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Receptor
PDB id Resolution Class Description Source Keywords
1LN1 2.4 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF HUMAN PHOSPHATIDYLCHOLINE TRANSFER PROT COMPLEX WITH DILINOLEOYLPHOSPHATIDYLCHOLINE HOMO SAPIENS START DOMAIN LIPID BINDING PROTEIN
Ref.: STRUCTURE OF HUMAN PHOSPHATIDYLCHOLINE TRANSFER PRO COMPLEX WITH ITS LIGAND. NAT.STRUCT.BIOL. V. 9 507 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DLP A:2313;
Valid;
none;
submit data
782.082 C44 H80 N O8 P CCCCC...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1LN1 2.4 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF HUMAN PHOSPHATIDYLCHOLINE TRANSFER PROT COMPLEX WITH DILINOLEOYLPHOSPHATIDYLCHOLINE HOMO SAPIENS START DOMAIN LIPID BINDING PROTEIN
Ref.: STRUCTURE OF HUMAN PHOSPHATIDYLCHOLINE TRANSFER PRO COMPLEX WITH ITS LIGAND. NAT.STRUCT.BIOL. V. 9 507 2002
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1LN1 - DLP C44 H80 N O8 P CCCCCC=C/C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1LN1 - DLP C44 H80 N O8 P CCCCCC=C/C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1LN1 - DLP C44 H80 N O8 P CCCCCC=C/C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DLP; Similar ligands found: 73
No: Ligand ECFP6 Tc MDL keys Tc
1 DLP 1 1
2 POV 0.860759 1
3 L9R 0.860759 1
4 PCF 0.769231 0.98
5 MC3 0.769231 0.98
6 PC1 0.769231 0.98
7 PSC 0.758621 0.925926
8 PCW 0.659091 0.925926
9 GP7 0.623656 0.728814
10 3PE 0.619048 0.796296
11 PEK 0.602151 0.728814
12 P3A 0.602151 0.696429
13 EPH 0.58 0.728814
14 LIO 0.574713 0.907407
15 HGX 0.574713 0.907407
16 HGP 0.574713 0.907407
17 PC7 0.574713 0.907407
18 6PL 0.574713 0.907407
19 PLD 0.574713 0.907407
20 D21 0.569767 0.690909
21 PIE 0.568421 0.661017
22 CDL 0.55814 0.730769
23 L9Q 0.554348 0.728814
24 LOP 0.554348 0.728814
25 6OU 0.554348 0.728814
26 XP5 0.551724 0.907407
27 T7X 0.534653 0.622951
28 ZPE 0.526316 0.728814
29 PGW 0.515789 0.666667
30 D3D 0.515789 0.666667
31 PX2 0.511905 0.716981
32 PX8 0.511905 0.716981
33 PGV 0.510417 0.666667
34 DR9 0.510417 0.666667
35 PCK 0.510204 0.859649
36 AGA 0.505495 0.678571
37 P6L 0.505155 0.666667
38 P50 0.5 0.724138
39 OZ2 0.5 0.666667
40 B7N 0.494949 0.622951
41 42H 0.494737 0.892857
42 3PC 0.494505 0.96
43 6PH 0.482353 0.672727
44 LPP 0.482353 0.672727
45 7PH 0.482353 0.672727
46 F57 0.482353 0.672727
47 3PH 0.482353 0.672727
48 7P9 0.476744 0.672727
49 PEV 0.472527 0.711864
50 PEH 0.472527 0.711864
51 PTY 0.472527 0.711864
52 8PE 0.472527 0.711864
53 PEF 0.472527 0.711864
54 9PE 0.467391 0.711864
55 PD7 0.458824 0.672727
56 PEE 0.451613 0.728814
57 PC5 0.450549 0.87037
58 CD4 0.445652 0.672727
59 PGT 0.43617 0.649123
60 LHG 0.43617 0.649123
61 M7U 0.43617 0.672727
62 PFS 0.43617 0.98
63 PIZ 0.435644 0.606557
64 44E 0.435294 0.672727
65 OPC 0.432692 0.909091
66 8ND 0.431818 0.618182
67 P5S 0.427083 0.694915
68 IP9 0.425743 0.606557
69 PII 0.418367 0.606557
70 LAP 0.414894 0.875
71 LPC 0.414894 0.875
72 LP3 0.414894 0.875
73 CN3 0.41 0.672727
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1LN1; Ligand: DLP; Similar sites found with APoc: 233
This union binding pocket(no: 1) in the query (biounit: 1ln1.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 5EZU MYR None
2 4WG0 CHD None
3 5N53 8NB None
4 5Y02 MXN None
5 1UO4 PIH None
6 1NU4 MLA None
7 1OGZ EQU None
8 4OR7 25U None
9 3GWN FAD None
10 2Y2B AH0 1.60428
11 4MZU TYD 1.86916
12 4OSP 2V4 1.86916
13 1SJD NPG 1.86916
14 1ZM1 BGC BGC BGC 1.86916
15 4RYV ZEA 1.93548
16 2VWA PTY 1.9802
17 2VQ5 HBA 1.99005
18 1DZT ATY 2.18579
19 5HCA BGC 2.33645
20 4U0W 16G 2.33645
21 4J25 OGA 2.33645
22 6GN6 MAL 2.33645
23 4V3I ASP LEU THR ARG PRO 2.33645
24 6CGN DA 2.33645
25 4YGF AZM 2.33645
26 5OSW DIU 2.33645
27 2W9S TOP 2.48447
28 6D61 4AA 2.5641
29 5FPX GLY SER SER HIS HIS HIS HIS HIS 2.65487
30 4ZU4 4TG 2.7027
31 3JUQ AJD 2.7027
32 2UW1 GVM 2.80374
33 4AZI OAN 2.80374
34 1Z03 OCH 2.80374
35 4UDK BMA 2.80374
36 4RZB NFQ 2.80374
37 6GIN IR2 2.80374
38 1OJJ GLC GAL 2.80374
39 3B00 16A 2.80374
40 1XIM XYL 2.80374
41 6E08 NAP 2.80374
42 1XW6 GSH 2.80374
43 3O01 DXC 2.80374
44 4KBA 1QM 2.80374
45 4O1Z MXM 2.80374
46 5K21 6QF 2.83688
47 6EVN PRO PRO GLY PRO ALA GLY PRO PRO GLY 2.94118
48 4H6B 10X 3.07692
49 3L1N PLM 3.09278
50 1H0A I3P 3.16456
51 3PNA CMP 3.24675
52 5LX9 OLB 3.27103
53 4LIT AKG 3.27103
54 5L9B AKG 3.27103
55 3HQR OGA 3.27103
56 4D06 NAR 3.27103
57 4TQ3 GPP 3.27103
58 2PX6 DH9 3.27103
59 4Y8D 49J 3.27103
60 5UC9 MYR 3.27103
61 3GXO MQA 3.27103
62 5CXI 5TW 3.44828
63 1NYW DAU 3.5533
64 5V4R MGT 3.7037
65 1ZED PNP 3.73832
66 4L4J NAG NAG BMA MAN NAG 3.73832
67 4MLO PAM 3.73832
68 1NQ7 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 3.73832
69 3SRV S19 3.73832
70 5V3Y 5V8 3.73832
71 3HW5 AMP 3.73832
72 5G48 1FL 3.73832
73 2A1L PCW 3.73832
74 3BRN SRO 3.82166
75 1I06 TZL 3.88889
76 3F8C HT1 3.96825
77 6GR0 F8W 4.02299
78 1QY1 PRZ 4.02299
79 3E3U NVC 4.06091
80 5V3D FCN 4.13793
81 5FPN KYD 4.20561
82 5L6G XYP 4.20561
83 2QCX PF1 4.20561
84 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 4.20561
85 4FFG 0U8 4.20561
86 5Y79 3PG 4.20561
87 5QIN J2V 4.20561
88 5L9V OGA 4.6729
89 2PSJ CEI 4.6729
90 4M1U A2G MBG 4.6729
91 1W3T 3GR 4.6729
92 4MGA 27L 4.6729
93 5OLK DTP 4.6729
94 1PZL MYR 4.6729
95 4RHP PEF 4.68085
96 2I74 MAN MAN MAN MAN 4.7619
97 5B09 4MX 4.80769
98 3KYQ DPV 5.02513
99 2FR3 REA 5.10949
100 1I0B PEL 5.14019
101 2OVW CBI 5.14019
102 4NAO AKG 5.14019
103 1U3D ANP 5.14019
104 3TDC 0EU 5.24934
105 3W9R A8S 5.29101
106 1RL4 BL5 5.31915
107 5NIU 8YZ 5.46875
108 5I0U DCY 5.5
109 5X7Q GLC GLC GLC GLC GLC 5.60748
110 2H8H H8H 5.60748
111 3B9Z CO2 5.60748
112 2XIB DFU 5.60748
113 2HFP NSI 5.60748
114 3JZ0 CLY 5.60748
115 6B9R 2HE 5.60748
116 4KYS VIB 5.60748
117 4CNO 9PY 5.60748
118 2Z77 HE7 5.7554
119 4JH6 FCN 5.7971
120 1OH2 SUC 6.07477
121 1VRP IOM 6.07477
122 4P42 PEE 6.07477
123 3N7S 3N7 6.08696
124 1R6N 434 6.16114
125 1Y9Q MED 6.25
126 2HZQ STR 6.32184
127 5H9P TD2 6.32911
128 3E85 BSU 6.32911
129 1OI6 TMP 6.34146
130 5C1M OLC 6.4
131 5C1M CLR 6.4
132 5C1M 4VO 6.4
133 4ZSI 4R1 6.43275
134 4ZSI GLP 6.43275
135 2IXC TRH 6.43564
136 6B21 C9V 6.54206
137 1P1M MET 6.54206
138 1Q7E MET 6.54206
139 5OCA 9QZ 6.54206
140 5NBP BGC BGC BGC 6.54206
141 4CU1 71S 6.54206
142 2OZ5 7XY 6.54206
143 4F4S EFO 6.57895
144 5JSP DQY 6.96517
145 6CB2 OLC 7.00935
146 3RDE OYP 7.00935
147 5C9J DAO 7.07071
148 5WL1 D3D 7.07071
149 5WL1 CUY 7.07071
150 4F7E 0SH 7.14286
151 1D1G MTX 7.14286
152 3L9R L9R 7.14286
153 2OVD DAO 7.14286
154 3THR C2F 7.47664
155 5M37 9SZ 7.47664
156 5M36 9SZ 7.47664
157 5LWY OLB 7.56302
158 3A8H TAY 7.72947
159 1J78 OLA 7.94393
160 2BCG GER 8.25243
161 5BVB DOG 8.33333
162 2YKL NLD 8.33333
163 5KEW 6SB 8.51064
164 5CHR 4NC 8.75912
165 3TL1 JRO 8.80503
166 1U0A BGC BGC BGC BGC 8.8785
167 5C3R AKG 8.8785
168 5C3R HMU 8.8785
169 4GBD MCF 8.8785
170 4EJ1 FOL 8.95522
171 2P7Q GG6 9.02256
172 5AZC PGT 9.81308
173 4EVQ PHB 9.81308
174 4QXB OGA 9.81308
175 5DYO FLU 9.90566
176 3OCP CMP 10.0719
177 2QL9 CIT 10.3093
178 4ZGM 32M 10.6557
179 5Y80 IRE 10.8108
180 3QRC SCR 10.828
181 5CX6 CDP 11.215
182 4K55 H6P 11.2903
183 4EHQ GBL 11.4865
184 5VNF VAL THR SER VAL VAL 11.6822
185 4TV1 36M 11.6822
186 4LWU 20U 11.7647
187 1NKI PPF 11.8519
188 2WOR 2AN 12
189 5W7B MYR 12.0567
190 2PA7 TYD 12.0567
191 4DOO DAO 12.6829
192 4YMJ 4EJ 13.0841
193 3VQ2 LP4 LP5 MYR DAO 13.1944
194 1MT1 AG2 13.4615
195 5MWE TCE 13.5802
196 2Y69 CHD 13.75
197 6BR9 PGV 14.486
198 3AJH BL3 14.486
199 5EEH P9P 14.486
200 3HUJ AGH 15.311
201 1OW4 2AN 15.5039
202 6GNO XDI 15.5556
203 1U6R IOM 16.3551
204 4UCC ZKW 16.3551
205 3KFF XBT 16.6667
206 3KFF ZBT 16.6667
207 5TZO 7V7 17.0213
208 4MNS 2AX 17.6101
209 6BR8 PGV 17.757
210 2O1V ADP 18.2243
211 3QUZ QUV 18.6603
212 3BY9 SIN 18.6916
213 5TPV TYD 19.6078
214 5ZCO PGV 19.6429
215 5W97 CHD 19.6429
216 2DYR PGV 19.6429
217 5Z84 CHD 19.6429
218 2DYS PGV 19.6429
219 5ZCO CHD 19.6429
220 5ZCO PEK 19.6429
221 5Z84 PEK 19.6429
222 1QKQ MAN 19.7183
223 4OB1 BUB 20.0935
224 4OFG PCG 20.1389
225 4OB0 PBC 20.4762
226 5XIO HFG 21.028
227 3RUG DB6 22.0588
228 3GGF GVD 23.3645
229 4RJD TFP 24.2424
230 4OGQ 7PH 24.3243
231 4OGQ UMQ 24.3243
232 4OGQ 1O2 24.3243
233 3QUG GIX 25.3968
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