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Receptor
PDB id Resolution Class Description Source Keywords
1IM8 2.2 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF YECO FROM HAEMOPHILUS INFLUENZAE (HI031 METHYLTRANSFERASE WITH A BOUND S-ADENOSYLHOMOCYSTEINE HAEMOPHILUS INFLUENZAE RD METHYLTRANSFERASE ADENOSYLHOMOCYSTEINE STRUCTURAL GENOMICSHYPOTHETICAL PROTEIN STRUCTURE 2 FUNCTION PROJECT S2F TR
Ref.: CRYSTAL STRUCTURE OF YECO FROM HAEMOPHILUS INFLUENZ (HI0319) REVEALS A METHYLTRANSFERASE FOLD AND A BOU S-ADENOSYLHOMOCYSTEINE. PROTEINS V. 45 397 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:300;
B:301;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
SAI A:302;
B:303;
Valid;
Valid;
none;
none;
submit data
431.306 C14 H20 N6 O5 Se c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1IM8 2.2 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF YECO FROM HAEMOPHILUS INFLUENZAE (HI031 METHYLTRANSFERASE WITH A BOUND S-ADENOSYLHOMOCYSTEINE HAEMOPHILUS INFLUENZAE RD METHYLTRANSFERASE ADENOSYLHOMOCYSTEINE STRUCTURAL GENOMICSHYPOTHETICAL PROTEIN STRUCTURE 2 FUNCTION PROJECT S2F TR
Ref.: CRYSTAL STRUCTURE OF YECO FROM HAEMOPHILUS INFLUENZ (HI0319) REVEALS A METHYLTRANSFERASE FOLD AND A BOU S-ADENOSYLHOMOCYSTEINE. PROTEINS V. 45 397 2001
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 1IM8 - SAI C14 H20 N6 O5 Se c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 4IWN - GEK C16 H22 N6 O7 S c1nc(c2c(n....
2 1IM8 - SAI C14 H20 N6 O5 Se c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 4IWN - GEK C16 H22 N6 O7 S c1nc(c2c(n....
2 1IM8 - SAI C14 H20 N6 O5 Se c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAI; Similar ligands found: 205
No: Ligand ECFP6 Tc MDL keys Tc
1 SAI 1 1
2 SFG 0.654762 0.940298
3 SA8 0.62069 0.902778
4 SAH 0.613636 0.955882
5 EEM 0.6 0.930556
6 5X8 0.597701 0.926471
7 S7M 0.586957 0.878378
8 RAB 0.573333 0.828571
9 XYA 0.573333 0.828571
10 ADN 0.573333 0.828571
11 SAM 0.571429 0.878378
12 5CD 0.571429 0.84058
13 0UM 0.5625 0.864865
14 5N5 0.558442 0.828571
15 62X 0.556701 0.844156
16 A4D 0.551282 0.828571
17 K15 0.55102 0.866667
18 DTA 0.54321 0.819444
19 SMM 0.536842 0.844156
20 KB1 0.534653 0.890411
21 EP4 0.530864 0.808219
22 M2T 0.52439 0.786667
23 6RE 0.523256 0.813333
24 MTA 0.518072 0.830986
25 KH3 0.514019 0.855263
26 AMP 0.511628 0.753247
27 LMS 0.511628 0.666667
28 A 0.511628 0.753247
29 ABM 0.511364 0.734177
30 3DH 0.505882 0.830986
31 GJV 0.505618 0.802632
32 SON 0.505495 0.794872
33 SSA 0.505155 0.685393
34 SRP 0.505155 0.794872
35 AMO 0.5 0.794872
36 CA0 0.5 0.759494
37 VMS 0.5 0.655556
38 GSU 0.5 0.724138
39 5AL 0.5 0.769231
40 54H 0.5 0.655556
41 DSZ 0.5 0.704545
42 53H 0.494949 0.648352
43 5CA 0.494949 0.685393
44 A5A 0.494845 0.670455
45 50T 0.494624 0.746835
46 J7C 0.494382 0.824324
47 A2D 0.494382 0.734177
48 ZAS 0.494253 0.797297
49 GEK 0.49 0.915493
50 A3S 0.48913 0.871429
51 A7D 0.48913 0.885714
52 AN2 0.48913 0.725
53 S4M 0.488889 0.797468
54 SRA 0.488636 0.716049
55 KAA 0.485437 0.7
56 LAD 0.485437 0.8
57 NSS 0.485149 0.685393
58 LSS 0.485149 0.67033
59 ADX 0.483871 0.666667
60 M33 0.483871 0.725
61 A12 0.483516 0.75
62 AP2 0.483516 0.75
63 BA3 0.483516 0.734177
64 DSH 0.483146 0.875
65 AOC 0.483146 0.830986
66 Y3J 0.481481 0.757143
67 ME8 0.480769 0.780488
68 SXZ 0.480769 0.878378
69 AHX 0.480392 0.743902
70 NVA LMS 0.480392 0.681319
71 TSB 0.48 0.662921
72 G5A 0.479167 0.685393
73 AP5 0.478261 0.734177
74 5AS 0.478261 0.630435
75 ADP 0.478261 0.734177
76 B4P 0.478261 0.734177
77 F0P 0.477876 0.902778
78 A3N 0.477778 0.819444
79 8QN 0.475248 0.769231
80 GAP 0.474227 0.759494
81 0XU 0.473684 0.884058
82 AT4 0.473118 0.707317
83 52H 0.47 0.648352
84 5AD 0.468354 0.779412
85 AU1 0.468085 0.716049
86 MAO 0.467391 0.7875
87 FA5 0.46729 0.794872
88 YAP 0.46729 0.78481
89 TXA 0.466667 0.75
90 NB8 0.466667 0.765432
91 A3G 0.466667 0.859155
92 NEC 0.466667 0.777778
93 3AM 0.465909 0.717949
94 DAL AMP 0.465347 0.769231
95 ACP 0.463158 0.7375
96 HEJ 0.463158 0.734177
97 A3T 0.463158 0.830986
98 ATP 0.463158 0.734177
99 XAH 0.462963 0.759036
100 7D7 0.4625 0.774648
101 LEU LMS 0.461538 0.663043
102 OOB 0.460784 0.769231
103 9ZA 0.460784 0.731707
104 9ZD 0.460784 0.731707
105 5FA 0.458333 0.734177
106 PRX 0.458333 0.7375
107 AR6 0.458333 0.75641
108 AQP 0.458333 0.734177
109 APR 0.458333 0.75641
110 APC 0.458333 0.75
111 F2R 0.457627 0.741176
112 WAQ 0.457143 0.797468
113 4AD 0.456311 0.78481
114 PAJ 0.456311 0.714286
115 AAT 0.454545 0.826667
116 SAP 0.453608 0.698795
117 AGS 0.453608 0.698795
118 AD9 0.453608 0.7375
119 A5D 0.453608 0.819444
120 ADP PO3 0.453608 0.753247
121 RBY 0.453608 0.772152
122 ADV 0.453608 0.772152
123 9K8 0.45283 0.645161
124 PTJ 0.45283 0.722892
125 MHZ 0.452632 0.7875
126 YLC 0.452174 0.780488
127 00A 0.451923 0.731707
128 YLP 0.451327 0.761905
129 8X1 0.45098 0.681319
130 7MD 0.45045 0.759036
131 YSA 0.449541 0.685393
132 VRT 0.44898 0.849315
133 S8M 0.446602 0.863014
134 ACQ 0.444444 0.7375
135 TAT 0.444444 0.707317
136 ANP 0.444444 0.716049
137 T99 0.444444 0.707317
138 TT8 0.441176 0.928571
139 YLA 0.440678 0.761905
140 8PZ 0.440367 0.685393
141 YLB 0.439655 0.761905
142 48N 0.438596 0.743902
143 2AM 0.438202 0.708861
144 DLL 0.438095 0.769231
145 ARG AMP 0.4375 0.75
146 D3Y 0.436893 0.847222
147 A22 0.436893 0.725
148 MAP 0.436893 0.719512
149 A3P 0.43617 0.730769
150 ATF 0.435644 0.707317
151 ADP ALF 0.435644 0.719512
152 ALF ADP 0.435644 0.719512
153 80F 0.434426 0.72093
154 A6D 0.433962 0.728395
155 9X8 0.433962 0.719512
156 3UK 0.433962 0.759494
157 OAD 0.433962 0.759494
158 2VA 0.43299 0.808219
159 VO4 ADP 0.431373 0.746835
160 ADP VO4 0.431373 0.746835
161 6YZ 0.431373 0.7375
162 9SN 0.431193 0.722892
163 TYM 0.431034 0.794872
164 P5A 0.429907 0.692308
165 PR8 0.429907 0.790123
166 B5V 0.429907 0.75
167 7C5 0.428571 0.779221
168 A3R 0.428571 0.753086
169 A1R 0.428571 0.753086
170 B5Y 0.427273 0.740741
171 7D5 0.426966 0.7
172 FYA 0.425926 0.769231
173 1ZZ 0.425926 0.738095
174 3OD 0.425926 0.759494
175 AYB 0.425 0.752941
176 NVA 2AD 0.424242 0.837838
177 MYR AMP 0.422018 0.738095
178 IOT 0.420168 0.752941
179 SO8 0.42 0.797297
180 TYR AMP 0.419643 0.78481
181 25A 0.419048 0.734177
182 5SV 0.419048 0.722892
183 WSA 0.418803 0.693182
184 3NZ 0.416667 0.813333
185 ADQ 0.415094 0.7375
186 B5M 0.414414 0.740741
187 JB6 0.412844 0.731707
188 BIS 0.412844 0.710843
189 GA7 0.412281 0.728395
190 PPS 0.411765 0.647727
191 TXD 0.410256 0.731707
192 PAP 0.41 0.721519
193 4YB 0.408696 0.707865
194 OVE 0.408602 0.682927
195 ADP BMA 0.407407 0.7375
196 4UV 0.40708 0.740741
197 3AD 0.406977 0.84058
198 AF3 ADP 3PG 0.40678 0.756098
199 A2P 0.40625 0.717949
200 ADJ 0.404959 0.75
201 A A 0.40367 0.734177
202 7MC 0.403361 0.741176
203 8Q2 0.403361 0.663043
204 YLY 0.401575 0.752941
205 4UU 0.4 0.740741
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1IM8; Ligand: SAI; Similar sites found with APoc: 687
This union binding pocket(no: 1) in the query (biounit: 1im8.bio4) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 2PWY SAH None
2 3HVJ 705 None
3 5N5D SAM None
4 5O42 9JW None
5 5O42 BGC None
6 5O42 NAD None
7 1LSS NAD None
8 2FKA BEF None
9 5GWT SIN None
10 2WSB NAD None
11 5GWT NAD None
12 2BVE PH5 None
13 5ZWP GSH None
14 3G2O SAM 0.819672
15 1ZBQ NAD 0.819672
16 2A14 SAH 1.22951
17 5HXI FAD 1.22951
18 5HXI 5HN 1.22951
19 6EQS BV8 1.22951
20 2BD0 NAP 1.22951
21 3QWI NAP 1.22951
22 3QWI CUE 1.22951
23 3RIY NAD 1.22951
24 1X87 NAD 1.27042
25 2YX1 SFG 1.63934
26 3LCV SAM 1.63934
27 4EMI FAD 1.63934
28 4EMI NAD 1.63934
29 4CNK FAD 1.63934
30 2RGJ FAD 1.63934
31 3U4C NDP 1.63934
32 2IZ1 ATR 1.63934
33 5JWC FAD 1.63934
34 3MQ2 SAH 1.83486
35 3BRN SRO 1.91083
36 3VSE SAH 2.04918
37 3FPZ AHZ 2.04918
38 1COY FAD 2.04918
39 3LZW NAP 2.04918
40 1SQF SAM 2.04918
41 3LZW FAD 2.04918
42 1COY AND 2.04918
43 3NYC FAD 2.04918
44 3NYC IAR 2.04918
45 5OJ7 AR6 2.04918
46 1OC2 NAD 2.04918
47 1OC2 TDX 2.04918
48 3TKA SAM 2.04918
49 6EL3 NAP 2.04918
50 6FP4 E1T 2.04918
51 6FP4 FAD 2.04918
52 3U31 NAD 2.04918
53 1EU1 MGD 2.04918
54 1EDO NAP 2.04918
55 1RJW ETF 2.04918
56 5N53 8NB 2.05128
57 1SQL GUN 2.05479
58 3BQF SSM 2.06186
59 4ZCC NAI 2.08333
60 4ZCC FAD 2.08333
61 1YQZ FAD 2.28311
62 5FUB SAH 2.45902
63 1QAN SAH 2.45902
64 2VDV SAM 2.45902
65 3A27 SAM 2.45902
66 1Q0S SAH 2.45902
67 1G55 SAH 2.45902
68 1JQ3 AAT 2.45902
69 1XHC FAD 2.45902
70 6B3A SAM 2.45902
71 3NKS FAD 2.45902
72 5JCM FAD 2.45902
73 5JCM NAD 2.45902
74 5JCM ISD 2.45902
75 1RYI GOA 2.45902
76 4HXY NDP 2.45902
77 5BRT FAD 2.45902
78 5BRT CH9 2.45902
79 1RYI FAD 2.45902
80 4D7E FAD 2.45902
81 2YG3 FAD 2.45902
82 5JAQ NAI 2.45902
83 1ZEM NAD 2.45902
84 5K0A FAD 2.45902
85 6AIN FAD 2.45902
86 4N49 SAM 2.45902
87 4M3P HCS 2.45902
88 5TTJ FAD 2.45902
89 4BJZ FAD 2.45902
90 4BJZ P3A 2.45902
91 2C31 TZD 2.45902
92 2C31 ADP 2.45902
93 1RLZ NAD 2.45902
94 5A3B APR 2.45902
95 5TUK FAD 2.45902
96 1XG5 NAP 2.45902
97 1PJS NAD 2.45902
98 4NTC FAD 2.45902
99 2FR1 NDP 2.45902
100 1G0N PHH 2.45902
101 1G0N NDP 2.45902
102 2RH4 EMO 2.45902
103 1GEG NAD 2.45902
104 2C5A NAD 2.45902
105 2C5A GDC 2.45902
106 1NFQ NAI 2.45902
107 3RFV NAI 2.45902
108 5UFN SAH 2.52101
109 5UAO FAD 2.77264
110 4KRG SAH 2.86885
111 4RVG TYD 2.86885
112 4RVG SAM 2.86885
113 5W7K SAH 2.86885
114 5X62 SAH 2.86885
115 1DL5 SAH 2.86885
116 4YUW 4JU 2.86885
117 5JGL SAM 2.86885
118 4YUW S4M 2.86885
119 5ERG SAM 2.86885
120 1REO FAD 2.86885
121 2IID PHE 2.86885
122 2IID FAD 2.86885
123 5KVA SAM 2.86885
124 4RPL 3UC 2.86885
125 4RPL FAD 2.86885
126 5BJX NAD 2.86885
127 5BJX UDP 2.86885
128 1PN0 FAD 2.86885
129 1PN0 IPH 2.86885
130 3S5W FAD 2.86885
131 4JNA FAD 2.86885
132 4BV6 FAD 2.86885
133 1Q9I TEO 2.86885
134 1Q9I FAD 2.86885
135 4Y9D NAI 2.86885
136 2XOC ADP 2.86885
137 4TM3 FAD 2.86885
138 4YAC NAI 2.86885
139 2E5V FAD 2.86885
140 5KMS NAD 2.86885
141 1PS9 FAD 2.86885
142 5KMS FAD 2.86885
143 4AT0 FAD 2.86885
144 4ZRN UPG 2.86885
145 4ZRN NAD 2.86885
146 4YSX FAD 2.86885
147 2Q1W NAD 2.86885
148 4FN4 NAD 2.86885
149 3KB6 LAC 2.86885
150 4ITU NAI 2.86885
151 4ITU 1HS 2.86885
152 1GTE FAD 2.86885
153 1OAA OAA 2.86885
154 1E6W NAD 2.86885
155 3RKR NAP 2.86885
156 5F2K OCA 3.26087
157 5F2K SAH 3.26087
158 5U19 827 3.27869
159 5U19 SAH 3.27869
160 2EJU SAH 3.27869
161 5MW4 5JU 3.27869
162 3QOX SAH 3.27869
163 3C6K SPD 3.27869
164 3TKY SAH 3.27869
165 2PT9 2MH 3.27869
166 3C6K MTA 3.27869
167 2PT9 S4M 3.27869
168 2I7C AAT 3.27869
169 3L9W AMP 3.27869
170 3GF4 FAD 3.27869
171 1Y8Q ATP 3.27869
172 3GF4 UPG 3.27869
173 1NW5 SAM 3.27869
174 2Z3Y F2N 3.27869
175 1RSG FAD 3.27869
176 3L9W GSH 3.27869
177 5W7R SAH 3.27869
178 1QO8 FAD 3.27869
179 3X0V FAD 3.27869
180 4YNU FAD 3.27869
181 4YNU LGC 3.27869
182 4MIG G3F 3.27869
183 6ER9 FAD 3.27869
184 6ER9 NAP 3.27869
185 4REP FAD 3.27869
186 3UCL FAD 3.27869
187 3UCL CYH 3.27869
188 3UCL NAP 3.27869
189 5I39 FAD 3.27869
190 3AYI FAD 3.27869
191 3AYI HCI 3.27869
192 4UZI IMD 3.27869
193 5J60 FAD 3.27869
194 4J36 1HR 3.27869
195 4J36 FAD 3.27869
196 1YXM ADE 3.27869
197 5KOX RFP 3.27869
198 5KOX FAD 3.27869
199 4D5G FAD 3.27869
200 4D5G TPP 3.27869
201 3K7M FAD 3.27869
202 2B9W FAD 3.27869
203 4YKG FAD 3.27869
204 4YKG NAD 3.27869
205 4M52 M52 3.27869
206 2GN4 NDP 3.27869
207 3OZ2 FAD 3.27869
208 4YAG NAI 3.27869
209 5W7R 9Z7 3.27869
210 1S7G APR 3.27869
211 1RZM E4P 3.27869
212 5THQ NDP 3.27869
213 1FL2 FAD 3.27869
214 1ZK4 NAP 3.27869
215 4M52 FAD 3.27869
216 3WDM ADN 3.27869
217 2GMH FAD 3.27869
218 2AF6 BRU 3.27869
219 4CQM NAP 3.27869
220 1DSS NAD 3.27869
221 2A8X FAD 3.27869
222 1BXK NAD 3.27869
223 1UAY ADN 3.30579
224 4POO SAM 3.5
225 1R18 SAH 3.52423
226 1L3I SAH 3.64583
227 3JWH SAH 3.68664
228 3PFG SAM 3.68852
229 3PFG TLO 3.68852
230 4NEC SAH 3.68852
231 5JJR SAH 3.68852
232 6B92 SAH 3.68852
233 5BW4 SAM 3.68852
234 4MO2 FDA 3.68852
235 1G60 SAM 3.68852
236 1BC5 SAH 3.68852
237 4MO2 FAD 3.68852
238 1NAA ABL 3.68852
239 1NAA 6FA 3.68852
240 4HA6 FAD 3.68852
241 3SQP FAD 3.68852
242 4B63 FAD 3.68852
243 4B63 ORN 3.68852
244 4B63 NAP 3.68852
245 2JB2 FAD 3.68852
246 2JB2 PHE 3.68852
247 3T31 DCQ 3.68852
248 3T31 FAD 3.68852
249 5NMX NAP 3.68852
250 5NMX FAD 3.68852
251 6FDF SAH 3.68852
252 1LVL NAD 3.68852
253 2Q28 ADP 3.68852
254 2WET FAD 3.68852
255 3PPQ CHT 3.68852
256 1BZL FAD 3.68852
257 4D1J DGJ 3.68852
258 6DEN FAD 3.68852
259 6DEN G8A 3.68852
260 6DEN TP9 3.68852
261 1TZD ADP 3.68852
262 3LAD FAD 3.68852
263 3D3W NAP 3.68852
264 1PR9 NAP 3.68852
265 5WKC FAD 3.68852
266 2PXX SAH 3.72093
267 3BGD SAH 3.84615
268 3BGD PM6 3.84615
269 5XLX SAH 3.90071
270 1NM5 NAP 3.94089
271 1NM5 NAD 3.94089
272 3FZG SAM 4
273 5CUQ NSC 4.09836
274 3EVF SAH 4.09836
275 3EVF GTA 4.09836
276 3LKZ SFG 4.09836
277 1FP2 SAH 4.09836
278 3GEG NAD 4.09836
279 1UWK NAD 4.09836
280 1UWK URO 4.09836
281 3QJ4 FAD 4.09836
282 1FP2 HMO 4.09836
283 5MBX SP5 4.09836
284 5MBX FAD 4.09836
285 2DKH 3HB 4.09836
286 2DKH FAD 4.09836
287 3CTY FAD 4.09836
288 2XVE FAD 4.09836
289 2GV8 FAD 4.09836
290 1VQW FAD 4.09836
291 2GVC FAD 4.09836
292 2BRY FAD 4.09836
293 1YBH FAD 4.09836
294 2YVF NAD 4.09836
295 2YVF FAD 4.09836
296 2XVF FAD 4.09836
297 4USR FAD 4.09836
298 2DTX BMA 4.09836
299 1R6D NAD 4.09836
300 1R6D DAU 4.09836
301 2QA1 FAD 4.09836
302 3ZV6 NAD 4.09836
303 4NTD FAD 4.09836
304 3ZV6 4HB 4.09836
305 5DF1 NAP 4.09836
306 5DF1 58X 4.09836
307 1KYQ NAD 4.09836
308 2YVJ FAD 4.09836
309 2ZIF SAM 4.09836
310 2UYQ SAM 4.09836
311 4NBU NAI 4.09836
312 2Q1S NAI 4.09836
313 5UR0 NAD 4.09836
314 6CZ7 MGD 4.2735
315 1PNO NAP 4.44444
316 6C8R SAH 4.5082
317 6C8R EQV 4.5082
318 1L1E SAH 4.5082
319 5W7M SAH 4.5082
320 2O07 SPD 4.5082
321 2IVD FAD 4.5082
322 1YY5 FAD 4.5082
323 2O07 MTA 4.5082
324 4IV9 FAD 4.5082
325 3UOY NAP 4.5082
326 3UOY FAD 4.5082
327 3ICT FAD 4.5082
328 1FEC FAD 4.5082
329 3ICS FAD 4.5082
330 3ICR FAD 4.5082
331 2JHP SAH 4.5082
332 4KGD FAD 4.5082
333 4TQG NDP 4.5082
334 4KGD TDP 4.5082
335 3ICT ADP 4.5082
336 4FC7 COA 4.5082
337 4FC7 NAP 4.5082
338 3ICS ADP 4.5082
339 5AHO TLA 4.5082
340 2IV2 MGD 4.5082
341 3NTD FAD 4.5082
342 5LOG SAH 4.72103
343 3LXD FAD 4.81928
344 5FJN BE2 4.82456
345 5FJN FAD 4.82456
346 4GQB 0XU 4.91803
347 1KPG SAH 4.91803
348 5THY SAH 4.91803
349 5THZ SAH 4.91803
350 5HSA FAS 4.91803
351 4RSL FAD 4.91803
352 1H82 FAD 4.91803
353 1H82 GZZ 4.91803
354 1ZK7 FAD 4.91803
355 2RGO FAD 4.91803
356 3G5S FAD 4.91803
357 4EIP FAD 4.91803
358 1BDB NAD 4.91803
359 4LH7 1X8 4.91803
360 1UDB UFG 4.91803
361 1UDB NAD 4.91803
362 6BWL NAD 4.91803
363 4V3I ASP LEU THR ARG PRO 4.91803
364 4UCI SAM 4.91803
365 1O97 AMP 4.92424
366 1O97 FAD 4.92424
367 3ML1 MGD 5.18518
368 3FPF TNA 5.32787
369 5YJF SAH 5.32787
370 5YJI 8WO 5.32787
371 5YJI SAH 5.32787
372 3FPF MTA 5.32787
373 5YJF 8WO 5.32787
374 2GAG NAD 5.32787
375 6H3O FAD 5.32787
376 4MOP 2H5 5.32787
377 4XQC 13D 5.32787
378 4XQC NAD 5.32787
379 3QVP FAD 5.32787
380 5BUK FAD 5.32787
381 2GAG FAD 5.32787
382 3IHG FAD 5.32787
383 2GAG FOA 5.32787
384 1MO9 FAD 5.32787
385 4USQ FAD 5.32787
386 1MO9 KPC 5.32787
387 2NPX NAD 5.32787
388 2NPX FAD 5.32787
389 3NTA FAD 5.32787
390 1KNR FAD 5.32787
391 6BR8 PGV 5.32787
392 3OU2 SAH 5.50459
393 3NUG NAD 5.66802
394 5ULP KB1 5.7377
395 5HJM MTA 5.7377
396 1U2Z SAH 5.7377
397 3PT9 SAH 5.7377
398 5BVA FAD 5.7377
399 5TUF TDC 5.7377
400 1I8T FAD 5.7377
401 1D4D FAD 5.7377
402 2R4J FAD 5.7377
403 2R4J 13P 5.7377
404 4Z24 FAD 5.7377
405 5TUF FAD 5.7377
406 4K5S FAD 5.7377
407 4K5S PM0 5.7377
408 1GY8 NAD 5.7377
409 5NM7 GLY 5.7377
410 4JDR FAD 5.7377
411 4Z0H NAD 5.7377
412 1JG3 ADN 5.95745
413 2BZG SAH 6.03448
414 6GAS FAD 6.0423
415 5FA5 MTA 6.14754
416 3S1S SAH 6.14754
417 2PX8 SAH 6.14754
418 3HDY FAD 6.14754
419 3HDY GDU 6.14754
420 3HDY FDA 6.14754
421 2CDU ADP 6.14754
422 5IL1 SAM 6.14754
423 5K7U SAM 6.14754
424 4X9M FAD 6.14754
425 2CDU FAD 6.14754
426 2HQM FAD 6.14754
427 5EB4 FAD 6.14754
428 4U8P UDP 6.14754
429 3GMB FAD 6.14754
430 4U8P FDA 6.14754
431 2VVM FAD 6.14754
432 2VVL FAD 6.14754
433 2NVK FAD 6.14754
434 1GET FAD 6.14754
435 1GET NAP 6.14754
436 4X7Y SAH 6.14754
437 1XKQ NDP 6.14754
438 4RDH AMP 6.14754
439 2V3V MGD 6.14754
440 4RDI ATP 6.14754
441 5N0J FAD 6.26781
442 4K79 GAL A2G 6.36364
443 4EMJ FAD 6.54206
444 1F3L SAH 6.55738
445 4LWP SAH 6.55738
446 1XTP SAI 6.55738
447 4OBW SAM 6.55738
448 5E72 SAM 6.55738
449 5YF1 SFG 6.55738
450 5YF1 8V0 6.55738
451 4OPC PGT 6.55738
452 4OPC FDA 6.55738
453 1GPE FAD 6.55738
454 2Q7V FAD 6.55738
455 1E6E FAD 6.55738
456 1E1M NAP 6.55738
457 1E1M FAD 6.55738
458 2C7G ODP 6.55738
459 2C7G FAD 6.55738
460 2ZXI FAD 6.55738
461 3F8D FAD 6.55738
462 4CS9 AMP 6.87831
463 4XUC 43G 6.88073
464 4XUC SAM 6.88073
465 2CUL FAD 6.89655
466 2HMT NAI 6.94444
467 5GWX SAR 6.96721
468 5GWX SAM 6.96721
469 3P9C SAH 6.96721
470 3A25 SAM 6.96721
471 2WA2 SAM 6.96721
472 3KLJ FAD 6.96721
473 5TWB FAD 6.96721
474 3MAG SAH 6.96721
475 3MCT SAH 6.96721
476 3WGT QSC 6.96721
477 3WGT FAD 6.96721
478 5XNC MTA 6.96721
479 4D79 ATP 6.96721
480 6CI9 F3V 6.96721
481 3FG2 FAD 6.96721
482 3Q9T FAY 6.96721
483 2VT3 ATP 6.97674
484 4J56 FAD 7.01754
485 3AD8 NAD 7.07071
486 3AD8 FAD 7.07071
487 3AD8 PYC 7.07071
488 4YMH SAH 7.08333
489 3BXO SAM 7.11297
490 4P7U 1PS 7.14286
491 3C3Y SAH 7.173
492 3LST SAH 7.37705
493 1ZGA SAH 7.37705
494 3GD4 FAD 7.37705
495 3GD4 NAD 7.37705
496 5ZYN FAD 7.37705
497 3AB1 FAD 7.37705
498 2Y6Q FAD 7.37705
499 2Y6Q I7T 7.37705
500 5MLR GRQ 7.37705
501 5MLR NAP 7.37705
502 2GDZ NAD 7.37705
503 3H8V ATP 7.37705
504 5U8U FAD 7.37705
505 5E1M SAH 7.46888
506 5E1M PRO PRO LYS ARG ILE ALA 7.46888
507 1EFV FAD 7.78689
508 1EFV AMP 7.78689
509 1KYZ SAH 7.78689
510 6F97 FAD 7.78689
511 5VN0 NAI 7.78689
512 5VN0 FAD 7.78689
513 4YRY FAD 7.78689
514 3ZNN 4WL 7.78689
515 3ZNN FAD 7.78689
516 1KYZ FER 7.78689
517 5MZI FYK 7.78689
518 5MZI FAD 7.78689
519 5Y77 FAD 7.78689
520 5X68 FAD 7.78689
521 4YRY NAD 7.78689
522 5EJ2 NAD 7.78689
523 1I1N SAH 7.9646
524 6DUB SAH 8.10811
525 5BSZ SAH 8.19672
526 4EUE NAI 8.19672
527 3E1T FAD 8.19672
528 2AQJ FAD 8.19672
529 2AQJ TRP 8.19672
530 3ELW SAM 8.33333
531 3ELW GP3 8.33333
532 3MB5 SAM 8.60656
533 3P2E SAH 8.60656
534 4D04 NAP 8.60656
535 4D04 FAD 8.60656
536 4HSU FAD 8.60656
537 4GUT FAD 8.60656
538 4FWE FAD 8.60656
539 4GUS FAD 8.60656
540 5YU3 NAD 8.60656
541 6FHO FAD 8.60656
542 5YU3 PRO 8.60656
543 6DNT NAD 8.60656
544 1U7T TDT 8.60656
545 6ARJ BW4 9.01639
546 5DX8 SFG 9.01639
547 6ARJ SAH 9.01639
548 5DWQ SFG 9.01639
549 5DXA SFG 9.01639
550 5DX0 SFG 9.01639
551 5DX1 SFG 9.01639
552 5WGR FAD 9.01639
553 3GDN FAD 9.01639
554 3GDN HBX 9.01639
555 3CGB FAD 9.01639
556 2RAB NAD 9.01639
557 2RAB FAD 9.01639
558 3OID NDP 9.01639
559 5MGZ SAH 9.32203
560 5FTW SAH 9.42623
561 6GFK SAH 9.42623
562 3CGD FAD 9.42623
563 3CGD COA 9.42623
564 5OC1 FAD 9.42623
565 3CGD NAD 9.42623
566 2V6G NAP 9.42623
567 5XWV NDP 9.42623
568 1GZ6 NAI 9.42623
569 5XWV 8H6 9.42623
570 2HNK SAH 9.62343
571 3WV8 ATP 9.63303
572 5TVI O8N 9.78261
573 5E8J SAH 9.83607
574 5E9W SAH 9.83607
575 3GCZ SAM 9.83607
576 4E70 N7I 9.83607
577 5MIT NAP 9.83607
578 5MIT FAD 9.83607
579 2EWM NAD 9.83607
580 6F7L FAD 9.83607
581 1V5F FAD 9.83607
582 1V5F TPP 9.83607
583 1DMR PGD 9.83607
584 5L95 AMP 10
585 2XVM SAH 10.0503
586 5ICE 2H4 10.2459
587 5ICE SAH 10.2459
588 4C3Y FAD 10.2459
589 5G3U FDA 10.2459
590 4C3Y ANB 10.2459
591 5G3U ITW 10.2459
592 4DMG SAM 10.6557
593 1ELI PYC 10.6557
594 3RNM FAD 10.6557
595 3QFA FAD 10.6557
596 5J5Z FAD 10.6557
597 2Q0L FAD 10.6557
598 1XCL SAH 11.0638
599 1I9G SAM 11.0656
600 1SB8 UD2 11.0656
601 1SB8 NAD 11.0656
602 2DQA NAG NAG NAG 11.2903
603 4AZW SAM 11.4754
604 4DCM SAM 11.4754
605 4BLW AMP 11.4754
606 4BLW SAH 11.4754
607 1IY8 NAD 11.4754
608 5FWA J7C 11.8852
609 1RP0 AHZ 11.8852
610 1SW1 PBE 11.8852
611 1G8K MGD 12.0301
612 2OBF SAH 12.2951
613 2OBF F83 12.2951
614 3H2B SAH 12.3153
615 2ZFU SAH 12.5581
616 1JQD SAH 12.7049
617 2AOT SAH 12.7049
618 1JQD HSM 12.7049
619 5GSN FAD 12.7049
620 5GSN NAP 12.7049
621 5GSN MMZ 12.7049
622 1P1C SAH 13.0653
623 4KRI SAH 13.1148
624 4PIO SAH 13.1148
625 4PIO AVI 13.1148
626 4AP3 FAD 13.1148
627 4AP3 NAP 13.1148
628 4L2I FAD 13.1148
629 4II2 ATP 13.253
630 2P41 SAH 13.7705
631 6BQ6 TER 13.9344
632 3AXB PRO 13.9344
633 3AXB FAD 13.9344
634 1Q1R FAD 13.9344
635 1XHL NDP 13.9344
636 2CHT TSA 14.1732
637 5MPT SAH 14.3443
638 2DPM SAM 14.7541
639 5DNK SAH 15.1639
640 5ODQ FAD 15.2174
641 4KIB SAH 15.5738
642 1XDS SAM 15.5738
643 3EVG SAH 15.9836
644 3VYW SAM 15.9836
645 1V59 FAD 15.9836
646 5JCA FAD 15.9836
647 5JCA NDP 15.9836
648 1V59 NAD 15.9836
649 3Q87 SAM 16
650 3DXY SAM 16.055
651 5F8F SFG 16.3934
652 1FP1 SAH 16.8033
653 2F5Z FAD 17.1875
654 5FA8 SAM 17.3913
655 5GM1 SAH 17.623
656 6ECT SAM 18.0328
657 6ECU SAH 18.4426
658 5MLJ 9ST 18.75
659 6ECW SAH 18.8525
660 1QZZ SAM 18.8525
661 6GAR FAD 18.8525
662 4TXI FAD 18.8525
663 3CH6 NAP 18.8525
664 3CH6 311 18.8525
665 5TS5 FAD 19.2623
666 3GWZ SAH 19.2623
667 3GXO SAH 19.2623
668 4A6D SAM 19.6721
669 5JE0 AZ8 20.082
670 5JE0 SAH 20.082
671 5T67 SAH 20.082
672 5T67 JHZ 20.082
673 1TPY SAH 20.4918
674 4PNE SAH 21.3115
675 6GKV SAH 21.7213
676 5WP4 SAH 22.1311
677 1KPH SAH 22.1311
678 4R6W PC 22.541
679 4R6W SAH 22.541
680 1Z3C SA8 22.9508
681 1VE3 SAM 24.6696
682 6F5Z SAH 25
683 6C5B SAH 25
684 5KOK SAH 26.2295
685 5KOK S9T 26.2295
686 5KOK R9T 26.2295
687 3T7S SAM 29.5082
Pocket No.: 2; Query (leader) PDB : 1IM8; Ligand: SAI; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1im8.bio4) has 23 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1IM8; Ligand: SAI; Similar sites found with APoc: 1
This union binding pocket(no: 3) in the query (biounit: 1im8.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 4OX5 DAL None
Pocket No.: 4; Query (leader) PDB : 1IM8; Ligand: SAI; Similar sites found with APoc: 49
This union binding pocket(no: 4) in the query (biounit: 1im8.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1NJR XYL 1.63934
2 4YH2 GSH 1.8018
3 2ZWI C5P 2.04918
4 4D52 GXL 2.45902
5 2GMV PEP 2.45902
6 4D52 GIV 2.45902
7 4URF NAD 2.45902
8 3EYA FAD 2.45902
9 3RFV 15L 2.45902
10 1UKG MMA 2.86885
11 5Z75 NAD 2.86885
12 1E3W NAD 2.86885
13 4DSG FAD 2.86885
14 4DSG UDP 2.86885
15 3CV2 OXL 2.86885
16 4BUZ OCZ 2.86885
17 4BUZ OAD 2.86885
18 4IA6 EIC 2.86885
19 4BUZ NAD 2.86885
20 2WHL MAN BMA BMA 2.86885
21 1Q8S MAN MMA 2.86885
22 4QAR ADE 2.98507
23 2AJH MET 3.06122
24 2GN4 UD1 3.27869
25 1H16 PYR 3.68852
26 1BZL GCG 3.68852
27 1I2B NAD 3.68852
28 1I2B UPG 3.68852
29 1I2B USQ 3.68852
30 1LVL FAD 3.68852
31 1FUR MLT 4.09836
32 3NT6 FAD 4.09836
33 1Z45 NAD 4.09836
34 3BY9 SIN 4.5082
35 4Y7E BMA BMA BMA 4.91803
36 1D8C GLV 6.96721
37 2PZM NAD 6.96721
38 2PZM UDP 6.96721
39 6CI9 NAP 6.96721
40 2YY7 NAD 7.05128
41 2WPF FAD 8.60656
42 2WPF WPF 8.60656
43 4J1Q NDP 9.42623
44 5DYO FLU 9.63303
45 4UEC MGT 9.78261
46 1JNR FAD 10.6557
47 5T48 MGP 10.9375
48 4PNG GSF 12.2271
49 5WP4 PC 22.1311
Pocket No.: 5; Query (leader) PDB : 1IM8; Ligand: SAI; Similar sites found with APoc: 1
This union binding pocket(no: 5) in the query (biounit: 1im8.bio3) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1OCU PIB 4.93827
Pocket No.: 6; Query (leader) PDB : 1IM8; Ligand: SAI; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1im8.bio3) has 23 residues
No: Leader PDB Ligand Sequence Similarity
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