.66113
11 1JJ7 ADP 0.01864 0.42306 1.92308
12 5ITV NAI 0.001707 0.43049 1.96078
13 5FJN FAD 0.004782 0.42382 1.97368
14 5FJN BE2 0.005525 0.42382 1.97368
15 3PT9 SAH 0.0000002088 0.55004 1.99336
16 2YX1 SFG 0.0000006081 0.50754 1.99336
17 1BZL FAD 0.001768 0.4739 1.99336
18 1LVL NAD 0.0005537 0.44722 1.99336
19 1MO9 KPC 0.005179 0.44557 1.99336
20 1MO9 FAD 0.005703 0.44306 1.99336
21 5T67 SAH 0.001854 0.43975 1.99336
22 5T67 JHZ 0.002453 0.43938 1.99336
23 3CGD NAD 0.01629 0.42108 1.99336
24 3CGD FAD 0.01629 0.42108 1.99336
25 3CGD COA 0.01629 0.42108 1.99336
26 4C3Y FAD 0.006067 0.41834 1.99336
27 3IHG FAD 0.003126 0.41673 1.99336
28 4D7E FAD 0.005629 0.41461 1.99336
29 4C3Y ANB 0.009362 0.41454 1.99336
30 4MO2 FDA 0.007403 0.41056 1.99336
31 3NUG NAD 0.003692 0.41641 2.02429
32 2AOT SAH 0.00006712 0.44382 2.05479
33 1JQD SAH 0.0005141 0.40896 2.05479
34 4YMH SAH 0.000447 0.43558 2.08333
35 3MBI HSX 0.003302 0.44741 2.09059
36 4U60 SIA GAL BGC NGA GAL 0.03333 0.40041 2.14286
37 5KVA SAM 0.000006487 0.51222 2.15827
38 1GXU 2HP 0.008745 0.42878 2.1978
39 3BGD SAH 0.00006273 0.47791 2.30769
40 3BGD PM6 0.0001294 0.4726 2.30769
41 4UCI SAM 0.0003111 0.43591 2.32558
42 4KRG SAH 0.0002456 0.42929 2.32558
43 4LWP SAH 0.0004594 0.42691 2.32558
44 4BV6 FAD 0.00449 0.42404 2.32558
45 1GOJ ADP 0.02525 0.41499 2.32558
46 2C7G FAD 0.01667 0.40935 2.32558
47 4FWE FAD 0.0108 0.40921 2.32558
48 2C7G ODP 0.01664 0.4087 2.32558
49 1REO FAD 0.01338 0.40144 2.32558
50 3FPF TNA 0.0000752 0.40215 2.34899
51 3FPF MTA 0.0000752 0.40215 2.34899
52 1I9G SAM 0.0000004843 0.55077 2.5
53 3C3Y SAH 0.00006053 0.4634 2.53165
54 1JG3 ADN 0.00005155 0.50088 2.55319
55 1AE1 NAP 0.006646 0.40811 2.5641
56 3RFV 15L 0.001879 0.42294 2.62172
57 3RFV NAI 0.003994 0.41089 2.62172
58 2GDZ NAD 0.005725 0.40711 2.62172
59 4PNE SAH 0.00009649 0.47033 2.65781
60 5DX1 SFG 0.000143 0.46723 2.65781
61 5DWQ SFG 0.0001758 0.4617 2.65781
62 5DX0 SFG 0.0002581 0.45672 2.65781
63 1FEC FAD 0.001603 0.44847 2.65781
64 5DXA SFG 0.0004633 0.44269 2.65781
65 5DX8 SFG 0.0004758 0.44223 2.65781
66 3UCL NAP 0.007977 0.43112 2.65781
67 3UCL CYH 0.007272 0.43112 2.65781
68 3UCL FAD 0.007272 0.43112 2.65781
69 1PN0 FAD 0.004377 0.43004 2.65781
70 1PN0 IPH 0.004574 0.43004 2.65781
71 1N4W FAD 0.004714 0.42504 2.65781
72 2V6G NAP 0.004396 0.41323 2.65781
73 5F8F SFG 0.0008711 0.4029 2.65781
74 3LRE ADP 0.03845 0.40273 2.65781
75 5JE8 NAD 0.002594 0.40098 2.65781
76 5G3U FDA 0.0132 0.40073 2.65781
77 1NFQ NAI 0.007638 0.40435 2.69231
78 1Q0S SAH 0.0000001199 0.59079 2.7027
79 2DPM SAM 0.0000008164 0.54806 2.8169
80 1C3V PDC 0.009564 0.43028 2.85714
81 4IF4 BEF 0.005393 0.43858 2.88462
82 5MPT SAH 0.000008916 0.4902 2.99003
83 3L9W AMP 0.00191 0.42844 2.99003
84 4RPL 3UC 0.008861 0.4284 2.99003
85 2DTX BMA 0.003253 0.4281 2.99003
86 3L9W GSH 0.001685 0.42791 2.99003
87 1UXG NAD 0.00328 0.42688 2.99003
88 4RPL FAD 0.0116 0.42116 2.99003
89 5BUK FAD 0.007872 0.41614 2.99003
90 4XQC NAD 0.01127 0.40839 2.99003
91 2XVE FAD 0.03005 0.40024 2.99003
92 3FZG SAM 0.001727 0.44214 3
93 1XHL NDP 0.005245 0.41126 3.0303
94 2ZL4 ALA ALA ALA ALA 0.03053 0.40563 3.06122
95 1GET FAD 0.01347 0.41939 3.11111
96 1GET NAP 0.01428 0.41939 3.11111
97 4N49 SAM 0.00009195 0.46275 3.32226
98 4TQG NDP 0.001962 0.42515 3.32226
99 4M52 FAD 0.005277 0.42195 3.32226
100 1FL2 FAD 0.005731 0.41744 3.32226
101 1I8T FAD 0.006615 0.41474 3.32226
102 1GPE FAD 0.00986 0.41269 3.32226
103 1GR0 NAD 0.008496 0.40473 3.32226
104 2YVF FAD 0.0261 0.40306 3.32226
105 2YVF NAD 0.02976 0.40105 3.32226
106 3WGT FAD 0.02064 0.40004 3.32226
107 3WGT QSC 0.02147 0.40004 3.32226
108 2JBH 5GP 0.01026 0.42251 3.55556
109 2GL0 ADN 0.02767 0.40466 3.59281
110 2BGM NAJ 0.00242 0.41842 3.59712
111 3CTY FAD 0.001491 0.44795 3.65448
112 4D04 FAD 0.008232 0.42736 3.65448
113 4D04 NAP 0.008232 0.42736 3.65448
114 1ELI PYC 0.003487 0.42573 3.65448
115 3GXO SAH 0.003998 0.4254 3.65448
116 2HQM FAD 0.005592 0.42084 3.65448
117 1SOW NAD 0.005424 0.41064 3.65448
118 2RGJ FAD 0.008717 0.40311 3.65448
119 3GWZ SAH 0.0008376 0.40278 3.65448
120 3LXD FAD 0.01139 0.40039 3.65448
121 4II2 ATP 0.0004755 0.43483 3.68098
122 4CS9 AMP 0.01641 0.4246 3.7037
123 2HNK SAH 0.0000653 0.46841 3.76569
124 4RL4 PPV 0.006123 0.43774 3.77358
125 2CBZ ATP 0.02535 0.41509 3.79747
126 4ZCC NAI 0.02316 0.40005 3.86905
127 4ZCC FAD 0.02316 0.40005 3.86905
128 1T57 FMN 0.004051 0.40115 3.8835
129 1I1N SAH 0.000007229 0.52446 3.9823
130 4J36 1HR 0.003401 0.43126 3.98671
131 4J36 FAD 0.002202 0.42845 3.98671
132 1Y8Q ATP 0.000886 0.42636 3.98671
133 2R4J 13P 0.006569 0.42543 3.98671
134 3UOY NAP 0.01818 0.41394 3.98671
135 3UOY FAD 0.01818 0.41394 3.98671
136 1XHC FAD 0.005875 0.41381 3.98671
137 4EIP FAD 0.01434 0.40631 3.98671
138 4EIP K2C 0.01434 0.40631 3.98671
139 4GUT FAD 0.01273 0.40861 4.03226
140 4HSU FAD 0.01821 0.40005 4.03226
141 5GM1 SAH 0.00008844 0.47186 4.0404
142 3LKZ SFG 0.000003577 0.51083 4.04984
143 3HVJ 705 0.00005039 0.50372 4.0724
144 2A14 SAH 0.002167 0.41195 4.18251
145 2PXX SAH 0.0001337 0.4493 4.18605
146 4DMG SAM 0.0000163 0.54854 4.31894
147 1NW5 SAM 0.000005899 0.5019 4.31894
148 2WPF FAD 0.002774 0.46405 4.31894
149 2WPF WPF 0.004058 0.45756 4.31894
150 3KLJ FAD 0.005058 0.41314 4.31894
151 3TKY SAH 0.001382 0.41199 4.31894
152 5KMS FAD 0.009704 0.40445 4.31894
153 3GMB FAD 0.01083 0.40023 4.31894
154 1KNR FAD 0.01505 0.40015 4.31894
155 2PX8 SAH 0.00001034 0.48569 4.46097
156 1IY8 NAD 0.004547 0.41261 4.49438
157 4BLW AMP 0.000004891 0.54244 4.49827
158 4BLW SAH 0.000003826 0.53383 4.49827
159 5JGL SAM 0.00005062 0.45294 4.49827
160 5JJR SAH 0.000002114 0.5618 4.65116
161 1V59 FAD 0.003661 0.43171 4.65116
162 1UWK NAD 0.00387 0.43064 4.65116
163 1X87 NAD 0.001203 0.42589 4.65116
164 2BRY FAD 0.002733 0.42448 4.65116
165 4TXI FAD 0.002697 0.42345 4.65116
166 3C6K SPD 0.003892 0.42149 4.65116
167 3C6K MTA 0.003892 0.42149 4.65116
168 1V59 NAD 0.0003465 0.41604 4.65116
169 1QO8 FAD 0.007294 0.41579 4.65116
170 4CNK FAD 0.007065 0.41248 4.65116
171 1OBB NAD 0.001991 0.41086 4.65116
172 4MIG G3F 0.01337 0.40926 4.65116
173 2E5V FAD 0.01135 0.40825 4.65116
174 5J60 FAD 0.01239 0.40385 4.65116
175 3FGZ BEF 0.004321 0.44164 4.6875
176 2BZG SAH 0.00001745 0.47732 4.74138
177 4YAG NAI 0.009758 0.41024 4.84429
178 5CUQ NSC 0.000006079 0.53503 4.86891
179 3LCV SAM 0.003059 0.40944 4.98221
180 5MW4 5JU 0.0000878 0.49724 4.98339
181 3QOX SAH 0.00002319 0.49543 4.98339
182 5JCA FAD 0.0014 0.44714 4.98339
183 5JCA NDP 0.003898 0.44155 4.98339
184 3ICT FAD 0.006085 0.41424 4.98339
185 3ICR FAD 0.007093 0.41137 4.98339
186 3ICS FAD 0.00789 0.41041 4.98339
187 2QQF A1R 0.003536 0.4101 4.98339
188 2OD9 A1R NCA 0.00585 0.40672 4.98339
189 3NT6 FAD 0.01175 0.40292 4.98339
190 4NTC FAD 0.01516 0.40094 4.98339
191 2ZIF SAM 0.0000006914 0.53774 5.05051
192 2WA2 SAM 0.000001858 0.50631 5.07246
193 3MB5 SAM 0.00000022 0.57745 5.09804
194 1XCL SAH 0.0005793 0.40439 5.10638
195 2JAH NDP 0.008099 0.40205 5.26316
196 2P41 SAH 0.000001771 0.56517 5.31561
197 4KRI SAH 0.00004321 0.47361 5.31561
198 3GD4 FAD 0.005316 0.4333 5.31561
199 3GD4 NAD 0.008267 0.4333 5.31561
200 5BR7 FAD 0.01217 0.41893 5.31561
201 5BR7 FLC 0.01445 0.4155 5.31561
202 2NVK FAD 0.007718 0.41377 5.31561
203 4TM3 FAD 0.02136 0.41126 5.31561
204 4YNU FAD 0.01023 0.41111 5.31561
205 4YNU LGC 0.01354 0.40902 5.31561
206 3OJO NAD 0.004575 0.40233 5.31561
207 2V3A FAD 0.01312 0.40084 5.31561
208 3EVF SAH 0.00001207 0.43183 5.41516
209 3EVF GTA 0.00001522 0.41598 5.41516
210 5XVK SAH 0.001608 0.42078 5.6338
211 1G55 SAH 0.0000000116 0.6526 5.64784
212 1U2Z SAH 0.00006224 0.47805 5.64784
213 2AWN ADP 0.00911 0.44551 5.64784
214 5KOK SAH 0.0003053 0.4374 5.64784
215 5KOK S9T 0.00209 0.43066 5.64784
216 5DNK SAH 0.0001521 0.4171 5.64784
217 4AP3 FAD 0.01306 0.41687 5.64784
218 4AP3 NAP 0.01306 0.41687 5.64784
219 2RGO FAD 0.006233 0.41379 5.64784
220 2RAB FAD 0.009119 0.41333 5.64784
221 2RAB NAD 0.0182 0.41333 5.64784
222 4YSX FAD 0.007569 0.41318 5.64784
223 4MOP 2H5 0.01479 0.40957 5.64784
224 5KOK R9T 0.008698 0.40315 5.64784
225 1G6H ADP 0.01851 0.42316 5.83658
226 1D4D FAD 0.003288 0.4319 5.98007
227 1P1C SAH 0.0001406 0.4637 6.03015
228 1I7E IBS 0.02756 0.4081 6.03774
229 1QAN SAH 0.0000008179 0.54805 6.14754
230 5N53 8NB 0.01635 0.4184 6.15385
231 1R18 SAH 0.000002632 0.52757 6.1674
232 5E1M PRO PRO LYS ARG ILE ALA 0.0003028 0.46632 6.22407
233 5E1M SAH 0.0003028 0.46632 6.22407
234 5HJM MTA 0.0001068 0.48206 6.31229
235 4OPC FDA 0.01249 0.43364 6.31229
236 4OPC PGT 0.01435 0.43364 6.31229
237 3ML1 MGD 0.02525 0.40896 6.31229
238 5ULP KB1 0.000002408 0.53766 6.34328
239 3G2O SAM 0.000006541 0.54026 6.35452
240 1MZV AMP 0.004572 0.43548 6.38298
241 2W58 ADP 0.01546 0.42637 6.43564
242 1XTT U5P 0.007257 0.41349 6.48148
243 5N5D SAM 0.0002635 0.43759 6.63717
244 5JCM NAD 0.009222 0.42699 6.64452
245 5JCM FAD 0.009222 0.42699 6.64452
246 5JCM ISD 0.009794 0.42699 6.64452
247 4D86 ADP 0.008247 0.40078 6.64452
248 3P2E SAH 0.0001655 0.46934 6.66667
249 1XTP SAI 0.0001059 0.44892 6.69291
250 2VDV SAM 0.00003751 0.52461 6.91057
251 5E8J SAH 0.0003451 0.47941 6.97674
252 1Q9I TEO 0.005461 0.43205 6.97674
253 5E9W SAH 0.0004184 0.41148 6.97674
254 4NTD FAD 0.008601 0.40879 6.97674
255 3A27 SAM 0.0000204 0.51856 6.98529
256 3T7S SAM 0.00002897 0.46756 7.08955
257 4NEC SAH 0.000318 0.47585 7.19697
258 1O97 FAD 0.004591 0.43472 7.19697
259 1O97 AMP 0.004591 0.43472 7.19697
260 4PIO SAH 0.0001803 0.47589 7.30897
261 4PIO AVI 0.0001966 0.47287 7.30897
262 3LAD FAD 0.003749 0.42844 7.30897
263 2IV2 MGD 0.004209 0.42003 7.30897
264 2DKH FAD 0.003537 0.41973 7.30897
265 2DKH 3HB 0.005074 0.41973 7.30897
266 1E1M FAD 0.01682 0.40777 7.30897
267 2XVF FAD 0.009933 0.40506 7.30897
268 4OBW SAM 0.0002078 0.47429 7.393
269 2YJP CYS 0.03303 0.40332 7.56014
270 1XDS SAM 0.0003337 0.48009 7.6412
271 4USR FAD 0.005693 0.41096 7.6412
272 3JSZ UPG 0.007182 0.40025 7.6412
273 1KPG SAH 0.00005511 0.48474 7.66551
274 1TPY SAH 0.00004449 0.4788 7.66551
275 1KPH SAH 0.00005085 0.47622 7.66551
276 1UAY ADN 0.002394 0.43993 7.85124
277 2ZFU SAH 0.0005177 0.43021 7.90698
278 1TE2 PGA 0.01454 0.42005 7.9646
279 3S1S SAH 0.00000213 0.53747 7.97342
280 5THY SAH 0.000004405 0.51263 7.97342
281 4DCM SAM 0.00009246 0.44161 7.97342
282 4AZW SAM 0.0003084 0.43571 7.97342
283 4AZT SAM 0.0002754 0.43286 7.97342
284 1QZZ SAM 0.0004146 0.40699 7.97342
285 3ELW SAM 0.00001337 0.41082 8
286 3ELW GP3 0.00001653 0.40427 8
287 1VBO MAN MAN MAN 0.02297 0.40521 8.05369
288 5GWX SAR 0.0005078 0.44637 8.09859
289 5GWX SAM 0.0005078 0.44637 8.09859
290 4R6W PC 0.005138 0.43022 8.13953
291 4R6W SAH 0.002108 0.42797 8.13953
292 1HGX 5GP 0.02192 0.40576 8.19672
293 3U31 NAD 0.000277 0.45575 8.27586
294 4BJZ P3A 0.0216 0.41213 8.30565
295 1V6A TRE 0.02513 0.40896 8.30565
296 2VVM FAD 0.01291 0.40307 8.30565
297 1L3I SAH 0.000001077 0.55652 8.33333
298 3AD8 NAD 0.00144 0.43755 8.37438
299 3AD8 PYC 0.02402 0.40774 8.37438
300 3AD8 FAD 0.02402 0.40774 8.37438
301 5E72 SAM 0.00000008159 0.58748 8.63787
302 5JWC FAD 0.003887 0.42037 8.63787
303 4USQ FAD 0.004303 0.41732 8.63787
304 4PPF FLC 0.03626 0.4074 8.63787
305 1DQN IMU 0.01303 0.41724 8.69565
306 3EVG SAH 0.000000684 0.5307 8.72727
307 3GCZ SAM 0.0000007382 0.52841 8.9701
308 5X62 SAH 0.0001267 0.44107 8.9701
309 1T26 NAI 0.005988 0.41954 8.9701
310 5FTW SAH 0.0003988 0.43612 8.98438
311 2GAG NAD 0.001235 0.44403 9.04762
312 2GAG FAD 0.0178 0.40131 9.04762
313 3DXY SAM 0.00004719 0.52638 9.17431
314 3MQ2 SAH 0.0008915 0.40891 9.17431
315 4JLS 3ZE 0.005585 0.44295 9.21053
316 1BC5 SAH 0.00327 0.40826 9.29368
317 5THZ SAH 0.000006926 0.51671 9.30233
318 5FA8 SAM 0.000006458 0.51794 9.31677
319 3VYW SAM 0.00000288 0.54352 9.63455
320 3LST SAH 0.0006555 0.46634 9.63455
321 2O07 MTA 0.001244 0.40802 9.63455
322 2PS1 ORO 0.007948 0.42812 9.73451
323 5MGZ SAH 0.00009301 0.4547 9.74576
324 3BBH SFG 0.01202 0.40001 9.7561
325 1KYQ NAD 0.001154 0.40702 9.85401
326 1ZEM NAD 0.004006 0.40938 9.92366
327 4RSL FAD 0.0006841 0.45383 9.96678
328 1UP7 NAD 0.001318 0.42769 9.96678
329 4A6D SAM 0.002109 0.42632 9.96678
330 2A92 NAI 0.004643 0.41349 9.96678
331 3GDN FAD 0.008282 0.41337 9.96678
332 3GDN HBX 0.01172 0.41337 9.96678
333 3F8D FAD 0.0215 0.41223 9.96678
334 4XUC 43G 0.0006131 0.4533 10.0917
335 4XUC SAM 0.0006131 0.4533 10.0917
336 1VE3 SAM 0.0006146 0.4536 10.1322
337 4YRY FAD 0.004225 0.42617 10.299
338 4YRY NAD 0.0109 0.41628 10.299
339 1V5F FAD 0.02093 0.40933 10.299
340 5LOG SAH 0.0003049 0.438 10.3004
341 3Q87 SAM 0.00007283 0.47528 10.4
342 2PT9 2MH 0.0006406 0.45249 10.5919
343 2PT9 S4M 0.0003454 0.45153 10.5919
344 4REP FAD 0.009744 0.40743 10.6312
345 3H2B SAH 0.00004268 0.46901 10.8374
346 1RP0 AHZ 0.003134 0.4207 10.9155
347 5I39 FAD 0.005032 0.41885 10.9635
348 5U8U FAD 0.01544 0.41604 10.9635
349 2YVJ NAI 0.005597 0.41142 11.0092
350 4YUW S4M 0.002695 0.46703 11.2957
351 4YUW 4JU 0.002754 0.46703 11.2957
352 3S5W FAD 0.002589 0.42289 11.2957
353 1H82 GZZ 0.01605 0.41341 11.2957
354 1H82 FAD 0.01358 0.41341 11.2957
355 1JQ3 AAT 0.0001391 0.41959 11.4865
356 1NVM NAD 0.001685 0.43337 11.5385
357 3A25 SAM 0.0000656 0.49628 11.6279
358 4Z24 FAD 0.01189 0.40648 11.6279
359 3WV8 ATP 0.001385 0.41474 11.9266
360 3NTD FAD 0.009181 0.40756 11.9601
361 2I7C AAT 0.0001784 0.41344 12.0141
362 2OBF SAH 0.00318 0.43157 12.1107
363 2OBF F83 0.00318 0.43157 12.1107
364 4KIB SAH 0.00001278 0.47634 12.2924
365 1F3L SAH 0.0001378 0.46828 12.2924
366 2FKA BEF 0.009915 0.4367 12.4031
367 1Z3C SA8 0.0002785 0.46202 12.4161
368 5JE0 SAH 0.0001793 0.47158 12.5506
369 5JE0 AZ8 0.0001793 0.47158 12.5506
370 3ZNN 4WL 0.02428 0.40258 12.6246
371 3ZNN FAD 0.02428 0.40258 12.6246
372 5BW4 SAM 0.00001411 0.47411 12.7341
373 2F5Z FAD 0.006535 0.4188 12.9568
374 1YY5 FAD 0.007 0.41839 12.9568
375 1RSG FAD 0.007972 0.4141 12.9568
376 3RNM FAD 0.009682 0.4113 12.9568
377 1ZMD NAI 0.002025 0.40796 12.9568
378 1G60 SAM 0.0000001819 0.56001 13.0769
379 3JWH SAH 0.00004456 0.43664 13.3641
380 5XVQ SAH 0.0005476 0.43975 13.3803
381 5TTJ FAD 0.01188 0.40368 13.9535
382 2PWY SAH 0.0000005438 0.56151 14.3411
383 1SQF SAM 0.0000003029 0.59886 14.6179
384 1L1E SAH 0.00005396 0.46999 14.6341
385 3BXO SAM 0.0001776 0.42574 14.6444
386 1DL5 SAH 0.000005507 0.52732 14.9502
387 2GVC FAD 0.007496 0.40589 14.9502
388 1VQW FAD 0.008063 0.40455 14.9502
389 1LSS NAD 0.0008625 0.42377 15
390 1G8K MGD 0.01339 0.42069 15.7895
391 4PLG NAI 0.003632 0.42389 15.9468
392 2V3B FAD 0.01201 0.4015 16.3636
393 4EMJ FAD 0.01116 0.40487 17.757
394 3OU2 SAH 0.00003959 0.47091 18.8073
395 4POO SAM 0.000000000392 0.69212 19.5
396 2HMT NAI 0.003368 0.40469 20.1389
397 1E6E FAD 0.007183 0.41006 20.3125
398 2XVM SAH 0.0002628 0.41515 20.603
399 5EB4 FAD 0.009835 0.40823 24.9169
400 4J56 FAD 0.007581 0.41687 27.193
401 4GQB 0XU 0.00001817 0.50189 40.9091
402 5FA5 MTA 0.0001788 0.43144 45
Pocket No.: 2; Query (leader) PDB : 1N2X; Ligand: SAM; Similar sites found: 31
This union binding pocket(no: 2) in the query (biounit: 1n2x.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2NU5 NAG 0.02607 0.413 None
2 2GUC MAN 0.02609 0.41074 None
3 2HYR BGC GLC 0.03032 0.40514 None
4 4BWL MN9 0.03327 0.40322 1.3289
5 4AU8 Z3R 0.01735 0.40834 2.36486
6 3GEG NAD 0.001791 0.42211 2.42915
7 4EUE NAI 0.007704 0.40146 2.65781
8 1NJR XYL 0.001672 0.40421 2.8169
9 3CQL NAG 0.03866 0.40046 2.88066
10 4YDD MGD 0.03475 0.40073 2.99003
11 4YDD MD1 0.03475 0.40073 2.99003
12 2WSB NAD 0.01293 0.40047 3.14961
13 2Q1S NAI 0.01228 0.40416 3.32226
14 1MV8 NAD 0.005709 0.40019 3.32226
15 4DSG FAD 0.02686 0.40016 3.32226
16 4DSG UDP 0.02686 0.40016 3.32226
17 3VM7 GLC 0.02302 0.41524 3.98671
18 5MZI FYK 0.0236 0.40271 4.98339
19 5MZI FAD 0.02285 0.40271 4.98339
20 2Y6Q I7T 0.01613 0.40153 4.98339
21 2Y6Q FAD 0.007672 0.40153 4.98339
22 2PFY PCA 0.03414 0.40514 5.31561
23 2PFZ PCA 0.04152 0.40006 6.31229
24 3WWX DIA 0.03529 0.40286 6.97674
25 1TLG GAL 0.04169 0.40114 7.2
26 3QVP FAD 0.01084 0.40652 8.63787
27 4FC7 COA 0.01197 0.40376 9.02527
28 4FC7 NAP 0.01197 0.40376 9.02527
29 2O07 SPD 0.001556 0.40086 9.63455
30 3SQP FAD 0.0233 0.43419 10.6312
31 1SQL GUN 0.02309 0.41181 10.9589
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