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Receptor
PDB id Resolution Class Description Source Keywords
1H0C 2.5 Å EC: 2.6.1.44 THE CRYSTAL STRUCTURE OF HUMAN ALANINE:GLYOXYLATE AMINOTRANSFERASE HOMO SAPIENS AMINOTRANSFERASE PYRIDOXAL PHOSPHATE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF ALANINE:GLYOXYLATE AMINOTRANSFERASE AND THE RELATIONSHIP BETWEEN GENOTYPE AND ENZYMATIC PHENOTYPE IN PRIMARY HYPEROXALURIA TYPE 1. J.MOL.BIOL. V. 331 643 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AOA A:1392;
Valid;
none;
submit data
91.066 C2 H5 N O3 C(C(=...
GOL A:1393;
A:1394;
A:1395;
A:1396;
A:1397;
A:1398;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
PLP A:1391;
Invalid;
none;
submit data
247.142 C8 H10 N O6 P Cc1c(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1H0C 2.5 Å EC: 2.6.1.44 THE CRYSTAL STRUCTURE OF HUMAN ALANINE:GLYOXYLATE AMINOTRANSFERASE HOMO SAPIENS AMINOTRANSFERASE PYRIDOXAL PHOSPHATE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF ALANINE:GLYOXYLATE AMINOTRANSFERASE AND THE RELATIONSHIP BETWEEN GENOTYPE AND ENZYMATIC PHENOTYPE IN PRIMARY HYPEROXALURIA TYPE 1. J.MOL.BIOL. V. 331 643 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1H0C - AOA C2 H5 N O3 C(C(=O)O)O....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1H0C - AOA C2 H5 N O3 C(C(=O)O)O....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1H0C - AOA C2 H5 N O3 C(C(=O)O)O....
2 2HUI - GLV C2 H2 O3 C(=O)C(=O)....
3 2HUU - ALA C3 H7 N O2 C[C@@H](C(....
4 1VJO - PLP C8 H10 N O6 P Cc1c(c(c(c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AOA; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 AOA 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1H0C; Ligand: AOA; Similar sites found with APoc: 4
This union binding pocket(no: 1) in the query (biounit: 1h0c.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 6GEW SFG 1.78571
2 6GEW SAH 1.78571
3 5CPS GLC GLC GLC GLC GLC GLC GLC GLC GLC 2.04082
4 4GKV NAD 4.7619
Pocket No.: 2; Query (leader) PDB : 1H0C; Ligand: AOA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1h0c.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
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