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Receptor
PDB id Resolution Class Description Source Keywords
1H72 1.8 Å EC: 2.7.1.39 CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE METHANOCOCCUS JANNASCHII TRANSFERASE KINASE THREONINE BIOSYNTHESIS
Ref.: STRUCTURAL BASIS FOR THE CATALYSIS AND SUBSTRATE SPECIFICITY OF HOMOSERINE KINASE BIOCHEMISTRY V. 40 10810 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP C:1301;
Invalid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
HSE C:1300;
Valid;
none;
submit data
119.119 C4 H9 N O3 C(CO)...
TRS C:1302;
Invalid;
none;
submit data
122.143 C4 H12 N O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1H74 1.9 Å EC: 2.7.1.39 CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE METHANOCOCCUS JANNASCHII TRANSFERASE KINASE
Ref.: STRUCTURAL BASIS FOR THE CATALYSIS AND SUBSTRATE SPECIFICITY OF HOMOSERINE KINASE BIOCHEMISTRY V. 40 10810 2001
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1H72 - HSE C4 H9 N O3 C(CO)[C@@H....
2 1FWK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 1H73 - THR C4 H9 N O3 C[C@H]([C@....
4 1H74 - ILE C6 H13 N O2 CC[C@H](C)....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1H72 - HSE C4 H9 N O3 C(CO)[C@@H....
2 1FWK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 1H73 - THR C4 H9 N O3 C[C@H]([C@....
4 1H74 - ILE C6 H13 N O2 CC[C@H](C)....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1H72 - HSE C4 H9 N O3 C(CO)[C@@H....
2 1FWK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 1H73 - THR C4 H9 N O3 C[C@H]([C@....
4 1H74 - ILE C6 H13 N O2 CC[C@H](C)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HSE; Similar ligands found: 45
No: Ligand ECFP6 Tc MDL keys Tc
1 HSE 1 1
2 SER 0.590909 0.821429
3 DSN 0.590909 0.821429
4 DAB 0.583333 0.766667
5 API 0.56 0.677419
6 NVA 0.56 0.666667
7 HCS 0.56 0.821429
8 DBB 0.521739 0.62069
9 2RA 0.521739 0.733333
10 ABA 0.521739 0.62069
11 GLN 0.518519 0.6875
12 DGL 0.518519 0.758621
13 GLU 0.518519 0.758621
14 DGN 0.518519 0.6875
15 GGL 0.518519 0.758621
16 C2N 0.5 0.655172
17 ORN 0.5 0.733333
18 DCY 0.5 0.75
19 CYS 0.5 0.75
20 NLE 0.482759 0.625
21 ONL 0.482759 0.6875
22 ASN 0.48 0.666667
23 ASP 0.48 0.758621
24 DAS 0.48 0.758621
25 MET 0.466667 0.617647
26 11C 0.466667 0.733333
27 MSE 0.466667 0.6
28 DLY 0.466667 0.709677
29 UN1 0.466667 0.733333
30 MED 0.466667 0.617647
31 LYS 0.451613 0.6875
32 DHH 0.451613 0.709677
33 AS2 0.444444 0.75
34 CSO 0.444444 0.676471
35 ONH 0.4375 0.648649
36 NPI 0.4375 0.709677
37 CSS 0.428571 0.625
38 6CL 0.424242 0.65625
39 2FM 0.424242 0.636364
40 26P 0.424242 0.666667
41 MEQ 0.424242 0.611111
42 HL5 0.419355 0.793103
43 CME 0.411765 0.705882
44 CIR 0.411765 0.605263
45 MF3 0.411765 0.617647
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1H74; Ligand: ILE; Similar sites found with APoc: 67
This union binding pocket(no: 1) in the query (biounit: 1h74.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 2PHN GDP 1.5748
2 3LXD FAD 1.68919
3 1V25 ANP 1.68919
4 6C3C EJ1 2.36486
5 2YG3 FAD 2.36486
6 2R5V HHH 2.36486
7 1ORR NAD 2.36486
8 3X44 PUS 2.36486
9 4D57 ARG AMP 2.36486
10 4LZJ 22H 2.36486
11 1WVG APR 2.36486
12 1EQ2 NAP 2.36486
13 3RFV NAI 2.62172
14 3RFV 15L 2.62172
15 4GKV NAD 2.7027
16 6C8T EQJ 3.04054
17 6C92 EQJ 3.04054
18 2A8X FAD 3.04054
19 4GUT FAD 3.04054
20 4AZJ SEP PLP 3.04054
21 5Z2L NDP 3.26531
22 6CUZ FEV 3.37838
23 2VBF TPP 3.37838
24 1VJO PLP 3.37838
25 3WBF API 3.37838
26 2FCR FMN 3.46821
27 4KXQ APR 3.55872
28 3WQQ NDP 3.71622
29 3WQQ IB3 3.71622
30 4KP7 1UQ 3.71622
31 4KP7 NAP 3.71622
32 4K2M O1G 4.05405
33 3NUB UD0 4.05405
34 6C8R SAH 4.05405
35 1AJS PLA 4.05405
36 5Z21 NAI 4.05405
37 1XG5 NAP 4.30108
38 5UY8 8UM 4.39189
39 5UY8 AMZ 4.39189
40 3L4S NAD 4.39189
41 2GZ3 NAP 4.72973
42 3S1S SAH 5.40541
43 3VC3 C6P 5.81395
44 5NII FAD 6.14887
45 5I60 67W 6.41892
46 3DAA PDD 6.41892
47 6FAA ADP 6.41892
48 2Q0L NAP 6.41892
49 5BSH PRO 6.4982
50 3K7M FAD 6.75676
51 5OE4 3UK 6.75676
52 3OBK PBG 6.75676
53 5JP0 BGC 6.75676
54 5MHB PBG 7.09459
55 1P9B IMO 7.09459
56 4IVN BMX 7.19424
57 5NUE NAD 7.43243
58 3NKS FAD 7.77027
59 2Q16 ITT 7.77027
60 3FSJ D7K 8.78378
61 5VEG FMN 8.98876
62 3PC3 P1T 9.67742
63 3B8X G4M 10.473
64 4YC0 5OF 10.8787
65 3TWO NDP 11.1486
66 1VE3 SAM 12.3348
67 1J5P NAD 13.5135
Pocket No.: 2; Query (leader) PDB : 1H74; Ligand: ILE; Similar sites found with APoc: 81
This union binding pocket(no: 2) in the query (biounit: 1h74.bio2) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 1LNX URI None
2 5OCM 9RH 1.03093
3 4XO8 KGM 1.26582
4 2HW1 FRU 1.68919
5 6G47 SIA 1.91388
6 6G47 SIA SIA 1.91388
7 5DNC ASN 2.02703
8 4U00 ADP 2.04918
9 5LTJ ADP 2.36486
10 5W6Y TRP 2.36486
11 4CCW VKC 2.7027
12 5MZI FYK 2.7027
13 1F9V ADP 2.88184
14 5DT6 GLU 2.99625
15 3COB ADP 3.04054
16 6A20 ADP 3.04054
17 1G6H ADP 3.11284
18 3AI8 HNQ 3.125
19 3GD8 GOL 3.13901
20 5NXX 3Q7 3.35821
21 2A2C ADP 3.37838
22 2A2C NG1 3.37838
23 1YQT ADP 3.37838
24 2AWN ADP 3.41207
25 1S9A BEZ 3.50195
26 2X5F PLP 3.71622
27 2XT3 ADP 3.71622
28 4ZNO SUC 3.71622
29 1OS7 TAU 3.88693
30 5YW5 ADE 3.91061
31 5TQZ GLC 4
32 2CZL TLA 4.04412
33 2JK0 ASP 4.05405
34 3NHB ADP 4.05405
35 4FRZ ADP 4.05405
36 4YMU ATP 4.09091
37 4QM7 GTP 4.09357
38 5B5S BOG 4.34783
39 2WTN FER 4.38247
40 2OG2 MLI 4.39189
41 2JBM SRT 4.39189
42 3B9Q MLI 4.63576
43 2BOY BHO 4.72441
44 2GK6 ADP 4.72973
45 4MDB RLT 4.88889
46 5GVR LMR 5.12821
47 2F6U CIT 5.12821
48 4R2I ANP 5.2381
49 2PZE ATP 5.24017
50 2R42 FPS 5.40541
51 3V2U ATP 5.40541
52 5YW0 SIN 5.40541
53 3I7S PYR 5.40541
54 2AJ4 ANP 5.74324
55 4A59 AMP 6.08108
56 1JJ7 ADP 6.15385
57 3B5J 12D 6.17284
58 3BP1 GUN 6.2069
59 1NX4 AKG 6.22711
60 5OKU 0L1 6.41892
61 1FNZ A2G 6.75105
62 1QAW TRP 6.75676
63 1WUU ANP 7.01754
64 2HIM ASN 7.09459
65 2ZC0 PMP 7.43243
66 3H4S ADP 8.88889
67 1SOW OXL 9.7973
68 2PYU IMP 9.7973
69 1JI0 ATP 10.4167
70 5Y4R C2E 11.0345
71 2X7I CIT 12.5
72 3ZIA ADP 14.4928
73 1IT7 GUN 14.8649
74 4UTG ANP 15.8784
75 2V2V V12 16.5541
76 2HYQ MAN MAN 17.2131
77 2NU5 NAG 17.2131
78 1XVB BBU 19.5946
79 1OJ4 ANP 22.9682
80 2WW4 ADP 22.9682
81 6MDE MEV 28.3828
Pocket No.: 3; Query (leader) PDB : 1H74; Ligand: ADP; Similar sites found with APoc: 307
This union binding pocket(no: 3) in the query (biounit: 1h74.bio2) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 1OYJ GSH None
2 2IL4 COA None
3 2IMG MLT None
4 1WAP TRP None
5 5C2N NAG 1.01351
6 5OCM 9RH 1.03093
7 4AOA IK2 1.35135
8 2CJW GDP 1.5625
9 2J5V PCA 1.68919
10 1TKU 5RP 1.68919
11 3MD0 GDP 1.68919
12 3I51 45C 1.85185
13 3G5N PB2 2.02703
14 1ZGS XMM 2.02703
15 6F5W KG1 2.02703
16 1XMV ADP 2.02703
17 4U00 ADP 2.04918
18 1TL2 NDG 2.11864
19 3GJ3 GDP 2.26244
20 3GJ0 GDP 2.26244
21 3GJ5 GDP 2.26244
22 5ZI9 FLC 2.30769
23 5MZN ADP 2.36486
24 5LTJ ADP 2.36486
25 2D7D ADP 2.36486
26 4LC1 GDP 2.36486
27 4HE2 AMP 2.36486
28 3DZD ADP 2.36486
29 2G50 ALA 2.36486
30 3ZFD ANP 2.36486
31 2AOU CQA 2.39726
32 4G86 BNT 2.46479
33 1ION ADP 2.46914
34 2IXE ATP 2.58303
35 1U0J ADP 2.62172
36 5NM7 GLY 2.63158
37 1RRC ADP 2.7027
38 3ITJ CIT 2.7027
39 5K8P 6R8 2.7027
40 4KBF AMP 2.7027
41 3RC3 ANP 2.7027
42 4ADC PLP 2.7027
43 4JZ8 CIT 2.7027
44 5CK5 GDP 2.7027
45 3HP9 CF1 2.7027
46 3F81 STT 2.73224
47 3DKP ADP 2.85714
48 2HT6 GDP 2.87356
49 1F9V ADP 2.88184
50 4E03 ADP 2.91262
51 2B4B COA 2.92398
52 5O2J 2PO 2.9304
53 3W5J GDP 2.94118
54 2W58 ADP 2.9703
55 3COB ADP 3.04054
56 6A20 ADP 3.04054
57 4QOS ADP 3.04054
58 3UDG TMP 3.04054
59 4E3Q PMP 3.04054
60 3WMX THR 3.04054
61 5ZBR ANP 3.04054
62 1W31 SHO 3.04054
63 3EC1 GDP 3.04054
64 3CV2 OXL 3.04054
65 5YKT PMP 3.04054
66 1M1B SPV 3.05085
67 1UYY BGC BGC 3.05344
68 5XH2 NPO 3.05344
69 1G6H ADP 3.11284
70 3AI8 HNQ 3.125
71 3GJ8 GDP 3.26087
72 1G3Q ADP 3.37553
73 2A2C ADP 3.37838
74 2A2C NG1 3.37838
75 5YV5 ADP 3.37838
76 1YQT ADP 3.37838
77 5TSH ADP 3.37838
78 3TBK ANP 3.37838
79 2VVG ADP 3.37838
80 5TSH ANP 3.37838
81 4HSE ADP 3.37838
82 5E9G GLV 3.37838
83 5UXH GFB 3.37838
84 2AWN ADP 3.41207
85 5HCN GCP 3.44828
86 1S9A BEZ 3.50195
87 3IUY AMP 3.50877
88 2IYL GDP 3.52113
89 1BO4 COA 3.57143
90 5BQ5 ADP BEF 3.7037
91 2XT3 ADP 3.71622
92 1GOJ ADP 3.71622
93 4XOE KGM 3.71622
94 1Q8S MAN MMA 3.71622
95 4ZM4 PLP 3.71622
96 2FSH ANP 3.71622
97 1UKG MMA 3.71622
98 1DMH MCT 3.71622
99 1Q8Q MAN MMA 3.71622
100 2PHX MAN MAN 3.71622
101 1V8K ANP 3.71622
102 2I6U CP 3.71622
103 1WOQ BGC 3.74532
104 5U32 GDP 3.81356
105 1B0U ATP 3.81679
106 3B7G ANP 3.91304
107 4JLS 3ZE 3.94737
108 4BQS ADP 3.97727
109 3UIE ANP 4
110 5EYW PGA 4.01606
111 3NHB ADP 4.05405
112 3LRE ADP 4.05405
113 4FRZ ADP 4.05405
114 1Z6T ADP 4.05405
115 1WDI CIT 4.05405
116 2IS6 ADP 4.05405
117 2JK0 ASP 4.05405
118 4YJ1 ADP 4.05405
119 5ZXD ATP 4.05405
120 5VHC BEF ADP 4.05405
121 1OFZ FUC 4.05405
122 1OFZ FUL 4.05405
123 3EXS 5RP 4.0724
124 4YMU ATP 4.09091
125 4QM7 GTP 4.09357
126 4WZ6 ATP 4.13793
127 1XX6 ADP 4.18848
128 1R0X ATP 4.1958
129 5B5S BOG 4.34783
130 2WTN FER 4.38247
131 2OG2 MLI 4.39189
132 4AG5 ADP 4.39189
133 4PJ3 ANP 4.39189
134 1JQN DCO 4.39189
135 2JBM SRT 4.39189
136 3DC4 ADP 4.39189
137 3SZB I1E 4.39189
138 4LJ9 ACP 4.39189
139 4Y4V DAL 4.39189
140 1SNN 5RP 4.40529
141 4PX9 ADP 4.45205
142 2QZ4 ADP 4.58015
143 1VHT BA3 4.58716
144 3B9Q MLI 4.63576
145 2BOY BHO 4.72441
146 2GK6 ADP 4.72973
147 3KJI ADP 4.72973
148 1BG2 ADP 4.72973
149 3EWA ANP 4.72973
150 4U0S ADP 4.72973
151 2NNJ 225 4.72973
152 5L3R GCP 4.77816
153 3BFV ADP 4.79705
154 1H65 GDP 4.81482
155 1VG9 GDP 4.86486
156 1I4D GDP 4.91071
157 1TIQ COA 5
158 3LN9 FLC 5.03597
159 2DPY ADP 5.06757
160 2J0W ASP 5.06757
161 1SVI GDP 5.06757
162 5IRN ADP 5.06757
163 1A8U BEZ 5.06757
164 4Z87 GDP 5.06757
165 3FKQ ATP 5.06757
166 2PL3 ADP 5.08475
167 5GVR LMR 5.12821
168 2F6U CIT 5.12821
169 6AIC AMP 5.14019
170 1Z0A GDP 5.17241
171 4KFU ACP 5.18868
172 2J0V GDP 5.18868
173 4R2I ANP 5.2381
174 2PZE ATP 5.24017
175 3V2U ATP 5.40541
176 2R42 FPS 5.40541
177 3TK1 GDP 5.40541
178 3EZ2 ADP 5.40541
179 1T5C ADP 5.40541
180 4WCX ALA 5.40541
181 2ZJ5 ADP 5.40541
182 4RZ3 ADP 5.42373
183 3CYI ATP 5.45455
184 1GXU 2HP 5.49451
185 3PCJ INO 5.5
186 5BXQ GDP 5.51181
187 2F7C CCU 5.5794
188 2Y7I ARG 5.67686
189 3E70 GDP 5.74324
190 3FWY ADP 5.74324
191 2AJ4 ANP 5.74324
192 4P4M D3T 5.74324
193 1SQ5 ADP 5.74324
194 3MWL 8OX 5.7971
195 4LFL TG6 5.81395
196 1O5O U5P 5.88235
197 2OBM ADP 6.08108
198 2ZR9 DTP 6.08108
199 3SHR CMP 6.08108
200 1QHH ATP 6.08696
201 1JJ7 ADP 6.15385
202 3Q9L ATP 6.15385
203 3B5J 12D 6.17284
204 3BP1 GUN 6.2069
205 1JJV ATP 6.31068
206 2WHX ADP 6.41892
207 4PPF FLC 6.41892
208 2JLR ANP 6.41892
209 3UWV 2PG 6.41892
210 3PNL ADP 6.41892
211 6FAA ADP 6.41892
212 5BN3 ADP 6.41892
213 5TB5 GDP 6.48649
214 5TAR GDP 6.48649
215 3T1O GDP 6.56566
216 1KY3 GDP 6.59341
217 2OFW ADX 6.73077
218 4D0N GDP 6.75676
219 5KUT GDP 6.75676
220 5JP0 BGC 6.75676
221 1QAW TRP 6.75676
222 3HY2 ATP 6.79612
223 2D2F ADP 6.8
224 1YRB GDP 6.87023
225 3A4M ADP 6.92308
226 1HTW ADP 6.96203
227 1WUU ANP 7.01754
228 4BA5 PXG 7.09459
229 5JVB 2PO 7.14286
230 4WOH 4NP 7.22892
231 4DID GDP 7.25389
232 2BFR ADP 7.29167
233 4XGU ADP 7.43243
234 1OXV ANP 7.43243
235 5CSS G3P 7.43243
236 1JW0 GUA 7.43243
237 1XKV ATP 7.43243
238 1RZ1 NAD 7.45342
239 6BYF CIT 7.64706
240 3QDW A2G 7.69231
241 2O0J ADP 7.77027
242 3IO3 ADP 7.77027
243 4BTV RB3 7.84884
244 4YEF 4CQ 7.86517
245 2CBZ ATP 8.01688
246 3GJ7 GDP 8.16327
247 2QX0 PH2 8.1761
248 5IDM ANP 8.37989
249 3DUV KDO 8.39695
250 5OCQ CIT 8.78378
251 2CE7 ADP 8.78378
252 2GKS ADP 8.78378
253 3Q85 GNP 8.78378
254 1B7T ADP 8.78378
255 3H4S ADP 8.88889
256 2O66 FLC 8.88889
257 3GJ4 GDP 9.09091
258 3DEF GDP 9.12162
259 4UOX PLP 9.12162
260 3KP6 SAL 9.45946
261 2H7C SIA 9.45946
262 5F1V 3VN 9.45946
263 5O74 GDP 9.64467
264 5Y6N ADP 9.7973
265 3BER AMP 10.0402
266 5O2Z FLC 10.084
267 5L3W GDP 10.1307
268 1JI0 ATP 10.4167
269 5LB3 ADP 10.473
270 1Z03 OCH 10.473
271 1DS6 GDP 10.5556
272 1A8S PPI 10.6227
273 3AB4 THR 10.6742
274 2DTJ THR 10.6742
275 4YDS ATP 10.9649
276 5Y4R C2E 11.0345
277 2WCI GSH 11.1111
278 1W3T 3GR 11.2245
279 4V03 ADP 11.284
280 5WC2 ADP 11.4865
281 6C90 ADP 11.5385
282 1R6B ADP 11.8243
283 4CVN ADP 12.0419
284 5WPJ NDP 12.1622
285 4QYS PLR 12.1622
286 2RCN GDP 12.1622
287 4Z7X 3CX 12.1849
288 2X7I CIT 12.5
289 4IHQ ADP 12.5
290 5L3V GDP 12.5
291 1VBO MAN MAN MAN 12.7517
292 2CDN ADP 12.9353
293 5TCI MLI 13.1757
294 3ZIA ADP 14.4928
295 3Q72 GNP 15.0602
296 3CH5 GDP 15.3846
297 2KIN ADP 15.5462
298 4UTG ANP 15.8784
299 4DCT GDP 15.8784
300 2V2V V12 16.5541
301 1TH8 ADP 18.9655
302 3BY8 MLT 19.7183
303 3PQC GDP 21.0256
304 5J1J ANP 21.4035
305 1OJ4 ANP 22.9682
306 2WW4 ADP 22.9682
307 2Y65 ADP 35
Pocket No.: 4; Query (leader) PDB : 1H74; Ligand: ADP; Similar sites found with APoc: 64
This union binding pocket(no: 4) in the query (biounit: 1h74.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 5KXE 6Y2 None
2 1Y13 BIO 1.65746
3 1GPM AMP 1.68919
4 5FTB ANP 2.02703
5 3KVY R2B 2.02703
6 1M26 GAL A2G 2.25564
7 5JCJ 6JM 2.43056
8 3JQ9 AX1 2.43056
9 4Z2B 4LC 2.7027
10 2XYA 7L4 2.74725
11 1QHG ATP 3.04054
12 4WBD CIT 3.04054
13 6HKE MLT 3.37838
14 4CS9 AMP 3.37838
15 5OVK NDP 3.51562
16 2YPI PGA 3.64372
17 1Q19 SSC 3.71622
18 3OBT SLB 3.71622
19 1KC7 PPR 4.05405
20 3K56 IS3 4.13534
21 1P4A PCP 4.21053
22 1YXM ADE 4.72973
23 3BC9 ACR 4.72973
24 4PC3 GDP 5.06757
25 2I4I AMP 5.06757
26 3P4X ADP 5.06757
27 5LOL GSH 5.11628
28 2VDV SAM 5.28455
29 2IF8 ADP 5.40541
30 5C9P FUC 5.51181
31 5LX9 OLB 5.6338
32 4XJC TTP 5.64972
33 2DVZ GLU 5.74324
34 5W3Y ACO 6.08108
35 1FNZ A2G 6.75105
36 3BD9 A3P 6.75676
37 1Q5H DUD 6.80272
38 5AHW CMP 6.80272
39 5KQA GSH 6.81818
40 5N0L ILE 6.91824
41 1JAY F42 7.07547
42 1DNP MHF 7.09459
43 2HIM ASP 7.09459
44 1WQ1 AF3 7.22892
45 3TD3 GLY 7.31707
46 2V7Q ADP 7.53425
47 3GON ANP 7.76119
48 5E5U MLI 8.10811
49 2WUL GSH 8.47458
50 3EPO MP5 8.78378
51 4TTQ ATP 10.2326
52 4BWL MN9 10.473
53 4YS0 ADP 10.473
54 4KU7 PCG 11.7647
55 4IMG NGF 12.2867
56 5JAX 6J7 12.5926
57 1WK9 TSB 13.0137
58 1O5Q PYR 13.1148
59 1SQL GUN 13.6986
60 2WPB ZZI 14.1892
61 5X2N ALA 15.2074
62 4D86 ADP 16.5541
63 1NBU PH2 16.8067
64 2Y69 CHD 28.5714
Pocket No.: 5; Query (leader) PDB : 1H74; Ligand: ILE; Similar sites found with APoc: 87
This union binding pocket(no: 5) in the query (biounit: 1h74.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 5KXE 6Y2 None
2 4AOA IK2 1.35135
3 2J5V PCA 1.68919
4 1TKU 5RP 1.68919
5 1A99 PUT 2.02703
6 6F5W KG1 2.02703
7 5MZN ADP 2.36486
8 4LC1 GDP 2.36486
9 4G86 BNT 2.46479
10 1U0J ADP 2.62172
11 5NM7 GLY 2.63158
12 3ITJ CIT 2.7027
13 3HP9 CF1 2.7027
14 2W58 ADP 2.9703
15 3CV2 OXL 3.04054
16 4M1U A2G MBG 3.04054
17 4QOS ADP 3.04054
18 5YV5 ADP 3.37838
19 3TBK ANP 3.37838
20 5TSH ADP 3.37838
21 4CS9 AMP 3.37838
22 4DKX GDP 3.7037
23 4ZM4 PLP 3.71622
24 3OBT SLB 3.71622
25 3K4Q IHS 3.71622
26 1B0U ATP 3.81679
27 5ZXD ATP 4.05405
28 2IS6 ADP 4.05405
29 5AWQ GLC GLC 4.05405
30 1KC7 PPR 4.05405
31 5F1H 5U6 4.06504
32 1XX6 ADP 4.18848
33 1R0X ATP 4.1958
34 4PJ3 ANP 4.39189
35 1JQN DCO 4.39189
36 3DC4 ADP 4.39189
37 4AG5 ADP 4.39189
38 3KIF GDL 4.71698
39 1YXM ADE 4.72973
40 3KJI ADP 4.72973
41 1P7T PYR 4.72973
42 4U0S ADP 4.72973
43 4U36 TNR 5
44 1K4M CIT 5.06757
45 3FU7 D2M 5.06757
46 3R7F CP 5.06757
47 4KFU ACP 5.18868
48 5TDC NMM ILE PHE SER 5.26316
49 2IF8 ADP 5.40541
50 3TK1 GDP 5.40541
51 3CYI ATP 5.45455
52 1GXU 2HP 5.49451
53 2F7C CCU 5.5794
54 3TTM PUT 5.74324
55 2OBM ADP 6.08108
56 5W3Y ACO 6.08108
57 4TWL ASC 6.09756
58 1JJV ATP 6.31068
59 5KSP GDP 6.31579
60 4PPF FLC 6.41892
61 2WHX ADP 6.41892
62 2JLR ANP 6.41892
63 5KUT GDP 6.75676
64 3HY2 ATP 6.79612
65 2D2F ADP 6.8
66 5KQA GSH 6.81818
67 5N0L ILE 6.91824
68 3A4M ADP 6.92308
69 1HTW ADP 6.96203
70 1DNP MHF 7.09459
71 5JVB 2PO 7.14286
72 3TD3 GLY 7.31707
73 1LTH OXM 7.43243
74 3GON ANP 7.76119
75 2CBZ ATP 8.01688
76 4V03 ADP 11.284
77 6C90 ADP 11.5385
78 4CVN ADP 12.0419
79 5WPJ NDP 12.1622
80 4IMG NGF 12.2867
81 2WPB ZZI 14.1892
82 2KIN ADP 15.5462
83 4D86 ADP 16.5541
84 5ZCO CHD 20.1835
85 5Z84 CHD 20.1835
86 2Y69 CHD 28.5714
87 2Y65 ADP 35
Pocket No.: 6; Query (leader) PDB : 1H74; Ligand: ILE; Similar sites found with APoc: 72
This union binding pocket(no: 6) in the query (biounit: 1h74.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 3UZO GLU 1.68919
2 2IVN ANP 2.02703
3 1DUB CAA 2.29885
4 3OZ2 FAD 2.36486
5 2IVD FAD 2.7027
6 4DPL NAP 2.7027
7 1NVT NAP 2.78746
8 2CUL FAD 3.01724
9 2VTD LKM 3.04054
10 3LZW NAP 3.04054
11 4HA6 FAD 3.04054
12 3AFH GSU 3.04054
13 3HDY FAD 3.37838
14 3HDY GDU 3.37838
15 3HDY FDA 3.37838
16 1PHP ADP 3.37838
17 6AMI TRP 3.37838
18 2P4S DIH 3.37838
19 3A28 NAD 3.48837
20 1CQ1 PQQ 3.71622
21 1CQ1 BGC 3.71622
22 6BWL NAD 3.71622
23 2EXK XYS XYS 3.71622
24 5W19 9TD 3.71622
25 16PK BIS 4.05405
26 4NMC 2OP 4.05405
27 2ZGY GDP 4.39189
28 2GMV UN8 4.39189
29 4QED NAP 4.39189
30 1RJW ETF 4.39189
31 5EIB GTP 4.39189
32 1ZPD DPX 4.39189
33 1M2K APR 4.41767
34 6DEF GCP 4.72973
35 5TUF FAD 4.72973
36 4FDV 0UK 5.26316
37 6C28 WCA 5.37634
38 2Q7V FAD 5.40541
39 2D3S TNR 5.78512
40 1V97 MTE 6.08108
41 4LNL PLG 6.08108
42 4LNL 2BO 6.08108
43 4LNL 2BK 6.08108
44 4YDU ADP 6.41892
45 2QTR NXX 6.87831
46 1V59 FAD 7.09459
47 1FL2 FAD 7.09459
48 5OOH NAP 7.28155
49 5OOH 9ZZ 7.28155
50 3L9W AMP 7.43243
51 1A27 NAP 7.61246
52 2ZXI FAD 7.77027
53 3O84 HTJ 7.77027
54 3WV8 ATP 8.25688
55 3EXH TPP 8.63874
56 4P6G 2FZ 9.12162
57 2JB2 FAD 9.45946
58 2JB2 PHE 9.45946
59 5MDR NAG NAG NAG NAG NAG NAG 9.45946
60 1LVW TYD 9.49153
61 3WGC PLG 9.7973
62 3Q9T FAY 10.1351
63 3AD8 NAD 11.1111
64 3FRK TQP 11.1486
65 3KPX CZH 11.4865
66 1GSA ADP 11.8243
67 2C2A ADP 12.0155
68 2C5S AMP 12.5
69 4EHU ANP 13.0435
70 6FKW PQQ 14.527
71 3RT4 LP5 15.7895
72 3NRZ MTE 20.122
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