Receptor
PDB id Resolution Class Description Source Keywords
1GPM 2.2 Å EC: 6.3.5.2 ESCHERICHIA COLI GMP SYNTHETASE COMPLEXED WITH AMP AND PYROP ESCHERICHIA COLI CLASS I GLUTAMINE AMIDOTRANSFERASE N-TYPE ATP PYROPHOSPHATATRANSFERASE (GLUTAMINE AMIDOTRANSFERASE)
Ref.: THE CRYSTAL STRUCTURE OF GMP SYNTHETASE REVEALS A N CATALYTIC TRIAD AND IS A STRUCTURAL PARADIGM FOR TW FAMILIES. NAT.STRUCT.BIOL. V. 3 74 1996
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AMP A:527;
B:527;
C:527;
D:527;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
347.221 C10 H14 N5 O7 P c1nc(...
CIT A:529;
B:529;
C:529;
D:529;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
192.124 C6 H8 O7 C(C(=...
MG B:530;
C:530;
D:530;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
PO4 A:528;
B:528;
C:528;
D:528;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
POP A:526;
B:526;
C:526;
D:526;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
175.959 H2 O7 P2 O[P@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1GPM 2.2 Å EC: 6.3.5.2 ESCHERICHIA COLI GMP SYNTHETASE COMPLEXED WITH AMP AND PYROP ESCHERICHIA COLI CLASS I GLUTAMINE AMIDOTRANSFERASE N-TYPE ATP PYROPHOSPHATATRANSFERASE (GLUTAMINE AMIDOTRANSFERASE)
Ref.: THE CRYSTAL STRUCTURE OF GMP SYNTHETASE REVEALS A N CATALYTIC TRIAD AND IS A STRUCTURAL PARADIGM FOR TW FAMILIES. NAT.STRUCT.BIOL. V. 3 74 1996
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GPM - CIT C6 H8 O7 C(C(=O)O)C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GPM - CIT C6 H8 O7 C(C(=O)O)C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1GPM - CIT C6 H8 O7 C(C(=O)O)C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AMP; Similar ligands found: 382
No: Ligand ECFP6 Tc MDL keys Tc
1 AMP 1 1
2 A 1 1
3 A2D 0.833333 0.943662
4 ABM 0.833333 0.943662
5 ADP 0.823529 0.971429
6 AMP MG 0.818182 0.916667
7 A12 0.808824 0.931507
8 AP2 0.808824 0.931507
9 BA3 0.808824 0.943662
10 SRA 0.80303 0.944444
11 AP5 0.797101 0.943662
12 B4P 0.797101 0.943662
13 ATP 0.788732 0.971429
14 AN2 0.785714 0.957747
15 APC 0.777778 0.931507
16 AQP 0.777778 0.971429
17 5FA 0.777778 0.971429
18 ADX 0.774648 0.848101
19 CA0 0.774648 0.917808
20 M33 0.774648 0.930556
21 AU1 0.774648 0.944444
22 ACP 0.763889 0.944444
23 50T 0.763889 0.957747
24 25A 0.75641 0.971429
25 AR6 0.753425 0.943662
26 APR 0.753425 0.943662
27 PRX 0.753425 0.917808
28 ADP MG 0.75 0.90411
29 TAT 0.746667 0.931507
30 ACQ 0.746667 0.944444
31 RBY 0.743243 0.905405
32 SAP 0.743243 0.918919
33 AGS 0.743243 0.918919
34 ADV 0.743243 0.905405
35 AD9 0.743243 0.944444
36 BEF ADP 0.739726 0.88
37 ADP BEF 0.739726 0.88
38 ANP 0.723684 0.944444
39 ADP PO3 0.72 0.942857
40 5AL 0.714286 0.930556
41 SON 0.712329 0.931507
42 ATP MG 0.710526 0.90411
43 ADN 0.709677 0.842857
44 XYA 0.709677 0.842857
45 RAB 0.709677 0.842857
46 ATF 0.705128 0.931507
47 GAP 0.701299 0.891892
48 A22 0.7 0.957747
49 SRP 0.696203 0.905405
50 7D5 0.691176 0.902778
51 A3P 0.684932 0.971014
52 A2P 0.684932 0.956522
53 ALF ADP 0.683544 0.868421
54 ADP ALF 0.683544 0.868421
55 ADQ 0.682927 0.917808
56 MAP 0.679012 0.918919
57 ANP MG 0.675 0.893333
58 ADP VO4 0.675 0.930556
59 VO4 ADP 0.675 0.930556
60 5SV 0.670732 0.87013
61 OOB 0.670732 0.930556
62 8QN 0.670732 0.930556
63 PTJ 0.670588 0.894737
64 AOC 0.666667 0.84507
65 4AD 0.662651 0.893333
66 A1R 0.662651 0.881579
67 AMO 0.662651 0.905405
68 PAJ 0.662651 0.858974
69 5N5 0.661538 0.816901
70 DAL AMP 0.658537 0.90411
71 IMO 0.657534 0.928571
72 DLL 0.654762 0.930556
73 AHX 0.654762 0.87013
74 00A 0.654762 0.881579
75 5AS 0.653333 0.776471
76 5CD 0.651515 0.828571
77 A4D 0.651515 0.816901
78 3UK 0.647059 0.917808
79 ADP BMA 0.647059 0.891892
80 OAD 0.647059 0.917808
81 25L 0.643678 0.957747
82 PR8 0.639535 0.848101
83 WAQ 0.639535 0.881579
84 LAD 0.639535 0.858974
85 DTA 0.637681 0.808219
86 V3L 0.6375 0.971429
87 3DH 0.633803 0.794521
88 BIS 0.632184 0.906667
89 TXA 0.632184 0.905405
90 FYA 0.632184 0.930556
91 ME8 0.632184 0.8375
92 1ZZ 0.632184 0.8375
93 3OD 0.632184 0.917808
94 NB8 0.632184 0.87013
95 MTA 0.628571 0.794521
96 3AM 0.625 0.956522
97 EP4 0.623188 0.773333
98 A A 0.62069 0.971429
99 9SN 0.617977 0.87013
100 M2T 0.614286 0.753247
101 JB6 0.613636 0.881579
102 YAP 0.611111 0.893333
103 FA5 0.611111 0.905405
104 MYR AMP 0.606742 0.814815
105 G5A 0.604938 0.776471
106 XAH 0.604396 0.8375
107 4UV 0.597826 0.893333
108 71V 0.597403 0.906667
109 ATP A A A 0.593407 0.929577
110 PAP 0.592593 0.957143
111 G3A 0.591398 0.894737
112 2AM 0.589041 0.942857
113 5X8 0.5875 0.783784
114 TYR AMP 0.586957 0.88
115 6RE 0.586667 0.779221
116 6C6 0.585366 0.905405
117 4UU 0.585106 0.893333
118 G5P 0.585106 0.894737
119 AFH 0.585106 0.858974
120 7D3 0.584416 0.878378
121 A5A 0.583333 0.804878
122 TSB 0.581395 0.795181
123 AMP DBH 0.580645 0.891892
124 2A5 0.580247 0.891892
125 DSH 0.578947 0.74359
126 TAD 0.578947 0.858974
127 GTA 0.578947 0.860759
128 6IA 0.578313 0.858974
129 SSA 0.576471 0.776471
130 C2R 0.575342 0.876712
131 AMZ 0.575342 0.888889
132 7D4 0.575 0.878378
133 PGS 0.575 0.857143
134 ZAS 0.573333 0.786667
135 ATR 0.573171 0.942857
136 LAQ 0.572917 0.8375
137 PPS 0.571429 0.848101
138 AAM 0.571429 1
139 AIR 0.571429 0.927536
140 J7C 0.571429 0.789474
141 A3N 0.571429 0.783784
142 54H 0.569767 0.785714
143 VMS 0.569767 0.785714
144 52H 0.569767 0.776471
145 7MD 0.568421 0.8375
146 AR6 AR6 0.568421 0.916667
147 48N 0.56701 0.87013
148 YLP 0.56701 0.817073
149 OVE 0.565789 0.90411
150 UPA 0.565657 0.881579
151 2SA 0.564706 0.905405
152 S4M 0.564103 0.682353
153 53H 0.563218 0.776471
154 5CA 0.563218 0.776471
155 4UW 0.561224 0.858974
156 NAI 0.561224 0.881579
157 TXD 0.561224 0.881579
158 6V0 0.561224 0.87013
159 UP5 0.561224 0.893333
160 DND 0.561224 0.905405
161 NXX 0.561224 0.905405
162 NAX 0.561224 0.848101
163 NIA 0.56 0.820513
164 D5M 0.558442 0.902778
165 DA 0.558442 0.902778
166 MAO 0.556962 0.777778
167 AHZ 0.556701 0.814815
168 ARG AMP 0.556701 0.82716
169 ITT 0.555556 0.915493
170 TXE 0.555556 0.881579
171 TYM 0.555556 0.905405
172 OMR 0.555556 0.82716
173 5AD 0.552239 0.768116
174 A2R 0.551724 0.957747
175 LPA AMP 0.55102 0.814815
176 DSZ 0.550562 0.776471
177 LSS 0.550562 0.758621
178 NSS 0.550562 0.776471
179 YLB 0.55 0.817073
180 YLC 0.55 0.8375
181 4TC 0.55 0.87013
182 AP0 0.55 0.87013
183 P5A 0.549451 0.741573
184 139 0.54902 0.848101
185 A4P 0.544554 0.819277
186 NVA LMS 0.544444 0.758621
187 GJV 0.544304 0.769231
188 7D7 0.544118 0.763889
189 A7D 0.54321 0.797297
190 ALF ADP 3PG 0.54 0.835443
191 LA8 ALF 3PG 0.54 0.835443
192 AF3 ADP 3PG 0.54 0.835443
193 6K6 0.539326 0.957143
194 IOT 0.539216 0.829268
195 LEU LMS 0.538462 0.758621
196 A3G 0.538462 0.797297
197 A5D 0.535714 0.808219
198 7MC 0.534653 0.817073
199 T5A 0.533981 0.817073
200 YLA 0.533981 0.817073
201 ADJ 0.533981 0.82716
202 KAA 0.532609 0.75
203 GSU 0.532609 0.776471
204 7RA 0.531646 0.985507
205 SFG 0.53012 0.77027
206 SAH 0.529412 0.763158
207 AYB 0.528846 0.807229
208 CNA 0.528846 0.905405
209 N6P 0.527473 0.942029
210 8BR 0.525 0.931507
211 Y3J 0.521127 0.746479
212 YSA 0.520833 0.776471
213 7RP 0.518987 0.955882
214 G A A A 0.518868 0.87013
215 COD 0.518868 0.788235
216 BTX 0.518868 0.839506
217 NAD 0.518868 0.930556
218 MHZ 0.518072 0.714286
219 SA8 0.517647 0.725
220 6AD 0.517241 0.883117
221 DZD 0.514019 0.858974
222 BT5 0.514019 0.829268
223 RMB 0.5125 0.898551
224 SAI 0.511628 0.753247
225 AV2 0.511364 0.890411
226 NAD IBO 0.509434 0.868421
227 A3D 0.509259 0.917808
228 A3S 0.506024 0.808219
229 SAM 0.505747 0.707317
230 3AT 0.505747 0.943662
231 SMM 0.505618 0.702381
232 NA7 0.505376 0.931507
233 4TA 0.504673 0.804878
234 5GP 0.5 0.905405
235 EEM 0.5 0.707317
236 NEC 0.5 0.743243
237 AAT 0.5 0.725
238 G 0.5 0.905405
239 YLY 0.495495 0.807229
240 M24 0.495495 0.848101
241 7C5 0.494949 0.815789
242 DAT 0.494118 0.878378
243 A3T 0.494118 0.819444
244 FAI 0.493827 0.888889
245 P2P 0.493827 0.928571
246 1RB 0.493671 0.911765
247 NAE 0.491071 0.893333
248 NAJ PZO 0.490909 0.846154
249 TM1 0.489583 0.771084
250 A6D 0.489362 0.740741
251 PO4 PO4 A A A A PO4 0.489362 0.901408
252 A A A 0.489362 0.90411
253 S7M 0.488889 0.707317
254 DTP 0.488636 0.878378
255 101 0.4875 0.902778
256 RBZ 0.4875 0.873239
257 EAD 0.486957 0.848101
258 NAQ 0.486726 0.87013
259 U A G G 0.486239 0.881579
260 4YB 0.485149 0.758621
261 NDE 0.483051 0.931507
262 N0B 0.482456 0.817073
263 ZID 0.482456 0.917808
264 WSA 0.480769 0.785714
265 RGT 0.479592 0.931507
266 ARU 0.478723 0.835443
267 GGZ 0.478261 0.8
268 JLN 0.47561 0.863014
269 ANZ 0.475248 0.820513
270 ACK 0.475 0.885714
271 QQY 0.475 0.837838
272 NAJ PYZ 0.473684 0.848101
273 S8M 0.473118 0.779221
274 GEK 0.473118 0.734177
275 AVV 0.473118 0.87013
276 3AD 0.472973 0.828571
277 A U 0.471698 0.868421
278 P1H 0.470588 0.82716
279 AMP NAD 0.469565 0.88
280 0UM 0.468085 0.716049
281 RVP 0.467532 0.847222
282 649 0.466667 0.741573
283 Z5A 0.465517 0.776471
284 PMO 0.464286 0.873239
285 SXZ 0.463918 0.707317
286 62X 0.463158 0.682353
287 QQX 0.4625 0.826667
288 2VA 0.45977 0.797297
289 IMP 0.458824 0.90411
290 K15 0.458333 0.698795
291 CC5 0.458333 0.84058
292 AS 0.457831 0.855263
293 DDS 0.455556 0.851351
294 V1N 0.455446 0.943662
295 NJP 0.454545 0.918919
296 93A 0.453488 0.804878
297 G7M 0.453488 0.87013
298 7DD 0.453488 0.957143
299 3D1 0.453333 0.77027
300 3L1 0.453333 0.77027
301 NDC 0.45082 0.87013
302 FB0 0.45082 0.781609
303 0WD 0.45045 0.894737
304 26A 0.447368 0.76
305 2FA 0.447368 0.810811
306 CMP 0.447059 0.927536
307 2BA 0.447059 0.914286
308 D3Y 0.446809 0.786667
309 SO8 0.444444 0.786667
310 APU 0.444444 0.893333
311 VRT 0.444444 0.766234
312 KB1 0.444444 0.716049
313 FDA 0.443548 0.809524
314 PUA 0.443478 0.858974
315 ODP 0.441441 0.883117
316 6FA 0.44 0.817073
317 RP1 0.439024 0.864865
318 SP1 0.439024 0.864865
319 103 0.439024 0.861111
320 3NZ 0.438776 0.779221
321 7DT 0.438202 0.957143
322 U G A 0.436508 0.8375
323 NDP 0.436364 0.894737
324 NPW 0.436364 0.860759
325 MTP 0.434211 0.727273
326 NVA 2AD 0.433333 0.74026
327 FAD 0.433071 0.82716
328 SFD 0.433071 0.712766
329 FAS 0.433071 0.82716
330 TXP 0.432432 0.894737
331 IRN 0.432432 0.867647
332 NZQ 0.432432 0.883117
333 ZZB 0.432432 0.792683
334 FNK 0.430769 0.781609
335 62F 0.430769 0.8375
336 128 0.429907 0.752941
337 PLP AAD 0.429825 0.758621
338 PAX 0.428571 0.82716
339 6MD 0.428571 0.805556
340 1DA 0.428571 0.842857
341 SLU 0.426087 0.767442
342 XNP 0.424779 0.848101
343 12D 0.424528 0.761905
344 5F1 0.423077 0.72973
345 ETB 0.422414 0.809524
346 DCA 0.422414 0.8
347 WMP 0.421053 0.864865
348 GUO 0.421053 0.864865
349 FAY 0.416667 0.8375
350 38Y 0.415929 0.804878
351 5J9 0.415842 0.728395
352 NAD BBN 0.415385 0.817073
353 0T1 0.415254 0.8
354 COA 0.415254 0.8
355 KH3 0.415094 0.690476
356 FMP 0.413793 0.871429
357 U A C C 0.413793 0.857143
358 N01 0.413793 0.90411
359 RFL 0.413534 0.797619
360 NMN AMP PO4 0.412281 0.868421
361 NAD CJ3 0.409091 0.788235
362 GDP 0.408602 0.893333
363 GP2 0.408602 0.858974
364 NAP 0.408333 0.944444
365 NOC 0.407895 0.760563
366 CNV FAD 0.407407 0.770115
367 2ER 0.405941 0.831169
368 1PR 0.405941 0.820513
369 P5F 0.405797 0.8
370 TAP 0.404959 0.906667
371 CAO 0.404959 0.772727
372 AMX 0.404959 0.809524
373 COS 0.404959 0.781609
374 30N 0.404959 0.731183
375 XMP 0.402299 0.891892
376 G2P 0.402062 0.858974
377 APC G U 0.401709 0.833333
378 U A A U 0.401639 0.906667
379 CMX 0.401639 0.8
380 SCO 0.401639 0.8
381 NA0 0.401639 0.931507
382 F2N 0.4 0.790698
Ligand no: 2; Ligand: CIT; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 CIT 1 1
2 HCA 0.576923 0.884615
3 MAH 0.44 0.807692
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1GPM; Ligand: CIT; Similar sites found: 78
This union binding pocket(no: 1) in the query (biounit: 1gpm.bio1) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3JDW ORN 0.02268 0.40056 1.18203
2 2VVM FAD 0.02093 0.4311 1.21212
3 2XIQ MLC 0.03294 0.40914 1.52381
4 4P8K 38C 0.04571 0.41704 1.66667
5 1N4W FAD 0.02061 0.43245 1.78571
6 3NTD FAD 0.04907 0.40695 1.90476
7 1SAY PYR 0.0437 0.40697 1.93906
8 4Z24 FAD 0.04253 0.41423 2.09524
9 3LXN MI1 0.01494 0.4146 2.20126
10 3ZYR NAG NAG BMA MAN MAN NAG NAG 0.02178 0.40661 2.29885
11 4USQ FAD 0.01159 0.43893 2.49307
12 5JFL NAD 0.01431 0.42831 2.67176
13 2WQQ CSF 0.02831 0.40071 2.74914
14 1LBZ FBP 0.02997 0.40249 2.77778
15 2R4J 13P 0.01615 0.44589 2.79441
16 1BXG NAD 0.02855 0.40939 2.80899
17 4GKV NAD 0.02741 0.41839 2.97619
18 1MO9 FAD 0.02961 0.44362 3.05927
19 1MO9 KPC 0.03027 0.44352 3.05927
20 3CIF NAD 0.0441 0.40167 3.06407
21 1QZR ANP 0.03697 0.40098 3.11005
22 4IO2 GLU 0.01703 0.40484 3.22581
23 1XRO LEU 0.03807 0.41055 3.41297
24 1U7T NAD 0.0437 0.40069 3.44828
25 1RP0 AHZ 0.01801 0.42529 3.52113
26 3H8C NSZ 0.01053 0.43706 3.63636
27 1T26 NAI 0.03409 0.4202 3.72671
28 1GR0 NAD 0.02581 0.41955 3.81471
29 2P3V SRT 0.003591 0.41566 3.90625
30 1ME8 RVP 0.03029 0.41716 3.97614
31 2RGH FAD 0.02914 0.42168 4
32 1V8B NAD 0.008497 0.44927 4.17537
33 4IVG ANP 0.02966 0.40362 4.19048
34 2X05 X05 0.02011 0.40147 4.19048
35 5J6Y BGC 0.01063 0.41143 4.25532
36 5J6Y GLC 0.01063 0.41143 4.25532
37 4MSG 2C6 0.02466 0.42186 4.60829
38 4JEM C5P 0.02664 0.40282 4.70588
39 1V59 FAD 0.0145 0.44357 4.7619
40 2OD9 A1R NCA 0.03376 0.40862 4.87013
41 3QUR FM4 0.03853 0.4083 4.8951
42 5UIU 8CG 0.04437 0.40071 4.95356
43 1TDF FAD 0.03576 0.42127 5.06329
44 1REQ DCA 0.03822 0.41693 5.33333
45 1KOJ PAN 0.02657 0.40357 5.52381
46 5JCM NAD 0.03224 0.43535 5.54324
47 5JCM FAD 0.03152 0.43535 5.54324
48 5JCM ISD 0.03224 0.43535 5.54324
49 2X3F APC 0.04204 0.40103 5.61404
50 3GD4 FAD 0.003792 0.46881 5.67515
51 4BV6 FAD 0.005836 0.46205 5.67951
52 1L3I SAH 0.03005 0.40748 5.72917
53 1IY8 NAD 0.04521 0.40331 5.99251
54 1DL5 SAH 0.03555 0.40438 5.99369
55 1GV0 NAD 0.03766 0.40623 6.12903
56 2D5A COA 0.03035 0.40329 6.25
57 5UWP GNP 0.03175 0.40751 6.29371
58 5UWS GNP 0.03608 0.40441 6.29371
59 1VBO MAN MAN MAN 0.006949 0.41435 6.71141
60 1GUZ NAD 0.03291 0.40818 7.09677
61 1VCO GLN 0.001415 0.44839 7.2381
62 3S5W NAP 0.01897 0.40514 7.5594
63 1WHT BZS 0.002836 0.43 7.8125
64 3OND ADN 0.04818 0.4158 7.9918
65 1EB1 ZAL PRO MMO 0.0482 0.40125 8.17121
66 1QPR PPC 0.02786 0.40352 8.4507
67 2P53 NNG 0.02568 0.40296 8.63874
68 1N07 ADP 0.02588 0.40157 9.20245
69 4ZA2 NAD 0.02343 0.41696 9.88142
70 1U9Q 186 0.01766 0.40769 10.2326
71 2IMP NAI 0.04797 0.4057 11.2735
72 1J0D 5PA 0.03586 0.40392 12.0235
73 1D4D FAD 0.03375 0.42091 12.5714
74 4YEF 4CQ 0.02845 0.41457 13.4831
75 1IDA 0PO 0.04998 0.4055 14.1414
76 4L8F MTX 0.005961 0.40533 17.6282
77 5L9Z GUX 0.02888 0.40389 20.7792
78 2NV2 GLN 0.01403 0.40079 35.2941
Pocket No.: 2; Query (leader) PDB : 1GPM; Ligand: CIT; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1gpm.bio1) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1GPM; Ligand: AMP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1gpm.bio1) has 9 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1GPM; Ligand: AMP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1gpm.bio1) has 9 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1GPM; Ligand: AMP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1gpm.bio1) has 9 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1GPM; Ligand: CIT; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1gpm.bio1) has 12 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1GPM; Ligand: AMP; Similar sites found: 255
This union binding pocket(no: 7) in the query (biounit: 1gpm.bio1) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1JE1 GMP 0.04335 0.40141 None
2 2YYJ FAD 0.008112 0.44409 1.0395
3 1MDB AMP DBH 0.0185 0.41925 1.33333
4 3BJE URA 0.007186 0.40705 1.43266
5 5W4W 9WG 0.007079 0.44698 1.51057
6 4XVX P6G FDA 0.003977 0.46795 1.54242
7 1LYX PGA 0.01419 0.40455 1.6129
8 2X4Z X4Z 0.03309 0.41518 1.68919
9 1G51 AMP 0.0009348 0.45589 1.71429
10 5N9X 8QN 0.01324 0.42335 1.71429
11 2WEI VGG 0.01579 0.41265 1.74216
12 1NW4 IMH 0.01326 0.41471 1.81159
13 3SSO SAH 0.006018 0.44482 1.90931
14 2OQ2 A3P 0.0008016 0.48455 1.91571
15 4LOO SB4 0.004402 0.43297 1.93906
16 3E7O 35F 0.01412 0.41318 1.94444
17 3OII SAH 0.01353 0.41834 1.97628
18 3MJE NDP 0.009273 0.43288 2.01613
19 2ZKJ ADP 0.002687 0.48402 2.03046
20 4NM5 ADP 0.01847 0.42387 2.12202
21 4MV1 ADP 0.01871 0.42651 2.13675
22 3ZRM ZRM 0.02862 0.40531 2.15633
23 1HV9 COA 0.02023 0.43261 2.19298
24 4KCF FMN 0.004191 0.43638 2.20264
25 4TWP AXI 0.03125 0.41528 2.21402
26 5BVE 4VG 0.004384 0.47822 2.21607
27 2UYQ SAM 0.008011 0.40241 2.25806
28 1N9G NAP 0.03607 0.40217 2.33161
29 5AFN L0B 0.01662 0.42773 2.41546
30 3E9I XAH 0.001646 0.46942 2.43408
31 2RKV ZBA 0.01004 0.43129 2.43902
32 3V8S 0HD 0.02843 0.40529 2.43902
33 1CM8 ANP 0.03456 0.40155 2.45232
34 5FAL COA 0.04962 0.41068 2.45536
35 5FAL SKT 0.04962 0.41068 2.45536
36 4FG8 ATP 0.0194 0.40471 2.53968
37 5LRT ADP 0.01995 0.41358 2.55906
38 5H2U 1N1 0.002647 0.44056 2.62172
39 2CWH PYC 0.005509 0.45315 2.62391
40 2CWH NDP 0.004523 0.45315 2.62391
41 2D1S SLU 0.01135 0.43235 2.66667
42 4WOE ADP 0.03076 0.40717 2.66667
43 4B2Z P5S 0.03136 0.40851 2.67857
44 5DBX ANP 0.02041 0.40501 2.7439
45 2H8H H8H 0.02 0.41493 2.85714
46 2ZA5 2FF 0.02914 0.40242 2.85714
47 5C5H 4YB 0.02056 0.40753 2.86976
48 1UTJ ABN 0.005719 0.43877 2.89256
49 4Y93 746 0.03765 0.40751 2.9148
50 3WCZ NAP 0.03784 0.40839 2.92208
51 3WV1 WHH 0.03198 0.41778 2.92398
52 1VJY 460 0.005338 0.43991 2.9703
53 5ULP KB1 0.02956 0.40366 2.98507
54 4ANW O92 0.02896 0.41408 3.04762
55 1YP4 ADP 0.01483 0.41203 3.04762
56 1CT9 AMP 0.007141 0.40801 3.04762
57 3KRR DQX 0.02817 0.44022 3.05085
58 2WK9 PLP 0.01677 0.43895 3.08483
59 5LYH 7B8 0.006044 0.45082 3.10881
60 5EOB 5QQ 0.0455 0.41501 3.1348
61 4DE9 VTP 0.03618 0.41272 3.14685
62 3WYJ H78 0.0008177 0.52638 3.16206
63 5TCI MLI 0.008652 0.40827 3.26087
64 5LPZ ADP 0.02954 0.40321 3.31325
65 1Y57 MPZ 0.04376 0.40199 3.31858
66 1M15 ARG 0.03864 0.4123 3.36134
67 1M15 ADP 0.03864 0.4123 3.36134
68 1GVE NAP 0.02298 0.40012 3.36391
69 2C5S AMP 0.0001025 0.43286 3.38983
70 3THR C2F 0.003687 0.4362 3.41297
71 1J39 UPG 0.02795 0.40885 3.4188
72 4L2I FAD 0.0001909 0.52459 3.42205
73 4L2I NAD 0.0002875 0.52459 3.42205
74 1I1E DM2 0.004962 0.42219 3.42857
75 4Z9D NAD 0.007935 0.40889 3.42857
76 2Y4N DLL 0.02961 0.40263 3.43249
77 1X54 4AD 0.01621 0.40732 3.45622
78 4QAR ADE 0.01854 0.40592 3.48259
79 5X8G S0N 0.03469 0.40779 3.50515
80 4RRG A3T 0.008703 0.42327 3.5461
81 3ZF8 GDP 0.001188 0.45548 3.60656
82 3O7B SAH 0.004262 0.44998 3.61905
83 4AGQ P96 0.01557 0.41804 3.65297
84 4ZSD 7I6 0.02201 0.40097 3.65854
85 5LPB ADP 0.02107 0.40408 3.71622
86 5L9O GOP 0.005307 0.43685 3.73134
87 4ITH RCM 0.007788 0.42917 3.7415
88 4X28 FDA 0.01772 0.42444 3.75
89 3DLG GWE 0.01878 0.43439 3.86364
90 1ZTH ADP 0.02979 0.40386 3.87597
91 1ZP9 ATP 0.03583 0.40347 3.87597
92 4LUS TCE 0.005532 0.4294 3.8961
93 1RY2 AMP 0.01204 0.41857 3.92157
94 2VN9 GVD 0.01141 0.41267 3.98671
95 3ACL 3F1 0.01004 0.41875 4.05405
96 1BC5 ACE ASN TRP GLU THR PHE 0.007036 0.4139 4.08922
97 1BC5 SAH 0.04127 0.40203 4.08922
98 4IGQ THR M3L GLN 0.02353 0.40745 4.16667
99 2QIA U20 0.01064 0.44943 4.19847
100 1L6O SER LEU LYS LEU MET THR THR VAL 0.008263 0.42164 4.21053
101 1K4M NAD 0.02723 0.41524 4.22535
102 5N5D SAM 0.01367 0.40246 4.42478
103 2I7N ACO 0.009629 0.4235 4.44444
104 4JWH SAH 0.002131 0.4721 4.47284
105 2VH6 GSV 0.0003254 0.52407 4.47761
106 2PYW ADP 0.03163 0.40865 4.52381
107 3G6K FAD 0.003104 0.46358 4.54545
108 3G6K POP 0.002804 0.46358 4.54545
109 4HIA FMN 0.0151 0.42731 4.54545
110 2BSA NAP 0.0259 0.41935 4.62046
111 2BSA FAD 0.02522 0.41935 4.62046
112 5A5W GUO 0.04889 0.40443 4.74308
113 1NB9 ADP 0.003471 0.4602 4.7619
114 1NB9 RBF 0.003471 0.4602 4.7619
115 4A1O JLN 0.005141 0.4351 4.78011
116 4EN4 GT1 0.01873 0.43083 4.80769
117 4EN4 ATP 0.01873 0.43083 4.80769
118 4EN4 GT0 0.01873 0.43083 4.80769
119 3PFD FDA 0.04628 0.41072 4.83461
120 4B0T ADP 0.009118 0.41518 4.86815
121 4MCC 21X 0.007999 0.43095 4.87805
122 1SQA UI1 0.005337 0.47052 4.89796
123 1NNS ASP 0.02313 0.40292 4.90798
124 2E2R 2OH 0.01013 0.4299 4.91803
125 5ECP ATP 0.01473 0.42525 4.93274
126 5ECP JAA 0.04541 0.40938 4.93274
127 5ECP MET 0.04541 0.40938 4.93274
128 2AC7 ADN 0.009949 0.42108 4.95238
129 2Y4O DLL 0.004243 0.44225 4.96614
130 1P9P SAH 0.001442 0.48172 4.98084
131 3UWV 2PG 0.01165 0.42208 4.98084
132 2GU8 796 0.02018 0.44225 5.04451
133 2YKL NLD 0.01279 0.40776 5.09259
134 4J7H TLO 0.004325 0.45398 5.09554
135 3JU6 ANP 0.01555 0.40292 5.13514
136 3IES M24 0.02592 0.41359 5.14286
137 3BL6 FMC 0.0188 0.40024 5.21739
138 3K56 IS3 0.001936 0.45379 5.26316
139 1O5E 132 0.006882 0.43084 5.26316
140 5MSD AMP 0.004337 0.44972 5.33333
141 5MSD BEZ 0.005523 0.44972 5.33333
142 5APG EEM 0.01396 0.41514 5.40541
143 9LDT NAD 0.04408 0.40605 5.42169
144 3PD2 A3S 0.01869 0.43287 5.44218
145 2IV2 MGD 0.04766 0.40587 5.52381
146 5ALC TIQ 0.03214 0.40615 5.55556
147 3G5D 1N1 0.0115 0.45345 5.59441
148 1ZGA SAH 0.007016 0.42626 5.60224
149 4OLT GCS GCS GCS GCS GCS GCS 0.02576 0.41634 5.64516
150 3KRB NAP 0.01262 0.42117 5.68862
151 4WKB TDI 0.03018 0.4045 5.7377
152 3A5Z KAA 0.04155 0.40271 5.75916
153 1Q19 APC 0.0001899 0.50108 5.76541
154 5A7Y SAH 0.005636 0.42609 5.76923
155 5FM0 WAQ 0.02556 0.42492 5.76923
156 1FL2 FAD 0.04203 0.40142 5.80645
157 1WXI AMP 0.000002547 0.66537 5.81818
158 4XV1 904 0.01021 0.44063 5.82192
159 5I7A 68Q 0.01818 0.4087 5.82822
160 4USI ATP 0.007326 0.43597 5.84416
161 2J9D AMP 0.000763 0.48162 5.88235
162 2J9D ADP 0.018 0.40585 5.88235
163 2J9C ATP 0.02381 0.40549 5.88235
164 5EW9 5VC 0.003477 0.49834 5.90406
165 2W5P CL8 0.0002489 0.48983 6.04027
166 2EW5 Y12 0.02393 0.40137 6.07735
167 4CQE CQE 0.04127 0.40684 6.11511
168 5AHW CMP 0.0003574 0.50679 6.12245
169 1OJZ NAD 0.01079 0.4227 6.13208
170 3SXF BK5 0.00772 0.44653 6.19835
171 5L83 ASP TRP GLU ILE VAL 0.004848 0.43676 6.25
172 2DRC MTX 0.009611 0.49391 6.28931
173 4DSU BZI 0.006374 0.41558 6.34921
174 3EFS BTN 0.01074 0.41909 6.43777
175 1JQI FAD 0.03554 0.41164 6.4433
176 1M5B BN1 0.02766 0.44854 6.46388
177 1O44 852 0.03572 0.40876 6.48148
178 4M73 SAH 0.02544 0.42025 6.52819
179 3BMN NAP 0.04599 0.40139 6.59722
180 2P3T 993 0.009984 0.42962 6.86695
181 1KQN NAD 0.01965 0.41132 7.16846
182 5XDT MB3 0.0009738 0.49833 7.2381
183 2C91 NAP 0.00221 0.46499 7.2381
184 5XDT GDP 0.006796 0.44087 7.2381
185 1BH2 GSP 0.04004 0.40551 7.30159
186 5COU ATP 0.004969 0.43987 7.35294
187 1YKI NFZ 0.03194 0.41839 7.37327
188 1YKI FMN 0.02823 0.41839 7.37327
189 5FBN 5WF 0.04984 0.40602 7.38007
190 2GQT FAD 0.03712 0.4181 7.46269
191 5J75 6GQ 0.008374 0.4228 7.57576
192 1PQ7 ARG 0.0006029 0.48819 7.58929
193 5M6N 7H9 0.009478 0.40731 7.62712
194 2PZ8 APC 0.0000008745 0.65612 7.74648
195 4RZ3 ADP 0.02343 0.40145 7.79661
196 1KQB FMN 0.01428 0.41839 7.8341
197 1KQB BEZ 0.02367 0.41081 7.8341
198 2WEL K88 0.01302 0.40316 8
199 4RT1 C2E 0.007185 0.42577 8.03571
200 2G30 ALA ALA PHE 0.001161 0.4199 8.13953
201 5CJ3 52G 0.04602 0.40038 8.14815
202 3JQ3 ADP 0.01752 0.40684 8.46994
203 5F7J ADE 0.003912 0.44111 8.75
204 2BP1 NDP 0.001924 0.46895 8.7619
205 4YUW S4M 0.0139 0.46757 8.88158
206 4YUW 4JU 0.0141 0.46757 8.88158
207 1N07 ADP 0.0001953 0.52371 9.20245
208 1N07 FMN 0.0004431 0.52181 9.20245
209 3A4X NAG NAG NAG NDG 0.02605 0.41054 9.32476
210 5LLT DND 0.01888 0.42719 9.38967
211 3HGM ATP 0.0003064 0.50982 9.52381
212 4JAL SAH 0.00198 0.46396 9.58084
213 4IPH 1FJ 0.03528 0.40026 9.7561
214 1S4M LUM 0.0003827 0.51848 9.89761
215 3CM2 X23 0.00602 0.41828 10
216 3W8X FAD 0.04779 0.40765 10.0427
217 1CLU DBG 0.005869 0.46334 10.241
218 2V3V MGD 0.04688 0.42628 10.8571
219 4L3L 5FI 0.02775 0.41485 11.1842
220 3L9R L9R 0.0425 0.40855 11.3074
221 3L9R L9Q 0.03942 0.40687 11.3074
222 3AIA SAM 0.005084 0.43529 11.3744
223 5AGR A52 0.02529 0.40024 11.6379
224 3OQJ 3CX 0.0003594 0.40567 11.6732
225 5TWJ SAM 0.004063 0.45206 11.7284
226 2BOS GLA GAL GLC 0.0005069 0.46258 11.7647
227 2BOS GLA GAL GLC NBU 0.0005445 0.46052 11.7647
228 4M1U MBG A2G 0.001336 0.47809 11.7845
229 5C83 4YN 0.01234 0.40029 11.8182
230 3NK7 SAM 0.006471 0.43704 12.2744
231 1KQP ADJ 0.000003805 0.65829 12.5461
232 5KVM THR TYR PHE ALA VAL LEU MET VAL SER 0.005701 0.45439 12.6316
233 2I0D MUT 0.02304 0.43811 13.1313
234 4YEF 4CQ 0.01482 0.41826 13.4831
235 2VSL MAA LYS PRO PHE 0.01034 0.40772 13.5417
236 5L2Z 70C 0.001741 0.48777 13.7931
237 5KY9 GDP 0.024 0.40038 15
238 5DM1 SAH 0.04105 0.41809 15.7303
239 1K97 CIR 0.0008204 0.50131 15.8242
240 1K97 ASP 0.0008204 0.50131 15.8242
241 5J8O 6GZ 0.01755 0.40212 16.129
242 1MJH ATP 0.0007696 0.47795 16.6667
243 5A89 ADP 0.03963 0.40382 17.3077
244 5A89 FMN 0.03963 0.40382 17.3077
245 2RI1 GLP 0.01208 0.4041 17.4468
246 4CNG SAH 0.002777 0.46441 17.6471
247 3FIU AMP 0.0000003201 0.50242 19.2771
248 1O97 FAD 0.001541 0.48675 19.697
249 1O97 AMP 0.001541 0.48675 19.697
250 1O94 AMP 0.0003077 0.48425 19.697
251 5UDS ATP 0.00002749 0.4411 23.0769
252 3LF0 ATP 0.01306 0.42 23.6842
253 1XNG ATP 0.000001019 0.43253 29.1045
254 1T57 FMN 0.02979 0.40387 30.0971
255 5HQ0 LZ9 0.0383 0.4007 30.9524
Pocket No.: 8; Query (leader) PDB : 1GPM; Ligand: CIT; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1gpm.bio1) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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