-->
Receptor
PDB id Resolution Class Description Source Keywords
1JIF 1.6 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF BLEOMYCIN-BINDING PROTEIN FROM BLEOMYCIN-PRODUCING STREPTOMYCES VERTICILLUS COMPLEXED W ITH COPPER(II)-BLEOMYCIN STREPTOMYCES VERTICILLUS PROTEIN-LIGAND COMPLEX PROTEIN BINDING
Ref.: THE 1.6-A CRYSTAL STRUCTURE OF THE COPPER(II)-BOUND BLEOMYCIN COMPLEXED WITH THE BLEOMYCIN-BINDING PROTEIN FROM BLEOMYCIN-PRODUCING STREPTOMYCES VERTICILLUS. J.BIOL.CHEM. V. 277 2311 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:502;
B:501;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
CU BLM A:404;
B:403;
Valid;
Valid;
none;
none;
Kd ~ 350 nM n/a n/a n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1JIF 1.6 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF BLEOMYCIN-BINDING PROTEIN FROM BLEOMYCIN-PRODUCING STREPTOMYCES VERTICILLUS COMPLEXED W ITH COPPER(II)-BLEOMYCIN STREPTOMYCES VERTICILLUS PROTEIN-LIGAND COMPLEX PROTEIN BINDING
Ref.: THE 1.6-A CRYSTAL STRUCTURE OF THE COPPER(II)-BOUND BLEOMYCIN COMPLEXED WITH THE BLEOMYCIN-BINDING PROTEIN FROM BLEOMYCIN-PRODUCING STREPTOMYCES VERTICILLUS. J.BIOL.CHEM. V. 277 2311 2002
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1JIE - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
2 1JIF Kd ~ 350 nM CU BLM n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1JIE - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
2 1JIF Kd ~ 350 nM CU BLM n/a n/a
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1JIE - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
2 1JIF Kd ~ 350 nM CU BLM n/a n/a
3 2ZHP Ka = 47100000 M^-1 BY6 CU n/a n/a
4 1XRK - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
5 5CJ3 - 52G C55 H85 N19 O21 S2 [H]/N=C(CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CU BLM; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1JIF; Ligand: CU BLM; Similar sites found with APoc: 83
This union binding pocket(no: 1) in the query (biounit: 1jif.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
1 5EZU MYR None
2 4RDL FUC GAL NDG FUC None
3 2BVE PH5 None
4 5ACM MBT None
5 5H20 GLC None
6 5N1X 8HH None
7 5IXB LGA None
8 6GG9 FMN None
9 3W68 PBU None
10 4CNO 9PY 1.63934
11 3TW1 AHN 1.63934
12 6C5F 7L9 1.7094
13 4G0P U5P 2.45902
14 4WOE ADP 2.45902
15 3V8S 0HD 3.27869
16 2GTF P1R 3.27869
17 1ELI PYC 4.09836
18 1H4H XYP XYS XYP 4.09836
19 4OPC FDA 4.09836
20 4OPC PGT 4.09836
21 3JU6 ANP 4.09836
22 4BG4 ADP 4.09836
23 2AG4 OLA 4.09836
24 2AG4 LP3 4.09836
25 3RGA LSB 4.09836
26 4IAW LIZ 4.09836
27 4U8P UDP 4.91803
28 3NNT DQA 4.91803
29 1Y7P RIP 4.91803
30 3HAV ATP 4.91803
31 4GLW NMN 4.91803
32 4L9I 8PR 4.91803
33 6D61 4AA 4.91803
34 1N9L FMN 5.50459
35 2QL9 CIT 5.7377
36 3VV1 GAL FUC 5.7377
37 1F9V ADP 5.7377
38 3M3E GAL A2G NPO 5.7377
39 2ZL7 FUC GAL NGA 5.7377
40 4K55 H6P 5.7377
41 3ZGJ RMN 5.7377
42 2Z6D FMN 5.7377
43 4OEE GNX IDY 5.7377
44 2W5P CL8 5.7377
45 1SDW IYT 6.55738
46 4P25 FUC GAL NAG FUC 6.55738
47 3G08 FEE 6.55738
48 2VGD XYP XYP 6.55738
49 3JQ3 ADP 6.55738
50 6GNO XDI 7.37705
51 6FA4 D1W 7.37705
52 5DYO FLU 7.37705
53 4WUJ FMN 7.37705
54 4HK8 XYP XYP XYP XYP XYP XYP 7.37705
55 4LIK CIT 8.19672
56 6C0B MLI 8.19672
57 5ZKC 3C0 8.19672
58 5XQW 8EU 8.19672
59 4B9E FAH 8.19672
60 4GCZ FMN 8.19672
61 5TCI MLI 8.19672
62 2QPU QPS 9.01639
63 2QPU QPU 9.01639
64 4XJ6 GH3 9.83607
65 1S5O 152 11.4754
66 3CBC DBS 12.1212
67 2XG5 EC5 12.2951
68 2XG5 EC2 12.2951
69 5YJS SAL 12.2951
70 4RD0 GDP 13.1148
71 3PUR 2HG 13.9344
72 2PNC CLU 13.9344
73 2P7Q GG6 13.9344
74 6E1Q CFA 14.7541
75 3VPD BUA 14.7541
76 5TZO 7V7 14.7541
77 5W75 SUC 15.5738
78 5KEW 6SB 17.0213
79 5C2N NAG 18.75
80 6DZN AE3 22.9508
81 2G30 ALA ALA PHE 28.6885
82 3O2K DST 31.9672
83 1EWJ BLM 39.3443
Pocket No.: 2; Query (leader) PDB : 1JIF; Ligand: CU BLM; Similar sites found with APoc: 4
This union binding pocket(no: 2) in the query (biounit: 1jif.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 3KPE TM3 None
2 1I06 TZL 2.45902
3 5OCG 9R5 7.37705
4 3OUM TOF 28.6885
APoc FAQ
Feedback