Receptor
PDB id Resolution Class Description Source Keywords
1LTZ 1.4 Å EC: 1.14.16.1 CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE HAS BOUND IRON (III) AND OXIDIZED CO8 -DIHYDROBIOPTERIN CHROMOBACTERIUM VIOLACEUM OXIDOREDUCTASE HYDROXYLASE PHENYLALANINE DIHYDROBIOPTERINBACTERIAL ENZYME
Ref.: STRUCTURAL COMPARISON OF BACTERIAL AND HUMAN IRON-D PHENYLALANINE HYDROXYLASES: SIMILAR FOLD, DIFFERENT STABILITY AND REACTION RATES. J.MOL.BIOL. V. 320 645 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:401;
Invalid;
none;
submit data
35.453 Cl [Cl-]
FE A:400;
Part of Protein;
none;
submit data
55.845 Fe [Fe+3...
HBI A:500;
Valid;
none;
submit data
239.231 C9 H13 N5 O3 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1LTZ 1.4 Å EC: 1.14.16.1 CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE HAS BOUND IRON (III) AND OXIDIZED CO8 -DIHYDROBIOPTERIN CHROMOBACTERIUM VIOLACEUM OXIDOREDUCTASE HYDROXYLASE PHENYLALANINE DIHYDROBIOPTERINBACTERIAL ENZYME
Ref.: STRUCTURAL COMPARISON OF BACTERIAL AND HUMAN IRON-D PHENYLALANINE HYDROXYLASES: SIMILAR FOLD, DIFFERENT STABILITY AND REACTION RATES. J.MOL.BIOL. V. 320 645 2002
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1LTZ - HBI C9 H13 N5 O3 C[C@@H]([C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1LTZ - HBI C9 H13 N5 O3 C[C@@H]([C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1LTZ - HBI C9 H13 N5 O3 C[C@@H]([C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HBI; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 HBI 1 1
2 44W 0.519231 0.816667
3 PH2 0.464286 0.852459
4 ZSP 0.45 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1LTZ; Ligand: HBI; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1ltz.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
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