Receptor
PDB id Resolution Class Description Source Keywords
1L7H 1.85 Å EC: 3.2.1.18 CRYSTAL STRUCTURE OF R292K MUTANT INFLUENZA VIRUS NEURAMINID COMPLEX WITH BCX-1812 INFLUENZA A VIRUS N9 NEURAMINIDASE HYDROLASE INFLUENZA GLYCOSYLATED PROTEIN1812 R292K MUTANT
Ref.: STRUCTURAL STUDIES OF THE RESISTANCE OF INFLUENZA V NEURAMINDASE TO INHIBITORS. J.MED.CHEM. V. 45 2207 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BCZ A:801;
Valid;
none;
submit data
328.407 C15 H28 N4 O4 CCC(C...
CA A:997;
A:998;
A:999;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
GOL A:701;
A:702;
A:703;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
NAG A:1146;
Part of Protein;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG A:1086;
Part of Protein;
none;
submit data
408.404 n/a O=C(N...
NAG NAG BMA MAN MAN MAN MAN A:1200;
Part of Protein;
none;
submit data
1219.11 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4MWV 2 Å EC: 3.2.1.18 ANHUI N9-PERAMIVIR INFLUENZA A VIRUS 6-BLADED BETA-PROPELLER HYDROLASE GLYCOSYLATION
Ref.: CHARACTERIZATION OF TWO DISTINCT NEURAMINIDASES FRO AVIAN-ORIGIN HUMAN-INFECTING H7N9 INFLUENZA VIRUSES CELL RES. V. 23 1347 2013
Members (33)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 25 families.
1 1F8E Ki = 15 uM 49A C11 H19 N3 O6 CC(=O)N[C@....
2 4MWW - G39 C14 H24 N2 O4 CCC(CC)O[C....
3 2QWG ic50 = 230 uM G28 C13 H23 N3 O5 CCN(CC)C(=....
4 1INY - EQP C10 H20 N O9 P CC(=O)N[C@....
5 1F8B Ki = 4 uM DAN C11 H17 N O8 CC(=O)N[C@....
6 1XOE ic50 = 41 nM ABX C14 H24 N2 O5 CC(C)C[C@@....
7 4MWX ic50 = 75.7 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
8 2QWC Ki = 280 uM DAN C11 H17 N O8 CC(=O)N[C@....
9 2QWJ ic50 = 0.23 uM G28 C13 H23 N3 O5 CCN(CC)C(=....
10 2QWI Ki = 2.16 uM G20 C14 H23 N5 O5 [H]/N=C(/N....
11 4MWY ic50 = 89.6 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
12 1L7G - BCZ C15 H28 N4 O4 CCC(CC)[C@....
13 1BJI ic50 = 0.002 uM DPC C20 H27 N3 O5 CCCN(CCc1c....
14 1F8D Ki = 400 uM 9AM C11 H18 N2 O7 CC(=O)N[C@....
15 2QWE Ki = 0.033 uM GNA C12 H22 N4 O7 CC(=O)N[C@....
16 4MWQ ic50 = 0.79 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
17 1NNC - ZMR C12 H20 N4 O7 CC(=O)N[C@....
18 4MX0 ic50 = 184.7 nM BCZ C15 H28 N4 O4 CCC(CC)[C@....
19 2QWB Ki = 1820 uM SIA C11 H19 N O9 CC(=O)N[C@....
20 2QWK ic50 = 0.002 uM G39 C14 H24 N2 O4 CCC(CC)O[C....
21 2QWF Ki = 2.16 uM G20 C14 H23 N5 O5 [H]/N=C(/N....
22 1MWE - SIA C11 H19 N O9 CC(=O)N[C@....
23 4MWR ic50 = 0.41 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
24 1L7F - BCZ C15 H28 N4 O4 CCC(CC)[C@....
25 1F8C Ki = 0.04 uM 4AM C11 H18 N2 O7 CC(=O)N[C@....
26 4MWU ic50 = 3.24 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
27 5JYY - 6PY C16 H27 N5 O9 [H]/N=C(N)....
28 2QWD Ki = 14 uM 4AM C11 H18 N2 O7 CC(=O)N[C@....
29 2QWH ic50 = 13 uM G39 C14 H24 N2 O4 CCC(CC)O[C....
30 4WEG - DF4 C11 H16 F N O8 CC(=O)N[C@....
31 4MWV ic50 = 0.4 nM BCZ C15 H28 N4 O4 CCC(CC)[C@....
32 4DGR ic50 = 4.4 uM 3LV C20 H30 N2 O5 CCCN(CCC)C....
33 1L7H - BCZ C15 H28 N4 O4 CCC(CC)[C@....
70% Homology Family (35)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 21 families.
1 1F8E Ki = 15 uM 49A C11 H19 N3 O6 CC(=O)N[C@....
2 4MWW - G39 C14 H24 N2 O4 CCC(CC)O[C....
3 2QWG ic50 = 230 uM G28 C13 H23 N3 O5 CCN(CC)C(=....
4 1INY - EQP C10 H20 N O9 P CC(=O)N[C@....
5 1F8B Ki = 4 uM DAN C11 H17 N O8 CC(=O)N[C@....
6 1XOE ic50 = 41 nM ABX C14 H24 N2 O5 CC(C)C[C@@....
7 4MWX ic50 = 75.7 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
8 2QWC Ki = 280 uM DAN C11 H17 N O8 CC(=O)N[C@....
9 2QWJ ic50 = 0.23 uM G28 C13 H23 N3 O5 CCN(CC)C(=....
10 2QWI Ki = 2.16 uM G20 C14 H23 N5 O5 [H]/N=C(/N....
11 4MWY ic50 = 89.6 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
12 1L7G - BCZ C15 H28 N4 O4 CCC(CC)[C@....
13 1BJI ic50 = 0.002 uM DPC C20 H27 N3 O5 CCCN(CCc1c....
14 1F8D Ki = 400 uM 9AM C11 H18 N2 O7 CC(=O)N[C@....
15 2QWE Ki = 0.033 uM GNA C12 H22 N4 O7 CC(=O)N[C@....
16 4MWQ ic50 = 0.79 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
17 1NNC - ZMR C12 H20 N4 O7 CC(=O)N[C@....
18 4MX0 ic50 = 184.7 nM BCZ C15 H28 N4 O4 CCC(CC)[C@....
19 2QWB Ki = 1820 uM SIA C11 H19 N O9 CC(=O)N[C@....
20 2QWK ic50 = 0.002 uM G39 C14 H24 N2 O4 CCC(CC)O[C....
21 2QWF Ki = 2.16 uM G20 C14 H23 N5 O5 [H]/N=C(/N....
22 1MWE - SIA C11 H19 N O9 CC(=O)N[C@....
23 4MWR ic50 = 0.41 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
24 1L7F - BCZ C15 H28 N4 O4 CCC(CC)[C@....
25 1F8C Ki = 0.04 uM 4AM C11 H18 N2 O7 CC(=O)N[C@....
26 4MWU ic50 = 3.24 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
27 5JYY - 6PY C16 H27 N5 O9 [H]/N=C(N)....
28 2QWD Ki = 14 uM 4AM C11 H18 N2 O7 CC(=O)N[C@....
29 2QWH ic50 = 13 uM G39 C14 H24 N2 O4 CCC(CC)O[C....
30 4WEG - DF4 C11 H16 F N O8 CC(=O)N[C@....
31 4MWV ic50 = 0.4 nM BCZ C15 H28 N4 O4 CCC(CC)[C@....
32 4DGR ic50 = 4.4 uM 3LV C20 H30 N2 O5 CCCN(CCC)C....
33 1L7H - BCZ C15 H28 N4 O4 CCC(CC)[C@....
34 4QN6 - LNV C13 H22 N4 O7 [H]/N=C(N)....
35 4QN7 ic50 = 0.84 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
50% Homology Family (103)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 2HTQ - ZMR C12 H20 N4 O7 CC(=O)N[C@....
2 2HT5 - NDG C8 H15 N O6 CC(=O)N[C@....
3 3O9J - RP6 C14 H21 N O8 CC(=O)N[C@....
4 2HTU - BCZ C15 H28 N4 O4 CCC(CC)[C@....
5 4D8S ic50 = 0.32 uM 0HX C13 H21 N O6 CCC(CC)O[C....
6 2HTR - DAN C11 H17 N O8 CC(=O)N[C@....
7 3O9K - ETT C21 H27 N O8 Cc1ccc(cc1....
8 4M3M - 22N C14 H24 N2 O4 CCC(CC)O[C....
9 4KS4 Ki = 72 nM 1SN C19 H30 N4 O5 CC[C@H](c1....
10 4KS1 Kd = 1.5 nM 2H8 C14 H24 N2 O4 CCC(CC)O[C....
11 4MJU - 27S C16 H23 N3 O5 S CCC(CC)O[C....
12 2HT8 - G39 C14 H24 N2 O4 CCC(CC)O[C....
13 1F8E Ki = 15 uM 49A C11 H19 N3 O6 CC(=O)N[C@....
14 4MWW - G39 C14 H24 N2 O4 CCC(CC)O[C....
15 2QWG ic50 = 230 uM G28 C13 H23 N3 O5 CCN(CC)C(=....
16 1INY - EQP C10 H20 N O9 P CC(=O)N[C@....
17 1F8B Ki = 4 uM DAN C11 H17 N O8 CC(=O)N[C@....
18 1XOE ic50 = 41 nM ABX C14 H24 N2 O5 CC(C)C[C@@....
19 4MWX ic50 = 75.7 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
20 2QWC Ki = 280 uM DAN C11 H17 N O8 CC(=O)N[C@....
21 2QWJ ic50 = 0.23 uM G28 C13 H23 N3 O5 CCN(CC)C(=....
22 2QWI Ki = 2.16 uM G20 C14 H23 N5 O5 [H]/N=C(/N....
23 4MWY ic50 = 89.6 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
24 1L7G - BCZ C15 H28 N4 O4 CCC(CC)[C@....
25 1BJI ic50 = 0.002 uM DPC C20 H27 N3 O5 CCCN(CCc1c....
26 1F8D Ki = 400 uM 9AM C11 H18 N2 O7 CC(=O)N[C@....
27 2QWE Ki = 0.033 uM GNA C12 H22 N4 O7 CC(=O)N[C@....
28 4MWQ ic50 = 0.79 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
29 1NNC - ZMR C12 H20 N4 O7 CC(=O)N[C@....
30 4MX0 ic50 = 184.7 nM BCZ C15 H28 N4 O4 CCC(CC)[C@....
31 2QWB Ki = 1820 uM SIA C11 H19 N O9 CC(=O)N[C@....
32 2QWK ic50 = 0.002 uM G39 C14 H24 N2 O4 CCC(CC)O[C....
33 2QWF Ki = 2.16 uM G20 C14 H23 N5 O5 [H]/N=C(/N....
34 1MWE - SIA C11 H19 N O9 CC(=O)N[C@....
35 4MWR ic50 = 0.41 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
36 1L7F - BCZ C15 H28 N4 O4 CCC(CC)[C@....
37 1F8C Ki = 0.04 uM 4AM C11 H18 N2 O7 CC(=O)N[C@....
38 4MWU ic50 = 3.24 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
39 5JYY - 6PY C16 H27 N5 O9 [H]/N=C(N)....
40 2QWD Ki = 14 uM 4AM C11 H18 N2 O7 CC(=O)N[C@....
41 2QWH ic50 = 13 uM G39 C14 H24 N2 O4 CCC(CC)O[C....
42 4WEG - DF4 C11 H16 F N O8 CC(=O)N[C@....
43 4MWV ic50 = 0.4 nM BCZ C15 H28 N4 O4 CCC(CC)[C@....
44 4DGR ic50 = 4.4 uM 3LV C20 H30 N2 O5 CCCN(CCC)C....
45 1L7H - BCZ C15 H28 N4 O4 CCC(CC)[C@....
46 4GZP Ki = 14.3 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
47 4GZT Ki = 17 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
48 4GZX - SIA C11 H19 N O9 CC(=O)N[C@....
49 4GZW Kd = 30 uM NAG SIA GAL n/a n/a
50 4GZQ - SIA C11 H19 N O9 CC(=O)N[C@....
51 1INF ic50 = 10 uM ST4 C10 H14 N4 O3 CC(=O)Nc1c....
52 1B9T ic50 = 8 uM RAI C14 H18 N4 O5 c1cc(c(cc1....
53 1IVB - ST1 C9 H8 N2 O6 CC(=O)Nc1c....
54 1A4Q ic50 = 3.6 uM DPC C20 H27 N3 O5 CCCN(CCc1c....
55 1NSC - SIA C11 H19 N O9 CC(=O)N[C@....
56 1A4G ic50 = 0.004 uM ZMR C12 H20 N4 O7 CC(=O)N[C@....
57 1INV - EQP C10 H20 N O9 P CC(=O)N[C@....
58 1B9S ic50 = 667 uM FDI C15 H20 N2 O4 CCC(CC)C(=....
59 3K37 ic50 = 2.8 nM BCZ C15 H28 N4 O4 CCC(CC)[C@....
60 1VCJ ic50 = 26 uM IBA C18 H27 N3 O4 CCC(CC)Nc1....
61 1B9V ic50 = 224 uM RA2 C18 H26 N2 O5 CCC(CC)Nc1....
62 1NSD - DAN C11 H17 N O8 CC(=O)N[C@....
63 4H53 - SLB C11 H19 N O9 CC(=O)N[C@....
64 4K1I - G39 C14 H24 N2 O4 CCC(CC)O[C....
65 4K1J - G39 C14 H24 N2 O4 CCC(CC)O[C....
66 4K1K - G39 C14 H24 N2 O4 CCC(CC)O[C....
67 1ING - ST5 C11 H12 N2 O5 CC(=O)Nc1c....
68 1INH - ST6 C11 H14 N3 O4 CC(=O)Nc1c....
69 1IVF - DAN C11 H17 N O8 CC(=O)N[C@....
70 1IVE - ST3 C9 H10 N2 O3 CC(=O)Nc1c....
71 1INX - EQP C10 H20 N O9 P CC(=O)N[C@....
72 1INW - AXP C10 H20 N O9 P CC(=O)N[C@....
73 2BAT - SIA C11 H19 N O9 CC(=O)N[C@....
74 1IVC - ST2 C9 H10 N2 O4 CC(=O)Nc1c....
75 1IVD - ST1 C9 H8 N2 O6 CC(=O)Nc1c....
76 4QN6 - LNV C13 H22 N4 O7 [H]/N=C(N)....
77 4WA5 ic50 = 1.29 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
78 4WA4 ic50 = 0.66 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
79 4QN5 - SIA GAL n/a n/a
80 3SAN - ZMR C12 H20 N4 O7 CC(=O)N[C@....
81 3TI8 ic50 = 0.9 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
82 2HU4 - G39 C14 H24 N2 O4 CCC(CC)O[C....
83 3TI6 ic50 = 0.54 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
84 3TI3 ic50 = 1.83 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
85 3TI5 ic50 = 1.11 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
86 3CL0 Ki = 20.8 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
87 4B7R Ki = 0.23 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
88 3TI4 ic50 = 947 nM LVO C21 H36 N4 O8 [H]/N=C(N)....
89 2HTY - NAG C8 H15 N O6 CC(=O)N[C@....
90 3CKZ Ki = 0.19 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
91 3B7E - ZMR C12 H20 N4 O7 CC(=O)N[C@....
92 4CPN - ZMR C12 H20 N4 O7 CC(=O)N[C@....
93 4CPY Ki = 491.35 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
94 4CPZ Ki = 20.85 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
95 4B7J Ki = 11.1 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
96 4QN7 ic50 = 0.84 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
97 3TIC ic50 = 1.36 nM ZMR C12 H20 N4 O7 CC(=O)N[C@....
98 3TIA ic50 = 3.12 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
99 3TIB ic50 = 129 nM LVO C21 H36 N4 O8 [H]/N=C(N)....
100 4HZZ ic50 = 8.31 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
101 4I00 - ZMR C12 H20 N4 O7 CC(=O)N[C@....
102 4HZW ic50 = 1.31 nM LNV C13 H22 N4 O7 [H]/N=C(N)....
103 4HZX ic50 = 0.5 nM G39 C14 H24 N2 O4 CCC(CC)O[C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BCZ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 BCZ 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4MWV; Ligand: BCZ; Similar sites found: 379
This union binding pocket(no: 1) in the query (biounit: 4mwv.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1YFZ IMP 0.01576 0.42026 None
2 2E1A MSE 0.02603 0.40158 None
3 3A1I UNU 0.003416 0.43514 1.03093
4 4JP3 CIT 0.00008837 0.42114 1.25523
5 1FA2 DOM 0.000002277 0.48227 1.28866
6 1KC7 PPR 0.002177 0.47356 1.28866
7 1KWK GAL 0.00804 0.40052 1.28866
8 2ZI8 SDT 0.0001651 0.42644 1.33333
9 1E4E ADP 0.003145 0.41561 1.45773
10 3FPZ AHZ 0.000002901 0.48665 1.53374
11 4G1V FAD 0.00005089 0.45871 1.54639
12 1GJW MAL 0.002332 0.44214 1.54639
13 2QS8 MET 0.0001062 0.4322 1.54639
14 1GJW GLC 0.02493 0.42098 1.54639
15 3DG6 MUC 0.005491 0.41787 1.63488
16 1T3D CYS 0.03321 0.41473 1.7301
17 1K27 MTM 0.00007431 0.42647 1.76678
18 1B55 4IP 0.001662 0.43861 1.77515
19 1EYE PMM 0.00541 0.42228 1.78571
20 1I9G SAM 0.0002767 0.40579 1.78571
21 2W8Q SIN 0.008497 0.44426 1.80412
22 4KCT PYR 0.003965 0.43727 1.80412
23 1V5F FAD 0.0009725 0.43596 1.80412
24 1V5F TPP 0.0009725 0.43596 1.80412
25 2Q8H TF4 0.04209 0.42067 1.80412
26 1E2S CSN 0.005786 0.41695 1.80412
27 4KCT FDP 0.008596 0.41401 1.80412
28 2IZ1 ATR 0.02987 0.41197 1.80412
29 1WDA BAG 0.01848 0.40811 1.80412
30 1QW9 KHP 0.001823 0.40376 1.80412
31 9LDT OXM 0.01462 0.45307 1.80723
32 4NAO AKG 0.04513 0.40802 1.84049
33 1LTH FBP 0.00004008 0.54939 1.88088
34 1LTH OXM 0.00002639 0.52424 1.88088
35 2AMT GPP 0.01394 0.40337 1.88679
36 1GSA ADP 0.00001897 0.43902 1.89873
37 1GSA GSH 0.00002951 0.4267 1.89873
38 1JCM 137 0.0003148 0.41803 1.9305
39 1ML4 PAL 0.002031 0.40689 1.94805
40 2WL9 MBD 0.0001137 0.44637 1.96721
41 3CEV ARG 0.01388 0.41355 2.00669
42 2GN2 C5P 0.00001572 0.50652 2.04678
43 1Z6K OAA 0.002115 0.44144 2.04778
44 1OMZ UD2 0.00001032 0.44119 2.04778
45 2NZ2 ASP 0.0003051 0.49236 2.06186
46 1ONX ASP 0.00002894 0.4572 2.06186
47 4A1O AMZ 0.002986 0.41963 2.06186
48 1YBQ BDH 0.0000824 0.41581 2.06186
49 2PP3 LGT 0.00005769 0.41391 2.06186
50 3RHZ UDP 0.006438 0.4041 2.0649
51 2V5K OXM 0.002722 0.43688 2.09059
52 1P72 THM 0.01563 0.4157 2.09581
53 1G7V PAI 0.00006854 0.40531 2.11268
54 3VGL BGC 0.0008595 0.40493 2.18069
55 1OTH PAO 0.00005904 0.40368 2.18069
56 1AUX AGS 0.006317 0.40789 2.2508
57 4A8H PUW 0.000205 0.41872 2.25352
58 1S8F GDP 0.001698 0.40175 2.25989
59 3L6R MLI 0.01605 0.43053 2.31214
60 4WBD ADP 0.005199 0.45484 2.31959
61 4IVG ANP 0.000009754 0.44907 2.31959
62 2F2U M77 0.00376 0.43338 2.31959
63 1V8K ANP 0.00007668 0.42943 2.31959
64 2ADD SUC 0.006406 0.42672 2.31959
65 4WBD CIT 0.03448 0.41936 2.31959
66 2WVZ KIF 0.009336 0.40524 2.31959
67 1K6M AGS 0.004195 0.40416 2.31959
68 4HPP GLU 0.0002514 0.40298 2.31959
69 1DXY COI 0.03926 0.42232 2.4024
70 1V6A TRE 0.01455 0.42188 2.40964
71 1LYX PGA 0.01354 0.40216 2.41935
72 2BGM NAJ 0.0004635 0.40907 2.51799
73 3ZGE ASP 0.006285 0.45758 2.57732
74 1ZFJ IMP 0.00002388 0.43162 2.57732
75 1P9B HDA 0.01027 0.42892 2.57732
76 1P9B GDP 0.001841 0.4282 2.57732
77 3BK2 U5P 0.004015 0.42761 2.57732
78 2Z5Y HRM 0.0001947 0.42429 2.57732
79 2VJJ RAM GLC GAL NAG NAG GLC 0.0001076 0.42039 2.57732
80 1KBI FMN 0.00108 0.40791 2.57732
81 1KBI PYR 0.00108 0.40791 2.57732
82 4JRB PGT 0.01223 0.4077 2.57732
83 1J2Z SOG 0.004046 0.41714 2.59259
84 1RYI GOA 0.005086 0.48793 2.6178
85 2WIC GNP 0.002939 0.40156 2.62172
86 3ZF8 GDP 0.007667 0.42029 2.62295
87 3K3G MMU 0.000435 0.48888 2.64706
88 3SHR CMP 0.008281 0.41888 2.67559
89 3PMA SCR 0.01483 0.41674 2.7027
90 1M1B SPV 0.02836 0.40835 2.71186
91 2BLE 5GP 0.00005661 0.43617 2.7248
92 1ECM TSA 0.01614 0.41069 2.75229
93 3QDY CBS 0.003335 0.46439 2.7972
94 3QDW NDG 0.007128 0.44805 2.7972
95 3QDT A2G GAL 0.0157 0.4371 2.7972
96 3QDY A2G GAL 0.02196 0.42955 2.7972
97 4N02 FNR 0.00002004 0.44276 2.80112
98 4O8A 2OP 0.02467 0.43325 2.83505
99 4UAL 3FV 0.00266 0.42214 2.83505
100 4QDC ASD 0.0003618 0.42111 2.83505
101 1TV5 A26 0.001169 0.42005 2.83505
102 3CXO 3LR 0.00001834 0.40941 2.83505
103 4A38 BZS 0.01591 0.40854 2.83505
104 1TV5 ORO 0.007776 0.40623 2.83505
105 4QDF 30Q 0.001689 0.40036 2.83505
106 3VOZ 04A 0.0002104 0.46388 2.85714
107 4Q3S X7A 0.0001016 0.43822 2.85714
108 4Q3R XA2 0.0004638 0.42282 2.85714
109 1C3V PDC 0.01775 0.41786 2.85714
110 1EDO NAP 0.00009282 0.43676 2.86885
111 4NVP 7CH 0.000003249 0.453 2.87081
112 3ZPG 5GP 0.02676 0.43135 2.87958
113 3NNF AKG 0.01778 0.42285 2.90698
114 1JA9 NDP 0.00011 0.43465 2.91971
115 1JA9 PYQ 0.000006219 0.42037 2.91971
116 4G28 0W8 0.01721 0.40946 2.94118
117 4HE2 AMP 0.00001676 0.44842 2.95858
118 3I51 45C 0.01227 0.40764 2.96296
119 2VQ5 HBA 0.0269 0.41933 2.98507
120 2Y6P CTP 0.01467 0.40834 2.99145
121 1I0Z OXM 0.01993 0.43825 3.003
122 4IU0 ABH 0.001522 0.41611 3.0303
123 1XX4 BAM 0.00301 0.45067 3.06513
124 3VCA PRO 0.0003352 0.49403 3.09278
125 2BO4 FLC 0.002846 0.4678 3.09278
126 3IHB GLU 0.0121 0.43664 3.09278
127 4LIT AKG 0.01132 0.42695 3.09278
128 1VCO GLN 0.0006309 0.41523 3.09278
129 4LHM AZZ 0.02086 0.41459 3.09278
130 4HA6 PXM 0.03005 0.40718 3.09278
131 3IHB TRS 0.01997 0.40617 3.09278
132 3UER TUR 0.01351 0.40592 3.09278
133 3UER BTU 0.01351 0.40592 3.09278
134 1T26 NAI 0.00002624 0.46678 3.10559
135 1T26 GBD 0.00002624 0.46678 3.10559
136 1R6W 164 0.005846 0.41287 3.10559
137 2R5T ANP 0.001324 0.4218 3.21716
138 1V7R CIT 0.04321 0.42656 3.22581
139 3PNA CMP 0.01281 0.41507 3.24675
140 3MAG 3MA 0.03124 0.43454 3.25733
141 3F81 STT 0.01051 0.45317 3.27869
142 4P87 4NP 0.00009283 0.44133 3.35052
143 2NCD ADP 0.005743 0.44062 3.35052
144 3NKS ACJ 0.005627 0.41352 3.35052
145 1WTC ACP 0.04821 0.40657 3.40557
146 4IMG NGF 0.004051 0.40804 3.41297
147 2QCX PF1 0.01196 0.42584 3.42205
148 2X61 NGA GAL SIA 0.00001639 0.44924 3.48837
149 2X61 CH 0.000004432 0.44526 3.48837
150 4LFL TG6 0.008529 0.41833 3.48837
151 1IZC PYR 0.0001733 0.44851 3.53982
152 3A2Y TS5 0.003778 0.41637 3.5533
153 3U1T MLI 0.0002661 0.51869 3.55987
154 1SQ5 PAU 0.01763 0.41334 3.57143
155 4JWX 1N4 0.02255 0.40851 3.57143
156 1Q3Q ANP 0.000000729 0.48665 3.60825
157 1PX8 XYP 0.01246 0.42502 3.60825
158 3PLN U5P 0.01092 0.42272 3.60825
159 1Z45 GAL 0.01409 0.41774 3.60825
160 1Z45 UPG 0.007882 0.40084 3.60825
161 1AL8 FMN 0.0000009826 0.41773 3.62117
162 2DWU DGL 0.01488 0.41223 3.62319
163 1PEA ACM 0.03744 0.41749 3.63636
164 3H86 AP5 0.00005938 0.43041 3.64583
165 3DGB MUC 0.007856 0.41562 3.66492
166 4KGM ATP 0.01358 0.40582 3.67347
167 3PHQ KDO 0.02091 0.46065 3.68664
168 3EW2 BTN 0.0253 0.40212 3.7037
169 1O9U ADZ 0.01926 0.43905 3.71429
170 2AEB ABH 0.0001137 0.40014 3.72671
171 4GQB 0XU 0.00002726 0.43912 3.77907
172 3DX5 DHB 0.004984 0.42821 3.84615
173 4N69 SER 0.0228 0.41764 3.84615
174 2QV7 ADP 0.0004556 0.45597 3.85757
175 1HV9 UD1 0.00007506 0.42635 3.86598
176 1E5F PLP 0.003509 0.4215 3.86598
177 4RJK PYR 0.03519 0.4189 3.86598
178 2QF7 COA 0.007003 0.41364 3.86598
179 1QH9 LAC 0.02741 0.41378 3.87931
180 1FX8 BOG 0.00002455 0.4992 3.91459
181 2FGQ MLT 0.0007682 0.48816 3.91566
182 2TOH HBI 0.00009258 0.44929 4.08163
183 2WGC SIA GAL BGC 0.01583 0.45964 4.09357
184 3T2W BTN 0.006533 0.42324 4.09836
185 3EM1 TYD 0.0003894 0.43068 4.10959
186 4LO6 SIA GAL 0.0004162 0.51348 4.12371
187 2ZJ5 ADP 0.01813 0.41743 4.12371
188 2YP9 SIA CMO 0.005108 0.41325 4.12371
189 3K5X P8D 0.01425 0.40888 4.12371
190 3OIG NAD 0.0001229 0.42678 4.13534
191 3OIG IMJ 0.00001127 0.42244 4.13534
192 1RZM PEP 0.004135 0.44166 4.14201
193 2GJ3 FAD 0.00006701 0.44531 4.16667
194 2JE7 XMM 0.0002226 0.42942 4.1841
195 3KMT SAH 0.002525 0.43135 4.20168
196 1XMV ADP 0.000341 0.4083 4.21348
197 2P41 G1G 0.02162 0.40512 4.2623
198 2GJN NIS 0.001446 0.40099 4.26829
199 3LTW HLZ 0.034 0.40924 4.28571
200 1NML CIT 0.01785 0.41309 4.29448
201 2XI7 XI7 0.0264 0.44659 4.34783
202 4GLJ RHB 0.0003996 0.40589 4.3771
203 1I2B NAD 0.001501 0.4238 4.38144
204 1I2B UPG 0.001501 0.4238 4.38144
205 1I2B USQ 0.001501 0.4238 4.38144
206 4M51 BEZ 0.03412 0.4196 4.38144
207 1QR0 COA 0.00225 0.4428 4.38596
208 1AUA BOG 0.00844 0.42775 4.39189
209 1YHM AHD 0.0145 0.42196 4.41989
210 3O03 NAP 0.0008337 0.40201 4.46735
211 1N9L FMN 0.008249 0.40011 4.58716
212 1QO0 BMD 0.03865 0.40653 4.59184
213 1UF5 CDT 0.009808 0.41576 4.62046
214 1W7J ADP BEF 0.005881 0.40907 4.63576
215 3B9Z CO2 0.0002814 0.50899 4.63918
216 3L24 GOA 0.001776 0.49442 4.63918
217 4AF0 MOA 0.00005768 0.45603 4.63918
218 4A3R CIT 0.000002736 0.45498 4.63918
219 4AF0 IMP 0.000009716 0.40349 4.63918
220 4WNB 4BN 0.006023 0.40868 4.65116
221 3CBG 4FE 0.002225 0.49866 4.74138
222 4MOB ADP 0.0002049 0.46685 4.81928
223 2EB5 OXL 0.02129 0.41908 4.86891
224 3IB9 BTN 0.006172 0.45448 4.89691
225 3HZL 6PC 0.01612 0.4432 4.89691
226 1N6B DMZ 0.00001572 0.42827 4.89691
227 3PIJ FRU 0.01712 0.40519 4.89691
228 2Q37 3AL 0.003035 0.45344 4.97238
229 1UW1 ADP 0.01135 0.42689 5
230 3SCH TB6 0.004685 0.45064 5.05051
231 1ZZ7 S0H 0.02469 0.40673 5.05051
232 3E5H GNP 0.001352 0.41111 5.05618
233 1A5V Y3 0.009704 0.43006 5.06329
234 1JN2 SFP 0.0118 0.40456 5.06329
235 2ZO9 MLI 0.002693 0.43708 5.10949
236 3OH3 UAD 0.007217 0.41668 5.15464
237 4TMK T5A 0.0004273 0.43688 5.16432
238 3W54 RNB 0.01209 0.40413 5.16717
239 2FOI JPA 0.001354 0.4521 5.20446
240 4PTZ FMN 0.002224 0.42509 5.2356
241 1H8G CHT 0.01318 0.46431 5.26316
242 5A2J ALA PRO ASP THR ARG PRO 0.01792 0.43733 5.32787
243 1ULE GLA GAL NAG 0.02134 0.43019 5.33333
244 2JBH 5GP 0.007632 0.42489 5.33333
245 1UAY ADN 0.01505 0.40031 5.3719
246 1Y7P RIP 0.0244 0.42717 5.38117
247 4OYA 1VE 0.001288 0.41782 5.41237
248 3NOJ PYR 0.02184 0.41136 5.46218
249 1MVQ MMA 0.0004184 0.40823 5.50847
250 2YLD CMO 0.02852 0.41295 5.51181
251 1B4P GPS 0.00458 0.40957 5.52995
252 3M0J OAF 0.000735 0.40119 5.53746
253 2H6B 3C4 0.0006321 0.40366 5.6
254 3EJ0 11X 0.003896 0.44557 5.61225
255 4B9E FAH 0.004795 0.45658 5.64784
256 4N7C AEF 0.01515 0.43177 5.68182
257 3Q3C NAD 0.0005281 0.40405 5.68562
258 2HW1 FRU 0.006829 0.43713 5.7047
259 1WKL ATP 0.0007857 0.43786 5.83942
260 1WKL ADP 0.001315 0.4296 5.83942
261 2GGH NLQ 0.00002972 0.42754 5.86667
262 3WUD GLC GAL 0.0433 0.41419 5.88235
263 1Z44 FMN 0.00556 0.41765 5.91716
264 1Z41 FMN 0.01234 0.40021 5.91716
265 1C7S CBS 0.01631 0.40253 5.92783
266 3S9K CIT 0.00001179 0.6603 5.9322
267 4QCK ASD 0.000164 0.4373 5.95855
268 4Q3F TLA 0.00141 0.47557 5.98291
269 1PTR PRB 0.0176 0.42853 6
270 5DRN 5CT 0.01475 0.44894 6.01852
271 1LDM OXM 0.00005237 0.51168 6.07903
272 1G8S MET 0.01276 0.42979 6.08696
273 2IMP NAI 0.0002184 0.4317 6.18557
274 1D3V ABH 0.00003427 0.45909 6.19195
275 43CA NPO 0.0189 0.45816 6.19469
276 1TH8 ADP 0.01562 0.40719 6.2069
277 3GM5 CIT 0.01463 0.42693 6.28931
278 3KJQ B94 0.01311 0.40645 6.31579
279 1JQN DCO 0.000008484 0.44922 6.4433
280 2IYG FMN 0.01335 0.40613 6.45161
281 1YRO UDP 0.01901 0.40461 6.50407
282 1SS4 GSH 0.006925 0.48773 6.53595
283 1C1L GAL BGC 0.01104 0.43861 6.56934
284 1BTN I3P 0.0392 0.4359 6.60377
285 4LKK SIA GAL 0.0003528 0.4507 6.6879
286 1O7N IND 0.001772 0.41384 6.70103
287 1Y75 NAG 0.00349 0.43968 6.77966
288 3UXL CFI 0.000006707 0.42446 6.78851
289 2EJU SAH 0.005318 0.40717 6.87831
290 4F8L GAL 0.006313 0.48299 6.89655
291 1XE7 GUN 0.006337 0.46492 6.89655
292 1FWE HAE 0.005178 0.43223 7
293 2JAR UMP 0.004475 0.40994 7
294 1GPJ CIT 0.01668 0.42419 7.2165
295 3NJQ NJQ 0.00006618 0.44593 7.25389
296 3TFC PEP 0.001048 0.46837 7.27273
297 3I8T LBT 0.00004456 0.52976 7.31707
298 1H16 PYR 0.02919 0.42313 7.47423
299 2Q1A 2KT 0.03549 0.40834 7.50853
300 4B16 NAG 0.03688 0.43046 7.5188
301 3UEC ALA ARG TPO LYS 0.04139 0.40992 7.53425
302 1NXJ GLV 0.0005092 0.47601 7.65027
303 1NXJ TLA 0.0007171 0.44598 7.65027
304 1GXU 2HP 0.001393 0.41743 7.69231
305 1B5E DCM 0.0162 0.41061 7.72358
306 3CQ5 PMP 0.02637 0.40133 7.85908
307 1Y1A GSH 0.01213 0.4713 8.19672
308 4AP9 1PS 0.0009028 0.43155 8.45771
309 4AIG FLX 0.01421 0.40893 8.45771
310 2HFK E4H 0.009545 0.42535 8.46395
311 4FGC PQ0 0.01821 0.41735 8.48485
312 2YDW WSH 0.007659 0.42031 8.49673
313 4LCQ URQ 0.00003505 0.44664 8.50515
314 2FH5 GTP 0.000008025 0.41693 8.64865
315 1HFA PIO 0.001998 0.45207 8.65052
316 3WN0 FUB 0.002474 0.40843 8.76289
317 4JEJ 1GP 0.008731 0.41373 9.01639
318 2YIV YIV 0.0381 0.4171 9.02062
319 1SJW NGV 0.00003884 0.41828 9.02778
320 2Q8M AMP 0.002949 0.43311 9.03614
321 2OWZ CIT 0.02979 0.41203 9.03614
322 1A5Z OXM 0.00002557 0.5802 9.09091
323 1A5Z FBP 0.0005095 0.4405 9.09091
324 1WHT BZS 0.02842 0.41302 9.15033
325 1AX2 NDG GAL 0.02175 0.40922 9.20502
326 2NLI LAC 0.000572 0.40128 9.23913
327 2NLI FMN 0.000572 0.40128 9.23913
328 1NU4 MLA 0.001507 0.45554 9.27835
329 4I9A NCN 0.0004501 0.41336 9.375
330 4KCF AKM 0.0001028 0.42143 9.53608
331 2Y0I AKG 0.03016 0.4071 9.65909
332 3P3N AKG 0.01 0.43486 9.74212
333 4B7E OGA 0.009901 0.42965 9.74212
334 2WA4 069 0.01377 0.40557 9.74212
335 1R5A GTS 0.01347 0.41412 10.0917
336 2ZE3 AKG 0.03547 0.40379 10.1818
337 2BZ1 TAU 0.01543 0.4603 10.2041
338 1NVU GTP 0.00001284 0.45014 10.241
339 1UGX GAL MGC 0.0002549 0.42078 10.5263
340 1OGD RIP 0.01785 0.4131 10.687
341 3ZZS TRP 0.00003167 0.42681 10.7692
342 2F59 INI 0.00609 0.40499 10.828
343 1A8S PPI 0.02035 0.4004 10.989
344 4LBP 1WG 0.0005139 0.41164 11
345 4AF5 CIT 0.02341 0.41709 11.0526
346 1CKM GTP 0.01056 0.41875 11.2121
347 1JOT GAL A2G 0.0002709 0.48159 11.2782
348 3CF6 SP1 0.00918 0.40523 11.3772
349 4M7F BM3 0.0003298 0.49084 11.5044
350 1JGS SAL 0.0008947 0.53241 11.5942
351 4IEN GDP 0.001068 0.40653 11.6564
352 4NTX AMR 0.001272 0.46769 11.6667
353 4O8O AHR 0.001428 0.43383 11.7188
354 4BPM GSH 0.001699 0.40475 11.7978
355 1FNZ A2G 0.0001168 0.4544 11.8143
356 2GWD GLU 0.006104 0.42911 11.8557
357 3R51 MMA 0.003162 0.48105 12.5
358 2HMT NAI 0.000009195 0.44744 12.5
359 4PNO U5P 0.001113 0.44556 12.5
360 2PFC PLM 0.006614 0.41869 12.5683
361 2HVK TBA 0.003837 0.45478 12.7854
362 2B7N NTM 0.0137 0.4231 12.8205
363 1RYD GLC 0.007379 0.44119 12.9199
364 2FR6 CTN 0.001478 0.42773 13.0137
365 2O66 FLC 0.02157 0.41392 13.3333
366 2YD6 FLC 0.0006881 0.54047 13.4021
367 3CH5 GDP 0.0001027 0.41934 13.4615
368 4HZO COA 0.007031 0.43131 13.522
369 1Y9Q MED 0.03051 0.41152 14.0625
370 2X2T GAL NGA 0.002817 0.48373 14.3791
371 3WCS MAN NAG GAL 0.01975 0.40285 14.5669
372 3WCS MAN NAG 0.03134 0.40202 14.5669
373 3MB5 SAM 0.000005247 0.40418 14.902
374 4DN8 BMA 0.004338 0.45224 19.2308
375 2CCV A2G 0.001162 0.41004 20.7921
376 3KPE TM3 0.001432 0.47525 21.5686
377 4CCN OGA 0.02572 0.41511 22.8571
378 4CCO OGA 0.0239 0.40737 25
379 1JAC AMG 0.004422 0.48206 30
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